locus-tag	class	description
SXIN_RS00105	COG0492	ferredoxin-NADP+ reductase activity
SXIN_RS00190	COG1864	DNA RNA non-specific endonuclease
SXIN_RS00190	COG3591	Belongs to the peptidase S1B family
SXIN_RS00225	COG0596	Alpha beta hydrolase
SXIN_RS00250	COG0583	DNA-binding transcription factor activity
SXIN_RS00270	COG2208	phosphoserine phosphatase activity
SXIN_RS00270	COG2770	Histidine kinase
SXIN_RS00280	COG3842	ATPase activity
SXIN_RS00290	COG1840	ABC-type Fe3 transport system, periplasmic component
SXIN_RS00295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SXIN_RS00330	COG0367	asparagine synthase
SXIN_RS00365	COG1007	ATP synthesis coupled electron transport
SXIN_RS00370	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SXIN_RS00375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SXIN_RS00380	COG0713	ATP synthesis coupled electron transport
SXIN_RS00390	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SXIN_RS00400	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SXIN_RS00430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SXIN_RS00440	COG0640	Transcriptional regulator
SXIN_RS00460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SXIN_RS00480	COG2076	Multidrug Resistance protein
SXIN_RS00505	COG1309	transcriptional regulator
SXIN_RS00525	COG0702	epimerase
SXIN_RS00530	COG0667	Aldo Keto reductase
SXIN_RS00560	COG2226	methyltransferase
SXIN_RS00620	COG0071	Belongs to the small heat shock protein (HSP20) family
SXIN_RS00625	COG4948	Mandelate Racemase Muconate Lactonizing
SXIN_RS00630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SXIN_RS00640	COG1414	Transcriptional regulator
SXIN_RS00665	COG1122	ATPase activity
SXIN_RS00675	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
SXIN_RS00680	COG0310	cobalt ion transport
SXIN_RS00700	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SXIN_RS00725	COG0745	RESPONSE REGULATOR receiver
SXIN_RS00730	COG5002	protein histidine kinase activity
SXIN_RS00740	COG0701	Predicted permease
SXIN_RS00755	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS00765	COG0242	peptide deformylase activity
SXIN_RS00775	COG3442	glutamine amidotransferase
SXIN_RS00780	COG0205	6-phosphofructokinase activity
SXIN_RS00840	COG0204	Acyl-transferase
SXIN_RS00850	COG0740	serine-type endopeptidase activity
SXIN_RS00870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SXIN_RS00875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SXIN_RS00880	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SXIN_RS00895	COG0577	efflux transmembrane transporter activity
SXIN_RS00895	COG1136	(ABC) transporter
SXIN_RS00920	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SXIN_RS00940	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS00945	COG1595	DNA-templated transcription, initiation
SXIN_RS00965	COG0626	cystathionine gamma-synthase activity
SXIN_RS00990	COG0419	ATPase involved in DNA repair
SXIN_RS00995	COG0420	3'-5' exonuclease activity
SXIN_RS01000	COG2376	Dihydroxyacetone kinase
SXIN_RS01005	COG1461	Dihydroxyacetone kinase
SXIN_RS01010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SXIN_RS01015	COG1739	Uncharacterized protein family UPF0029
SXIN_RS01020	COG1832	CoA-binding protein
SXIN_RS01035	COG0110	maltose O-acetyltransferase activity
SXIN_RS01065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SXIN_RS01075	COG1968	undecaprenyl-diphosphatase activity
SXIN_RS01130	COG0542	response to heat
SXIN_RS01140	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SXIN_RS01165	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SXIN_RS01210	COG0697	spore germination
SXIN_RS01245	COG0384	phenazine biosynthesis protein PhzF
SXIN_RS01270	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SXIN_RS01270	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SXIN_RS01280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SXIN_RS01300	COG1716	ATPase activity
SXIN_RS01320	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SXIN_RS01345	COG2190	(PTS) system
SXIN_RS01350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SXIN_RS01360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SXIN_RS01375	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SXIN_RS01400	COG1140	nitrate reductase beta subunit
SXIN_RS01440	COG0535	radical SAM domain protein
SXIN_RS01450	COG1140	nitrate reductase beta subunit
SXIN_RS01455	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SXIN_RS01460	COG2181	nitrate reductase activity
SXIN_RS01490	COG0516	GMP reductase activity
SXIN_RS01490	COG0517	IMP dehydrogenase activity
SXIN_RS01515	COG2018	Roadblock/LC7 domain
SXIN_RS01565	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SXIN_RS01570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SXIN_RS01575	COG1984	allophanate hydrolase subunit 2
SXIN_RS01610	COG0259	pyridoxamine-phosphate oxidase activity
SXIN_RS01635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SXIN_RS01655	COG0515	serine threonine protein kinase
SXIN_RS01675	COG2376	Dihydroxyacetone kinase
SXIN_RS01700	COG0298	carbon dioxide binding
SXIN_RS01715	COG0543	2 iron, 2 sulfur cluster binding
SXIN_RS01735	COG0309	Hydrogenase expression formation protein (HypE)
SXIN_RS01765	COG0745	RESPONSE REGULATOR receiver
SXIN_RS01795	COG0438	transferase activity, transferring glycosyl groups
SXIN_RS01905	COG2205	protein histidine kinase activity
SXIN_RS01910	COG0745	RESPONSE REGULATOR receiver
SXIN_RS01925	COG2838	Isocitrate dehydrogenase
SXIN_RS01955	COG1131	(ABC) transporter
SXIN_RS01965	COG0745	RESPONSE REGULATOR receiver
SXIN_RS01970	COG2205	protein histidine kinase activity
SXIN_RS02005	COG2770	Histidine kinase
SXIN_RS02005	COG2208	phosphoserine phosphatase activity
SXIN_RS02025	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS02045	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS02065	COG1215	transferase activity, transferring glycosyl groups
SXIN_RS02080	COG3217	Mosc domain protein beta barrel domain protein
SXIN_RS02080	COG0633	Ferredoxin
SXIN_RS02095	COG1349	DNA-binding transcription factor activity
SXIN_RS02100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SXIN_RS02115	COG1940	carbohydrate kinase activity
SXIN_RS02120	COG2223	nitrite transmembrane transporter activity
SXIN_RS02150	COG0477	Major facilitator Superfamily
SXIN_RS02160	COG2318	DinB family
SXIN_RS02165	COG0445	tRNA wobble uridine modification
SXIN_RS02185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SXIN_RS02190	COG1660	Displays ATPase and GTPase activities
SXIN_RS02205	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SXIN_RS02210	COG2086	electron transfer activity
SXIN_RS02250	COG0584	glycerophosphoryl diester phosphodiesterase
SXIN_RS02275	COG0671	phosphoesterase, PA-phosphatase related
SXIN_RS02285	COG1309	transcriptional regulator
SXIN_RS02300	COG0640	Transcriptional regulator
SXIN_RS02305	COG1902	pentaerythritol trinitrate reductase activity
SXIN_RS02315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SXIN_RS02335	COG3467	pyridoxamine 5'-phosphate
SXIN_RS02340	COG0577	efflux transmembrane transporter activity
SXIN_RS02340	COG1136	(ABC) transporter
SXIN_RS02345	COG1136	(ABC) transporter
SXIN_RS02345	COG0577	efflux transmembrane transporter activity
SXIN_RS02385	COG1809	phosphosulfolactate synthase activity
SXIN_RS02390	COG0318	PFAM AMP-dependent synthetase and ligase
SXIN_RS02395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SXIN_RS02395	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SXIN_RS02405	COG2124	cytochrome p450
SXIN_RS02410	COG2124	cytochrome p450
SXIN_RS02420	COG0475	glutathione-regulated potassium exporter activity
SXIN_RS02430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SXIN_RS02445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SXIN_RS02450	COG1132	(ABC) transporter
SXIN_RS02465	COG0745	RESPONSE REGULATOR receiver
SXIN_RS02470	COG2205	protein histidine kinase activity
SXIN_RS02475	COG1522	sequence-specific DNA binding
SXIN_RS02490	COG2226	methyltransferase
SXIN_RS02500	COG4981	capsule polysaccharide biosynthetic process
SXIN_RS02530	COG0432	Pfam Uncharacterised protein family UPF0047
SXIN_RS02535	COG2072	flavoprotein involved in K transport
SXIN_RS02540	COG1132	(ABC) transporter
SXIN_RS02555	COG1132	(ABC) transporter
SXIN_RS02570	COG1946	Acyl-CoA thioesterase
SXIN_RS02580	COG2018	Roadblock/LC7 domain
SXIN_RS02620	COG1070	Carbohydrate kinase
SXIN_RS02625	COG1940	carbohydrate kinase activity
SXIN_RS02640	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SXIN_RS02645	COG3485	protocatechuate 3,4-dioxygenase
SXIN_RS02650	COG3485	protocatechuate 3,4-dioxygenase
SXIN_RS02655	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SXIN_RS02660	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SXIN_RS02665	COG1414	Transcriptional regulator
SXIN_RS02680	COG1012	belongs to the aldehyde dehydrogenase family
SXIN_RS02705	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS02715	COG0477	Major facilitator Superfamily
SXIN_RS02725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SXIN_RS02730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SXIN_RS02795	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS02800	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS02825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SXIN_RS02830	COG0121	glutamine amidotransferase
SXIN_RS02835	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SXIN_RS02860	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SXIN_RS02865	COG1116	anion transmembrane transporter activity
SXIN_RS02870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SXIN_RS02875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SXIN_RS02885	COG3360	Dodecin
SXIN_RS02890	COG1077	Cell shape determining protein MreB Mrl
SXIN_RS02905	COG5001	Diguanylate cyclase
SXIN_RS02930	COG0745	RESPONSE REGULATOR receiver
SXIN_RS02935	COG2205	protein histidine kinase activity
SXIN_RS02940	COG2340	Cysteine-rich secretory protein family
SXIN_RS02980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SXIN_RS02985	COG3959	Transketolase, thiamine diphosphate binding domain
SXIN_RS02995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SXIN_RS02995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SXIN_RS03025	COG0437	4 iron, 4 sulfur cluster binding
SXIN_RS03095	COG0739	heme binding
SXIN_RS03095	COG1196	nuclear chromosome segregation
SXIN_RS03095	COG0741	lytic transglycosylase activity
SXIN_RS03165	COG0300	oxidoreductase activity
SXIN_RS03185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SXIN_RS03230	COG1175	transmembrane transport
SXIN_RS03235	COG0395	ABC-type sugar transport system, permease component
SXIN_RS03280	COG1404	Belongs to the peptidase S8 family
SXIN_RS03300	COG2197	response regulator
SXIN_RS03310	COG2205	protein histidine kinase activity
SXIN_RS03315	COG0745	RESPONSE REGULATOR receiver
SXIN_RS03330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SXIN_RS03350	COG3135	benzoate transporter
SXIN_RS03360	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS03440	COG4214	carbohydrate transport
SXIN_RS03450	COG4213	ABC transporter substrate-binding protein
SXIN_RS03460	COG0640	Transcriptional regulator
SXIN_RS03475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SXIN_RS03485	COG0702	epimerase
SXIN_RS03490	COG1733	regulation of RNA biosynthetic process
SXIN_RS03500	COG3711	transcriptional antiterminator
SXIN_RS03505	COG2190	(PTS) system
SXIN_RS03505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SXIN_RS03505	COG1263	PTS System
SXIN_RS03520	COG2814	Major facilitator Superfamily
SXIN_RS03565	COG2197	response regulator
SXIN_RS03580	COG2197	response regulator
SXIN_RS03590	COG0577	efflux transmembrane transporter activity
SXIN_RS03595	COG0577	efflux transmembrane transporter activity
SXIN_RS03595	COG1136	(ABC) transporter
SXIN_RS03605	COG2205	protein histidine kinase activity
SXIN_RS03610	COG0745	RESPONSE REGULATOR receiver
SXIN_RS03615	COG1408	metallophosphoesterase
SXIN_RS03625	COG0129	dihydroxy-acid dehydratase activity
SXIN_RS03635	COG1472	Belongs to the glycosyl hydrolase 3 family
SXIN_RS03645	COG1175	transmembrane transport
SXIN_RS03655	COG1609	Transcriptional regulator
SXIN_RS03760	COG4689	acetoacetate decarboxylase
SXIN_RS03780	COG1129	ABC transporter
SXIN_RS03795	COG0022	dehydrogenase e1 component
SXIN_RS03800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SXIN_RS03805	COG0604	alcohol dehydrogenase
SXIN_RS03815	COG1414	Transcriptional regulator
SXIN_RS03820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SXIN_RS03825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SXIN_RS03870	COG0406	alpha-ribazole phosphatase activity
SXIN_RS03885	COG1132	(ABC) transporter
SXIN_RS03890	COG1132	(ABC) transporter
SXIN_RS03940	COG1268	BioY protein
SXIN_RS03945	COG1984	allophanate hydrolase subunit 2
SXIN_RS03955	COG0439	Biotin carboxylase
SXIN_RS03975	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS03980	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS03995	COG0252	asparaginase activity
SXIN_RS04015	COG4608	Belongs to the ABC transporter superfamily
SXIN_RS04025	COG0601	transmembrane transport
SXIN_RS04030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SXIN_RS04040	COG0006	proline dipeptidase activity
SXIN_RS04045	COG1802	Transcriptional regulator
SXIN_RS04060	COG3938	Belongs to the proline racemase family
SXIN_RS04065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SXIN_RS04070	COG3291	Pkd domain containing protein
SXIN_RS04090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SXIN_RS04090	COG0446	pyridine nucleotide-disulphide oxidoreductase
SXIN_RS04100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SXIN_RS04105	COG3938	Belongs to the proline racemase family
SXIN_RS04115	COG0559	Belongs to the binding-protein-dependent transport system permease family
SXIN_RS04135	COG3938	Belongs to the proline racemase family
SXIN_RS04195	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
SXIN_RS04195	COG0028	Belongs to the TPP enzyme family
SXIN_RS04250	COG2801	Transposase and inactivated derivatives
SXIN_RS04265	COG2189	Belongs to the N(4) N(6)-methyltransferase family
SXIN_RS04350	COG1228	amidohydrolase
SXIN_RS04410	COG1657	PFAM Prenyltransferase squalene oxidase
SXIN_RS04420	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SXIN_RS04430	COG1562	ergosterol biosynthetic process
SXIN_RS04440	COG2409	Drug exporters of the RND superfamily
SXIN_RS04445	COG1134	teichoic acid transport
SXIN_RS04485	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SXIN_RS04495	COG1024	Enoyl-CoA hydratase
SXIN_RS04505	COG2183	response to ionizing radiation
SXIN_RS04515	COG0488	(ABC) transporter
SXIN_RS04520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SXIN_RS04535	COG0789	Transcriptional regulator
SXIN_RS04550	COG1250	3-hydroxyacyl-CoA dehydrogenase
SXIN_RS04550	COG1024	Enoyl-CoA hydratase
SXIN_RS04555	COG0183	Belongs to the thiolase family
SXIN_RS04560	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS04565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SXIN_RS04575	COG1515	deoxyribonuclease V activity
