locus-tag	class	description
CP980_RS00030	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP980_RS00060	COG0326	Molecular chaperone. Has ATPase activity
CP980_RS00140	COG2267	carboxylic ester hydrolase activity
CP980_RS00195	COG0515	serine threonine protein kinase
CP980_RS00205	COG2267	carboxylic ester hydrolase activity
CP980_RS00210	COG1132	(ABC) transporter
CP980_RS00215	COG1132	(ABC) transporter
CP980_RS00225	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP980_RS00230	COG1733	regulation of RNA biosynthetic process
CP980_RS00340	COG0604	alcohol dehydrogenase
CP980_RS00340	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS00340	COG3321	synthase
CP980_RS00380	COG0596	Alpha beta hydrolase
CP980_RS00420	COG1280	lysine exporter protein (LysE YggA)
CP980_RS00485	COG1191	sigma factor activity
CP980_RS00515	COG0598	Magnesium transport protein CorA
CP980_RS00555	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP980_RS00555	COG0515	serine threonine protein kinase
CP980_RS00570	COG0515	serine threonine protein kinase
CP980_RS00570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP980_RS00620	COG1595	DNA-templated transcription, initiation
CP980_RS00650	COG1228	amidohydrolase
CP980_RS00660	COG2267	carboxylic ester hydrolase activity
CP980_RS00670	COG0783	Belongs to the Dps family
CP980_RS00675	COG2259	Doxx family
CP980_RS00680	COG1335	isochorismatase
CP980_RS00695	COG2319	Wd-40 repeat
CP980_RS00695	COG4249	Peptidase C14 caspase catalytic subunit p20
CP980_RS00715	COG4689	acetoacetate decarboxylase
CP980_RS00775	COG0154	amidase activity
CP980_RS00810	COG0395	ABC-type sugar transport system, permease component
CP980_RS00835	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP980_RS00850	COG1349	DNA-binding transcription factor activity
CP980_RS00855	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP980_RS00860	COG1129	ABC transporter
CP980_RS00865	COG1879	ABC-type sugar transport system periplasmic component
CP980_RS00880	COG4948	Mandelate Racemase Muconate Lactonizing
CP980_RS00885	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS00895	COG0800	Aldolase
CP980_RS00900	COG3386	PFAM SMP-30 Gluconolaconase
CP980_RS00905	COG1940	carbohydrate kinase activity
CP980_RS00910	COG1609	Transcriptional regulator
CP980_RS00935	COG1733	regulation of RNA biosynthetic process
CP980_RS00940	COG0702	epimerase
CP980_RS00955	COG0583	DNA-binding transcription factor activity
CP980_RS00990	COG2353	YceI-like domain
CP980_RS01020	COG5343	regulation of RNA biosynthetic process
CP980_RS01025	COG1595	DNA-templated transcription, initiation
CP980_RS01045	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP980_RS01075	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CP980_RS01080	COG1846	Transcriptional regulator
CP980_RS01120	COG3387	PFAM Glycoside hydrolase 15-related
CP980_RS01160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP980_RS01165	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP980_RS01170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CP980_RS01215	COG3903	Transcriptional regulator
CP980_RS01215	COG3629	intracellular signal transduction
CP980_RS01220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP980_RS01245	COG0739	heme binding
CP980_RS01250	COG0477	Major facilitator Superfamily
CP980_RS01255	COG2208	phosphoserine phosphatase activity
CP980_RS01280	COG0477	Major facilitator Superfamily
CP980_RS01295	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP980_RS01350	COG2340	Cysteine-rich secretory protein family
CP980_RS01370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP980_RS01375	COG0785	Cytochrome C biogenesis protein
CP980_RS01390	COG2205	protein histidine kinase activity
CP980_RS01415	COG2124	cytochrome p450
CP980_RS01440	COG2197	response regulator
CP980_RS01470	COG0318	PFAM AMP-dependent synthetase and ligase
CP980_RS01490	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CP980_RS01530	COG3845	ABC transporter
CP980_RS01550	COG1959	2 iron, 2 sulfur cluster binding
CP980_RS01575	COG2366	antibiotic biosynthetic process
CP980_RS01585	COG3629	intracellular signal transduction
CP980_RS01585	COG3903	Transcriptional regulator
CP980_RS01595	COG0596	Alpha beta hydrolase
CP980_RS01600	COG2226	methyltransferase
CP980_RS01650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP980_RS01665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP980_RS01670	COG0254	rRNA binding
CP980_RS01690	COG1024	Enoyl-CoA hydratase
CP980_RS01700	COG1476	TRANSCRIPTIONal
CP980_RS01715	COG1653	transport
CP980_RS01730	COG0402	S-adenosylhomocysteine deaminase activity
CP980_RS01755	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CP980_RS01850	COG2197	response regulator
CP980_RS01875	COG2814	Major facilitator Superfamily
CP980_RS01915	COG0546	phosphoglycolate phosphatase activity
CP980_RS01945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP980_RS01950	COG4106	trans-aconitate 2-methyltransferase activity
CP980_RS01955	COG3250	beta-galactosidase activity
CP980_RS01960	COG0668	transmembrane transport
CP980_RS01970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CP980_RS01975	COG2205	protein histidine kinase activity
CP980_RS01980	COG0745	RESPONSE REGULATOR receiver
CP980_RS02040	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP980_RS02065	COG0222	ribosome binding
CP980_RS02110	COG0477	Major facilitator Superfamily
CP980_RS02115	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CP980_RS02120	COG2135	peptidase activity
CP980_RS02125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP980_RS02145	COG1595	DNA-templated transcription, initiation
CP980_RS02150	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP980_RS02160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP980_RS02175	COG1764	response to oxidative stress
CP980_RS02180	COG1846	Transcriptional regulator
CP980_RS02195	COG0277	FAD linked oxidase domain protein
CP980_RS02250	COG0009	L-threonylcarbamoyladenylate synthase
CP980_RS02270	COG1376	ErfK ybiS ycfS ynhG family protein
CP980_RS02290	COG1007	ATP synthesis coupled electron transport
CP980_RS02295	COG1006	Multisubunit Na H antiporter MnhC subunit
CP980_RS02300	COG2111	Na H antiporter
CP980_RS02325	COG0309	Hydrogenase expression formation protein (HypE)
CP980_RS02335	COG0298	carbon dioxide binding
CP980_RS02340	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CP980_RS02345	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP980_RS02350	COG0375	protein maturation
CP980_RS02390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP980_RS02390	COG1024	Enoyl-CoA hydratase
CP980_RS02450	COG3903	Transcriptional regulator
CP980_RS02450	COG3629	intracellular signal transduction
CP980_RS02470	COG2197	response regulator
CP980_RS02475	COG4585	Histidine kinase
CP980_RS02485	COG0583	DNA-binding transcription factor activity
CP980_RS02495	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS02510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP980_RS02545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP980_RS02550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP980_RS02560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP980_RS02615	COG2124	cytochrome p450
CP980_RS02620	COG2124	cytochrome p450
CP980_RS02635	COG4106	trans-aconitate 2-methyltransferase activity
CP980_RS02660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP980_RS02675	COG3284	Transcriptional regulator
CP980_RS02685	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP980_RS02695	COG0243	molybdopterin cofactor binding
CP980_RS02710	COG0583	DNA-binding transcription factor activity
CP980_RS02720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP980_RS02720	COG3321	synthase
CP980_RS02735	COG1819	glycosyl
CP980_RS02740	COG4106	trans-aconitate 2-methyltransferase activity
CP980_RS02750	COG3511	phospholipase C
CP980_RS02755	COG2340	Cysteine-rich secretory protein family
CP980_RS02775	COG0745	RESPONSE REGULATOR receiver
CP980_RS02780	COG2205	protein histidine kinase activity
CP980_RS02785	COG1136	(ABC) transporter
CP980_RS02785	COG0577	efflux transmembrane transporter activity
CP980_RS02790	COG1136	(ABC) transporter
CP980_RS02790	COG0577	efflux transmembrane transporter activity
CP980_RS02815	COG0693	protein deglycase activity
CP980_RS02840	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CP980_RS02860	COG0456	acetyltransferase
CP980_RS02870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP980_RS02875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP980_RS02900	COG1021	2,3-dihydroxybenzoate-AMP ligase
CP980_RS02925	COG2124	cytochrome p450
CP980_RS02935	COG0515	serine threonine protein kinase
CP980_RS02945	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP980_RS02955	COG2080	2 iron, 2 sulfur cluster binding
CP980_RS02970	COG2124	cytochrome p450
CP980_RS03010	COG3118	belongs to the thioredoxin family
CP980_RS03010	COG0492	ferredoxin-NADP+ reductase activity
CP980_RS03015	COG1064	alcohol dehydrogenase
CP980_RS03020	COG0477	Major facilitator Superfamily
CP980_RS03025	COG2326	polyphosphate kinase activity
CP980_RS03055	COG0488	(ABC) transporter
CP980_RS03060	COG3631	Ketosteroid isomerase-related protein
CP980_RS03065	COG0702	epimerase
CP980_RS03080	COG0531	amino acid
CP980_RS03150	COG5492	domain, Protein
CP980_RS03150	COG4932	domain protein
CP980_RS03175	COG1070	Carbohydrate kinase
CP980_RS03180	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS03180	COG3347	Dehydrogenase
CP980_RS03185	COG4952	isomerase
CP980_RS03190	COG1609	Transcriptional regulator
CP980_RS03225	COG1846	Transcriptional regulator
CP980_RS03260	COG0477	Major facilitator Superfamily
CP980_RS03295	COG0395	ABC-type sugar transport system, permease component
CP980_RS03310	COG3979	chitinase
CP980_RS03320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP980_RS03335	COG1796	DNA polymerase
CP980_RS03335	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP980_RS03375	COG2272	Belongs to the type-B carboxylesterase lipase family
CP980_RS03405	COG0714	Associated with various cellular activities
CP980_RS03435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP980_RS03450	COG2319	Wd-40 repeat
CP980_RS03450	COG4249	Peptidase C14 caspase catalytic subunit p20
CP980_RS03510	COG0477	Major facilitator Superfamily
CP980_RS03530	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP980_RS03545	COG3448	diguanylate cyclase activity
CP980_RS03545	COG4175	Glycine betaine
CP980_RS03550	COG1191	sigma factor activity
CP980_RS03560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP980_RS03575	COG4264	IucA IucC family
CP980_RS03580	COG4264	IucA IucC family
CP980_RS03585	COG2226	methyltransferase
CP980_RS03595	COG0277	FAD linked oxidase domain protein
CP980_RS03615	COG4585	Histidine kinase
CP980_RS03620	COG2197	response regulator
CP980_RS03650	COG1132	(ABC) transporter
CP980_RS03670	COG3265	gluconokinase activity
CP980_RS03705	COG4412	M6 family metalloprotease domain protein
CP980_RS03705	COG4412	M6 family metalloprotease domain protein
CP980_RS03705	COG1404	Belongs to the peptidase S8 family
CP980_RS03705	COG1404	Belongs to the peptidase S8 family
CP980_RS03710	COG0477	Major facilitator Superfamily
CP980_RS03730	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CP980_RS03745	COG1793	dna ligase
CP980_RS03750	COG1131	(ABC) transporter
CP980_RS03765	COG0667	Aldo Keto reductase
CP980_RS03770	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP980_RS03800	COG0395	ABC-type sugar transport system, permease component
CP980_RS03805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP980_RS03815	COG1609	Transcriptional regulator
CP980_RS03820	COG0673	inositol 2-dehydrogenase activity
CP980_RS03835	COG5492	domain, Protein
CP980_RS03855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP980_RS03875	COG0667	Aldo Keto reductase
CP980_RS03885	COG0800	Aldolase
CP980_RS03890	COG1414	Transcriptional regulator
CP980_RS03905	COG0076	glutamate decarboxylase activity
CP980_RS03920	COG4565	transcriptional regulatory protein
CP980_RS03925	COG3290	protein histidine kinase activity
CP980_RS03930	COG1301	dicarboxylic acid transport
CP980_RS03970	COG3511	phospholipase C
CP980_RS03975	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP980_RS03995	COG2304	oxidoreductase activity
CP980_RS04015	COG1960	acyl-CoA dehydrogenase activity
CP980_RS04020	COG1960	acyl-CoA dehydrogenase activity
CP980_RS04045	COG1024	Enoyl-CoA hydratase
CP980_RS04080	COG2197	response regulator
CP980_RS04085	COG4585	Histidine kinase
CP980_RS04095	COG1131	(ABC) transporter
CP980_RS04105	COG2815	serine threonine protein kinase
CP980_RS04105	COG0515	serine threonine protein kinase
CP980_RS04115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CP980_RS04120	COG2261	transglycosylase associated protein
CP980_RS04145	COG3864	Putative metallopeptidase domain
CP980_RS04170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP980_RS04180	COG2356	endonuclease I
CP980_RS04195	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP980_RS04205	COG2814	Major facilitator Superfamily
CP980_RS04230	COG1215	transferase activity, transferring glycosyl groups
CP980_RS04240	COG0366	Alpha amylase catalytic
CP980_RS04240	COG1470	cell adhesion involved in biofilm formation
CP980_RS04245	COG0393	Putative heavy-metal-binding
CP980_RS04250	COG2197	response regulator
CP980_RS04255	COG4585	Histidine kinase
CP980_RS04305	COG0367	asparagine synthase
CP980_RS04325	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS04335	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP980_RS04345	COG1191	sigma factor activity
CP980_RS04365	COG3290	protein histidine kinase activity
CP980_RS04375	COG0673	inositol 2-dehydrogenase activity
CP980_RS04395	COG0577	efflux transmembrane transporter activity
CP980_RS04395	COG1136	(ABC) transporter
CP980_RS04415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP980_RS04450	COG2815	serine threonine protein kinase
CP980_RS04450	COG0515	serine threonine protein kinase
CP980_RS04495	COG0346	lactoylglutathione lyase activity
CP980_RS04540	COG2326	polyphosphate kinase activity
CP980_RS04565	COG1473	amidohydrolase
CP980_RS04575	COG0277	FAD linked oxidase domain protein
CP980_RS04585	COG0667	Aldo Keto reductase
CP980_RS04595	COG0726	polysaccharide deacetylase
CP980_RS04610	COG1609	Transcriptional regulator
CP980_RS04620	COG0402	S-adenosylhomocysteine deaminase activity
CP980_RS04625	COG2233	PERMEase
CP980_RS04650	COG0671	phosphoesterase, PA-phosphatase related
CP980_RS04660	COG4999	Histidine kinase
CP980_RS04660	COG3850	Histidine kinase
CP980_RS04660	COG3437	response regulator, receiver
CP980_RS04660	COG2205	protein histidine kinase activity
CP980_RS04675	COG1191	sigma factor activity
CP980_RS04720	COG2197	response regulator
CP980_RS04725	COG1132	(ABC) transporter
CP980_RS04730	COG1132	(ABC) transporter
CP980_RS04740	COG0515	serine threonine protein kinase
CP980_RS04750	COG1295	ribonuclease BN
CP980_RS04750	COG1959	2 iron, 2 sulfur cluster binding
CP980_RS04755	COG0432	Pfam Uncharacterised protein family UPF0047
CP980_RS04760	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP980_RS04765	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP980_RS04775	COG2814	Major facilitator Superfamily
CP980_RS04785	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP980_RS04790	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CP980_RS04805	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS04815	COG1764	response to oxidative stress
CP980_RS04835	COG0259	pyridoxamine-phosphate oxidase activity
CP980_RS04840	COG1278	Cold shock
CP980_RS04885	COG0542	response to heat
CP980_RS04900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP980_RS04905	COG0443	Heat shock 70 kDa protein
CP980_RS04930	COG2813	Specifically methylates the guanine in position
CP980_RS04970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP980_RS04980	COG0183	Belongs to the thiolase family
CP980_RS04985	COG1609	Transcriptional regulator
CP980_RS04995	COG0596	Alpha beta hydrolase
CP980_RS05005	COG1595	DNA-templated transcription, initiation
CP980_RS05010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP980_RS05020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP980_RS05035	COG1902	pentaerythritol trinitrate reductase activity
CP980_RS05045	COG4122	O-methyltransferase activity
CP980_RS05060	COG3572	ergothioneine biosynthetic process
CP980_RS05065	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP980_RS05070	COG0121	glutamine amidotransferase
CP980_RS05075	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CP980_RS05090	COG2182	Extracellular solute-binding protein
CP980_RS05095	COG3360	Dodecin
