locus-tag	class	description
LLJ08_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LLJ08_RS00010	COG0592	DNA-directed DNA polymerase activity
LLJ08_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LLJ08_RS00030	COG3706	GGDEF domain
LLJ08_RS00045	COG0751	glycine-tRNA ligase activity
LLJ08_RS00055	COG2818	Glycosylase
LLJ08_RS00075	COG1126	abc transporter atp-binding protein
LLJ08_RS00080	COG0765	amino acid transport
LLJ08_RS00085	COG0765	amino acid transport
LLJ08_RS00090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLJ08_RS00095	COG0569	domain protein
LLJ08_RS00100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LLJ08_RS00105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LLJ08_RS00110	COG0242	peptide deformylase activity
LLJ08_RS00115	COG1652	LysM domain
LLJ08_RS00120	COG0758	DNA mediated transformation
LLJ08_RS00125	COG0009	L-threonylcarbamoyladenylate synthase
LLJ08_RS00135	COG0408	coproporphyrinogen oxidase activity
LLJ08_RS00140	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LLJ08_RS00155	COG1686	Belongs to the peptidase S11 family
LLJ08_RS00210	COG0583	DNA-binding transcription factor activity
LLJ08_RS00215	COG2323	membrane
LLJ08_RS00245	COG1132	(ABC) transporter
LLJ08_RS00250	COG3340	Belongs to the peptidase S51 family
LLJ08_RS00280	COG0625	glutathione transferase activity
LLJ08_RS00285	COG1396	sequence-specific DNA binding
LLJ08_RS00290	COG3550	peptidyl-serine autophosphorylation
LLJ08_RS00310	COG0159	tryptophan synthase activity
LLJ08_RS00330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LLJ08_RS00350	COG1132	(ABC) transporter
LLJ08_RS00355	COG4249	Peptidase C14 caspase catalytic subunit p20
LLJ08_RS00360	COG3360	Dodecin
LLJ08_RS00370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LLJ08_RS00410	COG2358	TRAP transporter, solute receptor (TAXI family
LLJ08_RS00425	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LLJ08_RS00435	COG3454	Phosphonate metabolism
LLJ08_RS00440	COG4778	phosphonate C-P lyase system protein PhnL
LLJ08_RS00445	COG4107	phosphonate C-P lyase system protein PhnK
LLJ08_RS00450	COG3627	carbon phosphorus lyase activity
LLJ08_RS00455	COG3626	phosphonate metabolism
LLJ08_RS00465	COG3624	Phosphonate C-P lyase system protein PhnG
LLJ08_RS00470	COG2188	Transcriptional regulator
LLJ08_RS00475	COG3639	organic phosphonate transmembrane transporter activity
LLJ08_RS00480	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LLJ08_RS00490	COG4221	oxidoreductase activity
LLJ08_RS00500	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LLJ08_RS00505	COG3052	prosthetic group binding
LLJ08_RS00525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LLJ08_RS00540	COG0840	transmembrane signaling receptor activity
LLJ08_RS00555	COG4944	Protein of unknown function (DUF1109)
LLJ08_RS00560	COG1595	DNA-templated transcription, initiation
LLJ08_RS00570	COG3220	belongs to the UPF0276 family
LLJ08_RS00590	COG3675	Pfam Lipase (class 3)
LLJ08_RS00610	COG2204	response regulator
LLJ08_RS00670	COG0676	glucose-6-phosphate 1-epimerase activity
LLJ08_RS00685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLJ08_RS00695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LLJ08_RS00740	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LLJ08_RS00745	COG1194	a g-specific adenine glycosylase
LLJ08_RS00760	COG1116	anion transmembrane transporter activity
LLJ08_RS00770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LLJ08_RS00775	COG3707	response regulator
LLJ08_RS00780	COG0131	Imidazoleglycerol-phosphate dehydratase
LLJ08_RS00795	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LLJ08_RS00800	COG0107	imidazoleglycerol-phosphate synthase activity
LLJ08_RS00820	COG0793	Belongs to the peptidase S41A family
LLJ08_RS00825	COG4942	peptidase
LLJ08_RS00830	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LLJ08_RS00835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLJ08_RS00845	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LLJ08_RS00870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LLJ08_RS00890	COG3079	Belongs to the UPF0149 family
LLJ08_RS00895	COG0006	proline dipeptidase activity
LLJ08_RS00900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LLJ08_RS00910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LLJ08_RS00920	COG1178	ABC-type Fe3 transport system permease component
LLJ08_RS00935	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LLJ08_RS00935	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LLJ08_RS00940	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LLJ08_RS00965	COG3023	N-Acetylmuramoyl-L-alanine amidase
LLJ08_RS00975	COG5002	protein histidine kinase activity
LLJ08_RS00980	COG2204	response regulator
LLJ08_RS01000	COG0700	Nucleoside recognition
LLJ08_RS01010	COG2358	TRAP transporter, solute receptor (TAXI family
LLJ08_RS01015	COG0840	transmembrane signaling receptor activity
LLJ08_RS01025	COG0840	transmembrane signaling receptor activity
LLJ08_RS01030	COG5001	Diguanylate cyclase
LLJ08_RS01030	COG4251	negative regulation of phosphorylation
LLJ08_RS01030	COG3706	GGDEF domain
LLJ08_RS01030	COG2203	Gaf domain
LLJ08_RS01070	COG3180	Ammonia monooxygenase
LLJ08_RS01075	COG1283	sodium-dependent phosphate transmembrane transporter activity
LLJ08_RS01085	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LLJ08_RS01090	COG1074	ATP-dependent DNA helicase activity
LLJ08_RS01095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LLJ08_RS01110	COG5002	protein histidine kinase activity
LLJ08_RS01110	COG5001	Diguanylate cyclase
LLJ08_RS01110	COG3447	MASE1 domain protein
LLJ08_RS01115	COG1607	acyl-coa hydrolase
LLJ08_RS01130	COG0573	inorganic phosphate transmembrane transporter activity
LLJ08_RS01135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LLJ08_RS01140	COG0704	Plays a role in the regulation of phosphate uptake
LLJ08_RS01155	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LLJ08_RS01165	COG0584	glycerophosphoryl diester phosphodiesterase
LLJ08_RS01215	COG2205	protein histidine kinase activity
LLJ08_RS01220	COG0745	RESPONSE REGULATOR receiver
LLJ08_RS01225	COG0129	dihydroxy-acid dehydratase activity
LLJ08_RS01235	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LLJ08_RS01240	COG0693	protein deglycase activity
LLJ08_RS01250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LLJ08_RS01270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LLJ08_RS01280	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LLJ08_RS01315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LLJ08_RS01330	COG0742	ribosomal rna small subunit methyltransferase
LLJ08_RS01335	COG0612	Peptidase, M16
LLJ08_RS01340	COG0612	Peptidase, M16
LLJ08_RS01345	COG0552	protein localization to endoplasmic reticulum
LLJ08_RS01350	COG2884	Cell division ATP-binding protein ftsE
LLJ08_RS01355	COG2177	Part of the ABC transporter FtsEX involved in
LLJ08_RS01375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLJ08_RS01380	COG2363	Small membrane protein
LLJ08_RS01390	COG2022	thiamine diphosphate biosynthetic process
LLJ08_RS01395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LLJ08_RS01415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LLJ08_RS01420	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LLJ08_RS01430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LLJ08_RS01430	COG2813	Specifically methylates the guanine in position
LLJ08_RS01435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LLJ08_RS01485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LLJ08_RS01490	COG0540	Belongs to the ATCase OTCase family
LLJ08_RS01500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LLJ08_RS01505	COG1678	Uncharacterized ACR, COG1678
LLJ08_RS01545	COG0784	Response regulator, receiver
LLJ08_RS01545	COG2198	Histidine kinase
LLJ08_RS01545	COG0643	Histidine kinase
LLJ08_RS01550	COG2201	protein-glutamate methylesterase activity
LLJ08_RS01560	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LLJ08_RS01570	COG3038	cytochrome b561
LLJ08_RS01575	COG2353	YceI-like domain
LLJ08_RS01580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LLJ08_RS01595	COG0513	Belongs to the DEAD box helicase family
LLJ08_RS01600	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LLJ08_RS01605	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LLJ08_RS01625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LLJ08_RS01630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LLJ08_RS01635	COG1131	(ABC) transporter
LLJ08_RS01640	COG0842	Transport permease protein
LLJ08_RS01650	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LLJ08_RS01655	COG2226	methyltransferase
LLJ08_RS01665	COG2175	clavaminate synthase activity
LLJ08_RS01670	COG0583	DNA-binding transcription factor activity
LLJ08_RS01675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LLJ08_RS01680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LLJ08_RS01685	COG0126	phosphoglycerate kinase activity
LLJ08_RS01700	COG0191	fructose-bisphosphate aldolase activity
LLJ08_RS01740	COG2081	HI0933 family
LLJ08_RS01750	COG1289	transmembrane transporter activity
LLJ08_RS01755	COG0513	Belongs to the DEAD box helicase family
LLJ08_RS01770	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LLJ08_RS01850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LLJ08_RS01860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LLJ08_RS01885	COG0583	DNA-binding transcription factor activity
LLJ08_RS01910	COG4948	Mandelate Racemase Muconate Lactonizing
LLJ08_RS01915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LLJ08_RS01920	COG1012	belongs to the aldehyde dehydrogenase family
LLJ08_RS01930	COG2721	sulfolactate sulfo-lyase activity
LLJ08_RS01935	COG4774	siderophore transport
LLJ08_RS01955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LLJ08_RS01975	COG0330	HflC and HflK could
LLJ08_RS02000	COG2205	protein histidine kinase activity
LLJ08_RS02000	COG3437	response regulator, receiver
LLJ08_RS02000	COG3850	Histidine kinase
LLJ08_RS02000	COG4999	Histidine kinase
LLJ08_RS02005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LLJ08_RS02020	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LLJ08_RS02025	COG3264	Mechanosensitive ion channel
LLJ08_RS02025	COG1196	nuclear chromosome segregation
LLJ08_RS02030	COG3263	regulation of cellular component size
LLJ08_RS02035	COG1960	acyl-CoA dehydrogenase activity
LLJ08_RS02045	COG1304	FMN binding
LLJ08_RS02080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LLJ08_RS02085	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LLJ08_RS02090	COG1040	competence protein
LLJ08_RS02095	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LLJ08_RS02100	COG0156	8-amino-7-oxononanoate synthase activity
LLJ08_RS02105	COG1073	alpha beta
LLJ08_RS02105	COG2226	methyltransferase
LLJ08_RS02125	COG1960	acyl-CoA dehydrogenase activity
LLJ08_RS02135	COG1960	acyl-CoA dehydrogenase activity
LLJ08_RS02140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLJ08_RS02165	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LLJ08_RS02175	COG0859	PFAM glycosyl transferase family 9
LLJ08_RS02180	COG0859	PFAM glycosyl transferase family 9
LLJ08_RS02185	COG0438	transferase activity, transferring glycosyl groups
LLJ08_RS02210	COG2192	nodulation
LLJ08_RS02215	COG1216	Glycosyl transferase, family 2
LLJ08_RS02245	COG1132	(ABC) transporter
LLJ08_RS02260	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LLJ08_RS02260	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LLJ08_RS02270	COG0667	Aldo Keto reductase
LLJ08_RS02285	COG1519	Transferase
LLJ08_RS02290	COG1538	Outer membrane efflux protein
LLJ08_RS02295	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LLJ08_RS02305	COG0494	nUDIX hydrolase
LLJ08_RS02315	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LLJ08_RS02320	COG3150	esterase
LLJ08_RS02360	COG0560	Phosphoserine phosphatase
LLJ08_RS02360	COG3830	Belongs to the UPF0237 family
LLJ08_RS02365	COG1063	alcohol dehydrogenase
LLJ08_RS02370	COG2200	EAL domain
LLJ08_RS02380	COG0688	phosphatidylethanolamine metabolic process
LLJ08_RS02395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LLJ08_RS02400	COG1360	Flagellar Motor Protein
LLJ08_RS02405	COG1162	GTPase activity
LLJ08_RS02415	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LLJ08_RS02420	COG0702	epimerase
LLJ08_RS02440	COG1346	cytolysis
LLJ08_RS02450	COG2267	carboxylic ester hydrolase activity
LLJ08_RS02455	COG0586	Pfam SNARE associated Golgi protein
LLJ08_RS02460	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LLJ08_RS02465	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LLJ08_RS02475	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LLJ08_RS02480	COG0768	penicillin binding
LLJ08_RS02485	COG0772	Belongs to the SEDS family
LLJ08_RS02490	COG2951	lytic endotransglycosylase activity
LLJ08_RS02500	COG1686	Belongs to the peptidase S11 family
LLJ08_RS02505	COG2921	Belongs to the UPF0250 family
LLJ08_RS02510	COG0321	lipoyl(octanoyl) transferase activity
LLJ08_RS02515	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LLJ08_RS02525	COG2951	lytic endotransglycosylase activity
LLJ08_RS02545	COG0495	leucyl-tRNA aminoacylation
LLJ08_RS02560	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LLJ08_RS02565	COG4535	Mg2 and Co2 transporter CorC
LLJ08_RS02570	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LLJ08_RS02575	COG1702	phosphate starvation-inducible protein PhoH
LLJ08_RS02580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LLJ08_RS02595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LLJ08_RS02600	COG0352	thiamine-phosphate diphosphorylase activity
LLJ08_RS02605	COG0351	phosphomethylpyrimidine kinase
LLJ08_RS02605	COG0352	thiamine-phosphate diphosphorylase activity
LLJ08_RS02610	COG3437	response regulator, receiver
LLJ08_RS02610	COG3850	Histidine kinase
LLJ08_RS02610	COG2205	protein histidine kinase activity
LLJ08_RS02610	COG4999	Histidine kinase
LLJ08_RS02615	COG1960	acyl-CoA dehydrogenase activity
LLJ08_RS02625	COG0427	acetyl-CoA hydrolase
LLJ08_RS02630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LLJ08_RS02645	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LLJ08_RS02650	COG0830	nickel cation binding
LLJ08_RS02655	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LLJ08_RS02670	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LLJ08_RS02680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LLJ08_RS02690	COG1953	Uracil, thiamine, allantoin
LLJ08_RS02700	COG0804	urea catabolic process
LLJ08_RS02705	COG0832	Belongs to the urease beta subunit family
LLJ08_RS02715	COG0831	urea catabolic process
LLJ08_RS02720	COG0829	nickel cation binding
LLJ08_RS02765	COG1522	sequence-specific DNA binding
LLJ08_RS02785	COG1643	Atp-dependent helicase
LLJ08_RS02795	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS02815	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LLJ08_RS02820	COG0142	geranyltranstransferase activity
LLJ08_RS02825	COG1722	exodeoxyribonuclease VII activity
LLJ08_RS02850	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LLJ08_RS02855	COG0076	glutamate decarboxylase activity
LLJ08_RS02865	COG5001	Diguanylate cyclase
LLJ08_RS02875	COG3706	GGDEF domain
LLJ08_RS02885	COG3228	Belongs to the MtfA family
LLJ08_RS02900	COG4303	Ethanolamine ammonia lyase large subunit
LLJ08_RS02915	COG1454	alcohol dehydrogenase
LLJ08_RS02920	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LLJ08_RS02945	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LLJ08_RS02945	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LLJ08_RS02950	COG0802	atpase or kinase
LLJ08_RS02955	COG0860	N-Acetylmuramoyl-L-alanine amidase
LLJ08_RS02960	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LLJ08_RS02965	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LLJ08_RS02970	COG1923	regulation of RNA biosynthetic process
LLJ08_RS02975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LLJ08_RS02980	COG0330	HflC and HflK could
LLJ08_RS02985	COG0330	HflC and HflK could
LLJ08_RS02990	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LLJ08_RS02995	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LLJ08_RS03010	COG0557	exoribonuclease II activity
LLJ08_RS03015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LLJ08_RS03025	COG0360	Binds together with S18 to 16S ribosomal RNA
LLJ08_RS03030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LLJ08_RS03040	COG0359	binds to the 23S rRNA
LLJ08_RS03045	COG0305	Participates in initiation and elongation during chromosome replication
LLJ08_RS03050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LLJ08_RS03135	COG1252	NADH dehydrogenase
LLJ08_RS03160	COG2945	thiolester hydrolase activity
LLJ08_RS03170	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LLJ08_RS03180	COG1515	deoxyribonuclease V activity
LLJ08_RS03185	COG3023	N-Acetylmuramoyl-L-alanine amidase
LLJ08_RS03200	COG0084	hydrolase, TatD family'
LLJ08_RS03210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LLJ08_RS03210	COG2169	Transcriptional regulator
LLJ08_RS03220	COG1538	Outer membrane efflux protein
LLJ08_RS03225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LLJ08_RS03240	COG0840	transmembrane signaling receptor activity
LLJ08_RS03250	COG2217	Heavy metal translocating P-type atpase
LLJ08_RS03265	COG2814	Major facilitator Superfamily
LLJ08_RS03275	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LLJ08_RS03305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LLJ08_RS03310	COG0778	Nitroreductase
LLJ08_RS03315	COG0596	Alpha beta hydrolase
LLJ08_RS03320	COG0251	oxidation-reduction process
LLJ08_RS03325	COG1335	isochorismatase
LLJ08_RS03330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LLJ08_RS03335	COG1309	transcriptional regulator
LLJ08_RS03365	COG4977	sequence-specific DNA binding
LLJ08_RS03370	COG1902	pentaerythritol trinitrate reductase activity
LLJ08_RS03375	COG0640	Transcriptional regulator
LLJ08_RS03385	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LLJ08_RS03395	COG1253	flavin adenine dinucleotide binding
LLJ08_RS03405	COG0346	lactoylglutathione lyase activity
LLJ08_RS03440	COG3845	ABC transporter
LLJ08_RS03450	COG1079	Belongs to the binding-protein-dependent transport system permease family
LLJ08_RS03470	COG1278	Cold shock
LLJ08_RS03475	COG2824	Alkylphosphonate utilization operon protein PhnA
LLJ08_RS03480	COG1607	acyl-coa hydrolase
LLJ08_RS03490	COG0402	S-adenosylhomocysteine deaminase activity
LLJ08_RS03495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LLJ08_RS03500	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
LLJ08_RS03515	COG2154	pterin-4-alpha-carbinolamine dehydratase
LLJ08_RS03530	COG1760	l-serine dehydratase
LLJ08_RS03535	COG0492	ferredoxin-NADP+ reductase activity
LLJ08_RS03565	COG1960	acyl-CoA dehydrogenase activity
LLJ08_RS03570	COG0348	domain, Protein
LLJ08_RS03570	COG3901	Regulator of nitric oxide reductase transcription
LLJ08_RS03575	COG4263	nitrous-oxide reductase activity
LLJ08_RS03590	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LLJ08_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS03620	COG3278	Belongs to the heme-copper respiratory oxidase family
LLJ08_RS03640	COG1648	precorrin-2 dehydrogenase activity
LLJ08_RS03640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LLJ08_RS03645	COG0535	radical SAM domain protein
LLJ08_RS03655	COG1845	cytochrome c oxidase, subunit III
LLJ08_RS03660	COG0714	Associated with various cellular activities
LLJ08_RS03665	COG2010	Cytochrome c
LLJ08_RS03685	COG2010	Cytochrome c
LLJ08_RS03690	COG3391	amine dehydrogenase activity
LLJ08_RS03715	COG2010	Cytochrome c
LLJ08_RS03720	COG3256	nitric oxide reductase
LLJ08_RS03735	COG4580	involved in the transport of maltose and maltodextrins
LLJ08_RS03750	COG0366	Alpha amylase catalytic
LLJ08_RS03760	COG1175	transmembrane transport
LLJ08_RS03765	COG3833	ABC-type maltose transport systems, permease component
LLJ08_RS03790	COG0366	Alpha amylase catalytic
LLJ08_RS03795	COG3842	ATPase activity
LLJ08_RS03800	COG1280	lysine exporter protein (LysE YggA)
LLJ08_RS03825	COG1715	Restriction endonuclease
LLJ08_RS03835	COG0732	type I restriction modification DNA specificity domain
LLJ08_RS03865	COG0582	viral genome integration into host DNA
LLJ08_RS03890	COG1139	Iron-sulfur cluster binding protein
LLJ08_RS03895	COG0247	lactate metabolic process
LLJ08_RS03900	COG1620	l-lactate permease
LLJ08_RS03910	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LLJ08_RS03920	COG2914	Belongs to the UPF0125 (RnfH) family
LLJ08_RS03935	COG0497	DNA recombination
LLJ08_RS03940	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LLJ08_RS03945	COG0443	Heat shock 70 kDa protein
LLJ08_RS03950	COG0484	heat shock protein binding
LLJ08_RS03955	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LLJ08_RS03960	COG0505	Belongs to the CarA family
LLJ08_RS03990	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LLJ08_RS03995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LLJ08_RS04000	COG0149	triose-phosphate isomerase activity
LLJ08_RS04005	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LLJ08_RS04020	COG0779	Required for maturation of 30S ribosomal subunits
LLJ08_RS04025	COG0195	Participates in both transcription termination and antitermination
LLJ08_RS04030	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LLJ08_RS04035	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LLJ08_RS04040	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LLJ08_RS04045	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LLJ08_RS04050	COG1185	polyribonucleotide nucleotidyltransferase activity
LLJ08_RS04075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LLJ08_RS04085	COG0166	Belongs to the GPI family
LLJ08_RS04090	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LLJ08_RS04095	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LLJ08_RS04100	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LLJ08_RS04120	COG4191	Histidine kinase
LLJ08_RS04130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LLJ08_RS04135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LLJ08_RS04140	COG0436	Aminotransferase
LLJ08_RS04155	COG0679	Auxin Efflux Carrier
LLJ08_RS04170	COG2205	protein histidine kinase activity
LLJ08_RS04170	COG5002	protein histidine kinase activity
LLJ08_RS04170	COG0784	Response regulator, receiver
LLJ08_RS04180	COG0138	bifunctional purine biosynthesis protein purh
LLJ08_RS04200	COG2264	protein methyltransferase activity
LLJ08_RS04215	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LLJ08_RS04230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLJ08_RS04265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LLJ08_RS04285	COG0028	Belongs to the TPP enzyme family
LLJ08_RS04295	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LLJ08_RS04300	COG1183	phosphatidylcholine synthase activity
LLJ08_RS04310	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LLJ08_RS04340	COG2995	paraquat-inducible protein a
LLJ08_RS04345	COG2995	paraquat-inducible protein a
LLJ08_RS04350	COG3008	intermembrane lipid transfer
LLJ08_RS04370	COG0019	diaminopimelate decarboxylase activity
LLJ08_RS04380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LLJ08_RS04390	COG0456	acetyltransferase
LLJ08_RS04400	COG1877	trehalose-phosphatase activity
LLJ08_RS04405	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LLJ08_RS04410	COG0288	reversible hydration of carbon dioxide
LLJ08_RS04415	COG0697	spore germination
LLJ08_RS04430	COG4974	Belongs to the 'phage' integrase family
LLJ08_RS04520	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LLJ08_RS04535	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LLJ08_RS04545	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LLJ08_RS04550	COG0789	Transcriptional regulator
LLJ08_RS04585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LLJ08_RS04590	COG1960	acyl-CoA dehydrogenase activity
LLJ08_RS04595	COG4294	response to UV
LLJ08_RS04600	COG0318	PFAM AMP-dependent synthetase and ligase
LLJ08_RS04630	COG0559	Belongs to the binding-protein-dependent transport system permease family
LLJ08_RS04655	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LLJ08_RS04675	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LLJ08_RS04680	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LLJ08_RS04690	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LLJ08_RS04695	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LLJ08_RS04705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LLJ08_RS04710	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LLJ08_RS04730	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LLJ08_RS04735	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LLJ08_RS04775	COG0653	protein targeting
LLJ08_RS04780	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LLJ08_RS04790	COG0494	nUDIX hydrolase
LLJ08_RS04820	COG2096	Adenosyltransferase
LLJ08_RS04835	COG0745	RESPONSE REGULATOR receiver
LLJ08_RS04840	COG1666	GTP binding
LLJ08_RS04845	COG0668	transmembrane transport
LLJ08_RS04855	COG3695	enzyme binding
LLJ08_RS04865	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS04875	COG3030	protein affecting phage T7 exclusion by the F plasmid
LLJ08_RS04885	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LLJ08_RS04890	COG0459	protein refolding
LLJ08_RS04900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LLJ08_RS04905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LLJ08_RS04935	COG1704	LemA family
LLJ08_RS04960	COG1279	arginine transmembrane transporter activity
LLJ08_RS04965	COG0583	DNA-binding transcription factor activity
LLJ08_RS04985	COG3706	GGDEF domain
LLJ08_RS04990	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LLJ08_RS05005	COG1017	nitric oxide dioxygenase activity
LLJ08_RS05005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LLJ08_RS05015	COG0469	pyruvate kinase activity
LLJ08_RS05025	COG2084	Dehydrogenase
LLJ08_RS05030	COG3622	Belongs to the hyi family
LLJ08_RS05035	COG3960	tartronate-semialdehyde synthase activity
LLJ08_RS05040	COG0583	DNA-binding transcription factor activity
LLJ08_RS05045	COG2351	hydroxyisourate hydrolase activity
LLJ08_RS05070	COG3300	MHYT domain
LLJ08_RS05070	COG5001	Diguanylate cyclase
LLJ08_RS05090	COG2233	PERMEase
LLJ08_RS05095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LLJ08_RS05095	COG4651	solute:proton antiporter activity
LLJ08_RS05105	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LLJ08_RS05110	COG4266	Belongs to the allantoicase family
LLJ08_RS05135	COG2252	PERMEase
LLJ08_RS05140	COG1802	Transcriptional regulator
LLJ08_RS05145	COG1121	(ABC) transporter
LLJ08_RS05155	COG0803	Belongs to the bacterial solute-binding protein 9 family
LLJ08_RS05160	COG0402	S-adenosylhomocysteine deaminase activity
LLJ08_RS05200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LLJ08_RS05205	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LLJ08_RS05225	COG2326	polyphosphate kinase activity
LLJ08_RS05230	COG3081	Nucleoid-associated protein
LLJ08_RS05250	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LLJ08_RS05255	COG0477	Major facilitator Superfamily
LLJ08_RS05260	COG0471	metal ion transport
LLJ08_RS05260	COG0490	domain, Protein
LLJ08_RS05290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LLJ08_RS05295	COG0795	lipopolysaccharide-transporting ATPase activity
LLJ08_RS05300	COG0795	lipopolysaccharide-transporting ATPase activity
LLJ08_RS05310	COG1278	Cold shock
LLJ08_RS05320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LLJ08_RS05330	COG1862	Preprotein translocase
LLJ08_RS05345	COG3134	Outer membrane lipoprotein
LLJ08_RS05370	COG1104	cysteine desulfurase activity
LLJ08_RS05380	COG0316	Belongs to the HesB IscA family
LLJ08_RS05385	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LLJ08_RS05390	COG0443	Heat shock 70 kDa protein
LLJ08_RS05405	COG0105	UTP biosynthetic process
LLJ08_RS05410	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LLJ08_RS05425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LLJ08_RS05430	COG0124	histidyl-tRNA synthetase
LLJ08_RS05435	COG2976	Protein conserved in bacteria
LLJ08_RS05445	COG1160	GTP binding
LLJ08_RS05450	COG1045	serine acetyltransferase
LLJ08_RS05455	COG0436	Aminotransferase
LLJ08_RS05470	COG3647	Membrane
LLJ08_RS05475	COG2356	endonuclease I
LLJ08_RS05485	COG1064	alcohol dehydrogenase
LLJ08_RS05490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LLJ08_RS05505	COG0668	transmembrane transport
LLJ08_RS05515	COG0739	heme binding
LLJ08_RS05520	COG1570	exodeoxyribonuclease VII activity
LLJ08_RS05535	COG0519	Catalyzes the synthesis of GMP from XMP
LLJ08_RS05535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LLJ08_RS05545	COG0590	tRNA wobble adenosine to inosine editing
LLJ08_RS05550	COG3842	ATPase activity
LLJ08_RS05560	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LLJ08_RS05580	COG0556	nucleotide-excision repair
LLJ08_RS05585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LLJ08_RS05620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LLJ08_RS05650	COG3409	Peptidoglycan-binding domain 1 protein
LLJ08_RS05650	COG3267	Type II secretory pathway component ExeA
LLJ08_RS05665	COG1459	type II secretion system
LLJ08_RS05670	COG2165	general secretion pathway protein
LLJ08_RS05680	COG2165	general secretion pathway protein
LLJ08_RS05750	COG3639	organic phosphonate transmembrane transporter activity
LLJ08_RS05755	COG3639	organic phosphonate transmembrane transporter activity
LLJ08_RS05765	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LLJ08_RS05775	COG1968	undecaprenyl-diphosphatase activity
LLJ08_RS05780	COG2084	Dehydrogenase
LLJ08_RS05785	COG3622	Belongs to the hyi family
LLJ08_RS05790	COG2271	Major facilitator Superfamily
LLJ08_RS05795	COG0443	Heat shock 70 kDa protein
LLJ08_RS05805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LLJ08_RS05830	COG2030	dehydratase
LLJ08_RS05835	COG0318	PFAM AMP-dependent synthetase and ligase
LLJ08_RS05840	COG0318	PFAM AMP-dependent synthetase and ligase
LLJ08_RS05860	COG1643	Atp-dependent helicase
LLJ08_RS05875	COG0515	serine threonine protein kinase
LLJ08_RS05875	COG2815	serine threonine protein kinase
LLJ08_RS05880	COG0631	protein serine/threonine phosphatase activity
LLJ08_RS05885	COG2205	protein histidine kinase activity
LLJ08_RS05890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LLJ08_RS05895	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
LLJ08_RS05900	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LLJ08_RS05920	COG1234	tRNA 3'-trailer cleavage
LLJ08_RS05935	COG3795	YCII-related domain
LLJ08_RS05955	COG0537	adenosine 5'-monophosphoramidase activity
LLJ08_RS05960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LLJ08_RS05970	COG1116	anion transmembrane transporter activity
LLJ08_RS05975	COG2733	membrane
LLJ08_RS05995	COG1279	arginine transmembrane transporter activity
LLJ08_RS06020	COG0508	dehydrogenase complex catalyzes the overall conversion of
LLJ08_RS06020	COG0596	Alpha beta hydrolase
LLJ08_RS06030	COG2814	Major facilitator Superfamily
LLJ08_RS06060	COG0490	domain, Protein
LLJ08_RS06060	COG0471	metal ion transport
LLJ08_RS06070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LLJ08_RS06075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LLJ08_RS06085	COG1301	dicarboxylic acid transport
LLJ08_RS06105	COG1079	Belongs to the binding-protein-dependent transport system permease family
LLJ08_RS06110	COG4603	Belongs to the binding-protein-dependent transport system permease family
LLJ08_RS06115	COG3845	ABC transporter
LLJ08_RS06120	COG2207	Transcriptional regulator
LLJ08_RS06130	COG4221	oxidoreductase activity
LLJ08_RS06140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LLJ08_RS06150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LLJ08_RS06165	COG0784	Response regulator, receiver
LLJ08_RS06165	COG4191	Histidine kinase
LLJ08_RS06175	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LLJ08_RS06230	COG0583	DNA-binding transcription factor activity
LLJ08_RS06255	COG0095	Lipoate-protein ligase
LLJ08_RS06260	COG0508	dehydrogenase complex catalyzes the overall conversion of
LLJ08_RS06265	COG0508	dehydrogenase complex catalyzes the overall conversion of
LLJ08_RS06270	COG0022	dehydrogenase e1 component
LLJ08_RS06275	COG1063	alcohol dehydrogenase
LLJ08_RS06280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LLJ08_RS06295	COG3284	Transcriptional regulator
LLJ08_RS06305	COG0604	alcohol dehydrogenase
LLJ08_RS06305	COG3321	synthase
LLJ08_RS06310	COG0116	Belongs to the methyltransferase superfamily
LLJ08_RS06310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LLJ08_RS06320	COG1120	ATPase activity
LLJ08_RS06325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLJ08_RS06330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLJ08_RS06335	COG4771	TonB-dependent receptor
LLJ08_RS06350	COG4067	protein conserved in archaea
LLJ08_RS06350	COG0189	ligase activity
LLJ08_RS06360	COG1309	transcriptional regulator
LLJ08_RS06380	COG1462	curli production assembly transport component CsgG
LLJ08_RS06400	COG1280	lysine exporter protein (LysE YggA)
LLJ08_RS06410	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS06415	COG0583	DNA-binding transcription factor activity
LLJ08_RS06425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LLJ08_RS06435	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LLJ08_RS06445	COG3530	Putative quorum-sensing-regulated virulence factor
LLJ08_RS06455	COG2863	cytochrome
LLJ08_RS06460	COG3258	Cytochrome c
LLJ08_RS06475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LLJ08_RS06480	COG2171	N-acyltransferase activity
LLJ08_RS06485	COG1393	Belongs to the ArsC family
LLJ08_RS06505	COG0436	Aminotransferase
LLJ08_RS06520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LLJ08_RS06525	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LLJ08_RS06535	COG0628	permease
LLJ08_RS06540	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LLJ08_RS06555	COG1393	Belongs to the ArsC family
LLJ08_RS06560	COG1295	ribonuclease BN
LLJ08_RS06590	COG0442	prolyl-tRNA aminoacylation
LLJ08_RS06605	COG2900	Belongs to the SlyX family
LLJ08_RS06615	COG0783	Belongs to the Dps family
LLJ08_RS06620	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LLJ08_RS06630	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LLJ08_RS06635	COG0632	four-way junction helicase activity
LLJ08_RS06640	COG2255	four-way junction helicase activity
LLJ08_RS06645	COG0824	Thioesterase
LLJ08_RS06665	COG0823	Involved in the tonB-independent uptake of proteins
LLJ08_RS06670	COG2885	chlorophyll binding
LLJ08_RS06675	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LLJ08_RS06680	COG0602	queuosine metabolic process
LLJ08_RS06685	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LLJ08_RS06695	COG0427	acetyl-CoA hydrolase
LLJ08_RS06700	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LLJ08_RS06710	COG0425	Belongs to the sulfur carrier protein TusA family
LLJ08_RS06720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LLJ08_RS06725	COG2716	regulation of RNA biosynthetic process
LLJ08_RS06730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LLJ08_RS06740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LLJ08_RS06750	COG0417	DNA replication proofreading
LLJ08_RS06785	COG3174	membrane
LLJ08_RS06790	COG2205	protein histidine kinase activity
LLJ08_RS06810	COG2814	Major facilitator Superfamily
LLJ08_RS06815	COG2974	May be involved in recombination
LLJ08_RS06830	COG0545	Peptidyl-prolyl cis-trans isomerase
LLJ08_RS06850	COG1914	H( )-stimulated, divalent metal cation uptake system
LLJ08_RS06855	COG1984	allophanate hydrolase subunit 2
LLJ08_RS06860	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LLJ08_RS06865	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LLJ08_RS06875	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LLJ08_RS06880	COG3383	formate dehydrogenase (NAD+) activity
LLJ08_RS06885	COG1902	pentaerythritol trinitrate reductase activity
LLJ08_RS06900	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LLJ08_RS06940	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LLJ08_RS06945	COG0563	adenylate kinase activity
LLJ08_RS06970	COG0742	ribosomal rna small subunit methyltransferase
LLJ08_RS06980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LLJ08_RS06990	COG1309	transcriptional regulator
LLJ08_RS07010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LLJ08_RS07015	COG0348	domain, Protein
LLJ08_RS07020	COG1380	Effector of murein hydrolase LrgA
LLJ08_RS07025	COG1346	cytolysis
LLJ08_RS07035	COG1472	Belongs to the glycosyl hydrolase 3 family
LLJ08_RS07090	COG2132	Multicopper oxidase
LLJ08_RS07100	COG2217	Heavy metal translocating P-type atpase
LLJ08_RS07115	COG0642	Histidine kinase
LLJ08_RS07130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LLJ08_RS07160	COG3604	Transcriptional regulator
LLJ08_RS07170	COG0826	peptidase U32
LLJ08_RS07175	COG0826	peptidase U32
LLJ08_RS07180	COG3154	lipid carrier protein
LLJ08_RS07195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLJ08_RS07195	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LLJ08_RS07230	COG2814	Major facilitator Superfamily
LLJ08_RS07250	COG1737	Transcriptional regulator
LLJ08_RS07265	COG0800	Aldolase
LLJ08_RS07275	COG4989	oxidoreductase activity
LLJ08_RS07290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LLJ08_RS07300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LLJ08_RS07315	COG1805	sodium ion transport
LLJ08_RS07330	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LLJ08_RS07340	COG1477	protein flavinylation
LLJ08_RS07350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LLJ08_RS07355	COG0584	glycerophosphoryl diester phosphodiesterase
LLJ08_RS07370	COG4591	ABC-type transport system involved in lipoprotein release permease component
LLJ08_RS07375	COG1136	(ABC) transporter
LLJ08_RS07390	COG0658	competence protein
LLJ08_RS07390	COG2333	competence protein COMEC
LLJ08_RS07395	COG0811	peptide transport
LLJ08_RS07405	COG1663	tetraacyldisaccharide 4'-kinase activity
LLJ08_RS07410	COG2835	tetraacyldisaccharide 4'-kinase activity
LLJ08_RS07415	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LLJ08_RS07420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LLJ08_RS07425	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LLJ08_RS07430	COG1530	ribonuclease E activity
LLJ08_RS07440	COG0546	phosphoglycolate phosphatase activity
LLJ08_RS07445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LLJ08_RS07445	COG0616	signal peptide processing
LLJ08_RS07460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LLJ08_RS07465	COG0416	fatty acid biosynthetic process
LLJ08_RS07480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLJ08_RS07485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LLJ08_RS07495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LLJ08_RS07500	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LLJ08_RS07515	COG0084	hydrolase, TatD family'
LLJ08_RS07520	COG1113	amino acid transport
LLJ08_RS07565	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LLJ08_RS07580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LLJ08_RS07590	COG5001	Diguanylate cyclase
LLJ08_RS07605	COG2130	NADP-dependent
LLJ08_RS07615	COG3135	benzoate transporter
LLJ08_RS07620	COG1677	Flagellar hook-basal body complex protein FliE
LLJ08_RS07655	COG0745	RESPONSE REGULATOR receiver
LLJ08_RS07695	COG1987	bacterial-type flagellum assembly
LLJ08_RS07710	COG2032	superoxide dismutase activity
LLJ08_RS07740	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LLJ08_RS07745	COG0643	Histidine kinase
LLJ08_RS07745	COG0784	Response regulator, receiver
LLJ08_RS07745	COG2198	Histidine kinase
LLJ08_RS07750	COG2201	protein-glutamate methylesterase activity
LLJ08_RS07755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LLJ08_RS07760	COG1360	Flagellar Motor Protein
LLJ08_RS07765	COG1192	Involved in chromosome partitioning
LLJ08_RS07775	COG0835	chemotaxis
LLJ08_RS07790	COG2257	FlhB HrpN YscU SpaS Family
LLJ08_RS07820	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LLJ08_RS07870	COG0500	methyltransferase
LLJ08_RS07880	COG0501	Belongs to the peptidase M48B family
LLJ08_RS07890	COG0436	Aminotransferase
LLJ08_RS07895	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLJ08_RS07900	COG0386	Belongs to the glutathione peroxidase family
LLJ08_RS07955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLJ08_RS07975	COG1136	(ABC) transporter
LLJ08_RS07980	COG4591	ABC-type transport system involved in lipoprotein release permease component
LLJ08_RS08005	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
LLJ08_RS08020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LLJ08_RS08025	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LLJ08_RS08035	COG0840	transmembrane signaling receptor activity
LLJ08_RS08045	COG0776	regulation of translation
LLJ08_RS08055	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LLJ08_RS08055	COG0662	Cupin 2, conserved barrel domain protein
LLJ08_RS08065	COG1442	glycosyl transferase family 8
LLJ08_RS08065	COG1216	Glycosyl transferase, family 2
LLJ08_RS08095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LLJ08_RS08105	COG0438	transferase activity, transferring glycosyl groups
LLJ08_RS08135	COG2977	Belongs to the P-Pant transferase superfamily
LLJ08_RS08145	COG0183	Belongs to the thiolase family
LLJ08_RS08185	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LLJ08_RS08190	COG3206	protein involved in exopolysaccharide biosynthesis
LLJ08_RS08190	COG0489	protein tyrosine kinase activity
LLJ08_RS08195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LLJ08_RS08200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LLJ08_RS08210	COG3437	response regulator, receiver
LLJ08_RS08215	COG0633	Ferredoxin
LLJ08_RS08215	COG3217	Mosc domain protein beta barrel domain protein
LLJ08_RS08220	COG0741	lytic transglycosylase activity
LLJ08_RS08225	COG0488	(ABC) transporter
LLJ08_RS08235	COG0589	response to stress
LLJ08_RS08245	COG0121	glutamine amidotransferase
LLJ08_RS08265	COG0542	response to heat
LLJ08_RS08275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LLJ08_RS08285	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
LLJ08_RS08300	COG2832	Protein of unknown function (DUF454)
LLJ08_RS08320	COG1752	Esterase of the alpha-beta hydrolase superfamily
LLJ08_RS08355	COG2354	Protein conserved in bacteria
LLJ08_RS08360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LLJ08_RS08365	COG0727	PFAM Uncharacterised protein family (UPF0153)
LLJ08_RS08370	COG0778	Nitroreductase
LLJ08_RS08385	COG0745	RESPONSE REGULATOR receiver
LLJ08_RS08395	COG2350	Protein conserved in bacteria
LLJ08_RS08400	COG0613	PHP domain protein
LLJ08_RS08405	COG0009	L-threonylcarbamoyladenylate synthase
LLJ08_RS08410	COG0180	Tryptophanyl-tRNA synthetase
LLJ08_RS08420	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LLJ08_RS08450	COG1175	transmembrane transport
LLJ08_RS08455	COG0395	ABC-type sugar transport system, permease component
LLJ08_RS08460	COG3842	ATPase activity
LLJ08_RS08465	COG4580	involved in the transport of maltose and maltodextrins
LLJ08_RS08480	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LLJ08_RS08490	COG0235	Class ii aldolase
LLJ08_RS08495	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LLJ08_RS08500	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
LLJ08_RS08525	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LLJ08_RS08535	COG0583	DNA-binding transcription factor activity
LLJ08_RS08555	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LLJ08_RS08560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LLJ08_RS08580	COG0308	aminopeptidase N
LLJ08_RS08600	COG0243	molybdopterin cofactor binding
LLJ08_RS08605	COG2146	nitrite reductase [NAD(P)H] activity
LLJ08_RS08610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LLJ08_RS08620	COG0515	serine threonine protein kinase
LLJ08_RS08620	COG2815	serine threonine protein kinase
LLJ08_RS08625	COG2223	nitrite transmembrane transporter activity
LLJ08_RS08650	COG2197	response regulator
LLJ08_RS08655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LLJ08_RS08665	COG2304	oxidoreductase activity
LLJ08_RS08685	COG0714	Associated with various cellular activities
LLJ08_RS08705	COG0167	dihydroorotate dehydrogenase activity
LLJ08_RS08710	COG3130	regulation of translation
LLJ08_RS08715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LLJ08_RS08715	COG0116	Belongs to the methyltransferase superfamily
LLJ08_RS08720	COG2027	D-alanyl-D-alanine carboxypeptidase
LLJ08_RS08725	COG3171	Protein conserved in bacteria
LLJ08_RS08800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LLJ08_RS08810	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LLJ08_RS08815	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LLJ08_RS08820	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LLJ08_RS08825	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LLJ08_RS08830	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LLJ08_RS08835	COG0072	phenylalanine-tRNA ligase activity
LLJ08_RS08840	COG0776	regulation of translation
LLJ08_RS08855	COG2948	multi-organism process
LLJ08_RS08880	COG3451	type IV secretory pathway VirB4
LLJ08_RS08895	COG4962	Type ii secretion system protein e
LLJ08_RS08930	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LLJ08_RS08955	COG0583	DNA-binding transcription factor activity
LLJ08_RS08965	COG0367	asparagine synthase
LLJ08_RS08980	COG0156	8-amino-7-oxononanoate synthase activity
LLJ08_RS08985	COG3250	beta-galactosidase activity
LLJ08_RS09025	COG1392	Phosphate transport regulator
LLJ08_RS09055	COG2135	peptidase activity
LLJ08_RS09060	COG0587	DNA-directed DNA polymerase activity
LLJ08_RS09070	COG0784	Response regulator, receiver
LLJ08_RS09070	COG4191	Histidine kinase
LLJ08_RS09115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LLJ08_RS09125	COG1335	isochorismatase
LLJ08_RS09140	COG1126	abc transporter atp-binding protein
LLJ08_RS09145	COG0765	amino acid transport
LLJ08_RS09150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLJ08_RS09160	COG2197	response regulator
LLJ08_RS09180	COG0717	Belongs to the dCTP deaminase family
LLJ08_RS09205	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LLJ08_RS09295	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LLJ08_RS09360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LLJ08_RS09375	COG0477	Major facilitator Superfamily
LLJ08_RS09385	COG0789	Transcriptional regulator
LLJ08_RS09425	COG3192	ethanolamine utilization protein
LLJ08_RS09430	COG4303	Ethanolamine ammonia lyase large subunit
LLJ08_RS09440	COG3284	Transcriptional regulator
LLJ08_RS09445	COG1012	belongs to the aldehyde dehydrogenase family
LLJ08_RS09455	COG4772	TonB-dependent receptor
LLJ08_RS09460	COG0469	pyruvate kinase activity
LLJ08_RS09465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LLJ08_RS09480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLJ08_RS09485	COG2003	Belongs to the UPF0758 family
LLJ08_RS09495	COG5489	Protein of unknown function (DUF736)
LLJ08_RS09520	COG0587	DNA-directed DNA polymerase activity
LLJ08_RS09535	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LLJ08_RS09545	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LLJ08_RS09550	COG1605	Chorismate mutase
LLJ08_RS09550	COG0077	Prephenate dehydratase
LLJ08_RS09560	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LLJ08_RS09565	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LLJ08_RS09580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LLJ08_RS09585	COG0625	glutathione transferase activity
LLJ08_RS09590	COG0302	gtp cyclohydrolase
LLJ08_RS09595	COG2840	Smr protein MutS2
LLJ08_RS09620	COG0800	Aldolase
LLJ08_RS09630	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS09635	COG0546	phosphoglycolate phosphatase activity
LLJ08_RS09640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LLJ08_RS09645	COG0402	S-adenosylhomocysteine deaminase activity
LLJ08_RS09680	COG0720	synthase
LLJ08_RS09685	COG2056	Na+-H+ antiporter family
LLJ08_RS09690	COG0628	permease
LLJ08_RS09715	COG2153	protein acetylation
LLJ08_RS09720	COG2850	peptidyl-arginine hydroxylation
LLJ08_RS09730	COG2915	High frequency lysogenization protein hflD homolog
LLJ08_RS09735	COG0482	sulfurtransferase activity
LLJ08_RS09760	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LLJ08_RS09765	COG0542	response to heat
LLJ08_RS09770	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LLJ08_RS09775	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LLJ08_RS09780	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LLJ08_RS09785	COG0492	ferredoxin-NADP+ reductase activity
LLJ08_RS09795	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LLJ08_RS09800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LLJ08_RS09805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LLJ08_RS09810	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LLJ08_RS09815	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LLJ08_RS09815	COG1648	precorrin-2 dehydrogenase activity
LLJ08_RS09835	COG1131	(ABC) transporter
LLJ08_RS09855	COG0840	transmembrane signaling receptor activity
LLJ08_RS09865	COG3851	Histidine kinase
LLJ08_RS09920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LLJ08_RS09950	COG4172	Belongs to the ABC transporter superfamily
LLJ08_RS09955	COG4239	(ABC) transporter, permease
LLJ08_RS09960	COG4174	ABC transporter (Permease)
LLJ08_RS09970	COG4166	transmembrane transport
LLJ08_RS09980	COG0741	lytic transglycosylase activity
LLJ08_RS09980	COG1388	LysM domain
LLJ08_RS09985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LLJ08_RS09995	COG0328	RNA-DNA hybrid ribonuclease activity
LLJ08_RS10000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LLJ08_RS10010	COG1024	Enoyl-CoA hydratase
LLJ08_RS10020	COG2816	NAD+ diphosphatase activity
LLJ08_RS10025	COG0730	response to heat
LLJ08_RS10035	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS10055	COG0616	signal peptide processing
LLJ08_RS10060	COG0604	alcohol dehydrogenase
LLJ08_RS10080	COG0071	Belongs to the small heat shock protein (HSP20) family
LLJ08_RS10090	COG0515	serine threonine protein kinase
LLJ08_RS10095	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LLJ08_RS10100	COG2223	nitrite transmembrane transporter activity
LLJ08_RS10140	COG0316	Belongs to the HesB IscA family
LLJ08_RS10140	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LLJ08_RS10145	COG2197	response regulator
LLJ08_RS10150	COG3706	GGDEF domain
LLJ08_RS10165	COG2323	membrane
LLJ08_RS10180	COG0840	transmembrane signaling receptor activity
LLJ08_RS10185	COG1968	undecaprenyl-diphosphatase activity
LLJ08_RS10190	COG2267	carboxylic ester hydrolase activity
LLJ08_RS10195	COG0488	(ABC) transporter
LLJ08_RS10225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LLJ08_RS10230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LLJ08_RS10235	COG3265	gluconokinase activity
LLJ08_RS10240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LLJ08_RS10245	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LLJ08_RS10250	COG1609	Transcriptional regulator
LLJ08_RS10265	COG1070	Carbohydrate kinase
LLJ08_RS10285	COG1175	transmembrane transport
LLJ08_RS10320	COG0729	surface antigen
LLJ08_RS10325	COG2911	Protein conserved in bacteria
LLJ08_RS10330	COG1115	amino acid carrier protein
LLJ08_RS10345	COG0728	peptidoglycan biosynthetic process
LLJ08_RS10360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LLJ08_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS10395	COG3321	synthase
LLJ08_RS10395	COG0604	alcohol dehydrogenase
LLJ08_RS10400	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS10425	COG0366	Alpha amylase catalytic
LLJ08_RS10430	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LLJ08_RS10435	COG0392	lysyltransferase activity
LLJ08_RS10440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LLJ08_RS10445	COG3568	Endonuclease Exonuclease Phosphatase
LLJ08_RS10455	COG0583	DNA-binding transcription factor activity
LLJ08_RS10460	COG3384	dioxygenase
LLJ08_RS10470	COG0739	heme binding
LLJ08_RS10495	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LLJ08_RS10500	COG0297	glycogen (starch) synthase activity
LLJ08_RS10505	COG1058	Belongs to the CinA family
LLJ08_RS10505	COG1546	Belongs to the CinA family
LLJ08_RS10510	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LLJ08_RS10510	COG3264	Mechanosensitive ion channel
LLJ08_RS10515	COG3685	Protein conserved in bacteria
LLJ08_RS10555	COG0583	DNA-binding transcription factor activity
LLJ08_RS10625	COG0840	transmembrane signaling receptor activity
LLJ08_RS10650	COG5642	Protein of unknown function (DUF2384)
LLJ08_RS10675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LLJ08_RS10680	COG1742	UPF0060 membrane protein
LLJ08_RS10690	COG0431	NADPH-dependent FMN reductase
LLJ08_RS10695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LLJ08_RS10700	COG0640	Transcriptional regulator
LLJ08_RS10705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LLJ08_RS10710	COG2072	flavoprotein involved in K transport
LLJ08_RS10715	COG0798	PFAM Bile acid sodium symporter
LLJ08_RS10755	COG0322	excinuclease ABC activity
LLJ08_RS10770	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LLJ08_RS10775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LLJ08_RS10790	COG0784	Response regulator, receiver
LLJ08_RS10790	COG2205	protein histidine kinase activity
LLJ08_RS10805	COG0535	radical SAM domain protein
LLJ08_RS10815	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
LLJ08_RS10820	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LLJ08_RS10860	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LLJ08_RS10870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LLJ08_RS10880	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LLJ08_RS10885	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LLJ08_RS10895	COG0544	peptidyl-prolyl cis-trans isomerase activity
LLJ08_RS10905	COG0714	Associated with various cellular activities
LLJ08_RS10910	COG3256	nitric oxide reductase
LLJ08_RS10915	COG2010	Cytochrome c
LLJ08_RS10925	COG1846	Transcriptional regulator
LLJ08_RS10930	COG1764	response to oxidative stress
LLJ08_RS10955	COG2186	Transcriptional regulator
LLJ08_RS10980	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LLJ08_RS10985	COG0215	cysteine-tRNA ligase activity
LLJ08_RS10990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LLJ08_RS10995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LLJ08_RS11000	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LLJ08_RS11035	COG0668	transmembrane transport
LLJ08_RS11050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LLJ08_RS11060	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LLJ08_RS11075	COG0372	Belongs to the citrate synthase family
LLJ08_RS11085	COG1802	Transcriptional regulator
LLJ08_RS11110	COG0560	Phosphoserine phosphatase
LLJ08_RS11125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LLJ08_RS11130	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LLJ08_RS11160	COG4181	ATPase activity
LLJ08_RS11165	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LLJ08_RS11180	COG5380	lipid catabolic process
LLJ08_RS11185	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LLJ08_RS11205	COG3842	ATPase activity
LLJ08_RS11210	COG3665	Urea carboxylase-associated protein
LLJ08_RS11220	COG4770	biotin carboxylase activity
LLJ08_RS11230	COG0668	transmembrane transport
LLJ08_RS11240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LLJ08_RS11250	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS11270	COG1335	isochorismatase
LLJ08_RS11285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LLJ08_RS11290	COG1116	anion transmembrane transporter activity
LLJ08_RS11295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LLJ08_RS11345	COG2920	part of a sulfur-relay system
LLJ08_RS11350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LLJ08_RS11355	COG0435	Glutathione S-transferase
LLJ08_RS11360	COG2205	protein histidine kinase activity
LLJ08_RS11360	COG0784	Response regulator, receiver
LLJ08_RS11375	COG1025	Belongs to the peptidase M16 family
LLJ08_RS11380	COG0789	Transcriptional regulator
LLJ08_RS11395	COG0302	gtp cyclohydrolase
LLJ08_RS11400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LLJ08_RS11420	COG1366	Belongs to the anti-sigma-factor antagonist family
LLJ08_RS11425	COG5001	Diguanylate cyclase
LLJ08_RS11430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LLJ08_RS11435	COG1090	epimerase
LLJ08_RS11440	COG3272	Protein of unknown function (DUF1722)
LLJ08_RS11445	COG0789	Transcriptional regulator
LLJ08_RS11450	COG0415	Belongs to the DNA photolyase family
LLJ08_RS11460	COG4221	oxidoreductase activity
LLJ08_RS11475	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LLJ08_RS11485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LLJ08_RS11495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LLJ08_RS11495	COG2146	nitrite reductase [NAD(P)H] activity
LLJ08_RS11500	COG2146	nitrite reductase [NAD(P)H] activity
LLJ08_RS11500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LLJ08_RS11510	COG0515	serine threonine protein kinase
LLJ08_RS11515	COG0210	DNA helicase
LLJ08_RS11565	COG3447	MASE1 domain protein
LLJ08_RS11565	COG5002	protein histidine kinase activity
LLJ08_RS11565	COG5001	Diguanylate cyclase
LLJ08_RS11580	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LLJ08_RS11600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LLJ08_RS11610	COG1253	flavin adenine dinucleotide binding
LLJ08_RS11615	COG4991	sh3 domain protein
LLJ08_RS11630	COG0058	SHG alpha-glucan phosphorylase activity
LLJ08_RS11640	COG2205	protein histidine kinase activity
LLJ08_RS11655	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LLJ08_RS11690	COG1024	Enoyl-CoA hydratase
LLJ08_RS11695	COG1960	acyl-CoA dehydrogenase activity
LLJ08_RS11705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LLJ08_RS11710	COG0318	PFAM AMP-dependent synthetase and ligase
LLJ08_RS11715	COG1960	acyl-CoA dehydrogenase activity
LLJ08_RS11735	COG1238	metal cluster binding
LLJ08_RS11755	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
LLJ08_RS11780	COG0714	Associated with various cellular activities
LLJ08_RS11790	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
LLJ08_RS11795	COG0709	Synthesizes selenophosphate from selenide and ATP
LLJ08_RS11805	COG0628	permease
LLJ08_RS11840	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LLJ08_RS11845	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LLJ08_RS11855	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LLJ08_RS11920	COG0045	succinate-CoA ligase (ADP-forming) activity
LLJ08_RS11940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LLJ08_RS11945	COG1053	succinate dehydrogenase
LLJ08_RS11950	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LLJ08_RS11955	COG2009	succinate dehydrogenase
LLJ08_RS12005	COG0457	Tetratricopeptide repeat
LLJ08_RS12005	COG0859	PFAM glycosyl transferase family 9
LLJ08_RS12015	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LLJ08_RS12020	COG3115	cell septum assembly
LLJ08_RS12030	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LLJ08_RS12035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLJ08_RS12050	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LLJ08_RS12050	COG2010	Cytochrome c
LLJ08_RS12055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LLJ08_RS12075	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LLJ08_RS12085	COG0840	transmembrane signaling receptor activity
LLJ08_RS12095	COG3278	Belongs to the heme-copper respiratory oxidase family
LLJ08_RS12105	COG2010	Cytochrome c
LLJ08_RS12110	COG3278	Belongs to the heme-copper respiratory oxidase family
LLJ08_RS12125	COG2010	Cytochrome c
LLJ08_RS12155	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LLJ08_RS12165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LLJ08_RS12185	COG0573	inorganic phosphate transmembrane transporter activity
LLJ08_RS12200	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LLJ08_RS12205	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LLJ08_RS12215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LLJ08_RS12230	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LLJ08_RS12245	COG0446	pyridine nucleotide-disulphide oxidoreductase
LLJ08_RS12245	COG1902	pentaerythritol trinitrate reductase activity
LLJ08_RS12265	COG1294	oxidase, subunit
LLJ08_RS12270	COG1271	oxidase subunit
LLJ08_RS12295	COG0655	NAD(P)H dehydrogenase (quinone) activity
LLJ08_RS12300	COG0583	DNA-binding transcription factor activity
LLJ08_RS12345	COG1286	toxin biosynthetic process
LLJ08_RS12355	COG0285	dihydrofolate synthase activity
LLJ08_RS12360	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LLJ08_RS12365	COG0135	phosphoribosylanthranilate isomerase activity
LLJ08_RS12390	COG0473	3-isopropylmalate dehydrogenase activity
LLJ08_RS12395	COG0066	3-isopropylmalate dehydratase activity
LLJ08_RS12400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LLJ08_RS12415	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS12480	COG0250	Participates in transcription elongation, termination and antitermination
LLJ08_RS12510	COG0297	glycogen (starch) synthase activity
LLJ08_RS12525	COG1216	Glycosyl transferase, family 2
LLJ08_RS12580	COG4964	Belongs to the GSP D family
LLJ08_RS12610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LLJ08_RS12615	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LLJ08_RS12620	COG1012	belongs to the aldehyde dehydrogenase family
LLJ08_RS12625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LLJ08_RS12630	COG0133	tryptophan synthase activity
LLJ08_RS12650	COG0653	protein targeting
LLJ08_RS12680	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LLJ08_RS12715	COG0183	Belongs to the thiolase family
LLJ08_RS12720	COG1250	3-hydroxyacyl-CoA dehydrogenase
LLJ08_RS12720	COG1024	Enoyl-CoA hydratase
LLJ08_RS12725	COG1770	oligopeptidase
LLJ08_RS12735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LLJ08_RS12745	COG0583	DNA-binding transcription factor activity
LLJ08_RS12750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LLJ08_RS12755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LLJ08_RS12760	COG3755	Protein conserved in bacteria
LLJ08_RS12785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LLJ08_RS12790	COG2079	MmgE PrpD family protein
LLJ08_RS12800	COG1960	acyl-CoA dehydrogenase activity
LLJ08_RS12805	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LLJ08_RS12810	COG0583	DNA-binding transcription factor activity
LLJ08_RS12835	COG0840	transmembrane signaling receptor activity
LLJ08_RS12840	COG1132	(ABC) transporter
LLJ08_RS12850	COG1054	Belongs to the UPF0176 family
LLJ08_RS12855	COG0271	Belongs to the BolA IbaG family
LLJ08_RS12865	COG0114	fumarate hydratase activity
LLJ08_RS12900	COG3135	benzoate transporter
LLJ08_RS12905	COG3485	protocatechuate 3,4-dioxygenase
LLJ08_RS12910	COG4829	muconolactone delta-isomerase
LLJ08_RS12915	COG4948	Mandelate Racemase Muconate Lactonizing
LLJ08_RS12920	COG2814	Major facilitator Superfamily
LLJ08_RS12955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LLJ08_RS12965	COG0745	RESPONSE REGULATOR receiver
LLJ08_RS12975	COG2853	Lipoprotein
LLJ08_RS12985	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LLJ08_RS12985	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LLJ08_RS12990	COG0842	Transport permease protein
LLJ08_RS12995	COG1131	(ABC) transporter
LLJ08_RS13000	COG2988	succinylglutamate desuccinylase activity
LLJ08_RS13010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LLJ08_RS13045	COG0668	transmembrane transport
LLJ08_RS13060	COG1793	dna ligase
LLJ08_RS13065	COG1201	RNA secondary structure unwinding
LLJ08_RS13095	COG3956	TIGRFAM MazG family protein
LLJ08_RS13100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LLJ08_RS13105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LLJ08_RS13120	COG2860	membrane
LLJ08_RS13125	COG5002	protein histidine kinase activity
LLJ08_RS13125	COG2205	protein histidine kinase activity
LLJ08_RS13125	COG0784	Response regulator, receiver
LLJ08_RS13130	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LLJ08_RS13130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LLJ08_RS13150	COG0583	DNA-binding transcription factor activity
LLJ08_RS13165	COG0513	Belongs to the DEAD box helicase family
LLJ08_RS13205	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LLJ08_RS13210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LLJ08_RS13215	COG2226	methyltransferase
LLJ08_RS13225	COG1278	Cold shock
LLJ08_RS13240	COG1131	(ABC) transporter
LLJ08_RS13270	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LLJ08_RS13275	COG2937	Belongs to the GPAT DAPAT family
LLJ08_RS13290	COG2205	protein histidine kinase activity
LLJ08_RS13295	COG0745	RESPONSE REGULATOR receiver
LLJ08_RS13300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLJ08_RS13300	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LLJ08_RS13305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLJ08_RS13330	COG1943	Transposase
LLJ08_RS13340	COG0583	DNA-binding transcription factor activity
LLJ08_RS13345	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LLJ08_RS13360	COG1846	Transcriptional regulator
LLJ08_RS13365	COG2807	transmembrane transport
LLJ08_RS13375	COG2226	methyltransferase
LLJ08_RS13405	COG2249	NAD(P)H dehydrogenase (quinone) activity
LLJ08_RS13410	COG0583	DNA-binding transcription factor activity
LLJ08_RS13415	COG1733	regulation of RNA biosynthetic process
LLJ08_RS13470	COG3459	Glycosyltransferase 36 associated
LLJ08_RS13480	COG0826	peptidase U32
LLJ08_RS13490	COG2814	Major facilitator Superfamily
LLJ08_RS13495	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS13510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LLJ08_RS13535	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LLJ08_RS13560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LLJ08_RS13590	COG0483	inositol monophosphate 1-phosphatase activity
LLJ08_RS13615	COG0004	ammonium transporteR
LLJ08_RS13630	COG2258	MOSC domain
LLJ08_RS13645	COG0217	transcriptional regulatory protein
LLJ08_RS13655	COG0589	response to stress
LLJ08_RS13665	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LLJ08_RS13710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LLJ08_RS13715	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LLJ08_RS13720	COG0585	pseudouridine synthase activity
LLJ08_RS13725	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LLJ08_RS13735	COG1902	pentaerythritol trinitrate reductase activity
LLJ08_RS13740	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LLJ08_RS13745	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LLJ08_RS13750	COG0583	DNA-binding transcription factor activity
LLJ08_RS13765	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LLJ08_RS13775	COG0148	phosphopyruvate hydratase activity
LLJ08_RS13780	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LLJ08_RS13785	COG0504	CTP synthase activity
LLJ08_RS13790	COG0037	tRNA processing
LLJ08_RS13795	COG0825	malonyl-CoA metabolic process
LLJ08_RS13805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LLJ08_RS13810	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LLJ08_RS13815	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LLJ08_RS13820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LLJ08_RS13835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LLJ08_RS13845	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LLJ08_RS13855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LLJ08_RS13860	COG0233	cytoplasmic translational termination
LLJ08_RS13865	COG0528	UMP kinase activity
LLJ08_RS13870	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LLJ08_RS13875	COG0052	Belongs to the universal ribosomal protein uS2 family
LLJ08_RS13880	COG0024	Methionine aminopeptidase
LLJ08_RS13885	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LLJ08_RS13890	COG1320	monovalent cation:proton antiporter activity
LLJ08_RS13895	COG2212	antiporter activity
LLJ08_RS13900	COG1863	multisubunit Na H antiporter MnhE subunit
LLJ08_RS13905	COG0651	ATP synthesis coupled electron transport
LLJ08_RS13910	COG1006	Multisubunit Na H antiporter MnhC subunit
LLJ08_RS13915	COG2111	Na H antiporter
LLJ08_RS13915	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LLJ08_RS13920	COG3133	Outer membrane lipoprotein
LLJ08_RS13930	COG0259	pyridoxamine-phosphate oxidase activity
LLJ08_RS13940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LLJ08_RS13945	COG1199	ATP-dependent helicase activity
LLJ08_RS13965	COG3012	SEC-C Motif Domain Protein
LLJ08_RS13985	COG0697	spore germination
LLJ08_RS13990	COG3148	PFAM DTW domain containing protein
LLJ08_RS14000	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LLJ08_RS14005	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LLJ08_RS14015	COG2137	regulation of response to DNA damage stimulus
LLJ08_RS14020	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LLJ08_RS14025	COG1546	Belongs to the CinA family
LLJ08_RS14035	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LLJ08_RS14040	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LLJ08_RS14065	COG1295	ribonuclease BN
LLJ08_RS14075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LLJ08_RS14095	COG3842	ATPase activity
LLJ08_RS14115	COG5002	protein histidine kinase activity
LLJ08_RS14115	COG2198	Histidine kinase
LLJ08_RS14115	COG0784	Response regulator, receiver
LLJ08_RS14130	COG1696	Membrane protein involved in D-alanine export
LLJ08_RS14140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLJ08_RS14155	COG3284	Transcriptional regulator
LLJ08_RS14200	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LLJ08_RS14215	COG2996	Protein conserved in bacteria
LLJ08_RS14220	COG4993	Dehydrogenase
LLJ08_RS14225	COG2133	pyrroloquinoline quinone binding
LLJ08_RS14235	COG1187	pseudouridine synthase activity
LLJ08_RS14260	COG1201	RNA secondary structure unwinding
LLJ08_RS14270	COG4221	oxidoreductase activity
LLJ08_RS14280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LLJ08_RS14290	COG1404	Belongs to the peptidase S8 family
LLJ08_RS14290	COG4935	Belongs to the peptidase S8 family
LLJ08_RS14300	COG0367	asparagine synthase
LLJ08_RS14305	COG0189	ligase activity
LLJ08_RS14305	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LLJ08_RS14310	COG1363	Peptidase, m42
LLJ08_RS14320	COG3089	Belongs to the UPF0270 family
LLJ08_RS14340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LLJ08_RS14345	COG3162	membrane
LLJ08_RS14360	COG2853	Lipoprotein
LLJ08_RS14370	COG1560	Kdo2-lipid A biosynthetic process
LLJ08_RS14375	COG0850	regulation of cytokinetic process
LLJ08_RS14380	COG2894	cell division
LLJ08_RS14385	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LLJ08_RS14390	COG0564	pseudouridine synthase activity
LLJ08_RS14395	COG1362	aminopeptidase activity
LLJ08_RS14410	COG2200	EAL domain
LLJ08_RS14410	COG2199	diguanylate cyclase activity
LLJ08_RS14435	COG1555	photosystem II stabilization
LLJ08_RS14445	COG1256	bacterial-type flagellum assembly
LLJ08_RS14455	COG1706	bacterial-type flagellum-dependent cell motility
LLJ08_RS14460	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LLJ08_RS14465	COG4786	Flagellar basal body rod
LLJ08_RS14470	COG4787	bacterial-type flagellum-dependent cell motility
LLJ08_RS14490	COG1815	bacterial-type flagellum-dependent cell motility
LLJ08_RS14495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LLJ08_RS14500	COG0784	Response regulator, receiver
LLJ08_RS14500	COG0835	chemotaxis
LLJ08_RS14520	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LLJ08_RS14545	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
LLJ08_RS14550	COG5016	pyruvate
LLJ08_RS14550	COG0511	ligase activity, forming carbon-carbon bonds
LLJ08_RS14555	COG3630	sodium ion export across plasma membrane
LLJ08_RS14560	COG2239	Acts as a magnesium transporter
LLJ08_RS14585	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LLJ08_RS14590	COG0527	aspartate kinase activity
LLJ08_RS14595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LLJ08_RS14610	COG2983	Belongs to the UPF0260 family
LLJ08_RS14620	COG3100	YcgL domain-containing protein
LLJ08_RS14635	COG2067	long-chain fatty acid transport protein
LLJ08_RS14660	COG0251	oxidation-reduction process
LLJ08_RS14670	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LLJ08_RS14675	COG0406	alpha-ribazole phosphatase activity
LLJ08_RS14680	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LLJ08_RS14690	COG1492	cobalamin metabolic process
LLJ08_RS14700	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LLJ08_RS14710	COG0778	Nitroreductase
LLJ08_RS14715	COG1797	cobyrinic acid a,c-diamide synthase activity
LLJ08_RS14730	COG4206	TonB-dependent receptor
LLJ08_RS14745	COG0791	NLP P60 protein
LLJ08_RS14750	COG0791	NLP P60 protein
LLJ08_RS14765	COG4890	Cyd operon protein YbgT
LLJ08_RS14770	COG1294	oxidase, subunit
LLJ08_RS14800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LLJ08_RS14805	COG0037	tRNA processing
LLJ08_RS14825	COG3091	SprT-like family
LLJ08_RS14830	COG2814	Major facilitator Superfamily
LLJ08_RS14835	COG4459	periplasmic nitrate reductase
LLJ08_RS14845	COG0243	molybdopterin cofactor binding
LLJ08_RS14855	COG3005	denitrification pathway
LLJ08_RS14860	COG0717	Belongs to the dCTP deaminase family
LLJ08_RS14865	COG1278	Cold shock
LLJ08_RS14870	COG0489	protein tyrosine kinase activity
LLJ08_RS14875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLJ08_RS14875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLJ08_RS14895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LLJ08_RS14905	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LLJ08_RS14910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LLJ08_RS14915	COG1414	Transcriptional regulator
LLJ08_RS14935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LLJ08_RS14950	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LLJ08_RS14965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LLJ08_RS14975	COG2226	methyltransferase
LLJ08_RS14980	COG0500	methyltransferase
LLJ08_RS14990	COG0583	DNA-binding transcription factor activity
LLJ08_RS15000	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LLJ08_RS15005	COG1381	Involved in DNA repair and RecF pathway recombination
LLJ08_RS15015	COG0571	ribonuclease III activity
LLJ08_RS15030	COG0481	GTPase activity
LLJ08_RS15035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LLJ08_RS15075	COG0354	folic acid binding
LLJ08_RS15090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LLJ08_RS15100	COG1024	Enoyl-CoA hydratase
LLJ08_RS15115	COG4657	Part of a membrane complex involved in electron transport
LLJ08_RS15120	COG2878	Part of a membrane complex involved in electron transport
LLJ08_RS15130	COG4658	electron transport chain
LLJ08_RS15135	COG4659	FMN binding
LLJ08_RS15145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LLJ08_RS15155	COG0346	lactoylglutathione lyase activity
LLJ08_RS15160	COG0137	argininosuccinate synthase activity
LLJ08_RS15170	COG0418	dihydroorotase activity
LLJ08_RS15175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LLJ08_RS15190	COG3791	Glutathione-dependent formaldehyde-activating
LLJ08_RS15200	COG4974	Belongs to the 'phage' integrase family
LLJ08_RS15205	COG0335	large ribosomal subunit rRNA binding
LLJ08_RS15210	COG0336	Belongs to the RNA methyltransferase TrmD family
LLJ08_RS15215	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LLJ08_RS15220	COG0228	four-way junction DNA binding
LLJ08_RS15225	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LLJ08_RS15230	COG4137	Cytochrome C assembly protein
LLJ08_RS15235	COG4536	flavin adenine dinucleotide binding
LLJ08_RS15240	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LLJ08_RS15265	COG3034	peptidoglycan biosynthetic process
LLJ08_RS15275	COG0047	phosphoribosylformylglycinamidine synthase activity
LLJ08_RS15275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LLJ08_RS15280	COG1126	abc transporter atp-binding protein
LLJ08_RS15285	COG0765	amino acid transport
LLJ08_RS15290	COG4597	amino acid ABC transporter
LLJ08_RS15295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LLJ08_RS15300	COG0400	carboxylic ester hydrolase activity
LLJ08_RS15320	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LLJ08_RS15325	COG0315	cyclic pyranopterin monophosphate synthase activity
LLJ08_RS15330	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LLJ08_RS15335	COG1230	cation diffusion facilitator family transporter
LLJ08_RS15340	COG3022	response to hydroperoxide
LLJ08_RS15350	COG0662	Cupin 2, conserved barrel domain protein
LLJ08_RS15350	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LLJ08_RS15360	COG0433	COG0433 Predicted ATPase
LLJ08_RS15370	COG0788	formyltetrahydrofolate deformylase activity
LLJ08_RS15380	COG2925	Exonuclease
LLJ08_RS15405	COG0714	Associated with various cellular activities
LLJ08_RS15440	COG3706	GGDEF domain
LLJ08_RS15450	COG0840	transmembrane signaling receptor activity
LLJ08_RS15455	COG4628	conserved protein (DUF2132)
LLJ08_RS15460	COG0693	protein deglycase activity
LLJ08_RS15465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LLJ08_RS15510	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LLJ08_RS15525	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LLJ08_RS15535	COG1309	transcriptional regulator
LLJ08_RS15540	COG0386	Belongs to the glutathione peroxidase family
LLJ08_RS15550	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LLJ08_RS15560	COG0204	Acyl-transferase
LLJ08_RS15570	COG2205	protein histidine kinase activity
LLJ08_RS15570	COG0784	Response regulator, receiver
LLJ08_RS15575	COG2885	chlorophyll binding
LLJ08_RS15580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LLJ08_RS15585	COG0318	PFAM AMP-dependent synthetase and ligase
LLJ08_RS15590	COG1280	lysine exporter protein (LysE YggA)
LLJ08_RS15595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LLJ08_RS15600	COG2813	Specifically methylates the guanine in position
LLJ08_RS15605	COG2119	membrane
LLJ08_RS15615	COG0501	Belongs to the peptidase M48B family
LLJ08_RS15620	COG0840	transmembrane signaling receptor activity
LLJ08_RS15675	COG0659	secondary active sulfate transmembrane transporter activity
LLJ08_RS15680	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS15705	COG1285	pathogenesis
LLJ08_RS15750	COG1181	Belongs to the D-alanine--D-alanine ligase family
LLJ08_RS15755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LLJ08_RS15760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LLJ08_RS15765	COG0772	Belongs to the SEDS family
LLJ08_RS15770	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LLJ08_RS15775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LLJ08_RS15780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LLJ08_RS15785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LLJ08_RS15800	COG0275	rRNA processing
LLJ08_RS15825	COG0792	nuclease activity
LLJ08_RS15830	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LLJ08_RS15835	COG2823	Periplasmic or secreted lipoprotein
LLJ08_RS15840	COG2969	positive regulation of protein catabolic process
LLJ08_RS15845	COG0625	glutathione transferase activity
LLJ08_RS15850	COG2857	Cytochrome c1
LLJ08_RS15855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LLJ08_RS15860	COG0723	plastoquinol--plastocyanin reductase activity
LLJ08_RS15865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LLJ08_RS15870	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LLJ08_RS15875	COG0667	Aldo Keto reductase
LLJ08_RS15890	COG0237	dephospho-CoA kinase activity
LLJ08_RS15895	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LLJ08_RS15925	COG0175	sulfate reduction
LLJ08_RS15935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LLJ08_RS15940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LLJ08_RS15950	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LLJ08_RS15955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LLJ08_RS15980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LLJ08_RS15985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LLJ08_RS15990	COG1127	ABC transporter
LLJ08_RS16000	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LLJ08_RS16015	COG1137	ATPase activity
LLJ08_RS16020	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LLJ08_RS16035	COG1660	Displays ATPase and GTPase activities
LLJ08_RS16045	COG0312	modulator of DNA gyrase
LLJ08_RS16055	COG0312	modulator of DNA gyrase
LLJ08_RS16060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LLJ08_RS16070	COG1530	ribonuclease E activity
LLJ08_RS16090	COG1792	Involved in formation and maintenance of cell shape
LLJ08_RS16095	COG1077	Cell shape determining protein MreB Mrl
LLJ08_RS16110	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LLJ08_RS16115	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LLJ08_RS16125	COG0530	calcium, potassium:sodium antiporter activity
LLJ08_RS16140	COG0739	heme binding
LLJ08_RS16150	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LLJ08_RS16165	COG4771	TonB-dependent receptor
LLJ08_RS16185	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LLJ08_RS16190	COG4774	siderophore transport
LLJ08_RS16195	COG3128	pkhd-type hydroxylase
LLJ08_RS16205	COG0019	diaminopimelate decarboxylase activity
LLJ08_RS16210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LLJ08_RS16215	COG2852	Protein conserved in bacteria
LLJ08_RS16220	COG4993	Dehydrogenase
LLJ08_RS16225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LLJ08_RS16225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LLJ08_RS16225	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LLJ08_RS16230	COG1105	Belongs to the carbohydrate kinase PfkB family
LLJ08_RS16235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LLJ08_RS16235	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LLJ08_RS16250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LLJ08_RS16280	COG0534	Mate efflux family protein
LLJ08_RS16290	COG1166	arginine decarboxylase activity
LLJ08_RS16295	COG0023	Translation Initiation Factor
LLJ08_RS16300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LLJ08_RS16305	COG4968	Prepilin-type N-terminal cleavage methylation domain
LLJ08_RS16310	COG4969	Belongs to the N-Me-Phe pilin family
LLJ08_RS16340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LLJ08_RS16345	COG1047	Peptidyl-prolyl cis-trans
LLJ08_RS16350	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LLJ08_RS16355	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LLJ08_RS16360	COG0196	riboflavin kinase activity
LLJ08_RS16370	COG0268	Binds directly to 16S ribosomal RNA
LLJ08_RS16375	COG3045	CreA protein
LLJ08_RS16380	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LLJ08_RS16385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LLJ08_RS16390	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LLJ08_RS16395	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LLJ08_RS16400	COG0142	geranyltranstransferase activity
LLJ08_RS16410	COG0545	Peptidyl-prolyl cis-trans isomerase
LLJ08_RS16420	COG3046	protein related to deoxyribodipyrimidine photolyase
LLJ08_RS16430	COG2862	Uncharacterized protein family, UPF0114
LLJ08_RS16440	COG1067	ATP-dependent peptidase activity
LLJ08_RS16450	COG1970	mechanosensitive ion channel activity
LLJ08_RS16480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LLJ08_RS16485	COG0488	(ABC) transporter
LLJ08_RS16520	COG2813	Specifically methylates the guanine in position
LLJ08_RS16525	COG0789	Transcriptional regulator
LLJ08_RS16535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LLJ08_RS16540	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LLJ08_RS16545	COG2080	2 iron, 2 sulfur cluster binding
LLJ08_RS16555	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LLJ08_RS16555	COG3608	succinylglutamate desuccinylase aspartoacylase
LLJ08_RS16565	COG2252	PERMEase
LLJ08_RS16570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LLJ08_RS16575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LLJ08_RS16580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LLJ08_RS16610	COG3642	lipopolysaccharide core region biosynthetic process
LLJ08_RS16665	COG3038	cytochrome b561
LLJ08_RS16670	COG0303	'Molybdopterin
LLJ08_RS16675	COG0521	Mo-molybdopterin cofactor biosynthetic process
LLJ08_RS16690	COG2181	nitrate reductase activity
LLJ08_RS16695	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LLJ08_RS16700	COG1140	nitrate reductase beta subunit
LLJ08_RS16705	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LLJ08_RS16710	COG2223	nitrite transmembrane transporter activity
LLJ08_RS16725	COG3850	Histidine kinase
LLJ08_RS16730	COG2197	response regulator
LLJ08_RS16755	COG2321	neutral zinc metallopeptidase
LLJ08_RS16765	COG1946	Acyl-CoA thioesterase
LLJ08_RS16775	COG0123	including yeast histone deacetylase and acetoin utilization protein
LLJ08_RS16800	COG0513	Belongs to the DEAD box helicase family
LLJ08_RS16805	COG4651	solute:proton antiporter activity
LLJ08_RS16805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LLJ08_RS16825	COG0733	neurotransmitter:sodium symporter activity
LLJ08_RS16830	COG0625	glutathione transferase activity
LLJ08_RS16840	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LLJ08_RS16850	COG0733	neurotransmitter:sodium symporter activity
LLJ08_RS16865	COG1522	sequence-specific DNA binding
LLJ08_RS16875	COG2031	fatty acid transporter
LLJ08_RS16880	COG2610	gluconate transmembrane transporter activity
LLJ08_RS16885	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS16900	COG0564	pseudouridine synthase activity
LLJ08_RS16950	COG0420	3'-5' exonuclease activity
LLJ08_RS16960	COG4206	TonB-dependent receptor
LLJ08_RS16975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LLJ08_RS16980	COG3577	Aspartyl protease
LLJ08_RS16985	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LLJ08_RS16990	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LLJ08_RS16995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LLJ08_RS17000	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LLJ08_RS17015	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LLJ08_RS17015	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LLJ08_RS17030	COG2264	protein methyltransferase activity
LLJ08_RS17040	COG0425	Belongs to the sulfur carrier protein TusA family
LLJ08_RS17045	COG2391	methyltransferase activity
LLJ08_RS17050	COG3118	belongs to the thioredoxin family
LLJ08_RS17065	COG4181	ATPase activity
LLJ08_RS17090	COG0848	biopolymer transport protein
LLJ08_RS17095	COG0811	peptide transport
LLJ08_RS17100	COG0811	peptide transport
LLJ08_RS17110	COG3047	cAMP biosynthetic process
LLJ08_RS17115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LLJ08_RS17130	COG2814	Major facilitator Superfamily
LLJ08_RS17145	COG0753	catalase activity
LLJ08_RS17150	COG0203	ribosomal protein L17
LLJ08_RS17155	COG0202	RNA polymerase activity
LLJ08_RS17160	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LLJ08_RS17165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LLJ08_RS17170	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LLJ08_RS17175	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LLJ08_RS17185	COG0200	Binds to the 23S rRNA
LLJ08_RS17190	COG1841	ribosomal large subunit assembly
LLJ08_RS17195	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LLJ08_RS17205	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LLJ08_RS17210	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LLJ08_RS17215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LLJ08_RS17220	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LLJ08_RS17225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LLJ08_RS17230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LLJ08_RS17235	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LLJ08_RS17240	COG0255	Belongs to the universal ribosomal protein uL29 family
LLJ08_RS17245	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LLJ08_RS17250	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LLJ08_RS17255	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LLJ08_RS17260	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LLJ08_RS17265	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LLJ08_RS17270	COG0089	rRNA binding
LLJ08_RS17275	COG0088	Forms part of the polypeptide exit tunnel
LLJ08_RS17280	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LLJ08_RS17285	COG0051	transcription antitermination factor activity, RNA binding
LLJ08_RS17290	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LLJ08_RS17295	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LLJ08_RS17300	COG0049	tRNA binding
LLJ08_RS17305	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LLJ08_RS17310	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LLJ08_RS17315	COG0085	RNA polymerase activity
LLJ08_RS17320	COG0222	ribosome binding
LLJ08_RS17330	COG0081	regulation of translation
LLJ08_RS17335	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LLJ08_RS17355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LLJ08_RS17380	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LLJ08_RS17385	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LLJ08_RS17385	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LLJ08_RS17420	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LLJ08_RS17425	COG0739	heme binding
LLJ08_RS17430	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LLJ08_RS17435	COG0316	Belongs to the HesB IscA family
LLJ08_RS17440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LLJ08_RS17445	COG1981	membrane
LLJ08_RS17455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LLJ08_RS17460	COG0537	adenosine 5'-monophosphoramidase activity
LLJ08_RS17465	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LLJ08_RS17475	COG1765	OsmC-like protein
LLJ08_RS17485	COG0134	indole-3-glycerol-phosphate synthase activity
LLJ08_RS17490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LLJ08_RS17495	COG0512	Glutamine amidotransferase of anthranilate synthase
LLJ08_RS17505	COG0546	phosphoglycolate phosphatase activity
LLJ08_RS17510	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LLJ08_RS17515	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LLJ08_RS17530	COG1176	ABC-type spermidine putrescine transport system, permease component I
LLJ08_RS17540	COG3842	ATPase activity
LLJ08_RS17545	COG2197	response regulator
LLJ08_RS17560	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LLJ08_RS17565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LLJ08_RS17575	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LLJ08_RS17580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LLJ08_RS17585	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LLJ08_RS17590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LLJ08_RS17595	COG2967	ApaG domain
LLJ08_RS17600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LLJ08_RS17605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLJ08_RS17610	COG2766	serine protein kinase
LLJ08_RS17615	COG2718	Belongs to the UPF0229 family
LLJ08_RS17620	COG2719	SpoVR family
LLJ08_RS17640	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LLJ08_RS17645	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LLJ08_RS17650	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LLJ08_RS17655	COG0358	DNA primase activity
LLJ08_RS17660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LLJ08_RS17670	COG0471	metal ion transport
LLJ08_RS17670	COG3273	potassium ion transport
LLJ08_RS17675	COG2873	o-acetylhomoserine
LLJ08_RS17680	COG3118	belongs to the thioredoxin family
LLJ08_RS17695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLJ08_RS17700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLJ08_RS17715	COG0463	Glycosyl transferase, family 2
LLJ08_RS17725	COG2986	histidine ammonia-lyase
LLJ08_RS17745	COG0644	oxidoreductase
LLJ08_RS17765	COG1028	Short-chain dehydrogenase reductase Sdr
LLJ08_RS17770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LLJ08_RS17785	COG0583	DNA-binding transcription factor activity
LLJ08_RS17790	COG2814	Major facilitator Superfamily
LLJ08_RS17800	COG0493	'glutamate synthase
LLJ08_RS17805	COG0067	glutamate synthase
LLJ08_RS17805	COG0069	glutamate synthase activity
LLJ08_RS17805	COG0070	glutamate synthase
LLJ08_RS17815	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LLJ08_RS17820	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LLJ08_RS17855	COG0281	malic enzyme
LLJ08_RS17865	COG0254	rRNA binding
LLJ08_RS17870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LLJ08_RS17875	COG0018	arginyl-trna synthetase
LLJ08_RS17890	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LLJ08_RS17905	COG0248	Ppx GppA phosphatase
LLJ08_RS17910	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LLJ08_RS17920	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LLJ08_RS17935	COG1671	Belongs to the UPF0178 family
LLJ08_RS17940	COG1280	lysine exporter protein (LysE YggA)
LLJ08_RS17945	COG0861	Integral membrane protein TerC family
LLJ08_RS17955	COG0488	(ABC) transporter
LLJ08_RS17975	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LLJ08_RS18005	COG3275	phosphorelay sensor kinase activity
LLJ08_RS18010	COG0165	Argininosuccinate lyase
LLJ08_RS18015	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LLJ08_RS18050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LLJ08_RS18055	COG1965	Belongs to the frataxin family
LLJ08_RS18070	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LLJ08_RS18080	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LLJ08_RS18095	COG0432	Pfam Uncharacterised protein family UPF0047
LLJ08_RS18100	COG0004	ammonium transporteR
LLJ08_RS18105	COG0004	ammonium transporteR
LLJ08_RS18110	COG0347	Belongs to the P(II) protein family
LLJ08_RS18120	COG0606	chelatase, subunit chli
LLJ08_RS18125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LLJ08_RS18135	COG0210	DNA helicase
LLJ08_RS18140	COG1272	protein, Hemolysin III
LLJ08_RS18145	COG1414	Transcriptional regulator
LLJ08_RS18155	COG1454	alcohol dehydrogenase
LLJ08_RS18165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LLJ08_RS18170	COG0366	Alpha amylase catalytic
LLJ08_RS18185	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LLJ08_RS18210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LLJ08_RS18220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LLJ08_RS18225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LLJ08_RS18240	COG0840	transmembrane signaling receptor activity
LLJ08_RS18245	COG1250	3-hydroxyacyl-CoA dehydrogenase
LLJ08_RS18260	COG2003	Belongs to the UPF0758 family
LLJ08_RS18265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LLJ08_RS18270	COG0756	dUTP diphosphatase activity
LLJ08_RS18280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LLJ08_RS18295	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LLJ08_RS18300	COG0708	Exodeoxyribonuclease III
LLJ08_RS18310	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LLJ08_RS18315	COG1561	YicC-like family, N-terminal region
LLJ08_RS18325	COG1758	RNA polymerase activity
LLJ08_RS18330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LLJ08_RS18355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LLJ08_RS18375	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LLJ08_RS18380	COG1704	LemA family
LLJ08_RS18385	COG0583	DNA-binding transcription factor activity
LLJ08_RS18400	COG1960	acyl-CoA dehydrogenase activity
LLJ08_RS18405	COG0583	DNA-binding transcription factor activity
LLJ08_RS18430	COG1620	l-lactate permease
LLJ08_RS18435	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LLJ08_RS18440	COG3193	protein, possibly involved in utilization of glycolate and propanediol
LLJ08_RS18445	COG0247	lactate metabolic process
LLJ08_RS18450	COG0277	FAD linked oxidase domain protein
LLJ08_RS18455	COG0277	FAD linked oxidase domain protein
LLJ08_RS18460	COG2186	Transcriptional regulator
LLJ08_RS18470	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LLJ08_RS18485	COG1253	flavin adenine dinucleotide binding
LLJ08_RS18495	COG0739	heme binding
LLJ08_RS18515	COG0411	ABC transporter
LLJ08_RS18525	COG0559	Belongs to the binding-protein-dependent transport system permease family
LLJ08_RS18535	COG1192	Involved in chromosome partitioning
LLJ08_RS18540	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LLJ08_RS18545	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LLJ08_RS18550	COG0730	response to heat
LLJ08_RS18565	COG0494	nUDIX hydrolase
LLJ08_RS18580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LLJ08_RS18585	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LLJ08_RS18605	COG0179	Fumarylacetoacetate (FAA) hydrolase
LLJ08_RS18610	COG0277	FAD linked oxidase domain protein
LLJ08_RS18615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LLJ08_RS18640	COG2197	response regulator
LLJ08_RS18665	COG0651	ATP synthesis coupled electron transport
LLJ08_RS18670	COG0651	ATP synthesis coupled electron transport
LLJ08_RS18690	COG1320	monovalent cation:proton antiporter activity
LLJ08_RS18715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LLJ08_RS18720	COG5001	Diguanylate cyclase
LLJ08_RS18740	COG4807	Protein conserved in bacteria
LLJ08_RS18745	COG2204	response regulator
LLJ08_RS18780	COG2203	Gaf domain
LLJ08_RS18780	COG3706	GGDEF domain
LLJ08_RS18780	COG4251	negative regulation of phosphorylation
LLJ08_RS18780	COG5001	Diguanylate cyclase
LLJ08_RS18790	COG2207	Transcriptional regulator
LLJ08_RS18805	COG2819	hydrolase of the alpha beta superfamily
LLJ08_RS18820	COG4565	transcriptional regulatory protein
LLJ08_RS18825	COG3290	protein histidine kinase activity
LLJ08_RS18830	COG3493	citrate carrier protein
LLJ08_RS18840	COG1217	gtp-binding protein TYPA
LLJ08_RS18845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLJ08_RS18845	COG0301	tRNA thio-modification
LLJ08_RS18865	COG3852	Histidine kinase
LLJ08_RS18885	COG0243	molybdopterin cofactor binding
LLJ08_RS18895	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LLJ08_RS18905	COG0840	transmembrane signaling receptor activity
LLJ08_RS18915	COG2226	methyltransferase
LLJ08_RS18925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LLJ08_RS18930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LLJ08_RS18935	COG0140	phosphoribosyl-ATP diphosphatase activity
LLJ08_RS18940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LLJ08_RS18945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LLJ08_RS18965	COG1490	D-aminoacyl-tRNA deacylase activity
LLJ08_RS18995	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LLJ08_RS19000	COG0058	SHG alpha-glucan phosphorylase activity
LLJ08_RS19015	COG1218	3'(2'),5'-bisphosphate nucleotidase
LLJ08_RS19020	COG0494	nUDIX hydrolase
LLJ08_RS19025	COG1011	Hydrolase
LLJ08_RS19030	COG4191	Histidine kinase
LLJ08_RS19030	COG0784	Response regulator, receiver
LLJ08_RS19050	COG1454	alcohol dehydrogenase
LLJ08_RS19055	COG1960	acyl-CoA dehydrogenase activity
LLJ08_RS19060	COG1024	Enoyl-CoA hydratase
LLJ08_RS19060	COG1250	3-hydroxyacyl-CoA dehydrogenase
LLJ08_RS19070	COG1366	Belongs to the anti-sigma-factor antagonist family
LLJ08_RS19075	COG1366	Belongs to the anti-sigma-factor antagonist family
LLJ08_RS19080	COG2172	sigma factor antagonist activity
LLJ08_RS19090	COG2205	protein histidine kinase activity
LLJ08_RS19095	COG0784	Response regulator, receiver
LLJ08_RS19095	COG4191	Histidine kinase
LLJ08_RS19100	COG1278	Cold shock
LLJ08_RS19125	COG0667	Aldo Keto reductase
LLJ08_RS19135	COG0840	transmembrane signaling receptor activity
LLJ08_RS19140	COG0840	transmembrane signaling receptor activity
LLJ08_RS19145	COG0514	ATP-dependent DNA helicase (RecQ)
LLJ08_RS19150	COG0778	Nitroreductase
LLJ08_RS19160	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LLJ08_RS19165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LLJ08_RS19170	COG0189	ligase activity
LLJ08_RS19170	COG4067	protein conserved in archaea
LLJ08_RS19175	COG0189	ligase activity
LLJ08_RS19190	COG2183	response to ionizing radiation
LLJ08_RS19200	COG2918	glutathione biosynthetic process
LLJ08_RS19215	COG0306	phosphate transporter
LLJ08_RS19220	COG1392	Phosphate transport regulator
LLJ08_RS19230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LLJ08_RS19240	COG2989	Protein conserved in bacteria
LLJ08_RS19255	COG1764	response to oxidative stress
LLJ08_RS19260	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LLJ08_RS19270	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LLJ08_RS19290	COG0583	DNA-binding transcription factor activity
LLJ08_RS19310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LLJ08_RS19320	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LLJ08_RS19340	COG2258	MOSC domain
LLJ08_RS19345	COG0436	Aminotransferase
LLJ08_RS19350	COG0450	alkyl hydroperoxide reductase
LLJ08_RS19360	COG5583	Uncharacterized small protein (DUF2292)
LLJ08_RS19365	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LLJ08_RS19375	COG4208	sulfate ABC transporter
LLJ08_RS19385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LLJ08_RS19415	COG2205	protein histidine kinase activity
LLJ08_RS19420	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LLJ08_RS19420	COG1082	Xylose isomerase domain protein TIM barrel
LLJ08_RS19430	COG0583	DNA-binding transcription factor activity
LLJ08_RS19440	COG1301	dicarboxylic acid transport
LLJ08_RS19465	COG1115	amino acid carrier protein
LLJ08_RS19470	COG0252	asparaginase activity
LLJ08_RS19485	COG2066	Belongs to the glutaminase family
LLJ08_RS19500	COG5016	pyruvate
LLJ08_RS19500	COG0511	ligase activity, forming carbon-carbon bonds
LLJ08_RS19505	COG0439	Biotin carboxylase
LLJ08_RS19510	COG0583	DNA-binding transcription factor activity
LLJ08_RS19520	COG0837	glucose binding
LLJ08_RS19520	COG1737	Transcriptional regulator
LLJ08_RS19525	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LLJ08_RS19535	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LLJ08_RS19540	COG1917	Cupin 2, conserved barrel domain protein
LLJ08_RS19545	COG5285	phytanoyl-CoA dioxygenase
LLJ08_RS19550	COG0527	aspartate kinase activity
LLJ08_RS19555	COG2841	Protein conserved in bacteria
LLJ08_RS19560	COG0826	peptidase U32
LLJ08_RS19570	COG0210	DNA helicase
LLJ08_RS19575	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LLJ08_RS19590	COG1764	response to oxidative stress
LLJ08_RS19605	COG0437	4 iron, 4 sulfur cluster binding
LLJ08_RS19610	COG2864	formate dehydrogenase
LLJ08_RS19615	COG3058	Necessary for formate dehydrogenase activity
LLJ08_RS19620	COG1921	L-seryl-tRNASec selenium transferase activity
LLJ08_RS19625	COG3276	selenocysteine insertion sequence binding
LLJ08_RS19690	COG0509	glycine decarboxylation via glycine cleavage system
LLJ08_RS19700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LLJ08_RS19705	COG0589	response to stress
LLJ08_RS19710	COG0659	secondary active sulfate transmembrane transporter activity
LLJ08_RS19725	COG2204	response regulator
LLJ08_RS19730	COG4941	Belongs to the sigma-70 factor family
LLJ08_RS19735	COG3795	YCII-related domain
LLJ08_RS19760	COG4191	Histidine kinase
LLJ08_RS19760	COG0784	Response regulator, receiver
LLJ08_RS19765	COG1960	acyl-CoA dehydrogenase activity
LLJ08_RS19770	COG2706	6-phosphogluconolactonase activity
LLJ08_RS19785	COG4786	Flagellar basal body rod
LLJ08_RS19785	COG1256	bacterial-type flagellum assembly
LLJ08_RS19790	COG0741	lytic transglycosylase activity
LLJ08_RS19795	COG1706	bacterial-type flagellum-dependent cell motility
LLJ08_RS19800	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LLJ08_RS19805	COG4786	Flagellar basal body rod
LLJ08_RS19810	COG4787	bacterial-type flagellum-dependent cell motility
LLJ08_RS19820	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LLJ08_RS19825	COG1558	bacterial-type flagellum-dependent cell motility
LLJ08_RS19830	COG1815	bacterial-type flagellum-dependent cell motility
LLJ08_RS19840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LLJ08_RS19860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LLJ08_RS19865	COG1191	sigma factor activity
LLJ08_RS19890	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LLJ08_RS19920	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LLJ08_RS19930	COG1677	Flagellar hook-basal body complex protein FliE
LLJ08_RS19965	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LLJ08_RS20015	COG0583	DNA-binding transcription factor activity
LLJ08_RS20020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LLJ08_RS20095	COG2249	NAD(P)H dehydrogenase (quinone) activity
LLJ08_RS20105	COG2207	Transcriptional regulator
LLJ08_RS20175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LLJ08_RS20185	COG4589	Belongs to the CDS family
LLJ08_RS20190	COG1611	Belongs to the LOG family
LLJ08_RS20205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLJ08_RS20210	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LLJ08_RS20215	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LLJ08_RS20220	COG0318	PFAM AMP-dependent synthetase and ligase
LLJ08_RS20240	COG2814	Major facilitator Superfamily
LLJ08_RS20265	COG1960	acyl-CoA dehydrogenase activity
LLJ08_RS20270	COG1024	Enoyl-CoA hydratase
LLJ08_RS20270	COG1250	3-hydroxyacyl-CoA dehydrogenase
LLJ08_RS20285	COG3909	cytochrome
LLJ08_RS20290	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
LLJ08_RS20345	COG3179	chitinase
LLJ08_RS20360	COG2010	Cytochrome c
LLJ08_RS20365	COG0753	catalase activity
LLJ08_RS20370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LLJ08_RS20375	COG1127	ABC transporter
LLJ08_RS20390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LLJ08_RS20395	COG1129	ABC transporter
LLJ08_RS20395	COG0842	Transport permease protein
LLJ08_RS20400	COG0842	Transport permease protein
LLJ08_RS20470	COG4771	TonB-dependent receptor
LLJ08_RS20485	COG1116	anion transmembrane transporter activity
LLJ08_RS20495	COG1177	transmembrane transport
LLJ08_RS20500	COG1176	ABC-type spermidine putrescine transport system, permease component I
LLJ08_RS20505	COG3842	ATPase activity
LLJ08_RS20525	COG0174	glutamine synthetase
LLJ08_RS20530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LLJ08_RS20535	COG0174	glutamine synthetase
LLJ08_RS20550	COG2957	Belongs to the agmatine deiminase family
LLJ08_RS20570	COG3706	GGDEF domain
LLJ08_RS20580	COG4191	Histidine kinase
LLJ08_RS20585	COG0745	RESPONSE REGULATOR receiver
LLJ08_RS20590	COG5002	protein histidine kinase activity
LLJ08_RS20595	COG0745	RESPONSE REGULATOR receiver
LLJ08_RS20605	COG0784	Response regulator, receiver
LLJ08_RS20605	COG5002	protein histidine kinase activity
LLJ08_RS20605	COG2205	protein histidine kinase activity
LLJ08_RS20610	COG0745	RESPONSE REGULATOR receiver
LLJ08_RS20630	COG1012	belongs to the aldehyde dehydrogenase family
LLJ08_RS20635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LLJ08_RS20645	COG0735	belongs to the Fur family
LLJ08_RS20650	COG1121	(ABC) transporter
LLJ08_RS20655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LLJ08_RS20660	COG1451	nucleotide metabolic process
LLJ08_RS20665	COG0471	metal ion transport
LLJ08_RS20680	COG2011	ABC-type metal ion transport system permease component
LLJ08_RS20700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LLJ08_RS20705	COG0339	signal peptide processing
LLJ08_RS20735	COG0659	secondary active sulfate transmembrane transporter activity
LLJ08_RS20745	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LLJ08_RS20750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LLJ08_RS20755	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LLJ08_RS20785	COG0109	protoheme IX farnesyltransferase activity
LLJ08_RS20810	COG1595	DNA-templated transcription, initiation
LLJ08_RS20825	COG0523	cobalamin synthesis protein
LLJ08_RS20840	COG4251	negative regulation of phosphorylation
LLJ08_RS20845	COG0784	Response regulator, receiver
LLJ08_RS20850	COG4191	Histidine kinase
LLJ08_RS20850	COG0784	Response regulator, receiver
LLJ08_RS20860	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LLJ08_RS20865	COG1349	DNA-binding transcription factor activity
LLJ08_RS20870	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LLJ08_RS20875	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LLJ08_RS20880	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LLJ08_RS20885	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LLJ08_RS20890	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LLJ08_RS20895	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LLJ08_RS20900	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LLJ08_RS20910	COG0356	it plays a direct role in the translocation of protons across the membrane
LLJ08_RS20915	COG3312	ion transport
LLJ08_RS20920	COG1475	DNA binding
LLJ08_RS20925	COG1192	Involved in chromosome partitioning
LLJ08_RS20930	COG0357	Ribosomal RNA small subunit methyltransferase G
LLJ08_RS20935	COG0445	tRNA wobble uridine modification
LLJ08_RS20940	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LLJ08_RS20945	COG0706	membrane insertase activity
LLJ08_RS20950	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LLJ08_RS20955	COG0594	ribonuclease P activity
LLJ08_RS20960	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LLJ08_RS20995	COG2814	Major facilitator Superfamily
LLJ08_RS21000	COG2814	Major facilitator Superfamily