SXIN_RS04585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SXIN_RS04585	COG0723	plastoquinol--plastocyanin reductase activity
SXIN_RS04590	COG2890	protein-(glutamine-N5) methyltransferase activity
SXIN_RS04615	COG0488	(ABC) transporter
SXIN_RS04665	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SXIN_RS04700	COG5297	Belongs to the glycosyl hydrolase family 6
SXIN_RS04700	COG4733	cellulase activity
SXIN_RS04720	COG5297	Belongs to the glycosyl hydrolase family 6
SXIN_RS04730	COG0395	ABC-type sugar transport system, permease component
SXIN_RS04735	COG1175	transmembrane transport
SXIN_RS04740	COG1653	transport
SXIN_RS04745	COG0366	Alpha amylase catalytic
SXIN_RS04750	COG1653	transport
SXIN_RS04760	COG0577	efflux transmembrane transporter activity
SXIN_RS04760	COG1136	(ABC) transporter
SXIN_RS04770	COG1414	Transcriptional regulator
SXIN_RS04810	COG0667	Aldo Keto reductase
SXIN_RS04825	COG0494	nUDIX hydrolase
SXIN_RS04845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SXIN_RS04855	COG2124	cytochrome p450
SXIN_RS04860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SXIN_RS04870	COG0366	Alpha amylase catalytic
SXIN_RS04870	COG1874	Beta-galactosidase
SXIN_RS04900	COG0702	epimerase
SXIN_RS04995	COG0583	DNA-binding transcription factor activity
SXIN_RS05005	COG3629	intracellular signal transduction
SXIN_RS05005	COG3903	Transcriptional regulator
SXIN_RS05010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SXIN_RS05035	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS05045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SXIN_RS05055	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SXIN_RS05065	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SXIN_RS05075	COG3321	synthase
SXIN_RS05075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SXIN_RS05075	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SXIN_RS05080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SXIN_RS05090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SXIN_RS05105	COG1509	lysine 2,3-aminomutase activity
SXIN_RS05120	COG4585	Histidine kinase
SXIN_RS05125	COG2197	response regulator
SXIN_RS05135	COG2814	Major facilitator Superfamily
SXIN_RS05140	COG2197	response regulator
SXIN_RS05145	COG4585	Histidine kinase
SXIN_RS05170	COG3409	Peptidoglycan-binding domain 1 protein
SXIN_RS05255	COG3507	Belongs to the glycosyl hydrolase 43 family
SXIN_RS05260	COG0181	hydroxymethylbilane synthase activity
SXIN_RS05270	COG0113	porphobilinogen synthase activity
SXIN_RS05290	COG0673	inositol 2-dehydrogenase activity
SXIN_RS05295	COG1879	ABC-type sugar transport system periplasmic component
SXIN_RS05300	COG1172	Belongs to the binding-protein-dependent transport system permease family
SXIN_RS05305	COG1129	ABC transporter
SXIN_RS05310	COG1940	carbohydrate kinase activity
SXIN_RS05320	COG3629	intracellular signal transduction
SXIN_RS05320	COG3903	Transcriptional regulator
SXIN_RS05355	COG1131	(ABC) transporter
SXIN_RS05375	COG1473	amidohydrolase
SXIN_RS05390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SXIN_RS05405	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SXIN_RS05415	COG0656	L-ascorbic acid biosynthetic process
SXIN_RS05420	COG1132	(ABC) transporter
SXIN_RS05440	COG1595	DNA-templated transcription, initiation
SXIN_RS05455	COG2154	pterin-4-alpha-carbinolamine dehydratase
SXIN_RS05475	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SXIN_RS05545	COG0516	GMP reductase activity
SXIN_RS05545	COG0517	IMP dehydrogenase activity
SXIN_RS05555	COG4106	trans-aconitate 2-methyltransferase activity
SXIN_RS05585	COG0823	Involved in the tonB-independent uptake of proteins
SXIN_RS05585	COG4946	Tricorn protease homolog
SXIN_RS05585	COG1506	peptidase
SXIN_RS05590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SXIN_RS05595	COG2362	D-Aminopeptidase
SXIN_RS05620	COG1250	3-hydroxyacyl-CoA dehydrogenase
SXIN_RS05635	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SXIN_RS05635	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SXIN_RS05640	COG2301	Belongs to the HpcH HpaI aldolase family
SXIN_RS05650	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS05655	COG0688	phosphatidylethanolamine metabolic process
SXIN_RS05665	COG1929	Belongs to the glycerate kinase type-1 family
SXIN_RS05690	COG0542	response to heat
SXIN_RS05700	COG0483	inositol monophosphate 1-phosphatase activity
SXIN_RS05705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SXIN_RS05725	COG0405	Gamma-glutamyltransferase
SXIN_RS05735	COG2936	dipeptidyl-peptidase activity
SXIN_RS05735	COG2936	dipeptidyl-peptidase activity
SXIN_RS05755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SXIN_RS05760	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SXIN_RS05770	COG1940	carbohydrate kinase activity
SXIN_RS05790	COG2188	Transcriptional regulator
SXIN_RS05800	COG0800	Aldolase
SXIN_RS05810	COG1414	Transcriptional regulator
SXIN_RS05825	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SXIN_RS05860	COG0346	lactoylglutathione lyase activity
SXIN_RS05865	COG0640	Transcriptional regulator
SXIN_RS05880	COG0477	Major facilitator Superfamily
SXIN_RS05895	COG3486	L-lysine 6-monooxygenase (NADPH) activity
SXIN_RS05910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SXIN_RS05915	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SXIN_RS05920	COG1120	ATPase activity
SXIN_RS05935	COG0318	PFAM AMP-dependent synthetase and ligase
SXIN_RS05940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SXIN_RS05945	COG2197	response regulator
SXIN_RS05950	COG3835	regulator
SXIN_RS05960	COG1802	Transcriptional regulator
SXIN_RS05985	COG1162	GTPase activity
SXIN_RS05995	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS06000	COG3284	Transcriptional regulator
SXIN_RS06025	COG0175	sulfate reduction
SXIN_RS06045	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
SXIN_RS06050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SXIN_RS06095	COG0583	DNA-binding transcription factor activity
SXIN_RS06140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SXIN_RS06175	COG1309	transcriptional regulator
SXIN_RS06180	COG2409	Drug exporters of the RND superfamily
SXIN_RS06210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SXIN_RS06215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SXIN_RS06250	COG3220	belongs to the UPF0276 family
SXIN_RS06255	COG3253	May function as heme-dependent peroxidase
SXIN_RS06260	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SXIN_RS06270	COG0446	pyridine nucleotide-disulphide oxidoreductase
SXIN_RS06280	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SXIN_RS06300	COG0183	Belongs to the thiolase family
SXIN_RS06305	COG1250	3-hydroxyacyl-CoA dehydrogenase
SXIN_RS06305	COG1024	Enoyl-CoA hydratase
SXIN_RS06310	COG1316	TRANSCRIPTIONal
SXIN_RS06315	COG0514	ATP-dependent DNA helicase (RecQ)
SXIN_RS06325	COG3634	alkyl hydroperoxide reductase activity
SXIN_RS06345	COG0531	amino acid
SXIN_RS06350	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SXIN_RS06355	COG4214	carbohydrate transport
SXIN_RS06365	COG4213	ABC transporter substrate-binding protein
SXIN_RS06370	COG1940	carbohydrate kinase activity
SXIN_RS06375	COG0395	ABC-type sugar transport system, permease component
SXIN_RS06380	COG1175	transmembrane transport
SXIN_RS06385	COG1653	transport
SXIN_RS06390	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SXIN_RS06415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SXIN_RS06480	COG3387	PFAM Glycoside hydrolase 15-related
SXIN_RS06490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SXIN_RS06495	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SXIN_RS06510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SXIN_RS06520	COG2040	homocysteine
SXIN_RS06555	COG1799	cell septum assembly
SXIN_RS06580	COG4115	mRNA cleavage
SXIN_RS06585	COG2161	toxin-antitoxin pair type II binding
SXIN_RS06590	COG0586	Pfam SNARE associated Golgi protein
SXIN_RS06605	COG2130	NADP-dependent
SXIN_RS06640	COG1881	PFAM PEBP family protein
SXIN_RS06700	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SXIN_RS06720	COG5520	Belongs to the glycosyl hydrolase 30 family
SXIN_RS06740	COG1660	Displays ATPase and GTPase activities
SXIN_RS06765	COG4941	Belongs to the sigma-70 factor family
SXIN_RS06770	COG3795	YCII-related domain
SXIN_RS06790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SXIN_RS06800	COG2197	response regulator
SXIN_RS06805	COG4585	Histidine kinase
SXIN_RS06815	COG2197	response regulator
SXIN_RS06845	COG1131	(ABC) transporter
SXIN_RS06850	COG4585	Histidine kinase
SXIN_RS06855	COG0745	RESPONSE REGULATOR receiver
SXIN_RS06860	COG5002	protein histidine kinase activity
SXIN_RS06865	COG2986	histidine ammonia-lyase
SXIN_RS06885	COG0475	glutathione-regulated potassium exporter activity
SXIN_RS06895	COG0318	PFAM AMP-dependent synthetase and ligase
SXIN_RS06900	COG0492	ferredoxin-NADP+ reductase activity
SXIN_RS06905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SXIN_RS06910	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SXIN_RS06915	COG1120	ATPase activity
SXIN_RS06920	COG2755	lipolytic protein G-D-S-L family
SXIN_RS06960	COG0515	serine threonine protein kinase
SXIN_RS06970	COG0542	response to heat
SXIN_RS07020	COG1201	RNA secondary structure unwinding
SXIN_RS07075	COG1131	(ABC) transporter
SXIN_RS07095	COG1846	Transcriptional regulator
SXIN_RS07190	COG3693	PFAM glycoside hydrolase, family 10
SXIN_RS07200	COG0726	polysaccharide deacetylase
SXIN_RS07210	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
SXIN_RS07225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SXIN_RS07230	COG0531	amino acid
SXIN_RS07235	COG0569	domain protein
SXIN_RS07270	COG0756	dUTP diphosphatase activity
SXIN_RS07295	COG2205	protein histidine kinase activity
SXIN_RS07300	COG0745	RESPONSE REGULATOR receiver
SXIN_RS07310	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SXIN_RS07340	COG1435	thymidine kinase activity
SXIN_RS07360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SXIN_RS07365	COG1802	Transcriptional regulator
SXIN_RS07380	COG0612	Peptidase, M16
SXIN_RS07400	COG0659	secondary active sulfate transmembrane transporter activity
SXIN_RS07410	COG0187	DNA topoisomerase II activity
SXIN_RS07425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SXIN_RS07430	COG1802	Transcriptional regulator
SXIN_RS07460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SXIN_RS07480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SXIN_RS07485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SXIN_RS07490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SXIN_RS07520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SXIN_RS07525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SXIN_RS07530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SXIN_RS07540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SXIN_RS07550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SXIN_RS07560	COG2205	protein histidine kinase activity
SXIN_RS07565	COG0745	RESPONSE REGULATOR receiver
SXIN_RS07570	COG1126	abc transporter atp-binding protein
SXIN_RS07575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SXIN_RS07580	COG0765	amino acid transport
SXIN_RS07585	COG0765	amino acid transport
SXIN_RS07590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SXIN_RS07600	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SXIN_RS07625	COG1201	RNA secondary structure unwinding
SXIN_RS07630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SXIN_RS07640	COG0783	Belongs to the Dps family
SXIN_RS07645	COG1396	sequence-specific DNA binding
SXIN_RS07650	COG1546	Belongs to the CinA family
SXIN_RS07650	COG1058	Belongs to the CinA family
SXIN_RS07660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SXIN_RS07670	COG1674	ftsk spoiiie
SXIN_RS07680	COG3850	Histidine kinase
SXIN_RS07680	COG4999	Histidine kinase
SXIN_RS07680	COG3437	response regulator, receiver
SXIN_RS07680	COG2205	protein histidine kinase activity
SXIN_RS07695	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SXIN_RS07720	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SXIN_RS07725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SXIN_RS07730	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SXIN_RS07745	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SXIN_RS07750	COG0612	Peptidase, M16
SXIN_RS07755	COG1185	polyribonucleotide nucleotidyltransferase activity
SXIN_RS07760	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SXIN_RS07770	COG1674	ftsk spoiiie
SXIN_RS07850	COG0455	bacterial-type flagellum organization
SXIN_RS07865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SXIN_RS07870	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SXIN_RS07880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SXIN_RS07895	COG0779	Required for maturation of 30S ribosomal subunits
SXIN_RS07915	COG0442	prolyl-tRNA aminoacylation
SXIN_RS07930	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SXIN_RS07935	COG0750	zinc metalloprotease
SXIN_RS07940	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SXIN_RS07970	COG1609	Transcriptional regulator
SXIN_RS07980	COG0318	PFAM AMP-dependent synthetase and ligase
SXIN_RS08000	COG0395	ABC-type sugar transport system, permease component
SXIN_RS08005	COG4209	transmembrane transport
SXIN_RS08015	COG1472	Belongs to the glycosyl hydrolase 3 family
SXIN_RS08050	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SXIN_RS08065	COG1012	belongs to the aldehyde dehydrogenase family
SXIN_RS08070	COG1136	(ABC) transporter
SXIN_RS08080	COG3842	ATPase activity
SXIN_RS08095	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SXIN_RS08105	COG0233	cytoplasmic translational termination
SXIN_RS08110	COG0528	UMP kinase activity
SXIN_RS08115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SXIN_RS08120	COG0052	Belongs to the universal ribosomal protein uS2 family
SXIN_RS08135	COG1191	sigma factor activity
SXIN_RS08150	COG0792	nuclease activity
SXIN_RS08170	COG0681	Belongs to the peptidase S26 family
SXIN_RS08180	COG0681	Belongs to the peptidase S26 family
SXIN_RS08185	COG0335	large ribosomal subunit rRNA binding
SXIN_RS08190	COG0336	Belongs to the RNA methyltransferase TrmD family
SXIN_RS08195	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SXIN_RS08200	COG1837	Belongs to the UPF0109 family
SXIN_RS08205	COG0228	four-way junction DNA binding
SXIN_RS08225	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SXIN_RS08255	COG0477	Major facilitator Superfamily
SXIN_RS08275	COG1254	Belongs to the acylphosphatase family
SXIN_RS08285	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SXIN_RS08290	COG0571	ribonuclease III activity
SXIN_RS08295	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SXIN_RS08310	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SXIN_RS08315	COG0742	ribosomal rna small subunit methyltransferase
SXIN_RS08330	COG1461	Dihydroxyacetone kinase
SXIN_RS08335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SXIN_RS08340	COG0351	phosphomethylpyrimidine kinase
SXIN_RS08360	COG1181	Belongs to the D-alanine--D-alanine ligase family
SXIN_RS08365	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SXIN_RS08375	COG1920	GTP binding
SXIN_RS08385	COG0776	regulation of translation
SXIN_RS08395	COG0066	3-isopropylmalate dehydratase activity
SXIN_RS08400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SXIN_RS08405	COG1414	Transcriptional regulator
SXIN_RS08435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SXIN_RS08440	COG0179	Fumarylacetoacetate (FAA) hydrolase
SXIN_RS08455	COG2018	Roadblock/LC7 domain
SXIN_RS08475	COG2018	Roadblock/LC7 domain
SXIN_RS08495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SXIN_RS08500	COG2353	YceI-like domain
SXIN_RS08505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SXIN_RS08510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SXIN_RS08515	COG0473	3-isopropylmalate dehydrogenase activity
SXIN_RS08530	COG1012	belongs to the aldehyde dehydrogenase family
SXIN_RS08535	COG0506	proline dehydrogenase activity
SXIN_RS08540	COG3835	regulator
SXIN_RS08545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SXIN_RS08550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SXIN_RS08555	COG0440	acetolactate synthase activity
SXIN_RS08575	COG0667	Aldo Keto reductase
SXIN_RS08580	COG2133	pyrroloquinoline quinone binding
SXIN_RS08585	COG1672	PFAM Archaeal ATPase
SXIN_RS08585	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SXIN_RS08595	COG2409	Drug exporters of the RND superfamily
SXIN_RS08600	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SXIN_RS08610	COG0154	amidase activity
SXIN_RS08615	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SXIN_RS08625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SXIN_RS08635	COG4221	oxidoreductase activity
SXIN_RS08675	COG0482	sulfurtransferase activity
SXIN_RS08690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SXIN_RS08715	COG2860	membrane
SXIN_RS08720	COG4608	Belongs to the ABC transporter superfamily
SXIN_RS08725	COG0444	Belongs to the ABC transporter superfamily
SXIN_RS08730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SXIN_RS08735	COG0601	transmembrane transport
SXIN_RS08740	COG0747	negative chemotaxis
SXIN_RS08760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SXIN_RS08765	COG0509	glycine decarboxylation via glycine cleavage system
SXIN_RS08770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SXIN_RS08775	COG1760	l-serine dehydratase
SXIN_RS08805	COG3903	Transcriptional regulator
SXIN_RS08805	COG3629	intracellular signal transduction
SXIN_RS08815	COG0513	Belongs to the DEAD box helicase family
SXIN_RS08820	COG1278	Cold shock
SXIN_RS08835	COG1024	Enoyl-CoA hydratase
SXIN_RS08840	COG1376	ErfK ybiS ycfS ynhG family protein
SXIN_RS08850	COG1132	(ABC) transporter
SXIN_RS08855	COG1132	(ABC) transporter
SXIN_RS08865	COG0058	SHG alpha-glucan phosphorylase activity
SXIN_RS08870	COG3401	FG-GAP repeat protein
SXIN_RS08880	COG0366	Alpha amylase catalytic
SXIN_RS08895	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SXIN_RS08900	COG1301	dicarboxylic acid transport
SXIN_RS08905	COG3290	protein histidine kinase activity
SXIN_RS08910	COG4565	transcriptional regulatory protein
SXIN_RS08920	COG0205	6-phosphofructokinase activity
SXIN_RS08925	COG0857	belongs to the CobB CobQ family
SXIN_RS08925	COG0280	phosphate acetyltransferase
SXIN_RS08930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SXIN_RS08965	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SXIN_RS08965	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SXIN_RS09010	COG0642	Histidine kinase
SXIN_RS09010	COG3850	Histidine kinase
SXIN_RS09015	COG0745	RESPONSE REGULATOR receiver
SXIN_RS09030	COG0183	Belongs to the thiolase family
SXIN_RS09035	COG0346	lactoylglutathione lyase activity
SXIN_RS09075	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SXIN_RS09105	COG2197	response regulator
SXIN_RS09115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SXIN_RS09120	COG0318	PFAM AMP-dependent synthetase and ligase
SXIN_RS09125	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS09135	COG0515	serine threonine protein kinase
SXIN_RS09145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SXIN_RS09155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SXIN_RS09165	COG0028	Belongs to the TPP enzyme family
SXIN_RS09190	COG2197	response regulator
SXIN_RS09200	COG2197	response regulator
SXIN_RS09215	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SXIN_RS09220	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SXIN_RS09225	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SXIN_RS09230	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SXIN_RS09235	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SXIN_RS09240	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SXIN_RS09245	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SXIN_RS09265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SXIN_RS09275	COG2890	protein-(glutamine-N5) methyltransferase activity
SXIN_RS09280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SXIN_RS09285	COG0254	rRNA binding
SXIN_RS09290	COG1316	TRANSCRIPTIONal
SXIN_RS09300	COG0083	homoserine kinase activity
SXIN_RS09305	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SXIN_RS09310	COG0460	homoserine dehydrogenase
SXIN_RS09315	COG0019	diaminopimelate decarboxylase activity
SXIN_RS09320	COG0018	arginyl-trna synthetase
SXIN_RS09430	COG0277	FAD linked oxidase domain protein
SXIN_RS09430	COG0247	lactate metabolic process
SXIN_RS09435	COG4948	Mandelate Racemase Muconate Lactonizing
SXIN_RS09465	COG0628	permease
SXIN_RS09470	COG3383	formate dehydrogenase (NAD+) activity
SXIN_RS09470	COG0243	molybdopterin cofactor binding
SXIN_RS09475	COG0243	molybdopterin cofactor binding
SXIN_RS09475	COG3383	formate dehydrogenase (NAD+) activity
SXIN_RS09480	COG0709	Synthesizes selenophosphate from selenide and ATP
SXIN_RS09500	COG0702	epimerase
SXIN_RS09545	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SXIN_RS09575	COG0772	Belongs to the SEDS family
SXIN_RS09580	COG0768	penicillin binding
SXIN_RS09600	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SXIN_RS09675	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SXIN_RS09680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SXIN_RS09705	COG1595	DNA-templated transcription, initiation
SXIN_RS09715	COG1131	(ABC) transporter
SXIN_RS09730	COG0745	RESPONSE REGULATOR receiver
SXIN_RS09735	COG2205	protein histidine kinase activity
SXIN_RS09740	COG0567	Dehydrogenase, E1 component
SXIN_RS09740	COG0508	dehydrogenase complex catalyzes the overall conversion of
SXIN_RS09760	COG0604	alcohol dehydrogenase
SXIN_RS09765	COG0281	malic enzyme
SXIN_RS09775	COG0765	amino acid transport
SXIN_RS09780	COG1126	abc transporter atp-binding protein
SXIN_RS09800	COG0456	acetyltransferase
SXIN_RS09810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SXIN_RS09825	COG2172	sigma factor antagonist activity
SXIN_RS09840	COG1597	lipid kinase activity
SXIN_RS09855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SXIN_RS09860	COG2188	Transcriptional regulator
SXIN_RS09865	COG1966	Carbon starvation protein
SXIN_RS09880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SXIN_RS09900	COG0242	peptide deformylase activity
SXIN_RS09910	COG2199	diguanylate cyclase activity
SXIN_RS09910	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SXIN_RS09915	COG2199	diguanylate cyclase activity
SXIN_RS09915	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SXIN_RS09920	COG5662	AntiSigma factor
SXIN_RS09925	COG1595	DNA-templated transcription, initiation
SXIN_RS09935	COG2135	peptidase activity
SXIN_RS09945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SXIN_RS09960	COG0483	inositol monophosphate 1-phosphatase activity
SXIN_RS09970	COG0753	catalase activity
SXIN_RS09995	COG1615	UPF0182 protein
SXIN_RS10005	COG3480	Lon protease (S16) C-terminal proteolytic domain
SXIN_RS10060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SXIN_RS10185	COG0513	Belongs to the DEAD box helicase family
SXIN_RS10195	COG1432	Conserved Protein
SXIN_RS10205	COG2095	MarC family integral membrane protein
SXIN_RS10225	COG0598	Magnesium transport protein CorA
SXIN_RS10260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SXIN_RS10265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SXIN_RS10275	COG1595	DNA-templated transcription, initiation
SXIN_RS10290	COG1024	Enoyl-CoA hydratase
SXIN_RS10295	COG0519	Catalyzes the synthesis of GMP from XMP
SXIN_RS10305	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SXIN_RS10310	COG1611	Belongs to the LOG family
SXIN_RS10315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SXIN_RS10345	COG2912	Transglutaminase-like superfamily
SXIN_RS10360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SXIN_RS10375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SXIN_RS10380	COG0747	negative chemotaxis
SXIN_RS10385	COG0601	transmembrane transport
SXIN_RS10395	COG4608	Belongs to the ABC transporter superfamily
SXIN_RS10400	COG4608	Belongs to the ABC transporter superfamily
SXIN_RS10410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SXIN_RS10415	COG0601	transmembrane transport
SXIN_RS10420	COG4166	transmembrane transport
SXIN_RS10435	COG4608	Belongs to the ABC transporter superfamily
SXIN_RS10440	COG0444	Belongs to the ABC transporter superfamily
SXIN_RS10445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SXIN_RS10450	COG0601	transmembrane transport
SXIN_RS10460	COG1217	gtp-binding protein TYPA
SXIN_RS10480	COG1053	succinate dehydrogenase
SXIN_RS10560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SXIN_RS10575	COG3842	ATPase activity
SXIN_RS10585	COG1177	transmembrane transport
SXIN_RS10590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SXIN_RS10600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SXIN_RS10625	COG1131	(ABC) transporter
SXIN_RS10635	COG1595	DNA-templated transcription, initiation
SXIN_RS10695	COG0012	GTP binding
SXIN_RS10710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SXIN_RS10715	COG1570	exodeoxyribonuclease VII activity
SXIN_RS10720	COG1722	exodeoxyribonuclease VII activity
SXIN_RS10725	COG0778	Nitroreductase
SXIN_RS10750	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
SXIN_RS10750	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
SXIN_RS10755	COG0114	fumarate hydratase activity
SXIN_RS10775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SXIN_RS10825	COG1136	(ABC) transporter
SXIN_RS10840	COG0450	alkyl hydroperoxide reductase
SXIN_RS10845	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SXIN_RS10860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SXIN_RS10865	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SXIN_RS10870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SXIN_RS10875	COG0667	Aldo Keto reductase
SXIN_RS10900	COG2885	chlorophyll binding
SXIN_RS10950	COG2894	cell division
SXIN_RS10995	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SXIN_RS11005	COG1331	Highly conserved protein containing a thioredoxin domain
SXIN_RS11030	COG1331	Highly conserved protein containing a thioredoxin domain
SXIN_RS11040	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SXIN_RS11055	COG1331	Highly conserved protein containing a thioredoxin domain
SXIN_RS11070	COG4974	Belongs to the 'phage' integrase family
SXIN_RS11100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SXIN_RS11110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SXIN_RS11125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SXIN_RS11130	COG2255	four-way junction helicase activity
SXIN_RS11160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SXIN_RS11165	COG2318	DinB family
SXIN_RS11180	COG3397	chitin binding
SXIN_RS11240	COG1136	(ABC) transporter
SXIN_RS11260	COG2986	histidine ammonia-lyase
SXIN_RS11265	COG1024	Enoyl-CoA hydratase
SXIN_RS11275	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SXIN_RS11285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SXIN_RS11295	COG0424	maF-like protein
SXIN_RS11305	COG4770	biotin carboxylase activity
SXIN_RS11315	COG1349	DNA-binding transcription factor activity
SXIN_RS11335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SXIN_RS11345	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SXIN_RS11350	COG1012	belongs to the aldehyde dehydrogenase family
SXIN_RS11355	COG1012	belongs to the aldehyde dehydrogenase family
SXIN_RS11365	COG1595	DNA-templated transcription, initiation
SXIN_RS11370	COG0745	RESPONSE REGULATOR receiver
SXIN_RS11375	COG2205	protein histidine kinase activity
SXIN_RS11400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SXIN_RS11410	COG0583	DNA-binding transcription factor activity
SXIN_RS11415	COG2814	Major facilitator Superfamily
SXIN_RS11435	COG1079	Belongs to the binding-protein-dependent transport system permease family
SXIN_RS11440	COG1079	Belongs to the binding-protein-dependent transport system permease family
SXIN_RS11445	COG3845	ABC transporter
SXIN_RS11450	COG1744	ABC transporter substrate-binding protein PnrA-like
SXIN_RS11455	COG1473	amidohydrolase
SXIN_RS11455	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SXIN_RS11465	COG2089	acid synthase
SXIN_RS11470	COG1083	cytidylyl-transferase
SXIN_RS11480	COG1216	Glycosyl transferase, family 2
SXIN_RS11490	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SXIN_RS11525	COG2610	gluconate transmembrane transporter activity
SXIN_RS11530	COG3265	gluconokinase activity
SXIN_RS11535	COG2186	Transcriptional regulator
SXIN_RS11550	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SXIN_RS11550	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SXIN_RS11560	COG1595	DNA-templated transcription, initiation
SXIN_RS11570	COG1595	DNA-templated transcription, initiation
SXIN_RS11595	COG2009	succinate dehydrogenase
SXIN_RS11610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SXIN_RS11615	COG0747	negative chemotaxis
SXIN_RS11620	COG1408	metallophosphoesterase
SXIN_RS11630	COG1686	Belongs to the peptidase S11 family
SXIN_RS11635	COG1295	ribonuclease BN
SXIN_RS11640	COG1309	transcriptional regulator
SXIN_RS11655	COG0180	Tryptophanyl-tRNA synthetase
SXIN_RS11660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SXIN_RS11665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SXIN_RS11670	COG1414	Transcriptional regulator
SXIN_RS11680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SXIN_RS11685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SXIN_RS11695	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SXIN_RS11705	COG4176	ABC-type proline glycine betaine transport system permease component
SXIN_RS11710	COG4175	Glycine betaine
SXIN_RS11710	COG0517	IMP dehydrogenase activity
SXIN_RS11720	COG1012	belongs to the aldehyde dehydrogenase family
SXIN_RS11725	COG0039	L-malate dehydrogenase activity
SXIN_RS11750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SXIN_RS11755	COG0138	bifunctional purine biosynthesis protein purh
SXIN_RS11780	COG0045	succinate-CoA ligase (ADP-forming) activity
SXIN_RS11810	COG1222	aaa ATPase
SXIN_RS11895	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SXIN_RS11905	COG0714	Associated with various cellular activities
SXIN_RS11925	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SXIN_RS11925	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SXIN_RS11935	COG0739	heme binding
SXIN_RS11955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SXIN_RS11970	COG1104	cysteine desulfurase activity
SXIN_RS12010	COG2197	response regulator
SXIN_RS12040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SXIN_RS12040	COG0519	Catalyzes the synthesis of GMP from XMP
SXIN_RS12070	COG1012	belongs to the aldehyde dehydrogenase family
SXIN_RS12090	COG0515	serine threonine protein kinase
SXIN_RS12105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SXIN_RS12120	COG0516	GMP reductase activity
SXIN_RS12130	COG1595	DNA-templated transcription, initiation
SXIN_RS12150	COG4221	oxidoreductase activity
SXIN_RS12160	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SXIN_RS12170	COG0726	polysaccharide deacetylase
SXIN_RS12190	COG1556	Lactate utilization protein
SXIN_RS12195	COG1139	Iron-sulfur cluster binding protein
SXIN_RS12200	COG0247	lactate metabolic process
SXIN_RS12205	COG1620	l-lactate permease
SXIN_RS12210	COG2186	Transcriptional regulator
SXIN_RS12220	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SXIN_RS12255	COG0802	atpase or kinase
SXIN_RS12265	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SXIN_RS12290	COG0736	holo-[acyl-carrier-protein] synthase activity
SXIN_RS12295	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SXIN_RS12305	COG1072	(Pantothenic acid kinase))
SXIN_RS12315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SXIN_RS12320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SXIN_RS12325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SXIN_RS12330	COG0583	DNA-binding transcription factor activity
SXIN_RS12340	COG0488	(ABC) transporter
SXIN_RS12365	COG0101	tRNA pseudouridine synthase activity
SXIN_RS12370	COG0203	ribosomal protein L17
SXIN_RS12375	COG0202	RNA polymerase activity
SXIN_RS12380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SXIN_RS12385	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SXIN_RS12390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SXIN_RS12395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SXIN_RS12400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SXIN_RS12410	COG0563	adenylate kinase activity
SXIN_RS12415	COG0201	protein transport
SXIN_RS12420	COG0200	Binds to the 23S rRNA
SXIN_RS12430	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SXIN_RS12435	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SXIN_RS12440	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SXIN_RS12445	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SXIN_RS12455	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SXIN_RS12460	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SXIN_RS12465	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SXIN_RS12470	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SXIN_RS12475	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SXIN_RS12480	COG0255	Belongs to the universal ribosomal protein uL29 family
SXIN_RS12485	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SXIN_RS12490	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SXIN_RS12495	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SXIN_RS12500	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SXIN_RS12505	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SXIN_RS12510	COG0089	rRNA binding
SXIN_RS12515	COG0088	Forms part of the polypeptide exit tunnel
SXIN_RS12520	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SXIN_RS12525	COG0051	transcription antitermination factor activity, RNA binding
SXIN_RS12535	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SXIN_RS12555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SXIN_RS12560	COG0049	tRNA binding
SXIN_RS12565	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SXIN_RS12575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SXIN_RS12580	COG0085	RNA polymerase activity
SXIN_RS12590	COG0222	ribosome binding
SXIN_RS12595	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SXIN_RS12600	COG0081	regulation of translation
SXIN_RS12605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SXIN_RS12625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SXIN_RS12630	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SXIN_RS12640	COG2030	dehydratase
SXIN_RS12645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SXIN_RS12665	COG0702	epimerase
SXIN_RS12675	COG1666	GTP binding
SXIN_RS12690	COG3304	Inner membrane component domain
SXIN_RS12700	COG0501	Belongs to the peptidase M48B family
SXIN_RS12705	COG1007	ATP synthesis coupled electron transport
SXIN_RS12720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SXIN_RS12725	COG0713	ATP synthesis coupled electron transport
SXIN_RS12730	COG0839	Belongs to the complex I subunit 6 family
SXIN_RS12735	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SXIN_RS12740	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SXIN_RS12745	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SXIN_RS12750	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SXIN_RS12755	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SXIN_RS12760	COG4585	Histidine kinase
SXIN_RS12765	COG4585	Histidine kinase
SXIN_RS12775	COG0674	pyruvate-flavodoxin oxidoreductase activity
SXIN_RS12775	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SXIN_RS12780	COG1013	pyruvate-flavodoxin oxidoreductase activity
SXIN_RS12805	COG4935	Belongs to the peptidase S8 family
SXIN_RS12805	COG2234	aminopeptidase activity
SXIN_RS12820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SXIN_RS12825	COG0446	pyridine nucleotide-disulphide oxidoreductase
SXIN_RS12845	COG0142	geranyltranstransferase activity
SXIN_RS12850	COG0492	ferredoxin-NADP+ reductase activity
SXIN_RS12875	COG1007	ATP synthesis coupled electron transport
SXIN_RS12885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SXIN_RS12890	COG0713	ATP synthesis coupled electron transport
SXIN_RS12895	COG0839	Belongs to the complex I subunit 6 family
SXIN_RS12900	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SXIN_RS12905	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SXIN_RS12910	COG1034	ATP synthesis coupled electron transport
SXIN_RS12915	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SXIN_RS12925	COG0649	NAD binding
SXIN_RS12930	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SXIN_RS12935	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SXIN_RS12945	COG0791	NLP P60 protein
SXIN_RS12955	COG2226	methyltransferase
SXIN_RS12995	COG2226	methyltransferase
SXIN_RS13010	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SXIN_RS13015	COG0515	serine threonine protein kinase
SXIN_RS13015	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SXIN_RS13020	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SXIN_RS13025	COG1278	Cold shock
SXIN_RS13035	COG0183	Belongs to the thiolase family
SXIN_RS13050	COG1309	transcriptional regulator
SXIN_RS13060	COG1301	dicarboxylic acid transport
SXIN_RS13075	COG1573	uracil-dna glycosylase
SXIN_RS13080	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SXIN_RS13090	COG0163	prenyltransferase activity
SXIN_RS13105	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SXIN_RS13115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SXIN_RS13120	COG1333	cytochrome c biogenesis protein
SXIN_RS13125	COG0785	Cytochrome C biogenesis protein
SXIN_RS13130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SXIN_RS13135	COG0406	alpha-ribazole phosphatase activity
SXIN_RS13140	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SXIN_RS13160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SXIN_RS13165	COG0475	glutathione-regulated potassium exporter activity
SXIN_RS13185	COG1690	Belongs to the RtcB family
SXIN_RS13205	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SXIN_RS13210	COG0018	arginyl-trna synthetase
SXIN_RS13230	COG0113	porphobilinogen synthase activity
SXIN_RS13235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SXIN_RS13235	COG1648	precorrin-2 dehydrogenase activity
SXIN_RS13240	COG0181	hydroxymethylbilane synthase activity
SXIN_RS13245	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SXIN_RS13250	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SXIN_RS13265	COG1595	DNA-templated transcription, initiation
SXIN_RS13300	COG0123	including yeast histone deacetylase and acetoin utilization protein
SXIN_RS13305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SXIN_RS13330	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SXIN_RS13340	COG1129	ABC transporter
SXIN_RS13340	COG0842	Transport permease protein
SXIN_RS13350	COG1252	NADH dehydrogenase
SXIN_RS13355	COG1595	DNA-templated transcription, initiation
SXIN_RS13365	COG0129	dihydroxy-acid dehydratase activity
SXIN_RS13375	COG1082	Xylose isomerase domain protein TIM barrel
SXIN_RS13380	COG0248	Ppx GppA phosphatase
SXIN_RS13400	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SXIN_RS13410	COG1194	a g-specific adenine glycosylase
SXIN_RS13415	COG1595	DNA-templated transcription, initiation
SXIN_RS13425	COG0745	RESPONSE REGULATOR receiver
SXIN_RS13430	COG2205	protein histidine kinase activity
SXIN_RS13445	COG0739	heme binding
SXIN_RS13445	COG0741	lytic transglycosylase activity
SXIN_RS13445	COG1196	nuclear chromosome segregation
SXIN_RS13480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SXIN_RS13500	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SXIN_RS13510	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SXIN_RS13515	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SXIN_RS13530	COG2197	response regulator
SXIN_RS13535	COG4585	Histidine kinase
SXIN_RS13555	COG0649	NAD binding
SXIN_RS13570	COG1174	glycine betaine transport
SXIN_RS13575	COG1174	glycine betaine transport
SXIN_RS13580	COG1125	glycine betaine transport
SXIN_RS13580	COG0517	IMP dehydrogenase activity
SXIN_RS13590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SXIN_RS13595	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SXIN_RS13610	COG0302	gtp cyclohydrolase
SXIN_RS13625	COG0037	tRNA processing
SXIN_RS13635	COG2027	D-alanyl-D-alanine carboxypeptidase
SXIN_RS13640	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SXIN_RS13650	COG0586	Pfam SNARE associated Golgi protein
SXIN_RS13655	COG0655	NAD(P)H dehydrogenase (quinone) activity
SXIN_RS13665	COG2318	DinB family
SXIN_RS13670	COG1012	belongs to the aldehyde dehydrogenase family
SXIN_RS13685	COG0542	response to heat
SXIN_RS13695	COG1793	dna ligase
SXIN_RS13730	COG4608	Belongs to the ABC transporter superfamily
SXIN_RS13735	COG0444	Belongs to the ABC transporter superfamily
SXIN_RS13740	COG0601	transmembrane transport
SXIN_RS13770	COG0142	geranyltranstransferase activity
SXIN_RS13795	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SXIN_RS13845	COG1609	Transcriptional regulator
SXIN_RS13860	COG0395	ABC-type sugar transport system, permease component
SXIN_RS13875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SXIN_RS13880	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SXIN_RS13920	COG0275	rRNA processing
SXIN_RS13925	COG0438	transferase activity, transferring glycosyl groups
SXIN_RS13945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SXIN_RS13950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SXIN_RS13970	COG0489	protein tyrosine kinase activity
SXIN_RS13980	COG4221	oxidoreductase activity
SXIN_RS13985	COG3547	Transposase (IS116 IS110 IS902 family)
SXIN_RS14025	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SXIN_RS14030	COG1754	DNA topoisomerase type I activity
SXIN_RS14030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SXIN_RS14055	COG2264	protein methyltransferase activity
SXIN_RS14065	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SXIN_RS14080	COG1366	Belongs to the anti-sigma-factor antagonist family
SXIN_RS14085	COG1111	helicase
SXIN_RS14085	COG1205	dead DEAH box helicase
SXIN_RS14150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SXIN_RS14155	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SXIN_RS14165	COG2267	carboxylic ester hydrolase activity
SXIN_RS14195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SXIN_RS14220	COG0003	Pfam Anion-transporting ATPase
SXIN_RS14235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SXIN_RS14245	COG1408	metallophosphoesterase
SXIN_RS14290	COG3547	Transposase (IS116 IS110 IS902 family)
SXIN_RS14295	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SXIN_RS14310	COG2226	methyltransferase
SXIN_RS14325	COG3851	Histidine kinase
SXIN_RS14330	COG2197	response regulator
SXIN_RS14410	COG0667	Aldo Keto reductase
SXIN_RS14475	COG0569	domain protein
SXIN_RS14480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SXIN_RS14485	COG0435	Glutathione S-transferase
SXIN_RS14490	COG1609	Transcriptional regulator
SXIN_RS14495	COG3254	rhamnose metabolic process
SXIN_RS14515	COG1129	ABC transporter
SXIN_RS14525	COG3347	Dehydrogenase
SXIN_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS14530	COG1070	Carbohydrate kinase
SXIN_RS14540	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SXIN_RS14545	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SXIN_RS14605	COG1801	Protein of unknown function DUF72
SXIN_RS14615	COG0574	Belongs to the PEP-utilizing enzyme family
SXIN_RS14615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SXIN_RS14650	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SXIN_RS14665	COG0590	tRNA wobble adenosine to inosine editing
SXIN_RS14680	COG1191	sigma factor activity
SXIN_RS14685	COG1191	sigma factor activity
SXIN_RS14700	COG0477	Major facilitator Superfamily
SXIN_RS14710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SXIN_RS14740	COG4251	negative regulation of phosphorylation
SXIN_RS14745	COG0318	PFAM AMP-dependent synthetase and ligase
SXIN_RS14750	COG1595	DNA-templated transcription, initiation
SXIN_RS14765	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SXIN_RS14770	COG2188	Transcriptional regulator
SXIN_RS14845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SXIN_RS14860	COG0653	protein targeting
SXIN_RS14870	COG0006	proline dipeptidase activity
SXIN_RS14885	COG1999	signal sequence binding
SXIN_RS14910	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SXIN_RS14915	COG0561	phosphatase activity
SXIN_RS14940	COG1131	(ABC) transporter
SXIN_RS14960	COG0561	phosphatase activity
SXIN_RS14965	COG4988	ABC transporter
SXIN_RS14970	COG1294	oxidase, subunit
SXIN_RS14975	COG1271	oxidase subunit
SXIN_RS14980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SXIN_RS14985	COG1609	Transcriptional regulator
SXIN_RS14990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SXIN_RS15000	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SXIN_RS15020	COG0662	Cupin 2, conserved barrel domain protein
SXIN_RS15025	COG1950	PFAM Membrane protein of
SXIN_RS15030	COG0626	cystathionine gamma-synthase activity
SXIN_RS15045	COG0305	Participates in initiation and elongation during chromosome replication
SXIN_RS15055	COG0359	binds to the 23S rRNA
SXIN_RS15060	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SXIN_RS15065	COG0629	single-stranded DNA binding
SXIN_RS15070	COG0360	Binds together with S18 to 16S ribosomal RNA
SXIN_RS15095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SXIN_RS15115	COG0617	tRNA 3'-terminal CCA addition
SXIN_RS15130	COG2815	serine threonine protein kinase
SXIN_RS15130	COG0515	serine threonine protein kinase
SXIN_RS15135	COG1595	DNA-templated transcription, initiation
SXIN_RS15145	COG0492	ferredoxin-NADP+ reductase activity
SXIN_RS15150	COG3118	belongs to the thioredoxin family
SXIN_RS15165	COG1192	Involved in chromosome partitioning
SXIN_RS15170	COG0357	Ribosomal RNA small subunit methyltransferase G
SXIN_RS15180	COG0706	membrane insertase activity
SXIN_RS15185	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SXIN_RS15195	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SXIN_RS15210	COG0592	DNA-directed DNA polymerase activity
SXIN_RS15215	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SXIN_RS15220	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SXIN_RS15225	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
SXIN_RS15230	COG0187	DNA topoisomerase II activity
SXIN_RS15235	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SXIN_RS15240	COG3266	domain, Protein
SXIN_RS15260	COG0515	serine threonine protein kinase
SXIN_RS15285	COG0705	Rhomboid family
SXIN_RS15310	COG3764	Sortase (surface protein transpeptidase)
SXIN_RS15315	COG3764	Sortase (surface protein transpeptidase)
SXIN_RS15320	COG0515	serine threonine protein kinase
SXIN_RS15325	COG0768	penicillin binding
SXIN_RS15340	COG1716	ATPase activity
SXIN_RS15355	COG2271	Major facilitator Superfamily
SXIN_RS15360	COG0659	secondary active sulfate transmembrane transporter activity
SXIN_RS15365	COG0789	Transcriptional regulator
SXIN_RS15370	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SXIN_RS15380	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SXIN_RS15395	COG0798	PFAM Bile acid sodium symporter
SXIN_RS15400	COG0640	Transcriptional regulator
SXIN_RS15405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SXIN_RS15410	COG2226	methyltransferase
SXIN_RS15415	COG4585	Histidine kinase
SXIN_RS15420	COG2197	response regulator
SXIN_RS15440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SXIN_RS15445	COG2151	metal-sulfur cluster biosynthetic enzyme
SXIN_RS15450	COG3396	Phenylacetate-CoA oxygenase
SXIN_RS15455	COG3460	Phenylacetate-CoA oxygenase
SXIN_RS15460	COG3396	Phenylacetate-CoA oxygenase
SXIN_RS15480	COG1486	melibiose metabolic process
SXIN_RS15495	COG1250	3-hydroxyacyl-CoA dehydrogenase
SXIN_RS15500	COG1309	transcriptional regulator
SXIN_RS15505	COG1522	sequence-specific DNA binding
SXIN_RS15530	COG0303	'Molybdopterin
SXIN_RS15535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SXIN_RS15555	COG0515	serine threonine protein kinase
SXIN_RS15560	COG0515	serine threonine protein kinase
SXIN_RS15575	COG0022	dehydrogenase e1 component
SXIN_RS15580	COG0508	dehydrogenase complex catalyzes the overall conversion of
SXIN_RS15635	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SXIN_RS15645	COG1362	aminopeptidase activity
SXIN_RS15650	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS15670	COG1741	Belongs to the pirin family
SXIN_RS15680	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SXIN_RS15695	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SXIN_RS15705	COG2268	Band 7 protein
SXIN_RS15710	COG2304	oxidoreductase activity
SXIN_RS15750	COG1131	(ABC) transporter
SXIN_RS15755	COG0738	Major facilitator superfamily
SXIN_RS15765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SXIN_RS15780	COG0450	alkyl hydroperoxide reductase
SXIN_RS15790	COG2920	part of a sulfur-relay system
SXIN_RS15825	COG2188	Transcriptional regulator
SXIN_RS15840	COG0596	Alpha beta hydrolase
SXIN_RS15870	COG1470	cell adhesion involved in biofilm formation
SXIN_RS15915	COG2391	methyltransferase activity
SXIN_RS15935	COG2197	response regulator
SXIN_RS15985	COG0717	Belongs to the dCTP deaminase family
SXIN_RS16015	COG2181	nitrate reductase activity
SXIN_RS16015	COG0247	lactate metabolic process
SXIN_RS16020	COG0443	Heat shock 70 kDa protein
SXIN_RS16025	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SXIN_RS16030	COG0484	heat shock protein binding
SXIN_RS16035	COG0789	Transcriptional regulator
SXIN_RS16090	COG3958	Transketolase
SXIN_RS16095	COG3959	Transketolase, thiamine diphosphate binding domain
SXIN_RS16115	COG0542	response to heat
SXIN_RS16145	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SXIN_RS16160	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SXIN_RS16165	COG0191	fructose-bisphosphate aldolase activity
SXIN_RS16175	COG3483	tryptophan 2,3-dioxygenase activity
SXIN_RS16180	COG3844	kynureninase activity
SXIN_RS16190	COG4585	Histidine kinase
SXIN_RS16195	COG2197	response regulator
SXIN_RS16200	COG3559	Exporter of polyketide antibiotics
SXIN_RS16205	COG1131	(ABC) transporter
SXIN_RS16220	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SXIN_RS16255	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SXIN_RS16255	COG0515	serine threonine protein kinase
SXIN_RS16270	COG1802	Transcriptional regulator
SXIN_RS16290	COG0151	Belongs to the GarS family
SXIN_RS16305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SXIN_RS16350	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SXIN_RS16355	COG0047	phosphoribosylformylglycinamidine synthase activity
SXIN_RS16360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SXIN_RS16385	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SXIN_RS16395	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SXIN_RS16415	COG1643	Atp-dependent helicase
SXIN_RS16430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SXIN_RS16430	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SXIN_RS16455	COG2188	Transcriptional regulator
SXIN_RS16495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SXIN_RS16500	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SXIN_RS16510	COG0513	Belongs to the DEAD box helicase family
SXIN_RS16535	COG0741	lytic transglycosylase activity
SXIN_RS16535	COG0739	heme binding
SXIN_RS16535	COG1196	nuclear chromosome segregation
SXIN_RS16550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SXIN_RS16555	COG0579	oxidoreductase
SXIN_RS16560	COG2267	carboxylic ester hydrolase activity
SXIN_RS16585	COG1252	NADH dehydrogenase
SXIN_RS16660	COG1196	nuclear chromosome segregation
SXIN_RS16660	COG0741	lytic transglycosylase activity
SXIN_RS16660	COG0739	heme binding
SXIN_RS16665	COG0671	phosphoesterase, PA-phosphatase related
SXIN_RS16680	COG1937	Protein conserved in bacteria
SXIN_RS16690	COG0306	phosphate transporter
SXIN_RS16780	COG0789	Transcriptional regulator
SXIN_RS16810	COG4552	Acetyltransferase involved in intracellular survival and related
SXIN_RS16825	COG1490	D-aminoacyl-tRNA deacylase activity
SXIN_RS16840	COG0735	belongs to the Fur family
SXIN_RS16850	COG3485	protocatechuate 3,4-dioxygenase
SXIN_RS16885	COG2897	thiosulfate sulfurtransferase activity
SXIN_RS16910	COG0745	RESPONSE REGULATOR receiver
SXIN_RS16915	COG1609	Transcriptional regulator
SXIN_RS16920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SXIN_RS16925	COG0745	RESPONSE REGULATOR receiver
SXIN_RS16935	COG0737	Belongs to the 5'-nucleotidase family
SXIN_RS16940	COG0456	acetyltransferase
SXIN_RS16945	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SXIN_RS16955	COG0406	alpha-ribazole phosphatase activity
SXIN_RS16955	COG0494	nUDIX hydrolase
SXIN_RS16995	COG0438	transferase activity, transferring glycosyl groups
SXIN_RS17005	COG0588	phosphoglycerate mutase activity
SXIN_RS17025	COG5002	protein histidine kinase activity
SXIN_RS17045	COG1329	Transcriptional regulator
SXIN_RS17050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SXIN_RS17055	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SXIN_RS17060	COG3467	pyridoxamine 5'-phosphate
SXIN_RS17065	COG0215	cysteine-tRNA ligase activity
SXIN_RS17080	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SXIN_RS17090	COG3842	ATPase activity
SXIN_RS17100	COG0582	viral genome integration into host DNA
SXIN_RS17145	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
SXIN_RS17150	COG3485	protocatechuate 3,4-dioxygenase
SXIN_RS17175	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SXIN_RS17185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SXIN_RS17205	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SXIN_RS17225	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SXIN_RS17235	COG0463	Glycosyl transferase, family 2
SXIN_RS17250	COG1278	Cold shock
SXIN_RS17260	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SXIN_RS17290	COG3973	AAA domain
SXIN_RS17305	COG1061	Type III restriction enzyme res subunit
SXIN_RS17335	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SXIN_RS17345	COG2814	Major facilitator Superfamily
SXIN_RS17360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SXIN_RS17370	COG2252	PERMEase
SXIN_RS17380	COG2814	Major facilitator Superfamily
SXIN_RS17390	COG0667	Aldo Keto reductase
SXIN_RS17420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SXIN_RS17425	COG0247	lactate metabolic process
SXIN_RS17425	COG0277	FAD linked oxidase domain protein
SXIN_RS17430	COG2197	response regulator
SXIN_RS17440	COG2409	Drug exporters of the RND superfamily
SXIN_RS17465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SXIN_RS17480	COG0318	PFAM AMP-dependent synthetase and ligase
SXIN_RS17500	COG0259	pyridoxamine-phosphate oxidase activity
SXIN_RS17510	COG4821	SIS domain
SXIN_RS17520	COG0596	Alpha beta hydrolase
SXIN_RS17520	COG2945	thiolester hydrolase activity
SXIN_RS17570	COG1366	Belongs to the anti-sigma-factor antagonist family
SXIN_RS17595	COG2072	flavoprotein involved in K transport
SXIN_RS17610	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SXIN_RS17610	COG0515	serine threonine protein kinase
SXIN_RS17625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SXIN_RS17640	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SXIN_RS17665	COG1686	Belongs to the peptidase S11 family
SXIN_RS17680	COG1653	transport
SXIN_RS17695	COG1733	regulation of RNA biosynthetic process
SXIN_RS17820	COG1302	Protein conserved in bacteria
SXIN_RS17860	COG4249	Peptidase C14 caspase catalytic subunit p20
SXIN_RS17860	COG2319	Wd-40 repeat
SXIN_RS17895	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
SXIN_RS17920	COG3547	Transposase (IS116 IS110 IS902 family)
SXIN_RS17955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SXIN_RS17970	COG0501	Belongs to the peptidase M48B family
SXIN_RS18010	COG3384	dioxygenase
SXIN_RS18015	COG1247	-acetyltransferase
SXIN_RS18025	COG1349	DNA-binding transcription factor activity
SXIN_RS18035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SXIN_RS18035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SXIN_RS18035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SXIN_RS18045	COG1970	mechanosensitive ion channel activity
SXIN_RS18055	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SXIN_RS18070	COG3263	regulation of cellular component size
SXIN_RS18080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SXIN_RS18085	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SXIN_RS18095	COG0315	cyclic pyranopterin monophosphate synthase activity
SXIN_RS18100	COG0521	Mo-molybdopterin cofactor biosynthetic process
SXIN_RS18105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SXIN_RS18120	COG1653	transport
SXIN_RS18125	COG4209	transmembrane transport
SXIN_RS18130	COG0395	ABC-type sugar transport system, permease component
SXIN_RS18135	COG1501	Belongs to the glycosyl hydrolase 31 family
SXIN_RS18145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SXIN_RS18175	COG2072	flavoprotein involved in K transport
SXIN_RS18180	COG2267	carboxylic ester hydrolase activity
SXIN_RS18185	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS18195	COG4946	Tricorn protease homolog
SXIN_RS18195	COG0793	Belongs to the peptidase S41A family
SXIN_RS18205	COG2409	Drug exporters of the RND superfamily
SXIN_RS18210	COG0310	cobalt ion transport
SXIN_RS18225	COG1122	ATPase activity
SXIN_RS18230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SXIN_RS18255	COG0084	hydrolase, TatD family'
SXIN_RS18265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SXIN_RS18270	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SXIN_RS18275	COG0488	(ABC) transporter
SXIN_RS18300	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SXIN_RS18305	COG2197	response regulator
SXIN_RS18310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SXIN_RS18315	COG0765	amino acid transport
SXIN_RS18325	COG1024	Enoyl-CoA hydratase
SXIN_RS18340	COG1574	metal-dependent hydrolase with the TIM-barrel fold
SXIN_RS18350	COG1846	Transcriptional regulator
SXIN_RS18355	COG4106	trans-aconitate 2-methyltransferase activity
SXIN_RS18370	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SXIN_RS18380	COG0193	aminoacyl-tRNA hydrolase activity
SXIN_RS18385	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SXIN_RS18390	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SXIN_RS18395	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SXIN_RS18410	COG4585	Histidine kinase
SXIN_RS18440	COG0577	efflux transmembrane transporter activity
SXIN_RS18440	COG1136	(ABC) transporter
SXIN_RS18445	COG0577	efflux transmembrane transporter activity
SXIN_RS18490	COG1216	Glycosyl transferase, family 2
SXIN_RS18520	COG2124	cytochrome p450
SXIN_RS18540	COG0148	phosphopyruvate hydratase activity
SXIN_RS18590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SXIN_RS18595	COG0577	efflux transmembrane transporter activity
SXIN_RS18600	COG1136	(ABC) transporter
SXIN_RS18600	COG0577	efflux transmembrane transporter activity
SXIN_RS18610	COG0667	Aldo Keto reductase
SXIN_RS18620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SXIN_RS18620	COG1199	ATP-dependent helicase activity
SXIN_RS18630	COG0105	UTP biosynthetic process
SXIN_RS18700	COG0183	Belongs to the thiolase family
SXIN_RS18705	COG2755	lipolytic protein G-D-S-L family
SXIN_RS18720	COG0318	PFAM AMP-dependent synthetase and ligase
SXIN_RS18740	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SXIN_RS18745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SXIN_RS18755	COG1228	amidohydrolase
SXIN_RS18760	COG1191	sigma factor activity
SXIN_RS18765	COG1366	Belongs to the anti-sigma-factor antagonist family
SXIN_RS18780	COG1278	Cold shock
SXIN_RS18785	COG0745	RESPONSE REGULATOR receiver
SXIN_RS18790	COG2205	protein histidine kinase activity
SXIN_RS18820	COG0247	lactate metabolic process
SXIN_RS18825	COG0277	FAD linked oxidase domain protein
SXIN_RS18835	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SXIN_RS18845	COG1316	TRANSCRIPTIONal
SXIN_RS18850	COG1607	acyl-coa hydrolase
SXIN_RS18870	COG1316	TRANSCRIPTIONal
SXIN_RS18875	COG1316	TRANSCRIPTIONal
SXIN_RS18900	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
SXIN_RS18900	COG0778	Nitroreductase
SXIN_RS18905	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SXIN_RS18940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SXIN_RS18955	COG1482	cell wall glycoprotein biosynthetic process
SXIN_RS18965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SXIN_RS18965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SXIN_RS18965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SXIN_RS18970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SXIN_RS18970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SXIN_RS18970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SXIN_RS18980	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SXIN_RS19020	COG0714	Associated with various cellular activities
SXIN_RS19040	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SXIN_RS19045	COG0745	RESPONSE REGULATOR receiver
SXIN_RS19050	COG5002	protein histidine kinase activity
SXIN_RS19055	COG0823	Involved in the tonB-independent uptake of proteins
SXIN_RS19065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SXIN_RS19075	COG3214	Protein conserved in bacteria
SXIN_RS19080	COG0653	protein targeting
SXIN_RS19100	COG2902	Dehydrogenase
SXIN_RS19105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SXIN_RS19110	COG0438	transferase activity, transferring glycosyl groups
SXIN_RS19115	COG1215	transferase activity, transferring glycosyl groups
SXIN_RS19135	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SXIN_RS19140	COG0395	ABC-type sugar transport system, permease component
SXIN_RS19145	COG1175	transmembrane transport
SXIN_RS19155	COG1674	ftsk spoiiie
SXIN_RS19160	COG0515	serine threonine protein kinase
SXIN_RS19165	COG0515	serine threonine protein kinase
SXIN_RS19170	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SXIN_RS19185	COG2884	Cell division ATP-binding protein ftsE
SXIN_RS19190	COG2177	Part of the ABC transporter FtsEX involved in
SXIN_RS19195	COG0793	Belongs to the peptidase S41A family
SXIN_RS19200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SXIN_RS19215	COG1414	Transcriptional regulator
SXIN_RS19220	COG0402	S-adenosylhomocysteine deaminase activity
SXIN_RS19225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SXIN_RS19235	COG3384	dioxygenase
SXIN_RS19250	COG0583	DNA-binding transcription factor activity
SXIN_RS19255	COG2223	nitrite transmembrane transporter activity
SXIN_RS19285	COG3973	AAA domain
SXIN_RS19285	COG3973	AAA domain
SXIN_RS19300	COG0776	regulation of translation
SXIN_RS19305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SXIN_RS19310	COG1678	Uncharacterized ACR, COG1678
SXIN_RS19330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SXIN_RS19370	COG3185	4-Hydroxyphenylpyruvate dioxygenase
SXIN_RS19375	COG0277	FAD linked oxidase domain protein
SXIN_RS19410	COG1335	isochorismatase
SXIN_RS19420	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SXIN_RS19450	COG1234	tRNA 3'-trailer cleavage
SXIN_RS19455	COG1263	PTS System
SXIN_RS19460	COG1263	PTS System
SXIN_RS19465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SXIN_RS19470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SXIN_RS19480	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SXIN_RS19510	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SXIN_RS19515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SXIN_RS19545	COG1253	flavin adenine dinucleotide binding
SXIN_RS19585	COG2733	membrane
SXIN_RS19590	COG1357	PFAM Pentapeptide repeats (8 copies)
SXIN_RS19730	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SXIN_RS19760	COG0706	membrane insertase activity
SXIN_RS19765	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS19770	COG1309	transcriptional regulator
SXIN_RS19785	COG4702	Belongs to the UPF0303 family
SXIN_RS19790	COG0673	inositol 2-dehydrogenase activity
SXIN_RS19910	COG0477	Major facilitator Superfamily
SXIN_RS19930	COG0778	Nitroreductase
SXIN_RS19940	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SXIN_RS19945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SXIN_RS19950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SXIN_RS19970	COG0596	Alpha beta hydrolase
SXIN_RS19980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SXIN_RS19985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SXIN_RS20010	COG0318	PFAM AMP-dependent synthetase and ligase
SXIN_RS20020	COG0604	alcohol dehydrogenase
SXIN_RS20020	COG3321	synthase
SXIN_RS20030	COG2197	response regulator
SXIN_RS20050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SXIN_RS20055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SXIN_RS20060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SXIN_RS20110	COG3397	chitin binding
SXIN_RS20140	COG1126	abc transporter atp-binding protein
SXIN_RS20145	COG0765	amino acid transport
SXIN_RS20150	COG0765	amino acid transport
SXIN_RS20155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SXIN_RS20165	COG0154	amidase activity
SXIN_RS20180	COG3473	Maleate cis-trans isomerase
SXIN_RS20195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SXIN_RS20200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SXIN_RS20250	COG1993	acr, cog1993
SXIN_RS20265	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SXIN_RS20285	COG2197	response regulator
SXIN_RS20290	COG0475	glutathione-regulated potassium exporter activity
SXIN_RS20295	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SXIN_RS20300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SXIN_RS20310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SXIN_RS20315	COG0235	Class ii aldolase
SXIN_RS20315	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SXIN_RS20320	COG2197	response regulator
SXIN_RS20395	COG0745	RESPONSE REGULATOR receiver
SXIN_RS20410	COG0395	ABC-type sugar transport system, permease component
SXIN_RS20415	COG1175	transmembrane transport
SXIN_RS20430	COG5297	Belongs to the glycosyl hydrolase family 6
SXIN_RS20440	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SXIN_RS20445	COG4977	sequence-specific DNA binding
SXIN_RS20450	COG0589	response to stress
SXIN_RS20455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SXIN_RS20510	COG0515	serine threonine protein kinase
SXIN_RS20520	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS20535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SXIN_RS20540	COG1309	transcriptional regulator
SXIN_RS20550	COG1946	Acyl-CoA thioesterase
SXIN_RS20590	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
SXIN_RS20630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SXIN_RS20655	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SXIN_RS20660	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SXIN_RS20670	COG1414	Transcriptional regulator
SXIN_RS20675	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SXIN_RS20685	COG0300	oxidoreductase activity
SXIN_RS20710	COG1472	Belongs to the glycosyl hydrolase 3 family
SXIN_RS20735	COG1609	Transcriptional regulator
SXIN_RS20745	COG0673	inositol 2-dehydrogenase activity
SXIN_RS20770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SXIN_RS20775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SXIN_RS20805	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SXIN_RS20810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SXIN_RS20850	COG2409	Drug exporters of the RND superfamily
SXIN_RS20855	COG0673	inositol 2-dehydrogenase activity
SXIN_RS20870	COG3718	enzyme involved in inositol metabolism
SXIN_RS20875	COG3962	Belongs to the TPP enzyme family
SXIN_RS20890	COG1131	(ABC) transporter
SXIN_RS20905	COG2318	DinB family
SXIN_RS20935	COG2255	four-way junction helicase activity
SXIN_RS20940	COG2261	transglycosylase associated protein
SXIN_RS21040	COG0464	growth
SXIN_RS21050	COG2197	response regulator
SXIN_RS21135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SXIN_RS21145	COG0516	GMP reductase activity
SXIN_RS21145	COG0517	IMP dehydrogenase activity
SXIN_RS21150	COG0517	IMP dehydrogenase activity
SXIN_RS21150	COG0516	GMP reductase activity
SXIN_RS21155	COG3547	Transposase (IS116 IS110 IS902 family)
SXIN_RS21175	COG3547	Transposase (IS116 IS110 IS902 family)
SXIN_RS21185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SXIN_RS21185	COG0574	Belongs to the PEP-utilizing enzyme family
SXIN_RS21190	COG1454	alcohol dehydrogenase
SXIN_RS21190	COG1012	belongs to the aldehyde dehydrogenase family
SXIN_RS21205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SXIN_RS21220	COG2223	nitrite transmembrane transporter activity
SXIN_RS21225	COG2207	Transcriptional regulator
SXIN_RS21245	COG0629	single-stranded DNA binding
SXIN_RS21275	COG2197	response regulator
SXIN_RS21280	COG2346	COG2346, Truncated hemoglobins
SXIN_RS21305	COG1486	melibiose metabolic process
SXIN_RS21375	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SXIN_RS21390	COG0698	ribose 5-phosphate isomerase
SXIN_RS21400	COG4552	Acetyltransferase involved in intracellular survival and related
SXIN_RS21480	COG2894	cell division
SXIN_RS21485	COG1674	ftsk spoiiie
SXIN_RS21495	COG3594	Acyltransferase
SXIN_RS21520	COG0544	peptidyl-prolyl cis-trans isomerase activity
SXIN_RS21525	COG0740	serine-type endopeptidase activity
SXIN_RS21530	COG0740	serine-type endopeptidase activity
SXIN_RS21535	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SXIN_RS21550	COG0525	valine-tRNA ligase activity
SXIN_RS21555	COG0285	dihydrofolate synthase activity
SXIN_RS21565	COG0105	UTP biosynthetic process
SXIN_RS21570	COG1077	Cell shape determining protein MreB Mrl
SXIN_RS21585	COG0768	penicillin binding
SXIN_RS21590	COG0772	Belongs to the SEDS family
SXIN_RS21605	COG1530	ribonuclease E activity
SXIN_RS21610	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SXIN_RS21615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SXIN_RS21620	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SXIN_RS21635	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SXIN_RS21645	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SXIN_RS21660	COG0501	Belongs to the peptidase M48B family
SXIN_RS21670	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SXIN_RS21680	COG0799	negative regulation of ribosome biogenesis
SXIN_RS21685	COG0588	phosphoglycerate mutase activity
SXIN_RS21700	COG5650	phosphatidylinositol metabolic process
SXIN_RS21710	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SXIN_RS21720	COG0495	leucyl-tRNA aminoacylation
SXIN_RS21730	COG1307	EDD domain protein, DegV family
SXIN_RS21735	COG1596	polysaccharide export
SXIN_RS21735	COG1555	photosystem II stabilization
SXIN_RS21740	COG2333	competence protein COMEC
SXIN_RS21740	COG0658	competence protein
SXIN_RS21755	COG0268	Binds directly to 16S ribosomal RNA
SXIN_RS21760	COG0481	GTPase activity
SXIN_RS21785	COG1420	regulation of RNA biosynthetic process
SXIN_RS21790	COG0484	heat shock protein binding
SXIN_RS21810	COG4946	Tricorn protease homolog
SXIN_RS21810	COG0793	Belongs to the peptidase S41A family
SXIN_RS21845	COG0537	adenosine 5'-monophosphoramidase activity
SXIN_RS21850	COG1234	tRNA 3'-trailer cleavage
SXIN_RS21860	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SXIN_RS21875	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SXIN_RS21885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SXIN_RS21895	COG1381	Involved in DNA repair and RecF pathway recombination
SXIN_RS21900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SXIN_RS21910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SXIN_RS21915	COG1121	(ABC) transporter
SXIN_RS21920	COG0803	Belongs to the bacterial solute-binding protein 9 family
SXIN_RS21920	COG3443	Belongs to the bacterial solute-binding protein 9 family
SXIN_RS21925	COG0423	glycine-tRNA ligase activity
SXIN_RS21935	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
SXIN_RS21940	COG0574	Belongs to the PEP-utilizing enzyme family
SXIN_RS21940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SXIN_RS21970	COG1175	transmembrane transport
SXIN_RS21975	COG1653	transport
SXIN_RS21980	COG1609	Transcriptional regulator
SXIN_RS21995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SXIN_RS21995	COG2146	nitrite reductase [NAD(P)H] activity
SXIN_RS22000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SXIN_RS22005	COG0300	oxidoreductase activity
SXIN_RS22045	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS22105	COG0243	molybdopterin cofactor binding
SXIN_RS22120	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SXIN_RS22135	COG0358	DNA primase activity
SXIN_RS22145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SXIN_RS22175	COG1070	Carbohydrate kinase
SXIN_RS22195	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
SXIN_RS22225	COG1191	sigma factor activity
SXIN_RS22235	COG0589	response to stress
SXIN_RS22240	COG2267	carboxylic ester hydrolase activity
SXIN_RS22255	COG2508	Transcriptional regulator
SXIN_RS22260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SXIN_RS22275	COG0559	Belongs to the binding-protein-dependent transport system permease family
SXIN_RS22300	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS22315	COG1414	Transcriptional regulator
SXIN_RS22320	COG3386	PFAM SMP-30 Gluconolaconase
SXIN_RS22360	COG4974	Belongs to the 'phage' integrase family
SXIN_RS22370	COG2130	NADP-dependent
SXIN_RS22375	COG1764	response to oxidative stress
SXIN_RS22390	COG1175	transmembrane transport
SXIN_RS22395	COG0395	ABC-type sugar transport system, permease component
SXIN_RS22400	COG3507	Belongs to the glycosyl hydrolase 43 family
SXIN_RS22410	COG3940	Belongs to the glycosyl hydrolase 43 family
SXIN_RS22455	COG4214	carbohydrate transport
SXIN_RS22480	COG4948	Mandelate Racemase Muconate Lactonizing
SXIN_RS22490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SXIN_RS22495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SXIN_RS22500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SXIN_RS22530	COG0789	Transcriptional regulator
SXIN_RS22535	COG0667	Aldo Keto reductase
SXIN_RS22555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SXIN_RS22570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SXIN_RS22575	COG1120	ATPase activity
SXIN_RS22585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SXIN_RS22590	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SXIN_RS22605	COG1309	transcriptional regulator
SXIN_RS22610	COG0477	Major facilitator Superfamily
SXIN_RS22620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SXIN_RS22630	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SXIN_RS22675	COG1358	cellular component organization or biogenesis
SXIN_RS22735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SXIN_RS22765	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SXIN_RS22785	COG0438	transferase activity, transferring glycosyl groups
SXIN_RS22805	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SXIN_RS22945	COG4974	Belongs to the 'phage' integrase family
SXIN_RS22950	COG1793	dna ligase
SXIN_RS22955	COG3285	dna ligase
SXIN_RS22955	COG1793	dna ligase
SXIN_RS22960	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SXIN_RS23075	COG3845	ABC transporter
SXIN_RS23090	COG1657	PFAM Prenyltransferase squalene oxidase
SXIN_RS23095	COG0515	serine threonine protein kinase
SXIN_RS23105	COG1132	(ABC) transporter
SXIN_RS23110	COG1132	(ABC) transporter
SXIN_RS23115	COG2197	response regulator
SXIN_RS23120	COG1309	transcriptional regulator
SXIN_RS23125	COG0438	transferase activity, transferring glycosyl groups
SXIN_RS23160	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS23185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SXIN_RS23200	COG3022	response to hydroperoxide
SXIN_RS23215	COG0789	Transcriptional regulator
SXIN_RS23240	COG0071	Belongs to the small heat shock protein (HSP20) family
SXIN_RS23245	COG3540	Alkaline phosphatase
SXIN_RS23255	COG2814	Major facilitator Superfamily
SXIN_RS23265	COG1309	transcriptional regulator
SXIN_RS23290	COG0297	glycogen (starch) synthase activity
SXIN_RS23295	COG0489	protein tyrosine kinase activity
SXIN_RS23295	COG3206	protein involved in exopolysaccharide biosynthesis
SXIN_RS23310	COG0438	transferase activity, transferring glycosyl groups
SXIN_RS23315	COG0463	Glycosyl transferase, family 2
SXIN_RS23330	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SXIN_RS23335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SXIN_RS23340	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SXIN_RS23345	COG5398	heme oxygenase
SXIN_RS23375	COG1994	Peptidase M50
SXIN_RS23380	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SXIN_RS23380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SXIN_RS23390	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SXIN_RS23395	COG0174	glutamine synthetase
SXIN_RS23410	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SXIN_RS23415	COG0561	phosphatase activity
SXIN_RS23425	COG1609	Transcriptional regulator
SXIN_RS23430	COG0366	Alpha amylase catalytic
SXIN_RS23435	COG2182	Extracellular solute-binding protein
SXIN_RS23440	COG1175	transmembrane transport
SXIN_RS23445	COG3833	ABC-type maltose transport systems, permease component
SXIN_RS23450	COG0366	Alpha amylase catalytic
SXIN_RS23480	COG2318	DinB family
SXIN_RS23530	COG2197	response regulator
SXIN_RS23560	COG0500	methyltransferase
SXIN_RS23575	COG0640	Transcriptional regulator
SXIN_RS23585	COG2318	DinB family
SXIN_RS23590	COG3509	depolymerase
SXIN_RS23650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SXIN_RS23655	COG0321	lipoyl(octanoyl) transferase activity
SXIN_RS23685	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS23695	COG0508	dehydrogenase complex catalyzes the overall conversion of
SXIN_RS23700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SXIN_RS23705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SXIN_RS23710	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SXIN_RS23715	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SXIN_RS23755	COG2197	response regulator
SXIN_RS23760	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SXIN_RS23780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SXIN_RS23790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SXIN_RS23795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SXIN_RS23805	COG1376	ErfK ybiS ycfS ynhG family protein
SXIN_RS23815	COG1845	cytochrome c oxidase, subunit III
SXIN_RS23820	COG2010	Cytochrome c
SXIN_RS23825	COG0723	plastoquinol--plastocyanin reductase activity
SXIN_RS23830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SXIN_RS23835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SXIN_RS23875	COG0438	transferase activity, transferring glycosyl groups
SXIN_RS23895	COG0003	Pfam Anion-transporting ATPase
SXIN_RS23905	COG1940	carbohydrate kinase activity
SXIN_RS23930	COG4585	Histidine kinase
SXIN_RS23935	COG2197	response regulator
SXIN_RS23940	COG0205	6-phosphofructokinase activity
SXIN_RS23945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SXIN_RS23955	COG0456	acetyltransferase
SXIN_RS24000	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SXIN_RS24010	COG2193	ferroxidase activity
SXIN_RS24015	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SXIN_RS24020	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SXIN_RS24040	COG2815	serine threonine protein kinase
SXIN_RS24040	COG0515	serine threonine protein kinase
SXIN_RS24045	COG2022	thiamine diphosphate biosynthetic process
SXIN_RS24055	COG2022	thiamine diphosphate biosynthetic process
SXIN_RS24055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SXIN_RS24070	COG0352	thiamine-phosphate diphosphorylase activity
SXIN_RS24090	COG1309	transcriptional regulator
SXIN_RS24100	COG1121	(ABC) transporter
SXIN_RS24130	COG0714	Associated with various cellular activities
SXIN_RS24140	COG0275	rRNA processing
SXIN_RS24150	COG0768	penicillin binding
SXIN_RS24155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SXIN_RS24160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SXIN_RS24165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SXIN_RS24170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SXIN_RS24180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SXIN_RS24185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SXIN_RS24190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SXIN_RS24195	COG1496	oxidoreductase activity
SXIN_RS24205	COG1799	cell septum assembly
SXIN_RS24215	COG3599	regulation of cell shape
SXIN_RS24220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SXIN_RS24230	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SXIN_RS24270	COG0587	DNA-directed DNA polymerase activity
SXIN_RS24275	COG1432	Conserved Protein
SXIN_RS24295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SXIN_RS24315	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SXIN_RS24320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SXIN_RS24325	COG0131	Imidazoleglycerol-phosphate dehydratase
SXIN_RS24330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SXIN_RS24335	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SXIN_RS24340	COG0251	oxidation-reduction process
SXIN_RS24345	COG0107	imidazoleglycerol-phosphate synthase activity
SXIN_RS24385	COG3548	integral membrane protein
SXIN_RS24395	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SXIN_RS24405	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SXIN_RS24410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SXIN_RS24430	COG0134	indole-3-glycerol-phosphate synthase activity
SXIN_RS24435	COG0133	tryptophan synthase activity
SXIN_RS24440	COG0159	tryptophan synthase activity
SXIN_RS24450	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SXIN_RS24460	COG0069	glutamate synthase activity
SXIN_RS24460	COG0067	glutamate synthase
SXIN_RS24460	COG0070	glutamate synthase
SXIN_RS24480	COG0326	Molecular chaperone. Has ATPase activity
SXIN_RS24510	COG1605	Chorismate mutase
SXIN_RS24510	COG0287	Prephenate dehydrogenase
SXIN_RS24595	COG2050	protein possibly involved in aromatic compounds catabolism
SXIN_RS24620	COG1643	Atp-dependent helicase
SXIN_RS24625	COG2226	methyltransferase
SXIN_RS24640	COG0237	dephospho-CoA kinase activity
SXIN_RS24695	COG2318	DinB family
SXIN_RS24705	COG0477	Major facilitator Superfamily
SXIN_RS24715	COG0584	glycerophosphoryl diester phosphodiesterase
SXIN_RS24720	COG0556	nucleotide-excision repair
SXIN_RS24750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SXIN_RS24755	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SXIN_RS24755	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SXIN_RS24765	COG0322	excinuclease ABC activity
SXIN_RS24770	COG1660	Displays ATPase and GTPase activities
SXIN_RS24775	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SXIN_RS24780	COG1481	regulation of sporulation
SXIN_RS24785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SXIN_RS24790	COG0126	phosphoglycerate kinase activity
SXIN_RS24795	COG0149	triose-phosphate isomerase activity
SXIN_RS24800	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SXIN_RS24815	COG0166	Belongs to the GPI family
SXIN_RS24820	COG0363	glucosamine-6-phosphate deaminase activity
SXIN_RS24835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SXIN_RS24845	COG0109	protoheme IX farnesyltransferase activity
SXIN_RS24855	COG1612	heme a metabolic process
SXIN_RS24870	COG2208	phosphoserine phosphatase activity
SXIN_RS24870	COG2770	Histidine kinase
SXIN_RS24890	COG1131	(ABC) transporter
SXIN_RS24905	COG0719	Fe-S assembly protein
SXIN_RS24915	COG0396	ATPase activity
SXIN_RS24920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SXIN_RS24925	COG0822	iron-sulfur transferase activity
SXIN_RS24935	COG2171	N-acyltransferase activity
SXIN_RS24995	COG0395	ABC-type sugar transport system, permease component
SXIN_RS25000	COG1063	alcohol dehydrogenase
SXIN_RS25005	COG0494	nUDIX hydrolase
SXIN_RS25010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SXIN_RS25020	COG1802	Transcriptional regulator
SXIN_RS25040	COG0395	ABC-type sugar transport system, permease component
SXIN_RS25055	COG3866	Pectate lyase
SXIN_RS25075	COG5285	phytanoyl-CoA dioxygenase
SXIN_RS25080	COG1917	Cupin 2, conserved barrel domain protein
SXIN_RS25085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SXIN_RS25115	COG1797	cobyrinic acid a,c-diamide synthase activity
SXIN_RS25130	COG1492	cobalamin metabolic process
SXIN_RS25135	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SXIN_RS25155	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SXIN_RS25155	COG0235	Class ii aldolase
SXIN_RS25175	COG0488	(ABC) transporter
SXIN_RS25190	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS25195	COG3387	PFAM Glycoside hydrolase 15-related
SXIN_RS25210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SXIN_RS25210	COG1199	ATP-dependent helicase activity
SXIN_RS25220	COG1404	Belongs to the peptidase S8 family
SXIN_RS25235	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SXIN_RS25240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SXIN_RS25255	COG2261	transglycosylase associated protein
SXIN_RS25260	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SXIN_RS25320	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS25325	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SXIN_RS25335	COG2186	Transcriptional regulator
SXIN_RS25360	COG3830	Belongs to the UPF0237 family
SXIN_RS25360	COG0560	Phosphoserine phosphatase
SXIN_RS25370	COG1131	(ABC) transporter
SXIN_RS25370	COG1716	ATPase activity
SXIN_RS25370	COG0842	Transport permease protein
SXIN_RS25380	COG4221	oxidoreductase activity
SXIN_RS25390	COG4585	Histidine kinase
SXIN_RS25395	COG2197	response regulator
SXIN_RS25410	COG1119	ATPase activity
SXIN_RS25435	COG1881	PFAM PEBP family protein
SXIN_RS25445	COG2094	Belongs to the DNA glycosylase MPG family
SXIN_RS25485	COG0647	UMP catabolic process
SXIN_RS25510	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SXIN_RS25515	COG0497	DNA recombination
SXIN_RS25540	COG3387	PFAM Glycoside hydrolase 15-related
SXIN_RS25545	COG0504	CTP synthase activity
SXIN_RS25550	COG0494	nUDIX hydrolase
SXIN_RS25560	COG0686	Belongs to the AlaDH PNT family
SXIN_RS25575	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SXIN_RS25580	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SXIN_RS25585	COG1187	pseudouridine synthase activity
SXIN_RS25595	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SXIN_RS25605	COG1160	GTP binding
SXIN_RS25620	COG0438	transferase activity, transferring glycosyl groups
SXIN_RS25675	COG0671	phosphoesterase, PA-phosphatase related
SXIN_RS25680	COG0477	Major facilitator Superfamily
SXIN_RS25685	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS25690	COG1799	cell septum assembly
SXIN_RS25710	COG0587	DNA-directed DNA polymerase activity
SXIN_RS25720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SXIN_RS25750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SXIN_RS25755	COG1725	Transcriptional regulator
SXIN_RS25775	COG1216	Glycosyl transferase, family 2
SXIN_RS25780	COG0463	Glycosyl transferase, family 2
SXIN_RS25795	COG2755	lipolytic protein G-D-S-L family
SXIN_RS25805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SXIN_RS25815	COG2188	Transcriptional regulator
SXIN_RS25820	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SXIN_RS25825	COG0243	molybdopterin cofactor binding
SXIN_RS25845	COG1937	Protein conserved in bacteria
SXIN_RS25865	COG1960	acyl-CoA dehydrogenase activity
SXIN_RS25895	COG3876	Protein conserved in bacteria
SXIN_RS25900	COG0318	PFAM AMP-dependent synthetase and ligase
SXIN_RS25925	COG2149	membrane
SXIN_RS25995	COG0789	Transcriptional regulator
SXIN_RS26010	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS26015	COG1959	2 iron, 2 sulfur cluster binding
SXIN_RS26020	COG1063	alcohol dehydrogenase
SXIN_RS26100	COG3345	alpha-galactosidase
SXIN_RS26115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SXIN_RS26145	COG0667	Aldo Keto reductase
SXIN_RS26150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SXIN_RS26165	COG0598	Magnesium transport protein CorA
SXIN_RS26185	COG0215	cysteine-tRNA ligase activity
SXIN_RS26195	COG1652	LysM domain
SXIN_RS26195	COG2823	Periplasmic or secreted lipoprotein
SXIN_RS26200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SXIN_RS26205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SXIN_RS26210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SXIN_RS26215	COG1414	Transcriptional regulator
SXIN_RS26220	COG1410	methionine synthase
SXIN_RS26220	COG0646	methionine synthase
SXIN_RS26230	COG4166	transmembrane transport
SXIN_RS26240	COG2197	response regulator
SXIN_RS26250	COG1994	Peptidase M50
SXIN_RS26250	COG0517	IMP dehydrogenase activity
SXIN_RS26275	COG1222	aaa ATPase
SXIN_RS26280	COG4122	O-methyltransferase activity
SXIN_RS26290	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SXIN_RS26295	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SXIN_RS26300	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SXIN_RS26305	COG0545	Peptidyl-prolyl cis-trans isomerase
SXIN_RS26315	COG2378	regulation of single-species biofilm formation
SXIN_RS26335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SXIN_RS26340	COG0805	protein transport
SXIN_RS26355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SXIN_RS26360	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SXIN_RS26365	COG0531	amino acid
SXIN_RS26415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SXIN_RS26425	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SXIN_RS26430	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SXIN_RS26435	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SXIN_RS26440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SXIN_RS26445	COG5002	protein histidine kinase activity
SXIN_RS26450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SXIN_RS26455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SXIN_RS26455	COG0072	phenylalanine-tRNA ligase activity
SXIN_RS26485	COG1649	PFAM Uncharacterised BCR, COG1649
SXIN_RS26510	COG0681	Belongs to the peptidase S26 family
SXIN_RS26515	COG4941	Belongs to the sigma-70 factor family
SXIN_RS26535	COG1595	DNA-templated transcription, initiation
SXIN_RS26545	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SXIN_RS26550	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SXIN_RS26555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SXIN_RS26560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SXIN_RS26565	COG1438	arginine binding
SXIN_RS26585	COG1477	protein flavinylation
SXIN_RS26605	COG0137	argininosuccinate synthase activity
SXIN_RS26610	COG0165	Argininosuccinate lyase
SXIN_RS26630	COG0584	glycerophosphoryl diester phosphodiesterase
SXIN_RS26655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SXIN_RS26660	COG2011	ABC-type metal ion transport system permease component
SXIN_RS26665	COG1464	Belongs to the NlpA lipoprotein family
SXIN_RS26680	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SXIN_RS26685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SXIN_RS26685	COG1648	precorrin-2 dehydrogenase activity
SXIN_RS26745	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SXIN_RS26755	COG0456	acetyltransferase
SXIN_RS26800	COG1175	transmembrane transport
SXIN_RS26805	COG0395	ABC-type sugar transport system, permease component
SXIN_RS26840	COG0300	oxidoreductase activity
SXIN_RS26885	COG3547	Transposase (IS116 IS110 IS902 family)
SXIN_RS26890	COG4715	Zinc finger, swim domain protein
SXIN_RS26895	COG3552	Protein containing von Willebrand factor type A (VWA) domain
SXIN_RS26900	COG2425	protein containing a von Willebrand factor type A (vWA) domain
SXIN_RS26905	COG0714	Associated with various cellular activities
SXIN_RS26910	COG3831	ATPase activity
SXIN_RS26960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SXIN_RS26970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SXIN_RS26980	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS26985	COG1309	transcriptional regulator
SXIN_RS27010	COG0254	rRNA binding
SXIN_RS27015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SXIN_RS27020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SXIN_RS27025	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SXIN_RS27040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SXIN_RS27045	COG1560	Kdo2-lipid A biosynthetic process
SXIN_RS27050	COG0438	transferase activity, transferring glycosyl groups
SXIN_RS27060	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SXIN_RS27065	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SXIN_RS27070	COG0217	transcriptional regulatory protein
SXIN_RS27075	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SXIN_RS27080	COG0632	four-way junction helicase activity
SXIN_RS27085	COG2255	four-way junction helicase activity
SXIN_RS27095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SXIN_RS27100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SXIN_RS27105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SXIN_RS27110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SXIN_RS27115	COG1196	nuclear chromosome segregation
SXIN_RS27120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SXIN_RS27130	COG0124	histidyl-tRNA synthetase
SXIN_RS27155	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SXIN_RS27170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SXIN_RS27175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SXIN_RS27190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SXIN_RS27195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SXIN_RS27200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SXIN_RS27205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SXIN_RS27210	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SXIN_RS27220	COG0006	proline dipeptidase activity
SXIN_RS27225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SXIN_RS27230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SXIN_RS27240	COG0076	glutamate decarboxylase activity
SXIN_RS27250	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SXIN_RS27255	COG0540	Belongs to the ATCase OTCase family
SXIN_RS27260	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SXIN_RS27270	COG0505	Belongs to the CarA family
SXIN_RS27275	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SXIN_RS27280	COG0167	dihydroorotate dehydrogenase activity
SXIN_RS27285	COG0284	orotidine-5'-phosphate decarboxylase activity
SXIN_RS27295	COG0194	GDP metabolic process
SXIN_RS27300	COG1758	RNA polymerase activity
SXIN_RS27310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SXIN_RS27325	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SXIN_RS27345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SXIN_RS27350	COG2390	Transcriptional regulator
SXIN_RS27365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SXIN_RS27380	COG2233	PERMEase
SXIN_RS27400	COG3201	nicotinamide mononucleotide transporter
SXIN_RS27405	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SXIN_RS27405	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SXIN_RS27410	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SXIN_RS27415	COG0140	phosphoribosyl-ATP diphosphatase activity
SXIN_RS27420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SXIN_RS27470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SXIN_RS27485	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SXIN_RS27490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SXIN_RS27520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SXIN_RS27535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SXIN_RS27555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SXIN_RS27560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SXIN_RS27580	COG2318	DinB family
SXIN_RS27585	COG2813	Specifically methylates the guanine in position
SXIN_RS27600	COG1253	flavin adenine dinucleotide binding
SXIN_RS27610	COG0446	pyridine nucleotide-disulphide oxidoreductase
SXIN_RS27610	COG1902	pentaerythritol trinitrate reductase activity
SXIN_RS27645	COG2197	response regulator
SXIN_RS27650	COG4585	Histidine kinase
SXIN_RS27655	COG2409	Drug exporters of the RND superfamily
SXIN_RS27660	COG0596	Alpha beta hydrolase
SXIN_RS27680	COG1012	belongs to the aldehyde dehydrogenase family
SXIN_RS27695	COG3842	ATPase activity
SXIN_RS27725	COG2801	Transposase and inactivated derivatives
SXIN_RS27770	COG2207	Transcriptional regulator
SXIN_RS27775	COG2080	2 iron, 2 sulfur cluster binding
SXIN_RS27780	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SXIN_RS27785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SXIN_RS27815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SXIN_RS27820	COG0657	acetylesterase activity
SXIN_RS27830	COG0583	DNA-binding transcription factor activity
SXIN_RS27840	COG0667	Aldo Keto reductase
SXIN_RS27850	COG0483	inositol monophosphate 1-phosphatase activity
SXIN_RS27885	COG0516	GMP reductase activity
SXIN_RS27885	COG0517	IMP dehydrogenase activity
SXIN_RS27890	COG1042	CoA-binding domain protein
SXIN_RS27890	COG0045	succinate-CoA ligase (ADP-forming) activity
SXIN_RS27890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SXIN_RS27945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SXIN_RS27950	COG0517	IMP dehydrogenase activity
SXIN_RS27950	COG0617	tRNA 3'-terminal CCA addition
SXIN_RS27950	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SXIN_RS27960	COG0569	domain protein
SXIN_RS27965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SXIN_RS27985	COG2409	Drug exporters of the RND superfamily
SXIN_RS28020	COG2706	6-phosphogluconolactonase activity
SXIN_RS28035	COG2375	cellular response to nickel ion
SXIN_RS28060	COG0778	Nitroreductase
SXIN_RS28095	COG0183	Belongs to the thiolase family
SXIN_RS28100	COG0583	DNA-binding transcription factor activity
SXIN_RS28110	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
SXIN_RS28115	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
SXIN_RS28130	COG3509	depolymerase
SXIN_RS28165	COG1472	Belongs to the glycosyl hydrolase 3 family
SXIN_RS28175	COG2814	Major facilitator Superfamily
SXIN_RS28180	COG0492	ferredoxin-NADP+ reductase activity
SXIN_RS28210	COG0395	ABC-type sugar transport system, permease component
SXIN_RS28250	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS28260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SXIN_RS28275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SXIN_RS28305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SXIN_RS28310	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SXIN_RS28315	COG2080	2 iron, 2 sulfur cluster binding
SXIN_RS28345	COG2124	cytochrome p450
SXIN_RS28385	COG1115	amino acid carrier protein
SXIN_RS28390	COG0753	catalase activity
SXIN_RS28410	COG1686	Belongs to the peptidase S11 family
SXIN_RS28425	COG1366	Belongs to the anti-sigma-factor antagonist family
SXIN_RS28425	COG2208	phosphoserine phosphatase activity
SXIN_RS28425	COG2172	sigma factor antagonist activity
SXIN_RS28430	COG1461	Dihydroxyacetone kinase
SXIN_RS28450	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SXIN_RS28460	COG1216	Glycosyl transferase, family 2
SXIN_RS28480	COG3030	protein affecting phage T7 exclusion by the F plasmid
SXIN_RS28490	COG2270	Major facilitator Superfamily
SXIN_RS28530	COG3458	cephalosporin-C deacetylase activity
SXIN_RS28550	COG0739	heme binding
SXIN_RS28565	COG1316	TRANSCRIPTIONal
SXIN_RS28575	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SXIN_RS28580	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SXIN_RS28585	COG1077	Cell shape determining protein MreB Mrl
SXIN_RS28605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SXIN_RS28610	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SXIN_RS28615	COG2080	2 iron, 2 sulfur cluster binding
SXIN_RS28620	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SXIN_RS28620	COG1796	DNA polymerase
SXIN_RS28625	COG1335	isochorismatase
SXIN_RS28630	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS28645	COG1793	dna ligase
SXIN_RS28650	COG1295	ribonuclease BN
SXIN_RS28660	COG0300	oxidoreductase activity
SXIN_RS28685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SXIN_RS28690	COG2192	nodulation
SXIN_RS28720	COG3290	protein histidine kinase activity
SXIN_RS28725	COG4565	transcriptional regulatory protein
SXIN_RS28750	COG1196	nuclear chromosome segregation
SXIN_RS28750	COG0739	heme binding
SXIN_RS28750	COG0741	lytic transglycosylase activity
SXIN_RS28770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SXIN_RS28785	COG3708	Transcriptional regulator
SXIN_RS28785	COG2207	Transcriptional regulator
SXIN_RS28790	COG1012	belongs to the aldehyde dehydrogenase family
SXIN_RS28800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SXIN_RS28855	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SXIN_RS28870	COG0297	glycogen (starch) synthase activity
SXIN_RS28875	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SXIN_RS28880	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SXIN_RS28880	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SXIN_RS28885	COG0859	PFAM glycosyl transferase family 9
SXIN_RS28960	COG1024	Enoyl-CoA hydratase
SXIN_RS28960	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SXIN_RS28965	COG1032	radical SAM domain protein
SXIN_RS28975	COG0028	Belongs to the TPP enzyme family
SXIN_RS28980	COG3387	PFAM Glycoside hydrolase 15-related
SXIN_RS28990	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS28995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SXIN_RS29005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SXIN_RS29055	COG0243	molybdopterin cofactor binding
SXIN_RS29085	COG3594	Acyltransferase
SXIN_RS29110	COG1028	Short-chain dehydrogenase reductase Sdr
SXIN_RS29145	COG2249	NAD(P)H dehydrogenase (quinone) activity
SXIN_RS29150	COG0784	Response regulator, receiver
SXIN_RS29155	COG4251	negative regulation of phosphorylation
SXIN_RS29165	COG2356	endonuclease I
SXIN_RS29175	COG0583	DNA-binding transcription factor activity
SXIN_RS29200	COG1320	monovalent cation:proton antiporter activity
SXIN_RS29215	COG0651	ATP synthesis coupled electron transport
SXIN_RS29220	COG1006	Multisubunit Na H antiporter MnhC subunit
SXIN_RS29225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SXIN_RS29225	COG2111	Na H antiporter
SXIN_RS29245	COG1609	Transcriptional regulator
SXIN_RS29250	COG3940	Belongs to the glycosyl hydrolase 43 family
SXIN_RS29280	COG1742	UPF0060 membrane protein
SXIN_RS29315	COG0726	polysaccharide deacetylase
SXIN_RS29320	COG4552	Acetyltransferase involved in intracellular survival and related
SXIN_RS29355	COG0589	response to stress
SXIN_RS29365	COG1937	Protein conserved in bacteria
SXIN_RS29370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SXIN_RS29370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SXIN_RS29375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SXIN_RS29380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SXIN_RS29390	COG0395	ABC-type sugar transport system, permease component
SXIN_RS29395	COG1175	transmembrane transport
SXIN_RS29425	COG1030	water channel activity
SXIN_RS29430	COG0330	HflC and HflK could
SXIN_RS29485	COG2890	protein-(glutamine-N5) methyltransferase activity
SXIN_RS29505	COG2326	polyphosphate kinase activity
SXIN_RS29530	COG3424	synthase
SXIN_RS29535	COG2124	cytochrome p450
SXIN_RS29545	COG1940	carbohydrate kinase activity
SXIN_RS29550	COG4214	carbohydrate transport
SXIN_RS29560	COG4213	ABC transporter substrate-binding protein
SXIN_RS29575	COG2409	Drug exporters of the RND superfamily
SXIN_RS29595	COG3629	intracellular signal transduction
SXIN_RS29595	COG3903	Transcriptional regulator
SXIN_RS29615	COG4585	Histidine kinase
SXIN_RS29620	COG2197	response regulator
SXIN_RS29635	COG0612	Peptidase, M16
SXIN_RS29645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SXIN_RS29675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SXIN_RS29685	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SXIN_RS29685	COG1918	ferrous iron import across plasma membrane
SXIN_RS29695	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
SXIN_RS29725	COG2197	response regulator
SXIN_RS29730	COG4585	Histidine kinase
SXIN_RS29755	COG0009	L-threonylcarbamoyladenylate synthase
SXIN_RS29785	COG3655	Transcriptional regulator
SXIN_RS29815	COG1132	(ABC) transporter
SXIN_RS29870	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SXIN_RS30110	COG1192	Involved in chromosome partitioning
SXIN_RS30335	COG1857	crispr-associated protein
SXIN_RS30350	COG1518	maintenance of DNA repeat elements
SXIN_RS30355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SXIN_RS30420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SXIN_RS30475	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SXIN_RS30540	COG1652	LysM domain
SXIN_RS30540	COG2823	Periplasmic or secreted lipoprotein
SXIN_RS30710	COG0482	sulfurtransferase activity
SXIN_RS30715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family