CP980_RS05105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP980_RS05120	COG0438	transferase activity, transferring glycosyl groups
CP980_RS05125	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP980_RS05130	COG1053	succinate dehydrogenase
CP980_RS05140	COG0583	DNA-binding transcription factor activity
CP980_RS05145	COG1309	transcriptional regulator
CP980_RS05150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP980_RS05195	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP980_RS05195	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP980_RS05225	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP980_RS05280	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CP980_RS05305	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CP980_RS05315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP980_RS05390	COG1902	pentaerythritol trinitrate reductase activity
CP980_RS05390	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP980_RS05400	COG0395	ABC-type sugar transport system, permease component
CP980_RS05405	COG1175	transmembrane transport
CP980_RS05410	COG1653	transport
CP980_RS05435	COG3345	alpha-galactosidase
CP980_RS05450	COG0142	geranyltranstransferase activity
CP980_RS05470	COG2124	cytochrome p450
CP980_RS05485	COG1024	Enoyl-CoA hydratase
CP980_RS05490	COG2207	Transcriptional regulator
CP980_RS05495	COG2223	nitrite transmembrane transporter activity
CP980_RS05500	COG1335	isochorismatase
CP980_RS05535	COG0346	lactoylglutathione lyase activity
CP980_RS05540	COG1556	Lactate utilization protein
CP980_RS05545	COG1139	Iron-sulfur cluster binding protein
CP980_RS05550	COG0247	lactate metabolic process
CP980_RS05560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP980_RS05585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP980_RS05600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP980_RS05620	COG2838	Isocitrate dehydrogenase
CP980_RS05625	COG3152	Membrane
CP980_RS05635	COG0598	Magnesium transport protein CorA
CP980_RS05640	COG3585	molybdate ion transport
CP980_RS05645	COG0583	DNA-binding transcription factor activity
CP980_RS05675	COG2124	cytochrome p450
CP980_RS05680	COG3424	synthase
CP980_RS05685	COG2124	cytochrome p450
CP980_RS05705	COG2274	protein secretion by the type I secretion system
CP980_RS05710	COG2274	protein secretion by the type I secretion system
CP980_RS05750	COG3959	Transketolase, thiamine diphosphate binding domain
CP980_RS05755	COG3958	Transketolase
CP980_RS05790	COG2755	lipolytic protein G-D-S-L family
CP980_RS05800	COG2365	Tyrosine phosphatase family
CP980_RS05820	COG1657	PFAM Prenyltransferase squalene oxidase
CP980_RS05830	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP980_RS05840	COG1562	ergosterol biosynthetic process
CP980_RS05845	COG1134	teichoic acid transport
CP980_RS05865	COG0371	Dehydrogenase
CP980_RS05880	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP980_RS05890	COG1024	Enoyl-CoA hydratase
CP980_RS05900	COG4977	sequence-specific DNA binding
CP980_RS05905	COG0488	(ABC) transporter
CP980_RS05910	COG0300	oxidoreductase activity
CP980_RS05970	COG0789	Transcriptional regulator
CP980_RS05985	COG1024	Enoyl-CoA hydratase
CP980_RS05985	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP980_RS05990	COG0183	Belongs to the thiolase family
CP980_RS05995	COG1960	acyl-CoA dehydrogenase activity
CP980_RS06000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP980_RS06005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP980_RS06015	COG3268	Saccharopine dehydrogenase
CP980_RS06020	COG1515	deoxyribonuclease V activity
CP980_RS06055	COG0488	(ABC) transporter
CP980_RS06080	COG1793	dna ligase
CP980_RS06095	COG0494	nUDIX hydrolase
CP980_RS06115	COG1486	melibiose metabolic process
CP980_RS06150	COG1288	antiporter activity
CP980_RS06155	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP980_RS06185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CP980_RS06190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP980_RS06230	COG0656	L-ascorbic acid biosynthetic process
CP980_RS06240	COG2154	pterin-4-alpha-carbinolamine dehydratase
CP980_RS06275	COG1902	pentaerythritol trinitrate reductase activity
CP980_RS06275	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP980_RS06280	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP980_RS06290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP980_RS06300	COG0531	amino acid
CP980_RS06355	COG2226	methyltransferase
CP980_RS06365	COG2362	D-Aminopeptidase
CP980_RS06370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP980_RS06400	COG2755	lipolytic protein G-D-S-L family
CP980_RS06430	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP980_RS06440	COG0604	alcohol dehydrogenase
CP980_RS06445	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP980_RS06445	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP980_RS06460	COG1960	acyl-CoA dehydrogenase activity
CP980_RS06465	COG0688	phosphatidylethanolamine metabolic process
CP980_RS06480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP980_RS06495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP980_RS06500	COG1929	Belongs to the glycerate kinase type-1 family
CP980_RS06505	COG1335	isochorismatase
CP980_RS06525	COG1752	Esterase of the alpha-beta hydrolase superfamily
CP980_RS06535	COG0514	ATP-dependent DNA helicase (RecQ)
CP980_RS06550	COG0483	inositol monophosphate 1-phosphatase activity
CP980_RS06555	COG1953	Uracil, thiamine, allantoin
CP980_RS06565	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP980_RS06570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP980_RS06575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP980_RS06605	COG0405	Gamma-glutamyltransferase
CP980_RS06625	COG2205	protein histidine kinase activity
CP980_RS06630	COG0745	RESPONSE REGULATOR receiver
CP980_RS06645	COG1376	ErfK ybiS ycfS ynhG family protein
CP980_RS06655	COG0765	amino acid transport
CP980_RS06660	COG0765	amino acid transport
CP980_RS06665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP980_RS06670	COG1126	abc transporter atp-binding protein
CP980_RS06700	COG1129	ABC transporter
CP980_RS06715	COG0673	inositol 2-dehydrogenase activity
CP980_RS06725	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS06730	COG4266	Belongs to the allantoicase family
CP980_RS06735	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP980_RS06740	COG1414	Transcriptional regulator
CP980_RS06745	COG1136	(ABC) transporter
CP980_RS06760	COG2197	response regulator
CP980_RS06775	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CP980_RS06785	COG1309	transcriptional regulator
CP980_RS06790	COG0300	oxidoreductase activity
CP980_RS06800	COG2233	PERMEase
CP980_RS06815	COG2351	hydroxyisourate hydrolase activity
CP980_RS06835	COG3622	Belongs to the hyi family
CP980_RS06840	COG2084	Dehydrogenase
CP980_RS06845	COG0753	catalase activity
CP980_RS06850	COG0187	DNA topoisomerase II activity
CP980_RS06855	COG3960	tartronate-semialdehyde synthase activity
CP980_RS06865	COG0386	Belongs to the glutathione peroxidase family
CP980_RS06870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP980_RS06880	COG0598	Magnesium transport protein CorA
CP980_RS06910	COG1442	glycosyl transferase family 8
CP980_RS06945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP980_RS06965	COG0515	serine threonine protein kinase
CP980_RS06975	COG0598	Magnesium transport protein CorA
CP980_RS07030	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP980_RS07050	COG0300	oxidoreductase activity
CP980_RS07100	COG4552	Acetyltransferase involved in intracellular survival and related
CP980_RS07115	COG2252	PERMEase
CP980_RS07120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP980_RS07145	COG1802	Transcriptional regulator
CP980_RS07165	COG0028	Belongs to the TPP enzyme family
CP980_RS07175	COG1404	Belongs to the peptidase S8 family
CP980_RS07195	COG1162	GTPase activity
CP980_RS07215	COG1960	acyl-CoA dehydrogenase activity
CP980_RS07240	COG0175	sulfate reduction
CP980_RS07245	COG0529	Catalyzes the synthesis of activated sulfate
CP980_RS07265	COG1116	anion transmembrane transporter activity
CP980_RS07270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP980_RS07290	COG0667	Aldo Keto reductase
CP980_RS07375	COG3511	phospholipase C
CP980_RS07435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP980_RS07440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP980_RS07465	COG2124	cytochrome p450
CP980_RS07490	COG2197	response regulator
CP980_RS07510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP980_RS07515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CP980_RS07545	COG2326	polyphosphate kinase activity
CP980_RS07570	COG3220	belongs to the UPF0276 family
CP980_RS07590	COG0596	Alpha beta hydrolase
CP980_RS07595	COG3253	May function as heme-dependent peroxidase
CP980_RS07600	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP980_RS07610	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP980_RS07615	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CP980_RS07630	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CP980_RS07640	COG0183	Belongs to the thiolase family
CP980_RS07645	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP980_RS07645	COG1024	Enoyl-CoA hydratase
CP980_RS07665	COG2755	lipolytic protein G-D-S-L family
CP980_RS07685	COG1316	TRANSCRIPTIONal
CP980_RS07690	COG0531	amino acid
CP980_RS07695	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP980_RS07700	COG4214	carbohydrate transport
CP980_RS07710	COG4213	ABC transporter substrate-binding protein
CP980_RS07715	COG1940	carbohydrate kinase activity
CP980_RS07725	COG1285	pathogenesis
CP980_RS07730	COG0395	ABC-type sugar transport system, permease component
CP980_RS07735	COG1175	transmembrane transport
CP980_RS07740	COG1653	transport
CP980_RS07745	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP980_RS07760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP980_RS07780	COG4608	Belongs to the ABC transporter superfamily
CP980_RS07795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP980_RS07830	COG3938	Belongs to the proline racemase family
CP980_RS07850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP980_RS07850	COG2022	thiamine diphosphate biosynthetic process
CP980_RS07860	COG0006	proline dipeptidase activity
CP980_RS07890	COG1902	pentaerythritol trinitrate reductase activity
CP980_RS07895	COG1024	Enoyl-CoA hydratase
CP980_RS07905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP980_RS07910	COG2235	arginine
CP980_RS07920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CP980_RS07935	COG2040	homocysteine
CP980_RS07965	COG1799	cell septum assembly
CP980_RS07980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP980_RS07985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP980_RS08005	COG0431	NADPH-dependent FMN reductase
CP980_RS08030	COG0252	asparaginase activity
CP980_RS08040	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP980_RS08045	COG2814	Major facilitator Superfamily
CP980_RS08055	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP980_RS08085	COG2814	Major facilitator Superfamily
CP980_RS08090	COG3321	synthase
CP980_RS08090	COG0604	alcohol dehydrogenase
CP980_RS08095	COG0640	Transcriptional regulator
CP980_RS08190	COG1201	RNA secondary structure unwinding
CP980_RS08195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CP980_RS08200	COG0531	amino acid
CP980_RS08205	COG0569	domain protein
CP980_RS08240	COG0756	dUTP diphosphatase activity
CP980_RS08265	COG2205	protein histidine kinase activity
CP980_RS08270	COG0745	RESPONSE REGULATOR receiver
CP980_RS08280	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CP980_RS08330	COG1435	thymidine kinase activity
CP980_RS08350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP980_RS08355	COG1802	Transcriptional regulator
CP980_RS08370	COG0612	Peptidase, M16
CP980_RS08375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP980_RS08390	COG0372	Belongs to the citrate synthase family
CP980_RS08400	COG0366	Alpha amylase catalytic
CP980_RS08405	COG0395	ABC-type sugar transport system, permease component
CP980_RS08410	COG1175	transmembrane transport
CP980_RS08430	COG3290	protein histidine kinase activity
CP980_RS08435	COG4565	transcriptional regulatory protein
CP980_RS08440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP980_RS08465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP980_RS08510	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CP980_RS08555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP980_RS08560	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CP980_RS08565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP980_RS08600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP980_RS08610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP980_RS08615	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CP980_RS08625	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CP980_RS08645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP980_RS08660	COG1609	Transcriptional regulator
CP980_RS08675	COG2205	protein histidine kinase activity
CP980_RS08685	COG1126	abc transporter atp-binding protein
CP980_RS08690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP980_RS08695	COG0765	amino acid transport
CP980_RS08700	COG0765	amino acid transport
CP980_RS08730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CP980_RS08740	COG0628	permease
CP980_RS08770	COG1201	RNA secondary structure unwinding
CP980_RS08780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP980_RS08785	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS08795	COG1396	sequence-specific DNA binding
CP980_RS08800	COG1546	Belongs to the CinA family
CP980_RS08800	COG1058	Belongs to the CinA family
CP980_RS08810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP980_RS08820	COG1674	ftsk spoiiie
CP980_RS08830	COG2205	protein histidine kinase activity
CP980_RS08830	COG3437	response regulator, receiver
CP980_RS08830	COG4999	Histidine kinase
CP980_RS08830	COG3850	Histidine kinase
CP980_RS08835	COG2770	Histidine kinase
CP980_RS08835	COG2208	phosphoserine phosphatase activity
CP980_RS08870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CP980_RS08875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP980_RS08880	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CP980_RS08900	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CP980_RS08905	COG0612	Peptidase, M16
CP980_RS08910	COG1185	polyribonucleotide nucleotidyltransferase activity
CP980_RS08915	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CP980_RS08925	COG1674	ftsk spoiiie
CP980_RS08945	COG1404	Belongs to the peptidase S8 family
CP980_RS08965	COG0455	bacterial-type flagellum organization
CP980_RS08975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CP980_RS08980	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CP980_RS08990	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CP980_RS09005	COG0779	Required for maturation of 30S ribosomal subunits
CP980_RS09030	COG0442	prolyl-tRNA aminoacylation
CP980_RS09045	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CP980_RS09050	COG0750	zinc metalloprotease
CP980_RS09055	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CP980_RS09070	COG1012	belongs to the aldehyde dehydrogenase family
CP980_RS09075	COG2508	Transcriptional regulator
CP980_RS09105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP980_RS09110	COG1177	transmembrane transport
CP980_RS09115	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP980_RS09120	COG3842	ATPase activity
CP980_RS09125	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CP980_RS09150	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP980_RS09155	COG0584	glycerophosphoryl diester phosphodiesterase
CP980_RS09160	COG4585	Histidine kinase
CP980_RS09165	COG2197	response regulator
CP980_RS09185	COG1012	belongs to the aldehyde dehydrogenase family
CP980_RS09195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP980_RS09220	COG3842	ATPase activity
CP980_RS09235	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CP980_RS09240	COG0575	Belongs to the CDS family
CP980_RS09245	COG0233	cytoplasmic translational termination
CP980_RS09250	COG0528	UMP kinase activity
CP980_RS09255	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CP980_RS09260	COG0052	Belongs to the universal ribosomal protein uS2 family
CP980_RS09275	COG1191	sigma factor activity
CP980_RS09330	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP980_RS09335	COG0494	nUDIX hydrolase
CP980_RS09385	COG0792	nuclease activity
CP980_RS09420	COG0335	large ribosomal subunit rRNA binding
CP980_RS09425	COG0336	Belongs to the RNA methyltransferase TrmD family
