locus-tag	class	description
CP969_RS00225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP969_RS00440	COG3387	PFAM Glycoside hydrolase 15-related
CP969_RS00500	COG3971	2-oxopent-4-enoate hydratase activity
CP969_RS00505	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CP969_RS00515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP969_RS00585	COG2963	transposase activity
CP969_RS00595	COG2801	Transposase and inactivated derivatives
CP969_RS00630	COG0583	DNA-binding transcription factor activity
CP969_RS00635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP969_RS00645	COG0402	S-adenosylhomocysteine deaminase activity
CP969_RS00695	COG2267	carboxylic ester hydrolase activity
CP969_RS00745	COG0640	Transcriptional regulator
CP969_RS00750	COG0640	Transcriptional regulator
CP969_RS00755	COG2072	flavoprotein involved in K transport
CP969_RS00770	COG3118	belongs to the thioredoxin family
CP969_RS00775	COG0492	ferredoxin-NADP+ reductase activity
CP969_RS00780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP969_RS00790	COG0798	PFAM Bile acid sodium symporter
CP969_RS00835	COG0582	viral genome integration into host DNA
CP969_RS00905	COG1131	(ABC) transporter
CP969_RS00935	COG2066	Belongs to the glutaminase family
CP969_RS00975	COG2031	fatty acid transporter
CP969_RS00990	COG4249	Peptidase C14 caspase catalytic subunit p20
CP969_RS00990	COG2319	Wd-40 repeat
CP969_RS01000	COG2801	Transposase and inactivated derivatives
CP969_RS01005	COG3344	reverse transcriptase
CP969_RS01025	COG0202	RNA polymerase activity
CP969_RS01085	COG2409	Drug exporters of the RND superfamily
CP969_RS01095	COG0156	8-amino-7-oxononanoate synthase activity
CP969_RS01215	COG1309	transcriptional regulator
CP969_RS01220	COG0454	-acetyltransferase
CP969_RS01220	COG0456	acetyltransferase
CP969_RS01225	COG4638	Rieske (2fe-2S)
CP969_RS01230	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS01235	COG2814	Major facilitator Superfamily
CP969_RS01245	COG0183	Belongs to the thiolase family
CP969_RS01260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP969_RS01265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP969_RS01275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP969_RS01280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP969_RS01290	COG0183	Belongs to the thiolase family
CP969_RS01295	COG1024	Enoyl-CoA hydratase
CP969_RS01310	COG1960	acyl-CoA dehydrogenase activity
CP969_RS01380	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP969_RS01420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP969_RS01490	COG2304	oxidoreductase activity
CP969_RS01515	COG0596	Alpha beta hydrolase
CP969_RS01535	COG0076	glutamate decarboxylase activity
CP969_RS01615	COG1597	lipid kinase activity
CP969_RS01675	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CP969_RS01675	COG2070	2-Nitropropane dioxygenase
CP969_RS01685	COG3321	synthase
CP969_RS01685	COG0604	alcohol dehydrogenase
CP969_RS01730	COG1063	alcohol dehydrogenase
CP969_RS01735	COG2197	response regulator
CP969_RS01770	COG2197	response regulator
CP969_RS01775	COG1136	(ABC) transporter
CP969_RS01775	COG0577	efflux transmembrane transporter activity
CP969_RS01855	COG2801	Transposase and inactivated derivatives
CP969_RS01895	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP969_RS01915	COG1032	radical SAM domain protein
CP969_RS01950	COG3629	intracellular signal transduction
CP969_RS01950	COG3903	Transcriptional regulator
CP969_RS01995	COG1131	(ABC) transporter
CP969_RS02045	COG0745	RESPONSE REGULATOR receiver
CP969_RS02050	COG2205	protein histidine kinase activity
CP969_RS02115	COG2814	Major facilitator Superfamily
CP969_RS02130	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CP969_RS02135	COG4638	Rieske (2fe-2S)
CP969_RS02140	COG0583	DNA-binding transcription factor activity
CP969_RS02145	COG4948	Mandelate Racemase Muconate Lactonizing
CP969_RS02150	COG3485	protocatechuate 3,4-dioxygenase
CP969_RS02155	COG4829	muconolactone delta-isomerase
CP969_RS02170	COG0183	Belongs to the thiolase family
CP969_RS02215	COG3384	dioxygenase
CP969_RS02245	COG0477	Major facilitator Superfamily
CP969_RS02255	COG2267	carboxylic ester hydrolase activity
CP969_RS02320	COG1136	(ABC) transporter
CP969_RS02405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP969_RS02405	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP969_RS02425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP969_RS02425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP969_RS02440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP969_RS02445	COG1937	Protein conserved in bacteria
CP969_RS02485	COG1937	Protein conserved in bacteria
CP969_RS02510	COG0477	Major facilitator Superfamily
CP969_RS02535	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS02615	COG0437	4 iron, 4 sulfur cluster binding
CP969_RS02715	COG2197	response regulator
CP969_RS02720	COG4585	Histidine kinase
CP969_RS02770	COG1132	(ABC) transporter
CP969_RS02775	COG1132	(ABC) transporter
CP969_RS02800	COG1120	ATPase activity
CP969_RS02805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP969_RS02810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP969_RS02845	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS02850	COG1802	Transcriptional regulator
CP969_RS02855	COG4948	Mandelate Racemase Muconate Lactonizing
CP969_RS02875	COG3507	Belongs to the glycosyl hydrolase 43 family
CP969_RS02895	COG0395	ABC-type sugar transport system, permease component
CP969_RS02900	COG1175	transmembrane transport
CP969_RS02905	COG2182	Extracellular solute-binding protein
CP969_RS02935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP969_RS02940	COG1024	Enoyl-CoA hydratase
CP969_RS02950	COG0789	Transcriptional regulator
CP969_RS02955	COG1819	glycosyl
CP969_RS02965	COG1132	(ABC) transporter
CP969_RS02985	COG1024	Enoyl-CoA hydratase
CP969_RS02990	COG1024	Enoyl-CoA hydratase
CP969_RS03000	COG1834	amidinotransferase
CP969_RS03020	COG2255	four-way junction helicase activity
CP969_RS03025	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CP969_RS03050	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CP969_RS03065	COG0420	3'-5' exonuclease activity
CP969_RS03070	COG0419	ATPase involved in DNA repair
CP969_RS03115	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP969_RS03145	COG2197	response regulator
CP969_RS03180	COG1231	oxidoreductase activity
CP969_RS03195	COG2814	Major facilitator Superfamily
CP969_RS03200	COG2409	Drug exporters of the RND superfamily
CP969_RS03215	COG0831	urea catabolic process
CP969_RS03220	COG0832	Belongs to the urease beta subunit family
CP969_RS03225	COG0804	urea catabolic process
CP969_RS03230	COG0830	nickel cation binding
CP969_RS03235	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP969_RS03240	COG0829	nickel cation binding
CP969_RS03265	COG1649	PFAM Uncharacterised BCR, COG1649
CP969_RS03305	COG0277	FAD linked oxidase domain protein
CP969_RS03305	COG0247	lactate metabolic process
CP969_RS03380	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CP969_RS03415	COG2226	methyltransferase
CP969_RS03420	COG1132	(ABC) transporter
CP969_RS03440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CP969_RS03480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP969_RS03505	COG0604	alcohol dehydrogenase
CP969_RS03515	COG2815	serine threonine protein kinase
CP969_RS03515	COG0515	serine threonine protein kinase
CP969_RS03520	COG0006	proline dipeptidase activity
CP969_RS03535	COG2259	Doxx family
CP969_RS03540	COG2239	Acts as a magnesium transporter
CP969_RS03550	COG0596	Alpha beta hydrolase
CP969_RS03575	COG1294	oxidase, subunit
CP969_RS03580	COG1271	oxidase subunit
CP969_RS03595	COG2814	Major facilitator Superfamily
CP969_RS03600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CP969_RS03605	COG3386	PFAM SMP-30 Gluconolaconase
CP969_RS03630	COG2197	response regulator
CP969_RS03635	COG4585	Histidine kinase
CP969_RS03645	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CP969_RS03655	COG0277	FAD linked oxidase domain protein
CP969_RS03665	COG1960	acyl-CoA dehydrogenase activity
CP969_RS03670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP969_RS03680	COG0367	asparagine synthase
CP969_RS03690	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS03690	COG3321	synthase
CP969_RS03690	COG0300	oxidoreductase activity
CP969_RS03690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP969_RS03690	COG0318	PFAM AMP-dependent synthetase and ligase
CP969_RS03725	COG0673	inositol 2-dehydrogenase activity
CP969_RS03730	COG0561	phosphatase activity
CP969_RS03735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CP969_RS03740	COG1216	Glycosyl transferase, family 2
CP969_RS03745	COG0534	Mate efflux family protein
CP969_RS03755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP969_RS03760	COG2192	nodulation
CP969_RS03775	COG2192	nodulation
CP969_RS03790	COG1132	(ABC) transporter
CP969_RS03795	COG1132	(ABC) transporter
CP969_RS03800	COG0463	Glycosyl transferase, family 2
CP969_RS03835	COG0583	DNA-binding transcription factor activity
CP969_RS03880	COG0667	Aldo Keto reductase
CP969_RS03910	COG2045	Belongs to the ComB family
CP969_RS03915	COG1619	proteins homologs of microcin C7 resistance protein MccF
CP969_RS03935	COG0531	amino acid
CP969_RS03965	COG0318	PFAM AMP-dependent synthetase and ligase
CP969_RS03975	COG0183	Belongs to the thiolase family
CP969_RS03980	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS03990	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CP969_RS03995	COG1937	Protein conserved in bacteria
CP969_RS04000	COG0730	response to heat
CP969_RS04010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP969_RS04010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP969_RS04090	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS04110	COG2124	cytochrome p450
CP969_RS04120	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS04125	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS04130	COG1960	acyl-CoA dehydrogenase activity
CP969_RS04140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP969_RS04185	COG0318	PFAM AMP-dependent synthetase and ligase
CP969_RS04190	COG1960	acyl-CoA dehydrogenase activity
CP969_RS04195	COG2186	Transcriptional regulator
CP969_RS04200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP969_RS04205	COG1024	Enoyl-CoA hydratase
CP969_RS04230	COG0183	Belongs to the thiolase family
CP969_RS04235	COG1024	Enoyl-CoA hydratase
CP969_RS04245	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CP969_RS04265	COG1703	isobutyryl-CoA mutase activity
CP969_RS04265	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP969_RS04265	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP969_RS04270	COG0300	oxidoreductase activity
CP969_RS04290	COG0531	amino acid
CP969_RS04320	COG0583	DNA-binding transcription factor activity
CP969_RS04325	COG4977	sequence-specific DNA binding
CP969_RS04385	COG2318	DinB family
CP969_RS04415	COG0395	ABC-type sugar transport system, permease component
CP969_RS04435	COG0596	Alpha beta hydrolase
CP969_RS04445	COG2226	methyltransferase
CP969_RS04455	COG0640	Transcriptional regulator
CP969_RS04460	COG0346	lactoylglutathione lyase activity
CP969_RS04465	COG0076	glutamate decarboxylase activity
CP969_RS04475	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS04505	COG0438	transferase activity, transferring glycosyl groups
CP969_RS04515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP969_RS04520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP969_RS04570	COG0714	Associated with various cellular activities
CP969_RS04590	COG3896	Chloramphenicol phosphotransferase-like protein
CP969_RS04615	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CP969_RS04630	COG2353	YceI-like domain
CP969_RS04675	COG1024	Enoyl-CoA hydratase
CP969_RS04695	COG0515	serine threonine protein kinase
CP969_RS04705	COG1132	(ABC) transporter
CP969_RS04710	COG1132	(ABC) transporter
CP969_RS04715	COG2197	response regulator
CP969_RS04755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP969_RS04755	COG1024	Enoyl-CoA hydratase
CP969_RS04765	COG0375	protein maturation
CP969_RS04770	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP969_RS04775	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CP969_RS04785	COG0409	Hydrogenase expression formation protein
CP969_RS04800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP969_RS04870	COG1597	lipid kinase activity
CP969_RS04875	COG0277	FAD linked oxidase domain protein
CP969_RS04895	COG1082	Xylose isomerase domain protein TIM barrel
CP969_RS04925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP969_RS04935	COG0438	transferase activity, transferring glycosyl groups
CP969_RS04965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CP969_RS05025	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CP969_RS05040	COG0142	geranyltranstransferase activity
CP969_RS05060	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS05140	COG0456	acetyltransferase
CP969_RS05145	COG1295	ribonuclease BN
CP969_RS05175	COG0659	secondary active sulfate transmembrane transporter activity
CP969_RS05185	COG1063	alcohol dehydrogenase
CP969_RS05220	COG2124	cytochrome p450
CP969_RS05235	COG2192	nodulation
CP969_RS05245	COG0438	transferase activity, transferring glycosyl groups
CP969_RS05250	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CP969_RS05255	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CP969_RS05255	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CP969_RS05285	COG0753	catalase activity
CP969_RS05300	COG0009	L-threonylcarbamoyladenylate synthase
CP969_RS05310	COG0656	L-ascorbic acid biosynthetic process
CP969_RS05365	COG0366	Alpha amylase catalytic
CP969_RS05380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CP969_RS05385	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP969_RS05410	COG0784	Response regulator, receiver
CP969_RS05410	COG2205	protein histidine kinase activity
CP969_RS05410	COG5002	protein histidine kinase activity
CP969_RS05425	COG1366	Belongs to the anti-sigma-factor antagonist family
CP969_RS05430	COG1366	Belongs to the anti-sigma-factor antagonist family
CP969_RS05435	COG2172	sigma factor antagonist activity
CP969_RS05490	COG1982	Orn Lys Arg decarboxylase major
CP969_RS05500	COG0477	Major facilitator Superfamily
CP969_RS05510	COG0583	DNA-binding transcription factor activity
CP969_RS05555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP969_RS05585	COG2340	Cysteine-rich secretory protein family
CP969_RS05605	COG0515	serine threonine protein kinase
CP969_RS05610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP969_RS05630	COG0667	Aldo Keto reductase
CP969_RS05635	COG0328	RNA-DNA hybrid ribonuclease activity
CP969_RS05655	COG0740	serine-type endopeptidase activity
CP969_RS05660	COG0740	serine-type endopeptidase activity
CP969_RS05670	COG1191	sigma factor activity
CP969_RS05695	COG0842	Transport permease protein
CP969_RS05695	COG1716	ATPase activity
CP969_RS05695	COG1131	(ABC) transporter
CP969_RS05705	COG0667	Aldo Keto reductase
CP969_RS05710	COG0583	DNA-binding transcription factor activity
CP969_RS05720	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP969_RS05725	COG0346	lactoylglutathione lyase activity
CP969_RS05740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP969_RS05750	COG0431	NADPH-dependent FMN reductase
CP969_RS05780	COG2409	Drug exporters of the RND superfamily
CP969_RS05785	COG1846	Transcriptional regulator
CP969_RS05880	COG0318	PFAM AMP-dependent synthetase and ligase
CP969_RS05885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP969_RS05895	COG0515	serine threonine protein kinase
CP969_RS05930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP969_RS05930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP969_RS05945	COG0435	Glutathione S-transferase
CP969_RS05970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP969_RS05980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP969_RS05980	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP969_RS05995	COG3795	YCII-related domain
