locus-tag	class	description
B1H20_RS00115	COG1132	(ABC) transporter
B1H20_RS00170	COG2197	response regulator
B1H20_RS00200	COG0583	DNA-binding transcription factor activity
B1H20_RS00215	COG0590	tRNA wobble adenosine to inosine editing
B1H20_RS00230	COG3848	Pyruvate phosphate dikinase
B1H20_RS00230	COG0574	Belongs to the PEP-utilizing enzyme family
B1H20_RS00255	COG4977	sequence-specific DNA binding
B1H20_RS00275	COG4941	Belongs to the sigma-70 factor family
B1H20_RS00285	COG5297	Belongs to the glycosyl hydrolase family 6
B1H20_RS00330	COG0477	Major facilitator Superfamily
B1H20_RS00340	COG1846	Transcriptional regulator
B1H20_RS00345	COG1764	response to oxidative stress
B1H20_RS00355	COG0789	Transcriptional regulator
B1H20_RS00380	COG1902	pentaerythritol trinitrate reductase activity
B1H20_RS00385	COG0640	Transcriptional regulator
B1H20_RS00390	COG1064	alcohol dehydrogenase
B1H20_RS00405	COG0702	epimerase
B1H20_RS00420	COG0642	Histidine kinase
B1H20_RS00435	COG2318	DinB family
B1H20_RS00485	COG1349	DNA-binding transcription factor activity
B1H20_RS00520	COG0596	Alpha beta hydrolase
B1H20_RS00550	COG2318	DinB family
B1H20_RS00575	COG0254	rRNA binding
B1H20_RS00580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B1H20_RS00630	COG1024	Enoyl-CoA hydratase
B1H20_RS00650	COG1132	(ABC) transporter
B1H20_RS00655	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1H20_RS00675	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B1H20_RS00705	COG2070	2-Nitropropane dioxygenase
B1H20_RS00710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B1H20_RS00720	COG0515	serine threonine protein kinase
B1H20_RS00725	COG0659	secondary active sulfate transmembrane transporter activity
B1H20_RS00730	COG0789	Transcriptional regulator
B1H20_RS00745	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS00750	COG2813	Specifically methylates the guanine in position
B1H20_RS00765	COG2356	endonuclease I
B1H20_RS00770	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
B1H20_RS00770	COG2066	Belongs to the glutaminase family
B1H20_RS00780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1H20_RS00785	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
B1H20_RS00800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B1H20_RS00805	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B1H20_RS00810	COG2080	2 iron, 2 sulfur cluster binding
B1H20_RS00855	COG2365	Tyrosine phosphatase family
B1H20_RS00890	COG1120	ATPase activity
B1H20_RS00895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B1H20_RS00915	COG0477	Major facilitator Superfamily
B1H20_RS00925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS00930	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS00935	COG1169	isochorismate synthase
B1H20_RS00940	COG1021	2,3-dihydroxybenzoate-AMP ligase
B1H20_RS00945	COG1535	isochorismatase
B1H20_RS00945	COG3433	isochorismatase activity
B1H20_RS00950	COG1535	isochorismatase
B1H20_RS00950	COG3433	isochorismatase activity
B1H20_RS00955	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B1H20_RS00975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B1H20_RS01010	COG3845	ABC transporter
B1H20_RS01030	COG0148	phosphopyruvate hydratase activity
B1H20_RS01050	COG2382	esterase
B1H20_RS01055	COG1132	(ABC) transporter
B1H20_RS01070	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B1H20_RS01075	COG1120	ATPase activity
B1H20_RS01080	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS01085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS01090	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B1H20_RS01105	COG5002	protein histidine kinase activity
B1H20_RS01110	COG0745	RESPONSE REGULATOR receiver
B1H20_RS01145	COG3559	Exporter of polyketide antibiotics
B1H20_RS01150	COG1131	(ABC) transporter
B1H20_RS01160	COG0587	DNA-directed DNA polymerase activity
B1H20_RS01235	COG1295	ribonuclease BN
B1H20_RS01310	COG4221	oxidoreductase activity
B1H20_RS01325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H20_RS01355	COG2376	Dihydroxyacetone kinase
B1H20_RS01360	COG1461	Dihydroxyacetone kinase
B1H20_RS01375	COG0488	(ABC) transporter
B1H20_RS01405	COG1191	sigma factor activity
B1H20_RS01410	COG1309	transcriptional regulator
B1H20_RS01415	COG3246	L-lysine catabolic process to acetate
B1H20_RS01420	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H20_RS01435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B1H20_RS01440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B1H20_RS01455	COG1120	ATPase activity
B1H20_RS01460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS01485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H20_RS01540	COG1959	2 iron, 2 sulfur cluster binding
B1H20_RS01540	COG1295	ribonuclease BN
B1H20_RS01570	COG1120	ATPase activity
B1H20_RS01575	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS01580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS01590	COG0789	Transcriptional regulator
B1H20_RS01615	COG1874	Beta-galactosidase
B1H20_RS01615	COG0366	Alpha amylase catalytic
B1H20_RS01630	COG1172	Belongs to the binding-protein-dependent transport system permease family
B1H20_RS01640	COG1129	ABC transporter
B1H20_RS01645	COG1879	ABC-type sugar transport system periplasmic component
B1H20_RS01695	COG0328	RNA-DNA hybrid ribonuclease activity
B1H20_RS01700	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS01705	COG1132	(ABC) transporter
B1H20_RS01835	COG5002	protein histidine kinase activity
B1H20_RS01865	COG0464	growth
B1H20_RS01875	COG1349	DNA-binding transcription factor activity
B1H20_RS01890	COG0702	epimerase
B1H20_RS01925	COG1940	carbohydrate kinase activity
B1H20_RS01930	COG2223	nitrite transmembrane transporter activity
B1H20_RS01950	COG0445	tRNA wobble uridine modification
B1H20_RS01960	COG0494	nUDIX hydrolase
B1H20_RS01990	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1H20_RS02040	COG0584	glycerophosphoryl diester phosphodiesterase
B1H20_RS02060	COG0671	phosphoesterase, PA-phosphatase related
B1H20_RS02100	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B1H20_RS02115	COG2706	6-phosphogluconolactonase activity
B1H20_RS02160	COG3961	Belongs to the TPP enzyme family
B1H20_RS02165	COG2197	response regulator
B1H20_RS02180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B1H20_RS02185	COG3483	tryptophan 2,3-dioxygenase activity
B1H20_RS02190	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B1H20_RS02210	COG0107	imidazoleglycerol-phosphate synthase activity
B1H20_RS02265	COG0515	serine threonine protein kinase
B1H20_RS02265	COG2815	serine threonine protein kinase
B1H20_RS02270	COG0667	Aldo Keto reductase
B1H20_RS02295	COG1253	flavin adenine dinucleotide binding
B1H20_RS02330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B1H20_RS02335	COG0531	amino acid
B1H20_RS02345	COG0174	glutamine synthetase
B1H20_RS02350	COG1012	belongs to the aldehyde dehydrogenase family
B1H20_RS02380	COG4981	capsule polysaccharide biosynthetic process
B1H20_RS02400	COG2835	tetraacyldisaccharide 4'-kinase activity
B1H20_RS02410	COG1802	Transcriptional regulator
B1H20_RS02415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B1H20_RS02420	COG0402	S-adenosylhomocysteine deaminase activity
B1H20_RS02440	COG0542	response to heat
B1H20_RS02495	COG1335	isochorismatase
B1H20_RS02510	COG2890	protein-(glutamine-N5) methyltransferase activity
B1H20_RS02520	COG4912	Dna alkylation repair
B1H20_RS02540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B1H20_RS02545	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B1H20_RS02550	COG2080	2 iron, 2 sulfur cluster binding
B1H20_RS02585	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B1H20_RS02595	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS02600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS02645	COG1891	lyase activity
B1H20_RS02660	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B1H20_RS02720	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
B1H20_RS02745	COG1309	transcriptional regulator
B1H20_RS02755	COG1982	Orn Lys Arg decarboxylase major
B1H20_RS02760	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS02775	COG1309	transcriptional regulator
B1H20_RS02820	COG0531	amino acid
B1H20_RS02830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H20_RS02840	COG2814	Major facilitator Superfamily
B1H20_RS02845	COG4221	oxidoreductase activity
B1H20_RS02860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1H20_RS02865	COG1116	anion transmembrane transporter activity
B1H20_RS02880	COG2072	flavoprotein involved in K transport
B1H20_RS02885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B1H20_RS02895	COG1132	(ABC) transporter
B1H20_RS02900	COG1846	Transcriptional regulator
B1H20_RS02910	COG0673	inositol 2-dehydrogenase activity
B1H20_RS02915	COG1132	(ABC) transporter
B1H20_RS02920	COG1132	(ABC) transporter
B1H20_RS02940	COG1793	dna ligase
B1H20_RS02955	COG1946	Acyl-CoA thioesterase
B1H20_RS02970	COG0386	Belongs to the glutathione peroxidase family
B1H20_RS02975	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS02985	COG0242	peptide deformylase activity
B1H20_RS02995	COG3442	glutamine amidotransferase
B1H20_RS03000	COG0205	6-phosphofructokinase activity
B1H20_RS03010	COG0204	Acyl-transferase
B1H20_RS03025	COG0829	nickel cation binding
B1H20_RS03030	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B1H20_RS03040	COG0804	urea catabolic process
B1H20_RS03045	COG0832	Belongs to the urease beta subunit family
B1H20_RS03050	COG0831	urea catabolic process
B1H20_RS03055	COG1309	transcriptional regulator
B1H20_RS03070	COG0740	serine-type endopeptidase activity
B1H20_RS03085	COG1280	lysine exporter protein (LysE YggA)
B1H20_RS03090	COG0583	DNA-binding transcription factor activity
B1H20_RS03110	COG0156	8-amino-7-oxononanoate synthase activity
B1H20_RS03115	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B1H20_RS03120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1H20_RS03125	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B1H20_RS03170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B1H20_RS03180	COG1940	carbohydrate kinase activity
B1H20_RS03185	COG2188	Transcriptional regulator
B1H20_RS03190	COG1595	DNA-templated transcription, initiation
B1H20_RS03205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1H20_RS03230	COG0626	cystathionine gamma-synthase activity
B1H20_RS03250	COG0419	ATPase involved in DNA repair
B1H20_RS03255	COG0420	3'-5' exonuclease activity
B1H20_RS03260	COG1739	Uncharacterized protein family UPF0029
B1H20_RS03265	COG1832	CoA-binding protein
B1H20_RS03305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B1H20_RS03325	COG1968	undecaprenyl-diphosphatase activity
B1H20_RS03340	COG0243	molybdopterin cofactor binding
B1H20_RS03350	COG2226	methyltransferase
B1H20_RS03355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1H20_RS03415	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B1H20_RS03485	COG0069	glutamate synthase activity
B1H20_RS03540	COG0477	Major facilitator Superfamily
B1H20_RS03550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B1H20_RS03560	COG0784	Response regulator, receiver
B1H20_RS03565	COG4251	negative regulation of phosphorylation
B1H20_RS03570	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1H20_RS03580	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B1H20_RS03590	COG1215	transferase activity, transferring glycosyl groups
B1H20_RS03610	COG3800	Transcriptional regulator
B1H20_RS03610	COG1396	sequence-specific DNA binding
B1H20_RS03710	COG1695	Transcriptional regulator
B1H20_RS03730	COG1595	DNA-templated transcription, initiation
B1H20_RS03785	COG0384	phenazine biosynthesis protein PhzF
B1H20_RS03815	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B1H20_RS03815	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B1H20_RS03825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B1H20_RS03845	COG1716	ATPase activity
B1H20_RS03865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B1H20_RS03900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B1H20_RS03910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1H20_RS03925	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
B1H20_RS03955	COG2018	Roadblock/LC7 domain
B1H20_RS04025	COG2364	Membrane
B1H20_RS04035	COG2270	Major facilitator Superfamily
B1H20_RS04050	COG1216	Glycosyl transferase, family 2
B1H20_RS04070	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS04075	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H20_RS04085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B1H20_RS04125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B1H20_RS04130	COG0140	phosphoribosyl-ATP diphosphatase activity
B1H20_RS04135	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B1H20_RS04140	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B1H20_RS04140	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B1H20_RS04145	COG3201	nicotinamide mononucleotide transporter
B1H20_RS04170	COG0738	Major facilitator superfamily
B1H20_RS04175	COG2233	PERMEase
B1H20_RS04185	COG1012	belongs to the aldehyde dehydrogenase family
B1H20_RS04200	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
B1H20_RS04220	COG0142	geranyltranstransferase activity
B1H20_RS04235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B1H20_RS04245	COG1012	belongs to the aldehyde dehydrogenase family
B1H20_RS04260	COG2390	Transcriptional regulator
B1H20_RS04265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B1H20_RS04275	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B1H20_RS04290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B1H20_RS04300	COG1758	RNA polymerase activity
B1H20_RS04315	COG0284	orotidine-5'-phosphate decarboxylase activity
B1H20_RS04320	COG0167	dihydroorotate dehydrogenase activity
B1H20_RS04325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B1H20_RS04330	COG0505	Belongs to the CarA family
B1H20_RS04340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B1H20_RS04345	COG0540	Belongs to the ATCase OTCase family
B1H20_RS04350	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B1H20_RS04360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B1H20_RS04365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B1H20_RS04370	COG0006	proline dipeptidase activity
B1H20_RS04380	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B1H20_RS04385	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B1H20_RS04390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B1H20_RS04395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B1H20_RS04410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B1H20_RS04415	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B1H20_RS04435	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B1H20_RS04455	COG0124	histidyl-tRNA synthetase
B1H20_RS04470	COG1196	nuclear chromosome segregation
B1H20_RS04490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B1H20_RS04495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B1H20_RS04500	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1H20_RS04505	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1H20_RS04515	COG2255	four-way junction helicase activity
B1H20_RS04520	COG0632	four-way junction helicase activity
B1H20_RS04525	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B1H20_RS04530	COG0217	transcriptional regulatory protein
B1H20_RS04535	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B1H20_RS04540	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
B1H20_RS04550	COG0438	transferase activity, transferring glycosyl groups
B1H20_RS04555	COG1560	Kdo2-lipid A biosynthetic process
B1H20_RS04560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B1H20_RS04580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B1H20_RS04595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B1H20_RS04650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B1H20_RS04705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B1H20_RS04705	COG1648	precorrin-2 dehydrogenase activity
B1H20_RS04710	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B1H20_RS04725	COG1464	Belongs to the NlpA lipoprotein family
B1H20_RS04730	COG2011	ABC-type metal ion transport system permease component
B1H20_RS04770	COG0477	Major facilitator Superfamily
B1H20_RS04780	COG3973	AAA domain
B1H20_RS04790	COG0165	Argininosuccinate lyase