CP980_RS09430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CP980_RS09435	COG1837	Belongs to the UPF0109 family
CP980_RS09440	COG0228	four-way junction DNA binding
CP980_RS09450	COG0442	prolyl-tRNA aminoacylation
CP980_RS09460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP980_RS09470	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CP980_RS09510	COG0477	Major facilitator Superfamily
CP980_RS09515	COG1196	nuclear chromosome segregation
CP980_RS09525	COG1254	Belongs to the acylphosphatase family
CP980_RS09530	COG2340	Cysteine-rich secretory protein family
CP980_RS09535	COG1733	regulation of RNA biosynthetic process
CP980_RS09540	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP980_RS09545	COG0571	ribonuclease III activity
CP980_RS09550	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CP980_RS09565	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CP980_RS09570	COG0742	ribosomal rna small subunit methyltransferase
CP980_RS09575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CP980_RS09580	COG1461	Dihydroxyacetone kinase
CP980_RS09585	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP980_RS09590	COG0351	phosphomethylpyrimidine kinase
CP980_RS09610	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP980_RS09615	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP980_RS09625	COG1920	GTP binding
CP980_RS09630	COG0776	regulation of translation
CP980_RS09640	COG0066	3-isopropylmalate dehydratase activity
CP980_RS09645	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP980_RS09650	COG1414	Transcriptional regulator
CP980_RS09680	COG1011	Hydrolase
CP980_RS09685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CP980_RS09690	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP980_RS09700	COG5002	protein histidine kinase activity
CP980_RS09705	COG2018	Roadblock/LC7 domain
CP980_RS09725	COG2018	Roadblock/LC7 domain
CP980_RS09745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP980_RS09750	COG2353	YceI-like domain
CP980_RS09760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP980_RS09770	COG1309	transcriptional regulator
CP980_RS09775	COG2957	Belongs to the agmatine deiminase family
CP980_RS09780	COG0804	urea catabolic process
CP980_RS09785	COG0832	Belongs to the urease beta subunit family
CP980_RS09785	COG0831	urea catabolic process
CP980_RS09800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP980_RS09805	COG0473	3-isopropylmalate dehydrogenase activity
CP980_RS09815	COG0583	DNA-binding transcription factor activity
CP980_RS09820	COG2130	NADP-dependent
CP980_RS09825	COG3511	phospholipase C
CP980_RS09850	COG1012	belongs to the aldehyde dehydrogenase family
CP980_RS09855	COG0506	proline dehydrogenase activity
CP980_RS09860	COG3835	regulator
CP980_RS09875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CP980_RS09880	COG0440	acetolactate synthase activity
CP980_RS09900	COG0667	Aldo Keto reductase
CP980_RS09905	COG2133	pyrroloquinoline quinone binding
CP980_RS09910	COG2197	response regulator
CP980_RS09920	COG2409	Drug exporters of the RND superfamily
CP980_RS09935	COG2318	DinB family
CP980_RS09940	COG2375	cellular response to nickel ion
CP980_RS09940	COG1132	(ABC) transporter
CP980_RS09955	COG2815	serine threonine protein kinase
CP980_RS09955	COG0515	serine threonine protein kinase
CP980_RS09960	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP980_RS09970	COG0154	amidase activity
CP980_RS09975	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP980_RS09985	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP980_RS10020	COG0482	sulfurtransferase activity
CP980_RS10040	COG2860	membrane
CP980_RS10045	COG4608	Belongs to the ABC transporter superfamily
CP980_RS10050	COG0444	Belongs to the ABC transporter superfamily
CP980_RS10060	COG0747	negative chemotaxis
CP980_RS10085	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP980_RS10090	COG0509	glycine decarboxylation via glycine cleavage system
CP980_RS10095	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP980_RS10100	COG1760	l-serine dehydratase
CP980_RS10115	COG0310	cobalt ion transport
CP980_RS10120	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CP980_RS10130	COG1122	ATPase activity
CP980_RS10180	COG1376	ErfK ybiS ycfS ynhG family protein
CP980_RS10200	COG0297	glycogen (starch) synthase activity
CP980_RS10205	COG0489	protein tyrosine kinase activity
CP980_RS10265	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CP980_RS10270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP980_RS10275	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP980_RS10300	COG1522	sequence-specific DNA binding
CP980_RS10305	COG0058	SHG alpha-glucan phosphorylase activity
CP980_RS10315	COG0366	Alpha amylase catalytic
CP980_RS10320	COG0366	Alpha amylase catalytic
CP980_RS10325	COG3281	Trehalose synthase
CP980_RS10335	COG3118	belongs to the thioredoxin family
CP980_RS10355	COG0205	6-phosphofructokinase activity
CP980_RS10360	COG0280	phosphate acetyltransferase
CP980_RS10360	COG0857	belongs to the CobB CobQ family
CP980_RS10365	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CP980_RS10400	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP980_RS10400	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP980_RS10490	COG0183	Belongs to the thiolase family
CP980_RS10545	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CP980_RS10565	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP980_RS10585	COG2197	response regulator
CP980_RS10600	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CP980_RS10605	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CP980_RS10610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CP980_RS10615	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CP980_RS10620	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP980_RS10625	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP980_RS10630	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP980_RS10650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP980_RS10655	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP980_RS10665	COG2890	protein-(glutamine-N5) methyltransferase activity
CP980_RS10670	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CP980_RS10675	COG0254	rRNA binding
CP980_RS10680	COG1316	TRANSCRIPTIONal
CP980_RS10690	COG0083	homoserine kinase activity
CP980_RS10695	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP980_RS10700	COG0460	homoserine dehydrogenase
CP980_RS10705	COG0019	diaminopimelate decarboxylase activity
CP980_RS10710	COG0018	arginyl-trna synthetase
CP980_RS10710	COG0018	arginyl-trna synthetase
CP980_RS10775	COG1132	(ABC) transporter
CP980_RS10780	COG2226	methyltransferase
CP980_RS10820	COG1960	acyl-CoA dehydrogenase activity
CP980_RS10825	COG0667	Aldo Keto reductase
CP980_RS10830	COG3629	intracellular signal transduction
CP980_RS10845	COG2814	Major facilitator Superfamily
CP980_RS10895	COG1942	4-Oxalocrotonate Tautomerase
CP980_RS10920	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CP980_RS10945	COG2267	carboxylic ester hydrolase activity
CP980_RS10955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP980_RS10975	COG4585	Histidine kinase
CP980_RS10980	COG2197	response regulator
CP980_RS10990	COG3608	succinylglutamate desuccinylase aspartoacylase
CP980_RS10990	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CP980_RS11010	COG3285	dna ligase
CP980_RS11010	COG1793	dna ligase
CP980_RS11015	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CP980_RS11045	COG2205	protein histidine kinase activity
CP980_RS11055	COG1309	transcriptional regulator
CP980_RS11070	COG0768	penicillin binding
CP980_RS11075	COG0772	Belongs to the SEDS family
CP980_RS11090	COG0791	NLP P60 protein
CP980_RS11115	COG5002	protein histidine kinase activity
CP980_RS11130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CP980_RS11135	COG2897	thiosulfate sulfurtransferase activity
CP980_RS11160	COG0745	RESPONSE REGULATOR receiver
CP980_RS11165	COG2205	protein histidine kinase activity
CP980_RS11170	COG0567	Dehydrogenase, E1 component
CP980_RS11170	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP980_RS11260	COG0604	alcohol dehydrogenase
CP980_RS11265	COG0281	malic enzyme
CP980_RS11275	COG0765	amino acid transport
CP980_RS11280	COG1126	abc transporter atp-binding protein
CP980_RS11285	COG4106	trans-aconitate 2-methyltransferase activity
CP980_RS11310	COG5640	endopeptidase activity
CP980_RS11325	COG0142	geranyltranstransferase activity
CP980_RS11330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP980_RS11335	COG1959	2 iron, 2 sulfur cluster binding
CP980_RS11340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP980_RS11340	COG1017	nitric oxide dioxygenase activity
CP980_RS11385	COG1597	lipid kinase activity
CP980_RS11400	COG1309	transcriptional regulator
CP980_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS11410	COG0363	glucosamine-6-phosphate deaminase activity
CP980_RS11415	COG1472	Belongs to the glycosyl hydrolase 3 family
CP980_RS11420	COG0395	ABC-type sugar transport system, permease component
CP980_RS11425	COG1175	transmembrane transport
CP980_RS11430	COG2182	Extracellular solute-binding protein
CP980_RS11435	COG2188	Transcriptional regulator
CP980_RS11440	COG1966	Carbon starvation protein
CP980_RS11475	COG0242	peptide deformylase activity
CP980_RS11490	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CP980_RS11490	COG2199	diguanylate cyclase activity
CP980_RS11495	COG5662	AntiSigma factor
CP980_RS11500	COG1595	DNA-templated transcription, initiation
CP980_RS11510	COG2135	peptidase activity
CP980_RS11520	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP980_RS11530	COG2076	Multidrug Resistance protein
CP980_RS11540	COG0483	inositol monophosphate 1-phosphatase activity
CP980_RS11550	COG0753	catalase activity
CP980_RS11575	COG1615	UPF0182 protein
CP980_RS11585	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP980_RS11645	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP980_RS11685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP980_RS11690	COG0210	DNA helicase
CP980_RS11740	COG4172	Belongs to the ABC transporter superfamily
CP980_RS11800	COG0596	Alpha beta hydrolase
CP980_RS11805	COG2095	MarC family integral membrane protein
CP980_RS11825	COG0598	Magnesium transport protein CorA
CP980_RS11860	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP980_RS11865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP980_RS11875	COG1595	DNA-templated transcription, initiation
CP980_RS11895	COG1024	Enoyl-CoA hydratase
CP980_RS11900	COG0519	Catalyzes the synthesis of GMP from XMP
CP980_RS11910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CP980_RS11915	COG1611	Belongs to the LOG family
CP980_RS11920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP980_RS11955	COG2197	response regulator
CP980_RS11960	COG4585	Histidine kinase
CP980_RS11970	COG1131	(ABC) transporter
CP980_RS11995	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP980_RS12005	COG4608	Belongs to the ABC transporter superfamily
CP980_RS12015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP980_RS12020	COG0601	transmembrane transport
CP980_RS12025	COG4166	transmembrane transport
CP980_RS12040	COG4608	Belongs to the ABC transporter superfamily
CP980_RS12050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP980_RS12065	COG1217	gtp-binding protein TYPA
CP980_RS12085	COG1053	succinate dehydrogenase
CP980_RS12095	COG2815	serine threonine protein kinase
CP980_RS12095	COG0515	serine threonine protein kinase
CP980_RS12105	COG1842	Phage shock protein A
CP980_RS12155	COG0697	spore germination
CP980_RS12220	COG0012	GTP binding
CP980_RS12235	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CP980_RS12245	COG1570	exodeoxyribonuclease VII activity
CP980_RS12250	COG1722	exodeoxyribonuclease VII activity
CP980_RS12255	COG0778	Nitroreductase
CP980_RS12285	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CP980_RS12285	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CP980_RS12300	COG0114	fumarate hydratase activity
CP980_RS12315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP980_RS12340	COG1136	(ABC) transporter
CP980_RS12355	COG0450	alkyl hydroperoxide reductase
CP980_RS12360	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP980_RS12380	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CP980_RS12385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP980_RS12390	COG0667	Aldo Keto reductase
CP980_RS12395	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CP980_RS12425	COG0726	polysaccharide deacetylase
CP980_RS12450	COG2885	chlorophyll binding
CP980_RS12470	COG2197	response regulator
CP980_RS12535	COG1414	Transcriptional regulator
CP980_RS12545	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CP980_RS12600	COG3853	Toxic anion resistance protein (TelA)
CP980_RS12615	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CP980_RS12630	COG0463	Glycosyl transferase, family 2
CP980_RS12645	COG1331	Highly conserved protein containing a thioredoxin domain
CP980_RS12660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP980_RS12670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP980_RS12690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP980_RS12700	COG1595	DNA-templated transcription, initiation
CP980_RS12720	COG0501	Belongs to the peptidase M48B family
CP980_RS12730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP980_RS12755	COG1064	alcohol dehydrogenase
CP980_RS12765	COG1376	ErfK ybiS ycfS ynhG family protein
CP980_RS12780	COG2986	histidine ammonia-lyase
CP980_RS12790	COG1024	Enoyl-CoA hydratase
CP980_RS12805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP980_RS12815	COG0424	maF-like protein
CP980_RS12825	COG4770	biotin carboxylase activity
CP980_RS12845	COG1349	DNA-binding transcription factor activity
CP980_RS12865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP980_RS12880	COG2205	protein histidine kinase activity
CP980_RS12885	COG0745	RESPONSE REGULATOR receiver
CP980_RS12890	COG1595	DNA-templated transcription, initiation
CP980_RS12905	COG1012	belongs to the aldehyde dehydrogenase family
CP980_RS12910	COG1012	belongs to the aldehyde dehydrogenase family
CP980_RS12955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP980_RS12980	COG2197	response regulator
CP980_RS12990	COG2814	Major facilitator Superfamily
CP980_RS13020	COG1079	Belongs to the binding-protein-dependent transport system permease family
CP980_RS13030	COG3845	ABC transporter
CP980_RS13035	COG1744	ABC transporter substrate-binding protein PnrA-like
CP980_RS13040	COG1473	amidohydrolase
CP980_RS13040	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP980_RS13050	COG2089	acid synthase
CP980_RS13055	COG1083	cytidylyl-transferase
CP980_RS13065	COG1216	Glycosyl transferase, family 2
CP980_RS13075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP980_RS13085	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP980_RS13085	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP980_RS13100	COG1595	DNA-templated transcription, initiation
CP980_RS13110	COG2009	succinate dehydrogenase
CP980_RS13120	COG1053	succinate dehydrogenase
CP980_RS13125	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP980_RS13160	COG1309	transcriptional regulator
CP980_RS13170	COG1408	metallophosphoesterase
CP980_RS13180	COG1686	Belongs to the peptidase S11 family
CP980_RS13195	COG0180	Tryptophanyl-tRNA synthetase
CP980_RS13200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP980_RS13205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP980_RS13210	COG0754	glutathionylspermidine amidase activity
CP980_RS13225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP980_RS13230	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP980_RS13245	COG0039	L-malate dehydrogenase activity
CP980_RS13255	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP980_RS13265	COG0138	bifunctional purine biosynthesis protein purh
CP980_RS13305	COG0045	succinate-CoA ligase (ADP-forming) activity
CP980_RS13310	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP980_RS13320	COG0714	Associated with various cellular activities
CP980_RS13335	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP980_RS13335	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP980_RS13375	COG2197	response regulator
CP980_RS13410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CP980_RS13410	COG0519	Catalyzes the synthesis of GMP from XMP
CP980_RS13430	COG1012	belongs to the aldehyde dehydrogenase family
CP980_RS13435	COG0515	serine threonine protein kinase
CP980_RS13445	COG0515	serine threonine protein kinase
CP980_RS13450	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP980_RS13475	COG0516	GMP reductase activity
CP980_RS13485	COG1595	DNA-templated transcription, initiation
CP980_RS13500	COG0583	DNA-binding transcription factor activity
CP980_RS13510	COG4221	oxidoreductase activity
CP980_RS13525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CP980_RS13530	COG0745	RESPONSE REGULATOR receiver
CP980_RS13535	COG0642	Histidine kinase
CP980_RS13540	COG1316	TRANSCRIPTIONal
CP980_RS13560	COG0726	polysaccharide deacetylase
CP980_RS13565	COG0726	polysaccharide deacetylase
CP980_RS13585	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP980_RS13610	COG0802	atpase or kinase
CP980_RS13615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP980_RS13620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP980_RS13630	COG0736	holo-[acyl-carrier-protein] synthase activity
CP980_RS13635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP980_RS13645	COG1072	(Pantothenic acid kinase))
CP980_RS13655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP980_RS13660	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CP980_RS13665	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CP980_RS13675	COG0488	(ABC) transporter
CP980_RS13680	COG0101	tRNA pseudouridine synthase activity
CP980_RS13685	COG0203	ribosomal protein L17
CP980_RS13690	COG0202	RNA polymerase activity
CP980_RS13695	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CP980_RS13700	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CP980_RS13705	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CP980_RS13710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CP980_RS13720	COG0563	adenylate kinase activity
CP980_RS13725	COG0201	protein transport
CP980_RS13730	COG0200	Binds to the 23S rRNA
CP980_RS13735	COG1841	ribosomal large subunit assembly
CP980_RS13740	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CP980_RS13745	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CP980_RS13750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CP980_RS13755	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CP980_RS13765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP980_RS13770	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CP980_RS13775	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CP980_RS13780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CP980_RS13785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CP980_RS13790	COG0255	Belongs to the universal ribosomal protein uL29 family
CP980_RS13795	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CP980_RS13800	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CP980_RS13805	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CP980_RS13810	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CP980_RS13815	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CP980_RS13820	COG0089	rRNA binding
CP980_RS13825	COG0088	Forms part of the polypeptide exit tunnel
CP980_RS13830	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CP980_RS13835	COG0051	transcription antitermination factor activity, RNA binding
CP980_RS13865	COG1215	transferase activity, transferring glycosyl groups
CP980_RS13895	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP980_RS13900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP980_RS13905	COG0049	tRNA binding
CP980_RS13910	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CP980_RS13920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CP980_RS13925	COG0085	RNA polymerase activity
CP980_RS13935	COG0222	ribosome binding
CP980_RS13940	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CP980_RS13955	COG0081	regulation of translation
CP980_RS13970	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP980_RS13980	COG0436	Aminotransferase
CP980_RS13985	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP980_RS13995	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CP980_RS14005	COG0477	Major facilitator Superfamily
CP980_RS14020	COG1595	DNA-templated transcription, initiation
CP980_RS14030	COG2030	dehydratase
CP980_RS14035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP980_RS14055	COG0702	epimerase
CP980_RS14070	COG1666	GTP binding
CP980_RS14075	COG0659	secondary active sulfate transmembrane transporter activity
CP980_RS14090	COG0463	Glycosyl transferase, family 2
CP980_RS14095	COG3304	Inner membrane component domain
CP980_RS14100	COG0501	Belongs to the peptidase M48B family
CP980_RS14105	COG1007	ATP synthesis coupled electron transport
CP980_RS14115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP980_RS14120	COG0713	ATP synthesis coupled electron transport
CP980_RS14125	COG0839	Belongs to the complex I subunit 6 family
CP980_RS14130	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP980_RS14135	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP980_RS14140	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP980_RS14145	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP980_RS14150	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP980_RS14170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CP980_RS14170	COG0674	pyruvate-flavodoxin oxidoreductase activity
CP980_RS14175	COG1013	pyruvate-flavodoxin oxidoreductase activity
CP980_RS14180	COG1733	regulation of RNA biosynthetic process
CP980_RS14185	COG0702	epimerase
CP980_RS14215	COG0142	geranyltranstransferase activity
CP980_RS14220	COG3104	oligopeptide transport
CP980_RS14225	COG2936	dipeptidyl-peptidase activity
CP980_RS14230	COG0561	phosphatase activity
CP980_RS14255	COG1007	ATP synthesis coupled electron transport
CP980_RS14265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP980_RS14270	COG0713	ATP synthesis coupled electron transport
CP980_RS14275	COG0839	Belongs to the complex I subunit 6 family
CP980_RS14280	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP980_RS14285	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP980_RS14290	COG1034	ATP synthesis coupled electron transport
CP980_RS14295	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP980_RS14305	COG0649	NAD binding
CP980_RS14310	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP980_RS14315	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP980_RS14345	COG2066	Belongs to the glutaminase family
CP980_RS14350	COG2226	methyltransferase
CP980_RS14370	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP980_RS14380	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP980_RS14385	COG1278	Cold shock
CP980_RS14420	COG3708	Transcriptional regulator
CP980_RS14420	COG2207	Transcriptional regulator
CP980_RS14465	COG0488	(ABC) transporter
CP980_RS14505	COG1301	dicarboxylic acid transport
CP980_RS14520	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP980_RS14530	COG0163	prenyltransferase activity
CP980_RS14550	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CP980_RS14560	COG3361	conserved protein (COG2071)
CP980_RS14585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP980_RS14590	COG1333	cytochrome c biogenesis protein
CP980_RS14595	COG0785	Cytochrome C biogenesis protein
CP980_RS14600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP980_RS14610	COG0406	alpha-ribazole phosphatase activity
CP980_RS14615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP980_RS14630	COG0277	FAD linked oxidase domain protein
CP980_RS14650	COG1733	regulation of RNA biosynthetic process
CP980_RS14665	COG1742	UPF0060 membrane protein
CP980_RS14680	COG1690	Belongs to the RtcB family
CP980_RS14700	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CP980_RS14705	COG0018	arginyl-trna synthetase
CP980_RS14745	COG0655	NAD(P)H dehydrogenase (quinone) activity
CP980_RS14760	COG0655	NAD(P)H dehydrogenase (quinone) activity
CP980_RS14775	COG2146	nitrite reductase [NAD(P)H] activity
CP980_RS14775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP980_RS14785	COG0243	molybdopterin cofactor binding
CP980_RS14790	COG2223	nitrite transmembrane transporter activity
CP980_RS14795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP980_RS14825	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS14855	COG3903	Transcriptional regulator
CP980_RS14855	COG3629	intracellular signal transduction
CP980_RS14870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP980_RS14875	COG0431	NADPH-dependent FMN reductase
CP980_RS14880	COG0439	Biotin carboxylase
CP980_RS14890	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP980_RS14905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP980_RS14915	COG1045	serine acetyltransferase
CP980_RS14925	COG0113	porphobilinogen synthase activity
CP980_RS14950	COG1648	precorrin-2 dehydrogenase activity
CP980_RS14950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP980_RS14955	COG0181	hydroxymethylbilane synthase activity
CP980_RS14960	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CP980_RS14965	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CP980_RS15015	COG0123	including yeast histone deacetylase and acetoin utilization protein
CP980_RS15025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP980_RS15050	COG0180	Tryptophanyl-tRNA synthetase
CP980_RS15055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP980_RS15065	COG1129	ABC transporter
CP980_RS15065	COG0842	Transport permease protein
CP980_RS15075	COG4991	sh3 domain protein
CP980_RS15080	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP980_RS15080	COG0515	serine threonine protein kinase
CP980_RS15085	COG0129	dihydroxy-acid dehydratase activity
CP980_RS15095	COG1082	Xylose isomerase domain protein TIM barrel
CP980_RS15100	COG0248	Ppx GppA phosphatase
CP980_RS15120	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CP980_RS15130	COG0671	phosphoesterase, PA-phosphatase related
CP980_RS15140	COG1595	DNA-templated transcription, initiation
CP980_RS15150	COG0745	RESPONSE REGULATOR receiver
CP980_RS15155	COG2205	protein histidine kinase activity
CP980_RS15165	COG0739	heme binding
CP980_RS15195	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CP980_RS15225	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CP980_RS15230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CP980_RS15240	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CP980_RS15260	COG2234	aminopeptidase activity
CP980_RS15295	COG0649	NAD binding
CP980_RS15315	COG1732	Glycine betaine
CP980_RS15325	COG1174	glycine betaine transport
CP980_RS15340	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP980_RS15340	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP980_RS15355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CP980_RS15360	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CP980_RS15375	COG0302	gtp cyclohydrolase
CP980_RS15385	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CP980_RS15390	COG0037	tRNA processing
CP980_RS15400	COG2027	D-alanyl-D-alanine carboxypeptidase
CP980_RS15405	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP980_RS15415	COG0586	Pfam SNARE associated Golgi protein
CP980_RS15420	COG0789	Transcriptional regulator
CP980_RS15425	COG2318	DinB family
CP980_RS15430	COG0768	penicillin binding
CP980_RS15435	COG1012	belongs to the aldehyde dehydrogenase family
CP980_RS15460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP980_RS15470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP980_RS15470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP980_RS15475	COG0456	acetyltransferase
CP980_RS15480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP980_RS15515	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CP980_RS15520	COG2188	Transcriptional regulator
CP980_RS15605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CP980_RS15610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP980_RS15615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP980_RS15615	COG1754	DNA topoisomerase type I activity
CP980_RS15625	COG2890	protein-(glutamine-N5) methyltransferase activity
CP980_RS15635	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CP980_RS15640	COG2172	sigma factor antagonist activity
CP980_RS15645	COG1366	Belongs to the anti-sigma-factor antagonist family
CP980_RS15650	COG1111	helicase
CP980_RS15650	COG1205	dead DEAH box helicase
CP980_RS15715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP980_RS15720	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP980_RS15730	COG0596	Alpha beta hydrolase
CP980_RS15760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP980_RS15785	COG0003	Pfam Anion-transporting ATPase
CP980_RS15800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP980_RS15810	COG1408	metallophosphoesterase
CP980_RS15825	COG0402	S-adenosylhomocysteine deaminase activity
CP980_RS15845	COG1595	DNA-templated transcription, initiation
CP980_RS15865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CP980_RS15870	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CP980_RS15890	COG0463	Glycosyl transferase, family 2
CP980_RS15905	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP980_RS15910	COG0693	protein deglycase activity
CP980_RS15935	COG4585	Histidine kinase
CP980_RS15940	COG2197	response regulator
CP980_RS15950	COG2197	response regulator
CP980_RS15965	COG2124	cytochrome p450
CP980_RS15970	COG3559	Exporter of polyketide antibiotics
CP980_RS15975	COG1131	(ABC) transporter
CP980_RS15990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CP980_RS16000	COG3844	kynureninase activity
CP980_RS16015	COG0191	fructose-bisphosphate aldolase activity
CP980_RS16020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CP980_RS16035	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CP980_RS16070	COG0542	response to heat
CP980_RS16090	COG0789	Transcriptional regulator
CP980_RS16095	COG0484	heat shock protein binding
CP980_RS16100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP980_RS16105	COG0443	Heat shock 70 kDa protein
CP980_RS16115	COG2181	nitrate reductase activity
CP980_RS16115	COG0247	lactate metabolic process
CP980_RS16135	COG0717	Belongs to the dCTP deaminase family
CP980_RS16210	COG2188	Transcriptional regulator
CP980_RS16270	COG0596	Alpha beta hydrolase
CP980_RS16275	COG1595	DNA-templated transcription, initiation
CP980_RS16280	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP980_RS16290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP980_RS16340	COG1289	transmembrane transporter activity
CP980_RS16350	COG2205	protein histidine kinase activity
CP980_RS16360	COG2304	oxidoreductase activity
CP980_RS16365	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CP980_RS16400	COG1960	acyl-CoA dehydrogenase activity
CP980_RS16410	COG1362	aminopeptidase activity
CP980_RS16425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP980_RS16475	COG2271	Major facilitator Superfamily
CP980_RS16480	COG1802	Transcriptional regulator
CP980_RS16520	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP980_RS16525	COG0022	dehydrogenase e1 component
CP980_RS16545	COG0515	serine threonine protein kinase
CP980_RS16550	COG0515	serine threonine protein kinase
CP980_RS16565	COG4591	ABC-type transport system involved in lipoprotein release permease component
CP980_RS16565	COG1136	(ABC) transporter
CP980_RS16590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP980_RS16595	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS16595	COG0604	alcohol dehydrogenase
CP980_RS16595	COG3321	synthase
CP980_RS16615	COG1522	sequence-specific DNA binding
CP980_RS16625	COG1309	transcriptional regulator
CP980_RS16630	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP980_RS16660	COG3396	Phenylacetate-CoA oxygenase
CP980_RS16665	COG3460	Phenylacetate-CoA oxygenase
CP980_RS16670	COG3396	Phenylacetate-CoA oxygenase
CP980_RS16675	COG2151	metal-sulfur cluster biosynthetic enzyme
CP980_RS16680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP980_RS16705	COG2197	response regulator
CP980_RS16710	COG4585	Histidine kinase
CP980_RS16720	COG1716	ATPase activity
CP980_RS16725	COG1716	ATPase activity
CP980_RS16740	COG0768	penicillin binding
CP980_RS16750	COG0515	serine threonine protein kinase
CP980_RS16755	COG3764	Sortase (surface protein transpeptidase)
CP980_RS16760	COG3764	Sortase (surface protein transpeptidase)
CP980_RS16770	COG3764	Sortase (surface protein transpeptidase)
CP980_RS16785	COG0457	Tetratricopeptide repeat
CP980_RS16785	COG0705	Rhomboid family
CP980_RS16800	COG3942	CHAP domain
CP980_RS16800	COG1388	LysM domain
CP980_RS16820	COG0515	serine threonine protein kinase
CP980_RS16845	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP980_RS16855	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CP980_RS16860	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CP980_RS16865	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP980_RS16870	COG0592	DNA-directed DNA polymerase activity
CP980_RS16875	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CP980_RS16890	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CP980_RS16895	COG0706	membrane insertase activity
CP980_RS16905	COG0357	Ribosomal RNA small subunit methyltransferase G
CP980_RS16910	COG1192	Involved in chromosome partitioning
CP980_RS16925	COG3118	belongs to the thioredoxin family
CP980_RS16930	COG0492	ferredoxin-NADP+ reductase activity
CP980_RS16940	COG1595	DNA-templated transcription, initiation
CP980_RS16945	COG2815	serine threonine protein kinase
CP980_RS16945	COG0515	serine threonine protein kinase
CP980_RS16960	COG0617	tRNA 3'-terminal CCA addition
CP980_RS16970	COG1260	myo-inositol-1-phosphate synthase
CP980_RS16980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP980_RS17005	COG0360	Binds together with S18 to 16S ribosomal RNA
CP980_RS17010	COG0629	single-stranded DNA binding
CP980_RS17015	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP980_RS17020	COG0359	binds to the 23S rRNA
CP980_RS17035	COG0305	Participates in initiation and elongation during chromosome replication
CP980_RS17050	COG0456	acetyltransferase
CP980_RS17080	COG0626	cystathionine gamma-synthase activity
CP980_RS17085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP980_RS17090	COG1950	PFAM Membrane protein of
CP980_RS17095	COG0662	Cupin 2, conserved barrel domain protein
CP980_RS17120	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CP980_RS17145	COG1609	Transcriptional regulator
CP980_RS17150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP980_RS17160	COG1271	oxidase subunit
CP980_RS17165	COG1294	oxidase, subunit
CP980_RS17170	COG4988	ABC transporter
CP980_RS17180	COG0561	phosphatase activity
CP980_RS17195	COG0326	Molecular chaperone. Has ATPase activity
CP980_RS17200	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CP980_RS17210	COG0789	Transcriptional regulator
CP980_RS17225	COG1131	(ABC) transporter
CP980_RS17250	COG0561	phosphatase activity
CP980_RS17255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CP980_RS17265	COG2837	iron assimilation
CP980_RS17270	COG2372	response to copper ion
CP980_RS17300	COG0006	proline dipeptidase activity
CP980_RS17320	COG0653	protein targeting
CP980_RS17335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP980_RS17350	COG2855	membrane
CP980_RS17365	COG2801	Transposase and inactivated derivatives
CP980_RS17365	COG3415	Transposase
CP980_RS17385	COG1960	acyl-CoA dehydrogenase activity
CP980_RS17395	COG1960	acyl-CoA dehydrogenase activity
CP980_RS17410	COG1595	DNA-templated transcription, initiation
CP980_RS17415	COG0318	PFAM AMP-dependent synthetase and ligase
CP980_RS17425	COG0745	RESPONSE REGULATOR receiver
CP980_RS17470	COG0745	RESPONSE REGULATOR receiver
CP980_RS17475	COG2205	protein histidine kinase activity
CP980_RS17515	COG1191	sigma factor activity
CP980_RS17560	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CP980_RS17575	COG0433	COG0433 Predicted ATPase
CP980_RS17610	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP980_RS17610	COG2080	2 iron, 2 sulfur cluster binding
CP980_RS17615	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP980_RS17620	COG3835	regulator
CP980_RS17640	COG1595	DNA-templated transcription, initiation
CP980_RS17665	COG0151	Belongs to the GarS family
CP980_RS17680	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CP980_RS17690	COG2197	response regulator
CP980_RS17695	COG3850	Histidine kinase
CP980_RS17715	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP980_RS17720	COG0047	phosphoribosylformylglycinamidine synthase activity
CP980_RS17725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP980_RS17740	COG3119	arylsulfatase activity
CP980_RS17750	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CP980_RS17780	COG1643	Atp-dependent helicase
CP980_RS17795	COG0785	Cytochrome C biogenesis protein
CP980_RS17820	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP980_RS17825	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP980_RS17830	COG0513	Belongs to the DEAD box helicase family
CP980_RS17855	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP980_RS17855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP980_RS17860	COG1045	serine acetyltransferase
CP980_RS17865	COG2022	thiamine diphosphate biosynthetic process
CP980_RS17865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP980_RS17885	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CP980_RS17890	COG4166	transmembrane transport
CP980_RS17900	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP980_RS17945	COG1196	nuclear chromosome segregation
CP980_RS17945	COG0739	heme binding
CP980_RS17945	COG0741	lytic transglycosylase activity
CP980_RS17955	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CP980_RS17960	COG0579	oxidoreductase
CP980_RS17990	COG1252	NADH dehydrogenase
CP980_RS18050	COG3293	Transposase
CP980_RS18120	COG1357	PFAM Pentapeptide repeats (8 copies)
CP980_RS18130	COG1196	nuclear chromosome segregation
CP980_RS18130	COG0741	lytic transglycosylase activity
CP980_RS18130	COG0739	heme binding
CP980_RS18135	COG0671	phosphoesterase, PA-phosphatase related
CP980_RS18155	COG1937	Protein conserved in bacteria
CP980_RS18165	COG0306	phosphate transporter
CP980_RS18170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP980_RS18195	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CP980_RS18200	COG0456	acetyltransferase
CP980_RS18205	COG0737	Belongs to the 5'-nucleotidase family
CP980_RS18210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CP980_RS18220	COG0823	Involved in the tonB-independent uptake of proteins
CP980_RS18230	COG0745	RESPONSE REGULATOR receiver
CP980_RS18235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP980_RS18240	COG1609	Transcriptional regulator
CP980_RS18245	COG0745	RESPONSE REGULATOR receiver
CP980_RS18300	COG3485	protocatechuate 3,4-dioxygenase
CP980_RS18305	COG0735	belongs to the Fur family
CP980_RS18315	COG1490	D-aminoacyl-tRNA deacylase activity
CP980_RS18325	COG4552	Acetyltransferase involved in intracellular survival and related
CP980_RS18330	COG2890	protein-(glutamine-N5) methyltransferase activity
CP980_RS18370	COG0438	transferase activity, transferring glycosyl groups
CP980_RS18385	COG0588	phosphoglycerate mutase activity
CP980_RS18400	COG5002	protein histidine kinase activity
CP980_RS18420	COG1329	Transcriptional regulator
CP980_RS18425	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CP980_RS18430	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CP980_RS18435	COG0215	cysteine-tRNA ligase activity
CP980_RS18460	COG3842	ATPase activity
CP980_RS18520	COG2197	response regulator
CP980_RS18550	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CP980_RS18575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CP980_RS18595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP980_RS18595	COG0561	phosphatase activity
CP980_RS18605	COG0463	Glycosyl transferase, family 2
CP980_RS18635	COG0135	phosphoribosylanthranilate isomerase activity
CP980_RS18640	COG0515	serine threonine protein kinase
CP980_RS18640	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP980_RS18700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP980_RS18700	COG1263	PTS System
CP980_RS18705	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CP980_RS18710	COG1737	Transcriptional regulator
CP980_RS18740	COG3973	AAA domain
CP980_RS18755	COG1061	Type III restriction enzyme res subunit
CP980_RS18790	COG1278	Cold shock
CP980_RS18795	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP980_RS18800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP980_RS18810	COG2814	Major facilitator Superfamily
CP980_RS18830	COG2268	Band 7 protein
CP980_RS18840	COG0667	Aldo Keto reductase
CP980_RS18855	COG2814	Major facilitator Superfamily
CP980_RS18870	COG1487	ribonuclease activity
CP980_RS18880	COG2252	PERMEase
CP980_RS18890	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP980_RS18910	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CP980_RS18915	COG0247	lactate metabolic process
CP980_RS18915	COG0277	FAD linked oxidase domain protein
CP980_RS18940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP980_RS18960	COG1309	transcriptional regulator
CP980_RS18970	COG0259	pyridoxamine-phosphate oxidase activity
CP980_RS18980	COG4821	SIS domain
CP980_RS18990	COG2945	thiolester hydrolase activity
CP980_RS18990	COG0596	Alpha beta hydrolase
CP980_RS19000	COG1131	(ABC) transporter
CP980_RS19050	COG0318	PFAM AMP-dependent synthetase and ligase
CP980_RS19060	COG1960	acyl-CoA dehydrogenase activity
CP980_RS19065	COG1960	acyl-CoA dehydrogenase activity
CP980_RS19075	COG2197	response regulator
CP980_RS19080	COG3851	Histidine kinase
CP980_RS19100	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS19105	COG1960	acyl-CoA dehydrogenase activity
CP980_RS19115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP980_RS19130	COG1024	Enoyl-CoA hydratase
CP980_RS19140	COG2072	flavoprotein involved in K transport
CP980_RS19175	COG1960	acyl-CoA dehydrogenase activity
CP980_RS19195	COG0515	serine threonine protein kinase
CP980_RS19195	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP980_RS19235	COG1024	Enoyl-CoA hydratase
CP980_RS19320	COG0494	nUDIX hydrolase
CP980_RS19330	COG0577	efflux transmembrane transporter activity
CP980_RS19330	COG1136	(ABC) transporter
CP980_RS19335	COG1136	(ABC) transporter
CP980_RS19335	COG0577	efflux transmembrane transporter activity
CP980_RS19355	COG2205	protein histidine kinase activity
CP980_RS19465	COG2365	Tyrosine phosphatase family
CP980_RS19470	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP980_RS19480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP980_RS19505	COG1686	Belongs to the peptidase S11 family
CP980_RS19570	COG0477	Major facilitator Superfamily
CP980_RS19575	COG1349	DNA-binding transcription factor activity
CP980_RS19640	COG0438	transferase activity, transferring glycosyl groups
CP980_RS19640	COG0297	glycogen (starch) synthase activity
CP980_RS19645	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP980_RS19690	COG3118	belongs to the thioredoxin family
CP980_RS19690	COG0492	ferredoxin-NADP+ reductase activity
CP980_RS19740	COG2223	nitrite transmembrane transporter activity
CP980_RS19750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CP980_RS19760	COG0243	molybdopterin cofactor binding
CP980_RS19765	COG0437	4 iron, 4 sulfur cluster binding
CP980_RS19780	COG2223	nitrite transmembrane transporter activity
CP980_RS19800	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CP980_RS19815	COG3263	regulation of cellular component size
CP980_RS19825	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CP980_RS19830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP980_RS19840	COG0315	cyclic pyranopterin monophosphate synthase activity
CP980_RS19845	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP980_RS19845	COG0315	cyclic pyranopterin monophosphate synthase activity
CP980_RS19890	COG0708	Exodeoxyribonuclease III
CP980_RS19900	COG2072	flavoprotein involved in K transport
CP980_RS19905	COG2267	carboxylic ester hydrolase activity
CP980_RS19910	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS19915	COG0793	Belongs to the peptidase S41A family
CP980_RS19915	COG4946	Tricorn protease homolog
CP980_RS19925	COG2409	Drug exporters of the RND superfamily
CP980_RS19935	COG0310	cobalt ion transport
CP980_RS19945	COG1122	ATPase activity
CP980_RS19950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP980_RS19980	COG0084	hydrolase, TatD family'
CP980_RS19985	COG3583	domain protein
CP980_RS19985	COG3584	3D domain protein
CP980_RS19990	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CP980_RS19995	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CP980_RS20005	COG0488	(ABC) transporter
CP980_RS20030	COG2197	response regulator
CP980_RS20035	COG1846	Transcriptional regulator
CP980_RS20040	COG4106	trans-aconitate 2-methyltransferase activity
CP980_RS20045	COG1309	transcriptional regulator
CP980_RS20055	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CP980_RS20060	COG0193	aminoacyl-tRNA hydrolase activity
CP980_RS20065	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CP980_RS20070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP980_RS20075	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CP980_RS20090	COG4585	Histidine kinase
CP980_RS20125	COG0596	Alpha beta hydrolase
CP980_RS20135	COG0477	Major facilitator Superfamily
CP980_RS20140	COG1136	(ABC) transporter
CP980_RS20145	COG0577	efflux transmembrane transporter activity
CP980_RS20165	COG2815	serine threonine protein kinase
CP980_RS20165	COG0515	serine threonine protein kinase
CP980_RS20185	COG1017	nitric oxide dioxygenase activity
CP980_RS20185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP980_RS20190	COG2124	cytochrome p450
CP980_RS20205	COG0148	phosphopyruvate hydratase activity
CP980_RS20230	COG1252	NADH dehydrogenase
CP980_RS20235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP980_RS20240	COG0577	efflux transmembrane transporter activity
CP980_RS20245	COG1136	(ABC) transporter
CP980_RS20275	COG0183	Belongs to the thiolase family
CP980_RS20305	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CP980_RS20320	COG1228	amidohydrolase
CP980_RS20350	COG3104	oligopeptide transport
CP980_RS20355	COG0745	RESPONSE REGULATOR receiver
CP980_RS20360	COG2205	protein histidine kinase activity
CP980_RS20390	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP980_RS20400	COG1316	TRANSCRIPTIONal
CP980_RS20405	COG1316	TRANSCRIPTIONal
CP980_RS20410	COG1316	TRANSCRIPTIONal
CP980_RS20430	COG1316	TRANSCRIPTIONal
CP980_RS20455	COG0778	Nitroreductase
CP980_RS20455	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CP980_RS20460	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP980_RS20495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP980_RS20500	COG2835	tetraacyldisaccharide 4'-kinase activity
CP980_RS20510	COG1482	cell wall glycoprotein biosynthetic process
CP980_RS20520	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CP980_RS20570	COG0714	Associated with various cellular activities
CP980_RS20590	COG0745	RESPONSE REGULATOR receiver
CP980_RS20595	COG5002	protein histidine kinase activity
CP980_RS20595	COG5000	phosphorelay sensor kinase activity
CP980_RS20600	COG0823	Involved in the tonB-independent uptake of proteins
CP980_RS20610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP980_RS20615	COG2197	response regulator
CP980_RS20630	COG0653	protein targeting
CP980_RS20645	COG0546	phosphoglycolate phosphatase activity
CP980_RS20655	COG1134	teichoic acid transport
CP980_RS20655	COG1388	LysM domain
CP980_RS20670	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP980_RS20675	COG0395	ABC-type sugar transport system, permease component
CP980_RS20680	COG1175	transmembrane transport
CP980_RS20685	COG1653	transport
CP980_RS20695	COG0515	serine threonine protein kinase
CP980_RS20700	COG0515	serine threonine protein kinase
CP980_RS20710	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP980_RS20720	COG2884	Cell division ATP-binding protein ftsE
CP980_RS20730	COG0793	Belongs to the peptidase S41A family
CP980_RS20735	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CP980_RS20760	COG0583	DNA-binding transcription factor activity
CP980_RS20785	COG3973	AAA domain
CP980_RS20795	COG0776	regulation of translation
CP980_RS20800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP980_RS20805	COG1678	Uncharacterized ACR, COG1678
CP980_RS20815	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP980_RS20825	COG2080	2 iron, 2 sulfur cluster binding
CP980_RS20845	COG1404	Belongs to the peptidase S8 family
CP980_RS20890	COG3654	unkown
CP980_RS20925	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CP980_RS20935	COG0277	FAD linked oxidase domain protein
CP980_RS20970	COG1335	isochorismatase
CP980_RS20980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CP980_RS20990	COG1113	amino acid transport
CP980_RS21010	COG3189	MarR family transcriptional regulator
CP980_RS21020	COG1234	tRNA 3'-trailer cleavage
CP980_RS21025	COG1263	PTS System
CP980_RS21030	COG1263	PTS System
CP980_RS21035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP980_RS21040	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CP980_RS21050	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CP980_RS21090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP980_RS21105	COG4555	ABC transporter
CP980_RS21115	COG2733	membrane
CP980_RS21180	COG3764	Sortase (surface protein transpeptidase)
CP980_RS21190	COG0706	membrane insertase activity