CP969_RS06000	COG4941	Belongs to the sigma-70 factor family
CP969_RS06005	COG1132	(ABC) transporter
CP969_RS06010	COG0659	secondary active sulfate transmembrane transporter activity
CP969_RS06015	COG0789	Transcriptional regulator
CP969_RS06020	COG2376	Dihydroxyacetone kinase
CP969_RS06025	COG1461	Dihydroxyacetone kinase
CP969_RS06055	COG1902	pentaerythritol trinitrate reductase activity
CP969_RS06055	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP969_RS06070	COG2890	protein-(glutamine-N5) methyltransferase activity
CP969_RS06080	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP969_RS06095	COG3458	cephalosporin-C deacetylase activity
CP969_RS06100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP969_RS06105	COG1802	Transcriptional regulator
CP969_RS06130	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CP969_RS06135	COG1686	Belongs to the peptidase S11 family
CP969_RS06150	COG1653	transport
CP969_RS06155	COG1175	transmembrane transport
CP969_RS06160	COG0395	ABC-type sugar transport system, permease component
CP969_RS06210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP969_RS06215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP969_RS06220	COG2867	negative regulation of translational initiation
CP969_RS06230	COG0673	inositol 2-dehydrogenase activity
CP969_RS06240	COG3973	AAA domain
CP969_RS06260	COG0589	response to stress
CP969_RS06265	COG0154	amidase activity
CP969_RS06330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP969_RS06350	COG3251	PFAM MbtH domain protein
CP969_RS06360	COG3340	Belongs to the peptidase S51 family
CP969_RS06370	COG2197	response regulator
CP969_RS06395	COG2124	cytochrome p450
CP969_RS06415	COG3534	alpha-L-arabinofuranosidase
CP969_RS06420	COG0477	Major facilitator Superfamily
CP969_RS06450	COG1473	amidohydrolase
CP969_RS06465	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS06490	COG1215	transferase activity, transferring glycosyl groups
CP969_RS06525	COG1349	DNA-binding transcription factor activity
CP969_RS06555	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP969_RS06560	COG1940	carbohydrate kinase activity
CP969_RS06565	COG2813	Specifically methylates the guanine in position
CP969_RS06575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP969_RS06580	COG1349	DNA-binding transcription factor activity
CP969_RS06585	COG3387	PFAM Glycoside hydrolase 15-related
CP969_RS06645	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS06680	COG1660	Displays ATPase and GTPase activities
CP969_RS06700	COG3655	Transcriptional regulator
CP969_RS06720	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CP969_RS06740	COG0204	Acyl-transferase
CP969_RS06770	COG0584	glycerophosphoryl diester phosphodiesterase
CP969_RS06810	COG0671	phosphoesterase, PA-phosphatase related
CP969_RS06815	COG1309	transcriptional regulator
CP969_RS06840	COG0640	Transcriptional regulator
CP969_RS06845	COG1902	pentaerythritol trinitrate reductase activity
CP969_RS06860	COG1960	acyl-CoA dehydrogenase activity
CP969_RS06870	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP969_RS06885	COG2706	6-phosphogluconolactonase activity
CP969_RS06945	COG0589	response to stress
CP969_RS06960	COG2072	flavoprotein involved in K transport
CP969_RS06970	COG1132	(ABC) transporter
CP969_RS06980	COG1132	(ABC) transporter
CP969_RS06985	COG1132	(ABC) transporter
CP969_RS06995	COG0254	rRNA binding
CP969_RS07010	COG1946	Acyl-CoA thioesterase
CP969_RS07015	COG2018	Roadblock/LC7 domain
CP969_RS07070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP969_RS07115	COG1960	acyl-CoA dehydrogenase activity
CP969_RS07120	COG1960	acyl-CoA dehydrogenase activity
CP969_RS07140	COG0492	ferredoxin-NADP+ reductase activity
CP969_RS07145	COG1793	dna ligase
CP969_RS07155	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS07170	COG1960	acyl-CoA dehydrogenase activity
CP969_RS07180	COG0242	peptide deformylase activity
CP969_RS07190	COG3442	glutamine amidotransferase
CP969_RS07195	COG0205	6-phosphofructokinase activity
CP969_RS07210	COG2815	serine threonine protein kinase
CP969_RS07210	COG0515	serine threonine protein kinase
CP969_RS07220	COG3275	phosphorelay sensor kinase activity
CP969_RS07225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP969_RS07235	COG3279	Response regulator of the LytR AlgR family
CP969_RS07240	COG1522	sequence-specific DNA binding
CP969_RS07245	COG1834	amidinotransferase
CP969_RS07250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP969_RS07270	COG0204	Acyl-transferase
CP969_RS07280	COG0740	serine-type endopeptidase activity
CP969_RS07315	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CP969_RS07320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP969_RS07325	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CP969_RS07330	COG2226	methyltransferase
CP969_RS07345	COG1136	(ABC) transporter
CP969_RS07345	COG0577	efflux transmembrane transporter activity
CP969_RS07350	COG0456	acetyltransferase
CP969_RS07370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP969_RS07375	COG3663	DNA glycosylase
CP969_RS07390	COG4585	Histidine kinase
CP969_RS07395	COG2197	response regulator
CP969_RS07400	COG1940	carbohydrate kinase activity
CP969_RS07405	COG2188	Transcriptional regulator
CP969_RS07410	COG1595	DNA-templated transcription, initiation
CP969_RS07415	COG0596	Alpha beta hydrolase
CP969_RS07420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP969_RS07435	COG0626	cystathionine gamma-synthase activity
CP969_RS07450	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS07455	COG0419	ATPase involved in DNA repair
CP969_RS07460	COG0420	3'-5' exonuclease activity
CP969_RS07465	COG1739	Uncharacterized protein family UPF0029
CP969_RS07480	COG1832	CoA-binding protein
CP969_RS07490	COG0501	Belongs to the peptidase M48B family
CP969_RS07495	COG0640	Transcriptional regulator
CP969_RS07520	COG0110	maltose O-acetyltransferase activity
CP969_RS07530	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CP969_RS07570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP969_RS07590	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS07605	COG0183	Belongs to the thiolase family
CP969_RS07615	COG1968	undecaprenyl-diphosphatase activity
CP969_RS07625	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS07655	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CP969_RS07675	COG2318	DinB family
CP969_RS07690	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP969_RS07725	COG0723	plastoquinol--plastocyanin reductase activity
CP969_RS07740	COG0697	spore germination
CP969_RS07825	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP969_RS07825	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CP969_RS07835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CP969_RS07875	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CP969_RS07905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP969_RS07915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP969_RS07930	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CP969_RS07950	COG2018	Roadblock/LC7 domain
CP969_RS07965	COG1414	Transcriptional regulator
CP969_RS07990	COG2814	Major facilitator Superfamily
CP969_RS07995	COG4336	lyase activity
CP969_RS08000	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CP969_RS08005	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CP969_RS08010	COG1984	allophanate hydrolase subunit 2
CP969_RS08050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP969_RS08055	COG2364	Membrane
CP969_RS08065	COG2270	Major facilitator Superfamily
CP969_RS08080	COG1216	Glycosyl transferase, family 2
CP969_RS08105	COG1960	acyl-CoA dehydrogenase activity
CP969_RS08150	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CP969_RS08155	COG0140	phosphoribosyl-ATP diphosphatase activity
CP969_RS08160	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CP969_RS08165	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP969_RS08165	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP969_RS08170	COG3201	nicotinamide mononucleotide transporter
CP969_RS08180	COG0702	epimerase
CP969_RS08185	COG1940	carbohydrate kinase activity
CP969_RS08185	COG1846	Transcriptional regulator
CP969_RS08190	COG2223	nitrite transmembrane transporter activity
CP969_RS08200	COG2233	PERMEase
CP969_RS08220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP969_RS08255	COG0531	amino acid
CP969_RS08265	COG2390	Transcriptional regulator
CP969_RS08270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CP969_RS08275	COG2409	Drug exporters of the RND superfamily
CP969_RS08285	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CP969_RS08300	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CP969_RS08310	COG1758	RNA polymerase activity
CP969_RS08315	COG0194	GDP metabolic process
CP969_RS08325	COG0284	orotidine-5'-phosphate decarboxylase activity
CP969_RS08330	COG0167	dihydroorotate dehydrogenase activity
CP969_RS08335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CP969_RS08340	COG0505	Belongs to the CarA family
CP969_RS08350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP969_RS08355	COG0540	Belongs to the ATCase OTCase family
CP969_RS08360	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CP969_RS08370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CP969_RS08375	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CP969_RS08380	COG0006	proline dipeptidase activity
CP969_RS08390	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CP969_RS08395	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CP969_RS08400	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CP969_RS08405	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP969_RS08420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CP969_RS08425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CP969_RS08445	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CP969_RS08460	COG0124	histidyl-tRNA synthetase
CP969_RS08470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CP969_RS08475	COG1196	nuclear chromosome segregation
CP969_RS08480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP969_RS08490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CP969_RS08495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP969_RS08500	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP969_RS08510	COG2255	four-way junction helicase activity
CP969_RS08515	COG0632	four-way junction helicase activity
CP969_RS08520	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CP969_RS08525	COG0217	transcriptional regulatory protein
CP969_RS08530	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CP969_RS08535	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CP969_RS08545	COG0438	transferase activity, transferring glycosyl groups
CP969_RS08550	COG1560	Kdo2-lipid A biosynthetic process
CP969_RS08555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CP969_RS08575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CP969_RS08590	COG5002	protein histidine kinase activity
CP969_RS08590	COG2176	DNA-directed DNA polymerase activity
CP969_RS08615	COG0395	ABC-type sugar transport system, permease component
CP969_RS08620	COG1175	transmembrane transport
CP969_RS08670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CP969_RS08730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP969_RS08730	COG1648	precorrin-2 dehydrogenase activity
CP969_RS08735	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP969_RS08755	COG1464	Belongs to the NlpA lipoprotein family
CP969_RS08760	COG2011	ABC-type metal ion transport system permease component
CP969_RS08765	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CP969_RS08795	COG0584	glycerophosphoryl diester phosphodiesterase
CP969_RS08800	COG0318	PFAM AMP-dependent synthetase and ligase
CP969_RS08800	COG0204	Acyl-transferase
CP969_RS08805	COG0477	Major facilitator Superfamily
CP969_RS08820	COG0165	Argininosuccinate lyase
CP969_RS08825	COG0137	argininosuccinate synthase activity
CP969_RS08860	COG1438	arginine binding
CP969_RS08865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP969_RS08870	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CP969_RS08875	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CP969_RS08880	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CP969_RS08910	COG0697	spore germination
CP969_RS08920	COG1649	PFAM Uncharacterised BCR, COG1649
CP969_RS08945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP969_RS08945	COG0072	phenylalanine-tRNA ligase activity
CP969_RS08950	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CP969_RS08955	COG5002	protein histidine kinase activity
CP969_RS08960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CP969_RS08965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CP969_RS08970	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CP969_RS08975	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CP969_RS09015	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS09020	COG0174	glutamine synthetase
CP969_RS09030	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP969_RS09055	COG4176	ABC-type proline glycine betaine transport system permease component
CP969_RS09060	COG4175	Glycine betaine
CP969_RS09060	COG0517	IMP dehydrogenase activity
CP969_RS09065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP969_RS09120	COG0805	protein transport
CP969_RS09125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP969_RS09145	COG2378	regulation of single-species biofilm formation
CP969_RS09160	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP969_RS09170	COG1609	Transcriptional regulator
CP969_RS09175	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP969_RS09180	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CP969_RS09195	COG4122	O-methyltransferase activity
CP969_RS09200	COG1222	aaa ATPase
CP969_RS09225	COG0517	IMP dehydrogenase activity
CP969_RS09225	COG1994	Peptidase M50
CP969_RS09235	COG2197	response regulator
CP969_RS09240	COG4166	transmembrane transport
CP969_RS09250	COG1410	methionine synthase
CP969_RS09250	COG0646	methionine synthase
CP969_RS09255	COG1414	Transcriptional regulator
CP969_RS09260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CP969_RS09265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP969_RS09270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP969_RS09280	COG0215	cysteine-tRNA ligase activity
CP969_RS09295	COG0588	phosphoglycerate mutase activity
CP969_RS09300	COG0598	Magnesium transport protein CorA
CP969_RS09310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP969_RS09315	COG0667	Aldo Keto reductase
CP969_RS09345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP969_RS09355	COG3012	SEC-C Motif Domain Protein
CP969_RS09360	COG2186	Transcriptional regulator
CP969_RS09365	COG3265	gluconokinase activity
CP969_RS09375	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS09380	COG1063	alcohol dehydrogenase
CP969_RS09400	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP969_RS09405	COG2149	membrane
CP969_RS09425	COG1960	acyl-CoA dehydrogenase activity
CP969_RS09440	COG3876	Protein conserved in bacteria
CP969_RS09450	COG0789	Transcriptional regulator
CP969_RS09470	COG1960	acyl-CoA dehydrogenase activity
CP969_RS09480	COG0640	Transcriptional regulator
CP969_RS09505	COG2851	Citrate transporter
CP969_RS09510	COG0243	molybdopterin cofactor binding
CP969_RS09515	COG1309	transcriptional regulator
CP969_RS09525	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CP969_RS09530	COG2188	Transcriptional regulator
CP969_RS09550	COG1595	DNA-templated transcription, initiation
CP969_RS09560	COG2755	lipolytic protein G-D-S-L family
CP969_RS09570	COG1216	Glycosyl transferase, family 2
CP969_RS09575	COG0726	polysaccharide deacetylase
CP969_RS09585	COG1725	Transcriptional regulator
CP969_RS09630	COG0330	HflC and HflK could
CP969_RS09645	COG1799	cell septum assembly
CP969_RS09650	COG1960	acyl-CoA dehydrogenase activity
CP969_RS09655	COG0477	Major facilitator Superfamily
CP969_RS09665	COG0671	phosphoesterase, PA-phosphatase related