B1H20_RS04795	COG0137	argininosuccinate synthase activity
B1H20_RS04810	COG1438	arginine binding
B1H20_RS04815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B1H20_RS04820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B1H20_RS04825	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B1H20_RS04830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B1H20_RS04890	COG0697	spore germination
B1H20_RS04900	COG1649	PFAM Uncharacterised BCR, COG1649
B1H20_RS04925	COG0072	phenylalanine-tRNA ligase activity
B1H20_RS04925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B1H20_RS04930	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B1H20_RS04935	COG5002	protein histidine kinase activity
B1H20_RS04940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B1H20_RS04945	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B1H20_RS04950	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B1H20_RS04955	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B1H20_RS04965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B1H20_RS05025	COG4175	Glycine betaine
B1H20_RS05025	COG0517	IMP dehydrogenase activity
B1H20_RS05030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B1H20_RS05060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B1H20_RS05065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B1H20_RS05105	COG0805	protein transport
B1H20_RS05110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1H20_RS05130	COG2378	regulation of single-species biofilm formation
B1H20_RS05140	COG0545	Peptidyl-prolyl cis-trans isomerase
B1H20_RS05145	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B1H20_RS05155	COG1609	Transcriptional regulator
B1H20_RS05160	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B1H20_RS05165	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
B1H20_RS05180	COG4122	O-methyltransferase activity
B1H20_RS05185	COG1222	aaa ATPase
B1H20_RS05210	COG1994	Peptidase M50
B1H20_RS05210	COG0517	IMP dehydrogenase activity
B1H20_RS05220	COG2197	response regulator
B1H20_RS05225	COG4166	transmembrane transport
B1H20_RS05230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B1H20_RS05235	COG1410	methionine synthase
B1H20_RS05235	COG0646	methionine synthase
B1H20_RS05240	COG1414	Transcriptional regulator
B1H20_RS05245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B1H20_RS05250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B1H20_RS05255	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B1H20_RS05260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H20_RS05270	COG0215	cysteine-tRNA ligase activity
B1H20_RS05290	COG0598	Magnesium transport protein CorA
B1H20_RS05300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H20_RS05305	COG0667	Aldo Keto reductase
B1H20_RS05335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1H20_RS05345	COG0564	pseudouridine synthase activity
B1H20_RS05360	COG2186	Transcriptional regulator
B1H20_RS05365	COG3265	gluconokinase activity
B1H20_RS05390	COG3573	Dehydrogenase
B1H20_RS05395	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B1H20_RS05400	COG2149	membrane
B1H20_RS05420	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS05425	COG4935	Belongs to the peptidase S8 family
B1H20_RS05425	COG2234	aminopeptidase activity
B1H20_RS05435	COG0318	PFAM AMP-dependent synthetase and ligase
B1H20_RS05440	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS05445	COG3876	Protein conserved in bacteria
B1H20_RS05480	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS05495	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B1H20_RS05505	COG2318	DinB family
B1H20_RS05515	COG2851	Citrate transporter
B1H20_RS05520	COG1309	transcriptional regulator
B1H20_RS05540	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
B1H20_RS05545	COG2188	Transcriptional regulator
B1H20_RS05555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1H20_RS05565	COG2755	lipolytic protein G-D-S-L family
B1H20_RS05575	COG1725	Transcriptional regulator
B1H20_RS05590	COG0346	lactoylglutathione lyase activity
B1H20_RS05610	COG4565	transcriptional regulatory protein
B1H20_RS05645	COG4585	Histidine kinase
B1H20_RS05650	COG2197	response regulator
B1H20_RS05670	COG0641	radical SAM
B1H20_RS05700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H20_RS05705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H20_RS05710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1H20_RS05715	COG1126	abc transporter atp-binding protein
B1H20_RS05730	COG0765	amino acid transport
B1H20_RS05735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1H20_RS05745	COG1799	cell septum assembly
B1H20_RS05750	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS05755	COG0477	Major facilitator Superfamily
B1H20_RS05760	COG0671	phosphoesterase, PA-phosphatase related
B1H20_RS05775	COG0438	transferase activity, transferring glycosyl groups
B1H20_RS05790	COG1160	GTP binding
B1H20_RS05800	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B1H20_RS05825	COG0494	nUDIX hydrolase
B1H20_RS05840	COG1187	pseudouridine synthase activity
B1H20_RS05845	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B1H20_RS05850	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B1H20_RS05870	COG0686	Belongs to the AlaDH PNT family
B1H20_RS05880	COG0494	nUDIX hydrolase
B1H20_RS05885	COG0504	CTP synthase activity
B1H20_RS05890	COG3387	PFAM Glycoside hydrolase 15-related
B1H20_RS05915	COG0497	DNA recombination
B1H20_RS05920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B1H20_RS05940	COG1120	ATPase activity
B1H20_RS05945	COG0647	UMP catabolic process
B1H20_RS05980	COG2094	Belongs to the DNA glycosylase MPG family
B1H20_RS05990	COG1881	PFAM PEBP family protein
B1H20_RS06015	COG1119	ATPase activity
B1H20_RS06025	COG2197	response regulator
B1H20_RS06030	COG4585	Histidine kinase
B1H20_RS06040	COG1131	(ABC) transporter
B1H20_RS06040	COG1716	ATPase activity
B1H20_RS06040	COG0842	Transport permease protein
B1H20_RS06045	COG3830	Belongs to the UPF0237 family
B1H20_RS06045	COG0560	Phosphoserine phosphatase
B1H20_RS06065	COG2186	Transcriptional regulator
B1H20_RS06075	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B1H20_RS06080	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS06105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B1H20_RS06110	COG2261	transglycosylase associated protein
B1H20_RS06125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B1H20_RS06130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1H20_RS06140	COG1404	Belongs to the peptidase S8 family
B1H20_RS06170	COG3387	PFAM Glycoside hydrolase 15-related
B1H20_RS06210	COG1024	Enoyl-CoA hydratase
B1H20_RS06220	COG0488	(ABC) transporter
B1H20_RS06245	COG0235	Class ii aldolase
B1H20_RS06260	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
B1H20_RS06265	COG1492	cobalamin metabolic process
B1H20_RS06280	COG1797	cobyrinic acid a,c-diamide synthase activity
B1H20_RS06305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B1H20_RS06335	COG1902	pentaerythritol trinitrate reductase activity
B1H20_RS06380	COG4585	Histidine kinase
B1H20_RS06385	COG2197	response regulator
B1H20_RS06390	COG0768	penicillin binding
B1H20_RS06420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1H20_RS06425	COG2171	N-acyltransferase activity
B1H20_RS06435	COG3226	Transcriptional regulator
B1H20_RS06450	COG2151	metal-sulfur cluster biosynthetic enzyme
B1H20_RS06455	COG0822	iron-sulfur transferase activity
B1H20_RS06460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B1H20_RS06465	COG0396	ATPase activity
B1H20_RS06475	COG0719	Fe-S assembly protein
B1H20_RS06510	COG0109	protoheme IX farnesyltransferase activity
B1H20_RS06520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B1H20_RS06535	COG0363	glucosamine-6-phosphate deaminase activity
B1H20_RS06545	COG4195	phage-related replication protein
B1H20_RS06560	COG0166	Belongs to the GPI family
B1H20_RS06570	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B1H20_RS06575	COG0149	triose-phosphate isomerase activity
B1H20_RS06580	COG0126	phosphoglycerate kinase activity
B1H20_RS06585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B1H20_RS06590	COG1481	regulation of sporulation
B1H20_RS06595	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B1H20_RS06600	COG1660	Displays ATPase and GTPase activities
B1H20_RS06605	COG0322	excinuclease ABC activity
B1H20_RS06630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B1H20_RS06660	COG0556	nucleotide-excision repair
B1H20_RS06670	COG0584	glycerophosphoryl diester phosphodiesterase
B1H20_RS06680	COG2814	Major facilitator Superfamily
B1H20_RS06690	COG2313	pseudouridylate synthase activity
B1H20_RS06710	COG0436	Aminotransferase
B1H20_RS06730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B1H20_RS06740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B1H20_RS06755	COG0237	dephospho-CoA kinase activity
B1H20_RS06780	COG1643	Atp-dependent helicase
B1H20_RS06810	COG2050	protein possibly involved in aromatic compounds catabolism
B1H20_RS06820	COG0559	Belongs to the binding-protein-dependent transport system permease family
B1H20_RS06860	COG0737	Belongs to the 5'-nucleotidase family
B1H20_RS06895	COG1605	Chorismate mutase
B1H20_RS06895	COG0287	Prephenate dehydrogenase
B1H20_RS06930	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS06935	COG1024	Enoyl-CoA hydratase
B1H20_RS06960	COG1278	Cold shock
B1H20_RS06965	COG0183	Belongs to the thiolase family
B1H20_RS06970	COG1309	transcriptional regulator
B1H20_RS06980	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS06985	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS07005	COG0705	Rhomboid family
B1H20_RS07015	COG0067	glutamate synthase
B1H20_RS07015	COG0070	glutamate synthase
B1H20_RS07015	COG0069	glutamate synthase activity
B1H20_RS07045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1H20_RS07050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1H20_RS07060	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B1H20_RS07070	COG0159	tryptophan synthase activity
B1H20_RS07075	COG0133	tryptophan synthase activity
B1H20_RS07085	COG0134	indole-3-glycerol-phosphate synthase activity
B1H20_RS07105	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B1H20_RS07110	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B1H20_RS07130	COG0107	imidazoleglycerol-phosphate synthase activity
B1H20_RS07135	COG0251	oxidation-reduction process
B1H20_RS07140	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B1H20_RS07145	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B1H20_RS07150	COG0131	Imidazoleglycerol-phosphate dehydratase
B1H20_RS07155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B1H20_RS07160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B1H20_RS07180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B1H20_RS07200	COG1432	Conserved Protein
B1H20_RS07210	COG0587	DNA-directed DNA polymerase activity
B1H20_RS07255	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B1H20_RS07270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B1H20_RS07275	COG3599	regulation of cell shape
B1H20_RS07285	COG1799	cell septum assembly
B1H20_RS07290	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B1H20_RS07315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B1H20_RS07325	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B1H20_RS07330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B1H20_RS07340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B1H20_RS07345	COG0768	penicillin binding
B1H20_RS07355	COG0275	rRNA processing
B1H20_RS07365	COG0714	Associated with various cellular activities
B1H20_RS07385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B1H20_RS07395	COG0577	efflux transmembrane transporter activity
B1H20_RS07395	COG1136	(ABC) transporter
B1H20_RS07415	COG1233	COG1233 Phytoene dehydrogenase and related
B1H20_RS07430	COG0352	thiamine-phosphate diphosphorylase activity
B1H20_RS07450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1H20_RS07450	COG2022	thiamine diphosphate biosynthetic process
B1H20_RS07460	COG2022	thiamine diphosphate biosynthetic process
B1H20_RS07465	COG2815	serine threonine protein kinase
B1H20_RS07465	COG0515	serine threonine protein kinase
B1H20_RS07470	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B1H20_RS07475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B1H20_RS07480	COG2193	ferroxidase activity
B1H20_RS07490	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
B1H20_RS07500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1H20_RS07505	COG2197	response regulator
B1H20_RS07535	COG1940	carbohydrate kinase activity
B1H20_RS07545	COG0003	Pfam Anion-transporting ATPase
B1H20_RS07565	COG0438	transferase activity, transferring glycosyl groups
B1H20_RS07610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B1H20_RS07615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B1H20_RS07620	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B1H20_RS07625	COG0723	plastoquinol--plastocyanin reductase activity
B1H20_RS07630	COG2010	Cytochrome c
B1H20_RS07635	COG1845	cytochrome c oxidase, subunit III
B1H20_RS07645	COG1376	ErfK ybiS ycfS ynhG family protein
B1H20_RS07655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B1H20_RS07660	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B1H20_RS07670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1H20_RS07690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B1H20_RS07700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1H20_RS07705	COG2197	response regulator
B1H20_RS07710	COG4585	Histidine kinase
B1H20_RS07735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1H20_RS07750	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B1H20_RS07765	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B1H20_RS07770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B1H20_RS07775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B1H20_RS07780	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1H20_RS07790	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B1H20_RS07810	COG1090	epimerase
B1H20_RS07825	COG0321	lipoyl(octanoyl) transferase activity
B1H20_RS07830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B1H20_RS07855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1H20_RS07860	COG3896	Chloramphenicol phosphotransferase-like protein
B1H20_RS07865	COG2362	D-Aminopeptidase
B1H20_RS07885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1H20_RS07890	COG0673	inositol 2-dehydrogenase activity
B1H20_RS07915	COG0745	RESPONSE REGULATOR receiver
B1H20_RS07920	COG2409	Drug exporters of the RND superfamily
B1H20_RS07925	COG4585	Histidine kinase
B1H20_RS07930	COG2197	response regulator
B1H20_RS07990	COG0366	Alpha amylase catalytic
B1H20_RS07995	COG0395	ABC-type sugar transport system, permease component
B1H20_RS08005	COG2182	Extracellular solute-binding protein
B1H20_RS08010	COG1609	Transcriptional regulator
B1H20_RS08035	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B1H20_RS08045	COG2890	protein-(glutamine-N5) methyltransferase activity
B1H20_RS08050	COG0477	Major facilitator Superfamily
B1H20_RS08085	COG0494	nUDIX hydrolase
B1H20_RS08115	COG0174	glutamine synthetase
B1H20_RS08130	COG2132	Multicopper oxidase
B1H20_RS08135	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B1H20_RS08135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B1H20_RS08140	COG2814	Major facilitator Superfamily
B1H20_RS08155	COG0477	Major facilitator Superfamily
B1H20_RS08160	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B1H20_RS08180	COG1994	Peptidase M50
B1H20_RS08240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS08245	COG1120	ATPase activity
B1H20_RS08265	COG1834	amidinotransferase
B1H20_RS08280	COG2814	Major facilitator Superfamily
B1H20_RS08290	COG3540	Alkaline phosphatase
B1H20_RS08295	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS08305	COG0384	phenazine biosynthesis protein PhzF
B1H20_RS08345	COG2273	Hydrolase Family 16
B1H20_RS08370	COG3022	response to hydroperoxide
B1H20_RS08375	COG0800	Aldolase
B1H20_RS08390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B1H20_RS08395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B1H20_RS08410	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS08420	COG2030	dehydratase
B1H20_RS08430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B1H20_RS08435	COG0183	Belongs to the thiolase family