CP980_RS21195	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP980_RS21200	COG0673	inositol 2-dehydrogenase activity
CP980_RS21220	COG2188	Transcriptional regulator
CP980_RS21225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP980_RS21290	COG3397	chitin binding
CP980_RS21295	COG0318	PFAM AMP-dependent synthetase and ligase
CP980_RS21310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP980_RS21375	COG0406	alpha-ribazole phosphatase activity
CP980_RS21400	COG0745	RESPONSE REGULATOR receiver
CP980_RS21440	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CP980_RS21445	COG4977	sequence-specific DNA binding
CP980_RS21455	COG0589	response to stress
CP980_RS21465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP980_RS21485	COG4264	IucA IucC family
CP980_RS21495	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CP980_RS21500	COG0076	glutamate decarboxylase activity
CP980_RS21505	COG2375	cellular response to nickel ion
CP980_RS21520	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CP980_RS21525	COG1960	acyl-CoA dehydrogenase activity
CP980_RS21540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP980_RS21545	COG1309	transcriptional regulator
CP980_RS21570	COG1946	Acyl-CoA thioesterase
CP980_RS21595	COG0028	Belongs to the TPP enzyme family
CP980_RS21605	COG1802	Transcriptional regulator
CP980_RS21625	COG1472	Belongs to the glycosyl hydrolase 3 family
CP980_RS21640	COG1846	Transcriptional regulator
CP980_RS21640	COG0456	acetyltransferase
CP980_RS21650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP980_RS21675	COG0673	inositol 2-dehydrogenase activity
CP980_RS21680	COG1082	Xylose isomerase domain protein TIM barrel
CP980_RS21690	COG3718	enzyme involved in inositol metabolism
CP980_RS21695	COG3962	Belongs to the TPP enzyme family
CP980_RS21725	COG0454	-acetyltransferase
CP980_RS21725	COG0456	acetyltransferase
CP980_RS21805	COG2346	COG2346, Truncated hemoglobins
CP980_RS21810	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP980_RS21840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP980_RS21855	COG1486	melibiose metabolic process
CP980_RS21860	COG0395	ABC-type sugar transport system, permease component
CP980_RS21865	COG1175	transmembrane transport
CP980_RS21870	COG1653	transport
CP980_RS21880	COG0668	transmembrane transport
CP980_RS21905	COG1846	Transcriptional regulator
CP980_RS21915	COG0697	spore germination
CP980_RS21925	COG0583	DNA-binding transcription factor activity
CP980_RS21945	COG2234	aminopeptidase activity
CP980_RS21980	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP980_RS21985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CP980_RS21990	COG1113	amino acid transport
CP980_RS22000	COG1113	amino acid transport
CP980_RS22010	COG1113	amino acid transport
CP980_RS22015	COG0698	ribose 5-phosphate isomerase
CP980_RS22025	COG4552	Acetyltransferase involved in intracellular survival and related
CP980_RS22035	COG1136	(ABC) transporter
CP980_RS22035	COG0577	efflux transmembrane transporter activity
CP980_RS22045	COG1660	Displays ATPase and GTPase activities
CP980_RS22085	COG0544	peptidyl-prolyl cis-trans isomerase activity
CP980_RS22090	COG0740	serine-type endopeptidase activity
CP980_RS22095	COG0740	serine-type endopeptidase activity
CP980_RS22100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CP980_RS22110	COG0525	valine-tRNA ligase activity
CP980_RS22140	COG1077	Cell shape determining protein MreB Mrl
CP980_RS22145	COG0285	dihydrofolate synthase activity
CP980_RS22155	COG0105	UTP biosynthetic process
CP980_RS22160	COG1077	Cell shape determining protein MreB Mrl
CP980_RS22175	COG0768	penicillin binding
CP980_RS22180	COG0772	Belongs to the SEDS family
CP980_RS22215	COG1530	ribonuclease E activity
CP980_RS22220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CP980_RS22225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CP980_RS22230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CP980_RS22245	COG0438	transferase activity, transferring glycosyl groups
CP980_RS22250	COG0463	Glycosyl transferase, family 2
CP980_RS22250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP980_RS22270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CP980_RS22280	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CP980_RS22295	COG0501	Belongs to the peptidase M48B family
CP980_RS22300	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CP980_RS22310	COG0799	negative regulation of ribosome biogenesis
CP980_RS22315	COG0588	phosphoglycerate mutase activity
CP980_RS22335	COG0495	leucyl-tRNA aminoacylation
CP980_RS22345	COG1307	EDD domain protein, DegV family
CP980_RS22350	COG1555	photosystem II stabilization
CP980_RS22350	COG1596	polysaccharide export
CP980_RS22360	COG2353	YceI-like domain
CP980_RS22375	COG0268	Binds directly to 16S ribosomal RNA
CP980_RS22380	COG0481	GTPase activity
CP980_RS22410	COG1420	regulation of RNA biosynthetic process
CP980_RS22415	COG0484	heat shock protein binding
CP980_RS22420	COG2070	2-Nitropropane dioxygenase
CP980_RS22430	COG0537	adenosine 5'-monophosphoramidase activity
CP980_RS22435	COG1234	tRNA 3'-trailer cleavage
CP980_RS22445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP980_RS22455	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CP980_RS22465	COG2315	Protein conserved in bacteria
CP980_RS22475	COG2814	Major facilitator Superfamily
CP980_RS22490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CP980_RS22510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP980_RS22515	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS22525	COG2233	PERMEase
CP980_RS22530	COG1381	Involved in DNA repair and RecF pathway recombination
CP980_RS22535	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP980_RS22545	COG3415	Transposase
CP980_RS22545	COG2801	Transposase and inactivated derivatives
CP980_RS22555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP980_RS22560	COG1121	(ABC) transporter
CP980_RS22565	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP980_RS22565	COG3443	Belongs to the bacterial solute-binding protein 9 family
CP980_RS22570	COG0423	glycine-tRNA ligase activity
CP980_RS22580	COG1309	transcriptional regulator
CP980_RS22585	COG0667	Aldo Keto reductase
CP980_RS22610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP980_RS22610	COG0574	Belongs to the PEP-utilizing enzyme family
CP980_RS22630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP980_RS22630	COG2146	nitrite reductase [NAD(P)H] activity
CP980_RS22635	COG2146	nitrite reductase [NAD(P)H] activity
CP980_RS22635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP980_RS22645	COG1017	nitric oxide dioxygenase activity
CP980_RS22645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP980_RS22675	COG2205	protein histidine kinase activity
CP980_RS22690	COG0358	DNA primase activity
CP980_RS22700	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CP980_RS22710	COG2949	membrane
CP980_RS22735	COG1070	Carbohydrate kinase
CP980_RS22760	COG0582	viral genome integration into host DNA
CP980_RS22805	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP980_RS22815	COG0825	malonyl-CoA metabolic process
CP980_RS22815	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CP980_RS22825	COG1522	sequence-specific DNA binding
CP980_RS22835	COG1077	Cell shape determining protein MreB Mrl
CP980_RS22840	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CP980_RS22860	COG2130	NADP-dependent
CP980_RS22865	COG1764	response to oxidative stress
CP980_RS22905	COG1309	transcriptional regulator
CP980_RS22925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP980_RS22930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP980_RS22935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP980_RS22950	COG1741	Belongs to the pirin family
CP980_RS22960	COG0789	Transcriptional regulator
CP980_RS22965	COG0667	Aldo Keto reductase
CP980_RS22980	COG1309	transcriptional regulator
CP980_RS22985	COG0477	Major facilitator Superfamily
CP980_RS22995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP980_RS23000	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP980_RS23045	COG1358	cellular component organization or biogenesis
CP980_RS23115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP980_RS23155	COG2124	cytochrome p450
CP980_RS23160	COG0183	Belongs to the thiolase family
CP980_RS23175	COG3845	ABC transporter
CP980_RS23210	COG1309	transcriptional regulator
CP980_RS23215	COG0438	transferase activity, transferring glycosyl groups
CP980_RS23245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP980_RS23290	COG1960	acyl-CoA dehydrogenase activity
CP980_RS23295	COG0183	Belongs to the thiolase family
CP980_RS23320	COG2030	dehydratase
CP980_RS23330	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS23345	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CP980_RS23380	COG0557	exoribonuclease II activity
CP980_RS23385	COG3022	response to hydroperoxide
CP980_RS23400	COG1834	amidinotransferase
CP980_RS23410	COG2814	Major facilitator Superfamily
CP980_RS23415	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS23420	COG0384	phenazine biosynthesis protein PhzF
CP980_RS23430	COG0672	)-iron permease
CP980_RS23435	COG2837	iron assimilation
CP980_RS23450	COG5398	heme oxygenase
CP980_RS23480	COG1994	Peptidase M50
CP980_RS23500	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CP980_RS23510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP980_RS23510	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP980_RS23520	COG2132	Multicopper oxidase
CP980_RS23560	COG0174	glutamine synthetase
CP980_RS23580	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CP980_RS23615	COG1228	amidohydrolase
CP980_RS23630	COG1609	Transcriptional regulator
CP980_RS23635	COG0366	Alpha amylase catalytic
CP980_RS23645	COG1175	transmembrane transport
CP980_RS23650	COG3833	ABC-type maltose transport systems, permease component
CP980_RS23655	COG0366	Alpha amylase catalytic
CP980_RS23720	COG2365	Tyrosine phosphatase family
CP980_RS23740	COG0745	RESPONSE REGULATOR receiver
CP980_RS23800	COG0321	lipoyl(octanoyl) transferase activity
CP980_RS23805	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CP980_RS23835	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS23845	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP980_RS23860	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP980_RS23865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP980_RS23870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CP980_RS23910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP980_RS23910	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP980_RS23915	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP980_RS23930	COG2226	methyltransferase
CP980_RS23955	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CP980_RS23960	COG2197	response regulator
CP980_RS23965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP980_RS23970	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CP980_RS23990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP980_RS24000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CP980_RS24005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP980_RS24015	COG1376	ErfK ybiS ycfS ynhG family protein
CP980_RS24025	COG1845	cytochrome c oxidase, subunit III
CP980_RS24030	COG2010	Cytochrome c
CP980_RS24035	COG0723	plastoquinol--plastocyanin reductase activity
CP980_RS24040	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP980_RS24045	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP980_RS24050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP980_RS24075	COG0791	NLP P60 protein
CP980_RS24090	COG0438	transferase activity, transferring glycosyl groups
CP980_RS24125	COG0003	Pfam Anion-transporting ATPase
CP980_RS24135	COG1940	carbohydrate kinase activity
CP980_RS24160	COG4585	Histidine kinase
CP980_RS24165	COG2197	response regulator
CP980_RS24170	COG0205	6-phosphofructokinase activity
CP980_RS24185	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP980_RS24195	COG2193	ferroxidase activity
CP980_RS24200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP980_RS24210	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CP980_RS24215	COG2815	serine threonine protein kinase
CP980_RS24215	COG0515	serine threonine protein kinase
CP980_RS24220	COG2022	thiamine diphosphate biosynthetic process
CP980_RS24230	COG2022	thiamine diphosphate biosynthetic process
CP980_RS24230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP980_RS24235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP980_RS24245	COG0352	thiamine-phosphate diphosphorylase activity
CP980_RS24260	COG1233	COG1233 Phytoene dehydrogenase and related
CP980_RS24275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP980_RS24285	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CP980_RS24295	COG1309	transcriptional regulator
CP980_RS24310	COG0714	Associated with various cellular activities
CP980_RS24320	COG0275	rRNA processing
CP980_RS24335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP980_RS24345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP980_RS24350	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP980_RS24360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP980_RS24365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CP980_RS24390	COG1799	cell septum assembly
CP980_RS24405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CP980_RS24415	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CP980_RS24435	COG1088	dTDP-glucose 4,6-dehydratase activity
CP980_RS24440	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP980_RS24450	COG2205	protein histidine kinase activity
CP980_RS24490	COG0587	DNA-directed DNA polymerase activity
CP980_RS24495	COG1432	Conserved Protein
CP980_RS24515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CP980_RS24530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CP980_RS24535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP980_RS24540	COG0131	Imidazoleglycerol-phosphate dehydratase
CP980_RS24545	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CP980_RS24550	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CP980_RS24555	COG0251	oxidation-reduction process
CP980_RS24560	COG0107	imidazoleglycerol-phosphate synthase activity
CP980_RS24570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CP980_RS24595	COG0134	indole-3-glycerol-phosphate synthase activity
CP980_RS24605	COG0133	tryptophan synthase activity
CP980_RS24610	COG0159	tryptophan synthase activity
CP980_RS24620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CP980_RS24625	COG2301	Belongs to the HpcH HpaI aldolase family
CP980_RS24630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP980_RS24635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP980_RS24665	COG0070	glutamate synthase
CP980_RS24665	COG0069	glutamate synthase activity
CP980_RS24665	COG0067	glutamate synthase
CP980_RS24705	COG2304	oxidoreductase activity
CP980_RS24720	COG0657	acetylesterase activity
CP980_RS24740	COG1960	acyl-CoA dehydrogenase activity
CP980_RS24745	COG1960	acyl-CoA dehydrogenase activity
CP980_RS24750	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS24755	COG1309	transcriptional regulator
CP980_RS24760	COG0183	Belongs to the thiolase family
CP980_RS24765	COG1278	Cold shock
CP980_RS24775	COG2365	Tyrosine phosphatase family
CP980_RS24795	COG1024	Enoyl-CoA hydratase
CP980_RS24805	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS24820	COG2197	response regulator
CP980_RS24830	COG0287	Prephenate dehydrogenase
CP980_RS24830	COG1605	Chorismate mutase
CP980_RS24855	COG0737	Belongs to the 5'-nucleotidase family
CP980_RS24910	COG0559	Belongs to the binding-protein-dependent transport system permease family
CP980_RS24925	COG2050	protein possibly involved in aromatic compounds catabolism
CP980_RS24960	COG1643	Atp-dependent helicase
CP980_RS24965	COG2226	methyltransferase
CP980_RS24980	COG0237	dephospho-CoA kinase activity
CP980_RS25000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP980_RS25050	COG2313	pseudouridylate synthase activity
CP980_RS25065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP980_RS25070	COG0584	glycerophosphoryl diester phosphodiesterase
CP980_RS25075	COG0556	nucleotide-excision repair
CP980_RS25095	COG0477	Major facilitator Superfamily
CP980_RS25100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP980_RS25110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP980_RS25150	COG0322	excinuclease ABC activity
CP980_RS25155	COG1660	Displays ATPase and GTPase activities
CP980_RS25165	COG1481	regulation of sporulation
CP980_RS25175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP980_RS25180	COG0126	phosphoglycerate kinase activity
CP980_RS25185	COG0149	triose-phosphate isomerase activity
CP980_RS25190	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP980_RS25200	COG0166	Belongs to the GPI family
CP980_RS25205	COG0363	glucosamine-6-phosphate deaminase activity
CP980_RS25220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP980_RS25230	COG0109	protoheme IX farnesyltransferase activity
CP980_RS25245	COG1612	heme a metabolic process
CP980_RS25275	COG0719	Fe-S assembly protein
CP980_RS25285	COG0396	ATPase activity
CP980_RS25290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP980_RS25295	COG0822	iron-sulfur transferase activity
CP980_RS25300	COG2151	metal-sulfur cluster biosynthetic enzyme
CP980_RS25320	COG2171	N-acyltransferase activity
CP980_RS25375	COG4585	Histidine kinase
CP980_RS25380	COG2197	response regulator
CP980_RS25385	COG0768	penicillin binding
CP980_RS25400	COG1104	cysteine desulfurase activity
CP980_RS25430	COG1797	cobyrinic acid a,c-diamide synthase activity
CP980_RS25445	COG1492	cobalamin metabolic process
CP980_RS25485	COG0488	(ABC) transporter
CP980_RS25500	COG1302	Protein conserved in bacteria
CP980_RS25525	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS25540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP980_RS25600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP980_RS25605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP980_RS25625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CP980_RS25640	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS25645	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CP980_RS25655	COG2186	Transcriptional regulator
CP980_RS25675	COG0560	Phosphoserine phosphatase
CP980_RS25675	COG3830	Belongs to the UPF0237 family
CP980_RS25685	COG1716	ATPase activity
CP980_RS25685	COG0842	Transport permease protein
CP980_RS25685	COG1131	(ABC) transporter
CP980_RS25695	COG4585	Histidine kinase
CP980_RS25700	COG2197	response regulator
CP980_RS25715	COG1119	ATPase activity
CP980_RS25740	COG1881	PFAM PEBP family protein
CP980_RS25750	COG2094	Belongs to the DNA glycosylase MPG family
CP980_RS25785	COG0647	UMP catabolic process
CP980_RS25790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP980_RS25795	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP980_RS25800	COG1120	ATPase activity
CP980_RS25820	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP980_RS25825	COG0497	DNA recombination
CP980_RS25830	COG0297	glycogen (starch) synthase activity
CP980_RS25840	COG0277	FAD linked oxidase domain protein
CP980_RS25845	COG3387	PFAM Glycoside hydrolase 15-related
CP980_RS25850	COG0504	CTP synthase activity
CP980_RS25855	COG0494	nUDIX hydrolase
CP980_RS25865	COG0686	Belongs to the AlaDH PNT family
CP980_RS25880	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CP980_RS25885	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CP980_RS25890	COG1187	pseudouridine synthase activity
CP980_RS25940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CP980_RS25950	COG1160	GTP binding
CP980_RS25965	COG3583	domain protein
CP980_RS25975	COG0671	phosphoesterase, PA-phosphatase related
CP980_RS25985	COG0477	Major facilitator Superfamily
CP980_RS25990	COG1960	acyl-CoA dehydrogenase activity
CP980_RS25995	COG1799	cell septum assembly
CP980_RS26045	COG0587	DNA-directed DNA polymerase activity
CP980_RS26055	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CP980_RS26075	COG1725	Transcriptional regulator
CP980_RS26080	COG4044	May play a role in the intracellular transport of hydrophobic ligands
CP980_RS26090	COG2755	lipolytic protein G-D-S-L family
CP980_RS26105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP980_RS26115	COG2188	Transcriptional regulator
CP980_RS26120	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CP980_RS26145	COG0243	molybdopterin cofactor binding
CP980_RS26150	COG2851	Citrate transporter
CP980_RS26170	COG1960	acyl-CoA dehydrogenase activity
CP980_RS26210	COG3876	Protein conserved in bacteria
CP980_RS26220	COG0318	PFAM AMP-dependent synthetase and ligase
CP980_RS26235	COG1960	acyl-CoA dehydrogenase activity
CP980_RS26260	COG2149	membrane
CP980_RS26265	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP980_RS26290	COG1113	amino acid transport
CP980_RS26300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP980_RS26335	COG0667	Aldo Keto reductase
CP980_RS26340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP980_RS26350	COG0598	Magnesium transport protein CorA
CP980_RS26370	COG0215	cysteine-tRNA ligase activity
CP980_RS26380	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP980_RS26385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP980_RS26390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP980_RS26395	COG1414	Transcriptional regulator
CP980_RS26400	COG0646	methionine synthase
CP980_RS26400	COG1410	methionine synthase
CP980_RS26415	COG4166	transmembrane transport
CP980_RS26420	COG2197	response regulator
CP980_RS26430	COG0517	IMP dehydrogenase activity
CP980_RS26430	COG1994	Peptidase M50
CP980_RS26455	COG1222	aaa ATPase
CP980_RS26460	COG4122	O-methyltransferase activity
CP980_RS26475	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP980_RS26480	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP980_RS26485	COG1609	Transcriptional regulator
CP980_RS26495	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP980_RS26530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP980_RS26535	COG0805	protein transport
CP980_RS26550	COG0564	pseudouridine synthase activity
CP980_RS26565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP980_RS26575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP980_RS26590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP980_RS26595	COG1113	amino acid transport
CP980_RS26605	COG0174	glutamine synthetase
CP980_RS26610	COG1012	belongs to the aldehyde dehydrogenase family
CP980_RS26615	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS26655	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CP980_RS26660	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CP980_RS26665	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CP980_RS26670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP980_RS26675	COG5002	protein histidine kinase activity
CP980_RS26680	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CP980_RS26685	COG0072	phenylalanine-tRNA ligase activity
CP980_RS26685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP980_RS26710	COG1649	PFAM Uncharacterised BCR, COG1649
CP980_RS26720	COG0697	spore germination
CP980_RS26760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP980_RS26765	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CP980_RS26770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CP980_RS26775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP980_RS26780	COG1438	arginine binding
CP980_RS26805	COG0137	argininosuccinate synthase activity
CP980_RS26810	COG0165	Argininosuccinate lyase
CP980_RS26825	COG0477	Major facilitator Superfamily
CP980_RS26835	COG0318	PFAM AMP-dependent synthetase and ligase
CP980_RS26835	COG0204	Acyl-transferase
CP980_RS26840	COG0584	glycerophosphoryl diester phosphodiesterase
CP980_RS26870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP980_RS26875	COG2011	ABC-type metal ion transport system permease component
CP980_RS26880	COG1464	Belongs to the NlpA lipoprotein family
CP980_RS26895	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP980_RS26900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP980_RS26900	COG1648	precorrin-2 dehydrogenase activity
CP980_RS26955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP980_RS26965	COG0454	-acetyltransferase
CP980_RS26965	COG0456	acetyltransferase
CP980_RS27020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP980_RS27045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CP980_RS27050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP980_RS27070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP980_RS27075	COG1560	Kdo2-lipid A biosynthetic process
CP980_RS27080	COG0438	transferase activity, transferring glycosyl groups
CP980_RS27090	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CP980_RS27095	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CP980_RS27100	COG0217	transcriptional regulatory protein
CP980_RS27105	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CP980_RS27110	COG0632	four-way junction helicase activity
CP980_RS27115	COG2255	four-way junction helicase activity
CP980_RS27125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP980_RS27130	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP980_RS27135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CP980_RS27140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP980_RS27145	COG1196	nuclear chromosome segregation
CP980_RS27150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP980_RS27160	COG0124	histidyl-tRNA synthetase
CP980_RS27165	COG2197	response regulator
CP980_RS27170	COG4585	Histidine kinase
CP980_RS27180	COG1131	(ABC) transporter
CP980_RS27200	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CP980_RS27215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP980_RS27220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CP980_RS27225	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CP980_RS27230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP980_RS27235	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP980_RS27240	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP980_RS27245	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CP980_RS27250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CP980_RS27265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP980_RS27270	COG0006	proline dipeptidase activity
CP980_RS27275	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CP980_RS27280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CP980_RS27290	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CP980_RS27295	COG0540	Belongs to the ATCase OTCase family
CP980_RS27300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP980_RS27310	COG0505	Belongs to the CarA family
CP980_RS27315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP980_RS27320	COG0167	dihydroorotate dehydrogenase activity
CP980_RS27325	COG0284	orotidine-5'-phosphate decarboxylase activity
CP980_RS27335	COG0194	GDP metabolic process
CP980_RS27350	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CP980_RS27365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP980_RS27375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CP980_RS27380	COG2390	Transcriptional regulator
CP980_RS27410	COG0492	ferredoxin-NADP+ reductase activity
CP980_RS27425	COG0028	Belongs to the TPP enzyme family
CP980_RS27450	COG0693	protein deglycase activity
CP980_RS27465	COG1366	Belongs to the anti-sigma-factor antagonist family
CP980_RS27485	COG2208	phosphoserine phosphatase activity
CP980_RS27485	COG2770	Histidine kinase
CP980_RS27490	COG0489	protein tyrosine kinase activity
CP980_RS27500	COG1012	belongs to the aldehyde dehydrogenase family
CP980_RS27540	COG3548	integral membrane protein
CP980_RS27570	COG3275	phosphorelay sensor kinase activity
CP980_RS27575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP980_RS27605	COG0531	amino acid
CP980_RS27620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP980_RS27620	COG0456	acetyltransferase
CP980_RS27625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP980_RS27640	COG2233	PERMEase
CP980_RS27645	COG0738	Major facilitator superfamily
CP980_RS27650	COG1846	Transcriptional regulator
CP980_RS27650	COG1940	carbohydrate kinase activity
CP980_RS27655	COG0598	Magnesium transport protein CorA
CP980_RS27665	COG1595	DNA-templated transcription, initiation
CP980_RS27685	COG3201	nicotinamide mononucleotide transporter
CP980_RS27690	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP980_RS27690	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP980_RS27695	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CP980_RS27700	COG0140	phosphoribosyl-ATP diphosphatase activity
CP980_RS27705	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CP980_RS27760	COG1309	transcriptional regulator
CP980_RS27765	COG1960	acyl-CoA dehydrogenase activity
CP980_RS27805	COG0463	Glycosyl transferase, family 2
CP980_RS27865	COG1984	allophanate hydrolase subunit 2
CP980_RS27870	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CP980_RS27875	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CP980_RS27905	COG2018	Roadblock/LC7 domain
CP980_RS27920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP980_RS27945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP980_RS27955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP980_RS27990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP980_RS28010	COG1716	ATPase activity
CP980_RS28030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP980_RS28040	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP980_RS28040	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP980_RS28070	COG1695	Transcriptional regulator
CP980_RS28085	COG0697	spore germination
CP980_RS28100	COG0697	spore germination
CP980_RS28105	COG0583	DNA-binding transcription factor activity
CP980_RS28140	COG0747	negative chemotaxis
CP980_RS28145	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP980_RS28160	COG2318	DinB family
CP980_RS28165	COG0673	inositol 2-dehydrogenase activity
CP980_RS28170	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CP980_RS28185	COG1968	undecaprenyl-diphosphatase activity
CP980_RS28200	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP980_RS28245	COG0110	maltose O-acetyltransferase activity
CP980_RS28255	COG1832	CoA-binding protein
CP980_RS28260	COG1739	Uncharacterized protein family UPF0029
CP980_RS28265	COG0420	3'-5' exonuclease activity
CP980_RS28270	COG0419	ATPase involved in DNA repair
CP980_RS28285	COG1522	sequence-specific DNA binding
CP980_RS28310	COG2267	carboxylic ester hydrolase activity
CP980_RS28315	COG2188	Transcriptional regulator
CP980_RS28320	COG1940	carbohydrate kinase activity
CP980_RS28325	COG2197	response regulator
CP980_RS28355	COG1819	glycosyl
CP980_RS28360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP980_RS28365	COG0318	PFAM AMP-dependent synthetase and ligase
CP980_RS28370	COG3903	Transcriptional regulator
CP980_RS28370	COG3629	intracellular signal transduction
CP980_RS28380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP980_RS28400	COG1024	Enoyl-CoA hydratase
CP980_RS28415	COG0604	alcohol dehydrogenase
CP980_RS28420	COG3251	PFAM MbtH domain protein
CP980_RS28425	COG0475	glutathione-regulated potassium exporter activity
CP980_RS28440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP980_RS28450	COG0142	geranyltranstransferase activity
CP980_RS28490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP980_RS28515	COG2226	methyltransferase
CP980_RS28525	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CP980_RS28530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP980_RS28535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CP980_RS28540	COG0156	8-amino-7-oxononanoate synthase activity
CP980_RS28565	COG0831	urea catabolic process
CP980_RS28570	COG0832	Belongs to the urease beta subunit family
CP980_RS28575	COG0804	urea catabolic process
CP980_RS28580	COG0830	nickel cation binding
CP980_RS28585	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP980_RS28590	COG0829	nickel cation binding
CP980_RS28600	COG0204	Acyl-transferase
CP980_RS28610	COG0205	6-phosphofructokinase activity
CP980_RS28615	COG3442	glutamine amidotransferase
CP980_RS28625	COG0242	peptide deformylase activity
CP980_RS28635	COG1960	acyl-CoA dehydrogenase activity
CP980_RS28660	COG4733	cellulase activity
CP980_RS28660	COG5297	Belongs to the glycosyl hydrolase family 6
CP980_RS28670	COG0601	transmembrane transport
CP980_RS28675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP980_RS28685	COG1124	(ABC) transporter
CP980_RS28705	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP980_RS28710	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP980_RS28740	COG2197	response regulator
CP980_RS28800	COG1012	belongs to the aldehyde dehydrogenase family
CP980_RS28810	COG0517	IMP dehydrogenase activity
CP980_RS28810	COG4175	Glycine betaine
CP980_RS28815	COG4176	ABC-type proline glycine betaine transport system permease component
CP980_RS28825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP980_RS28830	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CP980_RS28835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP980_RS28855	COG0189	ligase activity
CP980_RS28865	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CP980_RS28890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP980_RS28900	COG2175	clavaminate synthase activity
CP980_RS28905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP980_RS28915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP980_RS28930	COG0367	asparagine synthase
CP980_RS28955	COG1012	belongs to the aldehyde dehydrogenase family
CP980_RS29015	COG2018	Roadblock/LC7 domain
CP980_RS29025	COG3012	SEC-C Motif Domain Protein
CP980_RS29030	COG1946	Acyl-CoA thioesterase
CP980_RS29045	COG1132	(ABC) transporter
CP980_RS29050	COG1132	(ABC) transporter
CP980_RS29065	COG1132	(ABC) transporter
CP980_RS29075	COG2072	flavoprotein involved in K transport
CP980_RS29080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP980_RS29090	COG0702	epimerase
CP980_RS29110	COG0406	alpha-ribazole phosphatase activity
CP980_RS29120	COG4106	trans-aconitate 2-methyltransferase activity
CP980_RS29130	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CP980_RS29135	COG2706	6-phosphogluconolactonase activity
CP980_RS29145	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP980_RS29160	COG1902	pentaerythritol trinitrate reductase activity
CP980_RS29165	COG0640	Transcriptional regulator
CP980_RS29170	COG0493	'glutamate synthase
CP980_RS29185	COG1309	transcriptional regulator
CP980_RS29205	COG0584	glycerophosphoryl diester phosphodiesterase
CP980_RS29215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP980_RS29265	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP980_RS29285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP980_RS29295	COG0644	oxidoreductase
CP980_RS29335	COG1940	carbohydrate kinase activity
CP980_RS29360	COG0464	growth
CP980_RS29385	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CP980_RS29435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP980_RS29455	COG0494	nUDIX hydrolase
CP980_RS29465	COG0842	Transport permease protein
CP980_RS29465	COG1131	(ABC) transporter
CP980_RS29465	COG1716	ATPase activity
CP980_RS29515	COG0725	ABC transporter, periplasmic molybdate-binding protein
CP980_RS29520	COG3585	molybdate ion transport
CP980_RS29535	COG1461	Dihydroxyacetone kinase
CP980_RS29540	COG2376	Dihydroxyacetone kinase
CP980_RS29545	COG3387	PFAM Glycoside hydrolase 15-related
CP980_RS29575	COG1271	oxidase subunit
CP980_RS29585	COG2017	converts alpha-aldose to the beta-anomer
CP980_RS29615	COG2259	Doxx family
CP980_RS29620	COG3387	PFAM Glycoside hydrolase 15-related
CP980_RS29640	COG0477	Major facilitator Superfamily
CP980_RS29660	COG1063	alcohol dehydrogenase
CP980_RS29665	COG0156	8-amino-7-oxononanoate synthase activity
CP980_RS29675	COG1349	DNA-binding transcription factor activity
CP980_RS29695	COG1960	acyl-CoA dehydrogenase activity
CP980_RS29715	COG0444	Belongs to the ABC transporter superfamily
CP980_RS29720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP980_RS29730	COG0747	negative chemotaxis
CP980_RS29735	COG2957	Belongs to the agmatine deiminase family
CP980_RS29745	COG0804	urea catabolic process
CP980_RS29750	COG0832	Belongs to the urease beta subunit family
CP980_RS29750	COG0831	urea catabolic process
CP980_RS29760	COG1309	transcriptional regulator
CP980_RS29765	COG2957	Belongs to the agmatine deiminase family
CP980_RS29780	COG2815	serine threonine protein kinase
CP980_RS29780	COG0515	serine threonine protein kinase
CP980_RS29805	COG2070	2-Nitropropane dioxygenase
CP980_RS29815	COG0387	Pfam Sodium calcium exchanger
CP980_RS29820	COG2366	antibiotic biosynthetic process
CP980_RS29825	COG0318	PFAM AMP-dependent synthetase and ligase
CP980_RS29840	COG2267	carboxylic ester hydrolase activity
CP980_RS29850	COG1024	Enoyl-CoA hydratase
CP980_RS29885	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP980_RS29885	COG1672	PFAM Archaeal ATPase
CP980_RS29900	COG1053	succinate dehydrogenase
CP980_RS29925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP980_RS29925	COG2010	Cytochrome c
CP980_RS29930	COG2080	2 iron, 2 sulfur cluster binding
CP980_RS29940	COG0531	amino acid
CP980_RS29980	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP980_RS29990	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP980_RS30070	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS30090	COG0583	DNA-binding transcription factor activity
CP980_RS30095	COG1846	Transcriptional regulator
CP980_RS30095	COG1940	carbohydrate kinase activity
CP980_RS30105	COG1175	transmembrane transport
CP980_RS30115	COG2723	6-phospho-beta-galactosidase activity
CP980_RS30200	COG0513	Belongs to the DEAD box helicase family
CP980_RS30205	COG1846	Transcriptional regulator
CP980_RS30215	COG1278	Cold shock
CP980_RS30240	COG2124	cytochrome p450
CP980_RS30255	COG2837	iron assimilation
CP980_RS30275	COG4941	Belongs to the sigma-70 factor family
CP980_RS30285	COG1136	(ABC) transporter
CP980_RS30300	COG1136	(ABC) transporter
CP980_RS30300	COG4591	ABC-type transport system involved in lipoprotein release permease component
CP980_RS30305	COG2188	Transcriptional regulator
CP980_RS30325	COG3842	ATPase activity
CP980_RS30345	COG2226	methyltransferase
CP980_RS30350	COG2272	Belongs to the type-B carboxylesterase lipase family
CP980_RS30355	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CP980_RS30375	COG1609	Transcriptional regulator
CP980_RS30390	COG0657	acetylesterase activity
CP980_RS30410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP980_RS30420	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP980_RS30425	COG3473	Maleate cis-trans isomerase
CP980_RS30475	COG1404	Belongs to the peptidase S8 family
CP980_RS30530	COG1834	amidinotransferase
CP980_RS30550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CP980_RS30550	COG0473	3-isopropylmalate dehydrogenase activity
CP980_RS30565	COG0318	PFAM AMP-dependent synthetase and ligase
CP980_RS30585	COG0583	DNA-binding transcription factor activity
CP980_RS30605	COG0745	RESPONSE REGULATOR receiver
CP980_RS30700	COG0477	Major facilitator Superfamily
CP980_RS30715	COG1960	acyl-CoA dehydrogenase activity
CP980_RS30720	COG1309	transcriptional regulator
CP980_RS30725	COG0667	Aldo Keto reductase
CP980_RS30760	COG1505	serine-type exopeptidase activity
CP980_RS30800	COG1132	(ABC) transporter
CP980_RS30820	COG1796	DNA polymerase
CP980_RS30820	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP980_RS30875	COG0596	Alpha beta hydrolase
CP980_RS30920	COG4257	antibiotic catabolic process
CP980_RS30955	COG0702	epimerase
CP980_RS30960	COG1733	regulation of RNA biosynthetic process
CP980_RS30975	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CP980_RS30980	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CP980_RS30985	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CP980_RS31040	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS31065	COG1088	dTDP-glucose 4,6-dehydratase activity
CP980_RS31115	COG0463	Glycosyl transferase, family 2
CP980_RS31170	COG0714	Associated with various cellular activities
CP980_RS31180	COG0586	Pfam SNARE associated Golgi protein
CP980_RS31185	COG0671	phosphoesterase, PA-phosphatase related
CP980_RS31220	COG4989	oxidoreductase activity
CP980_RS31235	COG2815	serine threonine protein kinase
CP980_RS31235	COG0515	serine threonine protein kinase
CP980_RS31285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP980_RS31300	COG2409	Drug exporters of the RND superfamily
CP980_RS31310	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS31330	COG1957	nucleoside hydrolase
CP980_RS31335	COG0328	RNA-DNA hybrid ribonuclease activity
CP980_RS31355	COG0137	argininosuccinate synthase activity
CP980_RS31365	COG0596	Alpha beta hydrolase
CP980_RS31460	COG4213	ABC transporter substrate-binding protein
CP980_RS31465	COG2205	protein histidine kinase activity
CP980_RS31470	COG0745	RESPONSE REGULATOR receiver
CP980_RS31480	COG0577	efflux transmembrane transporter activity
CP980_RS31480	COG1136	(ABC) transporter
CP980_RS31485	COG0577	efflux transmembrane transporter activity
CP980_RS31485	COG1136	(ABC) transporter
CP980_RS31580	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP980_RS31580	COG0596	Alpha beta hydrolase
CP980_RS31595	COG0318	PFAM AMP-dependent synthetase and ligase
CP980_RS31630	COG3511	phospholipase C
CP980_RS31665	COG4585	Histidine kinase
CP980_RS31670	COG2197	response regulator
CP980_RS31685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP980_RS31700	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CP980_RS31705	COG1472	Belongs to the glycosyl hydrolase 3 family
CP980_RS31710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP980_RS31735	COG1404	Belongs to the peptidase S8 family
CP980_RS31740	COG0477	Major facilitator Superfamily
CP980_RS31805	COG2197	response regulator
CP980_RS31810	COG4585	Histidine kinase
CP980_RS31815	COG2409	Drug exporters of the RND superfamily
CP980_RS31820	COG2378	regulation of single-species biofilm formation
CP980_RS31825	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS31840	COG3848	Pyruvate phosphate dikinase
CP980_RS31840	COG0574	Belongs to the PEP-utilizing enzyme family
CP980_RS31850	COG0477	Major facilitator Superfamily
CP980_RS31860	COG4221	oxidoreductase activity
CP980_RS31865	COG1428	Deoxynucleoside kinase
CP980_RS31890	COG0583	DNA-binding transcription factor activity
CP980_RS31930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP980_RS31935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP980_RS31945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP980_RS31950	COG0456	acetyltransferase
CP980_RS31955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP980_RS31960	COG1126	abc transporter atp-binding protein
CP980_RS31965	COG0765	amino acid transport
CP980_RS31990	COG1917	Cupin 2, conserved barrel domain protein
CP980_RS31990	COG1396	sequence-specific DNA binding
CP980_RS32060	COG1309	transcriptional regulator
CP980_RS32115	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS32130	COG4585	Histidine kinase
CP980_RS32135	COG2197	response regulator
CP980_RS32140	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS32175	COG1846	Transcriptional regulator
CP980_RS32180	COG1073	alpha beta
CP980_RS32185	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP980_RS32190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP980_RS32195	COG1116	anion transmembrane transporter activity
CP980_RS32215	COG0745	RESPONSE REGULATOR receiver
CP980_RS32240	COG0765	amino acid transport
CP980_RS32250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP980_RS32255	COG1126	abc transporter atp-binding protein
CP980_RS32265	COG3119	arylsulfatase activity
CP980_RS32295	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP980_RS32320	COG0028	Belongs to the TPP enzyme family
CP980_RS32325	COG0069	glutamate synthase activity
CP980_RS32330	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS32345	COG1295	ribonuclease BN
CP980_RS32355	COG2890	protein-(glutamine-N5) methyltransferase activity
CP980_RS32390	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP980_RS32400	COG3903	Transcriptional regulator
CP980_RS32400	COG3629	intracellular signal transduction
CP980_RS32420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP980_RS32455	COG4977	sequence-specific DNA binding
CP980_RS32465	COG1309	transcriptional regulator
CP980_RS32470	COG0604	alcohol dehydrogenase
CP980_RS32500	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CP980_RS32530	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CP980_RS32565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP980_RS32575	COG0784	Response regulator, receiver
CP980_RS32610	COG2080	2 iron, 2 sulfur cluster binding
CP980_RS32615	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CP980_RS32650	COG2770	Histidine kinase
CP980_RS32650	COG2208	phosphoserine phosphatase activity
CP980_RS32655	COG0596	Alpha beta hydrolase
CP980_RS32670	COG4106	trans-aconitate 2-methyltransferase activity
CP980_RS32680	COG0473	3-isopropylmalate dehydrogenase activity
CP980_RS32685	COG1278	Cold shock
CP980_RS32690	COG0513	Belongs to the DEAD box helicase family
CP980_RS32820	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP980_RS32855	COG2814	Major facilitator Superfamily
CP980_RS32860	COG1595	DNA-templated transcription, initiation
CP980_RS32870	COG0402	S-adenosylhomocysteine deaminase activity
CP980_RS32895	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP980_RS32895	COG5479	isomerase activity
CP980_RS32905	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CP980_RS32930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CP980_RS32945	COG1968	undecaprenyl-diphosphatase activity
CP980_RS32955	COG0640	Transcriptional regulator
CP980_RS32975	COG0531	amino acid
CP980_RS32990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP980_RS33015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP980_RS33025	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CP980_RS33030	COG1846	Transcriptional regulator
CP980_RS33035	COG2409	Drug exporters of the RND superfamily
CP980_RS33040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CP980_RS33045	COG2770	Histidine kinase
CP980_RS33045	COG2208	phosphoserine phosphatase activity
CP980_RS33120	COG0667	Aldo Keto reductase
CP980_RS33160	COG0671	phosphoesterase, PA-phosphatase related
CP980_RS33165	COG0671	phosphoesterase, PA-phosphatase related
CP980_RS33170	COG0586	Pfam SNARE associated Golgi protein
CP980_RS33175	COG2376	Dihydroxyacetone kinase
CP980_RS33180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP980_RS33185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP980_RS33250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP980_RS33260	COG0640	Transcriptional regulator
CP980_RS33290	COG0483	inositol monophosphate 1-phosphatase activity
CP980_RS33305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP980_RS33325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP980_RS33345	COG3959	Transketolase, thiamine diphosphate binding domain
CP980_RS33350	COG3958	Transketolase
CP980_RS33365	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CP980_RS33380	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP980_RS33390	COG1960	acyl-CoA dehydrogenase activity
CP980_RS33400	COG2226	methyltransferase
CP980_RS33405	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS33415	COG2091	lysine biosynthetic process via aminoadipic acid
CP980_RS33420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP980_RS33425	COG2226	methyltransferase
CP980_RS33430	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CP980_RS33545	COG1846	Transcriptional regulator
CP980_RS33585	COG4977	sequence-specific DNA binding
CP980_RS33590	COG0662	Cupin 2, conserved barrel domain protein
CP980_RS33670	COG1278	Cold shock
CP980_RS33685	COG4977	sequence-specific DNA binding
CP980_RS33705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CP980_RS33760	COG2226	methyltransferase
CP980_RS33765	COG2318	DinB family
CP980_RS33795	COG1796	DNA polymerase
CP980_RS33795	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP980_RS33800	COG1028	Short-chain dehydrogenase reductase Sdr
CP980_RS33815	COG1335	isochorismatase
CP980_RS33900	COG1733	regulation of RNA biosynthetic process
CP980_RS33930	COG0740	serine-type endopeptidase activity
CP980_RS33935	COG0740	serine-type endopeptidase activity
CP980_RS33950	COG0488	(ABC) transporter
CP980_RS33970	COG1819	glycosyl
CP980_RS33995	COG1902	pentaerythritol trinitrate reductase activity
CP980_RS34125	COG3188	usher protein
CP980_RS34165	COG1278	Cold shock
CP980_RS34185	COG1404	Belongs to the peptidase S8 family
CP980_RS34260	COG2815	serine threonine protein kinase
CP980_RS34260	COG0515	serine threonine protein kinase
CP980_RS34350	COG5634	Uncharacterized conserved protein (DUF2278)
CP980_RS34390	COG0523	cobalamin synthesis protein
CP980_RS34405	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP980_RS34410	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP980_RS34415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP980_RS34420	COG0254	rRNA binding
CP980_RS34430	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP980_RS34505	COG0300	oxidoreductase activity
CP980_RS34530	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP980_RS34575	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CP980_RS34575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP980_RS34780	COG2197	response regulator
CP980_RS34805	COG4585	Histidine kinase
CP980_RS34810	COG2362	D-Aminopeptidase
CP980_RS34825	COG0189	ligase activity
CP980_RS34845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP980_RS34915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP980_RS34925	COG1278	Cold shock