CP969_RS09710	COG1652	LysM domain
CP969_RS09725	COG1160	GTP binding
CP969_RS09735	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CP969_RS09750	COG0723	plastoquinol--plastocyanin reductase activity
CP969_RS09770	COG1056	cytidyltransferase-related domain
CP969_RS09770	COG1051	belongs to the nudix hydrolase family
CP969_RS09775	COG1187	pseudouridine synthase activity
CP969_RS09780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CP969_RS09785	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CP969_RS09800	COG0686	Belongs to the AlaDH PNT family
CP969_RS09810	COG0494	nUDIX hydrolase
CP969_RS09815	COG0504	CTP synthase activity
CP969_RS09820	COG3387	PFAM Glycoside hydrolase 15-related
CP969_RS09835	COG0497	DNA recombination
CP969_RS09840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CP969_RS09860	COG1120	ATPase activity
CP969_RS09865	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP969_RS09870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP969_RS09875	COG0647	UMP catabolic process
CP969_RS09910	COG2094	Belongs to the DNA glycosylase MPG family
CP969_RS09920	COG1881	PFAM PEBP family protein
CP969_RS09940	COG1119	ATPase activity
CP969_RS09955	COG2197	response regulator
CP969_RS09965	COG4221	oxidoreductase activity
CP969_RS09970	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CP969_RS09980	COG0842	Transport permease protein
CP969_RS09980	COG1716	ATPase activity
CP969_RS09980	COG1131	(ABC) transporter
CP969_RS09990	COG0560	Phosphoserine phosphatase
CP969_RS09990	COG3830	Belongs to the UPF0237 family
CP969_RS09995	COG0588	phosphoglycerate mutase activity
CP969_RS10015	COG2186	Transcriptional regulator
CP969_RS10030	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS10060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CP969_RS10080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CP969_RS10085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP969_RS10105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP969_RS10115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP969_RS10130	COG3387	PFAM Glycoside hydrolase 15-related
CP969_RS10145	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CP969_RS10150	COG1869	D-ribose catabolic process
CP969_RS10155	COG1129	ABC transporter
CP969_RS10165	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP969_RS10170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP969_RS10220	COG0488	(ABC) transporter
CP969_RS10240	COG0235	Class ii aldolase
CP969_RS10255	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CP969_RS10260	COG1492	cobalamin metabolic process
CP969_RS10280	COG1797	cobyrinic acid a,c-diamide synthase activity
CP969_RS10315	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CP969_RS10335	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CP969_RS10345	COG0456	acetyltransferase
CP969_RS10350	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP969_RS10355	COG1917	Cupin 2, conserved barrel domain protein
CP969_RS10360	COG5285	phytanoyl-CoA dioxygenase
CP969_RS10365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP969_RS10385	COG1414	Transcriptional regulator
CP969_RS10400	COG4585	Histidine kinase
CP969_RS10410	COG1595	DNA-templated transcription, initiation
CP969_RS10430	COG4677	pectinesterase activity
CP969_RS10435	COG3866	Pectate lyase
CP969_RS10440	COG2755	lipolytic protein G-D-S-L family
CP969_RS10450	COG3507	Belongs to the glycosyl hydrolase 43 family
CP969_RS10460	COG0673	inositol 2-dehydrogenase activity
CP969_RS10465	COG0395	ABC-type sugar transport system, permease component
CP969_RS10470	COG1175	transmembrane transport
CP969_RS10485	COG1802	Transcriptional regulator
CP969_RS10500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP969_RS10505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP969_RS10510	COG1349	DNA-binding transcription factor activity
CP969_RS10525	COG0395	ABC-type sugar transport system, permease component
CP969_RS10530	COG1063	alcohol dehydrogenase
CP969_RS10545	COG1802	Transcriptional regulator
CP969_RS10580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP969_RS10595	COG2171	N-acyltransferase activity
CP969_RS10600	COG3226	Transcriptional regulator
CP969_RS10605	COG2076	Multidrug Resistance protein
CP969_RS10610	COG2151	metal-sulfur cluster biosynthetic enzyme
CP969_RS10615	COG0822	iron-sulfur transferase activity
CP969_RS10620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP969_RS10625	COG0396	ATPase activity
CP969_RS10635	COG0719	Fe-S assembly protein
CP969_RS10650	COG2746	aminoglycoside 3-N-acetyltransferase activity
CP969_RS10655	COG1131	(ABC) transporter
CP969_RS10665	COG1612	heme a metabolic process
CP969_RS10685	COG0109	protoheme IX farnesyltransferase activity
CP969_RS10700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CP969_RS10715	COG0363	glucosamine-6-phosphate deaminase activity
CP969_RS10720	COG0395	ABC-type sugar transport system, permease component
CP969_RS10725	COG1175	transmembrane transport
CP969_RS10730	COG1653	transport
CP969_RS10735	COG0366	Alpha amylase catalytic
CP969_RS10740	COG1653	transport
CP969_RS10745	COG1695	Transcriptional regulator
CP969_RS10750	COG1136	(ABC) transporter
CP969_RS10765	COG0166	Belongs to the GPI family
CP969_RS10775	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CP969_RS10780	COG0149	triose-phosphate isomerase activity
CP969_RS10785	COG0126	phosphoglycerate kinase activity
CP969_RS10790	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CP969_RS10800	COG1481	regulation of sporulation
CP969_RS10805	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP969_RS10810	COG1660	Displays ATPase and GTPase activities
CP969_RS10815	COG0322	excinuclease ABC activity
CP969_RS10835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP969_RS10840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP969_RS10855	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CP969_RS10860	COG0387	Pfam Sodium calcium exchanger
CP969_RS10880	COG0556	nucleotide-excision repair
CP969_RS10890	COG0584	glycerophosphoryl diester phosphodiesterase
CP969_RS10895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP969_RS10905	COG2313	pseudouridylate synthase activity
CP969_RS10910	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CP969_RS10910	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CP969_RS10980	COG0402	S-adenosylhomocysteine deaminase activity
CP969_RS11005	COG2267	carboxylic ester hydrolase activity
CP969_RS11020	COG2226	methyltransferase
CP969_RS11035	COG0237	dephospho-CoA kinase activity
CP969_RS11045	COG0539	negative regulation of cytoplasmic translation
CP969_RS11055	COG2226	methyltransferase
CP969_RS11060	COG1643	Atp-dependent helicase
CP969_RS11090	COG2050	protein possibly involved in aromatic compounds catabolism
CP969_RS11165	COG0745	RESPONSE REGULATOR receiver
CP969_RS11170	COG0287	Prephenate dehydrogenase
CP969_RS11170	COG1605	Chorismate mutase
CP969_RS11200	COG0067	glutamate synthase
CP969_RS11200	COG0069	glutamate synthase activity
CP969_RS11200	COG0070	glutamate synthase
CP969_RS11210	COG1397	ADP-ribosylglycohydrolase
CP969_RS11230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP969_RS11240	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CP969_RS11250	COG0159	tryptophan synthase activity
CP969_RS11255	COG0133	tryptophan synthase activity
CP969_RS11265	COG0134	indole-3-glycerol-phosphate synthase activity
CP969_RS11290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CP969_RS11305	COG0107	imidazoleglycerol-phosphate synthase activity
CP969_RS11310	COG0251	oxidation-reduction process
CP969_RS11315	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CP969_RS11320	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CP969_RS11325	COG0131	Imidazoleglycerol-phosphate dehydratase
CP969_RS11330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP969_RS11335	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CP969_RS11375	COG1432	Conserved Protein
CP969_RS11380	COG0587	DNA-directed DNA polymerase activity
CP969_RS11440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CP969_RS11455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CP969_RS11460	COG3599	regulation of cell shape
CP969_RS11470	COG1799	cell septum assembly
CP969_RS11480	COG1496	oxidoreductase activity
CP969_RS11485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CP969_RS11490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CP969_RS11495	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP969_RS11505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CP969_RS11510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP969_RS11520	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CP969_RS11535	COG0275	rRNA processing
CP969_RS11545	COG0714	Associated with various cellular activities
CP969_RS11575	COG1126	abc transporter atp-binding protein
CP969_RS11585	COG1309	transcriptional regulator
CP969_RS11605	COG0352	thiamine-phosphate diphosphorylase activity
CP969_RS11635	COG2022	thiamine diphosphate biosynthetic process
CP969_RS11640	COG2815	serine threonine protein kinase
CP969_RS11640	COG0515	serine threonine protein kinase
CP969_RS11645	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CP969_RS11650	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CP969_RS11655	COG2193	ferroxidase activity
CP969_RS11665	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CP969_RS11680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP969_RS11685	COG2197	response regulator
CP969_RS11715	COG1940	carbohydrate kinase activity
CP969_RS11725	COG0003	Pfam Anion-transporting ATPase
CP969_RS11795	COG2205	protein histidine kinase activity
CP969_RS11800	COG0745	RESPONSE REGULATOR receiver
CP969_RS11810	COG1929	Belongs to the glycerate kinase type-1 family
CP969_RS11815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CP969_RS11820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CP969_RS11825	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CP969_RS11830	COG0723	plastoquinol--plastocyanin reductase activity
CP969_RS11835	COG2010	Cytochrome c
CP969_RS11840	COG1845	cytochrome c oxidase, subunit III
CP969_RS11850	COG1376	ErfK ybiS ycfS ynhG family protein
CP969_RS11860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP969_RS11865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CP969_RS11875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP969_RS11900	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CP969_RS11905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CP969_RS11910	COG2197	response regulator
CP969_RS11915	COG4585	Histidine kinase
CP969_RS11935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CP969_RS11955	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CP969_RS11975	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CP969_RS11980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CP969_RS11985	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP969_RS11995	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP969_RS12045	COG0321	lipoyl(octanoyl) transferase activity
CP969_RS12050	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CP969_RS12070	COG0174	glutamine synthetase
CP969_RS12110	COG0745	RESPONSE REGULATOR receiver
CP969_RS12125	COG2197	response regulator
CP969_RS12145	COG1309	transcriptional regulator
CP969_RS12165	COG0366	Alpha amylase catalytic
CP969_RS12170	COG3833	ABC-type maltose transport systems, permease component
CP969_RS12175	COG1175	transmembrane transport
CP969_RS12180	COG1653	transport
CP969_RS12185	COG1609	Transcriptional regulator
CP969_RS12195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CP969_RS12215	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP969_RS12220	COG1309	transcriptional regulator
CP969_RS12275	COG0174	glutamine synthetase
CP969_RS12290	COG1959	2 iron, 2 sulfur cluster binding
CP969_RS12305	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CP969_RS12305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CP969_RS12320	COG0477	Major facilitator Superfamily
CP969_RS12325	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CP969_RS12350	COG1994	Peptidase M50
CP969_RS12390	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CP969_RS12395	COG0726	polysaccharide deacetylase
CP969_RS12400	COG0300	oxidoreductase activity
CP969_RS12430	COG0584	glycerophosphoryl diester phosphodiesterase
CP969_RS12450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP969_RS12455	COG2814	Major facilitator Superfamily
CP969_RS12465	COG3540	Alkaline phosphatase
CP969_RS12490	COG2259	Doxx family
CP969_RS12520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP969_RS12530	COG1201	RNA secondary structure unwinding
CP969_RS12615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP969_RS12620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP969_RS12630	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP969_RS12635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP969_RS12665	COG3022	response to hydroperoxide
CP969_RS12670	COG0800	Aldolase
CP969_RS12685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CP969_RS12695	COG2030	dehydratase
CP969_RS12705	COG0477	Major facilitator Superfamily
CP969_RS12740	COG0438	transferase activity, transferring glycosyl groups
CP969_RS12745	COG1309	transcriptional regulator
CP969_RS12755	COG1657	PFAM Prenyltransferase squalene oxidase
CP969_RS12770	COG3845	ABC transporter
CP969_RS12795	COG4122	O-methyltransferase activity
CP969_RS12850	COG2259	Doxx family
CP969_RS12900	COG0586	Pfam SNARE associated Golgi protein
CP969_RS12910	COG1358	cellular component organization or biogenesis
CP969_RS12955	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CP969_RS12965	COG0477	Major facilitator Superfamily
CP969_RS12970	COG1309	transcriptional regulator
CP969_RS12985	COG0789	Transcriptional regulator
CP969_RS13040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP969_RS13045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP969_RS13050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP969_RS13075	COG1280	lysine exporter protein (LysE YggA)
CP969_RS13085	COG2130	NADP-dependent
CP969_RS13115	COG4213	ABC transporter substrate-binding protein
CP969_RS13125	COG4214	carbohydrate transport
CP969_RS13135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP969_RS13170	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CP969_RS13195	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CP969_RS13230	COG3507	Belongs to the glycosyl hydrolase 43 family
CP969_RS13250	COG0395	ABC-type sugar transport system, permease component
CP969_RS13255	COG1175	transmembrane transport
CP969_RS13290	COG3386	PFAM SMP-30 Gluconolaconase
CP969_RS13295	COG1414	Transcriptional regulator
CP969_RS13410	COG0318	PFAM AMP-dependent synthetase and ligase
CP969_RS13415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CP969_RS13415	COG0825	malonyl-CoA metabolic process
CP969_RS13425	COG1077	Cell shape determining protein MreB Mrl
CP969_RS13465	COG1070	Carbohydrate kinase
CP969_RS13480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP969_RS13495	COG0358	DNA primase activity
CP969_RS13505	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CP969_RS13515	COG2949	membrane
CP969_RS13520	COG0243	molybdopterin cofactor binding
CP969_RS13530	COG0431	NADPH-dependent FMN reductase
CP969_RS13550	COG2146	nitrite reductase [NAD(P)H] activity
CP969_RS13550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP969_RS13555	COG2146	nitrite reductase [NAD(P)H] activity
CP969_RS13555	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CP969_RS13580	COG0574	Belongs to the PEP-utilizing enzyme family
CP969_RS13580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CP969_RS13590	COG0733	neurotransmitter:sodium symporter activity
CP969_RS13615	COG0423	glycine-tRNA ligase activity
CP969_RS13620	COG0803	Belongs to the bacterial solute-binding protein 9 family
CP969_RS13620	COG3443	Belongs to the bacterial solute-binding protein 9 family
CP969_RS13625	COG1121	(ABC) transporter
CP969_RS13630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CP969_RS13640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP969_RS13645	COG1381	Involved in DNA repair and RecF pathway recombination
CP969_RS13730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP969_RS13755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CP969_RS13765	COG2315	Protein conserved in bacteria
CP969_RS13775	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CP969_RS13790	COG4948	Mandelate Racemase Muconate Lactonizing
CP969_RS13800	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP969_RS13805	COG1234	tRNA 3'-trailer cleavage
CP969_RS13810	COG0537	adenosine 5'-monophosphoramidase activity
CP969_RS13815	COG0793	Belongs to the peptidase S41A family
CP969_RS13815	COG4946	Tricorn protease homolog
CP969_RS13840	COG0484	heat shock protein binding
CP969_RS13845	COG1420	regulation of RNA biosynthetic process
CP969_RS13875	COG0481	GTPase activity
CP969_RS13885	COG0268	Binds directly to 16S ribosomal RNA
CP969_RS13900	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CP969_RS13905	COG2353	YceI-like domain
CP969_RS13910	COG1234	tRNA 3'-trailer cleavage
CP969_RS13915	COG1555	photosystem II stabilization
CP969_RS13920	COG1307	EDD domain protein, DegV family
CP969_RS13930	COG0495	leucyl-tRNA aminoacylation
CP969_RS13945	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP969_RS13970	COG0588	phosphoglycerate mutase activity
CP969_RS13975	COG0799	negative regulation of ribosome biogenesis
CP969_RS13985	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CP969_RS13990	COG0501	Belongs to the peptidase M48B family
CP969_RS14005	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CP969_RS14015	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CP969_RS14030	COG1215	transferase activity, transferring glycosyl groups
CP969_RS14045	COG3540	Alkaline phosphatase
CP969_RS14050	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CP969_RS14055	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CP969_RS14060	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CP969_RS14090	COG1530	ribonuclease E activity
CP969_RS14135	COG0772	Belongs to the SEDS family
CP969_RS14140	COG0768	penicillin binding
CP969_RS14155	COG1077	Cell shape determining protein MreB Mrl
CP969_RS14160	COG0105	UTP biosynthetic process
CP969_RS14170	COG0285	dihydrofolate synthase activity
CP969_RS14175	COG0525	valine-tRNA ligase activity
CP969_RS14185	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CP969_RS14190	COG0740	serine-type endopeptidase activity
CP969_RS14195	COG0740	serine-type endopeptidase activity
CP969_RS14200	COG0544	peptidyl-prolyl cis-trans isomerase activity
CP969_RS14220	COG3594	Acyltransferase
CP969_RS14240	COG4552	Acetyltransferase involved in intracellular survival and related
CP969_RS14255	COG1113	amino acid transport
CP969_RS14275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CP969_RS14285	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CP969_RS14315	COG0346	lactoylglutathione lyase activity
CP969_RS14390	COG1309	transcriptional regulator
CP969_RS14400	COG0697	spore germination
CP969_RS14405	COG1846	Transcriptional regulator
CP969_RS14410	COG0778	Nitroreductase
CP969_RS14430	COG3291	Pkd domain containing protein
CP969_RS14430	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP969_RS14435	COG1595	DNA-templated transcription, initiation
CP969_RS14445	COG1131	(ABC) transporter
CP969_RS14465	COG0668	transmembrane transport
CP969_RS14475	COG1486	melibiose metabolic process
CP969_RS14630	COG0629	single-stranded DNA binding
CP969_RS14635	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CP969_RS14705	COG2304	oxidoreductase activity
CP969_RS14735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CP969_RS14745	COG0728	peptidoglycan biosynthetic process
CP969_RS14755	COG0438	transferase activity, transferring glycosyl groups
CP969_RS14775	COG0492	ferredoxin-NADP+ reductase activity
CP969_RS14790	COG1131	(ABC) transporter
CP969_RS14810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP969_RS14835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CP969_RS14855	COG0673	inositol 2-dehydrogenase activity
CP969_RS14885	COG1472	Belongs to the glycosyl hydrolase 3 family
CP969_RS14910	COG2356	endonuclease I
CP969_RS14935	COG0028	Belongs to the TPP enzyme family
CP969_RS14945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP969_RS14960	COG1946	Acyl-CoA thioesterase
CP969_RS14970	COG1309	transcriptional regulator
CP969_RS14975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP969_RS14990	COG1960	acyl-CoA dehydrogenase activity
CP969_RS15005	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CP969_RS15030	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP969_RS15035	COG0589	response to stress
CP969_RS15040	COG4977	sequence-specific DNA binding
CP969_RS15045	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CP969_RS15070	COG0395	ABC-type sugar transport system, permease component
CP969_RS15085	COG0745	RESPONSE REGULATOR receiver
CP969_RS15095	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CP969_RS15110	COG0406	alpha-ribazole phosphatase activity
CP969_RS15160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP969_RS15175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP969_RS15190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP969_RS15195	COG0765	amino acid transport
CP969_RS15200	COG0765	amino acid transport
CP969_RS15205	COG1126	abc transporter atp-binding protein
CP969_RS15220	COG3397	chitin binding
CP969_RS15250	COG4249	Peptidase C14 caspase catalytic subunit p20
CP969_RS15250	COG2319	Wd-40 repeat
CP969_RS15280	COG1940	carbohydrate kinase activity
CP969_RS15285	COG0673	inositol 2-dehydrogenase activity
CP969_RS15290	COG4702	Belongs to the UPF0303 family
CP969_RS15305	COG0706	membrane insertase activity
CP969_RS15325	COG1414	Transcriptional regulator
CP969_RS15400	COG1074	ATP-dependent DNA helicase activity
CP969_RS15450	COG3226	Transcriptional regulator
CP969_RS15490	COG2814	Major facilitator Superfamily
CP969_RS15495	COG2733	membrane
CP969_RS15510	COG4555	ABC transporter
CP969_RS15525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP969_RS15555	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CP969_RS15565	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CP969_RS15570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CP969_RS15575	COG1263	PTS System
CP969_RS15580	COG1263	PTS System
CP969_RS15585	COG1234	tRNA 3'-trailer cleavage
CP969_RS15615	COG1113	amino acid transport
CP969_RS15625	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CP969_RS15635	COG1335	isochorismatase
CP969_RS15665	COG0277	FAD linked oxidase domain protein
CP969_RS15675	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CP969_RS15685	COG1174	glycine betaine transport
CP969_RS15710	COG3654	unkown
CP969_RS15810	COG2186	Transcriptional regulator
CP969_RS15845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP969_RS15860	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CP969_RS15865	COG0395	ABC-type sugar transport system, permease component
CP969_RS15885	COG1678	Uncharacterized ACR, COG1678
CP969_RS15890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP969_RS15895	COG0776	regulation of translation
CP969_RS15905	COG3973	AAA domain
CP969_RS15930	COG2223	nitrite transmembrane transporter activity
CP969_RS15975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CP969_RS15980	COG0793	Belongs to the peptidase S41A family
CP969_RS15990	COG2884	Cell division ATP-binding protein ftsE
CP969_RS16005	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CP969_RS16010	COG0515	serine threonine protein kinase
CP969_RS16020	COG0515	serine threonine protein kinase
CP969_RS16035	COG1175	transmembrane transport
CP969_RS16040	COG0395	ABC-type sugar transport system, permease component
CP969_RS16045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP969_RS16050	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP969_RS16055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP969_RS16055	COG0463	Glycosyl transferase, family 2
CP969_RS16070	COG1764	response to oxidative stress
CP969_RS16075	COG1846	Transcriptional regulator
CP969_RS16080	COG1215	transferase activity, transferring glycosyl groups
CP969_RS16100	COG1134	teichoic acid transport
CP969_RS16105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CP969_RS16110	COG1215	transferase activity, transferring glycosyl groups
CP969_RS16120	COG2902	Dehydrogenase
CP969_RS16125	COG0546	phosphoglycolate phosphatase activity
CP969_RS16140	COG0653	protein targeting
CP969_RS16150	COG3214	Protein conserved in bacteria
CP969_RS16155	COG2197	response regulator
CP969_RS16160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CP969_RS16170	COG0823	Involved in the tonB-independent uptake of proteins
CP969_RS16175	COG5000	phosphorelay sensor kinase activity
CP969_RS16175	COG5002	protein histidine kinase activity
CP969_RS16180	COG0745	RESPONSE REGULATOR receiver
CP969_RS16185	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CP969_RS16205	COG0714	Associated with various cellular activities
CP969_RS16250	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CP969_RS16260	COG1482	cell wall glycoprotein biosynthetic process
CP969_RS16270	COG2835	tetraacyldisaccharide 4'-kinase activity
CP969_RS16275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP969_RS16280	COG1620	l-lactate permease
CP969_RS16320	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CP969_RS16325	COG0778	Nitroreductase
CP969_RS16325	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CP969_RS16350	COG1316	TRANSCRIPTIONal
CP969_RS16355	COG1316	TRANSCRIPTIONal
CP969_RS16360	COG1316	TRANSCRIPTIONal
CP969_RS16365	COG1316	TRANSCRIPTIONal
CP969_RS16375	COG1316	TRANSCRIPTIONal
CP969_RS16380	COG1607	acyl-coa hydrolase
CP969_RS16385	COG1316	TRANSCRIPTIONal
CP969_RS16395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CP969_RS16405	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP969_RS16445	COG2205	protein histidine kinase activity
CP969_RS16450	COG0745	RESPONSE REGULATOR receiver
CP969_RS16455	COG3104	oligopeptide transport
CP969_RS16465	COG1366	Belongs to the anti-sigma-factor antagonist family
CP969_RS16470	COG1191	sigma factor activity
CP969_RS16480	COG1228	amidohydrolase
CP969_RS16485	COG0402	S-adenosylhomocysteine deaminase activity
CP969_RS16495	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CP969_RS16530	COG2755	lipolytic protein G-D-S-L family
CP969_RS16535	COG0183	Belongs to the thiolase family
CP969_RS16575	COG1136	(ABC) transporter
CP969_RS16575	COG0577	efflux transmembrane transporter activity
CP969_RS16580	COG0577	efflux transmembrane transporter activity
CP969_RS16585	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CP969_RS16590	COG1252	NADH dehydrogenase
CP969_RS16620	COG0148	phosphopyruvate hydratase activity
CP969_RS16690	COG0577	efflux transmembrane transporter activity
CP969_RS16695	COG1136	(ABC) transporter
CP969_RS16700	COG0477	Major facilitator Superfamily
CP969_RS16710	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP969_RS16740	COG4585	Histidine kinase
CP969_RS16755	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CP969_RS16760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CP969_RS16765	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CP969_RS16770	COG0193	aminoacyl-tRNA hydrolase activity
CP969_RS16780	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CP969_RS16790	COG1309	transcriptional regulator
CP969_RS16800	COG4106	trans-aconitate 2-methyltransferase activity
CP969_RS16810	COG2197	response regulator
CP969_RS16820	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CP969_RS16850	COG0488	(ABC) transporter
CP969_RS16860	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CP969_RS16865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CP969_RS16870	COG0084	hydrolase, TatD family'
CP969_RS16915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CP969_RS16935	COG2409	Drug exporters of the RND superfamily
CP969_RS16945	COG4946	Tricorn protease homolog
CP969_RS16945	COG0793	Belongs to the peptidase S41A family
CP969_RS16955	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS16960	COG2267	carboxylic ester hydrolase activity
CP969_RS16965	COG2072	flavoprotein involved in K transport
CP969_RS16980	COG0708	Exodeoxyribonuclease III
CP969_RS17050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP969_RS17055	COG0521	Mo-molybdopterin cofactor biosynthetic process
CP969_RS17055	COG0315	cyclic pyranopterin monophosphate synthase activity
CP969_RS17060	COG0315	cyclic pyranopterin monophosphate synthase activity
CP969_RS17070	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CP969_RS17075	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CP969_RS17100	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CP969_RS17110	COG1970	mechanosensitive ion channel activity
CP969_RS17130	COG1376	ErfK ybiS ycfS ynhG family protein
CP969_RS17145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP969_RS17145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CP969_RS17145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP969_RS17155	COG1349	DNA-binding transcription factor activity
CP969_RS17170	COG3384	dioxygenase
CP969_RS17175	COG1846	Transcriptional regulator
CP969_RS17210	COG4974	Belongs to the 'phage' integrase family
CP969_RS17250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP969_RS17310	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CP969_RS17365	COG1278	Cold shock
CP969_RS17370	COG0513	Belongs to the DEAD box helicase family
CP969_RS17395	COG2207	Transcriptional regulator
CP969_RS17395	COG3708	Transcriptional regulator
CP969_RS17410	COG2132	Multicopper oxidase
CP969_RS17455	COG0569	domain protein
CP969_RS17460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CP969_RS17475	COG0386	Belongs to the glutathione peroxidase family
CP969_RS17500	COG1686	Belongs to the peptidase S11 family
CP969_RS17545	COG3629	intracellular signal transduction
CP969_RS17545	COG3903	Transcriptional regulator
CP969_RS17560	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP969_RS17560	COG0515	serine threonine protein kinase
CP969_RS17570	COG1309	transcriptional regulator
CP969_RS17575	COG1522	sequence-specific DNA binding
CP969_RS17580	COG1280	lysine exporter protein (LysE YggA)
CP969_RS17590	COG0259	pyridoxamine-phosphate oxidase activity
CP969_RS17600	COG2072	flavoprotein involved in K transport
CP969_RS17630	COG1366	Belongs to the anti-sigma-factor antagonist family
CP969_RS17690	COG0596	Alpha beta hydrolase
CP969_RS17690	COG2945	thiolester hydrolase activity
CP969_RS17700	COG4821	SIS domain
CP969_RS17715	COG0251	oxidation-reduction process
CP969_RS17725	COG0259	pyridoxamine-phosphate oxidase activity
CP969_RS17735	COG1024	Enoyl-CoA hydratase
CP969_RS17740	COG0318	PFAM AMP-dependent synthetase and ligase
CP969_RS17755	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP969_RS17775	COG0515	serine threonine protein kinase
CP969_RS17775	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP969_RS17780	COG5006	permease, DMT superfamily
CP969_RS17790	COG0277	FAD linked oxidase domain protein
CP969_RS17790	COG0247	lactate metabolic process
CP969_RS17815	COG2124	cytochrome p450
CP969_RS17825	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CP969_RS17855	COG0667	Aldo Keto reductase
CP969_RS17880	COG2252	PERMEase
CP969_RS17890	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CP969_RS17900	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CP969_RS17930	COG0739	heme binding
CP969_RS17955	COG0406	alpha-ribazole phosphatase activity
CP969_RS17965	COG2814	Major facilitator Superfamily
CP969_RS17975	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CP969_RS17980	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP969_RS17985	COG1278	Cold shock
CP969_RS18015	COG1061	Type III restriction enzyme res subunit
CP969_RS18030	COG0667	Aldo Keto reductase
CP969_RS18040	COG3973	AAA domain
CP969_RS18060	COG4257	antibiotic catabolic process
CP969_RS18090	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS18095	COG1309	transcriptional regulator
CP969_RS18115	COG1737	Transcriptional regulator
CP969_RS18120	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CP969_RS18135	COG0477	Major facilitator Superfamily
CP969_RS18150	COG0459	protein refolding
CP969_RS18155	COG1278	Cold shock
CP969_RS18170	COG0463	Glycosyl transferase, family 2
CP969_RS18210	COG1105	Belongs to the carbohydrate kinase PfkB family
CP969_RS18290	COG2378	regulation of single-species biofilm formation
CP969_RS18295	COG3842	ATPase activity
CP969_RS18320	COG0215	cysteine-tRNA ligase activity
CP969_RS18325	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CP969_RS18330	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CP969_RS18340	COG1329	Transcriptional regulator
CP969_RS18360	COG5002	protein histidine kinase activity
CP969_RS18375	COG0588	phosphoglycerate mutase activity
CP969_RS18460	COG0438	transferase activity, transferring glycosyl groups
CP969_RS18500	COG2318	DinB family
CP969_RS18510	COG1733	regulation of RNA biosynthetic process
CP969_RS18520	COG3973	AAA domain
CP969_RS18535	COG2188	Transcriptional regulator
CP969_RS18545	COG2188	Transcriptional regulator
CP969_RS18555	COG4552	Acetyltransferase involved in intracellular survival and related
CP969_RS18570	COG1490	D-aminoacyl-tRNA deacylase activity
CP969_RS18575	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP969_RS18585	COG3485	protocatechuate 3,4-dioxygenase
CP969_RS18630	COG2897	thiosulfate sulfurtransferase activity
CP969_RS18660	COG0745	RESPONSE REGULATOR receiver
CP969_RS18665	COG1609	Transcriptional regulator
CP969_RS18670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP969_RS18675	COG0745	RESPONSE REGULATOR receiver
CP969_RS18715	COG0737	Belongs to the 5'-nucleotidase family
CP969_RS18715	COG1525	nuclease
CP969_RS18715	COG4085	toxin activity
CP969_RS18720	COG0456	acetyltransferase
CP969_RS18735	COG1131	(ABC) transporter
CP969_RS18750	COG1725	Transcriptional regulator
CP969_RS18755	COG1131	(ABC) transporter
CP969_RS18770	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CP969_RS18780	COG0494	nUDIX hydrolase
CP969_RS18780	COG0406	alpha-ribazole phosphatase activity
CP969_RS18800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CP969_RS18805	COG0306	phosphate transporter
CP969_RS18815	COG1937	Protein conserved in bacteria
CP969_RS18835	COG0671	phosphoesterase, PA-phosphatase related
CP969_RS18840	COG1196	nuclear chromosome segregation
CP969_RS18840	COG0741	lytic transglycosylase activity
CP969_RS18840	COG0739	heme binding
CP969_RS18885	COG4585	Histidine kinase
CP969_RS18890	COG2197	response regulator
CP969_RS18930	COG1252	NADH dehydrogenase
CP969_RS18950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CP969_RS18960	COG1196	nuclear chromosome segregation
CP969_RS18960	COG0741	lytic transglycosylase activity
CP969_RS18960	COG0739	heme binding
CP969_RS18970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP969_RS18970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CP969_RS18975	COG2197	response regulator
CP969_RS18980	COG3851	Histidine kinase
CP969_RS19000	COG0513	Belongs to the DEAD box helicase family
CP969_RS19035	COG1643	Atp-dependent helicase
CP969_RS19060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP969_RS19070	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CP969_RS19100	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP969_RS19105	COG0047	phosphoribosylformylglycinamidine synthase activity
CP969_RS19110	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CP969_RS19145	COG2197	response regulator
CP969_RS19155	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CP969_RS19170	COG0151	Belongs to the GarS family
CP969_RS19195	COG0701	Predicted permease
CP969_RS19210	COG1801	Protein of unknown function DUF72
CP969_RS19250	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CP969_RS19280	COG1191	sigma factor activity
CP969_RS19285	COG1191	sigma factor activity
CP969_RS19305	COG2353	YceI-like domain
CP969_RS19335	COG0477	Major facilitator Superfamily
CP969_RS19340	COG0745	RESPONSE REGULATOR receiver
CP969_RS19360	COG1846	Transcriptional regulator
CP969_RS19370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CP969_RS19405	COG0318	PFAM AMP-dependent synthetase and ligase
CP969_RS19410	COG1595	DNA-templated transcription, initiation
CP969_RS19450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP969_RS19465	COG0653	protein targeting
CP969_RS19480	COG0006	proline dipeptidase activity
CP969_RS19500	COG1999	signal sequence binding
CP969_RS19515	COG2837	iron assimilation
CP969_RS19525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CP969_RS19530	COG0561	phosphatase activity
CP969_RS19560	COG1131	(ABC) transporter
CP969_RS19570	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CP969_RS19585	COG0561	phosphatase activity
CP969_RS19590	COG0741	lytic transglycosylase activity
CP969_RS19590	COG0739	heme binding
CP969_RS19590	COG1196	nuclear chromosome segregation
CP969_RS19595	COG4988	ABC transporter
CP969_RS19600	COG1294	oxidase, subunit
CP969_RS19605	COG1271	oxidase subunit
CP969_RS19610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CP969_RS19615	COG1609	Transcriptional regulator
CP969_RS19630	COG2304	oxidoreductase activity
CP969_RS19635	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CP969_RS19660	COG0662	Cupin 2, conserved barrel domain protein
CP969_RS19665	COG1950	PFAM Membrane protein of
CP969_RS19670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP969_RS19675	COG0626	cystathionine gamma-synthase activity
CP969_RS19700	COG2814	Major facilitator Superfamily
CP969_RS19725	COG0305	Participates in initiation and elongation during chromosome replication
CP969_RS19730	COG0534	Mate efflux family protein
CP969_RS19735	COG0359	binds to the 23S rRNA
CP969_RS19740	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CP969_RS19745	COG0629	single-stranded DNA binding
CP969_RS19750	COG0360	Binds together with S18 to 16S ribosomal RNA
CP969_RS19775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP969_RS19785	COG1260	myo-inositol-1-phosphate synthase
CP969_RS19800	COG0617	tRNA 3'-terminal CCA addition
CP969_RS19820	COG1595	DNA-templated transcription, initiation
CP969_RS19830	COG0492	ferredoxin-NADP+ reductase activity
CP969_RS19835	COG3118	belongs to the thioredoxin family
CP969_RS19850	COG1192	Involved in chromosome partitioning
CP969_RS19855	COG0357	Ribosomal RNA small subunit methyltransferase G
CP969_RS19865	COG0706	membrane insertase activity
CP969_RS19870	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CP969_RS19875	COG0594	ribonuclease P activity
CP969_RS19880	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CP969_RS19885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CP969_RS19895	COG0592	DNA-directed DNA polymerase activity
CP969_RS19900	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP969_RS19905	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CP969_RS19910	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
CP969_RS19915	COG0187	DNA topoisomerase II activity
CP969_RS19920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP969_RS19955	COG0515	serine threonine protein kinase
CP969_RS19980	COG0705	Rhomboid family
CP969_RS20005	COG3764	Sortase (surface protein transpeptidase)
CP969_RS20010	COG3764	Sortase (surface protein transpeptidase)
CP969_RS20015	COG0515	serine threonine protein kinase
CP969_RS20025	COG0768	penicillin binding
CP969_RS20040	COG1716	ATPase activity
CP969_RS20045	COG1716	ATPase activity
CP969_RS20080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CP969_RS20085	COG2151	metal-sulfur cluster biosynthetic enzyme
CP969_RS20090	COG3396	Phenylacetate-CoA oxygenase
CP969_RS20095	COG3460	Phenylacetate-CoA oxygenase
CP969_RS20100	COG3396	Phenylacetate-CoA oxygenase
CP969_RS20125	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP969_RS20130	COG1309	transcriptional regulator
CP969_RS20135	COG1522	sequence-specific DNA binding
CP969_RS20160	COG0303	'Molybdopterin
CP969_RS20180	COG3321	synthase
CP969_RS20180	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS20180	COG0604	alcohol dehydrogenase
CP969_RS20195	COG0515	serine threonine protein kinase
CP969_RS20200	COG0515	serine threonine protein kinase
CP969_RS20215	COG0022	dehydrogenase e1 component
CP969_RS20220	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP969_RS20245	COG2226	methyltransferase
CP969_RS20270	COG1362	aminopeptidase activity
CP969_RS20275	COG1960	acyl-CoA dehydrogenase activity
CP969_RS20285	COG1741	Belongs to the pirin family
CP969_RS20295	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CP969_RS20305	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CP969_RS20320	COG0583	DNA-binding transcription factor activity
CP969_RS20375	COG1957	nucleoside hydrolase
CP969_RS20380	COG0366	Alpha amylase catalytic
CP969_RS20410	COG1278	Cold shock
CP969_RS20415	COG2367	Beta-lactamase
CP969_RS20430	COG4213	ABC transporter substrate-binding protein
CP969_RS20440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CP969_RS20455	COG2197	response regulator
CP969_RS20470	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS20485	COG0583	DNA-binding transcription factor activity
CP969_RS20610	COG0235	Class ii aldolase
CP969_RS20615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP969_RS20620	COG1522	sequence-specific DNA binding
CP969_RS20630	COG0477	Major facilitator Superfamily
CP969_RS20640	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CP969_RS20650	COG3629	intracellular signal transduction
CP969_RS20650	COG3903	Transcriptional regulator
CP969_RS20675	COG0463	Glycosyl transferase, family 2
CP969_RS20700	COG0475	glutathione-regulated potassium exporter activity
CP969_RS20705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP969_RS20735	COG2197	response regulator
CP969_RS20740	COG4585	Histidine kinase
CP969_RS20795	COG0717	Belongs to the dCTP deaminase family
CP969_RS20800	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CP969_RS20815	COG2181	nitrate reductase activity
CP969_RS20815	COG0247	lactate metabolic process
CP969_RS20820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP969_RS20825	COG0443	Heat shock 70 kDa protein
CP969_RS20830	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CP969_RS20835	COG0484	heat shock protein binding
CP969_RS20840	COG0789	Transcriptional regulator
CP969_RS20845	COG4213	ABC transporter substrate-binding protein
CP969_RS20875	COG0542	response to heat
CP969_RS20935	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CP969_RS20945	COG2017	converts alpha-aldose to the beta-anomer
CP969_RS20950	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CP969_RS20955	COG0191	fructose-bisphosphate aldolase activity
CP969_RS20960	COG0477	Major facilitator Superfamily
CP969_RS20970	COG3483	tryptophan 2,3-dioxygenase activity
CP969_RS20975	COG3844	kynureninase activity
CP969_RS20990	COG4585	Histidine kinase
CP969_RS20995	COG2197	response regulator
CP969_RS21005	COG3559	Exporter of polyketide antibiotics
CP969_RS21010	COG1131	(ABC) transporter
CP969_RS21030	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CP969_RS21055	COG1802	Transcriptional regulator
CP969_RS21060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CP969_RS21065	COG0693	protein deglycase activity
CP969_RS21085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CP969_RS21090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CP969_RS21100	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP969_RS21105	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS21110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CP969_RS21155	COG1960	acyl-CoA dehydrogenase activity
CP969_RS21185	COG1595	DNA-templated transcription, initiation
CP969_RS21210	COG0701	Predicted permease
CP969_RS21255	COG3594	Acyltransferase
CP969_RS21335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP969_RS21340	COG1993	acr, cog1993
CP969_RS21345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP969_RS21350	COG1993	acr, cog1993
CP969_RS21375	COG3311	Transcriptional regulator
CP969_RS21410	COG1408	metallophosphoesterase
CP969_RS21420	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CP969_RS21435	COG0003	Pfam Anion-transporting ATPase
CP969_RS21460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CP969_RS21490	COG0596	Alpha beta hydrolase
CP969_RS21500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP969_RS21505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP969_RS21565	COG1111	helicase
CP969_RS21565	COG1205	dead DEAH box helicase
CP969_RS21570	COG1366	Belongs to the anti-sigma-factor antagonist family
CP969_RS21575	COG2172	sigma factor antagonist activity
CP969_RS21585	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CP969_RS21595	COG2264	protein methyltransferase activity
CP969_RS21605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CP969_RS21605	COG1754	DNA topoisomerase type I activity
CP969_RS21610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CP969_RS21640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP969_RS21640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CP969_RS21685	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS21690	COG2318	DinB family
CP969_RS21700	COG0076	glutamate decarboxylase activity
CP969_RS21710	COG0789	Transcriptional regulator
CP969_RS21715	COG0393	Putative heavy-metal-binding
CP969_RS21720	COG0586	Pfam SNARE associated Golgi protein
CP969_RS21730	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CP969_RS21735	COG2027	D-alanyl-D-alanine carboxypeptidase
CP969_RS21745	COG0037	tRNA processing
CP969_RS21760	COG0302	gtp cyclohydrolase
CP969_RS21770	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CP969_RS21775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CP969_RS21805	COG0649	NAD binding
CP969_RS21825	COG2197	response regulator
CP969_RS21830	COG1660	Displays ATPase and GTPase activities
CP969_RS21850	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CP969_RS21855	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CP969_RS21865	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CP969_RS21880	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CP969_RS21915	COG0739	heme binding
CP969_RS21920	COG2205	protein histidine kinase activity
CP969_RS21925	COG0745	RESPONSE REGULATOR receiver
CP969_RS21935	COG1595	DNA-templated transcription, initiation
CP969_RS21940	COG1194	a g-specific adenine glycosylase
CP969_RS21955	COG0671	phosphoesterase, PA-phosphatase related
CP969_RS21965	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CP969_RS21985	COG0248	Ppx GppA phosphatase
CP969_RS21990	COG1082	Xylose isomerase domain protein TIM barrel
CP969_RS21995	COG1309	transcriptional regulator
CP969_RS22000	COG0129	dihydroxy-acid dehydratase activity
CP969_RS22005	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CP969_RS22005	COG0515	serine threonine protein kinase
CP969_RS22010	COG4991	sh3 domain protein
CP969_RS22025	COG1129	ABC transporter
CP969_RS22025	COG0842	Transport permease protein
CP969_RS22035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CP969_RS22050	COG0180	Tryptophanyl-tRNA synthetase
CP969_RS22075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CP969_RS22080	COG0738	Major facilitator superfamily
CP969_RS22085	COG0123	including yeast histone deacetylase and acetoin utilization protein
CP969_RS22135	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CP969_RS22140	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CP969_RS22145	COG0181	hydroxymethylbilane synthase activity
CP969_RS22150	COG1648	precorrin-2 dehydrogenase activity
CP969_RS22150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CP969_RS22175	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CP969_RS22215	COG0113	porphobilinogen synthase activity
CP969_RS22230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CP969_RS22245	COG0018	arginyl-trna synthetase
CP969_RS22250	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CP969_RS22270	COG1690	Belongs to the RtcB family
CP969_RS22280	COG1742	UPF0060 membrane protein
CP969_RS22285	COG1846	Transcriptional regulator
CP969_RS22290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP969_RS22305	COG2205	protein histidine kinase activity
CP969_RS22310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP969_RS22315	COG1116	anion transmembrane transporter activity
CP969_RS22320	COG2340	Cysteine-rich secretory protein family
CP969_RS22365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CP969_RS22370	COG0406	alpha-ribazole phosphatase activity
CP969_RS22380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CP969_RS22385	COG0785	Cytochrome C biogenesis protein
CP969_RS22390	COG1333	cytochrome c biogenesis protein
CP969_RS22395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CP969_RS22405	COG0789	Transcriptional regulator
CP969_RS22420	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CP969_RS22435	COG0163	prenyltransferase activity
CP969_RS22445	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP969_RS22465	COG1309	transcriptional regulator
CP969_RS22480	COG0183	Belongs to the thiolase family
CP969_RS22490	COG2226	methyltransferase
CP969_RS22495	COG1278	Cold shock
CP969_RS22500	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
CP969_RS22520	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CP969_RS22530	COG2226	methyltransferase
CP969_RS22560	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP969_RS22565	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP969_RS22570	COG0649	NAD binding
CP969_RS22580	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CP969_RS22585	COG1034	ATP synthesis coupled electron transport
CP969_RS22590	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP969_RS22595	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP969_RS22600	COG0839	Belongs to the complex I subunit 6 family
CP969_RS22605	COG0713	ATP synthesis coupled electron transport
CP969_RS22610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP969_RS22620	COG1007	ATP synthesis coupled electron transport
CP969_RS22625	COG0514	ATP-dependent DNA helicase (RecQ)
CP969_RS22680	COG0561	phosphatase activity
CP969_RS22685	COG3953	SLT domain
CP969_RS22685	COG5412	phage tail tape measure protein
CP969_RS22690	COG0142	geranyltranstransferase activity
CP969_RS22715	COG1846	Transcriptional regulator
CP969_RS22725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP969_RS22750	COG0702	epimerase
CP969_RS22755	COG1733	regulation of RNA biosynthetic process
CP969_RS22770	COG1013	pyruvate-flavodoxin oxidoreductase activity
CP969_RS22775	COG0674	pyruvate-flavodoxin oxidoreductase activity
CP969_RS22775	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CP969_RS22795	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP969_RS22800	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP969_RS22805	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP969_RS22810	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CP969_RS22815	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CP969_RS22825	COG0713	ATP synthesis coupled electron transport
CP969_RS22830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CP969_RS22840	COG1007	ATP synthesis coupled electron transport
CP969_RS22845	COG0501	Belongs to the peptidase M48B family
CP969_RS22850	COG3304	Inner membrane component domain
CP969_RS22865	COG2261	transglycosylase associated protein
CP969_RS22870	COG1666	GTP binding
CP969_RS22885	COG0702	epimerase
CP969_RS22905	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CP969_RS22910	COG2030	dehydratase
CP969_RS22925	COG0477	Major facilitator Superfamily
CP969_RS22935	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CP969_RS22940	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP969_RS22945	COG0436	Aminotransferase
CP969_RS22960	COG0250	Participates in transcription elongation, termination and antitermination
CP969_RS22965	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CP969_RS22970	COG0081	regulation of translation
CP969_RS22985	COG0222	ribosome binding
CP969_RS22995	COG0085	RNA polymerase activity
CP969_RS23000	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CP969_RS23010	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CP969_RS23015	COG0049	tRNA binding
CP969_RS23020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CP969_RS23025	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CP969_RS23055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CP969_RS23070	COG0051	transcription antitermination factor activity, RNA binding
CP969_RS23075	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CP969_RS23080	COG0088	Forms part of the polypeptide exit tunnel
CP969_RS23085	COG0089	rRNA binding
CP969_RS23090	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CP969_RS23095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CP969_RS23100	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CP969_RS23105	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CP969_RS23110	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CP969_RS23115	COG0255	Belongs to the universal ribosomal protein uL29 family
CP969_RS23120	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CP969_RS23125	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CP969_RS23130	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CP969_RS23135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CP969_RS23140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CP969_RS23150	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CP969_RS23155	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CP969_RS23160	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CP969_RS23165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CP969_RS23170	COG1841	ribosomal large subunit assembly
CP969_RS23175	COG0200	Binds to the 23S rRNA
CP969_RS23180	COG0201	protein transport
CP969_RS23185	COG0563	adenylate kinase activity
CP969_RS23195	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CP969_RS23200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CP969_RS23205	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CP969_RS23210	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CP969_RS23215	COG0202	RNA polymerase activity
CP969_RS23220	COG0203	ribosomal protein L17
CP969_RS23225	COG0101	tRNA pseudouridine synthase activity
CP969_RS23235	COG2843	Capsule synthesis protein
CP969_RS23270	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CP969_RS23275	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CP969_RS23280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP969_RS23290	COG1072	(Pantothenic acid kinase))
CP969_RS23300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CP969_RS23315	COG0736	holo-[acyl-carrier-protein] synthase activity
CP969_RS23320	COG1191	sigma factor activity
CP969_RS23335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CP969_RS23340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CP969_RS23345	COG0802	atpase or kinase
CP969_RS23370	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CP969_RS23395	COG0726	polysaccharide deacetylase
CP969_RS23400	COG0726	polysaccharide deacetylase
CP969_RS23405	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CP969_RS23410	COG0459	protein refolding
CP969_RS23460	COG1196	nuclear chromosome segregation
CP969_RS23475	COG4221	oxidoreductase activity
CP969_RS23480	COG2132	Multicopper oxidase
CP969_RS23490	COG0583	DNA-binding transcription factor activity
CP969_RS23505	COG1595	DNA-templated transcription, initiation
CP969_RS23515	COG0516	GMP reductase activity
CP969_RS23525	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CP969_RS23540	COG0515	serine threonine protein kinase
CP969_RS23540	COG2815	serine threonine protein kinase
CP969_RS23545	COG0515	serine threonine protein kinase
CP969_RS23550	COG0515	serine threonine protein kinase
CP969_RS23555	COG0515	serine threonine protein kinase
CP969_RS23560	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS23590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CP969_RS23590	COG0519	Catalyzes the synthesis of GMP from XMP
CP969_RS23625	COG2197	response regulator
CP969_RS23655	COG0739	heme binding
CP969_RS23665	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP969_RS23665	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP969_RS23680	COG0714	Associated with various cellular activities
CP969_RS23685	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CP969_RS23690	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP969_RS23700	COG0045	succinate-CoA ligase (ADP-forming) activity
CP969_RS23730	COG0138	bifunctional purine biosynthesis protein purh
CP969_RS23740	COG2815	serine threonine protein kinase
CP969_RS23740	COG0515	serine threonine protein kinase
CP969_RS23755	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CP969_RS23770	COG0039	L-malate dehydrogenase activity
CP969_RS23790	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS23800	COG4175	Glycine betaine
CP969_RS23800	COG0517	IMP dehydrogenase activity
CP969_RS23805	COG4176	ABC-type proline glycine betaine transport system permease component
CP969_RS23820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP969_RS23825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CP969_RS23835	COG0754	glutathionylspermidine amidase activity
CP969_RS23840	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP969_RS23860	COG0180	Tryptophanyl-tRNA synthetase
CP969_RS23880	COG0671	phosphoesterase, PA-phosphatase related
CP969_RS23895	COG1686	Belongs to the peptidase S11 family
CP969_RS23900	COG1408	metallophosphoesterase
CP969_RS23905	COG1309	transcriptional regulator
CP969_RS23930	COG1053	succinate dehydrogenase
CP969_RS23940	COG2009	succinate dehydrogenase
CP969_RS23995	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP969_RS23995	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP969_RS24020	COG1216	Glycosyl transferase, family 2
CP969_RS24030	COG1216	Glycosyl transferase, family 2
CP969_RS24045	COG2089	acid synthase
CP969_RS24055	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CP969_RS24055	COG1473	amidohydrolase
CP969_RS24060	COG1744	ABC transporter substrate-binding protein PnrA-like
CP969_RS24065	COG1744	ABC transporter substrate-binding protein PnrA-like
CP969_RS24070	COG3845	ABC transporter
CP969_RS24080	COG1079	Belongs to the binding-protein-dependent transport system permease family
CP969_RS24115	COG2814	Major facilitator Superfamily
CP969_RS24120	COG0583	DNA-binding transcription factor activity
CP969_RS24130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP969_RS24155	COG2205	protein histidine kinase activity
CP969_RS24160	COG0745	RESPONSE REGULATOR receiver
CP969_RS24165	COG1595	DNA-templated transcription, initiation
CP969_RS24180	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS24185	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS24190	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CP969_RS24200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CP969_RS24225	COG4770	biotin carboxylase activity
CP969_RS24235	COG0424	maF-like protein
CP969_RS24245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP969_RS24255	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP969_RS24265	COG1024	Enoyl-CoA hydratase
CP969_RS24275	COG2986	histidine ammonia-lyase
CP969_RS24300	COG1136	(ABC) transporter
CP969_RS24305	COG1404	Belongs to the peptidase S8 family
CP969_RS24340	COG2255	four-way junction helicase activity
CP969_RS24345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CP969_RS24360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CP969_RS24370	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP969_RS24385	COG1331	Highly conserved protein containing a thioredoxin domain
CP969_RS24395	COG1309	transcriptional regulator
CP969_RS24400	COG0477	Major facilitator Superfamily
CP969_RS24410	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CP969_RS24490	COG0384	phenazine biosynthesis protein PhzF
CP969_RS24510	COG0436	Aminotransferase
CP969_RS24520	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CP969_RS24535	COG1414	Transcriptional regulator
CP969_RS24540	COG0251	oxidation-reduction process
CP969_RS24545	COG2610	gluconate transmembrane transporter activity
CP969_RS24580	COG2894	cell division
CP969_RS24610	COG3920	Histidine kinase
CP969_RS24615	COG2197	response regulator
CP969_RS24670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CP969_RS24675	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CP969_RS24690	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP969_RS24695	COG0450	alkyl hydroperoxide reductase
CP969_RS24710	COG1136	(ABC) transporter
CP969_RS24730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP969_RS24745	COG0114	fumarate hydratase activity
CP969_RS24755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CP969_RS24755	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CP969_RS24780	COG0778	Nitroreductase
CP969_RS24785	COG1722	exodeoxyribonuclease VII activity
CP969_RS24790	COG1570	exodeoxyribonuclease VII activity
CP969_RS24795	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CP969_RS24810	COG0012	GTP binding
CP969_RS24845	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP969_RS24915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CP969_RS24920	COG1053	succinate dehydrogenase
CP969_RS24940	COG1217	gtp-binding protein TYPA
CP969_RS24945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP969_RS24950	COG0747	negative chemotaxis
CP969_RS24955	COG0601	transmembrane transport
CP969_RS24960	COG0444	Belongs to the ABC transporter superfamily
CP969_RS24965	COG4608	Belongs to the ABC transporter superfamily
CP969_RS24975	COG0601	transmembrane transport
CP969_RS24980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP969_RS24985	COG0444	Belongs to the ABC transporter superfamily
CP969_RS24990	COG4608	Belongs to the ABC transporter superfamily
CP969_RS25035	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CP969_RS25050	COG0477	Major facilitator Superfamily
CP969_RS25090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP969_RS25110	COG0519	Catalyzes the synthesis of GMP from XMP
CP969_RS25115	COG1024	Enoyl-CoA hydratase
CP969_RS25130	COG1595	DNA-templated transcription, initiation
CP969_RS25140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CP969_RS25145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CP969_RS25180	COG0598	Magnesium transport protein CorA
CP969_RS25190	COG2814	Major facilitator Superfamily
CP969_RS25200	COG0613	PHP domain protein
CP969_RS25205	COG2095	MarC family integral membrane protein
CP969_RS25215	COG1432	Conserved Protein
CP969_RS25290	COG0596	Alpha beta hydrolase
CP969_RS25320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP969_RS25355	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP969_RS25405	COG3480	Lon protease (S16) C-terminal proteolytic domain
CP969_RS25415	COG1615	UPF0182 protein
CP969_RS25450	COG0483	inositol monophosphate 1-phosphatase activity
CP969_RS25470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CP969_RS25480	COG2135	peptidase activity
CP969_RS25490	COG1595	DNA-templated transcription, initiation
CP969_RS25495	COG5662	AntiSigma factor
CP969_RS25500	COG2199	diguanylate cyclase activity
CP969_RS25500	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CP969_RS25515	COG0242	peptide deformylase activity
CP969_RS25525	COG2124	cytochrome p450
CP969_RS25565	COG2188	Transcriptional regulator
CP969_RS25570	COG0363	glucosamine-6-phosphate deaminase activity
CP969_RS25575	COG1309	transcriptional regulator
CP969_RS25590	COG1597	lipid kinase activity
CP969_RS25620	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CP969_RS25630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CP969_RS25635	COG0142	geranyltranstransferase activity
CP969_RS25640	COG0456	acetyltransferase
CP969_RS25650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CP969_RS25680	COG4106	trans-aconitate 2-methyltransferase activity
CP969_RS25685	COG1126	abc transporter atp-binding protein
CP969_RS25705	COG0281	malic enzyme
CP969_RS25710	COG0604	alcohol dehydrogenase
CP969_RS25740	COG0508	dehydrogenase complex catalyzes the overall conversion of
CP969_RS25740	COG0567	Dehydrogenase, E1 component
CP969_RS25745	COG2205	protein histidine kinase activity
CP969_RS25750	COG0745	RESPONSE REGULATOR receiver
CP969_RS25760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CP969_RS25820	COG1309	transcriptional regulator
CP969_RS25830	COG0768	penicillin binding
CP969_RS25855	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CP969_RS25860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CP969_RS25890	COG0745	RESPONSE REGULATOR receiver
CP969_RS25895	COG0018	arginyl-trna synthetase
CP969_RS25900	COG0019	diaminopimelate decarboxylase activity
CP969_RS25905	COG0460	homoserine dehydrogenase
CP969_RS25910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CP969_RS25915	COG0083	homoserine kinase activity
CP969_RS25925	COG1316	TRANSCRIPTIONal
CP969_RS25930	COG0254	rRNA binding
CP969_RS25935	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CP969_RS25940	COG2890	protein-(glutamine-N5) methyltransferase activity
CP969_RS25950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CP969_RS25955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP969_RS25960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CP969_RS25975	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP969_RS25980	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CP969_RS25985	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CP969_RS25990	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CP969_RS25995	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CP969_RS26000	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CP969_RS26005	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CP969_RS26020	COG2197	response regulator
CP969_RS26025	COG4585	Histidine kinase
CP969_RS26055	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP969_RS26075	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CP969_RS26130	COG0183	Belongs to the thiolase family
CP969_RS26145	COG0745	RESPONSE REGULATOR receiver
CP969_RS26150	COG2205	protein histidine kinase activity
CP969_RS26195	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP969_RS26195	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP969_RS26240	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CP969_RS26245	COG0857	belongs to the CobB CobQ family
CP969_RS26245	COG0280	phosphate acetyltransferase
CP969_RS26250	COG0205	6-phosphofructokinase activity
CP969_RS26260	COG4565	transcriptional regulatory protein
CP969_RS26265	COG3290	protein histidine kinase activity
CP969_RS26270	COG1301	dicarboxylic acid transport
CP969_RS26280	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CP969_RS26285	COG3281	Trehalose synthase
CP969_RS26295	COG0366	Alpha amylase catalytic
CP969_RS26305	COG0058	SHG alpha-glucan phosphorylase activity
CP969_RS26325	COG1132	(ABC) transporter
CP969_RS26330	COG1132	(ABC) transporter
CP969_RS26335	COG1132	(ABC) transporter
CP969_RS26340	COG1132	(ABC) transporter
CP969_RS26345	COG1131	(ABC) transporter
CP969_RS26355	COG4585	Histidine kinase
CP969_RS26360	COG2197	response regulator
CP969_RS26370	COG1376	ErfK ybiS ycfS ynhG family protein
CP969_RS26405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP969_RS26410	COG3757	hydrolase, family 25
CP969_RS26410	COG3409	Peptidoglycan-binding domain 1 protein
CP969_RS26420	COG1760	l-serine dehydratase
CP969_RS26425	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CP969_RS26430	COG0509	glycine decarboxylation via glycine cleavage system
CP969_RS26435	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CP969_RS26455	COG4166	transmembrane transport
CP969_RS26460	COG0601	transmembrane transport
CP969_RS26465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP969_RS26470	COG0444	Belongs to the ABC transporter superfamily
CP969_RS26475	COG4608	Belongs to the ABC transporter superfamily
CP969_RS26480	COG2860	membrane
CP969_RS26490	COG1309	transcriptional regulator
CP969_RS26515	COG0482	sulfurtransferase activity
CP969_RS26535	COG1611	Belongs to the LOG family
CP969_RS26540	COG4221	oxidoreductase activity
CP969_RS26550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CP969_RS26560	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP969_RS26565	COG0154	amidase activity
CP969_RS26575	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CP969_RS26580	COG2226	methyltransferase
CP969_RS26590	COG2409	Drug exporters of the RND superfamily
CP969_RS26595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP969_RS26605	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CP969_RS26605	COG1672	PFAM Archaeal ATPase
CP969_RS26615	COG2133	pyrroloquinoline quinone binding
CP969_RS26620	COG0667	Aldo Keto reductase
CP969_RS26625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CP969_RS26630	COG5001	Diguanylate cyclase
CP969_RS26640	COG0440	acetolactate synthase activity
CP969_RS26645	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CP969_RS26650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CP969_RS26665	COG0506	proline dehydrogenase activity
CP969_RS26670	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS26680	COG0473	3-isopropylmalate dehydrogenase activity
CP969_RS26685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CP969_RS26690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CP969_RS26705	COG1032	radical SAM domain protein
CP969_RS26710	COG0300	oxidoreductase activity
CP969_RS26715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CP969_RS26735	COG2018	Roadblock/LC7 domain
CP969_RS26755	COG2018	Roadblock/LC7 domain
CP969_RS26760	COG5002	protein histidine kinase activity
CP969_RS26770	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP969_RS26775	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CP969_RS26815	COG1414	Transcriptional regulator
CP969_RS26820	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CP969_RS26825	COG0066	3-isopropylmalate dehydratase activity
CP969_RS26835	COG0776	regulation of translation
CP969_RS26845	COG1920	GTP binding
CP969_RS26855	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CP969_RS26860	COG1181	Belongs to the D-alanine--D-alanine ligase family
CP969_RS26875	COG0351	phosphomethylpyrimidine kinase
CP969_RS26880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CP969_RS26885	COG1461	Dihydroxyacetone kinase
CP969_RS26900	COG0742	ribosomal rna small subunit methyltransferase
CP969_RS26905	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CP969_RS26920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CP969_RS26925	COG0571	ribonuclease III activity
CP969_RS26930	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP969_RS26935	COG1733	regulation of RNA biosynthetic process
CP969_RS26940	COG2340	Cysteine-rich secretory protein family
CP969_RS26945	COG1254	Belongs to the acylphosphatase family
CP969_RS26960	COG1196	nuclear chromosome segregation
CP969_RS26965	COG0477	Major facilitator Superfamily
CP969_RS26995	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CP969_RS27015	COG0228	four-way junction DNA binding
CP969_RS27020	COG1837	Belongs to the UPF0109 family
CP969_RS27025	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CP969_RS27030	COG0336	Belongs to the RNA methyltransferase TrmD family
CP969_RS27035	COG0335	large ribosomal subunit rRNA binding
CP969_RS27050	COG0681	Belongs to the peptidase S26 family
CP969_RS27070	COG0792	nuclease activity
CP969_RS27085	COG1191	sigma factor activity
CP969_RS27100	COG0052	Belongs to the universal ribosomal protein uS2 family
CP969_RS27105	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CP969_RS27110	COG0528	UMP kinase activity
CP969_RS27115	COG0233	cytoplasmic translational termination
CP969_RS27120	COG0575	Belongs to the CDS family
CP969_RS27130	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CP969_RS27140	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CP969_RS27145	COG3842	ATPase activity
CP969_RS27170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CP969_RS27180	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS27190	COG0584	glycerophosphoryl diester phosphodiesterase
CP969_RS27195	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CP969_RS27210	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS27220	COG3842	ATPase activity
CP969_RS27225	COG1176	ABC-type spermidine putrescine transport system, permease component I
CP969_RS27230	COG1177	transmembrane transport
CP969_RS27235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP969_RS27270	COG2508	Transcriptional regulator
CP969_RS27275	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS27290	COG4209	transmembrane transport
CP969_RS27295	COG0395	ABC-type sugar transport system, permease component
CP969_RS27340	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CP969_RS27345	COG0750	zinc metalloprotease
CP969_RS27350	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CP969_RS27365	COG0442	prolyl-tRNA aminoacylation
CP969_RS27385	COG0779	Required for maturation of 30S ribosomal subunits
CP969_RS27400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CP969_RS27410	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CP969_RS27415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CP969_RS27430	COG0455	bacterial-type flagellum organization
CP969_RS27450	COG1404	Belongs to the peptidase S8 family
CP969_RS27465	COG1404	Belongs to the peptidase S8 family
CP969_RS27505	COG1674	ftsk spoiiie
CP969_RS27520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CP969_RS27525	COG1185	polyribonucleotide nucleotidyltransferase activity
CP969_RS27530	COG0612	Peptidase, M16
CP969_RS27535	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CP969_RS27555	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CP969_RS27560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP969_RS27565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CP969_RS27600	COG2770	Histidine kinase
CP969_RS27600	COG2208	phosphoserine phosphatase activity
CP969_RS27610	COG3850	Histidine kinase
CP969_RS27610	COG3437	response regulator, receiver
CP969_RS27610	COG2205	protein histidine kinase activity
CP969_RS27610	COG4999	Histidine kinase
CP969_RS27620	COG1674	ftsk spoiiie
CP969_RS27630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP969_RS27640	COG1546	Belongs to the CinA family
CP969_RS27640	COG1058	Belongs to the CinA family
CP969_RS27645	COG1396	sequence-specific DNA binding
CP969_RS27650	COG0783	Belongs to the Dps family
CP969_RS27660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CP969_RS27665	COG1201	RNA secondary structure unwinding
CP969_RS27695	COG0628	permease
CP969_RS27710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CP969_RS27725	COG0765	amino acid transport
CP969_RS27730	COG0765	amino acid transport
CP969_RS27735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CP969_RS27740	COG1126	abc transporter atp-binding protein
CP969_RS27745	COG0745	RESPONSE REGULATOR receiver
CP969_RS27750	COG2205	protein histidine kinase activity
CP969_RS27755	COG2358	TRAP transporter, solute receptor (TAXI family
CP969_RS27765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP969_RS27785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CP969_RS27795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CP969_RS27800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CP969_RS27805	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CP969_RS27840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CP969_RS27845	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CP969_RS27850	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CP969_RS27865	COG0588	phosphoglycerate mutase activity
CP969_RS27880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CP969_RS27895	COG0514	ATP-dependent DNA helicase (RecQ)
CP969_RS27940	COG1802	Transcriptional regulator
CP969_RS27945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CP969_RS27960	COG0187	DNA topoisomerase II activity
CP969_RS27970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP969_RS27975	COG4565	transcriptional regulatory protein
CP969_RS27980	COG3290	protein histidine kinase activity
CP969_RS27995	COG0372	Belongs to the citrate synthase family
CP969_RS28005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CP969_RS28010	COG0612	Peptidase, M16
CP969_RS28025	COG1802	Transcriptional regulator
CP969_RS28030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CP969_RS28055	COG1435	thymidine kinase activity
CP969_RS28080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP969_RS28085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CP969_RS28090	COG4413	Urea transporter
CP969_RS28105	COG0832	Belongs to the urease beta subunit family
CP969_RS28110	COG0804	urea catabolic process
CP969_RS28120	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP969_RS28125	COG0829	nickel cation binding
CP969_RS28175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CP969_RS28185	COG0745	RESPONSE REGULATOR receiver
CP969_RS28190	COG2205	protein histidine kinase activity
CP969_RS28215	COG0756	dUTP diphosphatase activity
CP969_RS28255	COG0569	domain protein
CP969_RS28260	COG0531	amino acid
CP969_RS28265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CP969_RS28275	COG0726	polysaccharide deacetylase
CP969_RS28325	COG2368	4-hydroxyphenylacetate
CP969_RS28335	COG2267	carboxylic ester hydrolase activity
CP969_RS28345	COG0346	lactoylglutathione lyase activity
CP969_RS28355	COG1116	anion transmembrane transporter activity
CP969_RS28355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CP969_RS28365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP969_RS28385	COG2267	carboxylic ester hydrolase activity
CP969_RS28420	COG1414	Transcriptional regulator
CP969_RS28430	COG0179	Fumarylacetoacetate (FAA) hydrolase
CP969_RS28440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CP969_RS28455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CP969_RS28460	COG1309	transcriptional regulator
CP969_RS28490	COG1609	Transcriptional regulator
CP969_RS28500	COG1175	transmembrane transport
CP969_RS28510	COG1472	Belongs to the glycosyl hydrolase 3 family
CP969_RS28515	COG2188	Transcriptional regulator
CP969_RS28520	COG2182	Extracellular solute-binding protein
CP969_RS28525	COG1175	transmembrane transport
CP969_RS28530	COG0395	ABC-type sugar transport system, permease component
CP969_RS28535	COG1472	Belongs to the glycosyl hydrolase 3 family
CP969_RS28540	COG1253	flavin adenine dinucleotide binding
CP969_RS28555	COG1799	cell septum assembly
CP969_RS28590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CP969_RS28595	COG2235	arginine
CP969_RS28600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CP969_RS28610	COG1024	Enoyl-CoA hydratase
CP969_RS28640	COG2267	carboxylic ester hydrolase activity
CP969_RS28670	COG2255	four-way junction helicase activity
CP969_RS28675	COG2755	lipolytic protein G-D-S-L family
CP969_RS28680	COG2124	cytochrome p450
CP969_RS28725	COG0601	transmembrane transport
CP969_RS28730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CP969_RS28740	COG4608	Belongs to the ABC transporter superfamily
CP969_RS28770	COG0583	DNA-binding transcription factor activity
CP969_RS28800	COG1653	transport
CP969_RS28815	COG0515	serine threonine protein kinase
CP969_RS28835	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS28845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CP969_RS28845	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CP969_RS28860	COG2608	mercury ion transmembrane transporter activity
CP969_RS28895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CP969_RS28905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CP969_RS28915	COG3458	cephalosporin-C deacetylase activity
CP969_RS28920	COG4209	transmembrane transport
CP969_RS28925	COG0395	ABC-type sugar transport system, permease component
CP969_RS28960	COG1653	transport
CP969_RS28965	COG1175	transmembrane transport
CP969_RS28970	COG0395	ABC-type sugar transport system, permease component
CP969_RS28975	COG1940	carbohydrate kinase activity
CP969_RS28980	COG4213	ABC transporter substrate-binding protein
CP969_RS28990	COG4214	carbohydrate transport
CP969_RS28995	COG2259	Doxx family
CP969_RS29000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP969_RS29005	COG0531	amino acid
CP969_RS29010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP969_RS29020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP969_RS29025	COG0318	PFAM AMP-dependent synthetase and ligase
CP969_RS29030	COG0596	Alpha beta hydrolase
CP969_RS29035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP969_RS29040	COG3321	synthase
CP969_RS29040	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS29040	COG0604	alcohol dehydrogenase
CP969_RS29055	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP969_RS29055	COG1024	Enoyl-CoA hydratase
CP969_RS29060	COG0183	Belongs to the thiolase family
CP969_RS29065	COG1609	Transcriptional regulator
CP969_RS29070	COG3250	beta-galactosidase activity
CP969_RS29080	COG1175	transmembrane transport
CP969_RS29085	COG0395	ABC-type sugar transport system, permease component
CP969_RS29090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CP969_RS29095	COG0569	domain protein
CP969_RS29100	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CP969_RS29115	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CP969_RS29135	COG0446	pyridine nucleotide-disulphide oxidoreductase
CP969_RS29145	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP969_RS29150	COG3253	May function as heme-dependent peroxidase
CP969_RS29165	COG3220	belongs to the UPF0276 family
CP969_RS29240	COG0723	plastoquinol--plastocyanin reductase activity
CP969_RS29240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CP969_RS29245	COG0640	Transcriptional regulator
CP969_RS29260	COG0330	HflC and HflK could
CP969_RS29290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CP969_RS29295	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CP969_RS29305	COG1174	glycine betaine transport
CP969_RS29310	COG1174	glycine betaine transport
CP969_RS29315	COG1732	Glycine betaine
CP969_RS29360	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP969_RS29425	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CP969_RS29445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CP969_RS29450	COG1116	anion transmembrane transporter activity
CP969_RS29470	COG0529	Catalyzes the synthesis of activated sulfate
CP969_RS29475	COG0175	sulfate reduction
CP969_RS29505	COG1960	acyl-CoA dehydrogenase activity
CP969_RS29515	COG1917	Cupin 2, conserved barrel domain protein
CP969_RS29515	COG4977	sequence-specific DNA binding
CP969_RS29540	COG2814	Major facilitator Superfamily
CP969_RS29545	COG1609	Transcriptional regulator
CP969_RS29555	COG1733	regulation of RNA biosynthetic process
CP969_RS29560	COG0251	oxidation-reduction process
CP969_RS29600	COG2040	homocysteine
CP969_RS29670	COG0494	nUDIX hydrolase
CP969_RS29695	COG0277	FAD linked oxidase domain protein
CP969_RS29710	COG1162	GTPase activity
CP969_RS29735	COG0028	Belongs to the TPP enzyme family
CP969_RS29760	COG0477	Major facilitator Superfamily
CP969_RS29770	COG0804	urea catabolic process
CP969_RS29775	COG0832	Belongs to the urease beta subunit family
CP969_RS29775	COG0831	urea catabolic process
CP969_RS29795	COG1802	Transcriptional regulator
CP969_RS29825	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CP969_RS29840	COG0726	polysaccharide deacetylase
CP969_RS29850	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CP969_RS29865	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CP969_RS29865	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CP969_RS29900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CP969_RS29905	COG0318	PFAM AMP-dependent synthetase and ligase
CP969_RS29935	COG2318	DinB family
CP969_RS29945	COG3903	Transcriptional regulator
CP969_RS29945	COG3629	intracellular signal transduction
CP969_RS29950	COG0142	geranyltranstransferase activity
CP969_RS29955	COG2409	Drug exporters of the RND superfamily
CP969_RS29960	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CP969_RS29985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP969_RS30015	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CP969_RS30020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CP969_RS30025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP969_RS30065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CP969_RS30075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CP969_RS30090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CP969_RS30120	COG2351	hydroxyisourate hydrolase activity
CP969_RS30150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CP969_RS30220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CP969_RS30260	COG0436	Aminotransferase
CP969_RS30275	COG2304	oxidoreductase activity
CP969_RS30280	COG4264	IucA IucC family
CP969_RS30300	COG0519	Catalyzes the synthesis of GMP from XMP
CP969_RS30300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CP969_RS30330	COG0783	Belongs to the Dps family
CP969_RS30360	COG0702	epimerase
CP969_RS30370	COG1120	ATPase activity
CP969_RS30375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CP969_RS30380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CP969_RS30415	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CP969_RS30430	COG1414	Transcriptional regulator
CP969_RS30435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP969_RS30440	COG4266	Belongs to the allantoicase family
CP969_RS30445	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS30460	COG2197	response regulator
CP969_RS30475	COG2188	Transcriptional regulator
CP969_RS30480	COG1879	ABC-type sugar transport system periplasmic component
CP969_RS30495	COG1940	carbohydrate kinase activity
CP969_RS30505	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CP969_RS30515	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CP969_RS30520	COG0829	nickel cation binding
CP969_RS30525	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CP969_RS30535	COG0804	urea catabolic process
CP969_RS30555	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP969_RS30560	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CP969_RS30585	COG0405	Gamma-glutamyltransferase
CP969_RS30590	COG0542	response to heat
CP969_RS30610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CP969_RS30620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CP969_RS30635	COG2340	Cysteine-rich secretory protein family
CP969_RS30665	COG0095	Lipoate-protein ligase
CP969_RS30680	COG0444	Belongs to the ABC transporter superfamily
CP969_RS30690	COG4166	transmembrane transport
CP969_RS30700	COG3458	cephalosporin-C deacetylase activity
CP969_RS30710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CP969_RS30720	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CP969_RS30740	COG0483	inositol monophosphate 1-phosphatase activity
CP969_RS30750	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CP969_RS30770	COG1086	Polysaccharide biosynthesis protein
CP969_RS30775	COG1215	transferase activity, transferring glycosyl groups
CP969_RS30790	COG1131	(ABC) transporter
CP969_RS30820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CP969_RS30840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CP969_RS30845	COG1132	(ABC) transporter
CP969_RS30850	COG1132	(ABC) transporter
CP969_RS30855	COG0156	8-amino-7-oxononanoate synthase activity
CP969_RS30880	COG2159	amidohydrolase
CP969_RS30895	COG0477	Major facilitator Superfamily
CP969_RS30895	COG2814	Major facilitator Superfamily
CP969_RS30905	COG0640	Transcriptional regulator
CP969_RS30920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CP969_RS30925	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CP969_RS30940	COG1929	Belongs to the glycerate kinase type-1 family
CP969_RS30950	COG0688	phosphatidylethanolamine metabolic process
CP969_RS30955	COG1960	acyl-CoA dehydrogenase activity
CP969_RS30970	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP969_RS30970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CP969_RS30975	COG0604	alcohol dehydrogenase
CP969_RS30985	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP969_RS31005	COG0596	Alpha beta hydrolase
CP969_RS31035	COG2362	D-Aminopeptidase
CP969_RS31040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CP969_RS31050	COG1619	proteins homologs of microcin C7 resistance protein MccF
CP969_RS31055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CP969_RS31060	COG0010	Belongs to the arginase family
CP969_RS31065	COG0457	Tetratricopeptide repeat
CP969_RS31080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP969_RS31090	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CP969_RS31095	COG1793	dna ligase
CP969_RS31095	COG3285	dna ligase
CP969_RS31160	COG0488	(ABC) transporter
CP969_RS31170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP969_RS31205	COG1191	sigma factor activity
CP969_RS31230	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CP969_RS31255	COG0443	Heat shock 70 kDa protein
CP969_RS31280	COG2154	pterin-4-alpha-carbinolamine dehydratase
CP969_RS31285	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CP969_RS31285	COG4106	trans-aconitate 2-methyltransferase activity
CP969_RS31295	COG3340	Belongs to the peptidase S51 family
CP969_RS31310	COG4733	cellulase activity
CP969_RS31310	COG5297	Belongs to the glycosyl hydrolase family 6
CP969_RS31320	COG5297	Belongs to the glycosyl hydrolase family 6
CP969_RS31330	COG0656	L-ascorbic acid biosynthetic process
CP969_RS31350	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CP969_RS31365	COG3383	formate dehydrogenase (NAD+) activity
CP969_RS31370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CP969_RS31380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CP969_RS31390	COG1940	carbohydrate kinase activity
CP969_RS31395	COG1129	ABC transporter
CP969_RS31400	COG1172	Belongs to the binding-protein-dependent transport system permease family
CP969_RS31465	COG2223	nitrite transmembrane transporter activity
CP969_RS31475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP969_RS31485	COG0045	succinate-CoA ligase (ADP-forming) activity
CP969_RS31495	COG1012	belongs to the aldehyde dehydrogenase family
CP969_RS31505	COG0477	Major facilitator Superfamily
CP969_RS31510	COG0477	Major facilitator Superfamily
CP969_RS31515	COG1957	nucleoside hydrolase
CP969_RS31520	COG1609	Transcriptional regulator
CP969_RS31525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP969_RS31535	COG2182	Extracellular solute-binding protein
CP969_RS31540	COG1175	transmembrane transport
CP969_RS31545	COG0395	ABC-type sugar transport system, permease component
CP969_RS31550	COG2723	6-phospho-beta-galactosidase activity
CP969_RS31585	COG2801	Transposase and inactivated derivatives
CP969_RS31615	COG0714	Associated with various cellular activities
CP969_RS31620	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CP969_RS31750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP969_RS31820	COG0297	glycogen (starch) synthase activity
CP969_RS31840	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CP969_RS31850	COG3467	pyridoxamine 5'-phosphate
CP969_RS31855	COG0477	Major facilitator Superfamily
CP969_RS31865	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CP969_RS31870	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CP969_RS31870	COG1082	Xylose isomerase domain protein TIM barrel
CP969_RS31875	COG0406	alpha-ribazole phosphatase activity
CP969_RS31880	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CP969_RS31885	COG0166	Belongs to the GPI family
CP969_RS31910	COG1486	melibiose metabolic process
CP969_RS31920	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CP969_RS31970	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP969_RS31975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CP969_RS31980	COG3485	protocatechuate 3,4-dioxygenase
CP969_RS31985	COG3485	protocatechuate 3,4-dioxygenase
CP969_RS32045	COG0789	Transcriptional regulator
CP969_RS32060	COG1834	amidinotransferase
CP969_RS32065	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CP969_RS32070	COG0488	(ABC) transporter
CP969_RS32095	COG1515	deoxyribonuclease V activity
CP969_RS32105	COG3268	Saccharopine dehydrogenase
CP969_RS32115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CP969_RS32120	COG0183	Belongs to the thiolase family
CP969_RS32125	COG1250	3-hydroxyacyl-CoA dehydrogenase
CP969_RS32125	COG1024	Enoyl-CoA hydratase
CP969_RS32145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CP969_RS32160	COG0488	(ABC) transporter
CP969_RS32165	COG2183	response to ionizing radiation
CP969_RS32170	COG4977	sequence-specific DNA binding
CP969_RS32180	COG1024	Enoyl-CoA hydratase
CP969_RS32190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CP969_RS32195	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CP969_RS32240	COG1134	teichoic acid transport
CP969_RS32245	COG1562	ergosterol biosynthetic process
CP969_RS32255	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CP969_RS32265	COG1657	PFAM Prenyltransferase squalene oxidase
CP969_RS32280	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CP969_RS32285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CP969_RS32305	COG2365	Tyrosine phosphatase family
CP969_RS32315	COG0739	heme binding
CP969_RS32320	COG2755	lipolytic protein G-D-S-L family
CP969_RS32335	COG3387	PFAM Glycoside hydrolase 15-related
CP969_RS32340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CP969_RS32375	COG1063	alcohol dehydrogenase
CP969_RS32380	COG0156	8-amino-7-oxononanoate synthase activity
CP969_RS32385	COG0583	DNA-binding transcription factor activity
CP969_RS32395	COG3958	Transketolase
CP969_RS32400	COG3959	Transketolase, thiamine diphosphate binding domain
CP969_RS32440	COG0174	glutamine synthetase
CP969_RS32465	COG0183	Belongs to the thiolase family
CP969_RS32535	COG2188	Transcriptional regulator
CP969_RS32540	COG3962	Belongs to the TPP enzyme family
CP969_RS32545	COG3718	enzyme involved in inositol metabolism
CP969_RS32555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CP969_RS32580	COG0673	inositol 2-dehydrogenase activity
CP969_RS32585	COG0673	inositol 2-dehydrogenase activity
CP969_RS32590	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS32605	COG3548	integral membrane protein
CP969_RS32610	COG0673	inositol 2-dehydrogenase activity
CP969_RS32615	COG1609	Transcriptional regulator
CP969_RS32625	COG0579	oxidoreductase
CP969_RS32640	COG2197	response regulator
CP969_RS32670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CP969_RS32680	COG2838	Isocitrate dehydrogenase
CP969_RS32685	COG0668	transmembrane transport
CP969_RS32690	COG1132	(ABC) transporter
CP969_RS32695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP969_RS32695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CP969_RS32705	COG2197	response regulator
CP969_RS32710	COG3851	Histidine kinase
CP969_RS32740	COG2268	Band 7 protein
CP969_RS32775	COG0243	molybdopterin cofactor binding
CP969_RS32785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CP969_RS32790	COG1595	DNA-templated transcription, initiation
CP969_RS32800	COG2264	protein methyltransferase activity
CP969_RS32830	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS32860	COG2378	regulation of single-species biofilm formation
CP969_RS32895	COG0514	ATP-dependent DNA helicase (RecQ)
CP969_RS32915	COG3693	PFAM glycoside hydrolase, family 10
CP969_RS32930	COG0745	RESPONSE REGULATOR receiver
CP969_RS32940	COG3321	synthase
CP969_RS32940	COG1028	Short-chain dehydrogenase reductase Sdr
CP969_RS32940	COG0604	alcohol dehydrogenase
CP969_RS32955	COG0318	PFAM AMP-dependent synthetase and ligase
CP969_RS32990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP969_RS32995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CP969_RS33000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity