locus-tag	class	description
CP971_RS00045	COG0667	Aldo Keto reductase
CP971_RS00095	COG1733	regulation of RNA biosynthetic process
CP971_RS00100	COG0596	Alpha beta hydrolase
CP971_RS00130	COG2208	phosphoserine phosphatase activity
CP971_RS00130	COG2770	Histidine kinase
CP971_RS00160	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CP971_RS00170	COG0110	maltose O-acetyltransferase activity
CP971_RS00185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP971_RS00230	COG0318	PFAM AMP-dependent synthetase and ligase
CP971_RS00240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP971_RS00250	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP971_RS00265	COG2233	PERMEase
CP971_RS00295	COG2271	Major facilitator Superfamily
CP971_RS00315	COG1902	pentaerythritol trinitrate reductase activity
CP971_RS00385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP971_RS00480	COG3795	YCII-related domain
CP971_RS00485	COG4941	Belongs to the sigma-70 factor family
CP971_RS00495	COG2318	DinB family
CP971_RS00570	COG1595	DNA-templated transcription, initiation
CP971_RS00610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP971_RS00615	COG1309	transcriptional regulator
CP971_RS00625	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CP971_RS00650	COG2226	methyltransferase
CP971_RS00700	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP971_RS00710	COG0697	spore germination
CP971_RS00790	COG0842	Transport permease protein
CP971_RS00820	COG0640	Transcriptional regulator
CP971_RS00825	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS00825	COG3321	synthase
CP971_RS00825	COG0604	alcohol dehydrogenase
CP971_RS00850	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CP971_RS00885	COG0726	polysaccharide deacetylase
CP971_RS00900	COG0714	Associated with various cellular activities
CP971_RS00905	COG3864	Putative metallopeptidase domain
CP971_RS00925	COG1960	acyl-CoA dehydrogenase activity
CP971_RS00975	COG0477	Major facilitator Superfamily
CP971_RS00985	COG2197	response regulator
CP971_RS01005	COG1136	(ABC) transporter
CP971_RS01045	COG1940	carbohydrate kinase activity
CP971_RS01050	COG0626	cystathionine gamma-synthase activity
CP971_RS01070	COG0681	Belongs to the peptidase S26 family
CP971_RS01090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP971_RS01095	COG0488	(ABC) transporter
CP971_RS01145	COG1132	(ABC) transporter
CP971_RS01155	COG3794	PFAM blue (type 1) copper domain protein
CP971_RS01205	COG0517	IMP dehydrogenase activity
CP971_RS01220	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CP971_RS01230	COG1012	belongs to the aldehyde dehydrogenase family
CP971_RS01230	COG1454	alcohol dehydrogenase
CP971_RS01245	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CP971_RS01265	COG0549	Belongs to the carbamate kinase family
CP971_RS01270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP971_RS01275	COG2235	arginine
CP971_RS01280	COG0531	amino acid
CP971_RS01305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CP971_RS01325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP971_RS01335	COG2226	methyltransferase
CP971_RS01365	COG0137	argininosuccinate synthase activity
CP971_RS01380	COG1595	DNA-templated transcription, initiation
CP971_RS01385	COG1846	Transcriptional regulator
CP971_RS01390	COG1764	response to oxidative stress
CP971_RS01455	COG0463	Glycosyl transferase, family 2
CP971_RS01485	COG1937	Protein conserved in bacteria
CP971_RS01505	COG2197	response regulator
CP971_RS01510	COG4585	Histidine kinase
CP971_RS01515	COG2409	Drug exporters of the RND superfamily
CP971_RS01520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CP971_RS01525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP971_RS01540	COG0726	polysaccharide deacetylase
CP971_RS01545	COG0300	oxidoreductase activity
CP971_RS01575	COG0842	Transport permease protein
CP971_RS01575	COG1131	(ABC) transporter
CP971_RS01575	COG1716	ATPase activity
CP971_RS01615	COG1316	TRANSCRIPTIONal
CP971_RS01655	COG2124	cytochrome p450
CP971_RS01680	COG2226	methyltransferase
CP971_RS01685	COG1846	Transcriptional regulator
CP971_RS01690	COG0697	spore germination
CP971_RS01695	COG2910	NAD(P)H-binding
CP971_RS01725	COG1131	(ABC) transporter
CP971_RS01730	COG3559	Exporter of polyketide antibiotics
CP971_RS01765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP971_RS01780	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP971_RS01785	COG1129	ABC transporter
CP971_RS01805	COG2208	phosphoserine phosphatase activity
CP971_RS01810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP971_RS01835	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP971_RS01855	COG3285	dna ligase
CP971_RS01855	COG1793	dna ligase
CP971_RS01885	COG0346	lactoylglutathione lyase activity
CP971_RS01890	COG0477	Major facilitator Superfamily
CP971_RS01920	COG0387	Pfam Sodium calcium exchanger
CP971_RS01940	COG0363	glucosamine-6-phosphate deaminase activity
CP971_RS01945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP971_RS01960	COG1959	2 iron, 2 sulfur cluster binding
CP971_RS01970	COG0247	lactate metabolic process
CP971_RS01975	COG1139	Iron-sulfur cluster binding protein
CP971_RS01980	COG1556	Lactate utilization protein
CP971_RS01985	COG1834	amidinotransferase
CP971_RS02020	COG0477	Major facilitator Superfamily
CP971_RS02050	COG1846	Transcriptional regulator
CP971_RS02060	COG3511	phospholipase C
CP971_RS02075	COG3903	Transcriptional regulator
CP971_RS02075	COG3629	intracellular signal transduction
CP971_RS02080	COG3903	Transcriptional regulator
CP971_RS02080	COG3629	intracellular signal transduction
CP971_RS02125	COG0823	Involved in the tonB-independent uptake of proteins
CP971_RS02170	COG2132	Multicopper oxidase
CP971_RS02190	COG1191	sigma factor activity
CP971_RS02220	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP971_RS02230	COG0583	DNA-binding transcription factor activity
CP971_RS02240	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CP971_RS02255	COG0640	Transcriptional regulator
CP971_RS02270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP971_RS02310	COG3328	transposase activity
CP971_RS02335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP971_RS02360	COG0384	phenazine biosynthesis protein PhzF
CP971_RS02365	COG0640	Transcriptional regulator
CP971_RS02405	COG0017	Asparaginyl-tRNA synthetase
CP971_RS02410	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP971_RS02415	COG0318	PFAM AMP-dependent synthetase and ligase
CP971_RS02430	COG1960	acyl-CoA dehydrogenase activity
CP971_RS02495	COG1116	anion transmembrane transporter activity
CP971_RS02510	COG2197	response regulator
CP971_RS02515	COG4585	Histidine kinase
CP971_RS02520	COG1131	(ABC) transporter
CP971_RS02535	COG0477	Major facilitator Superfamily
CP971_RS02545	COG3629	intracellular signal transduction
CP971_RS02545	COG3903	Transcriptional regulator
CP971_RS02550	COG0667	Aldo Keto reductase
CP971_RS02575	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP971_RS02615	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS02620	COG1652	LysM domain
CP971_RS02625	COG2197	response regulator
CP971_RS02655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP971_RS02660	COG0589	response to stress
CP971_RS02710	COG2205	protein histidine kinase activity
CP971_RS02715	COG0745	RESPONSE REGULATOR receiver
CP971_RS02735	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CP971_RS02755	COG3511	phospholipase C
CP971_RS02810	COG2957	Belongs to the agmatine deiminase family
CP971_RS02815	COG2957	Belongs to the agmatine deiminase family
CP971_RS02880	COG0464	growth
CP971_RS02895	COG2197	response regulator
CP971_RS02935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP971_RS02950	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CP971_RS02955	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CP971_RS02965	COG2723	6-phospho-beta-galactosidase activity
CP971_RS02995	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CP971_RS03000	COG0191	fructose-bisphosphate aldolase activity
CP971_RS03005	COG1105	Belongs to the carbohydrate kinase PfkB family
CP971_RS03030	COG0395	ABC-type sugar transport system, permease component
CP971_RS03045	COG3833	ABC-type maltose transport systems, permease component
CP971_RS03050	COG1175	transmembrane transport
CP971_RS03085	COG1834	amidinotransferase
CP971_RS03095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP971_RS03100	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP971_RS03110	COG0504	CTP synthase activity
CP971_RS03115	COG0475	glutathione-regulated potassium exporter activity
CP971_RS03120	COG0717	Belongs to the dCTP deaminase family
CP971_RS03180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP971_RS03185	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CP971_RS03195	COG1215	transferase activity, transferring glycosyl groups
CP971_RS03205	COG4310	Domain of unknown function (DUF2172)
CP971_RS03210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP971_RS03220	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP971_RS03255	COG0367	asparagine synthase
CP971_RS03275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP971_RS03290	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS03300	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP971_RS03330	COG0586	Pfam SNARE associated Golgi protein
CP971_RS03335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP971_RS03340	COG2130	NADP-dependent
CP971_RS03345	COG0789	Transcriptional regulator
CP971_RS03375	COG1289	transmembrane transporter activity
CP971_RS03380	COG0154	amidase activity
CP971_RS03385	COG2124	cytochrome p450
CP971_RS03425	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS03430	COG1720	tRNA m6t6A37 methyltransferase activity
CP971_RS03445	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP971_RS03450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP971_RS03460	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP971_RS03465	COG0596	Alpha beta hydrolase
CP971_RS03470	COG0494	nUDIX hydrolase
CP971_RS03495	COG2801	Transposase and inactivated derivatives
CP971_RS03510	COG3328	transposase activity
CP971_RS03575	COG0583	DNA-binding transcription factor activity
CP971_RS03590	COG2318	DinB family
CP971_RS03605	COG2066	Belongs to the glutaminase family
CP971_RS03610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP971_RS03620	COG0367	asparagine synthase
CP971_RS03635	COG0076	glutamate decarboxylase activity
CP971_RS03665	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CP971_RS03670	COG3442	glutamine amidotransferase
CP971_RS03675	COG0205	6-phosphofructokinase activity
CP971_RS03695	COG3903	Transcriptional regulator
CP971_RS03695	COG3629	intracellular signal transduction
CP971_RS03700	COG2318	DinB family
CP971_RS03705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP971_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS03715	COG0477	Major facilitator Superfamily
CP971_RS03725	COG4941	Belongs to the sigma-70 factor family
CP971_RS03745	COG2838	Isocitrate dehydrogenase
CP971_RS03765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP971_RS03770	COG0531	amino acid
CP971_RS03780	COG2329	Antibiotic biosynthesis monooxygenase
CP971_RS03795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP971_RS03800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP971_RS03835	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CP971_RS03845	COG0531	amino acid
CP971_RS03865	COG0583	DNA-binding transcription factor activity
CP971_RS03890	COG4608	Belongs to the ABC transporter superfamily
CP971_RS03905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP971_RS03910	COG0747	negative chemotaxis
CP971_RS03940	COG0438	transferase activity, transferring glycosyl groups
CP971_RS03945	COG0438	transferase activity, transferring glycosyl groups
CP971_RS03985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP971_RS04015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP971_RS04025	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP971_RS04030	COG3473	Maleate cis-trans isomerase
CP971_RS04095	COG4290	ribonuclease
CP971_RS04110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP971_RS04120	COG1846	Transcriptional regulator
CP971_RS04125	COG0596	Alpha beta hydrolase
CP971_RS04165	COG1796	DNA polymerase
CP971_RS04165	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CP971_RS04175	COG2313	pseudouridylate synthase activity
CP971_RS04180	COG0583	DNA-binding transcription factor activity
CP971_RS04190	COG2197	response regulator
CP971_RS04195	COG4585	Histidine kinase
CP971_RS04215	COG0366	Alpha amylase catalytic
CP971_RS04225	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP971_RS04240	COG1414	Transcriptional regulator
CP971_RS04255	COG0741	lytic transglycosylase activity
CP971_RS04255	COG1196	nuclear chromosome segregation
CP971_RS04255	COG0739	heme binding
CP971_RS04260	COG0477	Major facilitator Superfamily
CP971_RS04265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP971_RS04310	COG0477	Major facilitator Superfamily
CP971_RS04315	COG0412	Dienelactone hydrolase
CP971_RS04350	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP971_RS04350	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP971_RS04360	COG0477	Major facilitator Superfamily
CP971_RS04365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP971_RS04370	COG2949	membrane
CP971_RS04410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP971_RS04445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP971_RS04450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP971_RS04465	COG2040	homocysteine
CP971_RS04470	COG1414	Transcriptional regulator
CP971_RS04475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP971_RS04480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP971_RS04485	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP971_RS04490	COG0402	S-adenosylhomocysteine deaminase activity
CP971_RS04495	COG1309	transcriptional regulator
CP971_RS04505	COG3265	gluconokinase activity
CP971_RS04510	COG1802	Transcriptional regulator
CP971_RS04525	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP971_RS04555	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CP971_RS04565	COG1695	Transcriptional regulator
CP971_RS04570	COG2226	methyltransferase
CP971_RS04595	COG1960	acyl-CoA dehydrogenase activity
CP971_RS04630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CP971_RS04635	COG0463	Glycosyl transferase, family 2
CP971_RS04650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP971_RS04655	COG0438	transferase activity, transferring glycosyl groups
CP971_RS04690	COG1940	carbohydrate kinase activity
CP971_RS04715	COG3835	regulator
CP971_RS04725	COG0110	maltose O-acetyltransferase activity
CP971_RS04765	COG0445	tRNA wobble uridine modification
CP971_RS04790	COG0791	NLP P60 protein
CP971_RS04790	COG3883	PFAM NLP P60 protein
CP971_RS04795	COG0318	PFAM AMP-dependent synthetase and ligase
CP971_RS04800	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP971_RS04850	COG4221	oxidoreductase activity
CP971_RS04860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP971_RS04865	COG0765	amino acid transport
CP971_RS04895	COG1309	transcriptional regulator
CP971_RS04930	COG0366	Alpha amylase catalytic
CP971_RS04935	COG3833	ABC-type maltose transport systems, permease component
CP971_RS04945	COG2182	Extracellular solute-binding protein
CP971_RS04965	COG2124	cytochrome p450
CP971_RS04970	COG1012	belongs to the aldehyde dehydrogenase family
CP971_RS04980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP971_RS04985	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP971_RS05010	COG2855	membrane
CP971_RS05020	COG0583	DNA-binding transcription factor activity
CP971_RS05025	COG0765	amino acid transport
CP971_RS05030	COG0765	amino acid transport
CP971_RS05040	COG1126	abc transporter atp-binding protein
CP971_RS05050	COG1132	(ABC) transporter
CP971_RS05060	COG0656	L-ascorbic acid biosynthetic process
CP971_RS05075	COG0671	phosphoesterase, PA-phosphatase related
CP971_RS05110	COG1657	PFAM Prenyltransferase squalene oxidase
CP971_RS05120	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP971_RS05130	COG1562	ergosterol biosynthetic process
CP971_RS05140	COG1134	teichoic acid transport
CP971_RS05160	COG0371	Dehydrogenase
CP971_RS05165	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CP971_RS05170	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP971_RS05185	COG0531	amino acid
CP971_RS05205	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP971_RS05220	COG0697	spore germination
CP971_RS05245	COG2318	DinB family
CP971_RS05255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP971_RS05290	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CP971_RS05305	COG3708	Transcriptional regulator
CP971_RS05305	COG2207	Transcriptional regulator
CP971_RS05310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP971_RS05315	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP971_RS05325	COG5001	Diguanylate cyclase
CP971_RS05345	COG3572	ergothioneine biosynthetic process
CP971_RS05350	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP971_RS05355	COG0121	glutamine amidotransferase
CP971_RS05360	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CP971_RS05365	COG0477	Major facilitator Superfamily
CP971_RS05370	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CP971_RS05380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP971_RS05385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP971_RS05390	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CP971_RS05400	COG1088	dTDP-glucose 4,6-dehydratase activity
CP971_RS05470	COG3547	Transposase (IS116 IS110 IS902 family)
CP971_RS05585	COG1960	acyl-CoA dehydrogenase activity
CP971_RS05590	COG0183	Belongs to the thiolase family
CP971_RS05655	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CP971_RS05700	COG1946	Acyl-CoA thioesterase
CP971_RS05705	COG1309	transcriptional regulator
CP971_RS05710	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP971_RS05745	COG0708	Exodeoxyribonuclease III
CP971_RS05750	COG0405	Gamma-glutamyltransferase
CP971_RS05760	COG1940	carbohydrate kinase activity
CP971_RS05785	COG3835	regulator
CP971_RS05805	COG2252	PERMEase
CP971_RS05815	COG1280	lysine exporter protein (LysE YggA)
CP971_RS05845	COG0753	catalase activity
CP971_RS05850	COG4266	Belongs to the allantoicase family
CP971_RS05855	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP971_RS05860	COG1929	Belongs to the glycerate kinase type-1 family
CP971_RS05865	COG2084	Dehydrogenase
CP971_RS05870	COG3622	Belongs to the hyi family
CP971_RS05890	COG2351	hydroxyisourate hydrolase activity
CP971_RS05900	COG2233	PERMEase
CP971_RS05915	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CP971_RS05920	COG1414	Transcriptional regulator
CP971_RS05945	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS05970	COG0667	Aldo Keto reductase
CP971_RS05975	COG0745	RESPONSE REGULATOR receiver
CP971_RS05990	COG2018	Roadblock/LC7 domain
CP971_RS05995	COG0642	Histidine kinase
CP971_RS06015	COG0748	coenzyme F420 binding
CP971_RS06020	COG2755	lipolytic protein G-D-S-L family
CP971_RS06025	COG2755	lipolytic protein G-D-S-L family
CP971_RS06040	COG0420	3'-5' exonuclease activity
CP971_RS06045	COG0419	ATPase involved in DNA repair
CP971_RS06080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP971_RS06095	COG1132	(ABC) transporter
CP971_RS06100	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS06145	COG2072	flavoprotein involved in K transport
CP971_RS06155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP971_RS06165	COG1733	regulation of RNA biosynthetic process
CP971_RS06180	COG0515	serine threonine protein kinase
CP971_RS06205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP971_RS06210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP971_RS06215	COG1120	ATPase activity
CP971_RS06220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP971_RS06235	COG2814	Major facilitator Superfamily
CP971_RS06240	COG4264	IucA IucC family
CP971_RS06250	COG0483	inositol monophosphate 1-phosphatase activity
CP971_RS06265	COG4565	transcriptional regulatory protein
CP971_RS06270	COG3290	protein histidine kinase activity
CP971_RS06275	COG1301	dicarboxylic acid transport
CP971_RS06305	COG2018	Roadblock/LC7 domain
CP971_RS06315	COG5001	Diguanylate cyclase
CP971_RS06315	COG3300	MHYT domain
CP971_RS06320	COG2124	cytochrome p450
CP971_RS06330	COG0725	ABC transporter, periplasmic molybdate-binding protein
CP971_RS06345	COG2197	response regulator
CP971_RS06350	COG4585	Histidine kinase
CP971_RS06355	COG1131	(ABC) transporter
CP971_RS06385	COG0393	Putative heavy-metal-binding
CP971_RS06390	COG2072	flavoprotein involved in K transport
CP971_RS06395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP971_RS06400	COG2151	metal-sulfur cluster biosynthetic enzyme
CP971_RS06405	COG3396	Phenylacetate-CoA oxygenase
CP971_RS06410	COG3460	Phenylacetate-CoA oxygenase
CP971_RS06415	COG3396	Phenylacetate-CoA oxygenase
CP971_RS06425	COG2197	response regulator
CP971_RS06440	COG0667	Aldo Keto reductase
CP971_RS06445	COG1309	transcriptional regulator
CP971_RS06460	COG1953	Uracil, thiamine, allantoin
CP971_RS06470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP971_RS06500	COG0517	IMP dehydrogenase activity
CP971_RS06500	COG1125	glycine betaine transport
CP971_RS06505	COG1174	glycine betaine transport
CP971_RS06510	COG1174	glycine betaine transport
CP971_RS06530	COG3979	chitinase
CP971_RS06535	COG2814	Major facilitator Superfamily
CP971_RS06560	COG1960	acyl-CoA dehydrogenase activity
CP971_RS06585	COG1396	sequence-specific DNA binding
CP971_RS06600	COG0114	fumarate hydratase activity
CP971_RS06625	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CP971_RS06645	COG1024	Enoyl-CoA hydratase
CP971_RS06705	COG0477	Major facilitator Superfamily
CP971_RS06725	COG1120	ATPase activity
CP971_RS06790	COG1846	Transcriptional regulator
CP971_RS06800	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP971_RS06805	COG0714	Associated with various cellular activities
CP971_RS06845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP971_RS06850	COG2843	Capsule synthesis protein
CP971_RS06860	COG0501	Belongs to the peptidase M48B family
CP971_RS06900	COG2197	response regulator
CP971_RS06925	COG0829	nickel cation binding
CP971_RS06930	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP971_RS06935	COG0830	nickel cation binding
CP971_RS06940	COG0804	urea catabolic process
CP971_RS06955	COG0831	urea catabolic process
CP971_RS06970	COG2267	carboxylic ester hydrolase activity
CP971_RS07000	COG0583	DNA-binding transcription factor activity
CP971_RS07010	COG0667	Aldo Keto reductase
CP971_RS07080	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP971_RS07095	COG3409	Peptidoglycan-binding domain 1 protein
CP971_RS07105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP971_RS07110	COG2186	Transcriptional regulator
CP971_RS07135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP971_RS07225	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP971_RS07225	COG1902	pentaerythritol trinitrate reductase activity
CP971_RS07260	COG0277	FAD linked oxidase domain protein
CP971_RS07320	COG3469	chitinase activity
CP971_RS07350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP971_RS07355	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CP971_RS07370	COG3629	intracellular signal transduction
CP971_RS07370	COG3903	Transcriptional regulator
CP971_RS07380	COG2197	response regulator
CP971_RS07385	COG4585	Histidine kinase
CP971_RS07430	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP971_RS07435	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP971_RS07440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP971_RS07445	COG0254	rRNA binding
CP971_RS07455	COG0667	Aldo Keto reductase
CP971_RS07480	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CP971_RS07485	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CP971_RS07490	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CP971_RS07500	COG0531	amino acid
CP971_RS07560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP971_RS07565	COG0667	Aldo Keto reductase
CP971_RS07625	COG1609	Transcriptional regulator
CP971_RS07670	COG0443	Heat shock 70 kDa protein
CP971_RS07685	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP971_RS07715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP971_RS07720	COG1121	(ABC) transporter
CP971_RS07755	COG0523	cobalamin synthesis protein
CP971_RS07760	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP971_RS07770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP971_RS07775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP971_RS07780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP971_RS07785	COG0254	rRNA binding
CP971_RS07800	COG0701	Predicted permease
CP971_RS07845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP971_RS07850	COG1120	ATPase activity
CP971_RS07860	COG2124	cytochrome p450
CP971_RS07865	COG0367	asparagine synthase
CP971_RS07870	COG2814	Major facilitator Superfamily
CP971_RS07900	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CP971_RS07905	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CP971_RS07910	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CP971_RS07975	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CP971_RS08035	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS08070	COG0477	Major facilitator Superfamily
CP971_RS08075	COG1012	belongs to the aldehyde dehydrogenase family
CP971_RS08080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CP971_RS08085	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP971_RS08090	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP971_RS08105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP971_RS08115	COG0475	glutathione-regulated potassium exporter activity
CP971_RS08130	COG1309	transcriptional regulator
CP971_RS08135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CP971_RS08140	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CP971_RS08145	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP971_RS08160	COG1064	alcohol dehydrogenase
CP971_RS08210	COG0515	serine threonine protein kinase
CP971_RS08225	COG4974	Belongs to the 'phage' integrase family
CP971_RS08240	COG1116	anion transmembrane transporter activity
CP971_RS08275	COG1215	transferase activity, transferring glycosyl groups
CP971_RS08295	COG1960	acyl-CoA dehydrogenase activity
CP971_RS08300	COG0318	PFAM AMP-dependent synthetase and ligase
CP971_RS08315	COG0577	efflux transmembrane transporter activity
CP971_RS08315	COG1136	(ABC) transporter
CP971_RS08320	COG4585	Histidine kinase
CP971_RS08325	COG2197	response regulator
CP971_RS08330	COG3629	intracellular signal transduction
CP971_RS08330	COG3903	Transcriptional regulator
CP971_RS08350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP971_RS08380	COG2801	Transposase and inactivated derivatives
CP971_RS08405	COG0477	Major facilitator Superfamily
CP971_RS08415	COG1946	Acyl-CoA thioesterase
CP971_RS08430	COG1652	LysM domain
CP971_RS08445	COG1160	GTP binding
CP971_RS08450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CP971_RS08485	COG1187	pseudouridine synthase activity
CP971_RS08490	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CP971_RS08495	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CP971_RS08510	COG0686	Belongs to the AlaDH PNT family
CP971_RS08515	COG3903	Transcriptional regulator
CP971_RS08515	COG3629	intracellular signal transduction
CP971_RS08520	COG0494	nUDIX hydrolase
CP971_RS08525	COG0504	CTP synthase activity
CP971_RS08530	COG3387	PFAM Glycoside hydrolase 15-related
CP971_RS08540	COG0497	DNA recombination
CP971_RS08550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP971_RS08555	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP971_RS08580	COG0647	UMP catabolic process
CP971_RS08625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CP971_RS08640	COG2154	pterin-4-alpha-carbinolamine dehydratase
CP971_RS08665	COG1119	ATPase activity
CP971_RS08675	COG2197	response regulator
CP971_RS08680	COG4585	Histidine kinase
CP971_RS08685	COG0842	Transport permease protein
CP971_RS08685	COG1131	(ABC) transporter
CP971_RS08685	COG1716	ATPase activity
CP971_RS08690	COG0560	Phosphoserine phosphatase
CP971_RS08690	COG3830	Belongs to the UPF0237 family
CP971_RS08700	COG2807	transmembrane transport
CP971_RS08705	COG2186	Transcriptional regulator
CP971_RS08710	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CP971_RS08735	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CP971_RS08750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP971_RS08755	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP971_RS08765	COG1063	alcohol dehydrogenase
CP971_RS08770	COG2176	DNA-directed DNA polymerase activity
CP971_RS08785	COG0789	Transcriptional regulator
CP971_RS08830	COG0488	(ABC) transporter
CP971_RS08865	COG0728	peptidoglycan biosynthetic process
CP971_RS08875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP971_RS08905	COG0174	glutamine synthetase
CP971_RS08925	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP971_RS08925	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP971_RS08930	COG2301	Belongs to the HpcH HpaI aldolase family
CP971_RS08940	COG1960	acyl-CoA dehydrogenase activity
CP971_RS08945	COG0688	phosphatidylethanolamine metabolic process
CP971_RS08970	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CP971_RS08975	COG1492	cobalamin metabolic process
CP971_RS08990	COG1797	cobyrinic acid a,c-diamide synthase activity
CP971_RS08995	COG3896	Chloramphenicol phosphotransferase-like protein
CP971_RS09015	COG2226	methyltransferase
CP971_RS09025	COG0697	spore germination
CP971_RS09045	COG3511	phospholipase C
CP971_RS09085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP971_RS09100	COG0531	amino acid
CP971_RS09110	COG2175	clavaminate synthase activity
CP971_RS09115	COG2188	Transcriptional regulator
CP971_RS09125	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP971_RS09135	COG3842	ATPase activity
CP971_RS09140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP971_RS09200	COG0586	Pfam SNARE associated Golgi protein
CP971_RS09245	COG0473	3-isopropylmalate dehydrogenase activity
CP971_RS09245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CP971_RS09260	COG1012	belongs to the aldehyde dehydrogenase family
CP971_RS09265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP971_RS09305	COG0822	iron-sulfur transferase activity
CP971_RS09310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP971_RS09315	COG0396	ATPase activity
CP971_RS09355	COG1612	heme a metabolic process
CP971_RS09365	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CP971_RS09395	COG0109	protoheme IX farnesyltransferase activity
CP971_RS09400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CP971_RS09405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP971_RS09420	COG0363	glucosamine-6-phosphate deaminase activity
CP971_RS09430	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP971_RS09435	COG0149	triose-phosphate isomerase activity
CP971_RS09440	COG0126	phosphoglycerate kinase activity
CP971_RS09445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP971_RS09450	COG1481	regulation of sporulation
CP971_RS09460	COG1660	Displays ATPase and GTPase activities
CP971_RS09465	COG0322	excinuclease ABC activity
CP971_RS09485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP971_RS09500	COG0556	nucleotide-excision repair
CP971_RS09520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CP971_RS09525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP971_RS09585	COG3253	May function as heme-dependent peroxidase
CP971_RS09590	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP971_RS09600	COG1683	Conserved Protein
CP971_RS09610	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CP971_RS09630	COG0183	Belongs to the thiolase family
CP971_RS09635	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP971_RS09635	COG1024	Enoyl-CoA hydratase