B1H20_RS08440	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS08450	COG3340	Belongs to the peptidase S51 family
B1H20_RS08465	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B1H20_RS08470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1H20_RS08490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H20_RS08515	COG0438	transferase activity, transferring glycosyl groups
B1H20_RS08520	COG1309	transcriptional regulator
B1H20_RS08555	COG3845	ABC transporter
B1H20_RS08565	COG0183	Belongs to the thiolase family
B1H20_RS08570	COG2124	cytochrome p450
B1H20_RS08615	COG2259	Doxx family
B1H20_RS08695	COG1358	cellular component organization or biogenesis
B1H20_RS08740	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
B1H20_RS08750	COG0477	Major facilitator Superfamily
B1H20_RS08755	COG1309	transcriptional regulator
B1H20_RS08770	COG4585	Histidine kinase
B1H20_RS08775	COG2197	response regulator
B1H20_RS08790	COG0667	Aldo Keto reductase
B1H20_RS08795	COG0789	Transcriptional regulator
B1H20_RS08805	COG2205	protein histidine kinase activity
B1H20_RS08810	COG0745	RESPONSE REGULATOR receiver
B1H20_RS08820	COG0667	Aldo Keto reductase
B1H20_RS08830	COG1929	Belongs to the glycerate kinase type-1 family
B1H20_RS08910	COG1404	Belongs to the peptidase S8 family
B1H20_RS08970	COG2957	Belongs to the agmatine deiminase family
B1H20_RS08985	COG1741	Belongs to the pirin family
B1H20_RS09030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1H20_RS09035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H20_RS09040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H20_RS09070	COG1764	response to oxidative stress
B1H20_RS09075	COG2130	NADP-dependent
B1H20_RS09105	COG1522	sequence-specific DNA binding
B1H20_RS09115	COG0318	PFAM AMP-dependent synthetase and ligase
B1H20_RS09120	COG0825	malonyl-CoA metabolic process
B1H20_RS09120	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B1H20_RS09125	COG0477	Major facilitator Superfamily
B1H20_RS09135	COG2801	Transposase and inactivated derivatives
B1H20_RS09140	COG2801	Transposase and inactivated derivatives
B1H20_RS09190	COG1070	Carbohydrate kinase
B1H20_RS09205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B1H20_RS09210	COG0358	DNA primase activity
B1H20_RS09220	COG0232	Belongs to the dGTPase family. Type 2 subfamily
B1H20_RS09230	COG2949	membrane
B1H20_RS09275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1H20_RS09275	COG2146	nitrite reductase [NAD(P)H] activity
B1H20_RS09300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B1H20_RS09300	COG0574	Belongs to the PEP-utilizing enzyme family
B1H20_RS09305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B1H20_RS09310	COG3842	ATPase activity
B1H20_RS09330	COG2188	Transcriptional regulator
B1H20_RS09355	COG0477	Major facilitator Superfamily
B1H20_RS09360	COG2066	Belongs to the glutaminase family
B1H20_RS09535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1H20_RS09550	COG0277	FAD linked oxidase domain protein
B1H20_RS09555	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS09560	COG2124	cytochrome p450
B1H20_RS09595	COG0477	Major facilitator Superfamily
B1H20_RS09600	COG2345	Transcriptional regulator
B1H20_RS09625	COG0367	asparagine synthase
B1H20_RS09635	COG0662	Cupin 2, conserved barrel domain protein
B1H20_RS09640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H20_RS09645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H20_RS09655	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS09670	COG3104	oligopeptide transport
B1H20_RS09680	COG0423	glycine-tRNA ligase activity
B1H20_RS09690	COG1121	(ABC) transporter
B1H20_RS09695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B1H20_RS09705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B1H20_RS09710	COG1381	Involved in DNA repair and RecF pathway recombination
B1H20_RS09720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B1H20_RS09735	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B1H20_RS09750	COG2315	Protein conserved in bacteria
B1H20_RS09760	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B1H20_RS09770	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B1H20_RS09770	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B1H20_RS09780	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B1H20_RS09785	COG1234	tRNA 3'-trailer cleavage
B1H20_RS09790	COG0537	adenosine 5'-monophosphoramidase activity
B1H20_RS09805	COG0484	heat shock protein binding
B1H20_RS09810	COG1420	regulation of RNA biosynthetic process
B1H20_RS09850	COG0481	GTPase activity
B1H20_RS09855	COG0268	Binds directly to 16S ribosomal RNA
B1H20_RS09885	COG1555	photosystem II stabilization
B1H20_RS09890	COG1307	EDD domain protein, DegV family
B1H20_RS09900	COG0495	leucyl-tRNA aminoacylation
B1H20_RS09925	COG0588	phosphoglycerate mutase activity
B1H20_RS09930	COG0799	negative regulation of ribosome biogenesis
B1H20_RS09940	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B1H20_RS09945	COG0501	Belongs to the peptidase M48B family
B1H20_RS09960	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B1H20_RS09970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B1H20_RS09995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B1H20_RS10000	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B1H20_RS10005	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B1H20_RS10010	COG1530	ribonuclease E activity
B1H20_RS10035	COG0772	Belongs to the SEDS family
B1H20_RS10040	COG0768	penicillin binding
B1H20_RS10055	COG1077	Cell shape determining protein MreB Mrl
B1H20_RS10060	COG0105	UTP biosynthetic process
B1H20_RS10070	COG0285	dihydrofolate synthase activity
B1H20_RS10075	COG0525	valine-tRNA ligase activity
B1H20_RS10085	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B1H20_RS10090	COG0740	serine-type endopeptidase activity
B1H20_RS10095	COG0740	serine-type endopeptidase activity
B1H20_RS10100	COG0544	peptidyl-prolyl cis-trans isomerase activity
B1H20_RS10120	COG3594	Acyltransferase
B1H20_RS10130	COG0475	glutathione-regulated potassium exporter activity
B1H20_RS10150	COG1113	amino acid transport
B1H20_RS10160	COG1268	BioY protein
B1H20_RS10165	COG1113	amino acid transport
B1H20_RS10170	COG1113	amino acid transport
B1H20_RS10175	COG0584	glycerophosphoryl diester phosphodiesterase
B1H20_RS10180	COG0783	Belongs to the Dps family
B1H20_RS10190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B1H20_RS10195	COG0640	Transcriptional regulator
B1H20_RS10210	COG0110	maltose O-acetyltransferase activity
B1H20_RS10215	COG1404	Belongs to the peptidase S8 family
B1H20_RS10240	COG2252	PERMEase
B1H20_RS10250	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B1H20_RS10295	COG4266	Belongs to the allantoicase family
B1H20_RS10300	COG0583	DNA-binding transcription factor activity
B1H20_RS10320	COG3291	Pkd domain containing protein
B1H20_RS10320	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B1H20_RS10330	COG0668	transmembrane transport
B1H20_RS10360	COG1175	transmembrane transport
B1H20_RS10365	COG0395	ABC-type sugar transport system, permease component
B1H20_RS10370	COG1486	melibiose metabolic process
B1H20_RS10385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1H20_RS10415	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B1H20_RS10420	COG2346	COG2346, Truncated hemoglobins
B1H20_RS10435	COG1136	(ABC) transporter
B1H20_RS10435	COG0577	efflux transmembrane transporter activity
B1H20_RS10460	COG0629	single-stranded DNA binding
B1H20_RS10500	COG1674	ftsk spoiiie
B1H20_RS10595	COG2197	response regulator
B1H20_RS10600	COG4585	Histidine kinase
B1H20_RS10620	COG3962	Belongs to the TPP enzyme family
B1H20_RS10625	COG3718	enzyme involved in inositol metabolism
B1H20_RS10635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1H20_RS10645	COG2318	DinB family
B1H20_RS10660	COG2409	Drug exporters of the RND superfamily
B1H20_RS10685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B1H20_RS10710	COG0596	Alpha beta hydrolase
B1H20_RS10755	COG0673	inositol 2-dehydrogenase activity
B1H20_RS10760	COG1609	Transcriptional regulator
B1H20_RS10795	COG0515	serine threonine protein kinase
B1H20_RS10825	COG1404	Belongs to the peptidase S8 family
B1H20_RS10850	COG1472	Belongs to the glycosyl hydrolase 3 family
B1H20_RS10865	COG0477	Major facilitator Superfamily
B1H20_RS10895	COG0028	Belongs to the TPP enzyme family
B1H20_RS10935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B1H20_RS10960	COG1946	Acyl-CoA thioesterase
B1H20_RS10990	COG1309	transcriptional regulator
B1H20_RS10995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1H20_RS11010	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS11030	COG0076	glutamate decarboxylase activity
B1H20_RS11035	COG3486	L-lysine 6-monooxygenase (NADPH) activity
B1H20_RS11060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B1H20_RS11070	COG4977	sequence-specific DNA binding
B1H20_RS11105	COG0395	ABC-type sugar transport system, permease component
B1H20_RS11120	COG2985	domain, Protein
B1H20_RS11135	COG0745	RESPONSE REGULATOR receiver
B1H20_RS11210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H20_RS11220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1H20_RS11230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1H20_RS11235	COG0765	amino acid transport
B1H20_RS11240	COG0765	amino acid transport
B1H20_RS11245	COG1126	abc transporter atp-binding protein
B1H20_RS11250	COG1414	Transcriptional regulator
B1H20_RS11260	COG3397	chitin binding
B1H20_RS11325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1H20_RS11330	COG2188	Transcriptional regulator
B1H20_RS11340	COG1940	carbohydrate kinase activity
B1H20_RS11345	COG0673	inositol 2-dehydrogenase activity
B1H20_RS11350	COG4702	Belongs to the UPF0303 family
B1H20_RS11355	COG0179	Fumarylacetoacetate (FAA) hydrolase
B1H20_RS11360	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion
B1H20_RS11360	COG0706	membrane insertase activity
B1H20_RS11370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1H20_RS11380	COG3764	Sortase (surface protein transpeptidase)
B1H20_RS11425	COG3655	Transcriptional regulator
B1H20_RS11460	COG3135	benzoate transporter
B1H20_RS11465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1H20_RS11480	COG2175	clavaminate synthase activity
B1H20_RS11490	COG0596	Alpha beta hydrolase
B1H20_RS11500	COG2733	membrane
B1H20_RS11520	COG4555	ABC transporter
B1H20_RS11535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1H20_RS11560	COG0477	Major facilitator Superfamily
B1H20_RS11580	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B1H20_RS11590	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B1H20_RS11595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B1H20_RS11600	COG1263	PTS System
B1H20_RS11605	COG1263	PTS System
B1H20_RS11615	COG1234	tRNA 3'-trailer cleavage
B1H20_RS11640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS11655	COG1113	amino acid transport
B1H20_RS11665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B1H20_RS11675	COG1335	isochorismatase
B1H20_RS11710	COG0277	FAD linked oxidase domain protein
B1H20_RS11720	COG3185	4-Hydroxyphenylpyruvate dioxygenase
B1H20_RS11730	COG1174	glycine betaine transport
B1H20_RS11735	COG1125	glycine betaine transport
B1H20_RS11735	COG0517	IMP dehydrogenase activity
B1H20_RS11740	COG1174	glycine betaine transport
B1H20_RS11745	COG1732	Glycine betaine
B1H20_RS11765	COG3480	Lon protease (S16) C-terminal proteolytic domain
B1H20_RS11795	COG3654	unkown
B1H20_RS11855	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B1H20_RS11860	COG0395	ABC-type sugar transport system, permease component
B1H20_RS11870	COG2182	Extracellular solute-binding protein
B1H20_RS11880	COG1678	Uncharacterized ACR, COG1678
B1H20_RS11885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B1H20_RS11890	COG0776	regulation of translation
B1H20_RS11900	COG3973	AAA domain
B1H20_RS11900	COG3973	AAA domain
B1H20_RS11925	COG2223	nitrite transmembrane transporter activity
B1H20_RS11930	COG0583	DNA-binding transcription factor activity
B1H20_RS11980	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B1H20_RS11985	COG0793	Belongs to the peptidase S41A family
B1H20_RS11990	COG2177	Part of the ABC transporter FtsEX involved in
B1H20_RS11995	COG2884	Cell division ATP-binding protein ftsE
B1H20_RS12010	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B1H20_RS12015	COG0515	serine threonine protein kinase
B1H20_RS12020	COG0515	serine threonine protein kinase
B1H20_RS12030	COG1653	transport
B1H20_RS12035	COG1175	transmembrane transport
B1H20_RS12040	COG0395	ABC-type sugar transport system, permease component
B1H20_RS12045	COG1442	glycosyl transferase family 8
B1H20_RS12045	COG1216	Glycosyl transferase, family 2
B1H20_RS12050	COG0438	transferase activity, transferring glycosyl groups
B1H20_RS12055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1H20_RS12060	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1H20_RS12065	COG4122	O-methyltransferase activity
B1H20_RS12070	COG2226	methyltransferase
B1H20_RS12070	COG1073	alpha beta
B1H20_RS12075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1H20_RS12080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1H20_RS12090	COG1309	transcriptional regulator
B1H20_RS12100	COG1134	teichoic acid transport
B1H20_RS12105	COG2902	Dehydrogenase
B1H20_RS12125	COG0653	protein targeting
B1H20_RS12140	COG2197	response regulator
B1H20_RS12145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B1H20_RS12155	COG0823	Involved in the tonB-independent uptake of proteins
B1H20_RS12160	COG5002	protein histidine kinase activity
B1H20_RS12160	COG5000	phosphorelay sensor kinase activity
B1H20_RS12165	COG0745	RESPONSE REGULATOR receiver
B1H20_RS12170	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B1H20_RS12190	COG0714	Associated with various cellular activities
B1H20_RS12235	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B1H20_RS12255	COG2835	tetraacyldisaccharide 4'-kinase activity
B1H20_RS12260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1H20_RS12295	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B1H20_RS12300	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
B1H20_RS12300	COG0778	Nitroreductase
B1H20_RS12305	COG0531	amino acid
B1H20_RS12330	COG1316	TRANSCRIPTIONal
B1H20_RS12335	COG1316	TRANSCRIPTIONal
B1H20_RS12345	COG1316	TRANSCRIPTIONal
B1H20_RS12355	COG1316	TRANSCRIPTIONal
B1H20_RS12435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B1H20_RS12465	COG2205	protein histidine kinase activity
B1H20_RS12470	COG0745	RESPONSE REGULATOR receiver
B1H20_RS12475	COG3104	oligopeptide transport
B1H20_RS12505	COG1366	Belongs to the anti-sigma-factor antagonist family
B1H20_RS12510	COG1191	sigma factor activity
B1H20_RS12515	COG1228	amidohydrolase
B1H20_RS12525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1H20_RS12530	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B1H20_RS12535	COG0531	amino acid
B1H20_RS12575	COG2755	lipolytic protein G-D-S-L family
B1H20_RS12580	COG0183	Belongs to the thiolase family
B1H20_RS12605	COG1136	(ABC) transporter
B1H20_RS12605	COG0577	efflux transmembrane transporter activity
B1H20_RS12610	COG0577	efflux transmembrane transporter activity
B1H20_RS12610	COG1136	(ABC) transporter
B1H20_RS12615	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B1H20_RS12620	COG1252	NADH dehydrogenase
B1H20_RS12640	COG0148	phosphopyruvate hydratase activity
B1H20_RS12650	COG1652	LysM domain
B1H20_RS12675	COG2815	serine threonine protein kinase
B1H20_RS12675	COG0515	serine threonine protein kinase
B1H20_RS12695	COG1335	isochorismatase
B1H20_RS12700	COG0456	acetyltransferase
B1H20_RS12750	COG1473	amidohydrolase
B1H20_RS12805	COG3629	intracellular signal transduction
B1H20_RS12805	COG3903	Transcriptional regulator
B1H20_RS12815	COG0577	efflux transmembrane transporter activity
B1H20_RS12820	COG1136	(ABC) transporter
B1H20_RS12830	COG0477	Major facilitator Superfamily
B1H20_RS12835	COG0346	lactoylglutathione lyase activity
B1H20_RS12880	COG2124	cytochrome p450
B1H20_RS12910	COG4585	Histidine kinase
B1H20_RS12925	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B1H20_RS12930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B1H20_RS12935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B1H20_RS12940	COG0193	aminoacyl-tRNA hydrolase activity
