locus-tag	class	description
OSV15_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OSV15_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OSV15_RS00025	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OSV15_RS00040	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OSV15_RS00180	COG3706	GGDEF domain
OSV15_RS00195	COG0751	glycine-tRNA ligase activity
OSV15_RS00205	COG2818	Glycosylase
OSV15_RS00225	COG1126	abc transporter atp-binding protein
OSV15_RS00230	COG0765	amino acid transport
OSV15_RS00235	COG0765	amino acid transport
OSV15_RS00240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OSV15_RS00245	COG0569	domain protein
OSV15_RS00250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OSV15_RS00255	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OSV15_RS00260	COG0242	peptide deformylase activity
OSV15_RS00265	COG1652	LysM domain
OSV15_RS00270	COG0758	DNA mediated transformation
OSV15_RS00275	COG0009	L-threonylcarbamoyladenylate synthase
OSV15_RS00285	COG0408	coproporphyrinogen oxidase activity
OSV15_RS00290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OSV15_RS00305	COG1686	Belongs to the peptidase S11 family
OSV15_RS00330	COG2011	ABC-type metal ion transport system permease component
OSV15_RS00345	COG1451	nucleotide metabolic process
OSV15_RS00350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OSV15_RS00355	COG1121	(ABC) transporter
OSV15_RS00360	COG0735	belongs to the Fur family
OSV15_RS00370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OSV15_RS00375	COG1012	belongs to the aldehyde dehydrogenase family
OSV15_RS00395	COG0745	RESPONSE REGULATOR receiver
OSV15_RS00400	COG5002	protein histidine kinase activity
OSV15_RS00410	COG0745	RESPONSE REGULATOR receiver
OSV15_RS00415	COG5002	protein histidine kinase activity
OSV15_RS00420	COG0745	RESPONSE REGULATOR receiver
OSV15_RS00425	COG4191	Histidine kinase
OSV15_RS00435	COG3706	GGDEF domain
OSV15_RS00445	COG2957	Belongs to the agmatine deiminase family
OSV15_RS00460	COG0174	glutamine synthetase
OSV15_RS00465	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OSV15_RS00470	COG0174	glutamine synthetase
OSV15_RS00490	COG3842	ATPase activity
OSV15_RS00495	COG1176	ABC-type spermidine putrescine transport system, permease component I
OSV15_RS00500	COG1177	transmembrane transport
OSV15_RS00575	COG0842	Transport permease protein
OSV15_RS00580	COG1129	ABC transporter
OSV15_RS00580	COG0842	Transport permease protein
OSV15_RS00585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OSV15_RS00600	COG1127	ABC transporter
OSV15_RS00605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OSV15_RS00610	COG0753	catalase activity
OSV15_RS00615	COG2010	Cytochrome c
OSV15_RS00680	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
OSV15_RS00685	COG3909	cytochrome
OSV15_RS00700	COG1250	3-hydroxyacyl-CoA dehydrogenase
OSV15_RS00700	COG1024	Enoyl-CoA hydratase
OSV15_RS00705	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS00710	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS00730	COG2814	Major facilitator Superfamily
OSV15_RS00750	COG0318	PFAM AMP-dependent synthetase and ligase
OSV15_RS00755	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OSV15_RS00760	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OSV15_RS00775	COG1611	Belongs to the LOG family
OSV15_RS00780	COG4589	Belongs to the CDS family
OSV15_RS00790	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OSV15_RS00860	COG2207	Transcriptional regulator
OSV15_RS00870	COG2249	NAD(P)H dehydrogenase (quinone) activity
OSV15_RS00940	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OSV15_RS00945	COG0583	DNA-binding transcription factor activity
OSV15_RS00995	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OSV15_RS01030	COG1677	Flagellar hook-basal body complex protein FliE
OSV15_RS01040	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OSV15_RS01070	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OSV15_RS01095	COG1191	sigma factor activity
OSV15_RS01100	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OSV15_RS01120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OSV15_RS01135	COG1558	bacterial-type flagellum-dependent cell motility
OSV15_RS01140	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OSV15_RS01150	COG4787	bacterial-type flagellum-dependent cell motility
OSV15_RS01155	COG4786	Flagellar basal body rod
OSV15_RS01165	COG1706	bacterial-type flagellum-dependent cell motility
OSV15_RS01170	COG0741	lytic transglycosylase activity
OSV15_RS01175	COG1256	bacterial-type flagellum assembly
OSV15_RS01175	COG4786	Flagellar basal body rod
OSV15_RS01190	COG2706	6-phosphogluconolactonase activity
OSV15_RS01195	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS01200	COG4191	Histidine kinase
OSV15_RS01200	COG0784	Response regulator, receiver
OSV15_RS01225	COG3795	YCII-related domain
OSV15_RS01230	COG4941	Belongs to the sigma-70 factor family
OSV15_RS01235	COG2204	response regulator
OSV15_RS01240	COG4191	Histidine kinase
OSV15_RS01250	COG0659	secondary active sulfate transmembrane transporter activity
OSV15_RS01255	COG0589	response to stress
OSV15_RS01260	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OSV15_RS01270	COG0509	glycine decarboxylation via glycine cleavage system
OSV15_RS01280	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS01290	COG3276	selenocysteine insertion sequence binding
OSV15_RS01295	COG1921	L-seryl-tRNASec selenium transferase activity
OSV15_RS01300	COG3058	Necessary for formate dehydrogenase activity
OSV15_RS01305	COG2864	formate dehydrogenase
OSV15_RS01310	COG0437	4 iron, 4 sulfur cluster binding
OSV15_RS01325	COG1764	response to oxidative stress
OSV15_RS01340	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OSV15_RS01345	COG0210	DNA helicase
OSV15_RS01355	COG0826	peptidase U32
OSV15_RS01360	COG2841	Protein conserved in bacteria
OSV15_RS01365	COG0527	aspartate kinase activity
OSV15_RS01370	COG5285	phytanoyl-CoA dioxygenase
OSV15_RS01375	COG1917	Cupin 2, conserved barrel domain protein
OSV15_RS01380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OSV15_RS01390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OSV15_RS01395	COG0837	glucose binding
OSV15_RS01395	COG1737	Transcriptional regulator
OSV15_RS01405	COG0583	DNA-binding transcription factor activity
OSV15_RS01410	COG0439	Biotin carboxylase
OSV15_RS01415	COG5016	pyruvate
OSV15_RS01415	COG0511	ligase activity, forming carbon-carbon bonds
OSV15_RS01430	COG2066	Belongs to the glutaminase family
OSV15_RS01445	COG0252	asparaginase activity
OSV15_RS01450	COG1115	amino acid carrier protein
OSV15_RS01460	COG1301	dicarboxylic acid transport
OSV15_RS01470	COG0583	DNA-binding transcription factor activity
OSV15_RS01480	COG1082	Xylose isomerase domain protein TIM barrel
OSV15_RS01480	COG3185	4-Hydroxyphenylpyruvate dioxygenase
OSV15_RS01485	COG2205	protein histidine kinase activity
OSV15_RS01515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OSV15_RS01525	COG4208	sulfate ABC transporter
OSV15_RS01535	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OSV15_RS01540	COG5583	Uncharacterized small protein (DUF2292)
OSV15_RS01550	COG0450	alkyl hydroperoxide reductase
OSV15_RS01570	COG0583	DNA-binding transcription factor activity
OSV15_RS01575	COG2814	Major facilitator Superfamily
OSV15_RS01600	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OSV15_RS01605	COG1764	response to oxidative stress
OSV15_RS01620	COG2989	Protein conserved in bacteria
OSV15_RS01630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OSV15_RS01640	COG1392	Phosphate transport regulator
OSV15_RS01645	COG0306	phosphate transporter
OSV15_RS01660	COG2918	glutathione biosynthetic process
OSV15_RS01670	COG2183	response to ionizing radiation
OSV15_RS01675	COG3118	belongs to the thioredoxin family
OSV15_RS01675	COG0457	Tetratricopeptide repeat
OSV15_RS01680	COG1215	transferase activity, transferring glycosyl groups
OSV15_RS01685	COG1215	transferase activity, transferring glycosyl groups
OSV15_RS01690	COG1192	Involved in chromosome partitioning
OSV15_RS01700	COG2194	sulfuric ester hydrolase activity
OSV15_RS01730	COG0189	ligase activity
OSV15_RS01735	COG0189	ligase activity
OSV15_RS01735	COG4067	protein conserved in archaea
OSV15_RS01740	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OSV15_RS01750	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OSV15_RS01760	COG0778	Nitroreductase
OSV15_RS01765	COG0514	ATP-dependent DNA helicase (RecQ)
OSV15_RS01770	COG0840	transmembrane signaling receptor activity
OSV15_RS01785	COG0019	diaminopimelate decarboxylase activity
OSV15_RS01800	COG0747	negative chemotaxis
OSV15_RS01810	COG0667	Aldo Keto reductase
OSV15_RS01835	COG0784	Response regulator, receiver
OSV15_RS01835	COG4191	Histidine kinase
OSV15_RS01840	COG2205	protein histidine kinase activity
OSV15_RS01850	COG2172	sigma factor antagonist activity
OSV15_RS01855	COG1366	Belongs to the anti-sigma-factor antagonist family
OSV15_RS01860	COG1366	Belongs to the anti-sigma-factor antagonist family
OSV15_RS01870	COG1024	Enoyl-CoA hydratase
OSV15_RS01870	COG1250	3-hydroxyacyl-CoA dehydrogenase
OSV15_RS01875	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS01880	COG1454	alcohol dehydrogenase
OSV15_RS01895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OSV15_RS01905	COG1011	Hydrolase
OSV15_RS01910	COG0494	nUDIX hydrolase
OSV15_RS01915	COG1218	3'(2'),5'-bisphosphate nucleotidase
OSV15_RS01930	COG0058	SHG alpha-glucan phosphorylase activity
OSV15_RS01935	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
OSV15_RS01965	COG1490	D-aminoacyl-tRNA deacylase activity
OSV15_RS01985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OSV15_RS01990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OSV15_RS01995	COG0140	phosphoribosyl-ATP diphosphatase activity
OSV15_RS02000	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OSV15_RS02005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OSV15_RS02015	COG2226	methyltransferase
OSV15_RS02035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OSV15_RS02040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OSV15_RS02040	COG2010	Cytochrome c
OSV15_RS02055	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OSV15_RS02085	COG3852	Histidine kinase
OSV15_RS02105	COG0301	tRNA thio-modification
OSV15_RS02105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OSV15_RS02110	COG1217	gtp-binding protein TYPA
OSV15_RS02155	COG2204	response regulator
OSV15_RS02160	COG4807	Protein conserved in bacteria
OSV15_RS02165	COG5001	Diguanylate cyclase
OSV15_RS02170	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OSV15_RS02195	COG1320	monovalent cation:proton antiporter activity
OSV15_RS02215	COG0651	ATP synthesis coupled electron transport
OSV15_RS02220	COG0651	ATP synthesis coupled electron transport
OSV15_RS02265	COG2197	response regulator
OSV15_RS02290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OSV15_RS02295	COG0277	FAD linked oxidase domain protein
OSV15_RS02300	COG0179	Fumarylacetoacetate (FAA) hydrolase
OSV15_RS02305	COG3204	pilus organization
OSV15_RS02320	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OSV15_RS02325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OSV15_RS02340	COG0494	nUDIX hydrolase
OSV15_RS02355	COG0730	response to heat
OSV15_RS02360	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OSV15_RS02365	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OSV15_RS02370	COG1192	Involved in chromosome partitioning
OSV15_RS02380	COG0559	Belongs to the binding-protein-dependent transport system permease family
OSV15_RS02390	COG0411	ABC transporter
OSV15_RS02410	COG0739	heme binding
OSV15_RS02415	COG1253	flavin adenine dinucleotide binding
OSV15_RS02430	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OSV15_RS02440	COG2186	Transcriptional regulator
OSV15_RS02445	COG0277	FAD linked oxidase domain protein
OSV15_RS02450	COG0277	FAD linked oxidase domain protein
OSV15_RS02455	COG0247	lactate metabolic process
OSV15_RS02460	COG3193	protein, possibly involved in utilization of glycolate and propanediol
OSV15_RS02465	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OSV15_RS02470	COG1620	l-lactate permease
OSV15_RS02495	COG0583	DNA-binding transcription factor activity
OSV15_RS02500	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS02515	COG0583	DNA-binding transcription factor activity
OSV15_RS02520	COG1704	LemA family
OSV15_RS02525	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OSV15_RS02545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OSV15_RS02575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OSV15_RS02580	COG1758	RNA polymerase activity
OSV15_RS02590	COG1561	YicC-like family, N-terminal region
OSV15_RS02595	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OSV15_RS02605	COG0708	Exodeoxyribonuclease III
OSV15_RS02610	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OSV15_RS02625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OSV15_RS02635	COG0756	dUTP diphosphatase activity
OSV15_RS02640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OSV15_RS02645	COG2003	Belongs to the UPF0758 family
OSV15_RS02660	COG1250	3-hydroxyacyl-CoA dehydrogenase
OSV15_RS02665	COG0840	transmembrane signaling receptor activity
OSV15_RS02680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OSV15_RS02685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OSV15_RS02695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OSV15_RS02700	COG0251	oxidation-reduction process
OSV15_RS02720	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OSV15_RS02730	COG0366	Alpha amylase catalytic
OSV15_RS02735	COG0366	Alpha amylase catalytic
OSV15_RS02740	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OSV15_RS02750	COG1454	alcohol dehydrogenase
OSV15_RS02760	COG1414	Transcriptional regulator
OSV15_RS02765	COG1272	protein, Hemolysin III
OSV15_RS02770	COG0210	DNA helicase
OSV15_RS02780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OSV15_RS02785	COG0606	chelatase, subunit chli
OSV15_RS02795	COG0347	Belongs to the P(II) protein family
OSV15_RS02800	COG0004	ammonium transporteR
OSV15_RS02805	COG0004	ammonium transporteR
OSV15_RS02810	COG0432	Pfam Uncharacterised protein family UPF0047
OSV15_RS02825	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OSV15_RS02835	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OSV15_RS02850	COG1965	Belongs to the frataxin family
OSV15_RS02855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OSV15_RS02860	COG3072	Adenylate cyclase
OSV15_RS02890	COG0165	Argininosuccinate lyase
OSV15_RS02895	COG3275	phosphorelay sensor kinase activity
OSV15_RS02905	COG0181	hydroxymethylbilane synthase activity
OSV15_RS02925	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OSV15_RS02945	COG0488	(ABC) transporter
OSV15_RS02955	COG0861	Integral membrane protein TerC family
OSV15_RS02960	COG1280	lysine exporter protein (LysE YggA)
OSV15_RS02965	COG1671	Belongs to the UPF0178 family
OSV15_RS02980	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
OSV15_RS02990	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OSV15_RS02995	COG0248	Ppx GppA phosphatase
OSV15_RS03010	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OSV15_RS03025	COG0018	arginyl-trna synthetase
OSV15_RS03030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OSV15_RS03035	COG0254	rRNA binding
OSV15_RS03045	COG0281	malic enzyme
OSV15_RS03080	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OSV15_RS03085	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OSV15_RS03095	COG0069	glutamate synthase activity
OSV15_RS03095	COG0067	glutamate synthase
OSV15_RS03095	COG0070	glutamate synthase
OSV15_RS03100	COG0493	'glutamate synthase
OSV15_RS03110	COG2814	Major facilitator Superfamily
OSV15_RS03120	COG0583	DNA-binding transcription factor activity
OSV15_RS03135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OSV15_RS03140	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS03180	COG2986	histidine ammonia-lyase
OSV15_RS03190	COG0463	Glycosyl transferase, family 2
OSV15_RS03205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OSV15_RS03210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OSV15_RS03225	COG3118	belongs to the thioredoxin family
OSV15_RS03230	COG2873	o-acetylhomoserine
OSV15_RS03235	COG3273	potassium ion transport
OSV15_RS03235	COG0471	metal ion transport
OSV15_RS03370	COG4695	Portal protein
OSV15_RS03460	COG4974	Belongs to the 'phage' integrase family
OSV15_RS03475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OSV15_RS03480	COG0358	DNA primase activity
OSV15_RS03485	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OSV15_RS03490	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OSV15_RS03495	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OSV15_RS03510	COG0617	tRNA 3'-terminal CCA addition
OSV15_RS03515	COG2719	SpoVR family
OSV15_RS03520	COG2718	Belongs to the UPF0229 family
OSV15_RS03525	COG2766	serine protein kinase
OSV15_RS03530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OSV15_RS03535	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OSV15_RS03540	COG2967	ApaG domain
OSV15_RS03545	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OSV15_RS03550	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OSV15_RS03555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OSV15_RS03560	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OSV15_RS03570	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OSV15_RS03590	COG2197	response regulator
OSV15_RS03595	COG3842	ATPase activity
OSV15_RS03605	COG1176	ABC-type spermidine putrescine transport system, permease component I
OSV15_RS03610	COG1177	transmembrane transport
OSV15_RS03620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OSV15_RS03625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OSV15_RS03645	COG0512	Glutamine amidotransferase of anthranilate synthase
OSV15_RS03650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OSV15_RS03655	COG0134	indole-3-glycerol-phosphate synthase activity
OSV15_RS03665	COG1765	OsmC-like protein
OSV15_RS03670	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
OSV15_RS03675	COG0537	adenosine 5'-monophosphoramidase activity
OSV15_RS03680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OSV15_RS03690	COG1981	membrane
OSV15_RS03695	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OSV15_RS03700	COG0316	Belongs to the HesB IscA family
OSV15_RS03705	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OSV15_RS03710	COG0739	heme binding
OSV15_RS03715	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OSV15_RS03745	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OSV15_RS03745	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OSV15_RS03750	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OSV15_RS03775	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OSV15_RS03795	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OSV15_RS03800	COG0081	regulation of translation
OSV15_RS03805	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OSV15_RS03810	COG0222	ribosome binding
OSV15_RS03815	COG0085	RNA polymerase activity
OSV15_RS03820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OSV15_RS03825	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OSV15_RS03830	COG0049	tRNA binding
OSV15_RS03835	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OSV15_RS03840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OSV15_RS03845	COG0051	transcription antitermination factor activity, RNA binding
OSV15_RS03850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OSV15_RS03855	COG0088	Forms part of the polypeptide exit tunnel
OSV15_RS03860	COG0089	rRNA binding
OSV15_RS03865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OSV15_RS03870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OSV15_RS03875	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OSV15_RS03880	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OSV15_RS03885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OSV15_RS03890	COG0255	Belongs to the universal ribosomal protein uL29 family
OSV15_RS03895	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OSV15_RS03900	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OSV15_RS03905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OSV15_RS03910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OSV15_RS03915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OSV15_RS03920	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OSV15_RS03925	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OSV15_RS03930	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OSV15_RS03935	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OSV15_RS03945	COG0200	Binds to the 23S rRNA
OSV15_RS03955	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OSV15_RS03960	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OSV15_RS03965	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OSV15_RS03970	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OSV15_RS03975	COG0202	RNA polymerase activity
OSV15_RS03980	COG0203	ribosomal protein L17
OSV15_RS03995	COG2814	Major facilitator Superfamily
OSV15_RS04010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OSV15_RS04015	COG3047	cAMP biosynthetic process
OSV15_RS04025	COG0811	peptide transport
OSV15_RS04030	COG0811	peptide transport
OSV15_RS04035	COG0848	biopolymer transport protein
OSV15_RS04060	COG4181	ATPase activity
OSV15_RS04075	COG3118	belongs to the thioredoxin family
OSV15_RS04080	COG2391	methyltransferase activity
OSV15_RS04085	COG0425	Belongs to the sulfur carrier protein TusA family
OSV15_RS04095	COG2264	protein methyltransferase activity
OSV15_RS04110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OSV15_RS04110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OSV15_RS04125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OSV15_RS04130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OSV15_RS04140	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OSV15_RS04145	COG3577	Aspartyl protease
OSV15_RS04150	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OSV15_RS04160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OSV15_RS04175	COG0420	3'-5' exonuclease activity
OSV15_RS04200	COG3212	peptidase
OSV15_RS04235	COG1040	competence protein
OSV15_RS04240	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OSV15_RS04245	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS04250	COG2610	gluconate transmembrane transporter activity
OSV15_RS04255	COG2031	fatty acid transporter
OSV15_RS04270	COG1522	sequence-specific DNA binding
OSV15_RS04285	COG0733	neurotransmitter:sodium symporter activity
OSV15_RS04295	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OSV15_RS04305	COG0625	glutathione transferase activity
OSV15_RS04310	COG0733	neurotransmitter:sodium symporter activity
OSV15_RS04330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OSV15_RS04330	COG4651	solute:proton antiporter activity
OSV15_RS04335	COG0513	Belongs to the DEAD box helicase family
OSV15_RS04360	COG0123	including yeast histone deacetylase and acetoin utilization protein
OSV15_RS04370	COG1946	Acyl-CoA thioesterase
OSV15_RS04380	COG2321	neutral zinc metallopeptidase
OSV15_RS04405	COG2197	response regulator
OSV15_RS04410	COG3850	Histidine kinase
OSV15_RS04425	COG2223	nitrite transmembrane transporter activity
OSV15_RS04430	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OSV15_RS04435	COG1140	nitrate reductase beta subunit
OSV15_RS04440	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
OSV15_RS04445	COG2181	nitrate reductase activity
OSV15_RS04460	COG0521	Mo-molybdopterin cofactor biosynthetic process
OSV15_RS04475	COG1368	sulfuric ester hydrolase activity
OSV15_RS04490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OSV15_RS04495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OSV15_RS04500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OSV15_RS04505	COG2252	PERMEase
OSV15_RS04515	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OSV15_RS04515	COG3608	succinylglutamate desuccinylase aspartoacylase
OSV15_RS04525	COG2080	2 iron, 2 sulfur cluster binding
OSV15_RS04530	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OSV15_RS04535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OSV15_RS04560	COG0789	Transcriptional regulator
OSV15_RS04565	COG2813	Specifically methylates the guanine in position
OSV15_RS04600	COG0488	(ABC) transporter
OSV15_RS04605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OSV15_RS04610	COG2020	methyltransferase activity
OSV15_RS04630	COG2841	Protein conserved in bacteria
OSV15_RS04635	COG1970	mechanosensitive ion channel activity
OSV15_RS04645	COG1067	ATP-dependent peptidase activity
OSV15_RS04655	COG2862	Uncharacterized protein family, UPF0114
OSV15_RS04665	COG3046	protein related to deoxyribodipyrimidine photolyase
OSV15_RS04675	COG0545	Peptidyl-prolyl cis-trans isomerase
OSV15_RS04685	COG0142	geranyltranstransferase activity
OSV15_RS04690	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OSV15_RS04695	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OSV15_RS04700	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OSV15_RS04705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OSV15_RS04710	COG3045	CreA protein
OSV15_RS04715	COG0268	Binds directly to 16S ribosomal RNA
OSV15_RS04720	COG0728	peptidoglycan biosynthetic process
OSV15_RS04725	COG0196	riboflavin kinase activity
OSV15_RS04730	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OSV15_RS04735	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OSV15_RS04740	COG1047	Peptidyl-prolyl cis-trans
OSV15_RS04745	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OSV15_RS04790	COG0023	Translation Initiation Factor
OSV15_RS04805	COG0534	Mate efflux family protein
OSV15_RS04835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OSV15_RS04850	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OSV15_RS04850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OSV15_RS04855	COG1105	Belongs to the carbohydrate kinase PfkB family
OSV15_RS04860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OSV15_RS04860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OSV15_RS04860	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OSV15_RS04875	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OSV15_RS04880	COG0019	diaminopimelate decarboxylase activity
OSV15_RS04890	COG3128	pkhd-type hydroxylase
OSV15_RS04895	COG4774	siderophore transport
OSV15_RS04900	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OSV15_RS04920	COG4771	TonB-dependent receptor
OSV15_RS04935	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
OSV15_RS04945	COG0739	heme binding
OSV15_RS04960	COG0530	calcium, potassium:sodium antiporter activity
OSV15_RS04965	COG0530	calcium, potassium:sodium antiporter activity
OSV15_RS04975	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OSV15_RS04985	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OSV15_RS04990	COG1077	Cell shape determining protein MreB Mrl
OSV15_RS04995	COG1792	Involved in formation and maintenance of cell shape
OSV15_RS05015	COG1530	ribonuclease E activity
OSV15_RS05025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OSV15_RS05030	COG0312	modulator of DNA gyrase
OSV15_RS05040	COG0312	modulator of DNA gyrase
OSV15_RS05050	COG1660	Displays ATPase and GTPase activities
OSV15_RS05065	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OSV15_RS05070	COG1137	ATPase activity
OSV15_RS05085	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OSV15_RS05095	COG1127	ABC transporter
OSV15_RS05100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OSV15_RS05105	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OSV15_RS05130	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OSV15_RS05135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OSV15_RS05145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OSV15_RS05150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OSV15_RS05160	COG0175	sulfate reduction
OSV15_RS05170	COG4969	Belongs to the N-Me-Phe pilin family
OSV15_RS05185	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OSV15_RS05190	COG0237	dephospho-CoA kinase activity
OSV15_RS05205	COG0667	Aldo Keto reductase
OSV15_RS05210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OSV15_RS05215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OSV15_RS05220	COG0723	plastoquinol--plastocyanin reductase activity
OSV15_RS05225	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OSV15_RS05230	COG2857	Cytochrome c1
OSV15_RS05235	COG0625	glutathione transferase activity
OSV15_RS05240	COG2969	positive regulation of protein catabolic process
OSV15_RS05245	COG2823	Periplasmic or secreted lipoprotein
OSV15_RS05250	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OSV15_RS05255	COG0792	nuclease activity
OSV15_RS05280	COG0275	rRNA processing
OSV15_RS05295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OSV15_RS05300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OSV15_RS05305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OSV15_RS05310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OSV15_RS05315	COG0772	Belongs to the SEDS family
OSV15_RS05320	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OSV15_RS05325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OSV15_RS05330	COG1181	Belongs to the D-alanine--D-alanine ligase family
OSV15_RS05380	COG1285	pathogenesis
OSV15_RS05405	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS05410	COG0659	secondary active sulfate transmembrane transporter activity
OSV15_RS05465	COG0840	transmembrane signaling receptor activity
OSV15_RS05470	COG0501	Belongs to the peptidase M48B family
OSV15_RS05480	COG2119	membrane
OSV15_RS05485	COG2813	Specifically methylates the guanine in position
OSV15_RS05490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OSV15_RS05495	COG1280	lysine exporter protein (LysE YggA)
OSV15_RS05500	COG0318	PFAM AMP-dependent synthetase and ligase
OSV15_RS05510	COG4191	Histidine kinase
OSV15_RS05510	COG0784	Response regulator, receiver
OSV15_RS05515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OSV15_RS05520	COG2885	chlorophyll binding
OSV15_RS05525	COG0784	Response regulator, receiver
OSV15_RS05525	COG2205	protein histidine kinase activity
OSV15_RS05535	COG0204	Acyl-transferase
OSV15_RS05545	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OSV15_RS05555	COG0386	Belongs to the glutathione peroxidase family
OSV15_RS05560	COG1309	transcriptional regulator
OSV15_RS05570	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
OSV15_RS05585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OSV15_RS05590	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS05630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OSV15_RS05635	COG0693	protein deglycase activity
OSV15_RS05640	COG4628	conserved protein (DUF2132)
OSV15_RS05660	COG0469	pyruvate kinase activity
OSV15_RS05685	COG0714	Associated with various cellular activities
OSV15_RS05710	COG2925	Exonuclease
OSV15_RS05720	COG0788	formyltetrahydrofolate deformylase activity
OSV15_RS05730	COG0433	COG0433 Predicted ATPase
OSV15_RS05750	COG3022	response to hydroperoxide
OSV15_RS05755	COG1230	cation diffusion facilitator family transporter
OSV15_RS05760	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OSV15_RS05765	COG0315	cyclic pyranopterin monophosphate synthase activity
OSV15_RS05770	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OSV15_RS05790	COG0400	carboxylic ester hydrolase activity
OSV15_RS05795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OSV15_RS05800	COG4597	amino acid ABC transporter
OSV15_RS05805	COG0765	amino acid transport
OSV15_RS05810	COG1126	abc transporter atp-binding protein
OSV15_RS05830	COG3034	peptidoglycan biosynthetic process
OSV15_RS05855	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OSV15_RS05860	COG4536	flavin adenine dinucleotide binding
OSV15_RS05865	COG4137	Cytochrome C assembly protein
OSV15_RS05870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OSV15_RS05875	COG0228	four-way junction DNA binding
OSV15_RS05880	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OSV15_RS05885	COG0336	Belongs to the RNA methyltransferase TrmD family
OSV15_RS05890	COG0335	large ribosomal subunit rRNA binding
OSV15_RS05905	COG3791	Glutathione-dependent formaldehyde-activating
OSV15_RS05925	COG0418	dihydroorotase activity
OSV15_RS05935	COG0137	argininosuccinate synthase activity
OSV15_RS05940	COG0346	lactoylglutathione lyase activity
OSV15_RS05950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OSV15_RS05960	COG4659	FMN binding
OSV15_RS05965	COG4658	electron transport chain
OSV15_RS05975	COG2878	Part of a membrane complex involved in electron transport
OSV15_RS05980	COG4657	Part of a membrane complex involved in electron transport
OSV15_RS05990	COG1024	Enoyl-CoA hydratase
OSV15_RS06050	COG3086	response to oxidative stress
OSV15_RS06055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OSV15_RS06060	COG0481	GTPase activity
OSV15_RS06075	COG0571	ribonuclease III activity
OSV15_RS06085	COG1381	Involved in DNA repair and RecF pathway recombination
OSV15_RS06090	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OSV15_RS06100	COG0583	DNA-binding transcription factor activity
OSV15_RS06110	COG0500	methyltransferase
OSV15_RS06115	COG2226	methyltransferase
OSV15_RS06125	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OSV15_RS06140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OSV15_RS06155	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OSV15_RS06165	COG1414	Transcriptional regulator
OSV15_RS06170	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OSV15_RS06175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OSV15_RS06180	COG0183	Belongs to the thiolase family
OSV15_RS06185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OSV15_RS06285	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
OSV15_RS06295	COG0583	DNA-binding transcription factor activity
OSV15_RS06305	COG0583	DNA-binding transcription factor activity
OSV15_RS06365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OSV15_RS06660	COG2003	Belongs to the UPF0758 family
OSV15_RS06720	COG4644	lycopene metabolic process
OSV15_RS06745	COG0277	FAD linked oxidase domain protein
OSV15_RS06750	COG0582	viral genome integration into host DNA
OSV15_RS06770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OSV15_RS06770	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OSV15_RS06775	COG0489	protein tyrosine kinase activity
OSV15_RS06780	COG1278	Cold shock
OSV15_RS06785	COG0717	Belongs to the dCTP deaminase family
OSV15_RS06790	COG3005	denitrification pathway
OSV15_RS06800	COG0243	molybdopterin cofactor binding
OSV15_RS06810	COG4459	periplasmic nitrate reductase
OSV15_RS06815	COG2814	Major facilitator Superfamily
OSV15_RS06820	COG3091	SprT-like family
OSV15_RS06880	COG0789	Transcriptional regulator
OSV15_RS06885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OSV15_RS06890	COG1061	Type III restriction enzyme res subunit
OSV15_RS06895	COG1002	Type II restriction enzyme, methylase subunits
OSV15_RS06910	COG1061	Type III restriction enzyme res subunit
OSV15_RS06985	COG4772	TonB-dependent receptor
OSV15_RS07000	COG0789	Transcriptional regulator
OSV15_RS07015	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OSV15_RS07040	COG3039	Transposase
OSV15_RS07045	COG3039	Transposase
OSV15_RS07060	COG2124	cytochrome p450
OSV15_RS07085	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OSV15_RS07115	COG0789	Transcriptional regulator
OSV15_RS07125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OSV15_RS07175	COG2974	May be involved in recombination
OSV15_RS07190	COG3384	dioxygenase
OSV15_RS07200	COG0583	DNA-binding transcription factor activity
OSV15_RS07245	COG1250	3-hydroxyacyl-CoA dehydrogenase
OSV15_RS07250	COG1024	Enoyl-CoA hydratase
OSV15_RS07260	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS07345	COG0789	Transcriptional regulator
OSV15_RS07395	COG0037	tRNA processing
OSV15_RS07410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OSV15_RS07440	COG1294	oxidase, subunit
OSV15_RS07445	COG4890	Cyd operon protein YbgT
OSV15_RS07460	COG0791	NLP P60 protein
OSV15_RS07465	COG0791	NLP P60 protein
OSV15_RS07480	COG4206	TonB-dependent receptor
OSV15_RS07495	COG1797	cobyrinic acid a,c-diamide synthase activity
OSV15_RS07500	COG0778	Nitroreductase
OSV15_RS07510	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OSV15_RS07520	COG1492	cobalamin metabolic process
OSV15_RS07530	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OSV15_RS07540	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
OSV15_RS07550	COG0251	oxidation-reduction process
OSV15_RS07580	COG2067	long-chain fatty acid transport protein
OSV15_RS07595	COG3100	YcgL domain-containing protein
OSV15_RS07605	COG2983	Belongs to the UPF0260 family
OSV15_RS07615	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
OSV15_RS07620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OSV15_RS07625	COG0527	aspartate kinase activity
OSV15_RS07630	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OSV15_RS07655	COG2239	Acts as a magnesium transporter
OSV15_RS07660	COG3630	sodium ion export across plasma membrane
OSV15_RS07665	COG5016	pyruvate
OSV15_RS07665	COG0511	ligase activity, forming carbon-carbon bonds
OSV15_RS07670	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
OSV15_RS07695	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
OSV15_RS07715	COG0835	chemotaxis
OSV15_RS07715	COG0784	Response regulator, receiver
OSV15_RS07720	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OSV15_RS07725	COG1815	bacterial-type flagellum-dependent cell motility
OSV15_RS07735	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OSV15_RS07740	COG1749	Flagellar hook protein flgE
OSV15_RS07745	COG4787	bacterial-type flagellum-dependent cell motility
OSV15_RS07750	COG4786	Flagellar basal body rod
OSV15_RS07755	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
OSV15_RS07760	COG1706	bacterial-type flagellum-dependent cell motility
OSV15_RS07770	COG1256	bacterial-type flagellum assembly
OSV15_RS07780	COG1555	photosystem II stabilization
OSV15_RS07805	COG2200	EAL domain
OSV15_RS07820	COG1362	aminopeptidase activity
OSV15_RS07825	COG0564	pseudouridine synthase activity
OSV15_RS07830	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OSV15_RS07835	COG2894	cell division
OSV15_RS07840	COG0850	regulation of cytokinetic process
OSV15_RS07845	COG1560	Kdo2-lipid A biosynthetic process
OSV15_RS07855	COG2853	Lipoprotein
OSV15_RS07870	COG3162	membrane
OSV15_RS07875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OSV15_RS07895	COG3089	Belongs to the UPF0270 family
OSV15_RS07905	COG1363	Peptidase, m42
OSV15_RS07910	COG0189	ligase activity
OSV15_RS07910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OSV15_RS07915	COG0367	asparagine synthase
OSV15_RS07925	COG1404	Belongs to the peptidase S8 family
OSV15_RS07935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OSV15_RS07945	COG4221	oxidoreductase activity
OSV15_RS07955	COG1201	RNA secondary structure unwinding
OSV15_RS07990	COG2133	pyrroloquinoline quinone binding
OSV15_RS07995	COG4993	Dehydrogenase
OSV15_RS08000	COG2996	Protein conserved in bacteria
OSV15_RS08015	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OSV15_RS08065	COG4771	TonB-dependent receptor
OSV15_RS08095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OSV15_RS08105	COG1696	Membrane protein involved in D-alanine export
OSV15_RS08120	COG5002	protein histidine kinase activity
OSV15_RS08120	COG0784	Response regulator, receiver
OSV15_RS08120	COG2198	Histidine kinase
OSV15_RS08140	COG3842	ATPase activity
OSV15_RS08160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OSV15_RS08170	COG1295	ribonuclease BN
OSV15_RS08195	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OSV15_RS08200	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OSV15_RS08210	COG1546	Belongs to the CinA family
OSV15_RS08260	COG5642	Protein of unknown function (DUF2384)
OSV15_RS08335	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OSV15_RS08340	COG2137	regulation of response to DNA damage stimulus
OSV15_RS08350	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OSV15_RS08355	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
OSV15_RS08365	COG3148	PFAM DTW domain containing protein
OSV15_RS08370	COG0697	spore germination
OSV15_RS08380	COG0583	DNA-binding transcription factor activity
OSV15_RS08390	COG3012	SEC-C Motif Domain Protein
OSV15_RS08410	COG1199	ATP-dependent helicase activity
OSV15_RS08425	COG0259	pyridoxamine-phosphate oxidase activity
OSV15_RS08435	COG3133	Outer membrane lipoprotein
OSV15_RS08440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OSV15_RS08440	COG2111	Na H antiporter
OSV15_RS08445	COG1006	Multisubunit Na H antiporter MnhC subunit
OSV15_RS08450	COG0651	ATP synthesis coupled electron transport
OSV15_RS08460	COG2212	antiporter activity
OSV15_RS08465	COG1320	monovalent cation:proton antiporter activity
OSV15_RS08470	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OSV15_RS08475	COG0024	Methionine aminopeptidase
OSV15_RS08480	COG0052	Belongs to the universal ribosomal protein uS2 family
OSV15_RS08485	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OSV15_RS08490	COG0528	UMP kinase activity
OSV15_RS08495	COG0233	cytoplasmic translational termination
OSV15_RS08500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OSV15_RS08510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OSV15_RS08520	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OSV15_RS08535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OSV15_RS08540	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OSV15_RS08545	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OSV15_RS08550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OSV15_RS08560	COG0825	malonyl-CoA metabolic process
OSV15_RS08580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OSV15_RS08580	COG0446	pyridine nucleotide-disulphide oxidoreductase
OSV15_RS08595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OSV15_RS08625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OSV15_RS08630	COG2218	PFAM glutamate synthase alpha subunit domain protein
OSV15_RS08635	COG0069	glutamate synthase activity
OSV15_RS08640	COG0004	ammonium transporteR
OSV15_RS08650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OSV15_RS08660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OSV15_RS08665	COG2076	Multidrug Resistance protein
OSV15_RS08670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OSV15_RS08670	COG0519	Catalyzes the synthesis of GMP from XMP
OSV15_RS08675	COG1012	belongs to the aldehyde dehydrogenase family
OSV15_RS08690	COG0004	ammonium transporteR
OSV15_RS08705	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OSV15_RS08715	COG3850	Histidine kinase
OSV15_RS08720	COG2197	response regulator
OSV15_RS08735	COG0504	CTP synthase activity
OSV15_RS08740	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OSV15_RS08755	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OSV15_RS08770	COG0583	DNA-binding transcription factor activity
OSV15_RS08775	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OSV15_RS08780	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OSV15_RS08785	COG1902	pentaerythritol trinitrate reductase activity
OSV15_RS08795	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OSV15_RS08800	COG0585	pseudouridine synthase activity
OSV15_RS08805	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OSV15_RS08810	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OSV15_RS08865	COG0589	response to stress
OSV15_RS08875	COG0217	transcriptional regulatory protein
OSV15_RS08890	COG2258	MOSC domain
OSV15_RS08905	COG0004	ammonium transporteR
OSV15_RS08910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OSV15_RS08925	COG0483	inositol monophosphate 1-phosphatase activity
OSV15_RS08950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OSV15_RS08975	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OSV15_RS08995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OSV15_RS09010	COG0826	peptidase U32
OSV15_RS09070	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OSV15_RS09075	COG0583	DNA-binding transcription factor activity
OSV15_RS09080	COG2249	NAD(P)H dehydrogenase (quinone) activity
OSV15_RS09105	COG2226	methyltransferase
OSV15_RS09120	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OSV15_RS09125	COG0583	DNA-binding transcription factor activity
OSV15_RS09130	COG1943	Transposase
OSV15_RS09145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OSV15_RS09155	COG0745	RESPONSE REGULATOR receiver
OSV15_RS09160	COG2205	protein histidine kinase activity
OSV15_RS09170	COG0668	transmembrane transport
OSV15_RS09175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OSV15_RS09210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OSV15_RS09220	COG2988	succinylglutamate desuccinylase activity
OSV15_RS09225	COG1131	(ABC) transporter
OSV15_RS09230	COG0842	Transport permease protein
OSV15_RS09235	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OSV15_RS09235	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OSV15_RS09245	COG2853	Lipoprotein
OSV15_RS09255	COG0745	RESPONSE REGULATOR receiver
OSV15_RS09265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OSV15_RS09290	COG1335	isochorismatase
OSV15_RS09320	COG2814	Major facilitator Superfamily
OSV15_RS09325	COG4948	Mandelate Racemase Muconate Lactonizing
OSV15_RS09330	COG4829	muconolactone delta-isomerase
OSV15_RS09335	COG3485	protocatechuate 3,4-dioxygenase
OSV15_RS09340	COG3135	benzoate transporter
OSV15_RS09375	COG0114	fumarate hydratase activity
OSV15_RS09385	COG0271	Belongs to the BolA IbaG family
OSV15_RS09390	COG1054	Belongs to the UPF0176 family
OSV15_RS09405	COG0840	transmembrane signaling receptor activity
OSV15_RS09430	COG0583	DNA-binding transcription factor activity
OSV15_RS09435	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
OSV15_RS09440	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS09450	COG2079	MmgE PrpD family protein
OSV15_RS09460	COG2301	Belongs to the HpcH HpaI aldolase family
OSV15_RS09485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OSV15_RS09490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OSV15_RS09510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OSV15_RS09520	COG1770	oligopeptidase
OSV15_RS09525	COG1024	Enoyl-CoA hydratase
OSV15_RS09525	COG1250	3-hydroxyacyl-CoA dehydrogenase
OSV15_RS09530	COG0183	Belongs to the thiolase family
OSV15_RS09595	COG0653	protein targeting
OSV15_RS09615	COG0133	tryptophan synthase activity
OSV15_RS09620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OSV15_RS09625	COG1012	belongs to the aldehyde dehydrogenase family
OSV15_RS09630	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OSV15_RS09635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OSV15_RS09665	COG4964	Belongs to the GSP D family
OSV15_RS09720	COG1216	Glycosyl transferase, family 2
OSV15_RS09735	COG0297	glycogen (starch) synthase activity
OSV15_RS09825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OSV15_RS09830	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS09845	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OSV15_RS09850	COG0066	3-isopropylmalate dehydratase activity
OSV15_RS09880	COG0135	phosphoribosylanthranilate isomerase activity
OSV15_RS09885	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OSV15_RS09890	COG0285	dihydrofolate synthase activity
OSV15_RS09900	COG1286	toxin biosynthetic process
OSV15_RS09955	COG3383	formate dehydrogenase (NAD+) activity
OSV15_RS09965	COG0437	4 iron, 4 sulfur cluster binding
OSV15_RS10000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OSV15_RS10005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OSV15_RS10020	COG3038	cytochrome b561
OSV15_RS10025	COG0642	Histidine kinase
OSV15_RS10040	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS10075	COG3642	lipopolysaccharide core region biosynthetic process
OSV15_RS10095	COG1271	oxidase subunit
OSV15_RS10100	COG1294	oxidase, subunit
OSV15_RS10125	COG1902	pentaerythritol trinitrate reductase activity
OSV15_RS10125	COG0446	pyridine nucleotide-disulphide oxidoreductase
OSV15_RS10155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OSV15_RS10165	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OSV15_RS10170	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OSV15_RS10185	COG0573	inorganic phosphate transmembrane transporter activity
OSV15_RS10200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OSV15_RS10205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OSV15_RS10215	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OSV15_RS10230	COG2217	Heavy metal translocating P-type atpase
OSV15_RS10245	COG2010	Cytochrome c
OSV15_RS10260	COG3278	Belongs to the heme-copper respiratory oxidase family
OSV15_RS10265	COG2010	Cytochrome c
OSV15_RS10275	COG3278	Belongs to the heme-copper respiratory oxidase family
OSV15_RS10285	COG0840	transmembrane signaling receptor activity
OSV15_RS10295	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
OSV15_RS10315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OSV15_RS10320	COG2010	Cytochrome c
OSV15_RS10320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OSV15_RS10335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OSV15_RS10340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OSV15_RS10345	COG1196	nuclear chromosome segregation
OSV15_RS10350	COG3115	cell septum assembly
OSV15_RS10355	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OSV15_RS10360	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OSV15_RS10385	COG3123	guanosine phosphorylase activity
OSV15_RS10405	COG2009	succinate dehydrogenase
OSV15_RS10410	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OSV15_RS10415	COG1053	succinate dehydrogenase
OSV15_RS10420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OSV15_RS10440	COG0045	succinate-CoA ligase (ADP-forming) activity
OSV15_RS10480	COG0326	Molecular chaperone. Has ATPase activity
OSV15_RS10510	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
OSV15_RS10520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OSV15_RS10525	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OSV15_RS10560	COG0628	permease
OSV15_RS10570	COG0709	Synthesizes selenophosphate from selenide and ATP
OSV15_RS10575	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
OSV15_RS10585	COG0714	Associated with various cellular activities
OSV15_RS10615	COG1238	metal cluster binding
OSV15_RS10635	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS10645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OSV15_RS10655	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS10660	COG1024	Enoyl-CoA hydratase
OSV15_RS10690	COG0058	SHG alpha-glucan phosphorylase activity
OSV15_RS10720	COG4991	sh3 domain protein
OSV15_RS10725	COG0784	Response regulator, receiver
OSV15_RS10725	COG4191	Histidine kinase
OSV15_RS10730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OSV15_RS10750	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OSV15_RS10765	COG3447	MASE1 domain protein
OSV15_RS10765	COG5001	Diguanylate cyclase
OSV15_RS10765	COG5002	protein histidine kinase activity
OSV15_RS10805	COG0210	DNA helicase
OSV15_RS10810	COG0515	serine threonine protein kinase
OSV15_RS10820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OSV15_RS10820	COG2146	nitrite reductase [NAD(P)H] activity
OSV15_RS10825	COG2146	nitrite reductase [NAD(P)H] activity
OSV15_RS10825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OSV15_RS10845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OSV15_RS10860	COG4221	oxidoreductase activity
OSV15_RS10875	COG0789	Transcriptional regulator
OSV15_RS10880	COG3272	Protein of unknown function (DUF1722)
OSV15_RS10885	COG1090	epimerase
OSV15_RS10890	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OSV15_RS10895	COG5001	Diguanylate cyclase
OSV15_RS10895	COG3300	MHYT domain
OSV15_RS10900	COG1366	Belongs to the anti-sigma-factor antagonist family
OSV15_RS10920	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OSV15_RS10925	COG0302	gtp cyclohydrolase
OSV15_RS10940	COG0789	Transcriptional regulator
OSV15_RS10960	COG0784	Response regulator, receiver
OSV15_RS10960	COG2205	protein histidine kinase activity
OSV15_RS10965	COG0435	Glutathione S-transferase
OSV15_RS10970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OSV15_RS11025	COG0174	glutamine synthetase
OSV15_RS11030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OSV15_RS11035	COG1116	anion transmembrane transporter activity
OSV15_RS11040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OSV15_RS11050	COG1335	isochorismatase
OSV15_RS11070	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS11080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OSV15_RS11090	COG0668	transmembrane transport
OSV15_RS11100	COG0439	Biotin carboxylase
OSV15_RS11110	COG3665	Urea carboxylase-associated protein
OSV15_RS11115	COG3842	ATPase activity
OSV15_RS11130	COG0084	hydrolase, TatD family'
OSV15_RS11135	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OSV15_RS11155	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OSV15_RS11160	COG4181	ATPase activity
OSV15_RS11175	COG1376	ErfK ybiS ycfS ynhG family protein
OSV15_RS11190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OSV15_RS11195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OSV15_RS11210	COG0560	Phosphoserine phosphatase
OSV15_RS11235	COG1802	Transcriptional regulator
OSV15_RS11245	COG0372	Belongs to the citrate synthase family
OSV15_RS11260	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OSV15_RS11270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OSV15_RS11285	COG0668	transmembrane transport
OSV15_RS11320	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OSV15_RS11325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OSV15_RS11330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OSV15_RS11335	COG0215	cysteine-tRNA ligase activity
OSV15_RS11340	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OSV15_RS11370	COG0784	Response regulator, receiver
OSV15_RS11370	COG4191	Histidine kinase
OSV15_RS11375	COG2186	Transcriptional regulator
OSV15_RS11400	COG1764	response to oxidative stress
OSV15_RS11405	COG1846	Transcriptional regulator
OSV15_RS11415	COG2010	Cytochrome c
OSV15_RS11420	COG3256	nitric oxide reductase
OSV15_RS11425	COG0714	Associated with various cellular activities
OSV15_RS11430	COG4548	von Willebrand factor, type A
OSV15_RS11435	COG0544	peptidyl-prolyl cis-trans isomerase activity
OSV15_RS11445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OSV15_RS11450	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OSV15_RS11465	COG0167	dihydroorotate dehydrogenase activity
OSV15_RS11470	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OSV15_RS11510	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OSV15_RS11515	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
OSV15_RS11525	COG0535	radical SAM domain protein
OSV15_RS11540	COG0784	Response regulator, receiver
OSV15_RS11540	COG2205	protein histidine kinase activity
OSV15_RS11555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OSV15_RS11560	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OSV15_RS11615	COG0798	PFAM Bile acid sodium symporter
OSV15_RS11620	COG2072	flavoprotein involved in K transport
OSV15_RS11625	COG0640	Transcriptional regulator
OSV15_RS11630	COG0431	NADPH-dependent FMN reductase
OSV15_RS11640	COG1742	UPF0060 membrane protein
OSV15_RS11645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OSV15_RS11670	COG5642	Protein of unknown function (DUF2384)
OSV15_RS11695	COG0840	transmembrane signaling receptor activity
OSV15_RS11720	COG0459	protein refolding
OSV15_RS11730	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
OSV15_RS11825	COG2135	peptidase activity
OSV15_RS11905	COG3039	Transposase
OSV15_RS11955	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
OSV15_RS11960	COG1116	anion transmembrane transporter activity
OSV15_RS11965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OSV15_RS11970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OSV15_RS11970	COG1116	anion transmembrane transporter activity
OSV15_RS11975	COG0446	pyridine nucleotide-disulphide oxidoreductase
OSV15_RS12010	COG3039	Transposase
OSV15_RS12055	COG0789	Transcriptional regulator
OSV15_RS12085	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS12095	COG1024	Enoyl-CoA hydratase
OSV15_RS12100	COG1250	3-hydroxyacyl-CoA dehydrogenase
OSV15_RS12105	COG0183	Belongs to the thiolase family
OSV15_RS12140	COG3284	Transcriptional regulator
OSV15_RS12175	COG3039	Transposase
OSV15_RS12195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OSV15_RS12240	COG3039	Transposase
OSV15_RS12270	COG0583	DNA-binding transcription factor activity
OSV15_RS12285	COG0723	plastoquinol--plastocyanin reductase activity
OSV15_RS12285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OSV15_RS12315	COG3685	Protein conserved in bacteria
OSV15_RS12320	COG3264	Mechanosensitive ion channel
OSV15_RS12320	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
OSV15_RS12325	COG1546	Belongs to the CinA family
OSV15_RS12325	COG1058	Belongs to the CinA family
OSV15_RS12330	COG0297	glycogen (starch) synthase activity
OSV15_RS12335	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OSV15_RS12340	COG1640	4-alpha-glucanotransferase
OSV15_RS12360	COG0739	heme binding
OSV15_RS12370	COG3384	dioxygenase
OSV15_RS12375	COG0583	DNA-binding transcription factor activity
OSV15_RS12390	COG3568	Endonuclease Exonuclease Phosphatase
OSV15_RS12395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OSV15_RS12400	COG0392	lysyltransferase activity
OSV15_RS12405	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OSV15_RS12410	COG0366	Alpha amylase catalytic
OSV15_RS12430	COG2864	formate dehydrogenase
OSV15_RS12435	COG0437	4 iron, 4 sulfur cluster binding
OSV15_RS12455	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS12460	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS12460	COG3321	synthase
OSV15_RS12460	COG0604	alcohol dehydrogenase
OSV15_RS12490	COG1538	Outer membrane efflux protein
OSV15_RS12495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OSV15_RS12500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OSV15_RS12510	COG0728	peptidoglycan biosynthetic process
OSV15_RS12525	COG1115	amino acid carrier protein
OSV15_RS12530	COG2911	Protein conserved in bacteria
OSV15_RS12535	COG0729	surface antigen
OSV15_RS12550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OSV15_RS12565	COG1609	Transcriptional regulator
OSV15_RS12570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OSV15_RS12575	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OSV15_RS12580	COG3265	gluconokinase activity
OSV15_RS12585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OSV15_RS12590	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OSV15_RS12615	COG0488	(ABC) transporter
OSV15_RS12620	COG1968	undecaprenyl-diphosphatase activity
OSV15_RS12625	COG0840	transmembrane signaling receptor activity
OSV15_RS12640	COG2323	membrane
OSV15_RS12655	COG3706	GGDEF domain
OSV15_RS12660	COG2201	protein-glutamate methylesterase activity
OSV15_RS12665	COG0316	Belongs to the HesB IscA family
OSV15_RS12665	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OSV15_RS12705	COG2223	nitrite transmembrane transporter activity
OSV15_RS12710	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OSV15_RS12725	COG0071	Belongs to the small heat shock protein (HSP20) family
OSV15_RS12745	COG0604	alcohol dehydrogenase
OSV15_RS12750	COG0616	signal peptide processing
OSV15_RS12770	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS12785	COG2816	NAD+ diphosphatase activity
OSV15_RS12795	COG1024	Enoyl-CoA hydratase
OSV15_RS12805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OSV15_RS12810	COG0328	RNA-DNA hybrid ribonuclease activity
OSV15_RS12820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OSV15_RS12825	COG0741	lytic transglycosylase activity
OSV15_RS12825	COG1388	LysM domain
OSV15_RS12835	COG4166	transmembrane transport
OSV15_RS12845	COG4174	ABC transporter (Permease)
OSV15_RS12850	COG4239	(ABC) transporter, permease
OSV15_RS12855	COG4172	Belongs to the ABC transporter superfamily
OSV15_RS12940	COG3851	Histidine kinase
OSV15_RS12965	COG1131	(ABC) transporter
OSV15_RS12985	COG1648	precorrin-2 dehydrogenase activity
OSV15_RS12985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OSV15_RS12990	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OSV15_RS12995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OSV15_RS13000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OSV15_RS13005	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OSV15_RS13015	COG0492	ferredoxin-NADP+ reductase activity
OSV15_RS13020	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OSV15_RS13025	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OSV15_RS13030	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OSV15_RS13035	COG0542	response to heat
OSV15_RS13040	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OSV15_RS13065	COG0482	sulfurtransferase activity
OSV15_RS13070	COG2915	High frequency lysogenization protein hflD homolog
OSV15_RS13080	COG2850	peptidyl-arginine hydroxylation
OSV15_RS13085	COG2153	protein acetylation
OSV15_RS13110	COG0628	permease
OSV15_RS13115	COG2056	Na+-H+ antiporter family
OSV15_RS13120	COG0720	synthase
OSV15_RS13150	COG0402	S-adenosylhomocysteine deaminase activity
OSV15_RS13155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OSV15_RS13160	COG0546	phosphoglycolate phosphatase activity
OSV15_RS13165	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS13175	COG0800	Aldolase
OSV15_RS13200	COG2840	Smr protein MutS2
OSV15_RS13210	COG0625	glutathione transferase activity
OSV15_RS13215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OSV15_RS13230	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OSV15_RS13235	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OSV15_RS13245	COG0077	Prephenate dehydratase
OSV15_RS13245	COG1605	Chorismate mutase
OSV15_RS13250	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OSV15_RS13260	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OSV15_RS13275	COG0587	DNA-directed DNA polymerase activity
OSV15_RS13300	COG0028	Belongs to the TPP enzyme family
OSV15_RS13320	COG0776	regulation of translation
OSV15_RS13325	COG0072	phenylalanine-tRNA ligase activity
OSV15_RS13330	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OSV15_RS13335	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OSV15_RS13340	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OSV15_RS13345	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OSV15_RS13350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OSV15_RS13360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OSV15_RS13435	COG3171	Protein conserved in bacteria
OSV15_RS13440	COG2027	D-alanyl-D-alanine carboxypeptidase
OSV15_RS13445	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OSV15_RS13445	COG0116	Belongs to the methyltransferase superfamily
OSV15_RS13450	COG3130	regulation of translation
OSV15_RS13455	COG0167	dihydroorotate dehydrogenase activity
OSV15_RS13475	COG0714	Associated with various cellular activities
OSV15_RS13505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OSV15_RS13510	COG3707	response regulator
OSV15_RS13530	COG2223	nitrite transmembrane transporter activity
OSV15_RS13535	COG0515	serine threonine protein kinase
OSV15_RS13535	COG2815	serine threonine protein kinase
OSV15_RS13545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OSV15_RS13550	COG2146	nitrite reductase [NAD(P)H] activity
OSV15_RS13555	COG0243	molybdopterin cofactor binding
OSV15_RS13575	COG0308	aminopeptidase N
OSV15_RS13595	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OSV15_RS13600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OSV15_RS13630	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OSV15_RS13655	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OSV15_RS13665	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OSV15_RS13680	COG4580	involved in the transport of maltose and maltodextrins
OSV15_RS13685	COG3842	ATPase activity
OSV15_RS13690	COG0395	ABC-type sugar transport system, permease component
OSV15_RS13695	COG1175	transmembrane transport
OSV15_RS13700	COG1653	transport
OSV15_RS13725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OSV15_RS13735	COG0180	Tryptophanyl-tRNA synthetase
OSV15_RS13740	COG0009	L-threonylcarbamoyladenylate synthase
OSV15_RS13745	COG0613	PHP domain protein
OSV15_RS13750	COG2350	Protein conserved in bacteria
OSV15_RS13760	COG0745	RESPONSE REGULATOR receiver
OSV15_RS13770	COG0642	Histidine kinase
OSV15_RS13775	COG0778	Nitroreductase
OSV15_RS13780	COG0727	PFAM Uncharacterised protein family (UPF0153)
OSV15_RS13785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OSV15_RS13790	COG2354	Protein conserved in bacteria
OSV15_RS13810	COG2207	Transcriptional regulator
OSV15_RS13825	COG1752	Esterase of the alpha-beta hydrolase superfamily
OSV15_RS13835	COG0514	ATP-dependent DNA helicase (RecQ)
OSV15_RS13845	COG2832	Protein of unknown function (DUF454)
OSV15_RS13865	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
OSV15_RS13875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OSV15_RS13885	COG0542	response to heat
OSV15_RS13905	COG0121	glutamine amidotransferase
OSV15_RS13915	COG0589	response to stress
OSV15_RS13925	COG0488	(ABC) transporter
OSV15_RS13930	COG0741	lytic transglycosylase activity
OSV15_RS13935	COG0633	Ferredoxin
OSV15_RS13935	COG3217	Mosc domain protein beta barrel domain protein
OSV15_RS13940	COG3437	response regulator, receiver
OSV15_RS13950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OSV15_RS13955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OSV15_RS13960	COG0489	protein tyrosine kinase activity
OSV15_RS13960	COG3206	protein involved in exopolysaccharide biosynthesis
OSV15_RS13965	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OSV15_RS14005	COG0183	Belongs to the thiolase family
OSV15_RS14015	COG2977	Belongs to the P-Pant transferase superfamily
OSV15_RS14025	COG0776	regulation of translation
OSV15_RS14035	COG0840	transmembrane signaling receptor activity
OSV15_RS14040	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OSV15_RS14045	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OSV15_RS14050	COG0471	metal ion transport
OSV15_RS14055	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OSV15_RS14070	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
OSV15_RS14090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OSV15_RS14095	COG4591	ABC-type transport system involved in lipoprotein release permease component
OSV15_RS14100	COG1136	(ABC) transporter
OSV15_RS14140	COG0640	Transcriptional regulator
OSV15_RS14195	COG0629	single-stranded DNA binding
OSV15_RS14265	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OSV15_RS14485	COG2003	Belongs to the UPF0758 family
OSV15_RS14540	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OSV15_RS14540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OSV15_RS14545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OSV15_RS14550	COG1252	NADH dehydrogenase
OSV15_RS14555	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OSV15_RS14610	COG0583	DNA-binding transcription factor activity
OSV15_RS14620	COG0583	DNA-binding transcription factor activity
OSV15_RS14635	COG0582	viral genome integration into host DNA
OSV15_RS14655	COG0625	glutathione transferase activity
OSV15_RS14665	COG0386	Belongs to the glutathione peroxidase family
OSV15_RS14670	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OSV15_RS14675	COG0436	Aminotransferase
OSV15_RS14685	COG0501	Belongs to the peptidase M48B family
OSV15_RS14695	COG0500	methyltransferase
OSV15_RS14745	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OSV15_RS14775	COG2257	FlhB HrpN YscU SpaS Family
OSV15_RS14790	COG0835	chemotaxis
OSV15_RS14800	COG1192	Involved in chromosome partitioning
OSV15_RS14805	COG1360	Flagellar Motor Protein
OSV15_RS14810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OSV15_RS14815	COG2201	protein-glutamate methylesterase activity
OSV15_RS14820	COG0643	Histidine kinase
OSV15_RS14820	COG0784	Response regulator, receiver
OSV15_RS14820	COG2198	Histidine kinase
OSV15_RS14825	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
OSV15_RS14850	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OSV15_RS14855	COG2032	superoxide dismutase activity
OSV15_RS14870	COG1987	bacterial-type flagellum assembly
OSV15_RS14910	COG0745	RESPONSE REGULATOR receiver
OSV15_RS14945	COG1677	Flagellar hook-basal body complex protein FliE
OSV15_RS14950	COG3135	benzoate transporter
OSV15_RS14960	COG2130	NADP-dependent
OSV15_RS14975	COG5001	Diguanylate cyclase
OSV15_RS14975	COG3300	MHYT domain
OSV15_RS14985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OSV15_RS15045	COG1113	amino acid transport
OSV15_RS15050	COG0084	hydrolase, TatD family'
OSV15_RS15065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OSV15_RS15070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OSV15_RS15080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OSV15_RS15085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OSV15_RS15100	COG0416	fatty acid biosynthetic process
OSV15_RS15105	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OSV15_RS15120	COG0616	signal peptide processing
OSV15_RS15120	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OSV15_RS15135	COG1530	ribonuclease E activity
OSV15_RS15140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OSV15_RS15145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OSV15_RS15150	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OSV15_RS15155	COG2835	tetraacyldisaccharide 4'-kinase activity
OSV15_RS15160	COG1663	tetraacyldisaccharide 4'-kinase activity
OSV15_RS15170	COG0811	peptide transport
OSV15_RS15175	COG0658	competence protein
OSV15_RS15175	COG2333	competence protein COMEC
OSV15_RS15190	COG1136	(ABC) transporter
OSV15_RS15195	COG4591	ABC-type transport system involved in lipoprotein release permease component
OSV15_RS15210	COG0584	glycerophosphoryl diester phosphodiesterase
OSV15_RS15215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OSV15_RS15225	COG1477	protein flavinylation
OSV15_RS15235	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OSV15_RS15250	COG1805	sodium ion transport
OSV15_RS15265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OSV15_RS15275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OSV15_RS15290	COG1793	dna ligase
OSV15_RS15295	COG1201	RNA secondary structure unwinding
OSV15_RS15325	COG3956	TIGRFAM MazG family protein
OSV15_RS15330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OSV15_RS15335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OSV15_RS15350	COG2860	membrane
OSV15_RS15355	COG0784	Response regulator, receiver
OSV15_RS15355	COG2205	protein histidine kinase activity
OSV15_RS15355	COG5002	protein histidine kinase activity
OSV15_RS15360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OSV15_RS15360	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
OSV15_RS15380	COG0583	DNA-binding transcription factor activity
OSV15_RS15395	COG0513	Belongs to the DEAD box helicase family
OSV15_RS15435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OSV15_RS15440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OSV15_RS15445	COG2226	methyltransferase
OSV15_RS15470	COG1131	(ABC) transporter
OSV15_RS15475	COG0456	acetyltransferase
OSV15_RS15505	COG2937	Belongs to the GPAT DAPAT family
OSV15_RS15510	COG0456	acetyltransferase
OSV15_RS15525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OSV15_RS15540	COG0642	Histidine kinase
OSV15_RS15580	COG2132	Multicopper oxidase
OSV15_RS15635	COG1472	Belongs to the glycosyl hydrolase 3 family
OSV15_RS15645	COG1346	cytolysis
OSV15_RS15650	COG1380	Effector of murein hydrolase LrgA
OSV15_RS15660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OSV15_RS15680	COG1309	transcriptional regulator
OSV15_RS15690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OSV15_RS15700	COG0742	ribosomal rna small subunit methyltransferase
OSV15_RS15725	COG0563	adenylate kinase activity
OSV15_RS15730	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OSV15_RS15770	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OSV15_RS15785	COG1902	pentaerythritol trinitrate reductase activity
OSV15_RS15790	COG3383	formate dehydrogenase (NAD+) activity
OSV15_RS15795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OSV15_RS15805	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OSV15_RS15810	COG1984	allophanate hydrolase subunit 2
OSV15_RS15835	COG0545	Peptidyl-prolyl cis-trans isomerase
OSV15_RS15850	COG2974	May be involved in recombination
OSV15_RS15855	COG2814	Major facilitator Superfamily
OSV15_RS15875	COG2205	protein histidine kinase activity
OSV15_RS15880	COG3174	membrane
OSV15_RS15915	COG0417	DNA replication proofreading
OSV15_RS16090	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
OSV15_RS16280	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OSV15_RS16290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OSV15_RS16300	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OSV15_RS16310	COG0425	Belongs to the sulfur carrier protein TusA family
OSV15_RS16320	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OSV15_RS16325	COG0427	acetyl-CoA hydrolase
OSV15_RS16335	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OSV15_RS16340	COG0602	queuosine metabolic process
OSV15_RS16345	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
OSV15_RS16350	COG2885	chlorophyll binding
OSV15_RS16375	COG0824	Thioesterase
OSV15_RS16380	COG2255	four-way junction helicase activity
OSV15_RS16385	COG0632	four-way junction helicase activity
OSV15_RS16390	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OSV15_RS16400	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OSV15_RS16405	COG0783	Belongs to the Dps family
OSV15_RS16415	COG2900	Belongs to the SlyX family
OSV15_RS16430	COG0442	prolyl-tRNA aminoacylation
OSV15_RS16460	COG1295	ribonuclease BN
OSV15_RS16465	COG1393	Belongs to the ArsC family
OSV15_RS16480	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OSV15_RS16485	COG0628	permease
OSV15_RS16495	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OSV15_RS16500	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OSV15_RS16515	COG0436	Aminotransferase
OSV15_RS16535	COG1393	Belongs to the ArsC family
OSV15_RS16540	COG2171	N-acyltransferase activity
OSV15_RS16545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OSV15_RS16560	COG3258	Cytochrome c
OSV15_RS16565	COG2863	cytochrome
OSV15_RS16575	COG3530	Putative quorum-sensing-regulated virulence factor
OSV15_RS16590	COG3706	GGDEF domain
OSV15_RS16595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OSV15_RS16605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OSV15_RS16615	COG0583	DNA-binding transcription factor activity
OSV15_RS16620	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS16630	COG1280	lysine exporter protein (LysE YggA)
OSV15_RS16650	COG1462	curli production assembly transport component CsgG
OSV15_RS16670	COG1309	transcriptional regulator
OSV15_RS16680	COG0189	ligase activity
OSV15_RS16680	COG4067	protein conserved in archaea
OSV15_RS16685	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OSV15_RS16685	COG0116	Belongs to the methyltransferase superfamily
OSV15_RS16690	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OSV15_RS16700	COG3321	synthase
OSV15_RS16700	COG0604	alcohol dehydrogenase
OSV15_RS16710	COG3284	Transcriptional regulator
OSV15_RS16725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OSV15_RS16730	COG1063	alcohol dehydrogenase
OSV15_RS16735	COG0022	dehydrogenase e1 component
OSV15_RS16740	COG0508	dehydrogenase complex catalyzes the overall conversion of
OSV15_RS16745	COG0508	dehydrogenase complex catalyzes the overall conversion of
OSV15_RS16765	COG0625	glutathione transferase activity
OSV15_RS16785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OSV15_RS16795	COG0431	NADPH-dependent FMN reductase
OSV15_RS16800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OSV15_RS16805	COG0640	Transcriptional regulator
OSV15_RS16810	COG0798	PFAM Bile acid sodium symporter
OSV15_RS16825	COG1280	lysine exporter protein (LysE YggA)
OSV15_RS16845	COG4191	Histidine kinase
OSV15_RS16845	COG0784	Response regulator, receiver
OSV15_RS16860	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
OSV15_RS16865	COG4191	Histidine kinase
OSV15_RS16865	COG0784	Response regulator, receiver
OSV15_RS16885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OSV15_RS16895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OSV15_RS16905	COG4221	oxidoreductase activity
OSV15_RS16915	COG2207	Transcriptional regulator
OSV15_RS16920	COG3845	ABC transporter
OSV15_RS16925	COG4603	Belongs to the binding-protein-dependent transport system permease family
OSV15_RS16930	COG1079	Belongs to the binding-protein-dependent transport system permease family
OSV15_RS16955	COG1301	dicarboxylic acid transport
OSV15_RS16965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OSV15_RS16970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OSV15_RS16980	COG0471	metal ion transport
OSV15_RS16980	COG0490	domain, Protein
OSV15_RS17005	COG2814	Major facilitator Superfamily
OSV15_RS17035	COG2207	Transcriptional regulator
OSV15_RS17040	COG1279	arginine transmembrane transporter activity
OSV15_RS17060	COG2733	membrane
OSV15_RS17080	COG0537	adenosine 5'-monophosphoramidase activity
OSV15_RS17085	COG2258	MOSC domain
OSV15_RS17100	COG3795	YCII-related domain
OSV15_RS17125	COG1234	tRNA 3'-trailer cleavage
OSV15_RS17135	COG0631	protein serine/threonine phosphatase activity
OSV15_RS17140	COG0515	serine threonine protein kinase
OSV15_RS17140	COG2815	serine threonine protein kinase
OSV15_RS17160	COG1643	Atp-dependent helicase
OSV15_RS17180	COG0318	PFAM AMP-dependent synthetase and ligase
OSV15_RS17185	COG0318	PFAM AMP-dependent synthetase and ligase
OSV15_RS17190	COG2030	dehydratase
OSV15_RS17215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OSV15_RS17225	COG0443	Heat shock 70 kDa protein
OSV15_RS17230	COG2271	Major facilitator Superfamily
OSV15_RS17235	COG3622	Belongs to the hyi family
OSV15_RS17240	COG2084	Dehydrogenase
OSV15_RS17245	COG1968	undecaprenyl-diphosphatase activity
OSV15_RS17250	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
OSV15_RS17260	COG3639	organic phosphonate transmembrane transporter activity
OSV15_RS17265	COG3639	organic phosphonate transmembrane transporter activity
OSV15_RS17355	COG2165	general secretion pathway protein
OSV15_RS17360	COG2165	general secretion pathway protein
OSV15_RS17365	COG1459	type II secretion system
OSV15_RS17370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OSV15_RS17380	COG3267	Type II secretory pathway component ExeA
OSV15_RS17380	COG3409	Peptidoglycan-binding domain 1 protein
OSV15_RS17410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OSV15_RS17445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OSV15_RS17450	COG0556	nucleotide-excision repair
OSV15_RS17470	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OSV15_RS17480	COG3842	ATPase activity
OSV15_RS17485	COG0590	tRNA wobble adenosine to inosine editing
OSV15_RS17505	COG2948	multi-organism process
OSV15_RS17520	COG3846	protein secretion by the type IV secretion system
OSV15_RS17535	COG3451	type IV secretory pathway VirB4
OSV15_RS17545	COG3838	Conjugal transfer protein Trbc
OSV15_RS17570	COG0583	DNA-binding transcription factor activity
OSV15_RS17580	COG1024	Enoyl-CoA hydratase
OSV15_RS17580	COG1250	3-hydroxyacyl-CoA dehydrogenase
OSV15_RS17590	COG1017	nitric oxide dioxygenase activity
OSV15_RS17590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OSV15_RS17595	COG0318	PFAM AMP-dependent synthetase and ligase
OSV15_RS17620	COG1309	transcriptional regulator
OSV15_RS17625	COG1012	belongs to the aldehyde dehydrogenase family
OSV15_RS17630	COG0446	pyridine nucleotide-disulphide oxidoreductase
OSV15_RS17630	COG1902	pentaerythritol trinitrate reductase activity
OSV15_RS17665	COG1192	Involved in chromosome partitioning
OSV15_RS17700	COG5489	Protein of unknown function (DUF736)
OSV15_RS17730	COG2003	Belongs to the UPF0758 family
OSV15_RS17735	COG3621	Patatin-like phospholipase
OSV15_RS17775	COG0582	viral genome integration into host DNA
OSV15_RS17780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OSV15_RS17780	COG0519	Catalyzes the synthesis of GMP from XMP
OSV15_RS17795	COG1570	exodeoxyribonuclease VII activity
OSV15_RS17800	COG0739	heme binding
OSV15_RS17810	COG0668	transmembrane transport
OSV15_RS17825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OSV15_RS17830	COG1064	alcohol dehydrogenase
OSV15_RS17840	COG2356	endonuclease I
OSV15_RS17845	COG3647	Membrane
OSV15_RS17860	COG0436	Aminotransferase
OSV15_RS17870	COG1160	GTP binding
OSV15_RS17880	COG2976	Protein conserved in bacteria
OSV15_RS17885	COG0124	histidyl-tRNA synthetase
OSV15_RS17890	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OSV15_RS17905	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OSV15_RS17910	COG0105	UTP biosynthetic process
OSV15_RS17925	COG0443	Heat shock 70 kDa protein
OSV15_RS17930	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OSV15_RS17935	COG0316	Belongs to the HesB IscA family
OSV15_RS17945	COG1104	cysteine desulfurase activity
OSV15_RS17970	COG3134	Outer membrane lipoprotein
OSV15_RS17985	COG1862	Preprotein translocase
OSV15_RS18005	COG1278	Cold shock
OSV15_RS18015	COG0795	lipopolysaccharide-transporting ATPase activity
OSV15_RS18020	COG0795	lipopolysaccharide-transporting ATPase activity
OSV15_RS18025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OSV15_RS18055	COG0471	metal ion transport
OSV15_RS18055	COG0490	domain, Protein
OSV15_RS18060	COG0477	Major facilitator Superfamily
OSV15_RS18065	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
OSV15_RS18085	COG3081	Nucleoid-associated protein
OSV15_RS18090	COG2326	polyphosphate kinase activity
OSV15_RS18110	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OSV15_RS18115	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OSV15_RS18155	COG0402	S-adenosylhomocysteine deaminase activity
OSV15_RS18160	COG0803	Belongs to the bacterial solute-binding protein 9 family
OSV15_RS18170	COG1121	(ABC) transporter
OSV15_RS18175	COG1802	Transcriptional regulator
OSV15_RS18180	COG2252	PERMEase
OSV15_RS18205	COG4266	Belongs to the allantoicase family
OSV15_RS18210	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OSV15_RS18220	COG2233	PERMEase
OSV15_RS18225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OSV15_RS18225	COG4651	solute:proton antiporter activity
OSV15_RS18230	COG2233	PERMEase
OSV15_RS18245	COG0840	transmembrane signaling receptor activity
OSV15_RS18265	COG0708	Exodeoxyribonuclease III
OSV15_RS18285	COG2351	hydroxyisourate hydrolase activity
OSV15_RS18290	COG0583	DNA-binding transcription factor activity
OSV15_RS18295	COG3960	tartronate-semialdehyde synthase activity
OSV15_RS18300	COG3622	Belongs to the hyi family
OSV15_RS18305	COG2084	Dehydrogenase
OSV15_RS18315	COG0469	pyruvate kinase activity
OSV15_RS18320	COG4413	Urea transporter
OSV15_RS18350	COG3706	GGDEF domain
OSV15_RS18355	COG4625	pathogenesis
OSV15_RS18355	COG3240	lipase activity
OSV15_RS18370	COG0583	DNA-binding transcription factor activity
OSV15_RS18375	COG1279	arginine transmembrane transporter activity
OSV15_RS18395	COG1704	LemA family
OSV15_RS18425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OSV15_RS18430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OSV15_RS18440	COG0459	protein refolding
OSV15_RS18445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OSV15_RS18450	COG3030	protein affecting phage T7 exclusion by the F plasmid
OSV15_RS18460	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS18480	COG0668	transmembrane transport
OSV15_RS18485	COG1666	GTP binding
OSV15_RS18490	COG0745	RESPONSE REGULATOR receiver
OSV15_RS18505	COG2096	Adenosyltransferase
OSV15_RS18535	COG0494	nUDIX hydrolase
OSV15_RS18540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OSV15_RS18545	COG0653	protein targeting
OSV15_RS18585	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OSV15_RS18590	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OSV15_RS18610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OSV15_RS18615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OSV15_RS18625	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OSV15_RS18630	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OSV15_RS18640	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OSV15_RS18645	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OSV15_RS18665	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OSV15_RS18690	COG0559	Belongs to the binding-protein-dependent transport system permease family
OSV15_RS18720	COG0318	PFAM AMP-dependent synthetase and ligase
OSV15_RS18725	COG4294	response to UV
OSV15_RS18730	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS18735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OSV15_RS18740	COG1024	Enoyl-CoA hydratase
OSV15_RS18770	COG0789	Transcriptional regulator
OSV15_RS18775	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OSV15_RS18785	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OSV15_RS18800	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OSV15_RS18835	COG0697	spore germination
OSV15_RS18840	COG0288	reversible hydration of carbon dioxide
OSV15_RS18860	COG0456	acetyltransferase
OSV15_RS18870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OSV15_RS18880	COG0019	diaminopimelate decarboxylase activity
OSV15_RS18900	COG3008	intermembrane lipid transfer
OSV15_RS18905	COG2995	paraquat-inducible protein a
OSV15_RS18910	COG2995	paraquat-inducible protein a
OSV15_RS18940	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
OSV15_RS18950	COG1183	phosphatidylcholine synthase activity
OSV15_RS18955	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OSV15_RS18965	COG0028	Belongs to the TPP enzyme family
OSV15_RS18985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OSV15_RS18995	COG2226	methyltransferase
OSV15_RS19020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OSV15_RS19035	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OSV15_RS19050	COG2264	protein methyltransferase activity
OSV15_RS19070	COG0138	bifunctional purine biosynthesis protein purh
OSV15_RS19080	COG0784	Response regulator, receiver
OSV15_RS19080	COG5002	protein histidine kinase activity
OSV15_RS19080	COG2205	protein histidine kinase activity
OSV15_RS19085	COG2124	cytochrome p450
OSV15_RS19090	COG0392	lysyltransferase activity
OSV15_RS19100	COG0679	Auxin Efflux Carrier
OSV15_RS19115	COG0436	Aminotransferase
OSV15_RS19120	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OSV15_RS19125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OSV15_RS19135	COG3852	Histidine kinase
OSV15_RS19140	COG2204	response regulator
OSV15_RS19155	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OSV15_RS19160	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OSV15_RS19165	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OSV15_RS19170	COG0166	Belongs to the GPI family
OSV15_RS19200	COG1185	polyribonucleotide nucleotidyltransferase activity
OSV15_RS19205	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OSV15_RS19210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OSV15_RS19215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OSV15_RS19220	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OSV15_RS19225	COG0195	Participates in both transcription termination and antitermination
OSV15_RS19225	COG2251	uridine kinase activity
OSV15_RS19230	COG0779	Required for maturation of 30S ribosomal subunits
OSV15_RS19245	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OSV15_RS19250	COG0149	triose-phosphate isomerase activity
OSV15_RS19255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OSV15_RS19260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OSV15_RS19270	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OSV15_RS19295	COG0505	Belongs to the CarA family
OSV15_RS19300	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OSV15_RS19305	COG0484	heat shock protein binding
OSV15_RS19310	COG0443	Heat shock 70 kDa protein
OSV15_RS19315	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OSV15_RS19320	COG0497	DNA recombination
OSV15_RS19335	COG2914	Belongs to the UPF0125 (RnfH) family
OSV15_RS19345	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OSV15_RS19355	COG1620	l-lactate permease
OSV15_RS19360	COG0247	lactate metabolic process
OSV15_RS19365	COG1139	Iron-sulfur cluster binding protein
OSV15_RS19390	COG1715	Restriction endonuclease
OSV15_RS19405	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OSV15_RS19415	COG0784	Response regulator, receiver
OSV15_RS19415	COG4191	Histidine kinase
OSV15_RS19420	COG3842	ATPase activity
OSV15_RS19425	COG0366	Alpha amylase catalytic
OSV15_RS19445	COG3833	ABC-type maltose transport systems, permease component
OSV15_RS19450	COG1175	transmembrane transport
OSV15_RS19460	COG0366	Alpha amylase catalytic
OSV15_RS19475	COG4580	involved in the transport of maltose and maltodextrins
OSV15_RS19495	COG4989	oxidoreductase activity
OSV15_RS19505	COG0800	Aldolase
OSV15_RS19520	COG1737	Transcriptional regulator
OSV15_RS19540	COG2814	Major facilitator Superfamily
OSV15_RS19590	COG3154	lipid carrier protein
OSV15_RS19595	COG0826	peptidase U32
OSV15_RS19600	COG0826	peptidase U32
OSV15_RS19610	COG3604	Transcriptional regulator
OSV15_RS19650	COG3256	nitric oxide reductase
OSV15_RS19655	COG2010	Cytochrome c
OSV15_RS19680	COG3391	amine dehydrogenase activity
OSV15_RS19685	COG2010	Cytochrome c
OSV15_RS19700	COG0714	Associated with various cellular activities
OSV15_RS19705	COG1845	cytochrome c oxidase, subunit III
OSV15_RS19715	COG0535	radical SAM domain protein
OSV15_RS19720	COG1648	precorrin-2 dehydrogenase activity
OSV15_RS19720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OSV15_RS19740	COG3278	Belongs to the heme-copper respiratory oxidase family
OSV15_RS19750	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS19770	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OSV15_RS19785	COG4263	nitrous-oxide reductase activity
OSV15_RS19790	COG0348	domain, Protein
OSV15_RS19790	COG3901	Regulator of nitric oxide reductase transcription
OSV15_RS19795	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS19810	COG3189	MarR family transcriptional regulator
OSV15_RS19820	COG0492	ferredoxin-NADP+ reductase activity
OSV15_RS19825	COG1760	l-serine dehydratase
OSV15_RS19840	COG2154	pterin-4-alpha-carbinolamine dehydratase
OSV15_RS19855	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
OSV15_RS19860	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OSV15_RS19865	COG0402	S-adenosylhomocysteine deaminase activity
OSV15_RS19875	COG1607	acyl-coa hydrolase
OSV15_RS19880	COG2824	Alkylphosphonate utilization operon protein PhnA
OSV15_RS19885	COG1278	Cold shock
OSV15_RS19895	COG3706	GGDEF domain
OSV15_RS19930	COG0346	lactoylglutathione lyase activity
OSV15_RS19935	COG1253	flavin adenine dinucleotide binding
OSV15_RS19945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OSV15_RS19955	COG4977	sequence-specific DNA binding
OSV15_RS19995	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OSV15_RS20005	COG2814	Major facilitator Superfamily
OSV15_RS20010	COG1309	transcriptional regulator
OSV15_RS20020	COG2217	Heavy metal translocating P-type atpase
OSV15_RS20030	COG0840	transmembrane signaling receptor activity
OSV15_RS20045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OSV15_RS20060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OSV15_RS20060	COG2169	Transcriptional regulator
OSV15_RS20070	COG0084	hydrolase, TatD family'
OSV15_RS20075	COG0840	transmembrane signaling receptor activity
OSV15_RS20085	COG3023	N-Acetylmuramoyl-L-alanine amidase
OSV15_RS20090	COG1515	deoxyribonuclease V activity
OSV15_RS20100	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OSV15_RS20105	COG0180	Tryptophanyl-tRNA synthetase
OSV15_RS20110	COG2945	thiolester hydrolase activity
OSV15_RS20135	COG1252	NADH dehydrogenase
OSV15_RS20215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OSV15_RS20220	COG0305	Participates in initiation and elongation during chromosome replication
OSV15_RS20225	COG0359	binds to the 23S rRNA
OSV15_RS20235	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OSV15_RS20240	COG0360	Binds together with S18 to 16S ribosomal RNA
OSV15_RS20245	COG0784	Response regulator, receiver
OSV15_RS20245	COG4191	Histidine kinase
OSV15_RS20250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OSV15_RS20255	COG0557	exoribonuclease II activity
OSV15_RS20270	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OSV15_RS20275	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OSV15_RS20280	COG0330	HflC and HflK could
OSV15_RS20285	COG0330	HflC and HflK could
OSV15_RS20290	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OSV15_RS20295	COG1923	regulation of RNA biosynthetic process
OSV15_RS20300	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OSV15_RS20305	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OSV15_RS20310	COG0860	N-Acetylmuramoyl-L-alanine amidase
OSV15_RS20315	COG0802	atpase or kinase
OSV15_RS20320	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OSV15_RS20320	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OSV15_RS20345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OSV15_RS20355	COG0531	amino acid
OSV15_RS20360	COG4303	Ethanolamine ammonia lyase large subunit
OSV15_RS20375	COG3228	Belongs to the MtfA family
OSV15_RS20385	COG1253	flavin adenine dinucleotide binding
OSV15_RS20400	COG2197	response regulator
OSV15_RS20405	COG3851	Histidine kinase
OSV15_RS20415	COG0745	RESPONSE REGULATOR receiver
OSV15_RS20425	COG2198	Histidine kinase
OSV15_RS20425	COG0643	Histidine kinase
OSV15_RS20430	COG0840	transmembrane signaling receptor activity
OSV15_RS20435	COG0835	chemotaxis
OSV15_RS20455	COG5001	Diguanylate cyclase
OSV15_RS20455	COG3300	MHYT domain
OSV15_RS20465	COG0076	glutamate decarboxylase activity
OSV15_RS20470	COG3486	L-lysine 6-monooxygenase (NADPH) activity
OSV15_RS20495	COG1722	exodeoxyribonuclease VII activity
OSV15_RS20500	COG0142	geranyltranstransferase activity
OSV15_RS20505	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OSV15_RS20525	COG1028	Short-chain dehydrogenase reductase Sdr
OSV15_RS20565	COG1643	Atp-dependent helicase
OSV15_RS20580	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OSV15_RS20610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OSV15_RS20610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OSV15_RS20665	COG0789	Transcriptional regulator
OSV15_RS20690	COG3039	Transposase
OSV15_RS20730	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OSV15_RS20770	COG4221	oxidoreductase activity
OSV15_RS20795	COG2132	Multicopper oxidase
OSV15_RS20830	COG1643	Atp-dependent helicase
OSV15_RS20845	COG1522	sequence-specific DNA binding
OSV15_RS20890	COG0829	nickel cation binding
OSV15_RS20895	COG0831	urea catabolic process
OSV15_RS20905	COG0832	Belongs to the urease beta subunit family
OSV15_RS20910	COG0804	urea catabolic process
OSV15_RS20920	COG1953	Uracil, thiamine, allantoin
OSV15_RS20930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OSV15_RS20940	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OSV15_RS20955	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
OSV15_RS20960	COG0830	nickel cation binding
OSV15_RS20965	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OSV15_RS20980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OSV15_RS20985	COG0427	acetyl-CoA hydrolase
OSV15_RS20990	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS20995	COG2205	protein histidine kinase activity
OSV15_RS20995	COG3437	response regulator, receiver
OSV15_RS20995	COG3850	Histidine kinase
OSV15_RS20995	COG4999	Histidine kinase
OSV15_RS21000	COG0351	phosphomethylpyrimidine kinase
OSV15_RS21005	COG0352	thiamine-phosphate diphosphorylase activity
OSV15_RS21010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OSV15_RS21025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OSV15_RS21030	COG1702	phosphate starvation-inducible protein PhoH
OSV15_RS21035	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OSV15_RS21040	COG4535	Mg2 and Co2 transporter CorC
OSV15_RS21045	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OSV15_RS21060	COG0495	leucyl-tRNA aminoacylation
OSV15_RS21075	COG3036	rescue of stalled ribosome
OSV15_RS21080	COG2951	lytic endotransglycosylase activity
OSV15_RS21090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OSV15_RS21095	COG0321	lipoyl(octanoyl) transferase activity
OSV15_RS21100	COG2921	Belongs to the UPF0250 family
OSV15_RS21105	COG1686	Belongs to the peptidase S11 family
OSV15_RS21115	COG2951	lytic endotransglycosylase activity
OSV15_RS21120	COG0772	Belongs to the SEDS family
OSV15_RS21125	COG0768	penicillin binding
OSV15_RS21130	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OSV15_RS21140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OSV15_RS21145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OSV15_RS21150	COG0586	Pfam SNARE associated Golgi protein
OSV15_RS21155	COG2267	carboxylic ester hydrolase activity
OSV15_RS21165	COG1346	cytolysis
OSV15_RS21185	COG0702	epimerase
OSV15_RS21190	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OSV15_RS21200	COG1162	GTPase activity
OSV15_RS21205	COG1360	Flagellar Motor Protein
OSV15_RS21210	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OSV15_RS21225	COG0688	phosphatidylethanolamine metabolic process
OSV15_RS21240	COG1063	alcohol dehydrogenase
OSV15_RS21245	COG3830	Belongs to the UPF0237 family
OSV15_RS21245	COG0560	Phosphoserine phosphatase
OSV15_RS21280	COG3150	esterase
OSV15_RS21285	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OSV15_RS21295	COG0494	nUDIX hydrolase
OSV15_RS21310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OSV15_RS21320	COG0730	response to heat
OSV15_RS21335	COG1459	type II secretion system
OSV15_RS21345	COG2165	general secretion pathway protein
OSV15_RS21400	COG1216	Glycosyl transferase, family 2
OSV15_RS21400	COG0463	Glycosyl transferase, family 2
OSV15_RS21430	COG1088	dTDP-glucose 4,6-dehydratase activity
OSV15_RS21445	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OSV15_RS21450	COG1538	Outer membrane efflux protein
OSV15_RS21455	COG1519	Transferase
OSV15_RS21470	COG0667	Aldo Keto reductase
OSV15_RS21480	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OSV15_RS21480	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OSV15_RS21495	COG1132	(ABC) transporter
OSV15_RS21515	COG3562	capsule polysaccharide
OSV15_RS21525	COG1215	transferase activity, transferring glycosyl groups
OSV15_RS21530	COG2192	nodulation
OSV15_RS21555	COG0438	transferase activity, transferring glycosyl groups
OSV15_RS21560	COG0859	PFAM glycosyl transferase family 9
OSV15_RS21565	COG0859	PFAM glycosyl transferase family 9
OSV15_RS21575	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OSV15_RS21600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OSV15_RS21605	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS21610	COG3706	GGDEF domain
OSV15_RS21615	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS21635	COG1073	alpha beta
OSV15_RS21635	COG2226	methyltransferase
OSV15_RS21640	COG0156	8-amino-7-oxononanoate synthase activity
OSV15_RS21645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OSV15_RS21650	COG1040	competence protein
OSV15_RS21655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OSV15_RS21660	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OSV15_RS21695	COG1304	FMN binding
OSV15_RS21705	COG1960	acyl-CoA dehydrogenase activity
OSV15_RS21710	COG3263	regulation of cellular component size
OSV15_RS21715	COG1196	nuclear chromosome segregation
OSV15_RS21715	COG3264	Mechanosensitive ion channel
OSV15_RS21720	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OSV15_RS21735	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OSV15_RS21740	COG4999	Histidine kinase
OSV15_RS21740	COG3850	Histidine kinase
OSV15_RS21740	COG3437	response regulator, receiver
OSV15_RS21740	COG2205	protein histidine kinase activity
OSV15_RS21770	COG0330	HflC and HflK could
OSV15_RS21840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OSV15_RS21855	COG0513	Belongs to the DEAD box helicase family
OSV15_RS21860	COG1289	transmembrane transporter activity
OSV15_RS21870	COG2081	HI0933 family
OSV15_RS21910	COG0191	fructose-bisphosphate aldolase activity
OSV15_RS21925	COG0126	phosphoglycerate kinase activity
OSV15_RS21930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OSV15_RS21935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OSV15_RS21940	COG0583	DNA-binding transcription factor activity
OSV15_RS21945	COG2175	clavaminate synthase activity
OSV15_RS21955	COG2226	methyltransferase
OSV15_RS21960	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OSV15_RS21965	COG0842	Transport permease protein
OSV15_RS21970	COG1131	(ABC) transporter
OSV15_RS21975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OSV15_RS21980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OSV15_RS22005	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OSV15_RS22010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OSV15_RS22015	COG0513	Belongs to the DEAD box helicase family
OSV15_RS22030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OSV15_RS22035	COG2353	YceI-like domain
OSV15_RS22040	COG3038	cytochrome b561
OSV15_RS22050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OSV15_RS22065	COG2198	Histidine kinase
OSV15_RS22065	COG0784	Response regulator, receiver
OSV15_RS22065	COG0643	Histidine kinase
OSV15_RS22105	COG1678	Uncharacterized ACR, COG1678
OSV15_RS22110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OSV15_RS22120	COG0540	Belongs to the ATCase OTCase family
OSV15_RS22175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OSV15_RS22180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OSV15_RS22180	COG2813	Specifically methylates the guanine in position
OSV15_RS22190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OSV15_RS22195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OSV15_RS22220	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OSV15_RS22235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OSV15_RS22240	COG2022	thiamine diphosphate biosynthetic process
OSV15_RS22250	COG2363	Small membrane protein
OSV15_RS22255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OSV15_RS22275	COG2177	Part of the ABC transporter FtsEX involved in
OSV15_RS22280	COG2884	Cell division ATP-binding protein ftsE
OSV15_RS22285	COG0552	protein localization to endoplasmic reticulum
OSV15_RS22290	COG0612	Peptidase, M16
OSV15_RS22295	COG0612	Peptidase, M16
OSV15_RS22300	COG0742	ribosomal rna small subunit methyltransferase
OSV15_RS22330	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OSV15_RS22335	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OSV15_RS22340	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OSV15_RS22360	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OSV15_RS22370	COG0693	protein deglycase activity
OSV15_RS22385	COG0129	dihydroxy-acid dehydratase activity
OSV15_RS22410	COG0584	glycerophosphoryl diester phosphodiesterase
OSV15_RS22420	COG1160	GTP binding
OSV15_RS22435	COG0704	Plays a role in the regulation of phosphate uptake
OSV15_RS22440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OSV15_RS22445	COG0573	inorganic phosphate transmembrane transporter activity
OSV15_RS22465	COG2203	Gaf domain
OSV15_RS22465	COG3706	GGDEF domain
OSV15_RS22465	COG4251	negative regulation of phosphorylation
OSV15_RS22465	COG5001	Diguanylate cyclase
OSV15_RS22480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OSV15_RS22485	COG1074	ATP-dependent DNA helicase activity
OSV15_RS22490	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OSV15_RS22500	COG1283	sodium-dependent phosphate transmembrane transporter activity
OSV15_RS22515	COG2358	TRAP transporter, solute receptor (TAXI family
OSV15_RS22530	COG0840	transmembrane signaling receptor activity
OSV15_RS22535	COG2203	Gaf domain
OSV15_RS22535	COG3706	GGDEF domain
OSV15_RS22535	COG4251	negative regulation of phosphorylation
OSV15_RS22535	COG5001	Diguanylate cyclase
OSV15_RS22575	COG3180	Ammonia monooxygenase
OSV15_RS22580	COG0700	Nucleoside recognition
OSV15_RS22600	COG2204	response regulator
OSV15_RS22605	COG5002	protein histidine kinase activity
OSV15_RS22615	COG3023	N-Acetylmuramoyl-L-alanine amidase
OSV15_RS22640	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OSV15_RS22645	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OSV15_RS22645	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OSV15_RS22660	COG1178	ABC-type Fe3 transport system permease component
OSV15_RS22670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OSV15_RS22680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OSV15_RS22685	COG0006	proline dipeptidase activity
OSV15_RS22690	COG3079	Belongs to the UPF0149 family
OSV15_RS22710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OSV15_RS22735	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OSV15_RS22745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OSV15_RS22750	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OSV15_RS22755	COG4942	peptidase
OSV15_RS22760	COG0793	Belongs to the peptidase S41A family
OSV15_RS22765	COG2861	carbohydrate metabolic process
OSV15_RS22780	COG0107	imidazoleglycerol-phosphate synthase activity
OSV15_RS22785	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OSV15_RS22800	COG0131	Imidazoleglycerol-phosphate dehydratase
OSV15_RS22805	COG3707	response regulator
OSV15_RS22810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OSV15_RS22820	COG1116	anion transmembrane transporter activity
OSV15_RS22835	COG1194	a g-specific adenine glycosylase
OSV15_RS22840	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
OSV15_RS22855	COG1525	nuclease
OSV15_RS22885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OSV15_RS22895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OSV15_RS22910	COG0676	glucose-6-phosphate 1-epimerase activity
OSV15_RS22965	COG2204	response regulator
OSV15_RS23005	COG3220	belongs to the UPF0276 family
OSV15_RS23015	COG1595	DNA-templated transcription, initiation
OSV15_RS23020	COG4944	Protein of unknown function (DUF1109)
OSV15_RS23045	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OSV15_RS23065	COG3052	prosthetic group binding
OSV15_RS23070	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OSV15_RS23080	COG4221	oxidoreductase activity
OSV15_RS23090	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
OSV15_RS23095	COG3639	organic phosphonate transmembrane transporter activity
OSV15_RS23100	COG2188	Transcriptional regulator
OSV15_RS23105	COG3624	Phosphonate C-P lyase system protein PhnG
OSV15_RS23115	COG3626	phosphonate metabolism
OSV15_RS23120	COG3627	carbon phosphorus lyase activity
OSV15_RS23125	COG4107	phosphonate C-P lyase system protein PhnK
OSV15_RS23130	COG4778	phosphonate C-P lyase system protein PhnL
OSV15_RS23135	COG3454	Phosphonate metabolism
OSV15_RS23145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OSV15_RS23160	COG2358	TRAP transporter, solute receptor (TAXI family
OSV15_RS23200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OSV15_RS23210	COG3360	Dodecin
OSV15_RS23215	COG4249	Peptidase C14 caspase catalytic subunit p20
OSV15_RS23220	COG1132	(ABC) transporter
OSV15_RS23240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OSV15_RS23245	COG1404	Belongs to the peptidase S8 family
OSV15_RS23260	COG0159	tryptophan synthase activity
OSV15_RS23275	COG3550	peptidyl-serine autophosphorylation
OSV15_RS23280	COG1396	sequence-specific DNA binding
OSV15_RS23285	COG0625	glutathione transferase activity
OSV15_RS23300	COG3340	Belongs to the peptidase S51 family
OSV15_RS23305	COG1132	(ABC) transporter
OSV15_RS23325	COG2323	membrane
OSV15_RS23330	COG0583	DNA-binding transcription factor activity
OSV15_RS23365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OSV15_RS23395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OSV15_RS23400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OSV15_RS23405	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
OSV15_RS23430	COG1612	heme a metabolic process
OSV15_RS23435	COG0109	protoheme IX farnesyltransferase activity
OSV15_RS23460	COG1595	DNA-templated transcription, initiation
OSV15_RS23475	COG0523	cobalamin synthesis protein
OSV15_RS23490	COG4251	negative regulation of phosphorylation
OSV15_RS23495	COG0784	Response regulator, receiver
OSV15_RS23500	COG0784	Response regulator, receiver
OSV15_RS23500	COG4191	Histidine kinase
OSV15_RS23515	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OSV15_RS23520	COG1349	DNA-binding transcription factor activity
OSV15_RS23525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OSV15_RS23530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OSV15_RS23535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OSV15_RS23540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OSV15_RS23545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OSV15_RS23550	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OSV15_RS23555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OSV15_RS23565	COG0356	it plays a direct role in the translocation of protons across the membrane
OSV15_RS23575	COG1475	DNA binding
OSV15_RS23580	COG1192	Involved in chromosome partitioning
OSV15_RS23585	COG0357	Ribosomal RNA small subunit methyltransferase G
OSV15_RS23590	COG0445	tRNA wobble uridine modification
OSV15_RS23595	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OSV15_RS23600	COG0706	membrane insertase activity
OSV15_RS23605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OSV15_RS23610	COG0594	ribonuclease P activity
OSV15_RS23615	COG0230	Belongs to the bacterial ribosomal protein bL34 family