CP971_RS09650	COG1940	carbohydrate kinase activity
CP971_RS09690	COG0668	transmembrane transport
CP971_RS09705	COG1175	transmembrane transport
CP971_RS09710	COG0395	ABC-type sugar transport system, permease component
CP971_RS09715	COG1486	melibiose metabolic process
CP971_RS09740	COG4585	Histidine kinase
CP971_RS09745	COG1131	(ABC) transporter
CP971_RS09760	COG2188	Transcriptional regulator
CP971_RS09780	COG2255	four-way junction helicase activity
CP971_RS09785	COG1136	(ABC) transporter
CP971_RS09785	COG0577	efflux transmembrane transporter activity
CP971_RS09820	COG0154	amidase activity
CP971_RS09835	COG1834	amidinotransferase
CP971_RS09865	COG1136	(ABC) transporter
CP971_RS09865	COG0577	efflux transmembrane transporter activity
CP971_RS09875	COG2197	response regulator
CP971_RS09890	COG0473	3-isopropylmalate dehydrogenase activity
CP971_RS09900	COG0066	3-isopropylmalate dehydratase activity
CP971_RS09905	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP971_RS09930	COG0583	DNA-binding transcription factor activity
CP971_RS09935	COG1278	Cold shock
CP971_RS09940	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP971_RS09940	COG0515	serine threonine protein kinase
CP971_RS09950	COG0583	DNA-binding transcription factor activity
CP971_RS09960	COG0318	PFAM AMP-dependent synthetase and ligase
CP971_RS09980	COG1012	belongs to the aldehyde dehydrogenase family
CP971_RS09990	COG4977	sequence-specific DNA binding
CP971_RS09995	COG1335	isochorismatase
CP971_RS10005	COG1595	DNA-templated transcription, initiation
CP971_RS10010	COG2318	DinB family
CP971_RS10025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP971_RS10110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP971_RS10115	COG0477	Major facilitator Superfamily
CP971_RS10125	COG1024	Enoyl-CoA hydratase
CP971_RS10135	COG1960	acyl-CoA dehydrogenase activity
CP971_RS10150	COG0339	signal peptide processing
CP971_RS10155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP971_RS10155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP971_RS10165	COG2376	Dihydroxyacetone kinase
CP971_RS10170	COG1461	Dihydroxyacetone kinase
CP971_RS10190	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS10200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP971_RS10240	COG0756	dUTP diphosphatase activity
CP971_RS10265	COG2205	protein histidine kinase activity
CP971_RS10270	COG0745	RESPONSE REGULATOR receiver
CP971_RS10285	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CP971_RS10320	COG1435	thymidine kinase activity
CP971_RS10340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP971_RS10345	COG1690	Belongs to the RtcB family
CP971_RS10355	COG0612	Peptidase, M16
CP971_RS10360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP971_RS10380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP971_RS10390	COG3290	protein histidine kinase activity
CP971_RS10395	COG4565	transcriptional regulatory protein
CP971_RS10400	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP971_RS10410	COG2197	response regulator
CP971_RS10415	COG4585	Histidine kinase
CP971_RS10425	COG0187	DNA topoisomerase II activity
CP971_RS10440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP971_RS10445	COG2186	Transcriptional regulator
CP971_RS10490	COG0514	ATP-dependent DNA helicase (RecQ)
CP971_RS10505	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CP971_RS10525	COG0395	ABC-type sugar transport system, permease component
CP971_RS10530	COG1175	transmembrane transport
CP971_RS10535	COG1653	transport
CP971_RS10570	COG0542	response to heat
CP971_RS10580	COG0702	epimerase
CP971_RS10585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP971_RS10590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CP971_RS10595	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP971_RS10635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP971_RS10640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP971_RS10645	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CP971_RS10655	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CP971_RS10670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP971_RS10675	COG2358	TRAP transporter, solute receptor (TAXI family
CP971_RS10680	COG2205	protein histidine kinase activity
CP971_RS10685	COG0745	RESPONSE REGULATOR receiver
CP971_RS10690	COG1126	abc transporter atp-binding protein
CP971_RS10700	COG0765	amino acid transport
CP971_RS10705	COG0765	amino acid transport
CP971_RS10710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP971_RS10735	COG1404	Belongs to the peptidase S8 family
CP971_RS10740	COG1201	RNA secondary structure unwinding
CP971_RS10750	COG1396	sequence-specific DNA binding
CP971_RS10755	COG1546	Belongs to the CinA family
CP971_RS10755	COG1058	Belongs to the CinA family
CP971_RS10765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP971_RS10775	COG1674	ftsk spoiiie
CP971_RS10785	COG0784	Response regulator, receiver
CP971_RS10785	COG2205	protein histidine kinase activity
CP971_RS10840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP971_RS10845	COG1177	transmembrane transport
CP971_RS10850	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP971_RS10855	COG3842	ATPase activity
CP971_RS10860	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CP971_RS10880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP971_RS10885	COG1012	belongs to the aldehyde dehydrogenase family
CP971_RS10895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP971_RS10900	COG1136	(ABC) transporter
CP971_RS10910	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CP971_RS10915	COG0575	Belongs to the CDS family
CP971_RS10925	COG0233	cytoplasmic translational termination
CP971_RS10930	COG0528	UMP kinase activity
CP971_RS10935	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CP971_RS10940	COG0052	Belongs to the universal ribosomal protein uS2 family
CP971_RS10955	COG1191	sigma factor activity
CP971_RS10970	COG0792	nuclease activity
CP971_RS10980	COG0494	nUDIX hydrolase
CP971_RS10990	COG0681	Belongs to the peptidase S26 family
CP971_RS10995	COG0681	Belongs to the peptidase S26 family
CP971_RS11005	COG0335	large ribosomal subunit rRNA binding
CP971_RS11010	COG0336	Belongs to the RNA methyltransferase TrmD family
CP971_RS11015	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CP971_RS11020	COG1837	Belongs to the UPF0109 family
CP971_RS11025	COG0228	four-way junction DNA binding
CP971_RS11035	COG0442	prolyl-tRNA aminoacylation
CP971_RS11045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CP971_RS11060	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CP971_RS11100	COG1254	Belongs to the acylphosphatase family
CP971_RS11115	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP971_RS11120	COG0571	ribonuclease III activity
CP971_RS11125	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CP971_RS11140	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CP971_RS11145	COG0742	ribosomal rna small subunit methyltransferase
CP971_RS11160	COG1461	Dihydroxyacetone kinase
CP971_RS11165	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP971_RS11170	COG0351	phosphomethylpyrimidine kinase
CP971_RS11175	COG0205	6-phosphofructokinase activity
CP971_RS11195	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP971_RS11200	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP971_RS11215	COG0776	regulation of translation
CP971_RS11225	COG0066	3-isopropylmalate dehydratase activity
CP971_RS11230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP971_RS11235	COG1414	Transcriptional regulator
CP971_RS11265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CP971_RS11270	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP971_RS11285	COG2018	Roadblock/LC7 domain
CP971_RS11305	COG2018	Roadblock/LC7 domain
CP971_RS11320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP971_RS11325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP971_RS11330	COG0473	3-isopropylmalate dehydrogenase activity
CP971_RS11345	COG1404	Belongs to the peptidase S8 family
CP971_RS11355	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CP971_RS11360	COG0440	acetolactate synthase activity
CP971_RS11370	COG5001	Diguanylate cyclase
CP971_RS11375	COG1672	PFAM Archaeal ATPase
CP971_RS11375	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP971_RS11380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP971_RS11390	COG0154	amidase activity
CP971_RS11395	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP971_RS11405	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP971_RS11420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP971_RS11460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP971_RS11465	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS11490	COG0482	sulfurtransferase activity
CP971_RS11505	COG2860	membrane
CP971_RS11510	COG4608	Belongs to the ABC transporter superfamily
CP971_RS11520	COG0601	transmembrane transport
CP971_RS11530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP971_RS11545	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP971_RS11550	COG0509	glycine decarboxylation via glycine cleavage system
CP971_RS11555	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP971_RS11560	COG1760	l-serine dehydratase
CP971_RS11565	COG0477	Major facilitator Superfamily
CP971_RS11595	COG0697	spore germination
CP971_RS11645	COG1376	ErfK ybiS ycfS ynhG family protein
CP971_RS11660	COG1132	(ABC) transporter
CP971_RS11665	COG1132	(ABC) transporter
CP971_RS11670	COG0058	SHG alpha-glucan phosphorylase activity
CP971_RS11675	COG0366	Alpha amylase catalytic
CP971_RS11680	COG0366	Alpha amylase catalytic
CP971_RS11690	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CP971_RS11695	COG0280	phosphate acetyltransferase
CP971_RS11695	COG0857	belongs to the CobB CobQ family
CP971_RS11700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CP971_RS11735	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP971_RS11735	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP971_RS11745	COG1846	Transcriptional regulator
CP971_RS11790	COG0183	Belongs to the thiolase family
CP971_RS11795	COG0346	lactoylglutathione lyase activity
CP971_RS11815	COG2267	carboxylic ester hydrolase activity
CP971_RS11845	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CP971_RS11860	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP971_RS11865	COG2197	response regulator
CP971_RS11870	COG4585	Histidine kinase
CP971_RS11890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CP971_RS11895	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CP971_RS11900	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CP971_RS11905	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CP971_RS11910	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP971_RS11915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP971_RS11920	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP971_RS11940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP971_RS11945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP971_RS11955	COG2890	protein-(glutamine-N5) methyltransferase activity
CP971_RS11960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CP971_RS11965	COG0254	rRNA binding
CP971_RS11970	COG1316	TRANSCRIPTIONal
CP971_RS11980	COG0083	homoserine kinase activity
CP971_RS11985	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP971_RS11990	COG0460	homoserine dehydrogenase
CP971_RS11995	COG0019	diaminopimelate decarboxylase activity
CP971_RS12000	COG0018	arginyl-trna synthetase
CP971_RS12005	COG0745	RESPONSE REGULATOR receiver
CP971_RS12020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP971_RS12035	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP971_RS12040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP971_RS12045	COG0515	serine threonine protein kinase
CP971_RS12045	COG2815	serine threonine protein kinase
CP971_RS12050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP971_RS12055	COG1126	abc transporter atp-binding protein
CP971_RS12080	COG0765	amino acid transport
CP971_RS12090	COG0515	serine threonine protein kinase
CP971_RS12090	COG2815	serine threonine protein kinase
CP971_RS12115	COG0477	Major facilitator Superfamily
CP971_RS12140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CP971_RS12150	COG0745	RESPONSE REGULATOR receiver
CP971_RS12155	COG2205	protein histidine kinase activity
CP971_RS12160	COG0567	Dehydrogenase, E1 component
CP971_RS12160	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP971_RS12185	COG0604	alcohol dehydrogenase
CP971_RS12190	COG0281	malic enzyme
CP971_RS12195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP971_RS12205	COG0765	amino acid transport
CP971_RS12230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP971_RS12235	COG1120	ATPase activity
CP971_RS12255	COG2172	sigma factor antagonist activity
CP971_RS12270	COG1597	lipid kinase activity
CP971_RS12285	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP971_RS12295	COG1472	Belongs to the glycosyl hydrolase 3 family
CP971_RS12300	COG0395	ABC-type sugar transport system, permease component
CP971_RS12305	COG1175	transmembrane transport
CP971_RS12310	COG2182	Extracellular solute-binding protein
CP971_RS12315	COG2188	Transcriptional regulator
CP971_RS12365	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CP971_RS12365	COG4124	Belongs to the glycosyl hydrolase 26 family
CP971_RS12380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP971_RS12415	COG0242	peptide deformylase activity
CP971_RS12430	COG2199	diguanylate cyclase activity
CP971_RS12430	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CP971_RS12440	COG1595	DNA-templated transcription, initiation
CP971_RS12450	COG2135	peptidase activity
CP971_RS12460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP971_RS12465	COG1162	GTPase activity
CP971_RS12475	COG0483	inositol monophosphate 1-phosphatase activity
CP971_RS12480	COG0753	catalase activity
CP971_RS12505	COG1615	UPF0182 protein
CP971_RS12515	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP971_RS12560	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP971_RS12590	COG2188	Transcriptional regulator
CP971_RS12615	COG4591	ABC-type transport system involved in lipoprotein release permease component
CP971_RS12615	COG1136	(ABC) transporter
CP971_RS12640	COG0210	DNA helicase
CP971_RS12675	COG0596	Alpha beta hydrolase
CP971_RS12705	COG0513	Belongs to the DEAD box helicase family
CP971_RS12710	COG0596	Alpha beta hydrolase
CP971_RS12720	COG0613	PHP domain protein
CP971_RS12730	COG0598	Magnesium transport protein CorA
CP971_RS12745	COG2239	Acts as a magnesium transporter
CP971_RS12765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP971_RS12775	COG1595	DNA-templated transcription, initiation
CP971_RS12790	COG1024	Enoyl-CoA hydratase
CP971_RS12795	COG0519	Catalyzes the synthesis of GMP from XMP
CP971_RS12805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CP971_RS12810	COG1611	Belongs to the LOG family
CP971_RS12815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP971_RS12850	COG2197	response regulator
CP971_RS12860	COG4585	Histidine kinase
CP971_RS12870	COG1131	(ABC) transporter
CP971_RS12885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP971_RS12905	COG0444	Belongs to the ABC transporter superfamily
CP971_RS12910	COG4608	Belongs to the ABC transporter superfamily
CP971_RS12920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP971_RS12935	COG4608	Belongs to the ABC transporter superfamily
CP971_RS12940	COG0444	Belongs to the ABC transporter superfamily
CP971_RS12945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP971_RS12950	COG0601	transmembrane transport
CP971_RS12960	COG1217	gtp-binding protein TYPA
CP971_RS12995	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP971_RS12995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP971_RS13005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP971_RS13010	COG0012	GTP binding
CP971_RS13030	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CP971_RS13040	COG1570	exodeoxyribonuclease VII activity
CP971_RS13050	COG1722	exodeoxyribonuclease VII activity
CP971_RS13055	COG0778	Nitroreductase
CP971_RS13085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CP971_RS13085	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CP971_RS13090	COG2188	Transcriptional regulator
CP971_RS13105	COG3629	intracellular signal transduction
CP971_RS13105	COG3903	Transcriptional regulator
CP971_RS13120	COG2409	Drug exporters of the RND superfamily
CP971_RS13135	COG0450	alkyl hydroperoxide reductase
CP971_RS13140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP971_RS13165	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CP971_RS13170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP971_RS13185	COG0436	Aminotransferase
CP971_RS13190	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CP971_RS13205	COG0477	Major facilitator Superfamily
CP971_RS13210	COG1309	transcriptional regulator
CP971_RS13250	COG1331	Highly conserved protein containing a thioredoxin domain
CP971_RS13260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP971_RS13270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP971_RS13285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP971_RS13300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP971_RS13310	COG1595	DNA-templated transcription, initiation
CP971_RS13335	COG0183	Belongs to the thiolase family
CP971_RS13360	COG1136	(ABC) transporter
CP971_RS13365	COG0577	efflux transmembrane transporter activity
CP971_RS13370	COG1252	NADH dehydrogenase
CP971_RS13390	COG0148	phosphopyruvate hydratase activity
CP971_RS13395	COG1652	LysM domain
CP971_RS13400	COG2124	cytochrome p450
CP971_RS13455	COG4585	Histidine kinase
CP971_RS13460	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CP971_RS13470	COG1595	DNA-templated transcription, initiation
CP971_RS13480	COG0193	aminoacyl-tRNA hydrolase activity
CP971_RS13490	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CP971_RS13495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP971_RS13500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CP971_RS13515	COG1309	transcriptional regulator
CP971_RS13520	COG4106	trans-aconitate 2-methyltransferase activity
CP971_RS13530	COG2197	response regulator
CP971_RS13540	COG2204	response regulator
CP971_RS13550	COG1733	regulation of RNA biosynthetic process
CP971_RS13555	COG0655	NAD(P)H dehydrogenase (quinone) activity
CP971_RS13560	COG0477	Major facilitator Superfamily
CP971_RS13590	COG0488	(ABC) transporter
CP971_RS13595	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CP971_RS13600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CP971_RS13605	COG0084	hydrolase, TatD family'
CP971_RS13610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP971_RS13630	COG0768	penicillin binding
CP971_RS13640	COG0531	amino acid
CP971_RS13645	COG0768	penicillin binding
CP971_RS13650	COG0772	Belongs to the SEDS family
CP971_RS13660	COG1121	(ABC) transporter
CP971_RS13690	COG5650	phosphatidylinositol metabolic process
CP971_RS13705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP971_RS13710	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP971_RS13715	COG0315	cyclic pyranopterin monophosphate synthase activity
CP971_RS13725	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP971_RS13730	COG3706	GGDEF domain
CP971_RS13735	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CP971_RS13740	COG2366	antibiotic biosynthetic process
CP971_RS13745	COG3263	regulation of cellular component size
CP971_RS13770	COG1970	mechanosensitive ion channel activity
CP971_RS13825	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP971_RS13835	COG1131	(ABC) transporter
CP971_RS13850	COG0702	epimerase
CP971_RS13855	COG1733	regulation of RNA biosynthetic process
CP971_RS13905	COG1316	TRANSCRIPTIONal
CP971_RS13915	COG1013	pyruvate-flavodoxin oxidoreductase activity
CP971_RS13920	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CP971_RS13920	COG0674	pyruvate-flavodoxin oxidoreductase activity
CP971_RS13930	COG0142	geranyltranstransferase activity
CP971_RS13935	COG1007	ATP synthesis coupled electron transport
CP971_RS13945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP971_RS13950	COG0713	ATP synthesis coupled electron transport
CP971_RS13960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP971_RS13965	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP971_RS13970	COG1034	ATP synthesis coupled electron transport
CP971_RS13975	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP971_RS13985	COG0649	NAD binding
CP971_RS13990	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP971_RS13995	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP971_RS14010	COG2197	response regulator
CP971_RS14030	COG0110	maltose O-acetyltransferase activity
CP971_RS14055	COG2226	methyltransferase
CP971_RS14070	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP971_RS14080	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP971_RS14085	COG1278	Cold shock
CP971_RS14090	COG1301	dicarboxylic acid transport
CP971_RS14100	COG1609	Transcriptional regulator
CP971_RS14180	COG4821	SIS domain
CP971_RS14195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP971_RS14200	COG3629	intracellular signal transduction
CP971_RS14200	COG3903	Transcriptional regulator
CP971_RS14215	COG2378	regulation of single-species biofilm formation
CP971_RS14265	COG0641	radical SAM
CP971_RS14300	COG0259	pyridoxamine-phosphate oxidase activity
CP971_RS14310	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CP971_RS14325	COG2814	Major facilitator Superfamily
CP971_RS14330	COG1846	Transcriptional regulator
CP971_RS14345	COG1024	Enoyl-CoA hydratase
CP971_RS14345	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP971_RS14360	COG2252	PERMEase
CP971_RS14370	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP971_RS14385	COG2814	Major facilitator Superfamily
CP971_RS14395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP971_RS14400	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP971_RS14405	COG1278	Cold shock
CP971_RS14420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP971_RS14425	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP971_RS14430	COG1120	ATPase activity
CP971_RS14435	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CP971_RS14455	COG0667	Aldo Keto reductase
CP971_RS14515	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP971_RS14525	COG3226	Transcriptional regulator
CP971_RS14555	COG1061	Type III restriction enzyme res subunit
CP971_RS14560	COG3973	AAA domain
CP971_RS14575	COG1695	Transcriptional regulator
CP971_RS14590	COG0459	protein refolding
CP971_RS14595	COG1278	Cold shock
CP971_RS14610	COG0463	Glycosyl transferase, family 2
CP971_RS14645	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CP971_RS14665	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP971_RS14695	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CP971_RS14710	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP971_RS14710	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP971_RS14725	COG0302	gtp cyclohydrolase
CP971_RS14740	COG0037	tRNA processing
CP971_RS14750	COG2027	D-alanyl-D-alanine carboxypeptidase
CP971_RS14755	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP971_RS14760	COG3360	Dodecin
CP971_RS14775	COG1490	D-aminoacyl-tRNA deacylase activity
CP971_RS14780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP971_RS14790	COG3485	protocatechuate 3,4-dioxygenase
CP971_RS14810	COG2897	thiosulfate sulfurtransferase activity
CP971_RS14830	COG0745	RESPONSE REGULATOR receiver
CP971_RS14835	COG1609	Transcriptional regulator
CP971_RS14840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP971_RS14845	COG0745	RESPONSE REGULATOR receiver
CP971_RS14885	COG0741	lytic transglycosylase activity
CP971_RS14885	COG1196	nuclear chromosome segregation
CP971_RS14885	COG0739	heme binding
CP971_RS14890	COG0671	phosphoesterase, PA-phosphatase related
CP971_RS14910	COG1937	Protein conserved in bacteria
CP971_RS14920	COG0306	phosphate transporter
CP971_RS14940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CP971_RS14960	COG0456	acetyltransferase
CP971_RS15035	COG0579	oxidoreductase
CP971_RS15040	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CP971_RS15110	COG0642	Histidine kinase
CP971_RS15135	COG2124	cytochrome p450
CP971_RS15150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP971_RS15165	COG1968	undecaprenyl-diphosphatase activity
CP971_RS15170	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS15175	COG1595	DNA-templated transcription, initiation
CP971_RS15180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP971_RS15195	COG0028	Belongs to the TPP enzyme family
CP971_RS15200	COG1554	hydrolase, family 65, central catalytic
CP971_RS15220	COG1316	TRANSCRIPTIONal
CP971_RS15265	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CP971_RS15315	COG2124	cytochrome p450
CP971_RS15325	COG1131	(ABC) transporter
CP971_RS15340	COG2226	methyltransferase
CP971_RS15355	COG1309	transcriptional regulator
CP971_RS15365	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP971_RS15385	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS15415	COG0513	Belongs to the DEAD box helicase family
CP971_RS15425	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP971_RS15430	COG1993	acr, cog1993
CP971_RS15435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP971_RS15475	COG3693	PFAM glycoside hydrolase, family 10
CP971_RS15490	COG1063	alcohol dehydrogenase
CP971_RS15495	COG0583	DNA-binding transcription factor activity
CP971_RS15510	COG1643	Atp-dependent helicase
CP971_RS15530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP971_RS15540	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CP971_RS15555	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CP971_RS15580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP971_RS15585	COG2423	ornithine cyclodeaminase activity
CP971_RS15615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP971_RS15620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP971_RS15625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP971_RS15640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP971_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS15655	COG4106	trans-aconitate 2-methyltransferase activity
CP971_RS15680	COG2197	response regulator
CP971_RS15690	COG4106	trans-aconitate 2-methyltransferase activity
CP971_RS15695	COG3634	alkyl hydroperoxide reductase activity
CP971_RS15705	COG0667	Aldo Keto reductase
CP971_RS15725	COG1733	regulation of RNA biosynthetic process
CP971_RS15790	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP971_RS15795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP971_RS15800	COG1362	aminopeptidase activity
CP971_RS15810	COG1136	(ABC) transporter
CP971_RS15815	COG0577	efflux transmembrane transporter activity
CP971_RS15820	COG1960	acyl-CoA dehydrogenase activity
CP971_RS15845	COG2267	carboxylic ester hydrolase activity
CP971_RS15855	COG0154	amidase activity
CP971_RS15900	COG2372	response to copper ion
CP971_RS15905	COG2837	iron assimilation
CP971_RS15910	COG0077	Prephenate dehydratase
CP971_RS15915	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CP971_RS15920	COG0561	phosphatase activity
CP971_RS15930	COG2807	transmembrane transport
CP971_RS15940	COG1131	(ABC) transporter
CP971_RS15965	COG0561	phosphatase activity
CP971_RS15975	COG4988	ABC transporter
CP971_RS15980	COG1294	oxidase, subunit
CP971_RS15985	COG1271	oxidase subunit
CP971_RS16000	COG2205	protein histidine kinase activity
CP971_RS16005	COG0745	RESPONSE REGULATOR receiver
CP971_RS16015	COG1595	DNA-templated transcription, initiation
CP971_RS16030	COG0596	Alpha beta hydrolase
CP971_RS16035	COG0789	Transcriptional regulator
CP971_RS16070	COG4591	ABC-type transport system involved in lipoprotein release permease component
CP971_RS16070	COG1136	(ABC) transporter
CP971_RS16075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CP971_RS16075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CP971_RS16080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP971_RS16085	COG1609	Transcriptional regulator
CP971_RS16100	COG0667	Aldo Keto reductase
CP971_RS16120	COG0431	NADPH-dependent FMN reductase
CP971_RS16130	COG0583	DNA-binding transcription factor activity
CP971_RS16135	COG0346	lactoylglutathione lyase activity
CP971_RS16165	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CP971_RS16175	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CP971_RS16180	COG0662	Cupin 2, conserved barrel domain protein
CP971_RS16185	COG1950	PFAM Membrane protein of
CP971_RS16210	COG0022	dehydrogenase e1 component
CP971_RS16220	COG1522	sequence-specific DNA binding
CP971_RS16225	COG1309	transcriptional regulator
CP971_RS16240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP971_RS16290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP971_RS16305	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CP971_RS16305	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP971_RS16310	COG2197	response regulator
CP971_RS16325	COG1716	ATPase activity
CP971_RS16330	COG1716	ATPase activity
CP971_RS16345	COG0768	penicillin binding
CP971_RS16350	COG0515	serine threonine protein kinase
CP971_RS16355	COG3764	Sortase (surface protein transpeptidase)
CP971_RS16360	COG3764	Sortase (surface protein transpeptidase)
CP971_RS16385	COG0705	Rhomboid family
CP971_RS16385	COG0457	Tetratricopeptide repeat
CP971_RS16415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP971_RS16425	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP971_RS16435	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CP971_RS16440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CP971_RS16445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP971_RS16450	COG0592	DNA-directed DNA polymerase activity
CP971_RS16460	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CP971_RS16465	COG0594	ribonuclease P activity
CP971_RS16475	COG0706	membrane insertase activity
CP971_RS16485	COG0357	Ribosomal RNA small subunit methyltransferase G
CP971_RS16490	COG1192	Involved in chromosome partitioning
CP971_RS16505	COG3118	belongs to the thioredoxin family
CP971_RS16505	COG0492	ferredoxin-NADP+ reductase activity
CP971_RS16510	COG0492	ferredoxin-NADP+ reductase activity
CP971_RS16520	COG1595	DNA-templated transcription, initiation
CP971_RS16525	COG0515	serine threonine protein kinase
CP971_RS16525	COG2815	serine threonine protein kinase
CP971_RS16540	COG0617	tRNA 3'-terminal CCA addition
CP971_RS16595	COG0360	Binds together with S18 to 16S ribosomal RNA
CP971_RS16600	COG0629	single-stranded DNA binding
CP971_RS16605	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP971_RS16610	COG0359	binds to the 23S rRNA
CP971_RS16625	COG4552	Acetyltransferase involved in intracellular survival and related
CP971_RS16635	COG1482	cell wall glycoprotein biosynthetic process
CP971_RS16640	COG0463	Glycosyl transferase, family 2
CP971_RS16645	COG1733	regulation of RNA biosynthetic process
CP971_RS16650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CP971_RS16655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP971_RS16670	COG0303	'Molybdopterin
CP971_RS16695	COG0515	serine threonine protein kinase
CP971_RS16700	COG0515	serine threonine protein kinase
CP971_RS16720	COG0022	dehydrogenase e1 component
CP971_RS16725	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP971_RS16735	COG3135	benzoate transporter
CP971_RS16780	COG0151	Belongs to the GarS family
CP971_RS16795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CP971_RS16800	COG2197	response regulator
CP971_RS16835	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP971_RS16840	COG0047	phosphoribosylformylglycinamidine synthase activity
CP971_RS16845	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP971_RS16865	COG0191	fructose-bisphosphate aldolase activity
CP971_RS16870	COG0586	Pfam SNARE associated Golgi protein
CP971_RS16875	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CP971_RS16885	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CP971_RS16910	COG0542	response to heat
CP971_RS16950	COG0789	Transcriptional regulator
CP971_RS16955	COG0484	heat shock protein binding
CP971_RS16960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP971_RS16965	COG0443	Heat shock 70 kDa protein
CP971_RS16970	COG0247	lactate metabolic process
CP971_RS16970	COG2181	nitrate reductase activity
CP971_RS16975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP971_RS16985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP971_RS16990	COG0717	Belongs to the dCTP deaminase family
CP971_RS17015	COG2197	response regulator
CP971_RS17035	COG2084	Dehydrogenase
CP971_RS17040	COG0655	NAD(P)H dehydrogenase (quinone) activity
CP971_RS17060	COG0789	Transcriptional regulator
CP971_RS17065	COG4977	sequence-specific DNA binding
CP971_RS17070	COG1595	DNA-templated transcription, initiation
CP971_RS17080	COG0006	proline dipeptidase activity
CP971_RS17095	COG0653	protein targeting
CP971_RS17115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP971_RS17135	COG0277	FAD linked oxidase domain protein
CP971_RS17145	COG0259	pyridoxamine-phosphate oxidase activity
CP971_RS17150	COG5006	permease, DMT superfamily
CP971_RS17155	COG0318	PFAM AMP-dependent synthetase and ligase
CP971_RS17185	COG0667	Aldo Keto reductase
CP971_RS17210	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP971_RS17215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP971_RS17230	COG0438	transferase activity, transferring glycosyl groups
CP971_RS17240	COG2365	Tyrosine phosphatase family
CP971_RS17245	COG1191	sigma factor activity
CP971_RS17250	COG1191	sigma factor activity
CP971_RS17280	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CP971_RS17305	COG1881	PFAM PEBP family protein
CP971_RS17315	COG0477	Major facilitator Superfamily
CP971_RS17340	COG0640	Transcriptional regulator
CP971_RS17360	COG0477	Major facilitator Superfamily
CP971_RS17410	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP971_RS17555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP971_RS17565	COG0242	peptide deformylase activity
CP971_RS17655	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CP971_RS17660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CP971_RS17680	COG1595	DNA-templated transcription, initiation
CP971_RS17690	COG1566	PFAM secretion protein HlyD family protein
CP971_RS17705	COG0477	Major facilitator Superfamily
CP971_RS17735	COG1408	metallophosphoesterase
CP971_RS17750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP971_RS17760	COG0003	Pfam Anion-transporting ATPase
CP971_RS17785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP971_RS17820	COG1846	Transcriptional regulator
CP971_RS17855	COG2267	carboxylic ester hydrolase activity
CP971_RS17865	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP971_RS17870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP971_RS17875	COG0659	secondary active sulfate transmembrane transporter activity
CP971_RS17900	COG4974	Belongs to the 'phage' integrase family
CP971_RS17955	COG1205	dead DEAH box helicase
CP971_RS17955	COG1111	helicase
CP971_RS17960	COG1366	Belongs to the anti-sigma-factor antagonist family
CP971_RS17965	COG2172	sigma factor antagonist activity
CP971_RS17980	COG2890	protein-(glutamine-N5) methyltransferase activity
CP971_RS17990	COG1754	DNA topoisomerase type I activity
CP971_RS17990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP971_RS17995	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP971_RS18000	COG0470	DNA polymerase III
CP971_RS18065	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CP971_RS18120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP971_RS18125	COG2813	Specifically methylates the guanine in position
CP971_RS18130	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP971_RS18145	COG4221	oxidoreductase activity
CP971_RS18180	COG0494	nUDIX hydrolase
CP971_RS18210	COG0515	serine threonine protein kinase
CP971_RS18215	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP971_RS18225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP971_RS18235	COG2226	methyltransferase
CP971_RS18240	COG0477	Major facilitator Superfamily
CP971_RS18265	COG1309	transcriptional regulator
CP971_RS18275	COG0326	Molecular chaperone. Has ATPase activity
CP971_RS18310	COG4552	Acetyltransferase involved in intracellular survival and related
CP971_RS18335	COG0583	DNA-binding transcription factor activity
CP971_RS18340	COG2353	YceI-like domain
CP971_RS18345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP971_RS18355	COG1595	DNA-templated transcription, initiation
CP971_RS18360	COG4978	Transcriptional regulator
CP971_RS18360	COG0789	Transcriptional regulator
CP971_RS18385	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CP971_RS18395	COG0438	transferase activity, transferring glycosyl groups
CP971_RS18405	COG2211	Major facilitator Superfamily
CP971_RS18410	COG0588	phosphoglycerate mutase activity
CP971_RS18415	COG3397	chitin binding
CP971_RS18435	COG0745	RESPONSE REGULATOR receiver
CP971_RS18450	COG1329	Transcriptional regulator
CP971_RS18455	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CP971_RS18460	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CP971_RS18470	COG0215	cysteine-tRNA ligase activity
CP971_RS18475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP971_RS18485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CP971_RS18495	COG3842	ATPase activity
CP971_RS18520	COG2815	serine threonine protein kinase
CP971_RS18520	COG0515	serine threonine protein kinase
CP971_RS18525	COG2205	protein histidine kinase activity
CP971_RS18530	COG0745	RESPONSE REGULATOR receiver
CP971_RS18555	COG1132	(ABC) transporter
CP971_RS18575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP971_RS18580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP971_RS18585	COG0142	geranyltranstransferase activity
CP971_RS18615	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CP971_RS18640	COG1309	transcriptional regulator
CP971_RS18645	COG0739	heme binding
CP971_RS18665	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CP971_RS18685	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CP971_RS18695	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CP971_RS18700	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CP971_RS18705	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CP971_RS18715	COG2197	response regulator
CP971_RS18720	COG4585	Histidine kinase
CP971_RS18730	COG0649	NAD binding
CP971_RS18755	COG0584	glycerophosphoryl diester phosphodiesterase
CP971_RS18760	COG0248	Ppx GppA phosphatase
CP971_RS18765	COG1082	Xylose isomerase domain protein TIM barrel
CP971_RS18770	COG2226	methyltransferase
CP971_RS18775	COG0129	dihydroxy-acid dehydratase activity
CP971_RS18795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP971_RS18805	COG0123	including yeast histone deacetylase and acetoin utilization protein
CP971_RS18855	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CP971_RS18860	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CP971_RS18865	COG0181	hydroxymethylbilane synthase activity
CP971_RS18870	COG1648	precorrin-2 dehydrogenase activity
CP971_RS18870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP971_RS18875	COG0113	porphobilinogen synthase activity
CP971_RS19010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CP971_RS19020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CP971_RS19085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP971_RS19090	COG0406	alpha-ribazole phosphatase activity
CP971_RS19095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP971_RS19100	COG0785	Cytochrome C biogenesis protein
CP971_RS19105	COG1333	cytochrome c biogenesis protein
CP971_RS19110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP971_RS19140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP971_RS19150	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CP971_RS19155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CP971_RS19160	COG0509	glycine decarboxylation via glycine cleavage system
CP971_RS19200	COG0163	prenyltransferase activity
CP971_RS19205	COG1522	sequence-specific DNA binding
CP971_RS19210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP971_RS19215	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP971_RS19225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP971_RS19230	COG1309	transcriptional regulator
CP971_RS19235	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP971_RS19235	COG0515	serine threonine protein kinase
CP971_RS19240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CP971_RS19245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP971_RS19255	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP971_RS19260	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP971_RS19265	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP971_RS19270	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP971_RS19275	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP971_RS19285	COG0713	ATP synthesis coupled electron transport
CP971_RS19295	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP971_RS19300	COG1007	ATP synthesis coupled electron transport
CP971_RS19305	COG0501	Belongs to the peptidase M48B family
CP971_RS19320	COG0501	Belongs to the peptidase M48B family
CP971_RS19325	COG2130	NADP-dependent
CP971_RS19330	COG0583	DNA-binding transcription factor activity
CP971_RS19355	COG1666	GTP binding
CP971_RS19365	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CP971_RS19395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP971_RS19400	COG2030	dehydratase
CP971_RS19415	COG0477	Major facilitator Superfamily
CP971_RS19420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CP971_RS19425	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP971_RS19430	COG0436	Aminotransferase
CP971_RS19445	COG0250	Participates in transcription elongation, termination and antitermination
CP971_RS19450	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CP971_RS19455	COG0081	regulation of translation
CP971_RS19480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CP971_RS19485	COG0222	ribosome binding
CP971_RS19490	COG0085	RNA polymerase activity
CP971_RS19495	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CP971_RS19535	COG4585	Histidine kinase
CP971_RS19540	COG2197	response regulator
CP971_RS19560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP971_RS19565	COG2124	cytochrome p450
CP971_RS19585	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CP971_RS19590	COG1397	ADP-ribosylglycohydrolase
CP971_RS19620	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CP971_RS19625	COG0049	tRNA binding
CP971_RS19630	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP971_RS19635	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP971_RS19640	COG0463	Glycosyl transferase, family 2
CP971_RS19680	COG0051	transcription antitermination factor activity, RNA binding
CP971_RS19685	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CP971_RS19690	COG0088	Forms part of the polypeptide exit tunnel
CP971_RS19700	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CP971_RS19705	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CP971_RS19710	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CP971_RS19715	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CP971_RS19720	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CP971_RS19725	COG0255	Belongs to the universal ribosomal protein uL29 family
CP971_RS19730	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CP971_RS19735	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CP971_RS19740	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CP971_RS19745	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CP971_RS19750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP971_RS19755	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CP971_RS19760	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CP971_RS19765	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CP971_RS19770	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CP971_RS19775	COG1841	ribosomal large subunit assembly
CP971_RS19780	COG0200	Binds to the 23S rRNA
CP971_RS19790	COG0563	adenylate kinase activity
CP971_RS19805	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CP971_RS19810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CP971_RS19815	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CP971_RS19820	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CP971_RS19825	COG0202	RNA polymerase activity
CP971_RS19830	COG0203	ribosomal protein L17
CP971_RS19835	COG0101	tRNA pseudouridine synthase activity
CP971_RS19840	COG0488	(ABC) transporter
CP971_RS19845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CP971_RS19850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CP971_RS19855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP971_RS19860	COG1072	(Pantothenic acid kinase))
CP971_RS19865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP971_RS19880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP971_RS19890	COG0802	atpase or kinase
CP971_RS19915	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP971_RS19925	COG0726	polysaccharide deacetylase
CP971_RS19935	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CP971_RS19945	COG0583	DNA-binding transcription factor activity
CP971_RS19960	COG1595	DNA-templated transcription, initiation
CP971_RS19970	COG0516	GMP reductase activity
CP971_RS19995	COG0515	serine threonine protein kinase
CP971_RS19995	COG2815	serine threonine protein kinase
CP971_RS20000	COG1012	belongs to the aldehyde dehydrogenase family
CP971_RS20015	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CP971_RS20015	COG0519	Catalyzes the synthesis of GMP from XMP
CP971_RS20040	COG2197	response regulator
CP971_RS20055	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP971_RS20055	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP971_RS20070	COG0714	Associated with various cellular activities
CP971_RS20080	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP971_RS20085	COG0045	succinate-CoA ligase (ADP-forming) activity
CP971_RS20115	COG0138	bifunctional purine biosynthesis protein purh
CP971_RS20125	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP971_RS20135	COG0039	L-malate dehydrogenase activity
CP971_RS20140	COG1253	flavin adenine dinucleotide binding
CP971_RS20145	COG0180	Tryptophanyl-tRNA synthetase
CP971_RS20155	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP971_RS20160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP971_RS20165	COG1216	Glycosyl transferase, family 2
CP971_RS20170	COG1295	ribonuclease BN
CP971_RS20175	COG1686	Belongs to the peptidase S11 family
CP971_RS20195	COG1053	succinate dehydrogenase
CP971_RS20205	COG2009	succinate dehydrogenase
CP971_RS20225	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP971_RS20225	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP971_RS20230	COG1473	amidohydrolase
CP971_RS20230	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP971_RS20235	COG1744	ABC transporter substrate-binding protein PnrA-like
CP971_RS20240	COG3845	ABC transporter
CP971_RS20245	COG4603	Belongs to the binding-protein-dependent transport system permease family
CP971_RS20250	COG1079	Belongs to the binding-protein-dependent transport system permease family
CP971_RS20270	COG2814	Major facilitator Superfamily
CP971_RS20275	COG0583	DNA-binding transcription factor activity
CP971_RS20280	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP971_RS20305	COG0384	phenazine biosynthesis protein PhzF
CP971_RS20320	COG2205	protein histidine kinase activity
CP971_RS20325	COG0745	RESPONSE REGULATOR receiver
CP971_RS20330	COG1595	DNA-templated transcription, initiation
CP971_RS20345	COG1012	belongs to the aldehyde dehydrogenase family
CP971_RS20350	COG1012	belongs to the aldehyde dehydrogenase family
CP971_RS20365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP971_RS20390	COG4770	biotin carboxylase activity
CP971_RS20400	COG0424	maF-like protein
CP971_RS20410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP971_RS20420	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP971_RS20435	COG1309	transcriptional regulator
CP971_RS20445	COG2986	histidine ammonia-lyase
CP971_RS20480	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CP971_RS20495	COG1228	amidohydrolase
CP971_RS20560	COG3104	oligopeptide transport
CP971_RS20565	COG0745	RESPONSE REGULATOR receiver
CP971_RS20570	COG2205	protein histidine kinase activity
CP971_RS20605	COG1832	CoA-binding protein
CP971_RS20625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP971_RS20635	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS20665	COG1045	serine acetyltransferase
CP971_RS20670	COG1316	TRANSCRIPTIONal
CP971_RS20675	COG0431	NADPH-dependent FMN reductase
CP971_RS20680	COG0577	efflux transmembrane transporter activity
CP971_RS20680	COG1136	(ABC) transporter
CP971_RS20685	COG0577	efflux transmembrane transporter activity
CP971_RS20695	COG1316	TRANSCRIPTIONal
CP971_RS20700	COG1316	TRANSCRIPTIONal
CP971_RS20720	COG0778	Nitroreductase
CP971_RS20720	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CP971_RS20725	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP971_RS20760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP971_RS20765	COG2835	tetraacyldisaccharide 4'-kinase activity
CP971_RS20780	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CP971_RS20825	COG3795	YCII-related domain
CP971_RS20830	COG4941	Belongs to the sigma-70 factor family
CP971_RS20840	COG0714	Associated with various cellular activities
CP971_RS20860	COG0745	RESPONSE REGULATOR receiver
CP971_RS20865	COG5002	protein histidine kinase activity
CP971_RS20865	COG5000	phosphorelay sensor kinase activity
CP971_RS20870	COG0823	Involved in the tonB-independent uptake of proteins
CP971_RS20880	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP971_RS20890	COG3214	Protein conserved in bacteria
CP971_RS20900	COG0653	protein targeting
CP971_RS20925	COG1012	belongs to the aldehyde dehydrogenase family
CP971_RS20935	COG1674	ftsk spoiiie
CP971_RS20940	COG0515	serine threonine protein kinase
CP971_RS20945	COG0515	serine threonine protein kinase
CP971_RS20950	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP971_RS20960	COG2884	Cell division ATP-binding protein ftsE
CP971_RS20970	COG0793	Belongs to the peptidase S41A family
CP971_RS20975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CP971_RS20985	COG3973	AAA domain
CP971_RS20995	COG0776	regulation of translation
CP971_RS21000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP971_RS21005	COG1678	Uncharacterized ACR, COG1678
CP971_RS21015	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP971_RS21025	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP971_RS21035	COG2076	Multidrug Resistance protein
CP971_RS21055	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP971_RS21060	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CP971_RS21080	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP971_RS21095	COG0745	RESPONSE REGULATOR receiver
CP971_RS21105	COG5650	phosphatidylinositol metabolic process
CP971_RS21130	COG1515	deoxyribonuclease V activity
CP971_RS21185	COG1335	isochorismatase
CP971_RS21195	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CP971_RS21205	COG1113	amino acid transport
CP971_RS21235	COG1234	tRNA 3'-trailer cleavage
CP971_RS21245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP971_RS21250	COG1263	PTS System
CP971_RS21255	COG1263	PTS System
CP971_RS21260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP971_RS21265	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CP971_RS21275	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CP971_RS21305	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CP971_RS21335	COG2186	Transcriptional regulator
CP971_RS21395	COG1131	(ABC) transporter
CP971_RS21400	COG1216	Glycosyl transferase, family 2
CP971_RS21405	COG2733	membrane
CP971_RS21410	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP971_RS21485	COG1309	transcriptional regulator
CP971_RS21495	COG0702	epimerase
CP971_RS21510	COG0640	Transcriptional regulator
CP971_RS21555	COG0673	inositol 2-dehydrogenase activity
CP971_RS21570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP971_RS21615	COG0559	Belongs to the binding-protein-dependent transport system permease family
CP971_RS21640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP971_RS21665	COG1764	response to oxidative stress
CP971_RS21670	COG1605	Chorismate mutase
CP971_RS21670	COG0287	Prephenate dehydrogenase
CP971_RS21675	COG0681	Belongs to the peptidase S26 family
CP971_RS21685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP971_RS21735	COG0583	DNA-binding transcription factor activity
CP971_RS21740	COG5640	endopeptidase activity
CP971_RS21745	COG5640	endopeptidase activity
CP971_RS21755	COG3511	phospholipase C
CP971_RS21770	COG0793	Belongs to the peptidase S41A family
CP971_RS21770	COG4946	Tricorn protease homolog
CP971_RS21780	COG2814	Major facilitator Superfamily
CP971_RS21790	COG4977	sequence-specific DNA binding
CP971_RS21805	COG0025	NhaP-type Na H and K H
CP971_RS21810	COG0166	Belongs to the GPI family
CP971_RS21850	COG0588	phosphoglycerate mutase activity
CP971_RS21890	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CP971_RS21915	COG1960	acyl-CoA dehydrogenase activity
CP971_RS21930	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP971_RS21935	COG1309	transcriptional regulator
CP971_RS21960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP971_RS21965	COG0180	Tryptophanyl-tRNA synthetase
CP971_RS21970	COG1619	proteins homologs of microcin C7 resistance protein MccF
CP971_RS22005	COG2197	response regulator
CP971_RS22020	COG1739	Uncharacterized protein family UPF0029
CP971_RS22040	COG0583	DNA-binding transcription factor activity
CP971_RS22065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP971_RS22080	COG1012	belongs to the aldehyde dehydrogenase family
CP971_RS22085	COG0702	epimerase
CP971_RS22095	COG0750	zinc metalloprotease
CP971_RS22100	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CP971_RS22115	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
CP971_RS22125	COG0779	Required for maturation of 30S ribosomal subunits
CP971_RS22140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CP971_RS22150	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CP971_RS22155	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CP971_RS22160	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CP971_RS22175	COG0455	bacterial-type flagellum organization
CP971_RS22200	COG4842	Belongs to the WXG100 family
CP971_RS22230	COG1674	ftsk spoiiie
CP971_RS22240	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CP971_RS22245	COG1185	polyribonucleotide nucleotidyltransferase activity
CP971_RS22250	COG0612	Peptidase, M16
CP971_RS22255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CP971_RS22265	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CP971_RS22270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP971_RS22275	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CP971_RS22325	COG0569	domain protein
CP971_RS22330	COG0531	amino acid
CP971_RS22335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CP971_RS22365	COG0189	ligase activity
CP971_RS22395	COG3973	AAA domain
CP971_RS22405	COG2171	N-acyltransferase activity
CP971_RS22415	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CP971_RS22420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP971_RS22450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP971_RS22460	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP971_RS22465	COG1113	amino acid transport
CP971_RS22510	COG0544	peptidyl-prolyl cis-trans isomerase activity
CP971_RS22515	COG0740	serine-type endopeptidase activity
CP971_RS22520	COG0740	serine-type endopeptidase activity
CP971_RS22525	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CP971_RS22540	COG0525	valine-tRNA ligase activity
CP971_RS22550	COG0285	dihydrofolate synthase activity
CP971_RS22560	COG0105	UTP biosynthetic process
CP971_RS22565	COG1077	Cell shape determining protein MreB Mrl
CP971_RS22590	COG0772	Belongs to the SEDS family
CP971_RS22610	COG1530	ribonuclease E activity
CP971_RS22615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CP971_RS22620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CP971_RS22625	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CP971_RS22635	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CP971_RS22645	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CP971_RS22660	COG0501	Belongs to the peptidase M48B family
CP971_RS22665	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CP971_RS22675	COG0799	negative regulation of ribosome biogenesis
CP971_RS22680	COG0406	alpha-ribazole phosphatase activity
CP971_RS22700	COG0477	Major facilitator Superfamily
CP971_RS22715	COG0495	leucyl-tRNA aminoacylation
CP971_RS22725	COG1307	EDD domain protein, DegV family
CP971_RS22730	COG1555	photosystem II stabilization
CP971_RS22745	COG1335	isochorismatase
CP971_RS22775	COG0268	Binds directly to 16S ribosomal RNA
CP971_RS22780	COG2329	Antibiotic biosynthesis monooxygenase
CP971_RS22785	COG0481	GTPase activity
CP971_RS22825	COG0501	Belongs to the peptidase M48B family
CP971_RS22830	COG1420	regulation of RNA biosynthetic process
CP971_RS22835	COG0484	heat shock protein binding
CP971_RS22845	COG4946	Tricorn protease homolog
CP971_RS22845	COG0793	Belongs to the peptidase S41A family
CP971_RS22855	COG0537	adenosine 5'-monophosphoramidase activity
CP971_RS22860	COG1234	tRNA 3'-trailer cleavage
CP971_RS22870	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CP971_RS22900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CP971_RS22915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP971_RS22925	COG1381	Involved in DNA repair and RecF pathway recombination
CP971_RS22930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP971_RS22940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP971_RS22945	COG1121	(ABC) transporter
CP971_RS22955	COG0423	glycine-tRNA ligase activity
CP971_RS22985	COG2378	regulation of single-species biofilm formation
CP971_RS23020	COG0477	Major facilitator Superfamily
CP971_RS23065	COG0574	Belongs to the PEP-utilizing enzyme family
CP971_RS23065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP971_RS23070	COG4290	ribonuclease
CP971_RS23105	COG2755	lipolytic protein G-D-S-L family
CP971_RS23110	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CP971_RS23115	COG0358	DNA primase activity
CP971_RS23120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP971_RS23130	COG1070	Carbohydrate kinase
CP971_RS23180	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CP971_RS23185	COG1316	TRANSCRIPTIONal
CP971_RS23195	COG2130	NADP-dependent
CP971_RS23205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP971_RS23210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP971_RS23215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP971_RS23240	COG0789	Transcriptional regulator
CP971_RS23245	COG0667	Aldo Keto reductase
CP971_RS23255	COG2378	regulation of single-species biofilm formation
CP971_RS23280	COG2197	response regulator
CP971_RS23285	COG4585	Histidine kinase
CP971_RS23290	COG1309	transcriptional regulator
CP971_RS23295	COG0477	Major facilitator Superfamily
CP971_RS23350	COG1358	cellular component organization or biogenesis
CP971_RS23375	COG0582	viral genome integration into host DNA
CP971_RS23465	COG1595	DNA-templated transcription, initiation
CP971_RS23480	COG0542	response to heat
CP971_RS23490	COG4585	Histidine kinase
CP971_RS23495	COG2197	response regulator
CP971_RS23505	COG1136	(ABC) transporter
CP971_RS23510	COG0577	efflux transmembrane transporter activity
CP971_RS23515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP971_RS23525	COG1309	transcriptional regulator
CP971_RS23545	COG1960	acyl-CoA dehydrogenase activity
CP971_RS23590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP971_RS23600	COG3483	tryptophan 2,3-dioxygenase activity
CP971_RS23605	COG1522	sequence-specific DNA binding
CP971_RS23615	COG2095	MarC family integral membrane protein
CP971_RS23685	COG1472	Belongs to the glycosyl hydrolase 3 family
CP971_RS23695	COG3845	ABC transporter
CP971_RS23715	COG1309	transcriptional regulator
CP971_RS23720	COG0438	transferase activity, transferring glycosyl groups
CP971_RS23740	COG0860	N-Acetylmuramoyl-L-alanine amidase
CP971_RS23760	COG2267	carboxylic ester hydrolase activity
CP971_RS23765	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CP971_RS23780	COG3022	response to hydroperoxide
CP971_RS23790	COG0557	exoribonuclease II activity
CP971_RS23815	COG1695	Transcriptional regulator
CP971_RS23865	COG1994	Peptidase M50
CP971_RS23885	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CP971_RS23890	COG0477	Major facilitator Superfamily
CP971_RS23895	COG1309	transcriptional regulator
CP971_RS23910	COG0475	glutathione-regulated potassium exporter activity
CP971_RS23925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP971_RS23935	COG0367	asparagine synthase
CP971_RS23990	COG0318	PFAM AMP-dependent synthetase and ligase
CP971_RS24015	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CP971_RS24025	COG3629	intracellular signal transduction
CP971_RS24040	COG0174	glutamine synthetase
CP971_RS24045	COG3764	Sortase (surface protein transpeptidase)
CP971_RS24060	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CP971_RS24090	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS24165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CP971_RS24170	COG0321	lipoyl(octanoyl) transferase activity
CP971_RS24175	COG2508	Transcriptional regulator
CP971_RS24185	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS24220	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP971_RS24225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP971_RS24230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CP971_RS24235	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CP971_RS24240	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP971_RS24275	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CP971_RS24315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP971_RS24330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CP971_RS24335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP971_RS24345	COG1376	ErfK ybiS ycfS ynhG family protein
CP971_RS24355	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP971_RS24360	COG0723	plastoquinol--plastocyanin reductase activity
CP971_RS24365	COG2010	Cytochrome c
CP971_RS24370	COG1845	cytochrome c oxidase, subunit III
CP971_RS24380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP971_RS24455	COG0003	Pfam Anion-transporting ATPase
CP971_RS24465	COG1940	carbohydrate kinase activity
CP971_RS24495	COG2197	response regulator
CP971_RS24505	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP971_RS24510	COG0243	molybdopterin cofactor binding
CP971_RS24515	COG2193	ferroxidase activity
CP971_RS24525	COG0515	serine threonine protein kinase
CP971_RS24525	COG2815	serine threonine protein kinase
CP971_RS24530	COG2022	thiamine diphosphate biosynthetic process
CP971_RS24540	COG2022	thiamine diphosphate biosynthetic process
CP971_RS24540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP971_RS24555	COG0352	thiamine-phosphate diphosphorylase activity
CP971_RS24560	COG0142	geranyltranstransferase activity
CP971_RS24590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP971_RS24610	COG0714	Associated with various cellular activities
CP971_RS24620	COG0275	rRNA processing
CP971_RS24635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP971_RS24645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP971_RS24650	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP971_RS24660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP971_RS24685	COG1799	cell septum assembly
CP971_RS24700	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CP971_RS24710	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CP971_RS24745	COG0640	Transcriptional regulator
CP971_RS24755	COG1522	sequence-specific DNA binding
CP971_RS24765	COG0590	tRNA wobble adenosine to inosine editing
CP971_RS24770	COG5504	Zn-dependent protease
CP971_RS24775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP971_RS24790	COG0587	DNA-directed DNA polymerase activity
CP971_RS24800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP971_RS24835	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CP971_RS24845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CP971_RS24850	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP971_RS24855	COG0131	Imidazoleglycerol-phosphate dehydratase
CP971_RS24860	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CP971_RS24865	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CP971_RS24870	COG0251	oxidation-reduction process
CP971_RS24875	COG0107	imidazoleglycerol-phosphate synthase activity
CP971_RS24900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CP971_RS24905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP971_RS24930	COG0134	indole-3-glycerol-phosphate synthase activity
CP971_RS24935	COG0133	tryptophan synthase activity
CP971_RS24940	COG0159	tryptophan synthase activity
CP971_RS24960	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CP971_RS24970	COG0070	glutamate synthase
CP971_RS24970	COG0069	glutamate synthase activity
CP971_RS24970	COG0067	glutamate synthase
CP971_RS24985	COG1012	belongs to the aldehyde dehydrogenase family
CP971_RS24990	COG2207	Transcriptional regulator
CP971_RS25005	COG0737	Belongs to the 5'-nucleotidase family
CP971_RS25070	COG2050	protein possibly involved in aromatic compounds catabolism
CP971_RS25100	COG1643	Atp-dependent helicase
CP971_RS25105	COG2226	methyltransferase
CP971_RS25115	COG2409	Drug exporters of the RND superfamily
CP971_RS25130	COG0237	dephospho-CoA kinase activity
CP971_RS25145	COG0504	CTP synthase activity
CP971_RS25165	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP971_RS25190	COG4221	oxidoreductase activity
CP971_RS25200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP971_RS25275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP971_RS25285	COG0789	Transcriptional regulator
CP971_RS25290	COG3959	Transketolase, thiamine diphosphate binding domain
CP971_RS25295	COG3958	Transketolase
CP971_RS25335	COG0726	polysaccharide deacetylase
CP971_RS25345	COG2409	Drug exporters of the RND superfamily
CP971_RS25350	COG1278	Cold shock
CP971_RS25390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP971_RS25395	COG1116	anion transmembrane transporter activity
CP971_RS25420	COG0529	Catalyzes the synthesis of activated sulfate
CP971_RS25425	COG0175	sulfate reduction
CP971_RS25460	COG1162	GTPase activity
CP971_RS25470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP971_RS25490	COG0193	aminoacyl-tRNA hydrolase activity
CP971_RS25520	COG1309	transcriptional regulator
CP971_RS25525	COG2957	Belongs to the agmatine deiminase family
CP971_RS25530	COG0804	urea catabolic process
CP971_RS25535	COG0831	urea catabolic process
CP971_RS25535	COG0832	Belongs to the urease beta subunit family
CP971_RS25570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP971_RS25570	COG1213	nucleotidyl transferase
CP971_RS25575	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP971_RS25585	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP971_RS25585	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CP971_RS25605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP971_RS25610	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS25660	COG4977	sequence-specific DNA binding
CP971_RS25695	COG1794	racemase activity, acting on amino acids and derivatives
CP971_RS25705	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CP971_RS25715	COG0681	Belongs to the peptidase S26 family
CP971_RS25735	COG1742	UPF0060 membrane protein
CP971_RS25740	COG0436	Aminotransferase
CP971_RS25760	COG1357	PFAM Pentapeptide repeats (8 copies)
CP971_RS25770	COG1309	transcriptional regulator
CP971_RS25780	COG0583	DNA-binding transcription factor activity
CP971_RS25820	COG2124	cytochrome p450
CP971_RS25825	COG2197	response regulator
CP971_RS25830	COG4585	Histidine kinase
CP971_RS25835	COG0577	efflux transmembrane transporter activity
CP971_RS25835	COG1136	(ABC) transporter
CP971_RS25840	COG1136	(ABC) transporter
CP971_RS25840	COG0577	efflux transmembrane transporter activity
CP971_RS25845	COG0181	hydroxymethylbilane synthase activity
CP971_RS25860	COG0242	peptide deformylase activity
CP971_RS25910	COG0667	Aldo Keto reductase
CP971_RS25920	COG0778	Nitroreductase
CP971_RS25925	COG0488	(ABC) transporter
CP971_RS25935	COG0488	(ABC) transporter
CP971_RS25945	COG2197	response regulator
CP971_RS25950	COG4585	Histidine kinase
CP971_RS25980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP971_RS25985	COG1960	acyl-CoA dehydrogenase activity
CP971_RS25990	COG0183	Belongs to the thiolase family
CP971_RS25995	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP971_RS25995	COG1024	Enoyl-CoA hydratase
CP971_RS26010	COG2197	response regulator
CP971_RS26020	COG0577	efflux transmembrane transporter activity
CP971_RS26020	COG1136	(ABC) transporter
CP971_RS26030	COG0789	Transcriptional regulator
CP971_RS26035	COG0583	DNA-binding transcription factor activity
CP971_RS26060	COG2318	DinB family
CP971_RS26085	COG0587	DNA-directed DNA polymerase activity
CP971_RS26100	COG2197	response regulator
CP971_RS26105	COG0318	PFAM AMP-dependent synthetase and ligase
CP971_RS26110	COG0789	Transcriptional regulator
CP971_RS26130	COG2910	NAD(P)H-binding
CP971_RS26135	COG3384	dioxygenase
CP971_RS26155	COG1609	Transcriptional regulator
CP971_RS26180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP971_RS26235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP971_RS26270	COG2259	Doxx family
CP971_RS26280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP971_RS26290	COG2837	iron assimilation
CP971_RS26305	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP971_RS26320	COG1309	transcriptional regulator
CP971_RS26330	COG0640	Transcriptional regulator
CP971_RS26360	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CP971_RS26370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP971_RS26400	COG0667	Aldo Keto reductase
CP971_RS26405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP971_RS26410	COG0598	Magnesium transport protein CorA
CP971_RS26430	COG0215	cysteine-tRNA ligase activity
CP971_RS26450	COG0646	methionine synthase
CP971_RS26450	COG1410	methionine synthase
CP971_RS26465	COG2197	response regulator
CP971_RS26475	COG0517	IMP dehydrogenase activity
CP971_RS26475	COG1994	Peptidase M50
CP971_RS26495	COG1222	aaa ATPase
CP971_RS26500	COG4122	O-methyltransferase activity
CP971_RS26510	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP971_RS26515	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP971_RS26520	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP971_RS26525	COG0545	Peptidyl-prolyl cis-trans isomerase
CP971_RS26530	COG0545	Peptidyl-prolyl cis-trans isomerase
CP971_RS26555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP971_RS26560	COG0805	protein transport
CP971_RS26565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP971_RS26585	COG3938	Belongs to the proline racemase family
CP971_RS26590	COG1012	belongs to the aldehyde dehydrogenase family
CP971_RS26605	COG1309	transcriptional regulator
CP971_RS26610	COG2084	Dehydrogenase
CP971_RS26615	COG1802	Transcriptional regulator
CP971_RS26625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP971_RS26635	COG4585	Histidine kinase
CP971_RS26640	COG2197	response regulator
CP971_RS26645	COG2070	2-Nitropropane dioxygenase
CP971_RS26650	COG0006	proline dipeptidase activity
CP971_RS26655	COG0747	negative chemotaxis
CP971_RS26660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP971_RS26665	COG0601	transmembrane transport
CP971_RS26670	COG0444	Belongs to the ABC transporter superfamily
CP971_RS26675	COG4608	Belongs to the ABC transporter superfamily
CP971_RS26685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP971_RS26705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP971_RS26715	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP971_RS26720	COG0174	glutamine synthetase
CP971_RS26730	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS26760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CP971_RS26765	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CP971_RS26770	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CP971_RS26775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP971_RS26780	COG5002	protein histidine kinase activity
CP971_RS26785	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CP971_RS26790	COG0072	phenylalanine-tRNA ligase activity
CP971_RS26790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP971_RS26795	COG1725	Transcriptional regulator
CP971_RS26800	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CP971_RS26815	COG4213	ABC transporter substrate-binding protein
CP971_RS26825	COG0300	oxidoreductase activity
CP971_RS26860	COG2813	Specifically methylates the guanine in position
CP971_RS26865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP971_RS26870	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CP971_RS26875	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CP971_RS26880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP971_RS26885	COG1438	arginine binding
CP971_RS26890	COG0165	Argininosuccinate lyase
CP971_RS26905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP971_RS26910	COG2011	ABC-type metal ion transport system permease component
CP971_RS26915	COG1464	Belongs to the NlpA lipoprotein family
CP971_RS26930	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP971_RS26935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP971_RS26935	COG1648	precorrin-2 dehydrogenase activity
CP971_RS26940	COG3290	protein histidine kinase activity
CP971_RS26950	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP971_RS26950	COG0515	serine threonine protein kinase
CP971_RS26990	COG0512	Glutamine amidotransferase of anthranilate synthase
CP971_RS26990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP971_RS27035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP971_RS27050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CP971_RS27080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP971_RS27090	COG0438	transferase activity, transferring glycosyl groups
CP971_RS27105	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CP971_RS27110	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CP971_RS27115	COG0217	transcriptional regulatory protein
CP971_RS27120	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CP971_RS27125	COG0632	four-way junction helicase activity
CP971_RS27130	COG2255	four-way junction helicase activity
CP971_RS27140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP971_RS27145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP971_RS27150	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CP971_RS27155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP971_RS27160	COG1196	nuclear chromosome segregation
CP971_RS27165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP971_RS27175	COG0124	histidyl-tRNA synthetase
CP971_RS27180	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CP971_RS27190	COG2326	polyphosphate kinase activity
CP971_RS27200	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CP971_RS27225	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP971_RS27230	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CP971_RS27245	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP971_RS27250	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP971_RS27255	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP971_RS27260	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CP971_RS27265	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CP971_RS27285	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CP971_RS27300	COG0006	proline dipeptidase activity
CP971_RS27305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CP971_RS27310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CP971_RS27330	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CP971_RS27335	COG0540	Belongs to the ATCase OTCase family
CP971_RS27340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP971_RS27350	COG0505	Belongs to the CarA family
CP971_RS27355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP971_RS27360	COG0167	dihydroorotate dehydrogenase activity
CP971_RS27365	COG0284	orotidine-5'-phosphate decarboxylase activity
CP971_RS27375	COG0194	GDP metabolic process
CP971_RS27410	COG0242	peptide deformylase activity
CP971_RS27415	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP971_RS27475	COG0640	Transcriptional regulator
CP971_RS27500	COG0596	Alpha beta hydrolase
CP971_RS27515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP971_RS27545	COG0667	Aldo Keto reductase
CP971_RS27570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CP971_RS27675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP971_RS27690	COG4948	Mandelate Racemase Muconate Lactonizing
CP971_RS27695	COG1846	Transcriptional regulator
CP971_RS27715	COG0640	Transcriptional regulator
CP971_RS27720	COG2814	Major facilitator Superfamily
CP971_RS27735	COG0656	L-ascorbic acid biosynthetic process
CP971_RS27740	COG2814	Major facilitator Superfamily
CP971_RS27755	COG2837	iron assimilation
CP971_RS27790	COG1937	Protein conserved in bacteria
CP971_RS27805	COG0701	Predicted permease
CP971_RS27865	COG0596	Alpha beta hydrolase
CP971_RS27870	COG1733	regulation of RNA biosynthetic process
CP971_RS27875	COG0702	epimerase
CP971_RS27890	COG1178	ABC-type Fe3 transport system permease component
CP971_RS27895	COG3842	ATPase activity
CP971_RS27905	COG0515	serine threonine protein kinase
CP971_RS27925	COG0443	Heat shock 70 kDa protein
CP971_RS27940	COG0318	PFAM AMP-dependent synthetase and ligase
CP971_RS27960	COG3209	COG3209 Rhs family protein
CP971_RS28010	COG2132	Multicopper oxidase
CP971_RS28025	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CP971_RS28080	COG0740	serine-type endopeptidase activity
CP971_RS28085	COG0740	serine-type endopeptidase activity
CP971_RS28090	COG1396	sequence-specific DNA binding
CP971_RS28100	COG2409	Drug exporters of the RND superfamily
CP971_RS28120	COG3511	phospholipase C
CP971_RS28185	COG0395	ABC-type sugar transport system, permease component
CP971_RS28200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP971_RS28205	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS28230	COG0009	L-threonylcarbamoyladenylate synthase
CP971_RS28240	COG0516	GMP reductase activity
CP971_RS28240	COG0517	IMP dehydrogenase activity
CP971_RS28250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CP971_RS28265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP971_RS28275	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CP971_RS28280	COG2814	Major facilitator Superfamily
CP971_RS28305	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CP971_RS28310	COG2197	response regulator
CP971_RS28315	COG4585	Histidine kinase
CP971_RS28320	COG0577	efflux transmembrane transporter activity
CP971_RS28320	COG1136	(ABC) transporter
CP971_RS28340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP971_RS28345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CP971_RS28350	COG1216	Glycosyl transferase, family 2
CP971_RS28355	COG1984	allophanate hydrolase subunit 2
CP971_RS28365	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CP971_RS28385	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CP971_RS28430	COG0577	efflux transmembrane transporter activity
CP971_RS28430	COG1136	(ABC) transporter
CP971_RS28445	COG1285	pathogenesis
CP971_RS28450	COG3619	membrane
CP971_RS28465	COG1136	(ABC) transporter
CP971_RS28475	COG0494	nUDIX hydrolase
CP971_RS28495	COG4195	phage-related replication protein
CP971_RS28510	COG0564	pseudouridine synthase activity
CP971_RS28525	COG3424	synthase
CP971_RS28535	COG4221	oxidoreductase activity
CP971_RS28540	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CP971_RS28560	COG0477	Major facilitator Superfamily
CP971_RS28575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP971_RS28610	COG3201	nicotinamide mononucleotide transporter
CP971_RS28615	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP971_RS28615	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP971_RS28620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CP971_RS28625	COG0140	phosphoribosyl-ATP diphosphatase activity
CP971_RS28630	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CP971_RS28665	COG1960	acyl-CoA dehydrogenase activity
CP971_RS28675	COG1522	sequence-specific DNA binding
CP971_RS28680	COG1228	amidohydrolase
CP971_RS28725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP971_RS28730	COG0494	nUDIX hydrolase
CP971_RS28770	COG0330	HflC and HflK could
CP971_RS28785	COG3226	Transcriptional regulator
CP971_RS28795	COG0277	FAD linked oxidase domain protein
CP971_RS28795	COG0247	lactate metabolic process
CP971_RS28800	COG1216	Glycosyl transferase, family 2
CP971_RS28810	COG1113	amino acid transport
CP971_RS28815	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CP971_RS28845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP971_RS28870	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP971_RS28880	COG0726	polysaccharide deacetylase
CP971_RS28910	COG1902	pentaerythritol trinitrate reductase activity
CP971_RS28920	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP971_RS28940	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CP971_RS28945	COG1309	transcriptional regulator
CP971_RS28950	COG3842	ATPase activity
CP971_RS28955	COG1511	domain protein
CP971_RS28970	COG2205	protein histidine kinase activity
CP971_RS28970	COG3437	response regulator, receiver
CP971_RS28970	COG3850	Histidine kinase
CP971_RS28970	COG4999	Histidine kinase
CP971_RS28980	COG1191	sigma factor activity
CP971_RS29035	COG3751	2OG-Fe(II) oxygenase superfamily
CP971_RS29090	COG1278	Cold shock
CP971_RS29125	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CP971_RS29160	COG2318	DinB family
CP971_RS29240	COG0395	ABC-type sugar transport system, permease component
CP971_RS29245	COG1175	transmembrane transport
CP971_RS29255	COG1609	Transcriptional regulator
CP971_RS29305	COG2124	cytochrome p450
CP971_RS29335	COG1233	COG1233 Phytoene dehydrogenase and related
CP971_RS29345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP971_RS29350	COG2353	YceI-like domain
CP971_RS29405	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP971_RS29425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP971_RS29430	COG0165	Argininosuccinate lyase
CP971_RS29440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP971_RS29445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP971_RS29470	COG0644	oxidoreductase
CP971_RS29495	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP971_RS29510	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CP971_RS29560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP971_RS29605	COG0137	argininosuccinate synthase activity
CP971_RS29655	COG0367	asparagine synthase
CP971_RS29665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP971_RS29675	COG1131	(ABC) transporter
CP971_RS29680	COG0842	Transport permease protein
CP971_RS29685	COG1834	amidinotransferase
CP971_RS29695	COG1960	acyl-CoA dehydrogenase activity
CP971_RS29720	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CP971_RS29725	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CP971_RS29735	COG4221	oxidoreductase activity
CP971_RS29745	COG1278	Cold shock
CP971_RS29750	COG0513	Belongs to the DEAD box helicase family
CP971_RS29760	COG2353	YceI-like domain
CP971_RS29765	COG3290	protein histidine kinase activity
CP971_RS29770	COG0697	spore germination
CP971_RS29805	COG1960	acyl-CoA dehydrogenase activity
CP971_RS29810	COG2124	cytochrome p450
CP971_RS29850	COG2226	methyltransferase
CP971_RS29850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP971_RS29850	COG3433	isochorismatase activity
CP971_RS29855	COG1022	Amp-dependent synthetase and ligase
CP971_RS29910	COG0395	ABC-type sugar transport system, permease component
CP971_RS29915	COG1175	transmembrane transport
CP971_RS29920	COG2182	Extracellular solute-binding protein
CP971_RS29950	COG2267	carboxylic ester hydrolase activity
CP971_RS29955	COG0783	Belongs to the Dps family
CP971_RS29965	COG2259	Doxx family
CP971_RS29970	COG1335	isochorismatase
CP971_RS29990	COG3619	membrane
CP971_RS30015	COG1819	glycosyl
CP971_RS30035	COG0604	alcohol dehydrogenase
CP971_RS30035	COG3321	synthase
CP971_RS30050	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CP971_RS30080	COG0745	RESPONSE REGULATOR receiver
CP971_RS30085	COG5002	protein histidine kinase activity
CP971_RS30115	COG0681	Belongs to the peptidase S26 family
CP971_RS30175	COG1335	isochorismatase
CP971_RS30180	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS30190	COG3387	PFAM Glycoside hydrolase 15-related
CP971_RS30215	COG2188	Transcriptional regulator
CP971_RS30220	COG1940	carbohydrate kinase activity
CP971_RS30230	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP971_RS30250	COG0745	RESPONSE REGULATOR receiver
CP971_RS30255	COG2205	protein histidine kinase activity
CP971_RS30260	COG2264	protein methyltransferase activity
CP971_RS30265	COG0006	proline dipeptidase activity
CP971_RS30275	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CP971_RS30280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP971_RS30285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CP971_RS30315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP971_RS30325	COG1793	dna ligase
CP971_RS30335	COG1063	alcohol dehydrogenase
CP971_RS30340	COG0156	8-amino-7-oxononanoate synthase activity
CP971_RS30345	COG1073	alpha beta
CP971_RS30355	COG0583	DNA-binding transcription factor activity
CP971_RS30365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP971_RS30380	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP971_RS30390	COG2226	methyltransferase
CP971_RS30405	COG4585	Histidine kinase
CP971_RS30410	COG2197	response regulator
CP971_RS30420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP971_RS30445	COG0318	PFAM AMP-dependent synthetase and ligase
CP971_RS30460	COG0477	Major facilitator Superfamily
CP971_RS30470	COG1799	cell septum assembly
CP971_RS30475	COG2318	DinB family
CP971_RS30490	COG2197	response regulator
CP971_RS30500	COG0738	Major facilitator superfamily
CP971_RS30520	COG0584	glycerophosphoryl diester phosphodiesterase
CP971_RS30535	COG4257	antibiotic catabolic process
CP971_RS30540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP971_RS30595	COG1686	Belongs to the peptidase S11 family
CP971_RS30620	COG2267	carboxylic ester hydrolase activity
CP971_RS30625	COG2197	response regulator
CP971_RS30630	COG4585	Histidine kinase
CP971_RS30635	COG2409	Drug exporters of the RND superfamily
CP971_RS30670	COG1064	alcohol dehydrogenase
CP971_RS30705	COG1309	transcriptional regulator
CP971_RS30720	COG4122	O-methyltransferase activity
CP971_RS30740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP971_RS30815	COG0189	ligase activity
CP971_RS30830	COG1733	regulation of RNA biosynthetic process
CP971_RS30850	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS30875	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP971_RS30890	COG2755	lipolytic protein G-D-S-L family
CP971_RS30890	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CP971_RS30910	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP971_RS30920	COG0667	Aldo Keto reductase
CP971_RS30935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP971_RS30955	COG1119	ATPase activity
CP971_RS30965	COG2837	iron assimilation
CP971_RS30970	COG0672	)-iron permease
CP971_RS30980	COG0577	efflux transmembrane transporter activity
CP971_RS30985	COG1136	(ABC) transporter
CP971_RS31010	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP971_RS31015	COG1053	succinate dehydrogenase
CP971_RS31030	COG0386	Belongs to the glutathione peroxidase family
CP971_RS31035	COG3960	tartronate-semialdehyde synthase activity
CP971_RS31050	COG1309	transcriptional regulator
CP971_RS31055	COG0477	Major facilitator Superfamily
CP971_RS31060	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS31070	COG1175	transmembrane transport
CP971_RS31075	COG0395	ABC-type sugar transport system, permease component
CP971_RS31080	COG1653	transport
CP971_RS31105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP971_RS31145	COG2814	Major facilitator Superfamily
CP971_RS31180	COG1793	dna ligase
CP971_RS31205	COG2270	Major facilitator Superfamily
CP971_RS31220	COG2340	Cysteine-rich secretory protein family
CP971_RS31265	COG0726	polysaccharide deacetylase
CP971_RS31270	COG3012	SEC-C Motif Domain Protein
CP971_RS31290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP971_RS31365	COG1335	isochorismatase
CP971_RS31370	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CP971_RS31390	COG0477	Major facilitator Superfamily
CP971_RS31395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP971_RS31405	COG2267	carboxylic ester hydrolase activity
CP971_RS31470	COG1136	(ABC) transporter
CP971_RS31470	COG4591	ABC-type transport system involved in lipoprotein release permease component
CP971_RS31485	COG1136	(ABC) transporter
CP971_RS31580	COG0534	Mate efflux family protein
CP971_RS31650	COG0477	Major facilitator Superfamily
CP971_RS31655	COG0745	RESPONSE REGULATOR receiver
CP971_RS31660	COG2205	protein histidine kinase activity
CP971_RS31680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP971_RS31685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP971_RS31695	COG1104	cysteine desulfurase activity
CP971_RS31700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP971_RS31715	COG0531	amino acid
CP971_RS31765	COG3290	protein histidine kinase activity
CP971_RS31780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP971_RS31815	COG4221	oxidoreductase activity
CP971_RS31830	COG1595	DNA-templated transcription, initiation
CP971_RS31835	COG0671	phosphoesterase, PA-phosphatase related
CP971_RS31885	COG4948	Mandelate Racemase Muconate Lactonizing
CP971_RS31890	COG0375	protein maturation
CP971_RS31895	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP971_RS31900	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CP971_RS31905	COG0298	carbon dioxide binding
CP971_RS31910	COG0409	Hydrogenase expression formation protein
CP971_RS31930	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CP971_RS31950	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CP971_RS31960	COG3345	alpha-galactosidase
CP971_RS31970	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP971_RS31975	COG1349	DNA-binding transcription factor activity
CP971_RS31980	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP971_RS31985	COG1129	ABC transporter
CP971_RS32000	COG1309	transcriptional regulator
CP971_RS32010	COG0326	Molecular chaperone. Has ATPase activity
CP971_RS32030	COG0784	Response regulator, receiver
CP971_RS32030	COG2205	protein histidine kinase activity
CP971_RS32030	COG5002	protein histidine kinase activity
CP971_RS32035	COG1191	sigma factor activity
CP971_RS32050	COG2171	N-acyltransferase activity
CP971_RS32060	COG0318	PFAM AMP-dependent synthetase and ligase
CP971_RS32095	COG2271	Major facilitator Superfamily
CP971_RS32115	COG0702	epimerase
CP971_RS32145	COG0069	glutamate synthase activity
CP971_RS32165	COG3237	CsbD-like
CP971_RS32305	COG2890	protein-(glutamine-N5) methyltransferase activity
CP971_RS32310	COG0589	response to stress
CP971_RS32320	COG1228	amidohydrolase
CP971_RS32330	COG2814	Major facilitator Superfamily
CP971_RS32335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP971_RS32335	COG1263	PTS System
CP971_RS32380	COG4221	oxidoreductase activity
CP971_RS32395	COG0640	Transcriptional regulator
CP971_RS32415	COG0583	DNA-binding transcription factor activity
CP971_RS32440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CP971_RS32455	COG4213	ABC transporter substrate-binding protein
CP971_RS32465	COG4214	carbohydrate transport
CP971_RS32475	COG1309	transcriptional regulator
CP971_RS32480	COG1063	alcohol dehydrogenase
CP971_RS32490	COG3835	regulator
CP971_RS32520	COG0542	response to heat
CP971_RS32535	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP971_RS32540	COG0443	Heat shock 70 kDa protein
CP971_RS32560	COG0515	serine threonine protein kinase
CP971_RS32560	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP971_RS32575	COG0714	Associated with various cellular activities
CP971_RS32620	COG3321	synthase
CP971_RS32620	COG0604	alcohol dehydrogenase
CP971_RS32620	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS32625	COG0667	Aldo Keto reductase
CP971_RS32705	COG0589	response to stress
CP971_RS32765	COG2801	Transposase and inactivated derivatives
CP971_RS32810	COG1592	Rubrerythrin
CP971_RS32840	COG0745	RESPONSE REGULATOR receiver
CP971_RS32845	COG0243	molybdopterin cofactor binding
CP971_RS32850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP971_RS32855	COG2146	nitrite reductase [NAD(P)H] activity
CP971_RS32855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP971_RS32860	COG2146	nitrite reductase [NAD(P)H] activity
CP971_RS32860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP971_RS32965	COG4232	protein-disulfide reductase activity
CP971_RS33035	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP971_RS33040	COG1129	ABC transporter
CP971_RS33050	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS33055	COG2186	Transcriptional regulator
CP971_RS33060	COG4948	Mandelate Racemase Muconate Lactonizing
CP971_RS33070	COG0800	Aldolase
CP971_RS33080	COG3386	PFAM SMP-30 Gluconolaconase
CP971_RS33165	COG1764	response to oxidative stress
CP971_RS33175	COG2197	response regulator
CP971_RS33200	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CP971_RS33215	COG2909	trisaccharide binding
CP971_RS33225	COG1073	alpha beta
CP971_RS33235	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS33380	COG1028	Short-chain dehydrogenase reductase Sdr
CP971_RS33380	COG3321	synthase
CP971_RS33380	COG0604	alcohol dehydrogenase
CP971_RS33550	COG1902	pentaerythritol trinitrate reductase activity
CP971_RS33555	COG1846	Transcriptional regulator
CP971_RS33605	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP971_RS33610	COG2814	Major facilitator Superfamily
CP971_RS33615	COG3629	intracellular signal transduction
CP971_RS33620	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP971_RS33640	COG2175	clavaminate synthase activity
CP971_RS33645	COG0010	Belongs to the arginase family
CP971_RS33650	COG0367	asparagine synthase
CP971_RS33660	COG0667	Aldo Keto reductase
CP971_RS33670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP971_RS33690	COG2318	DinB family
CP971_RS33710	COG2801	Transposase and inactivated derivatives
CP971_RS33805	COG1231	oxidoreductase activity
CP971_RS33835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP971_RS33970	COG0456	acetyltransferase
CP971_RS33970	COG0454	-acetyltransferase
CP971_RS33985	COG2814	Major facilitator Superfamily
CP971_RS34060	COG1846	Transcriptional regulator
CP971_RS34120	COG3293	Transposase
CP971_RS34125	COG3547	Transposase (IS116 IS110 IS902 family)
CP971_RS34150	COG1484	DNA-dependent DNA replication
CP971_RS34205	COG4974	Belongs to the 'phage' integrase family
CP971_RS34215	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP971_RS34285	COG2801	Transposase and inactivated derivatives
CP971_RS34300	COG2801	Transposase and inactivated derivatives
CP971_RS34355	COG3655	Transcriptional regulator
CP971_RS34410	COG2801	Transposase and inactivated derivatives