B1H20_RS12945	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B1H20_RS12970	COG4106	trans-aconitate 2-methyltransferase activity
B1H20_RS12975	COG1846	Transcriptional regulator
B1H20_RS12980	COG2197	response regulator
B1H20_RS12990	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
B1H20_RS13005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1H20_RS13030	COG0488	(ABC) transporter
B1H20_RS13050	COG4115	mRNA cleavage
B1H20_RS13065	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B1H20_RS13070	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B1H20_RS13075	COG0084	hydrolase, TatD family'
B1H20_RS13100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B1H20_RS13150	COG2223	nitrite transmembrane transporter activity
B1H20_RS13155	COG2207	Transcriptional regulator
B1H20_RS13160	COG0442	prolyl-tRNA aminoacylation
B1H20_RS13180	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
B1H20_RS13185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1H20_RS13205	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS13210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B1H20_RS13220	COG2409	Drug exporters of the RND superfamily
B1H20_RS13230	COG4946	Tricorn protease homolog
B1H20_RS13230	COG0793	Belongs to the peptidase S41A family
B1H20_RS13240	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS13250	COG2072	flavoprotein involved in K transport
B1H20_RS13260	COG0708	Exodeoxyribonuclease III
B1H20_RS13290	COG2340	Cysteine-rich secretory protein family
B1H20_RS13330	COG0521	Mo-molybdopterin cofactor biosynthetic process
B1H20_RS13335	COG0315	cyclic pyranopterin monophosphate synthase activity
B1H20_RS13345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B1H20_RS13350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B1H20_RS13360	COG3263	regulation of cellular component size
B1H20_RS13375	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B1H20_RS13400	COG0437	4 iron, 4 sulfur cluster binding
B1H20_RS13405	COG0243	molybdopterin cofactor binding
B1H20_RS13425	COG0477	Major facilitator Superfamily
B1H20_RS13445	COG3384	dioxygenase
B1H20_RS13450	COG1846	Transcriptional regulator
B1H20_RS13470	COG0318	PFAM AMP-dependent synthetase and ligase
B1H20_RS13500	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS13505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H20_RS13535	COG1686	Belongs to the peptidase S11 family
B1H20_RS13615	COG4106	trans-aconitate 2-methyltransferase activity
B1H20_RS13635	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B1H20_RS13650	COG3386	PFAM SMP-30 Gluconolaconase
B1H20_RS13655	COG0768	penicillin binding
B1H20_RS13715	COG0667	Aldo Keto reductase
B1H20_RS13775	COG1196	nuclear chromosome segregation
B1H20_RS13775	COG0741	lytic transglycosylase activity
B1H20_RS13775	COG0739	heme binding
B1H20_RS13795	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
B1H20_RS13805	COG0183	Belongs to the thiolase family
B1H20_RS13810	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS13825	COG2770	Histidine kinase
B1H20_RS13825	COG2208	phosphoserine phosphatase activity
B1H20_RS13845	COG1309	transcriptional regulator
B1H20_RS13855	COG1301	dicarboxylic acid transport
B1H20_RS13865	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B1H20_RS13875	COG0163	prenyltransferase activity
B1H20_RS13890	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B1H20_RS13900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B1H20_RS13905	COG1333	cytochrome c biogenesis protein
B1H20_RS13910	COG0785	Cytochrome C biogenesis protein
B1H20_RS13915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1H20_RS13925	COG0406	alpha-ribazole phosphatase activity
B1H20_RS13930	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B1H20_RS13970	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B1H20_RS13980	COG1690	Belongs to the RtcB family
B1H20_RS14005	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
B1H20_RS14010	COG0018	arginyl-trna synthetase
B1H20_RS14065	COG0583	DNA-binding transcription factor activity
B1H20_RS14070	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS14075	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS14080	COG0515	serine threonine protein kinase
B1H20_RS14125	COG2267	carboxylic ester hydrolase activity
B1H20_RS14135	COG2084	Dehydrogenase
B1H20_RS14140	COG1309	transcriptional regulator
B1H20_RS14175	COG0671	phosphoesterase, PA-phosphatase related
B1H20_RS14190	COG0667	Aldo Keto reductase
B1H20_RS14195	COG0154	amidase activity
B1H20_RS14220	COG2252	PERMEase
B1H20_RS14230	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B1H20_RS14250	COG2814	Major facilitator Superfamily
B1H20_RS14260	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B1H20_RS14265	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
B1H20_RS14275	COG1278	Cold shock
B1H20_RS14300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS14305	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS14310	COG1120	ATPase activity
B1H20_RS14315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B1H20_RS14360	COG1061	Type III restriction enzyme res subunit
B1H20_RS14370	COG1120	ATPase activity
B1H20_RS14395	COG3973	AAA domain
B1H20_RS14415	COG1984	allophanate hydrolase subunit 2
B1H20_RS14425	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B1H20_RS14435	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1H20_RS14440	COG0640	Transcriptional regulator
B1H20_RS14445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B1H20_RS14450	COG3226	Transcriptional regulator
B1H20_RS14475	COG1737	Transcriptional regulator
B1H20_RS14480	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B1H20_RS14485	COG1263	PTS System
B1H20_RS14485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B1H20_RS14505	COG4257	antibiotic catabolic process
B1H20_RS14535	COG2154	pterin-4-alpha-carbinolamine dehydratase
B1H20_RS14565	COG2204	response regulator
B1H20_RS14570	COG4251	negative regulation of phosphorylation
B1H20_RS14610	COG1175	transmembrane transport
B1H20_RS14615	COG0395	ABC-type sugar transport system, permease component
B1H20_RS14650	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B1H20_RS14685	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B1H20_RS14730	COG1595	DNA-templated transcription, initiation
B1H20_RS14740	COG1132	(ABC) transporter
B1H20_RS14785	COG0463	Glycosyl transferase, family 2
B1H20_RS14790	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
B1H20_RS14800	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
B1H20_RS14825	COG2197	response regulator
B1H20_RS14865	COG1136	(ABC) transporter
B1H20_RS14865	COG0577	efflux transmembrane transporter activity
B1H20_RS14875	COG2197	response regulator
B1H20_RS14930	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B1H20_RS14935	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B1H20_RS14940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B1H20_RS14940	COG1754	DNA topoisomerase type I activity
B1H20_RS14950	COG2890	protein-(glutamine-N5) methyltransferase activity
B1H20_RS14960	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
B1H20_RS14970	COG1366	Belongs to the anti-sigma-factor antagonist family
B1H20_RS14975	COG1205	dead DEAH box helicase
B1H20_RS14975	COG1111	helicase
B1H20_RS15035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1H20_RS15040	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B1H20_RS15050	COG2267	carboxylic ester hydrolase activity
B1H20_RS15080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1H20_RS15090	COG0251	oxidation-reduction process
B1H20_RS15100	COG0003	Pfam Anion-transporting ATPase
B1H20_RS15115	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B1H20_RS15120	COG1610	YqeY-like protein
B1H20_RS15125	COG1408	metallophosphoesterase
B1H20_RS15150	COG1609	Transcriptional regulator
B1H20_RS15190	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B1H20_RS15295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B1H20_RS15310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B1H20_RS15315	COG2755	lipolytic protein G-D-S-L family
B1H20_RS15325	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B1H20_RS15345	COG1595	DNA-templated transcription, initiation
B1H20_RS15370	COG0702	epimerase
B1H20_RS15380	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B1H20_RS15385	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B1H20_RS15400	COG1802	Transcriptional regulator
B1H20_RS15405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1H20_RS15410	COG0693	protein deglycase activity
B1H20_RS15420	COG2124	cytochrome p450
B1H20_RS15430	COG0738	Major facilitator superfamily
B1H20_RS15435	COG3226	Transcriptional regulator
B1H20_RS15440	COG0667	Aldo Keto reductase
B1H20_RS15465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H20_RS15475	COG0662	Cupin 2, conserved barrel domain protein
B1H20_RS15480	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS15535	COG0590	tRNA wobble adenosine to inosine editing
B1H20_RS15545	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B1H20_RS15575	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B1H20_RS15595	COG2124	cytochrome p450
B1H20_RS15600	COG2197	response regulator
B1H20_RS15605	COG4585	Histidine kinase
B1H20_RS15610	COG0702	epimerase
B1H20_RS15620	COG3844	kynureninase activity
B1H20_RS15635	COG0477	Major facilitator Superfamily
B1H20_RS15640	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B1H20_RS15645	COG0191	fructose-bisphosphate aldolase activity
B1H20_RS15650	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B1H20_RS15665	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B1H20_RS15700	COG0542	response to heat
B1H20_RS15745	COG0789	Transcriptional regulator
B1H20_RS15750	COG0484	heat shock protein binding
B1H20_RS15755	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B1H20_RS15760	COG0443	Heat shock 70 kDa protein
B1H20_RS15765	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B1H20_RS15770	COG2181	nitrate reductase activity
B1H20_RS15770	COG0247	lactate metabolic process
B1H20_RS15790	COG0717	Belongs to the dCTP deaminase family
B1H20_RS15850	COG2188	Transcriptional regulator
B1H20_RS15890	COG1309	transcriptional regulator
B1H20_RS15895	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS15900	COG1278	Cold shock
B1H20_RS15970	COG2205	protein histidine kinase activity
B1H20_RS15975	COG0745	RESPONSE REGULATOR receiver
B1H20_RS16050	COG2409	Drug exporters of the RND superfamily
B1H20_RS16060	COG0513	Belongs to the DEAD box helicase family
B1H20_RS16065	COG1278	Cold shock
B1H20_RS16115	COG0450	alkyl hydroperoxide reductase
B1H20_RS16125	COG2268	Band 7 protein
B1H20_RS16175	COG0490	domain, Protein
B1H20_RS16180	COG0475	glutathione-regulated potassium exporter activity
B1H20_RS16185	COG0181	hydroxymethylbilane synthase activity
B1H20_RS16215	COG2255	four-way junction helicase activity
B1H20_RS16225	COG0180	Tryptophanyl-tRNA synthetase
B1H20_RS16230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H20_RS16245	COG1672	PFAM Archaeal ATPase
B1H20_RS16245	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
B1H20_RS16265	COG0431	NADPH-dependent FMN reductase
B1H20_RS16290	COG2304	oxidoreductase activity
B1H20_RS16295	COG2205	protein histidine kinase activity
B1H20_RS16300	COG0745	RESPONSE REGULATOR receiver
B1H20_RS16305	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B1H20_RS16320	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B1H20_RS16335	COG1741	Belongs to the pirin family
B1H20_RS16345	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS16355	COG1362	aminopeptidase activity
B1H20_RS16365	COG3903	Transcriptional regulator
B1H20_RS16365	COG3629	intracellular signal transduction
B1H20_RS16390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B1H20_RS16400	COG2271	Major facilitator Superfamily
B1H20_RS16415	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1H20_RS16420	COG0022	dehydrogenase e1 component
B1H20_RS16445	COG0515	serine threonine protein kinase
B1H20_RS16450	COG0515	serine threonine protein kinase
B1H20_RS16465	COG1136	(ABC) transporter
B1H20_RS16465	COG4591	ABC-type transport system involved in lipoprotein release permease component
B1H20_RS16490	COG0303	'Molybdopterin
B1H20_RS16515	COG1522	sequence-specific DNA binding
B1H20_RS16520	COG1309	transcriptional regulator
B1H20_RS16545	COG3396	Phenylacetate-CoA oxygenase
B1H20_RS16550	COG3460	Phenylacetate-CoA oxygenase
B1H20_RS16555	COG3396	Phenylacetate-CoA oxygenase
B1H20_RS16560	COG2151	metal-sulfur cluster biosynthetic enzyme
B1H20_RS16565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B1H20_RS16600	COG1716	ATPase activity
B1H20_RS16605	COG1716	ATPase activity
B1H20_RS16620	COG0768	penicillin binding
B1H20_RS16625	COG0515	serine threonine protein kinase
B1H20_RS16630	COG3764	Sortase (surface protein transpeptidase)
B1H20_RS16635	COG3764	Sortase (surface protein transpeptidase)
B1H20_RS16650	COG3764	Sortase (surface protein transpeptidase)
B1H20_RS16690	COG0515	serine threonine protein kinase
B1H20_RS16715	COG0582	viral genome integration into host DNA
B1H20_RS16770	COG0210	DNA helicase
B1H20_RS17125	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B1H20_RS17135	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
B1H20_RS17140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B1H20_RS17145	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B1H20_RS17150	COG0592	DNA-directed DNA polymerase activity
B1H20_RS17170	COG0594	ribonuclease P activity
B1H20_RS17175	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B1H20_RS17180	COG0706	membrane insertase activity
B1H20_RS17190	COG0357	Ribosomal RNA small subunit methyltransferase G
B1H20_RS17195	COG1192	Involved in chromosome partitioning
B1H20_RS17210	COG3118	belongs to the thioredoxin family
B1H20_RS17215	COG0492	ferredoxin-NADP+ reductase activity
B1H20_RS17225	COG1595	DNA-templated transcription, initiation
B1H20_RS17230	COG2815	serine threonine protein kinase
B1H20_RS17230	COG0515	serine threonine protein kinase
B1H20_RS17245	COG0617	tRNA 3'-terminal CCA addition
B1H20_RS17265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1H20_RS17290	COG0360	Binds together with S18 to 16S ribosomal RNA
B1H20_RS17295	COG0629	single-stranded DNA binding
B1H20_RS17300	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B1H20_RS17305	COG0359	binds to the 23S rRNA
B1H20_RS17315	COG0305	Participates in initiation and elongation during chromosome replication
B1H20_RS17345	COG2814	Major facilitator Superfamily
B1H20_RS17360	COG0626	cystathionine gamma-synthase activity
B1H20_RS17365	COG1950	PFAM Membrane protein of
B1H20_RS17370	COG0662	Cupin 2, conserved barrel domain protein
B1H20_RS17395	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B1H20_RS17405	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B1H20_RS17410	COG1609	Transcriptional regulator
B1H20_RS17415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B1H20_RS17420	COG1271	oxidase subunit
B1H20_RS17425	COG1294	oxidase, subunit
B1H20_RS17430	COG4988	ABC transporter
B1H20_RS17440	COG0561	phosphatase activity
B1H20_RS17450	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
B1H20_RS17455	COG0789	Transcriptional regulator
B1H20_RS17470	COG1131	(ABC) transporter
B1H20_RS17495	COG0561	phosphatase activity
B1H20_RS17500	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B1H20_RS17510	COG2837	iron assimilation
B1H20_RS17515	COG2372	response to copper ion
B1H20_RS17525	COG1999	signal sequence binding
B1H20_RS17545	COG0006	proline dipeptidase activity
B1H20_RS17560	COG0653	protein targeting
B1H20_RS17580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1H20_RS17605	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS17630	COG1595	DNA-templated transcription, initiation
B1H20_RS17635	COG0318	PFAM AMP-dependent synthetase and ligase
B1H20_RS17685	COG1252	NADH dehydrogenase
B1H20_RS17690	COG1595	DNA-templated transcription, initiation
B1H20_RS17710	COG0745	RESPONSE REGULATOR receiver
B1H20_RS17715	COG2205	protein histidine kinase activity
B1H20_RS17725	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B1H20_RS17735	COG0477	Major facilitator Superfamily
B1H20_RS17750	COG3467	pyridoxamine 5'-phosphate
B1H20_RS17755	COG2353	YceI-like domain
B1H20_RS17780	COG1191	sigma factor activity
B1H20_RS17785	COG1191	sigma factor activity
B1H20_RS17820	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B1H20_RS17835	COG2234	aminopeptidase activity
B1H20_RS17870	COG0464	growth
B1H20_RS17945	COG4941	Belongs to the sigma-70 factor family
B1H20_RS18000	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
B1H20_RS18130	COG0105	UTP biosynthetic process
B1H20_RS18140	COG0494	nUDIX hydrolase
B1H20_RS18195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B1H20_RS18285	COG0151	Belongs to the GarS family
B1H20_RS18300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B1H20_RS18310	COG2197	response regulator
B1H20_RS18325	COG1131	(ABC) transporter
B1H20_RS18345	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B1H20_RS18350	COG0047	phosphoribosylformylglycinamidine synthase activity
B1H20_RS18355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B1H20_RS18365	COG1196	nuclear chromosome segregation
B1H20_RS18365	COG0739	heme binding
B1H20_RS18365	COG0741	lytic transglycosylase activity
B1H20_RS18380	COG3119	arylsulfatase activity
B1H20_RS18390	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B1H20_RS18400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B1H20_RS18425	COG1643	Atp-dependent helicase
B1H20_RS18435	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B1H20_RS18435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B1H20_RS18440	COG0785	Cytochrome C biogenesis protein
B1H20_RS18470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B1H20_RS18475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B1H20_RS18485	COG0513	Belongs to the DEAD box helicase family
B1H20_RS18495	COG0596	Alpha beta hydrolase
B1H20_RS18500	COG1366	Belongs to the anti-sigma-factor antagonist family
B1H20_RS18510	COG0596	Alpha beta hydrolase
B1H20_RS18540	COG1191	sigma factor activity
B1H20_RS18555	COG1937	Protein conserved in bacteria
B1H20_RS18570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1H20_RS18570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1H20_RS18575	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B1H20_RS18580	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B1H20_RS18605	COG0739	heme binding
B1H20_RS18605	COG0741	lytic transglycosylase activity
B1H20_RS18605	COG1196	nuclear chromosome segregation
B1H20_RS18620	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B1H20_RS18625	COG0579	oxidoreductase
B1H20_RS18650	COG1252	NADH dehydrogenase
B1H20_RS18665	COG1846	Transcriptional regulator
B1H20_RS18690	COG2197	response regulator
B1H20_RS18695	COG4585	Histidine kinase
B1H20_RS18775	COG0739	heme binding
B1H20_RS18775	COG1196	nuclear chromosome segregation
B1H20_RS18775	COG0741	lytic transglycosylase activity
B1H20_RS18780	COG0671	phosphoesterase, PA-phosphatase related
B1H20_RS18800	COG1937	Protein conserved in bacteria
B1H20_RS18810	COG0306	phosphate transporter
B1H20_RS18830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B1H20_RS18835	COG0494	nUDIX hydrolase
B1H20_RS18835	COG0406	alpha-ribazole phosphatase activity
B1H20_RS18850	COG0488	(ABC) transporter
B1H20_RS18855	COG1725	Transcriptional regulator
B1H20_RS18865	COG0456	acetyltransferase
B1H20_RS18875	COG0737	Belongs to the 5'-nucleotidase family
B1H20_RS18880	COG4106	trans-aconitate 2-methyltransferase activity
B1H20_RS18905	COG0154	amidase activity
B1H20_RS18920	COG4977	sequence-specific DNA binding
B1H20_RS18935	COG0739	heme binding
B1H20_RS18970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1H20_RS18975	COG1609	Transcriptional regulator
B1H20_RS18980	COG0745	RESPONSE REGULATOR receiver
B1H20_RS19010	COG2897	thiosulfate sulfurtransferase activity
B1H20_RS19030	COG3485	protocatechuate 3,4-dioxygenase
B1H20_RS19035	COG0735	belongs to the Fur family
B1H20_RS19045	COG1490	D-aminoacyl-tRNA deacylase activity
B1H20_RS19060	COG4552	Acetyltransferase involved in intracellular survival and related
B1H20_RS19100	COG4942	peptidase
B1H20_RS19170	COG0438	transferase activity, transferring glycosyl groups
B1H20_RS19225	COG0640	Transcriptional regulator
B1H20_RS19230	COG0798	PFAM Bile acid sodium symporter
B1H20_RS19235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B1H20_RS19245	COG0588	phosphoglycerate mutase activity
B1H20_RS19260	COG5002	protein histidine kinase activity
B1H20_RS19280	COG1329	Transcriptional regulator
B1H20_RS19285	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B1H20_RS19290	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B1H20_RS19305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H20_RS19315	COG3467	pyridoxamine 5'-phosphate
B1H20_RS19320	COG0215	cysteine-tRNA ligase activity
B1H20_RS19345	COG3842	ATPase activity
B1H20_RS19400	COG0745	RESPONSE REGULATOR receiver
B1H20_RS19450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1H20_RS19470	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B1H20_RS19490	COG2197	response regulator
B1H20_RS19495	COG4585	Histidine kinase
B1H20_RS19525	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B1H20_RS19550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B1H20_RS19560	COG1653	transport
B1H20_RS19620	COG1012	belongs to the aldehyde dehydrogenase family
B1H20_RS19655	COG0076	glutamate decarboxylase activity
B1H20_RS19660	COG0655	NAD(P)H dehydrogenase (quinone) activity
B1H20_RS19670	COG0393	Putative heavy-metal-binding
B1H20_RS19675	COG0586	Pfam SNARE associated Golgi protein
B1H20_RS19685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B1H20_RS19690	COG2027	D-alanyl-D-alanine carboxypeptidase
B1H20_RS19700	COG0037	tRNA processing
B1H20_RS19715	COG0302	gtp cyclohydrolase
B1H20_RS19730	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B1H20_RS19745	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B1H20_RS19745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B1H20_RS19755	COG1125	glycine betaine transport
B1H20_RS19755	COG0517	IMP dehydrogenase activity
B1H20_RS19760	COG1174	glycine betaine transport
B1H20_RS19765	COG1174	glycine betaine transport
B1H20_RS19780	COG0649	NAD binding
B1H20_RS19795	COG2197	response regulator
B1H20_RS19800	COG1660	Displays ATPase and GTPase activities
B1H20_RS19825	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B1H20_RS19830	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B1H20_RS19840	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B1H20_RS19860	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B1H20_RS19895	COG0739	heme binding
B1H20_RS19900	COG2205	protein histidine kinase activity
B1H20_RS19905	COG0745	RESPONSE REGULATOR receiver
B1H20_RS19915	COG1595	DNA-templated transcription, initiation
B1H20_RS19920	COG1194	a g-specific adenine glycosylase
B1H20_RS19930	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
B1H20_RS19950	COG0248	Ppx GppA phosphatase
B1H20_RS19955	COG1082	Xylose isomerase domain protein TIM barrel
B1H20_RS19965	COG0129	dihydroxy-acid dehydratase activity
B1H20_RS19970	COG0515	serine threonine protein kinase
B1H20_RS19970	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1H20_RS19975	COG4991	sh3 domain protein
B1H20_RS19985	COG1129	ABC transporter
B1H20_RS19985	COG0842	Transport permease protein
B1H20_RS19995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B1H20_RS20020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B1H20_RS20080	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B1H20_RS20085	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B1H20_RS20090	COG0181	hydroxymethylbilane synthase activity
B1H20_RS20095	COG1648	precorrin-2 dehydrogenase activity
B1H20_RS20095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B1H20_RS20100	COG0113	porphobilinogen synthase activity
B1H20_RS20135	COG2318	DinB family
B1H20_RS20165	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B1H20_RS20190	COG2161	toxin-antitoxin pair type II binding
B1H20_RS20230	COG0577	efflux transmembrane transporter activity
B1H20_RS20230	COG1136	(ABC) transporter
B1H20_RS20235	COG1136	(ABC) transporter
B1H20_RS20255	COG0745	RESPONSE REGULATOR receiver
B1H20_RS20260	COG2205	protein histidine kinase activity
B1H20_RS20280	COG1309	transcriptional regulator
B1H20_RS20345	COG1335	isochorismatase
B1H20_RS20360	COG2318	DinB family
B1H20_RS20370	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B1H20_RS20400	COG2205	protein histidine kinase activity
B1H20_RS20405	COG0277	FAD linked oxidase domain protein
B1H20_RS20405	COG0247	lactate metabolic process
B1H20_RS20410	COG0583	DNA-binding transcription factor activity
B1H20_RS20415	COG5006	permease, DMT superfamily
B1H20_RS20425	COG1051	belongs to the nudix hydrolase family
B1H20_RS20440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1H20_RS20455	COG0318	PFAM AMP-dependent synthetase and ligase
B1H20_RS20460	COG1024	Enoyl-CoA hydratase
B1H20_RS20495	COG1396	sequence-specific DNA binding
B1H20_RS20515	COG0259	pyridoxamine-phosphate oxidase activity
B1H20_RS20525	COG4821	SIS domain
B1H20_RS20540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B1H20_RS20590	COG0604	alcohol dehydrogenase
B1H20_RS20605	COG2267	carboxylic ester hydrolase activity
B1H20_RS20620	COG1366	Belongs to the anti-sigma-factor antagonist family
B1H20_RS20635	COG0318	PFAM AMP-dependent synthetase and ligase
B1H20_RS20645	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS20650	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS20670	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS20675	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS20715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B1H20_RS20720	COG1024	Enoyl-CoA hydratase
B1H20_RS20740	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1H20_RS20750	COG2072	flavoprotein involved in K transport
B1H20_RS20765	COG2124	cytochrome p450
B1H20_RS20780	COG0501	Belongs to the peptidase M48B family
B1H20_RS20805	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS20815	COG1309	transcriptional regulator
B1H20_RS20840	COG1024	Enoyl-CoA hydratase
B1H20_RS20855	COG0318	PFAM AMP-dependent synthetase and ligase
B1H20_RS20885	COG0789	Transcriptional regulator
B1H20_RS20890	COG1278	Cold shock
B1H20_RS20895	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
B1H20_RS20905	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
B1H20_RS20930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1H20_RS20935	COG4521	taurine ABC transporter
B1H20_RS20945	COG2175	clavaminate synthase activity
B1H20_RS20950	COG2226	methyltransferase
B1H20_RS21010	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H20_RS21015	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H20_RS21020	COG0649	NAD binding
B1H20_RS21030	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B1H20_RS21035	COG1034	ATP synthesis coupled electron transport
B1H20_RS21040	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B1H20_RS21045	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H20_RS21050	COG0839	Belongs to the complex I subunit 6 family
B1H20_RS21055	COG0713	ATP synthesis coupled electron transport
B1H20_RS21060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B1H20_RS21070	COG1007	ATP synthesis coupled electron transport
B1H20_RS21075	COG0514	ATP-dependent DNA helicase (RecQ)
B1H20_RS21110	COG3104	oligopeptide transport
B1H20_RS21115	COG0142	geranyltranstransferase activity
B1H20_RS21140	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B1H20_RS21140	COG0515	serine threonine protein kinase
B1H20_RS21170	COG0561	phosphatase activity
B1H20_RS21185	COG0667	Aldo Keto reductase
B1H20_RS21270	COG0702	epimerase
B1H20_RS21275	COG1733	regulation of RNA biosynthetic process
B1H20_RS21280	COG1013	pyruvate-flavodoxin oxidoreductase activity
B1H20_RS21285	COG0674	pyruvate-flavodoxin oxidoreductase activity
B1H20_RS21285	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B1H20_RS21300	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H20_RS21305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H20_RS21310	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H20_RS21315	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B1H20_RS21320	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1H20_RS21325	COG0839	Belongs to the complex I subunit 6 family
B1H20_RS21330	COG0713	ATP synthesis coupled electron transport
B1H20_RS21345	COG1007	ATP synthesis coupled electron transport
B1H20_RS21350	COG1970	mechanosensitive ion channel activity
B1H20_RS21355	COG0501	Belongs to the peptidase M48B family
B1H20_RS21360	COG3304	Inner membrane component domain
B1H20_RS21375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B1H20_RS21380	COG1666	GTP binding
B1H20_RS21480	COG0702	epimerase
B1H20_RS21500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B1H20_RS21505	COG2030	dehydratase
B1H20_RS21520	COG0477	Major facilitator Superfamily
B1H20_RS21525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B1H20_RS21530	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B1H20_RS21535	COG0436	Aminotransferase
B1H20_RS21555	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B1H20_RS21560	COG0081	regulation of translation
B1H20_RS21570	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B1H20_RS21575	COG0222	ribosome binding
B1H20_RS21585	COG0085	RNA polymerase activity
B1H20_RS21590	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B1H20_RS21595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B1H20_RS21665	COG0739	heme binding
B1H20_RS21665	COG1196	nuclear chromosome segregation
B1H20_RS21665	COG0741	lytic transglycosylase activity
B1H20_RS21680	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B1H20_RS21685	COG0049	tRNA binding
B1H20_RS21690	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B1H20_RS21695	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B1H20_RS21700	COG4585	Histidine kinase
B1H20_RS21705	COG2197	response regulator
B1H20_RS21720	COG0051	transcription antitermination factor activity, RNA binding
B1H20_RS21725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B1H20_RS21730	COG0088	Forms part of the polypeptide exit tunnel
B1H20_RS21735	COG0089	rRNA binding
B1H20_RS21740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B1H20_RS21745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B1H20_RS21750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B1H20_RS21755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B1H20_RS21760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B1H20_RS21765	COG0255	Belongs to the universal ribosomal protein uL29 family
B1H20_RS21770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B1H20_RS21775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B1H20_RS21780	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B1H20_RS21785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B1H20_RS21790	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B1H20_RS21800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B1H20_RS21805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B1H20_RS21810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B1H20_RS21815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B1H20_RS21820	COG1841	ribosomal large subunit assembly
B1H20_RS21825	COG0200	Binds to the 23S rRNA
B1H20_RS21835	COG0563	adenylate kinase activity
B1H20_RS21845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B1H20_RS21850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B1H20_RS21855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B1H20_RS21860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B1H20_RS21865	COG0202	RNA polymerase activity
B1H20_RS21870	COG0203	ribosomal protein L17
B1H20_RS21875	COG0101	tRNA pseudouridine synthase activity
B1H20_RS21885	COG0488	(ABC) transporter
B1H20_RS21890	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B1H20_RS21895	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B1H20_RS21900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1H20_RS21910	COG1072	(Pantothenic acid kinase))
B1H20_RS21985	COG0596	Alpha beta hydrolase
B1H20_RS21995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B1H20_RS22000	COG0736	holo-[acyl-carrier-protein] synthase activity
B1H20_RS22010	COG3189	MarR family transcriptional regulator
B1H20_RS22015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B1H20_RS22025	COG0802	atpase or kinase
B1H20_RS22050	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B1H20_RS22085	COG0726	polysaccharide deacetylase
B1H20_RS22095	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B1H20_RS22110	COG2132	Multicopper oxidase
B1H20_RS22125	COG0583	DNA-binding transcription factor activity
B1H20_RS22140	COG1595	DNA-templated transcription, initiation
B1H20_RS22150	COG0516	GMP reductase activity
B1H20_RS22180	COG0515	serine threonine protein kinase
B1H20_RS22185	COG1012	belongs to the aldehyde dehydrogenase family
B1H20_RS22205	COG0519	Catalyzes the synthesis of GMP from XMP
B1H20_RS22205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B1H20_RS22215	COG4106	trans-aconitate 2-methyltransferase activity
B1H20_RS22250	COG2197	response regulator
B1H20_RS22255	COG0791	NLP P60 protein
B1H20_RS22275	COG0739	heme binding
B1H20_RS22285	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H20_RS22305	COG0714	Associated with various cellular activities
B1H20_RS22315	COG3552	Protein containing von Willebrand factor type A (VWA) domain
B1H20_RS22320	COG0045	succinate-CoA ligase (ADP-forming) activity
B1H20_RS22350	COG0138	bifunctional purine biosynthesis protein purh
B1H20_RS22365	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B1H20_RS22380	COG0039	L-malate dehydrogenase activity
B1H20_RS22390	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1H20_RS22395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1H20_RS22405	COG0754	glutathionylspermidine amidase activity
B1H20_RS22410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B1H20_RS22415	COG0180	Tryptophanyl-tRNA synthetase
B1H20_RS22435	COG1295	ribonuclease BN
B1H20_RS22445	COG1408	metallophosphoesterase
B1H20_RS22480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B1H20_RS22485	COG1053	succinate dehydrogenase
B1H20_RS22495	COG2009	succinate dehydrogenase
B1H20_RS22545	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B1H20_RS22550	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B1H20_RS22555	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
B1H20_RS22560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B1H20_RS22570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1H20_RS22585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1H20_RS22595	COG0402	S-adenosylhomocysteine deaminase activity
B1H20_RS22600	COG1335	isochorismatase
B1H20_RS22610	COG0189	ligase activity
B1H20_RS22620	COG0602	queuosine metabolic process
B1H20_RS22625	COG0302	gtp cyclohydrolase
B1H20_RS22630	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B1H20_RS22635	COG0367	asparagine synthase
B1H20_RS22655	COG0667	Aldo Keto reductase
B1H20_RS22700	COG1595	DNA-templated transcription, initiation
B1H20_RS22735	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B1H20_RS22745	COG1216	Glycosyl transferase, family 2
B1H20_RS22755	COG1083	cytidylyl-transferase
B1H20_RS22760	COG2089	acid synthase
B1H20_RS22770	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B1H20_RS22770	COG1473	amidohydrolase
B1H20_RS22775	COG1744	ABC transporter substrate-binding protein PnrA-like
B1H20_RS22780	COG3845	ABC transporter
B1H20_RS22785	COG4603	Belongs to the binding-protein-dependent transport system permease family
B1H20_RS22790	COG1079	Belongs to the binding-protein-dependent transport system permease family
B1H20_RS22810	COG1404	Belongs to the peptidase S8 family
B1H20_RS22830	COG2814	Major facilitator Superfamily
B1H20_RS22835	COG0583	DNA-binding transcription factor activity
B1H20_RS22855	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B1H20_RS22880	COG2205	protein histidine kinase activity
B1H20_RS22885	COG0745	RESPONSE REGULATOR receiver
B1H20_RS22890	COG1595	DNA-templated transcription, initiation
B1H20_RS22905	COG1012	belongs to the aldehyde dehydrogenase family
B1H20_RS22910	COG1012	belongs to the aldehyde dehydrogenase family
B1H20_RS22925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1H20_RS22955	COG4770	biotin carboxylase activity
B1H20_RS22965	COG0424	maF-like protein
B1H20_RS22975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1H20_RS22990	COG1024	Enoyl-CoA hydratase
B1H20_RS23015	COG1376	ErfK ybiS ycfS ynhG family protein
B1H20_RS23035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B1H20_RS23040	COG1396	sequence-specific DNA binding
B1H20_RS23055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B1H20_RS23060	COG0583	DNA-binding transcription factor activity
B1H20_RS23075	COG0501	Belongs to the peptidase M48B family
B1H20_RS23100	COG1595	DNA-templated transcription, initiation
B1H20_RS23105	COG0745	RESPONSE REGULATOR receiver
B1H20_RS23110	COG0784	Response regulator, receiver
B1H20_RS23110	COG5002	protein histidine kinase activity
B1H20_RS23110	COG2198	Histidine kinase
B1H20_RS23120	COG2172	sigma factor antagonist activity
B1H20_RS23125	COG1366	Belongs to the anti-sigma-factor antagonist family
B1H20_RS23130	COG1366	Belongs to the anti-sigma-factor antagonist family
B1H20_RS23140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B1H20_RS23155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B1H20_RS23165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1H20_RS23190	COG2197	response regulator
B1H20_RS23195	COG0577	efflux transmembrane transporter activity
B1H20_RS23195	COG1136	(ABC) transporter
B1H20_RS23205	COG4585	Histidine kinase
B1H20_RS23230	COG1331	Highly conserved protein containing a thioredoxin domain
B1H20_RS23240	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
B1H20_RS23250	COG0436	Aminotransferase
B1H20_RS23270	COG1733	regulation of RNA biosynthetic process
B1H20_RS23290	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
B1H20_RS23305	COG1414	Transcriptional regulator
B1H20_RS23310	COG0251	oxidation-reduction process
B1H20_RS23315	COG2610	gluconate transmembrane transporter activity
B1H20_RS23340	COG2894	cell division
B1H20_RS23370	COG3920	Histidine kinase
B1H20_RS23375	COG2197	response regulator
B1H20_RS23395	COG2885	chlorophyll binding
B1H20_RS23465	COG2226	methyltransferase
B1H20_RS23480	COG0667	Aldo Keto reductase
B1H20_RS23485	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B1H20_RS23490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B1H20_RS23505	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1H20_RS23510	COG0450	alkyl hydroperoxide reductase
B1H20_RS23525	COG1136	(ABC) transporter
B1H20_RS23545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1H20_RS23545	COG4499	WXG100 protein secretion system (Wss), protein YukC
B1H20_RS23560	COG0114	fumarate hydratase activity
B1H20_RS23570	COG1362	aminopeptidase activity
B1H20_RS23595	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B1H20_RS23595	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B1H20_RS23620	COG0778	Nitroreductase
B1H20_RS23625	COG1722	exodeoxyribonuclease VII activity
B1H20_RS23630	COG1570	exodeoxyribonuclease VII activity
B1H20_RS23640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B1H20_RS23655	COG0012	GTP binding
B1H20_RS23665	COG0477	Major facilitator Superfamily
B1H20_RS23675	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1H20_RS23775	COG0463	Glycosyl transferase, family 2
B1H20_RS23805	COG0789	Transcriptional regulator
B1H20_RS23860	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B1H20_RS23875	COG2409	Drug exporters of the RND superfamily
B1H20_RS23880	COG4585	Histidine kinase
B1H20_RS23885	COG2197	response regulator
B1H20_RS23890	COG0154	amidase activity
B1H20_RS23905	COG1217	gtp-binding protein TYPA
B1H20_RS23915	COG0601	transmembrane transport
B1H20_RS23920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H20_RS23930	COG4608	Belongs to the ABC transporter superfamily
B1H20_RS23935	COG4166	transmembrane transport
B1H20_RS23940	COG0601	transmembrane transport
B1H20_RS23945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H20_RS23955	COG4608	Belongs to the ABC transporter superfamily
B1H20_RS23970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1H20_RS23995	COG0110	maltose O-acetyltransferase activity
B1H20_RS24015	COG1132	(ABC) transporter
B1H20_RS24020	COG1132	(ABC) transporter
B1H20_RS24025	COG2197	response regulator
B1H20_RS24030	COG2912	Transglutaminase-like superfamily
B1H20_RS24060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1H20_RS24065	COG1611	Belongs to the LOG family
B1H20_RS24070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B1H20_RS24080	COG0519	Catalyzes the synthesis of GMP from XMP
B1H20_RS24085	COG1024	Enoyl-CoA hydratase
B1H20_RS24100	COG1595	DNA-templated transcription, initiation
B1H20_RS24110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1H20_RS24115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1H20_RS24150	COG0598	Magnesium transport protein CorA
B1H20_RS24165	COG2814	Major facilitator Superfamily
B1H20_RS24180	COG2095	MarC family integral membrane protein
B1H20_RS24185	COG1432	Conserved Protein
B1H20_RS24235	COG0747	negative chemotaxis
B1H20_RS24245	COG0601	transmembrane transport
B1H20_RS24295	COG0210	DNA helicase
B1H20_RS24335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B1H20_RS24390	COG3480	Lon protease (S16) C-terminal proteolytic domain
B1H20_RS24400	COG1615	UPF0182 protein
B1H20_RS24425	COG0753	catalase activity
B1H20_RS24435	COG0483	inositol monophosphate 1-phosphatase activity
B1H20_RS24445	COG2076	Multidrug Resistance protein
B1H20_RS24455	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B1H20_RS24465	COG2135	peptidase activity
B1H20_RS24475	COG1595	DNA-templated transcription, initiation
B1H20_RS24480	COG5662	AntiSigma factor
B1H20_RS24490	COG0242	peptide deformylase activity
B1H20_RS24525	COG1966	Carbon starvation protein
B1H20_RS24530	COG2188	Transcriptional regulator
B1H20_RS24535	COG2182	Extracellular solute-binding protein
B1H20_RS24540	COG1175	transmembrane transport
B1H20_RS24545	COG0395	ABC-type sugar transport system, permease component
B1H20_RS24550	COG1472	Belongs to the glycosyl hydrolase 3 family
B1H20_RS24555	COG0363	glucosamine-6-phosphate deaminase activity
B1H20_RS24560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B1H20_RS24575	COG1597	lipid kinase activity
B1H20_RS24615	COG1959	2 iron, 2 sulfur cluster binding
B1H20_RS24620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1H20_RS24625	COG0142	geranyltranstransferase activity
B1H20_RS24690	COG2197	response regulator
B1H20_RS24695	COG4585	Histidine kinase
B1H20_RS24715	COG1695	Transcriptional regulator
B1H20_RS24775	COG4106	trans-aconitate 2-methyltransferase activity
B1H20_RS24780	COG1595	DNA-templated transcription, initiation
B1H20_RS24790	COG1126	abc transporter atp-binding protein
B1H20_RS24795	COG0765	amino acid transport
B1H20_RS24800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1H20_RS24805	COG0281	malic enzyme
B1H20_RS24810	COG0604	alcohol dehydrogenase
B1H20_RS24830	COG0542	response to heat
B1H20_RS24855	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1H20_RS24855	COG0567	Dehydrogenase, E1 component
B1H20_RS24865	COG2205	protein histidine kinase activity
B1H20_RS24870	COG0745	RESPONSE REGULATOR receiver
B1H20_RS24880	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B1H20_RS24885	COG0726	polysaccharide deacetylase
B1H20_RS24905	COG5002	protein histidine kinase activity
B1H20_RS24990	COG2205	protein histidine kinase activity
B1H20_RS25010	COG3285	dna ligase
B1H20_RS25010	COG1793	dna ligase
B1H20_RS25015	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B1H20_RS25020	COG0515	serine threonine protein kinase
B1H20_RS25030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B1H20_RS25125	COG0018	arginyl-trna synthetase
B1H20_RS25130	COG0019	diaminopimelate decarboxylase activity
B1H20_RS25135	COG0460	homoserine dehydrogenase
B1H20_RS25140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B1H20_RS25145	COG0083	homoserine kinase activity
B1H20_RS25155	COG1316	TRANSCRIPTIONal
B1H20_RS25160	COG0254	rRNA binding
B1H20_RS25165	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B1H20_RS25170	COG2890	protein-(glutamine-N5) methyltransferase activity
B1H20_RS25180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B1H20_RS25185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B1H20_RS25210	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B1H20_RS25215	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B1H20_RS25220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B1H20_RS25225	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B1H20_RS25230	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B1H20_RS25235	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B1H20_RS25240	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B1H20_RS25255	COG2197	response regulator
B1H20_RS25260	COG4585	Histidine kinase
B1H20_RS25290	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H20_RS25305	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
B1H20_RS25340	COG1131	(ABC) transporter
B1H20_RS25360	COG0183	Belongs to the thiolase family
B1H20_RS25375	COG0745	RESPONSE REGULATOR receiver
B1H20_RS25380	COG5000	phosphorelay sensor kinase activity
B1H20_RS25380	COG5002	protein histidine kinase activity
B1H20_RS25450	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H20_RS25450	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H20_RS25500	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B1H20_RS25505	COG0280	phosphate acetyltransferase
B1H20_RS25505	COG0857	belongs to the CobB CobQ family
B1H20_RS25510	COG0205	6-phosphofructokinase activity
B1H20_RS25520	COG4565	transcriptional regulatory protein
B1H20_RS25525	COG3290	protein histidine kinase activity
B1H20_RS25530	COG1301	dicarboxylic acid transport
B1H20_RS25555	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B1H20_RS25565	COG0366	Alpha amylase catalytic
B1H20_RS25570	COG0366	Alpha amylase catalytic
B1H20_RS25575	COG0058	SHG alpha-glucan phosphorylase activity
B1H20_RS25590	COG0387	Pfam Sodium calcium exchanger
B1H20_RS25610	COG1742	UPF0060 membrane protein
B1H20_RS25615	COG1132	(ABC) transporter
B1H20_RS25620	COG1132	(ABC) transporter
B1H20_RS25625	COG1131	(ABC) transporter
B1H20_RS25640	COG2197	response regulator
B1H20_RS25690	COG0515	serine threonine protein kinase
B1H20_RS25785	COG0823	Involved in the tonB-independent uptake of proteins
B1H20_RS25785	COG1506	peptidase
B1H20_RS25795	COG0464	growth
B1H20_RS25815	COG1760	l-serine dehydratase
B1H20_RS25820	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B1H20_RS25825	COG0509	glycine decarboxylation via glycine cleavage system
B1H20_RS25830	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B1H20_RS25850	COG0747	negative chemotaxis
B1H20_RS25855	COG0601	transmembrane transport
B1H20_RS25860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H20_RS25870	COG4608	Belongs to the ABC transporter superfamily
B1H20_RS25875	COG2860	membrane
B1H20_RS25885	COG2378	regulation of single-species biofilm formation
B1H20_RS25910	COG0482	sulfurtransferase activity
B1H20_RS25930	COG4221	oxidoreductase activity
B1H20_RS25940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B1H20_RS25950	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B1H20_RS25955	COG0154	amidase activity
B1H20_RS25965	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B1H20_RS25970	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B1H20_RS25980	COG2409	Drug exporters of the RND superfamily
B1H20_RS26000	COG2197	response regulator
B1H20_RS26010	COG2133	pyrroloquinoline quinone binding
B1H20_RS26015	COG0667	Aldo Keto reductase
B1H20_RS26025	COG5001	Diguanylate cyclase
B1H20_RS26025	COG3300	MHYT domain
B1H20_RS26035	COG0440	acetolactate synthase activity
B1H20_RS26040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B1H20_RS26045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1H20_RS26065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B1H20_RS26075	COG2508	Transcriptional regulator
B1H20_RS26080	COG0506	proline dehydrogenase activity
B1H20_RS26085	COG1012	belongs to the aldehyde dehydrogenase family
B1H20_RS26090	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
B1H20_RS26090	COG0778	Nitroreductase
B1H20_RS26105	COG0473	3-isopropylmalate dehydrogenase activity
B1H20_RS26110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B1H20_RS26120	COG2957	Belongs to the agmatine deiminase family
B1H20_RS26130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B1H20_RS26135	COG1472	Belongs to the glycosyl hydrolase 3 family
B1H20_RS26145	COG0542	response to heat
B1H20_RS26175	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B1H20_RS26190	COG3708	Transcriptional regulator
B1H20_RS26190	COG2207	Transcriptional regulator
B1H20_RS26215	COG0492	ferredoxin-NADP+ reductase activity
B1H20_RS26260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS26265	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS26270	COG1120	ATPase activity
B1H20_RS26275	COG4607	ABC-type enterochelin transport system periplasmic component
B1H20_RS26280	COG2353	YceI-like domain
B1H20_RS26300	COG0366	Alpha amylase catalytic
B1H20_RS26300	COG1470	cell adhesion involved in biofilm formation
B1H20_RS26305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1H20_RS26325	COG2018	Roadblock/LC7 domain
B1H20_RS26345	COG2018	Roadblock/LC7 domain
B1H20_RS26350	COG5002	protein histidine kinase activity
B1H20_RS26360	COG0179	Fumarylacetoacetate (FAA) hydrolase
B1H20_RS26365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B1H20_RS26410	COG1414	Transcriptional regulator
B1H20_RS26415	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B1H20_RS26420	COG0066	3-isopropylmalate dehydratase activity
B1H20_RS26430	COG0776	regulation of translation
B1H20_RS26440	COG1920	GTP binding
B1H20_RS26450	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B1H20_RS26455	COG1181	Belongs to the D-alanine--D-alanine ligase family
B1H20_RS26475	COG0351	phosphomethylpyrimidine kinase
B1H20_RS26480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B1H20_RS26485	COG1461	Dihydroxyacetone kinase
B1H20_RS26495	COG0742	ribosomal rna small subunit methyltransferase
B1H20_RS26500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B1H20_RS26515	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B1H20_RS26520	COG0571	ribonuclease III activity
B1H20_RS26525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B1H20_RS26530	COG1733	regulation of RNA biosynthetic process
B1H20_RS26535	COG2340	Cysteine-rich secretory protein family
B1H20_RS26540	COG1254	Belongs to the acylphosphatase family
B1H20_RS26550	COG1196	nuclear chromosome segregation
B1H20_RS26555	COG0477	Major facilitator Superfamily
B1H20_RS26590	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B1H20_RS26610	COG0228	four-way junction DNA binding
B1H20_RS26615	COG1837	Belongs to the UPF0109 family
B1H20_RS26620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B1H20_RS26625	COG0336	Belongs to the RNA methyltransferase TrmD family
B1H20_RS26630	COG0335	large ribosomal subunit rRNA binding
B1H20_RS26645	COG0681	Belongs to the peptidase S26 family
B1H20_RS26655	COG1051	belongs to the nudix hydrolase family
B1H20_RS26665	COG0792	nuclease activity
B1H20_RS26680	COG1191	sigma factor activity
B1H20_RS26695	COG0052	Belongs to the universal ribosomal protein uS2 family
B1H20_RS26700	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B1H20_RS26705	COG0528	UMP kinase activity
B1H20_RS26710	COG0233	cytoplasmic translational termination
B1H20_RS26715	COG0575	Belongs to the CDS family
B1H20_RS26720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B1H20_RS26735	COG3842	ATPase activity
B1H20_RS26750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1H20_RS26760	COG1012	belongs to the aldehyde dehydrogenase family
B1H20_RS26785	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B1H20_RS26825	COG1595	DNA-templated transcription, initiation
B1H20_RS26850	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B1H20_RS26855	COG3842	ATPase activity
B1H20_RS26860	COG1176	ABC-type spermidine putrescine transport system, permease component I
B1H20_RS26865	COG1177	transmembrane transport
B1H20_RS26870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1H20_RS26900	COG2508	Transcriptional regulator
B1H20_RS26915	COG1012	belongs to the aldehyde dehydrogenase family
B1H20_RS26925	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B1H20_RS26930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B1H20_RS26935	COG0750	zinc metalloprotease
B1H20_RS26940	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B1H20_RS26955	COG0442	prolyl-tRNA aminoacylation
B1H20_RS26975	COG0779	Required for maturation of 30S ribosomal subunits
B1H20_RS26990	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B1H20_RS27000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B1H20_RS27005	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B1H20_RS27035	COG4608	Belongs to the ABC transporter superfamily
B1H20_RS27045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H20_RS27050	COG0601	transmembrane transport
B1H20_RS27055	COG0747	negative chemotaxis
B1H20_RS27060	COG0455	bacterial-type flagellum organization
B1H20_RS27080	COG3266	domain, Protein
B1H20_RS27085	COG1404	Belongs to the peptidase S8 family
B1H20_RS27100	COG1404	Belongs to the peptidase S8 family
B1H20_RS27115	COG1674	ftsk spoiiie
B1H20_RS27125	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B1H20_RS27130	COG1185	polyribonucleotide nucleotidyltransferase activity
B1H20_RS27135	COG0612	Peptidase, M16
B1H20_RS27140	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B1H20_RS27160	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
B1H20_RS27165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1H20_RS27170	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B1H20_RS27205	COG2205	protein histidine kinase activity
B1H20_RS27205	COG3437	response regulator, receiver
B1H20_RS27205	COG3850	Histidine kinase
B1H20_RS27205	COG4999	Histidine kinase
B1H20_RS27215	COG1674	ftsk spoiiie
B1H20_RS27225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B1H20_RS27235	COG1058	Belongs to the CinA family
B1H20_RS27235	COG1546	Belongs to the CinA family
B1H20_RS27240	COG1396	sequence-specific DNA binding
B1H20_RS27245	COG0783	Belongs to the Dps family
B1H20_RS27260	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS27265	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B1H20_RS27270	COG1201	RNA secondary structure unwinding
B1H20_RS27275	COG1917	Cupin 2, conserved barrel domain protein
B1H20_RS27275	COG2207	Transcriptional regulator
B1H20_RS27305	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B1H20_RS27335	COG0765	amino acid transport
B1H20_RS27340	COG0765	amino acid transport
B1H20_RS27345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1H20_RS27350	COG1126	abc transporter atp-binding protein
B1H20_RS27360	COG2205	protein histidine kinase activity
B1H20_RS27365	COG2358	TRAP transporter, solute receptor (TAXI family
B1H20_RS27370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B1H20_RS27385	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B1H20_RS27395	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B1H20_RS27405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B1H20_RS27415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B1H20_RS27450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B1H20_RS27455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B1H20_RS27460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B1H20_RS27475	COG0588	phosphoglycerate mutase activity
B1H20_RS27490	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B1H20_RS27525	COG2186	Transcriptional regulator
B1H20_RS27530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B1H20_RS27555	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1H20_RS27560	COG4565	transcriptional regulatory protein
B1H20_RS27565	COG3290	protein histidine kinase activity
B1H20_RS27570	COG0372	Belongs to the citrate synthase family
B1H20_RS27575	COG0372	Belongs to the citrate synthase family
B1H20_RS27585	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B1H20_RS27590	COG0612	Peptidase, M16
B1H20_RS27605	COG1802	Transcriptional regulator
B1H20_RS27610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1H20_RS27615	COG0045	succinate-CoA ligase (ADP-forming) activity
B1H20_RS27615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1H20_RS27615	COG1042	CoA-binding domain protein
B1H20_RS27630	COG1435	thymidine kinase activity
B1H20_RS27670	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B1H20_RS27680	COG0745	RESPONSE REGULATOR receiver
B1H20_RS27685	COG2205	protein histidine kinase activity
B1H20_RS27710	COG0756	dUTP diphosphatase activity
B1H20_RS27720	COG1136	(ABC) transporter
B1H20_RS27720	COG4591	ABC-type transport system involved in lipoprotein release permease component
B1H20_RS27750	COG0569	domain protein
B1H20_RS27755	COG0531	amino acid
B1H20_RS27760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B1H20_RS27790	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B1H20_RS27795	COG4552	Acetyltransferase involved in intracellular survival and related
B1H20_RS27815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1H20_RS27860	COG2814	Major facilitator Superfamily
B1H20_RS27875	COG0596	Alpha beta hydrolase
B1H20_RS27895	COG0446	pyridine nucleotide-disulphide oxidoreductase
B1H20_RS27905	COG3938	Belongs to the proline racemase family
B1H20_RS27915	COG2423	ornithine cyclodeaminase activity
B1H20_RS27920	COG1802	Transcriptional regulator
B1H20_RS27925	COG0006	proline dipeptidase activity
B1H20_RS27935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H20_RS27940	COG0601	transmembrane transport
B1H20_RS27955	COG3291	Pkd domain containing protein
B1H20_RS27965	COG1280	lysine exporter protein (LysE YggA)
B1H20_RS27970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1H20_RS27975	COG3046	protein related to deoxyribodipyrimidine photolyase
B1H20_RS28005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS28010	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS28020	COG0586	Pfam SNARE associated Golgi protein
B1H20_RS28025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B1H20_RS28030	COG1349	DNA-binding transcription factor activity
B1H20_RS28035	COG1799	cell septum assembly
B1H20_RS28055	COG2040	homocysteine
B1H20_RS28065	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B1H20_RS28075	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B1H20_RS28080	COG0531	amino acid
B1H20_RS28090	COG1024	Enoyl-CoA hydratase
B1H20_RS28130	COG2111	Na H antiporter
B1H20_RS28130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B1H20_RS28135	COG1006	Multisubunit Na H antiporter MnhC subunit
B1H20_RS28140	COG0651	ATP synthesis coupled electron transport
B1H20_RS28155	COG1320	monovalent cation:proton antiporter activity
B1H20_RS28170	COG0297	glycogen (starch) synthase activity
B1H20_RS28175	COG0489	protein tyrosine kinase activity
B1H20_RS28215	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
B1H20_RS28220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B1H20_RS28225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B1H20_RS28240	COG2197	response regulator
B1H20_RS28245	COG1063	alcohol dehydrogenase
B1H20_RS28260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B1H20_RS28270	COG1129	ABC transporter
B1H20_RS28300	COG0477	Major facilitator Superfamily
B1H20_RS28305	COG3903	Transcriptional regulator
B1H20_RS28305	COG3629	intracellular signal transduction
B1H20_RS28310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H20_RS28320	COG0300	oxidoreductase activity
B1H20_RS28330	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS28355	COG0475	glutathione-regulated potassium exporter activity
B1H20_RS28375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H20_RS28395	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B1H20_RS28425	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B1H20_RS28430	COG0494	nUDIX hydrolase
B1H20_RS28435	COG0494	nUDIX hydrolase
B1H20_RS28455	COG0588	phosphoglycerate mutase activity
B1H20_RS28465	COG1653	transport
B1H20_RS28470	COG1175	transmembrane transport
B1H20_RS28475	COG0395	ABC-type sugar transport system, permease component
B1H20_RS28480	COG1940	carbohydrate kinase activity
B1H20_RS28485	COG4213	ABC transporter substrate-binding protein
B1H20_RS28495	COG4214	carbohydrate transport
B1H20_RS28500	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B1H20_RS28505	COG0531	amino acid
B1H20_RS28525	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1H20_RS28530	COG0438	transferase activity, transferring glycosyl groups
B1H20_RS28545	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H20_RS28545	COG1024	Enoyl-CoA hydratase
B1H20_RS28550	COG0183	Belongs to the thiolase family
B1H20_RS28575	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B1H20_RS28590	COG0745	RESPONSE REGULATOR receiver
B1H20_RS28595	COG0446	pyridine nucleotide-disulphide oxidoreductase
B1H20_RS28605	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B1H20_RS28610	COG3253	May function as heme-dependent peroxidase
B1H20_RS28625	COG3220	belongs to the UPF0276 family
B1H20_RS28640	COG4152	abc transporter atp-binding protein
B1H20_RS28690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B1H20_RS28695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B1H20_RS28825	COG1063	alcohol dehydrogenase
B1H20_RS28830	COG0156	8-amino-7-oxononanoate synthase activity
B1H20_RS28835	COG0583	DNA-binding transcription factor activity
B1H20_RS28845	COG0346	lactoylglutathione lyase activity
B1H20_RS28850	COG1072	(Pantothenic acid kinase))
B1H20_RS28870	COG2723	6-phospho-beta-galactosidase activity
B1H20_RS28925	COG1175	transmembrane transport
B1H20_RS28945	COG1404	Belongs to the peptidase S8 family
B1H20_RS28965	COG1132	(ABC) transporter
B1H20_RS28970	COG1132	(ABC) transporter
B1H20_RS28975	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B1H20_RS28980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS28985	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS28990	COG1120	ATPase activity
B1H20_RS28995	COG2226	methyltransferase
B1H20_RS29005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1H20_RS29010	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B1H20_RS29030	COG0529	Catalyzes the synthesis of activated sulfate
B1H20_RS29035	COG0175	sulfate reduction
B1H20_RS29070	COG3844	kynureninase activity
B1H20_RS29075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B1H20_RS29090	COG1917	Cupin 2, conserved barrel domain protein
B1H20_RS29115	COG0583	DNA-binding transcription factor activity
B1H20_RS29140	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H20_RS29145	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B1H20_RS29150	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B1H20_RS29155	COG0583	DNA-binding transcription factor activity
B1H20_RS29160	COG0183	Belongs to the thiolase family
B1H20_RS29210	COG1162	GTPase activity
B1H20_RS29230	COG1404	Belongs to the peptidase S8 family
B1H20_RS29240	COG0028	Belongs to the TPP enzyme family
B1H20_RS29260	COG1802	Transcriptional regulator
B1H20_RS29285	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B1H20_RS29290	COG2252	PERMEase
B1H20_RS29295	COG3608	succinylglutamate desuccinylase aspartoacylase
B1H20_RS29295	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B1H20_RS29320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H20_RS29355	COG0435	Glutathione S-transferase
B1H20_RS29370	COG2197	response regulator
B1H20_RS29375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1H20_RS29380	COG0318	PFAM AMP-dependent synthetase and ligase
B1H20_RS29400	COG3960	tartronate-semialdehyde synthase activity
B1H20_RS29430	COG0753	catalase activity
B1H20_RS29435	COG2084	Dehydrogenase
B1H20_RS29440	COG3622	Belongs to the hyi family
B1H20_RS29445	COG2706	6-phosphogluconolactonase activity
B1H20_RS29465	COG2351	hydroxyisourate hydrolase activity
B1H20_RS29475	COG2233	PERMEase
B1H20_RS29485	COG2233	PERMEase
B1H20_RS29515	COG1288	antiporter activity
B1H20_RS29545	COG0242	peptide deformylase activity
B1H20_RS29550	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B1H20_RS29565	COG2197	response regulator
B1H20_RS29585	COG1414	Transcriptional regulator
B1H20_RS29590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B1H20_RS29595	COG4266	Belongs to the allantoicase family
B1H20_RS29605	COG0656	L-ascorbic acid biosynthetic process
B1H20_RS29610	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS29630	COG2197	response regulator
B1H20_RS29645	COG0673	inositol 2-dehydrogenase activity
B1H20_RS29650	COG2188	Transcriptional regulator
B1H20_RS29665	COG1129	ABC transporter
B1H20_RS29670	COG1940	carbohydrate kinase activity
B1H20_RS29680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1H20_RS29685	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B1H20_RS29700	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS29720	COG1126	abc transporter atp-binding protein
B1H20_RS29725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1H20_RS29730	COG0765	amino acid transport
B1H20_RS29735	COG0765	amino acid transport
B1H20_RS29750	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H20_RS29750	COG1024	Enoyl-CoA hydratase
B1H20_RS29755	COG0183	Belongs to the thiolase family
B1H20_RS29775	COG1012	belongs to the aldehyde dehydrogenase family
B1H20_RS29785	COG1309	transcriptional regulator
B1H20_RS29790	COG0318	PFAM AMP-dependent synthetase and ligase
B1H20_RS29795	COG0405	Gamma-glutamyltransferase
B1H20_RS29830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B1H20_RS29920	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS29940	COG0463	Glycosyl transferase, family 2
B1H20_RS29950	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B1H20_RS29965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H20_RS29980	COG0175	sulfate reduction
B1H20_RS29985	COG2895	sulfate adenylyltransferase (ATP) activity
B1H20_RS30030	COG0626	cystathionine gamma-synthase activity
B1H20_RS30045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H20_RS30100	COG0095	Lipoate-protein ligase
B1H20_RS30120	COG1024	Enoyl-CoA hydratase
B1H20_RS30125	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS30145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B1H20_RS30160	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1H20_RS30200	COG1024	Enoyl-CoA hydratase
B1H20_RS30205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H20_RS30235	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS30240	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS30245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1H20_RS30250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1H20_RS30260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H20_RS30270	COG1131	(ABC) transporter
B1H20_RS30275	COG1024	Enoyl-CoA hydratase
B1H20_RS30285	COG0483	inositol monophosphate 1-phosphatase activity
B1H20_RS30310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B1H20_RS30340	COG1929	Belongs to the glycerate kinase type-1 family
B1H20_RS30375	COG0688	phosphatidylethanolamine metabolic process
B1H20_RS30380	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS30390	COG2301	Belongs to the HpcH HpaI aldolase family
B1H20_RS30395	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H20_RS30395	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1H20_RS30400	COG0604	alcohol dehydrogenase
B1H20_RS30420	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H20_RS30430	COG0596	Alpha beta hydrolase
B1H20_RS30460	COG0583	DNA-binding transcription factor activity
B1H20_RS30465	COG0667	Aldo Keto reductase
B1H20_RS30485	COG2362	D-Aminopeptidase
B1H20_RS30490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1H20_RS30500	COG1619	proteins homologs of microcin C7 resistance protein MccF
B1H20_RS30555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B1H20_RS30570	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1H20_RS30570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1H20_RS30580	COG2154	pterin-4-alpha-carbinolamine dehydratase
B1H20_RS30590	COG0702	epimerase
B1H20_RS30600	COG4106	trans-aconitate 2-methyltransferase activity
B1H20_RS30605	COG0300	oxidoreductase activity
B1H20_RS30635	COG0656	L-ascorbic acid biosynthetic process
B1H20_RS30650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B1H20_RS30655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1H20_RS30665	COG1129	ABC transporter
B1H20_RS30670	COG1172	Belongs to the binding-protein-dependent transport system permease family
B1H20_RS30675	COG1879	ABC-type sugar transport system periplasmic component
B1H20_RS30680	COG0673	inositol 2-dehydrogenase activity
B1H20_RS30700	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B1H20_RS30715	COG0084	hydrolase, TatD family'
B1H20_RS30795	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS30795	COG0318	PFAM AMP-dependent synthetase and ligase
B1H20_RS30795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H20_RS30795	COG3321	synthase
B1H20_RS30795	COG0300	oxidoreductase activity
B1H20_RS30800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B1H20_RS30815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H20_RS30820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H20_RS30825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H20_RS30825	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B1H20_RS30825	COG3321	synthase
B1H20_RS30845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H20_RS30855	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS30880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1H20_RS30885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H20_RS30890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B1H20_RS30895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B1H20_RS30900	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS30920	COG0477	Major facilitator Superfamily
B1H20_RS30925	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS30935	COG1129	ABC transporter
B1H20_RS30940	COG1879	ABC-type sugar transport system periplasmic component
B1H20_RS30945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1H20_RS30950	COG1869	D-ribose catabolic process
B1H20_RS30960	COG0714	Associated with various cellular activities
B1H20_RS30975	COG3568	Endonuclease Exonuclease Phosphatase
B1H20_RS30990	COG5002	protein histidine kinase activity
B1H20_RS30995	COG0745	RESPONSE REGULATOR receiver
B1H20_RS31025	COG1012	belongs to the aldehyde dehydrogenase family
B1H20_RS31035	COG4175	Glycine betaine
B1H20_RS31035	COG0517	IMP dehydrogenase activity
B1H20_RS31040	COG4176	ABC-type proline glycine betaine transport system permease component
B1H20_RS31050	COG2124	cytochrome p450
B1H20_RS31080	COG0488	(ABC) transporter
B1H20_RS31090	COG1070	Carbohydrate kinase
B1H20_RS31100	COG1940	carbohydrate kinase activity
B1H20_RS31150	COG2124	cytochrome p450
B1H20_RS31155	COG1486	melibiose metabolic process
B1H20_RS31185	COG3012	SEC-C Motif Domain Protein
B1H20_RS31210	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS31255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B1H20_RS31280	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B1H20_RS31320	COG2326	polyphosphate kinase activity
B1H20_RS31325	COG1793	dna ligase
B1H20_RS31375	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B1H20_RS31390	COG0488	(ABC) transporter
B1H20_RS31415	COG1515	deoxyribonuclease V activity
B1H20_RS31420	COG3268	Saccharopine dehydrogenase
B1H20_RS31425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1H20_RS31430	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS31435	COG0183	Belongs to the thiolase family
B1H20_RS31440	COG1024	Enoyl-CoA hydratase
B1H20_RS31440	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1H20_RS31445	COG0789	Transcriptional regulator
B1H20_RS31470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B1H20_RS31485	COG0488	(ABC) transporter
B1H20_RS31490	COG2226	methyltransferase
B1H20_RS31505	COG4977	sequence-specific DNA binding
B1H20_RS31515	COG1024	Enoyl-CoA hydratase
B1H20_RS31530	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B1H20_RS31565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B1H20_RS31585	COG1134	teichoic acid transport
B1H20_RS31590	COG1562	ergosterol biosynthetic process
B1H20_RS31600	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B1H20_RS31610	COG1657	PFAM Prenyltransferase squalene oxidase
B1H20_RS31645	COG2755	lipolytic protein G-D-S-L family
B1H20_RS31655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B1H20_RS31695	COG3467	pyridoxamine 5'-phosphate
B1H20_RS31705	COG0789	Transcriptional regulator
B1H20_RS31760	COG3958	Transketolase
B1H20_RS31765	COG3959	Transketolase, thiamine diphosphate binding domain
B1H20_RS31775	COG0318	PFAM AMP-dependent synthetase and ligase
B1H20_RS31785	COG1733	regulation of RNA biosynthetic process
B1H20_RS31810	COG3511	phospholipase C
B1H20_RS31820	COG2197	response regulator
B1H20_RS31825	COG3851	Histidine kinase
B1H20_RS31865	COG2197	response regulator
B1H20_RS31895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H20_RS31900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B1H20_RS31905	COG2423	ornithine cyclodeaminase activity
B1H20_RS31910	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS31950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1H20_RS31965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B1H20_RS31990	COG1280	lysine exporter protein (LysE YggA)
B1H20_RS32045	COG1902	pentaerythritol trinitrate reductase activity
B1H20_RS32045	COG0446	pyridine nucleotide-disulphide oxidoreductase
B1H20_RS32055	COG2409	Drug exporters of the RND superfamily
B1H20_RS32060	COG1846	Transcriptional regulator
B1H20_RS32110	COG2130	NADP-dependent
B1H20_RS32120	COG4948	Mandelate Racemase Muconate Lactonizing
B1H20_RS32125	COG0395	ABC-type sugar transport system, permease component
B1H20_RS32130	COG1175	transmembrane transport
B1H20_RS32145	COG2226	methyltransferase
B1H20_RS32160	COG3647	Membrane
B1H20_RS32165	COG2188	Transcriptional regulator
B1H20_RS32170	COG1742	UPF0060 membrane protein
B1H20_RS32185	COG1794	racemase activity, acting on amino acids and derivatives
B1H20_RS32225	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B1H20_RS32240	COG0019	diaminopimelate decarboxylase activity
B1H20_RS32245	COG2837	iron assimilation
B1H20_RS32250	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B1H20_RS32265	COG1119	ATPase activity
B1H20_RS32275	COG1595	DNA-templated transcription, initiation
B1H20_RS32305	COG0596	Alpha beta hydrolase
B1H20_RS32315	COG1028	Short-chain dehydrogenase reductase Sdr
B1H20_RS32325	COG1652	LysM domain
B1H20_RS32350	COG2208	phosphoserine phosphatase activity
B1H20_RS32360	COG0784	Response regulator, receiver
B1H20_RS32365	COG4251	negative regulation of phosphorylation
B1H20_RS32370	COG2201	protein-glutamate methylesterase activity
B1H20_RS32375	COG1191	sigma factor activity
B1H20_RS32410	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B1H20_RS32425	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1H20_RS32430	COG3275	phosphorelay sensor kinase activity
B1H20_RS32500	COG0583	DNA-binding transcription factor activity
B1H20_RS32510	COG1053	succinate dehydrogenase
B1H20_RS32515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B1H20_RS32525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1H20_RS32535	COG3360	Dodecin
B1H20_RS32540	COG1653	transport
B1H20_RS32555	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B1H20_RS32560	COG0121	glutamine amidotransferase
B1H20_RS32565	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B1H20_RS32585	COG1609	Transcriptional regulator
B1H20_RS32595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1H20_RS32600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B1H20_RS32625	COG0714	Associated with various cellular activities
B1H20_RS32645	COG1191	sigma factor activity
B1H20_RS32655	COG2045	Belongs to the ComB family
B1H20_RS32660	COG1834	amidinotransferase
B1H20_RS32670	COG1228	amidohydrolase
B1H20_RS32680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B1H20_RS32695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B1H20_RS32775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B1H20_RS32795	COG0463	Glycosyl transferase, family 2
B1H20_RS32865	COG0477	Major facilitator Superfamily
B1H20_RS32875	COG0254	rRNA binding
B1H20_RS32880	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B1H20_RS32885	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B1H20_RS32890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B1H20_RS32905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS32910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS32915	COG1120	ATPase activity
B1H20_RS32945	COG1132	(ABC) transporter
B1H20_RS32970	COG2304	oxidoreductase activity
B1H20_RS32990	COG0438	transferase activity, transferring glycosyl groups
B1H20_RS32995	COG0726	polysaccharide deacetylase
B1H20_RS33000	COG0728	peptidoglycan biosynthetic process
B1H20_RS33015	COG0438	transferase activity, transferring glycosyl groups
B1H20_RS33015	COG0297	glycogen (starch) synthase activity
B1H20_RS33030	COG1174	glycine betaine transport
B1H20_RS33035	COG1174	glycine betaine transport
B1H20_RS33050	COG0517	IMP dehydrogenase activity
B1H20_RS33050	COG1125	glycine betaine transport
B1H20_RS33080	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS33085	COG1960	acyl-CoA dehydrogenase activity
B1H20_RS33100	COG0601	transmembrane transport
B1H20_RS33105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1H20_RS33110	COG0444	Belongs to the ABC transporter superfamily
B1H20_RS33205	COG1796	DNA polymerase
B1H20_RS33205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B1H20_RS33265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B1H20_RS33290	COG1278	Cold shock
B1H20_RS33295	COG0477	Major facilitator Superfamily
B1H20_RS33310	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
B1H20_RS33315	COG0693	protein deglycase activity
B1H20_RS33330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS33335	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS33350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B1H20_RS33365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B1H20_RS33375	COG0596	Alpha beta hydrolase
B1H20_RS33385	COG1132	(ABC) transporter
B1H20_RS33390	COG4044	May play a role in the intracellular transport of hydrophobic ligands
B1H20_RS33410	COG1063	alcohol dehydrogenase
B1H20_RS33430	COG1349	DNA-binding transcription factor activity
B1H20_RS33470	COG1012	belongs to the aldehyde dehydrogenase family
B1H20_RS33525	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B1H20_RS33565	COG0640	Transcriptional regulator
B1H20_RS33580	COG2018	Roadblock/LC7 domain
B1H20_RS33590	COG0456	acetyltransferase
B1H20_RS33605	COG1024	Enoyl-CoA hydratase
B1H20_RS33620	COG1357	PFAM Pentapeptide repeats (8 copies)
B1H20_RS33630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B1H20_RS33640	COG2340	Cysteine-rich secretory protein family
B1H20_RS33680	COG0488	(ABC) transporter
B1H20_RS33700	COG0009	L-threonylcarbamoyladenylate synthase
B1H20_RS33725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B1H20_RS33740	COG2318	DinB family
B1H20_RS33750	COG1609	Transcriptional regulator
B1H20_RS33765	COG0395	ABC-type sugar transport system, permease component
B1H20_RS33770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1H20_RS33775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B1H20_RS33785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B1H20_RS33795	COG0714	Associated with various cellular activities
B1H20_RS33800	COG3552	Protein containing von Willebrand factor type A (VWA) domain
B1H20_RS33830	COG2205	protein histidine kinase activity
B1H20_RS33835	COG0745	RESPONSE REGULATOR receiver
B1H20_RS33850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1H20_RS33855	COG1120	ATPase activity
B1H20_RS33870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B1H20_RS33925	COG0586	Pfam SNARE associated Golgi protein
B1H20_RS33940	COG2226	methyltransferase
B1H20_RS33945	COG0745	RESPONSE REGULATOR receiver
B1H20_RS33950	COG2205	protein histidine kinase activity
B1H20_RS33960	COG1404	Belongs to the peptidase S8 family
B1H20_RS33985	COG1595	DNA-templated transcription, initiation
B1H20_RS33995	COG0831	urea catabolic process
B1H20_RS34000	COG0832	Belongs to the urease beta subunit family
B1H20_RS34010	COG0830	nickel cation binding
B1H20_RS34015	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B1H20_RS34020	COG0829	nickel cation binding
B1H20_RS34030	COG4214	carbohydrate transport
B1H20_RS34040	COG4213	ABC transporter substrate-binding protein
B1H20_RS34050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1H20_RS34055	COG0406	alpha-ribazole phosphatase activity
B1H20_RS34065	COG1070	Carbohydrate kinase
B1H20_RS34120	COG0395	ABC-type sugar transport system, permease component
B1H20_RS34145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1H20_RS34170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B1H20_RS34195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1H20_RS34215	COG0312	modulator of DNA gyrase
B1H20_RS34240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity