locus-tag	class	description
CH92_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CH92_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CH92_RS00040	COG0751	glycine-tRNA ligase activity
CH92_RS00045	COG0752	glycyl-tRNA synthetase alpha subunit
CH92_RS00050	COG2818	Glycosylase
CH92_RS00070	COG1126	abc transporter atp-binding protein
CH92_RS00075	COG0765	amino acid transport
CH92_RS00080	COG0765	amino acid transport
CH92_RS00085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH92_RS00090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH92_RS00095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH92_RS00100	COG2423	ornithine cyclodeaminase activity
CH92_RS00105	COG0006	proline dipeptidase activity
CH92_RS00110	COG3608	succinylglutamate desuccinylase aspartoacylase
CH92_RS00115	COG1522	sequence-specific DNA binding
CH92_RS00120	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH92_RS00125	COG1012	belongs to the aldehyde dehydrogenase family
CH92_RS00130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CH92_RS00135	COG0569	domain protein
CH92_RS00140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CH92_RS00145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CH92_RS00150	COG0242	peptide deformylase activity
CH92_RS00155	COG1652	LysM domain
CH92_RS00165	COG0009	L-threonylcarbamoyladenylate synthase
CH92_RS00175	COG0408	coproporphyrinogen oxidase activity
CH92_RS00180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH92_RS00195	COG1686	Belongs to the peptidase S11 family
CH92_RS00205	COG4221	oxidoreductase activity
CH92_RS00205	COG3321	synthase
CH92_RS00205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH92_RS00205	COG0604	alcohol dehydrogenase
CH92_RS00230	COG0662	Cupin 2, conserved barrel domain protein
CH92_RS00260	COG0662	Cupin 2, conserved barrel domain protein
CH92_RS00285	COG1132	(ABC) transporter
CH92_RS00295	COG3340	Belongs to the peptidase S51 family
CH92_RS00320	COG0625	glutathione transferase activity
CH92_RS00325	COG0667	Aldo Keto reductase
CH92_RS00345	COG0159	tryptophan synthase activity
CH92_RS00350	COG0133	tryptophan synthase activity
CH92_RS00360	COG1404	Belongs to the peptidase S8 family
CH92_RS00385	COG1132	(ABC) transporter
CH92_RS00390	COG4249	Peptidase C14 caspase catalytic subunit p20
CH92_RS00395	COG3360	Dodecin
CH92_RS00405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH92_RS00445	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH92_RS00450	COG2207	Transcriptional regulator
CH92_RS00460	COG0339	signal peptide processing
CH92_RS00490	COG0659	secondary active sulfate transmembrane transporter activity
CH92_RS00500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH92_RS00505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH92_RS00510	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CH92_RS00540	COG0109	protoheme IX farnesyltransferase activity
CH92_RS00555	COG3720	iron ion transport
CH92_RS00565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH92_RS00575	COG3675	Pfam Lipase (class 3)
CH92_RS00595	COG2011	ABC-type metal ion transport system permease component
CH92_RS00610	COG1451	nucleotide metabolic process
CH92_RS00615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH92_RS00620	COG1121	(ABC) transporter
CH92_RS00625	COG0735	belongs to the Fur family
CH92_RS00630	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH92_RS00645	COG1611	Belongs to the LOG family
CH92_RS00695	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH92_RS00765	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH92_RS00770	COG0583	DNA-binding transcription factor activity
CH92_RS00820	COG2706	6-phosphogluconolactonase activity
CH92_RS00830	COG4191	Histidine kinase
CH92_RS00830	COG0784	Response regulator, receiver
CH92_RS00845	COG3795	YCII-related domain
CH92_RS00850	COG4941	Belongs to the sigma-70 factor family
CH92_RS00855	COG2204	response regulator
CH92_RS00865	COG0659	secondary active sulfate transmembrane transporter activity
CH92_RS00870	COG0589	response to stress
CH92_RS00875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH92_RS00895	COG3276	selenocysteine insertion sequence binding
CH92_RS00900	COG1921	L-seryl-tRNASec selenium transferase activity
CH92_RS00910	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CH92_RS00915	COG0210	DNA helicase
CH92_RS00940	COG0527	aspartate kinase activity
CH92_RS00945	COG5285	phytanoyl-CoA dioxygenase
CH92_RS00950	COG1917	Cupin 2, conserved barrel domain protein
CH92_RS00955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH92_RS00960	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH92_RS00990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_RS00995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH92_RS01010	COG0765	amino acid transport
CH92_RS01015	COG0765	amino acid transport
CH92_RS01025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH92_RS01060	COG0583	DNA-binding transcription factor activity
CH92_RS01065	COG0439	Biotin carboxylase
CH92_RS01070	COG5016	pyruvate
CH92_RS01070	COG0511	ligase activity, forming carbon-carbon bonds
CH92_RS01085	COG2066	Belongs to the glutaminase family
CH92_RS01110	COG0058	SHG alpha-glucan phosphorylase activity
CH92_RS01115	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CH92_RS01145	COG1490	D-aminoacyl-tRNA deacylase activity
CH92_RS01165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH92_RS01170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH92_RS01175	COG0140	phosphoribosyl-ATP diphosphatase activity
CH92_RS01180	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH92_RS01185	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CH92_RS01195	COG2226	methyltransferase
CH92_RS01210	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CH92_RS01220	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH92_RS01235	COG3852	Histidine kinase
CH92_RS01255	COG0301	tRNA thio-modification
CH92_RS01255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH92_RS01260	COG1217	gtp-binding protein TYPA
CH92_RS01270	COG0784	Response regulator, receiver
CH92_RS01270	COG2198	Histidine kinase
CH92_RS01270	COG2205	protein histidine kinase activity
CH92_RS01280	COG0583	DNA-binding transcription factor activity
CH92_RS01290	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CH92_RS01295	COG3493	citrate carrier protein
CH92_RS01300	COG3290	protein histidine kinase activity
CH92_RS01305	COG4565	transcriptional regulatory protein
CH92_RS01330	COG2819	hydrolase of the alpha beta superfamily
CH92_RS01345	COG2207	Transcriptional regulator
CH92_RS01350	COG0583	DNA-binding transcription factor activity
CH92_RS01380	COG5001	Diguanylate cyclase
CH92_RS01380	COG3706	GGDEF domain
CH92_RS01380	COG4251	negative regulation of phosphorylation
CH92_RS01380	COG2203	Gaf domain
CH92_RS01390	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CH92_RS01410	COG4807	Protein conserved in bacteria
CH92_RS01425	COG2204	response regulator
CH92_RS01430	COG5001	Diguanylate cyclase
CH92_RS01435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH92_RS01465	COG4589	Belongs to the CDS family
CH92_RS01475	COG0351	phosphomethylpyrimidine kinase
CH92_RS01495	COG1320	monovalent cation:proton antiporter activity
CH92_RS01510	COG0651	ATP synthesis coupled electron transport
CH92_RS01515	COG0651	ATP synthesis coupled electron transport
CH92_RS01520	COG2111	Na H antiporter
CH92_RS01520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH92_RS01525	COG0840	transmembrane signaling receptor activity
CH92_RS01540	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS01575	COG2197	response regulator
CH92_RS01595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH92_RS01600	COG0277	FAD linked oxidase domain protein
CH92_RS01605	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH92_RS01620	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH92_RS01625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH92_RS01645	COG0494	nUDIX hydrolase
CH92_RS01650	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CH92_RS01660	COG0730	response to heat
CH92_RS01665	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CH92_RS01670	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CH92_RS01675	COG1192	Involved in chromosome partitioning
CH92_RS01685	COG0559	Belongs to the binding-protein-dependent transport system permease family
CH92_RS01710	COG0739	heme binding
CH92_RS01715	COG1253	flavin adenine dinucleotide binding
CH92_RS01730	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CH92_RS01735	COG3161	chorismate lyase activity
CH92_RS01740	COG2186	Transcriptional regulator
CH92_RS01745	COG0277	FAD linked oxidase domain protein
CH92_RS01750	COG0277	FAD linked oxidase domain protein
CH92_RS01755	COG0247	lactate metabolic process
CH92_RS01760	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CH92_RS01765	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH92_RS01770	COG1620	l-lactate permease
CH92_RS01820	COG0583	DNA-binding transcription factor activity
CH92_RS01825	COG1960	acyl-CoA dehydrogenase activity
CH92_RS01830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CH92_RS01835	COG1704	LemA family
CH92_RS01850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH92_RS01860	COG0489	protein tyrosine kinase activity
CH92_RS01870	COG2855	membrane
CH92_RS01885	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CH92_RS01905	COG2188	Transcriptional regulator
CH92_RS01915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH92_RS01930	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH92_RS01940	COG2885	chlorophyll binding
CH92_RS01945	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CH92_RS01955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH92_RS01960	COG1758	RNA polymerase activity
CH92_RS01970	COG1561	YicC-like family, N-terminal region
CH92_RS01975	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CH92_RS01985	COG0708	Exodeoxyribonuclease III
CH92_RS01990	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CH92_RS02000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CH92_RS02010	COG0756	dUTP diphosphatase activity
CH92_RS02015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH92_RS02020	COG2003	Belongs to the UPF0758 family
CH92_RS02035	COG1250	3-hydroxyacyl-CoA dehydrogenase
CH92_RS02055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH92_RS02060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH92_RS02070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH92_RS02095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CH92_RS02110	COG0366	Alpha amylase catalytic
CH92_RS02125	COG1454	alcohol dehydrogenase
CH92_RS02135	COG1414	Transcriptional regulator
CH92_RS02150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH92_RS02155	COG0606	chelatase, subunit chli
CH92_RS02160	COG2960	long-chain fatty acid transporting porin activity
CH92_RS02165	COG0347	Belongs to the P(II) protein family
CH92_RS02170	COG0004	ammonium transporteR
CH92_RS02175	COG0004	ammonium transporteR
CH92_RS02180	COG0432	Pfam Uncharacterised protein family UPF0047
CH92_RS02195	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH92_RS02205	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CH92_RS02220	COG1965	Belongs to the frataxin family
CH92_RS02225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH92_RS02260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CH92_RS02265	COG0165	Argininosuccinate lyase
CH92_RS02275	COG0745	RESPONSE REGULATOR receiver
CH92_RS02275	COG2972	Histidine kinase
CH92_RS02305	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CH92_RS02325	COG0488	(ABC) transporter
CH92_RS02335	COG0861	Integral membrane protein TerC family
CH92_RS02345	COG1671	Belongs to the UPF0178 family
CH92_RS02350	COG2050	protein possibly involved in aromatic compounds catabolism
CH92_RS02355	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH92_RS02365	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH92_RS02385	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CH92_RS02400	COG0018	arginyl-trna synthetase
CH92_RS02405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH92_RS02410	COG0254	rRNA binding
CH92_RS02420	COG0281	malic enzyme
CH92_RS02455	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CH92_RS02460	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CH92_RS02470	COG0070	glutamate synthase
CH92_RS02470	COG0069	glutamate synthase activity
CH92_RS02470	COG0067	glutamate synthase
CH92_RS02475	COG0493	'glutamate synthase
CH92_RS02495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH92_RS02500	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS02510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH92_RS02540	COG2986	histidine ammonia-lyase
CH92_RS02565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH92_RS02570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH92_RS02585	COG3118	belongs to the thioredoxin family
CH92_RS02595	COG2814	Major facilitator Superfamily
CH92_RS02660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH92_RS02665	COG0358	DNA primase activity
CH92_RS02670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CH92_RS02675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CH92_RS02680	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CH92_RS02700	COG2719	SpoVR family
CH92_RS02705	COG2718	Belongs to the UPF0229 family
CH92_RS02710	COG2766	serine protein kinase
CH92_RS02715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH92_RS02720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CH92_RS02725	COG2967	ApaG domain
CH92_RS02730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CH92_RS02735	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CH92_RS02740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH92_RS02745	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH92_RS02750	COG3178	'Phosphotransferase
CH92_RS02755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CH92_RS02775	COG2197	response regulator
CH92_RS02780	COG3842	ATPase activity
CH92_RS02790	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH92_RS02800	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH92_RS02805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH92_RS02810	COG0546	phosphoglycolate phosphatase activity
CH92_RS02820	COG0512	Glutamine amidotransferase of anthranilate synthase
CH92_RS02825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH92_RS02830	COG0134	indole-3-glycerol-phosphate synthase activity
CH92_RS02840	COG1765	OsmC-like protein
CH92_RS02850	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CH92_RS02855	COG0537	adenosine 5'-monophosphoramidase activity
CH92_RS02860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CH92_RS02870	COG2070	2-Nitropropane dioxygenase
CH92_RS02875	COG1981	membrane
CH92_RS02880	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CH92_RS02885	COG0316	Belongs to the HesB IscA family
CH92_RS02890	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CH92_RS02895	COG0739	heme binding
CH92_RS02900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CH92_RS02960	COG0515	serine threonine protein kinase
CH92_RS02960	COG2815	serine threonine protein kinase
CH92_RS03000	COG3675	Pfam Lipase (class 3)
CH92_RS03020	COG3604	Transcriptional regulator
CH92_RS03095	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CH92_RS03095	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CH92_RS03100	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CH92_RS03150	COG0081	regulation of translation
CH92_RS03160	COG0222	ribosome binding
CH92_RS03165	COG0085	RNA polymerase activity
CH92_RS03170	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CH92_RS03175	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH92_RS03180	COG0049	tRNA binding
CH92_RS03185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CH92_RS03195	COG0051	transcription antitermination factor activity, RNA binding
CH92_RS03200	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CH92_RS03205	COG0088	Forms part of the polypeptide exit tunnel
CH92_RS03210	COG0089	rRNA binding
CH92_RS03215	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CH92_RS03220	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH92_RS03225	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CH92_RS03230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CH92_RS03235	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH92_RS03240	COG0255	Belongs to the universal ribosomal protein uL29 family
CH92_RS03245	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH92_RS03250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH92_RS03255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CH92_RS03260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CH92_RS03265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CH92_RS03270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CH92_RS03275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CH92_RS03285	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CH92_RS03290	COG1841	ribosomal large subunit assembly
CH92_RS03295	COG0200	Binds to the 23S rRNA
CH92_RS03305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH92_RS03310	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CH92_RS03315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CH92_RS03320	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH92_RS03325	COG0202	RNA polymerase activity
CH92_RS03330	COG0203	ribosomal protein L17
CH92_RS03345	COG2814	Major facilitator Superfamily
CH92_RS03360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH92_RS03365	COG3047	cAMP biosynthetic process
CH92_RS03375	COG0811	peptide transport
CH92_RS03380	COG0811	peptide transport
CH92_RS03385	COG0848	biopolymer transport protein
CH92_RS03425	COG2321	neutral zinc metallopeptidase
CH92_RS03460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CH92_RS03465	COG2252	PERMEase
CH92_RS03475	COG2080	2 iron, 2 sulfur cluster binding
CH92_RS03480	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CH92_RS03485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CH92_RS03500	COG0789	Transcriptional regulator
CH92_RS03505	COG2813	Specifically methylates the guanine in position
CH92_RS03520	COG3119	arylsulfatase activity
CH92_RS03560	COG4176	ABC-type proline glycine betaine transport system permease component
CH92_RS03565	COG4175	Glycine betaine
CH92_RS03575	COG1760	l-serine dehydratase
CH92_RS03595	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CH92_RS03600	COG0247	lactate metabolic process
CH92_RS03600	COG2181	nitrate reductase activity
CH92_RS03605	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH92_RS03605	COG1902	pentaerythritol trinitrate reductase activity
CH92_RS03630	COG3246	L-lysine catabolic process to acetate
CH92_RS03645	COG1063	alcohol dehydrogenase
CH92_RS03680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH92_RS03680	COG1017	nitric oxide dioxygenase activity
CH92_RS03695	COG3265	gluconokinase activity
CH92_RS03720	COG0488	(ABC) transporter
CH92_RS03730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CH92_RS03770	COG1970	mechanosensitive ion channel activity
CH92_RS03775	COG1067	ATP-dependent peptidase activity
CH92_RS03785	COG2862	Uncharacterized protein family, UPF0114
CH92_RS03790	COG0545	Peptidyl-prolyl cis-trans isomerase
CH92_RS03800	COG0142	geranyltranstransferase activity
CH92_RS03805	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CH92_RS03810	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CH92_RS03815	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CH92_RS03820	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CH92_RS03825	COG3045	CreA protein
CH92_RS03830	COG0268	Binds directly to 16S ribosomal RNA
CH92_RS03835	COG0728	peptidoglycan biosynthetic process
CH92_RS03840	COG0196	riboflavin kinase activity
CH92_RS03845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CH92_RS03855	COG1047	Peptidyl-prolyl cis-trans
CH92_RS03860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CH92_RS03900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH92_RS03905	COG0023	Translation Initiation Factor
CH92_RS03910	COG1166	arginine decarboxylase activity
CH92_RS03915	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CH92_RS03925	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH92_RS03930	COG1522	sequence-specific DNA binding
CH92_RS03945	COG0733	neurotransmitter:sodium symporter activity
CH92_RS03955	COG0625	glutathione transferase activity
CH92_RS03960	COG0733	neurotransmitter:sodium symporter activity
CH92_RS03970	COG0693	protein deglycase activity
CH92_RS03980	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS03990	COG2154	pterin-4-alpha-carbinolamine dehydratase
CH92_RS04010	COG1760	l-serine dehydratase
CH92_RS04015	COG0492	ferredoxin-NADP+ reductase activity
CH92_RS04030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH92_RS04045	COG3189	MarR family transcriptional regulator
CH92_RS04055	COG1960	acyl-CoA dehydrogenase activity
CH92_RS04075	COG0517	IMP dehydrogenase activity
CH92_RS04075	COG1125	glycine betaine transport
CH92_RS04100	COG3604	Transcriptional regulator
CH92_RS04130	COG2814	Major facilitator Superfamily
CH92_RS04145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CH92_RS04175	COG1228	amidohydrolase
CH92_RS04220	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH92_RS04225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH92_RS04250	COG1063	alcohol dehydrogenase
CH92_RS04275	COG3938	Belongs to the proline racemase family
CH92_RS04280	COG2423	ornithine cyclodeaminase activity
CH92_RS04295	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_RS04295	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CH92_RS04300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH92_RS04305	COG1012	belongs to the aldehyde dehydrogenase family
CH92_RS04315	COG0028	Belongs to the TPP enzyme family
CH92_RS04320	COG2271	Major facilitator Superfamily
CH92_RS04325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH92_RS04340	COG0251	oxidation-reduction process
CH92_RS04355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH92_RS04360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH92_RS04365	COG1012	belongs to the aldehyde dehydrogenase family
CH92_RS04370	COG0247	lactate metabolic process
CH92_RS04370	COG0277	FAD linked oxidase domain protein
CH92_RS04375	COG0583	DNA-binding transcription factor activity
CH92_RS04395	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CH92_RS04400	COG0583	DNA-binding transcription factor activity
CH92_RS04405	COG2223	nitrite transmembrane transporter activity
CH92_RS04410	COG1960	acyl-CoA dehydrogenase activity
CH92_RS04415	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_RS04420	COG3038	cytochrome b561
CH92_RS04440	COG1620	l-lactate permease
CH92_RS04450	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CH92_RS04460	COG2914	Belongs to the UPF0125 (RnfH) family
CH92_RS04465	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH92_RS04475	COG0497	DNA recombination
CH92_RS04480	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CH92_RS04485	COG0443	Heat shock 70 kDa protein
CH92_RS04490	COG0484	heat shock protein binding
CH92_RS04495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CH92_RS04500	COG0505	Belongs to the CarA family
CH92_RS04525	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CH92_RS04535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH92_RS04540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CH92_RS04545	COG0149	triose-phosphate isomerase activity
CH92_RS04550	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH92_RS04565	COG0779	Required for maturation of 30S ribosomal subunits
CH92_RS04570	COG0195	Participates in both transcription termination and antitermination
CH92_RS04575	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CH92_RS04580	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CH92_RS04585	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CH92_RS04590	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CH92_RS04595	COG1185	polyribonucleotide nucleotidyltransferase activity
CH92_RS04600	COG2823	Periplasmic or secreted lipoprotein
CH92_RS04630	COG0166	Belongs to the GPI family
CH92_RS04635	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CH92_RS04640	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CH92_RS04645	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CH92_RS04665	COG4191	Histidine kinase
CH92_RS04675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH92_RS04680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH92_RS04685	COG0436	Aminotransferase
CH92_RS04700	COG1285	pathogenesis
CH92_RS04720	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS04725	COG0659	secondary active sulfate transmembrane transporter activity
CH92_RS04780	COG0501	Belongs to the peptidase M48B family
CH92_RS04790	COG2119	membrane
CH92_RS04795	COG2813	Specifically methylates the guanine in position
CH92_RS04800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH92_RS04805	COG1280	lysine exporter protein (LysE YggA)
CH92_RS04810	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_RS04815	COG4191	Histidine kinase
CH92_RS04815	COG0784	Response regulator, receiver
CH92_RS04820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH92_RS04825	COG2885	chlorophyll binding
CH92_RS04830	COG2205	protein histidine kinase activity
CH92_RS04830	COG3437	response regulator, receiver
CH92_RS04830	COG3850	Histidine kinase
CH92_RS04830	COG4999	Histidine kinase
CH92_RS04840	COG0204	Acyl-transferase
CH92_RS04850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CH92_RS04860	COG0386	Belongs to the glutathione peroxidase family
CH92_RS04865	COG1309	transcriptional regulator
CH92_RS04875	COG0655	NAD(P)H dehydrogenase (quinone) activity
CH92_RS04880	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CH92_RS04900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH92_RS04945	COG0693	protein deglycase activity
CH92_RS04950	COG4628	conserved protein (DUF2132)
CH92_RS04995	COG0714	Associated with various cellular activities
CH92_RS05020	COG2925	Exonuclease
CH92_RS05030	COG0788	formyltetrahydrofolate deformylase activity
CH92_RS05040	COG0433	COG0433 Predicted ATPase
CH92_RS05055	COG3022	response to hydroperoxide
CH92_RS05065	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CH92_RS05070	COG0315	cyclic pyranopterin monophosphate synthase activity
CH92_RS05075	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH92_RS05090	COG3706	GGDEF domain
CH92_RS05095	COG0400	carboxylic ester hydrolase activity
CH92_RS05100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH92_RS05105	COG4597	amino acid ABC transporter
CH92_RS05110	COG0765	amino acid transport
CH92_RS05115	COG1126	abc transporter atp-binding protein
CH92_RS05120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CH92_RS05120	COG0047	phosphoribosylformylglycinamidine synthase activity
CH92_RS05130	COG1764	response to oxidative stress
CH92_RS05135	COG1846	Transcriptional regulator
CH92_RS05140	COG3034	peptidoglycan biosynthetic process
CH92_RS05165	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CH92_RS05170	COG4536	flavin adenine dinucleotide binding
CH92_RS05175	COG4137	Cytochrome C assembly protein
CH92_RS05180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH92_RS05185	COG0228	four-way junction DNA binding
CH92_RS05190	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CH92_RS05195	COG0336	Belongs to the RNA methyltransferase TrmD family
CH92_RS05200	COG0335	large ribosomal subunit rRNA binding
CH92_RS05210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH92_RS05215	COG3791	Glutathione-dependent formaldehyde-activating
CH92_RS05230	COG1802	Transcriptional regulator
CH92_RS05240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_RS05250	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_RS05250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CH92_RS05255	COG1024	Enoyl-CoA hydratase
CH92_RS05265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH92_RS05270	COG0247	lactate metabolic process
CH92_RS05270	COG0277	FAD linked oxidase domain protein
CH92_RS05275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH92_RS05280	COG0418	dihydroorotase activity
CH92_RS05290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH92_RS05290	COG3008	intermembrane lipid transfer
CH92_RS05295	COG2995	paraquat-inducible protein a
CH92_RS05300	COG2995	paraquat-inducible protein a
CH92_RS05310	COG0137	argininosuccinate synthase activity
CH92_RS05315	COG0346	lactoylglutathione lyase activity
CH92_RS05325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH92_RS05335	COG4659	FMN binding
CH92_RS05340	COG4658	electron transport chain
CH92_RS05350	COG2878	Part of a membrane complex involved in electron transport
CH92_RS05355	COG4657	Part of a membrane complex involved in electron transport
CH92_RS05365	COG1024	Enoyl-CoA hydratase
CH92_RS05375	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CH92_RS05390	COG0354	folic acid binding
CH92_RS05395	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CH92_RS05425	COG3086	response to oxidative stress
CH92_RS05430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH92_RS05435	COG0481	GTPase activity
CH92_RS05450	COG0571	ribonuclease III activity
CH92_RS05460	COG1381	Involved in DNA repair and RecF pathway recombination
CH92_RS05465	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH92_RS05475	COG0583	DNA-binding transcription factor activity
CH92_RS05485	COG0500	methyltransferase
CH92_RS05490	COG2226	methyltransferase
CH92_RS05500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH92_RS05515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH92_RS05525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH92_RS05565	COG2856	Zn peptidase
CH92_RS05580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH92_RS05580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH92_RS05585	COG0489	protein tyrosine kinase activity
CH92_RS05590	COG1278	Cold shock
CH92_RS05595	COG0717	Belongs to the dCTP deaminase family
CH92_RS05610	COG0583	DNA-binding transcription factor activity
CH92_RS05630	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CH92_RS05645	COG1017	nitric oxide dioxygenase activity
CH92_RS05645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH92_RS05660	COG0469	pyruvate kinase activity
CH92_RS05670	COG2084	Dehydrogenase
CH92_RS05675	COG3622	Belongs to the hyi family
CH92_RS05680	COG3960	tartronate-semialdehyde synthase activity
CH92_RS05685	COG0583	DNA-binding transcription factor activity
CH92_RS05690	COG2351	hydroxyisourate hydrolase activity
CH92_RS05710	COG0708	Exodeoxyribonuclease III
CH92_RS05715	COG3287	FIST C domain
CH92_RS05715	COG2200	EAL domain
CH92_RS05715	COG2199	diguanylate cyclase activity
CH92_RS05750	COG2207	Transcriptional regulator
CH92_RS05755	COG1944	ATP diphosphatase activity
CH92_RS05770	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CH92_RS05795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH92_RS05805	COG0784	Response regulator, receiver
CH92_RS05805	COG4191	Histidine kinase
CH92_RS05840	COG1280	lysine exporter protein (LysE YggA)
CH92_RS05850	COG0656	L-ascorbic acid biosynthetic process
CH92_RS05855	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS05885	COG2133	pyrroloquinoline quinone binding
CH92_RS05890	COG4993	Dehydrogenase
CH92_RS05895	COG2996	Protein conserved in bacteria
CH92_RS05915	COG0489	protein tyrosine kinase activity
CH92_RS05940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH92_RS05965	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CH92_RS05985	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CH92_RS06035	COG1295	ribonuclease BN
CH92_RS06060	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CH92_RS06065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CH92_RS06075	COG1546	Belongs to the CinA family
CH92_RS06080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CH92_RS06085	COG2137	regulation of response to DNA damage stimulus
CH92_RS06105	COG3148	PFAM DTW domain containing protein
CH92_RS06110	COG0697	spore germination
CH92_RS06120	COG0583	DNA-binding transcription factor activity
CH92_RS06130	COG3012	SEC-C Motif Domain Protein
CH92_RS06150	COG1199	ATP-dependent helicase activity
CH92_RS06165	COG0259	pyridoxamine-phosphate oxidase activity
CH92_RS06175	COG3133	Outer membrane lipoprotein
CH92_RS06180	COG2111	Na H antiporter
CH92_RS06180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH92_RS06185	COG1006	Multisubunit Na H antiporter MnhC subunit
CH92_RS06190	COG0651	ATP synthesis coupled electron transport
CH92_RS06200	COG2212	antiporter activity
CH92_RS06205	COG1320	monovalent cation:proton antiporter activity
CH92_RS06210	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CH92_RS06215	COG0024	Methionine aminopeptidase
CH92_RS06220	COG0052	Belongs to the universal ribosomal protein uS2 family
CH92_RS06225	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CH92_RS06230	COG0528	UMP kinase activity
CH92_RS06235	COG0233	cytoplasmic translational termination
CH92_RS06240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CH92_RS06250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CH92_RS06260	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH92_RS06275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH92_RS06280	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH92_RS06285	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH92_RS06290	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CH92_RS06300	COG0825	malonyl-CoA metabolic process
CH92_RS06305	COG0037	tRNA processing
CH92_RS06310	COG0504	CTP synthase activity
CH92_RS06315	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CH92_RS06320	COG0148	phosphopyruvate hydratase activity
CH92_RS06345	COG0583	DNA-binding transcription factor activity
CH92_RS06350	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CH92_RS06360	COG1902	pentaerythritol trinitrate reductase activity
CH92_RS06365	COG0640	Transcriptional regulator
CH92_RS06370	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CH92_RS06375	COG0585	pseudouridine synthase activity
CH92_RS06380	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CH92_RS06385	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CH92_RS06425	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH92_RS06445	COG0217	transcriptional regulatory protein
CH92_RS06450	COG0697	spore germination
CH92_RS06460	COG0840	transmembrane signaling receptor activity
CH92_RS06470	COG0004	ammonium transporteR
CH92_RS06485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH92_RS06490	COG1309	transcriptional regulator
CH92_RS06495	COG0625	glutathione transferase activity
CH92_RS06520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH92_RS06525	COG0348	domain, Protein
CH92_RS06535	COG1380	Effector of murein hydrolase LrgA
CH92_RS06540	COG1346	cytolysis
CH92_RS06545	COG0596	Alpha beta hydrolase
CH92_RS06550	COG0655	NAD(P)H dehydrogenase (quinone) activity
CH92_RS06560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CH92_RS06565	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH92_RS06580	COG1805	sodium ion transport
CH92_RS06595	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH92_RS06605	COG1477	protein flavinylation
CH92_RS06615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH92_RS06620	COG0584	glycerophosphoryl diester phosphodiesterase
CH92_RS06635	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH92_RS06640	COG1136	(ABC) transporter
CH92_RS06645	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH92_RS06655	COG2333	competence protein COMEC
CH92_RS06655	COG0658	competence protein
CH92_RS06660	COG0811	peptide transport
CH92_RS06670	COG1663	tetraacyldisaccharide 4'-kinase activity
CH92_RS06675	COG2835	tetraacyldisaccharide 4'-kinase activity
CH92_RS06680	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CH92_RS06685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CH92_RS06690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CH92_RS06705	COG1530	ribonuclease E activity
CH92_RS06715	COG0546	phosphoglycolate phosphatase activity
CH92_RS06720	COG0616	signal peptide processing
CH92_RS06720	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CH92_RS06725	COG0424	maF-like protein
CH92_RS06735	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH92_RS06740	COG0416	fatty acid biosynthetic process
CH92_RS06755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH92_RS06760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH92_RS06770	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH92_RS06775	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CH92_RS06790	COG0084	hydrolase, TatD family'
CH92_RS06795	COG1113	amino acid transport
CH92_RS06825	COG2226	methyltransferase
CH92_RS06830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CH92_RS06835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH92_RS06840	COG2166	iron-sulfur cluster assembly
CH92_RS06845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH92_RS06850	COG2171	N-acyltransferase activity
CH92_RS06855	COG1393	Belongs to the ArsC family
CH92_RS06870	COG0436	Aminotransferase
CH92_RS06885	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH92_RS06890	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CH92_RS06900	COG0628	permease
CH92_RS06920	COG1393	Belongs to the ArsC family
CH92_RS06925	COG1295	ribonuclease BN
CH92_RS06930	COG3118	belongs to the thioredoxin family
CH92_RS06945	COG0442	prolyl-tRNA aminoacylation
CH92_RS06960	COG2900	Belongs to the SlyX family
CH92_RS06970	COG0783	Belongs to the Dps family
CH92_RS06975	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CH92_RS06985	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CH92_RS06990	COG0632	four-way junction helicase activity
CH92_RS06995	COG2255	four-way junction helicase activity
CH92_RS07000	COG0824	Thioesterase
CH92_RS07020	COG0823	Involved in the tonB-independent uptake of proteins
CH92_RS07025	COG2885	chlorophyll binding
CH92_RS07030	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH92_RS07040	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CH92_RS07050	COG0427	acetyl-CoA hydrolase
CH92_RS07065	COG0425	Belongs to the sulfur carrier protein TusA family
CH92_RS07075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH92_RS07085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH92_RS07095	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CH92_RS07125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH92_RS07135	COG2199	diguanylate cyclase activity
CH92_RS07150	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CH92_RS07220	COG2205	protein histidine kinase activity
CH92_RS07250	COG4580	involved in the transport of maltose and maltodextrins
CH92_RS07260	COG0583	DNA-binding transcription factor activity
CH92_RS07265	COG3485	protocatechuate 3,4-dioxygenase
CH92_RS07270	COG3485	protocatechuate 3,4-dioxygenase
CH92_RS07275	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH92_RS07280	COG0679	Auxin Efflux Carrier
CH92_RS07290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH92_RS07300	COG0366	Alpha amylase catalytic
CH92_RS07310	COG1175	transmembrane transport
CH92_RS07315	COG3833	ABC-type maltose transport systems, permease component
CH92_RS07320	COG2909	trisaccharide binding
CH92_RS07335	COG0366	Alpha amylase catalytic
CH92_RS07345	COG2076	Multidrug Resistance protein
CH92_RS07350	COG0385	Bile acid
CH92_RS07355	COG2974	May be involved in recombination
CH92_RS07370	COG0545	Peptidyl-prolyl cis-trans isomerase
CH92_RS07390	COG0556	nucleotide-excision repair
CH92_RS07405	COG0583	DNA-binding transcription factor activity
CH92_RS07410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH92_RS07450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CH92_RS07470	COG2814	Major facilitator Superfamily
CH92_RS07475	COG3091	SprT-like family
CH92_RS07495	COG0037	tRNA processing
CH92_RS07500	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH92_RS07505	COG2818	Glycosylase
CH92_RS07515	COG0791	NLP P60 protein
CH92_RS07520	COG0791	NLP P60 protein
CH92_RS07530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH92_RS07540	COG4206	TonB-dependent receptor
CH92_RS07555	COG1797	cobyrinic acid a,c-diamide synthase activity
CH92_RS07560	COG0778	Nitroreductase
CH92_RS07565	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CH92_RS07575	COG1492	cobalamin metabolic process
CH92_RS07585	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CH92_RS07590	COG0406	alpha-ribazole phosphatase activity
CH92_RS07595	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CH92_RS07625	COG2067	long-chain fatty acid transport protein
CH92_RS07640	COG3100	YcgL domain-containing protein
CH92_RS07645	COG2983	Belongs to the UPF0260 family
CH92_RS07655	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH92_RS07660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CH92_RS07665	COG0527	aspartate kinase activity
CH92_RS07670	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH92_RS07695	COG2239	Acts as a magnesium transporter
CH92_RS07700	COG3630	sodium ion export across plasma membrane
CH92_RS07705	COG5016	pyruvate
CH92_RS07705	COG0511	ligase activity, forming carbon-carbon bonds
CH92_RS07710	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CH92_RS07735	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CH92_RS07755	COG0835	chemotaxis
CH92_RS07755	COG0784	Response regulator, receiver
CH92_RS07760	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH92_RS07765	COG1815	bacterial-type flagellum-dependent cell motility
CH92_RS07780	COG1749	Flagellar hook protein flgE
CH92_RS07785	COG4787	bacterial-type flagellum-dependent cell motility
CH92_RS07795	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CH92_RS07800	COG1706	bacterial-type flagellum-dependent cell motility
CH92_RS07810	COG1256	bacterial-type flagellum assembly
CH92_RS07820	COG1555	photosystem II stabilization
CH92_RS07845	COG2200	EAL domain
CH92_RS07855	COG1362	aminopeptidase activity
CH92_RS07860	COG0564	pseudouridine synthase activity
CH92_RS07865	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH92_RS07870	COG2894	cell division
CH92_RS07875	COG0850	regulation of cytokinetic process
CH92_RS07880	COG1560	Kdo2-lipid A biosynthetic process
CH92_RS07890	COG2853	Lipoprotein
CH92_RS07905	COG3162	membrane
CH92_RS07910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH92_RS07940	COG3089	Belongs to the UPF0270 family
CH92_RS07950	COG1363	Peptidase, m42
CH92_RS07955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH92_RS07955	COG0189	ligase activity
CH92_RS07960	COG0367	asparagine synthase
CH92_RS07965	COG0583	DNA-binding transcription factor activity
CH92_RS07975	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CH92_RS07975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH92_RS07985	COG0183	Belongs to the thiolase family
CH92_RS07990	COG0114	fumarate hydratase activity
CH92_RS08000	COG0271	Belongs to the BolA IbaG family
CH92_RS08005	COG1054	Belongs to the UPF0176 family
CH92_RS08020	COG0840	transmembrane signaling receptor activity
CH92_RS08045	COG0583	DNA-binding transcription factor activity
CH92_RS08050	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CH92_RS08055	COG1960	acyl-CoA dehydrogenase activity
CH92_RS08065	COG2079	MmgE PrpD family protein
CH92_RS08075	COG2301	Belongs to the HpcH HpaI aldolase family
CH92_RS08095	COG1131	(ABC) transporter
CH92_RS08100	COG0842	Transport permease protein
CH92_RS08115	COG2853	Lipoprotein
CH92_RS08125	COG0745	RESPONSE REGULATOR receiver
CH92_RS08135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH92_RS08140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH92_RS08155	COG3181	Tripartite tricarboxylate transporter family receptor
CH92_RS08160	COG0028	Belongs to the TPP enzyme family
CH92_RS08165	COG0583	DNA-binding transcription factor activity
CH92_RS08170	COG0596	Alpha beta hydrolase
CH92_RS08180	COG0587	DNA-directed DNA polymerase activity
CH92_RS08200	COG0450	alkyl hydroperoxide reductase
CH92_RS08205	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CH92_RS08215	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CH92_RS08220	COG0077	Prephenate dehydratase
CH92_RS08220	COG1605	Chorismate mutase
CH92_RS08230	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CH92_RS08235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CH92_RS08250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH92_RS08255	COG0625	glutathione transferase activity
CH92_RS08260	COG0302	gtp cyclohydrolase
CH92_RS08265	COG2840	Smr protein MutS2
CH92_RS08295	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CH92_RS08305	COG0235	Class ii aldolase
CH92_RS08310	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CH92_RS08315	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CH92_RS08335	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH92_RS08340	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CH92_RS08350	COG0583	DNA-binding transcription factor activity
CH92_RS08365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH92_RS08375	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CH92_RS08380	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CH92_RS08395	COG0573	inorganic phosphate transmembrane transporter activity
CH92_RS08410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CH92_RS08415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH92_RS08425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH92_RS08450	COG0348	domain, Protein
CH92_RS08455	COG2010	Cytochrome c
CH92_RS08470	COG3278	Belongs to the heme-copper respiratory oxidase family
CH92_RS08475	COG2010	Cytochrome c
CH92_RS08485	COG3278	Belongs to the heme-copper respiratory oxidase family
CH92_RS08495	COG0840	transmembrane signaling receptor activity
CH92_RS08505	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CH92_RS08520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH92_RS08525	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH92_RS08525	COG2010	Cytochrome c
CH92_RS08535	COG1981	membrane
CH92_RS08540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH92_RS08545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH92_RS08555	COG3115	cell septum assembly
CH92_RS08560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CH92_RS08575	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CH92_RS08615	COG2009	succinate dehydrogenase
CH92_RS08620	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH92_RS08625	COG1053	succinate dehydrogenase
CH92_RS08630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH92_RS08650	COG0045	succinate-CoA ligase (ADP-forming) activity
CH92_RS08700	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CH92_RS08710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH92_RS08715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CH92_RS08750	COG0628	permease
CH92_RS08760	COG0709	Synthesizes selenophosphate from selenide and ATP
CH92_RS08765	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CH92_RS08775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH92_RS08780	COG0714	Associated with various cellular activities
CH92_RS08805	COG0084	hydrolase, TatD family'
CH92_RS08810	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CH92_RS08830	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH92_RS08835	COG4181	ATPase activity
CH92_RS08865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH92_RS08870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH92_RS08885	COG0560	Phosphoserine phosphatase
CH92_RS08910	COG1802	Transcriptional regulator
CH92_RS08920	COG0372	Belongs to the citrate synthase family
CH92_RS08935	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CH92_RS08945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH92_RS08960	COG0668	transmembrane transport
CH92_RS08990	COG2153	protein acetylation
CH92_RS08995	COG2850	peptidyl-arginine hydroxylation
CH92_RS09005	COG2915	High frequency lysogenization protein hflD homolog
CH92_RS09010	COG0482	sulfurtransferase activity
CH92_RS09035	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CH92_RS09040	COG0542	response to heat
CH92_RS09045	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH92_RS09050	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CH92_RS09055	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CH92_RS09060	COG0492	ferredoxin-NADP+ reductase activity
CH92_RS09070	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CH92_RS09075	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH92_RS09080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH92_RS09085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CH92_RS09090	COG1648	precorrin-2 dehydrogenase activity
CH92_RS09090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CH92_RS09095	COG0435	Glutathione S-transferase
CH92_RS09100	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH92_RS09105	COG2920	part of a sulfur-relay system
CH92_RS09135	COG0697	spore germination
CH92_RS09155	COG0437	4 iron, 4 sulfur cluster binding
CH92_RS09195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH92_RS09200	COG1845	cytochrome c oxidase, subunit III
CH92_RS09215	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS09220	COG0723	plastoquinol--plastocyanin reductase activity
CH92_RS09225	COG2999	glutathione oxidoreductase activity
CH92_RS09245	COG3383	formate dehydrogenase (NAD+) activity
CH92_RS09265	COG1595	DNA-templated transcription, initiation
CH92_RS09275	COG3220	belongs to the UPF0276 family
CH92_RS09290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH92_RS09315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CH92_RS09320	COG0372	Belongs to the citrate synthase family
CH92_RS09350	COG0402	S-adenosylhomocysteine deaminase activity
CH92_RS09355	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS09365	COG1116	anion transmembrane transporter activity
CH92_RS09370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH92_RS09380	COG1802	Transcriptional regulator
CH92_RS09385	COG0154	amidase activity
CH92_RS09410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH92_RS09415	COG2995	paraquat-inducible protein a
CH92_RS09420	COG2995	paraquat-inducible protein a
CH92_RS09425	COG3008	intermembrane lipid transfer
CH92_RS09460	COG0697	spore germination
CH92_RS09465	COG3284	Transcriptional regulator
CH92_RS09470	COG1012	belongs to the aldehyde dehydrogenase family
CH92_RS09480	COG4772	TonB-dependent receptor
CH92_RS09495	COG0840	transmembrane signaling receptor activity
CH92_RS09520	COG3121	Chaperone
CH92_RS09535	COG0745	RESPONSE REGULATOR receiver
CH92_RS09545	COG2198	Histidine kinase
CH92_RS09545	COG0643	Histidine kinase
CH92_RS09550	COG0840	transmembrane signaling receptor activity
CH92_RS09555	COG0835	chemotaxis
CH92_RS09560	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH92_RS09565	COG2201	protein-glutamate methylesterase activity
CH92_RS09570	COG2197	response regulator
CH92_RS09575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH92_RS09585	COG3813	Protein conserved in bacteria
CH92_RS09590	COG2205	protein histidine kinase activity
CH92_RS09600	COG0784	Response regulator, receiver
CH92_RS09600	COG4191	Histidine kinase
CH92_RS09625	COG0183	Belongs to the thiolase family
CH92_RS09630	COG0784	Response regulator, receiver
CH92_RS09630	COG0835	chemotaxis
CH92_RS09640	COG0417	DNA replication proofreading
CH92_RS09675	COG2172	sigma factor antagonist activity
CH92_RS09680	COG1366	Belongs to the anti-sigma-factor antagonist family
CH92_RS09685	COG1366	Belongs to the anti-sigma-factor antagonist family
CH92_RS09695	COG4991	sh3 domain protein
CH92_RS09710	COG0515	serine threonine protein kinase
CH92_RS09710	COG2815	serine threonine protein kinase
CH92_RS09715	COG2116	formate transmembrane transporter activity
CH92_RS09725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH92_RS09725	COG2146	nitrite reductase [NAD(P)H] activity
CH92_RS09730	COG4989	oxidoreductase activity
CH92_RS09740	COG2130	NADP-dependent
CH92_RS09790	COG1757	Na H antiporter
CH92_RS09795	COG2423	ornithine cyclodeaminase activity
CH92_RS09810	COG1741	Belongs to the pirin family
CH92_RS09815	COG0583	DNA-binding transcription factor activity
CH92_RS09825	COG2814	Major facilitator Superfamily
CH92_RS09840	COG2223	nitrite transmembrane transporter activity
CH92_RS09845	COG2207	Transcriptional regulator
CH92_RS09855	COG2207	Transcriptional regulator
CH92_RS09870	COG3268	Saccharopine dehydrogenase
CH92_RS09875	COG1309	transcriptional regulator
CH92_RS09880	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS09900	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CH92_RS09910	COG1126	abc transporter atp-binding protein
CH92_RS09915	COG0765	amino acid transport
CH92_RS09920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH92_RS09950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH92_RS09955	COG0473	3-isopropylmalate dehydrogenase activity
CH92_RS09955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH92_RS09975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH92_RS09980	COG0583	DNA-binding transcription factor activity
CH92_RS10000	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH92_RS10000	COG1902	pentaerythritol trinitrate reductase activity
CH92_RS10005	COG2375	cellular response to nickel ion
CH92_RS10020	COG1335	isochorismatase
CH92_RS10045	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CH92_RS10060	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH92_RS10065	COG0625	glutathione transferase activity
CH92_RS10090	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CH92_RS10115	COG1696	Membrane protein involved in D-alanine export
CH92_RS10130	COG2031	fatty acid transporter
CH92_RS10145	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CH92_RS10150	COG0583	DNA-binding transcription factor activity
CH92_RS10160	COG0784	Response regulator, receiver
CH92_RS10160	COG4191	Histidine kinase
CH92_RS10165	COG1414	Transcriptional regulator
CH92_RS10170	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CH92_RS10175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CH92_RS10185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CH92_RS10190	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CH92_RS10195	COG0025	NhaP-type Na H and K H
CH92_RS10225	COG0583	DNA-binding transcription factor activity
CH92_RS10245	COG0251	oxidation-reduction process
CH92_RS10250	COG1609	Transcriptional regulator
CH92_RS10255	COG0673	inositol 2-dehydrogenase activity
CH92_RS10265	COG2211	Major facilitator Superfamily
CH92_RS10280	COG0024	Methionine aminopeptidase
CH92_RS10295	COG0596	Alpha beta hydrolase
CH92_RS10300	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS10320	COG4191	Histidine kinase
CH92_RS10325	COG0745	RESPONSE REGULATOR receiver
CH92_RS10330	COG4566	intracellular signal transduction
CH92_RS10335	COG0583	DNA-binding transcription factor activity
CH92_RS10345	COG2814	Major facilitator Superfamily
CH92_RS10350	COG1335	isochorismatase
CH92_RS10365	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CH92_RS10370	COG3224	Antibiotic biosynthesis monooxygenase
CH92_RS10385	COG1335	isochorismatase
CH92_RS10400	COG1017	nitric oxide dioxygenase activity
CH92_RS10400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH92_RS10405	COG0625	glutathione transferase activity
CH92_RS10420	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS10430	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_RS10440	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CH92_RS10450	COG0789	Transcriptional regulator
CH92_RS10485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CH92_RS10490	COG1960	acyl-CoA dehydrogenase activity
CH92_RS10495	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_RS10535	COG1024	Enoyl-CoA hydratase
CH92_RS10560	COG1960	acyl-CoA dehydrogenase activity
CH92_RS10565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH92_RS10570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CH92_RS10575	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_RS10580	COG1960	acyl-CoA dehydrogenase activity
CH92_RS10585	COG1024	Enoyl-CoA hydratase
CH92_RS10615	COG4221	oxidoreductase activity
CH92_RS10645	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CH92_RS10660	COG4294	response to UV
CH92_RS10665	COG0210	DNA helicase
CH92_RS10670	COG0625	glutathione transferase activity
CH92_RS10675	COG0583	DNA-binding transcription factor activity
CH92_RS10690	COG1802	Transcriptional regulator
CH92_RS10700	COG0765	amino acid transport
CH92_RS10705	COG0765	amino acid transport
CH92_RS10710	COG1126	abc transporter atp-binding protein
CH92_RS10720	COG0415	Belongs to the DNA photolyase family
CH92_RS10725	COG3272	Protein of unknown function (DUF1722)
CH92_RS10730	COG1090	epimerase
CH92_RS10735	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CH92_RS10745	COG1366	Belongs to the anti-sigma-factor antagonist family
CH92_RS10750	COG0789	Transcriptional regulator
CH92_RS10755	COG1025	Belongs to the peptidase M16 family
CH92_RS10780	COG2323	membrane
CH92_RS10795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH92_RS10800	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
CH92_RS10810	COG0535	radical SAM domain protein
CH92_RS10825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CH92_RS10830	COG1742	UPF0060 membrane protein
CH92_RS10835	COG0431	NADPH-dependent FMN reductase
CH92_RS10840	COG0640	Transcriptional regulator
CH92_RS10845	COG0798	PFAM Bile acid sodium symporter
CH92_RS10855	COG0322	excinuclease ABC activity
CH92_RS10920	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_RS10930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH92_RS10960	COG3181	Tripartite tricarboxylate transporter family receptor
CH92_RS10970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH92_RS10975	COG1012	belongs to the aldehyde dehydrogenase family
CH92_RS10985	COG2721	sulfolactate sulfo-lyase activity
CH92_RS10990	COG0277	FAD linked oxidase domain protein
CH92_RS10995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH92_RS11005	COG0277	FAD linked oxidase domain protein
CH92_RS11050	COG2847	Copper chaperone PCu(A)C
CH92_RS11055	COG2149	membrane
CH92_RS11105	COG0583	DNA-binding transcription factor activity
CH92_RS11130	COG3685	Protein conserved in bacteria
CH92_RS11135	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CH92_RS11135	COG3264	Mechanosensitive ion channel
CH92_RS11140	COG1058	Belongs to the CinA family
CH92_RS11140	COG1546	Belongs to the CinA family
CH92_RS11145	COG0297	glycogen (starch) synthase activity
CH92_RS11150	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CH92_RS11155	COG1640	4-alpha-glucanotransferase
CH92_RS11185	COG3384	dioxygenase
CH92_RS11190	COG0583	DNA-binding transcription factor activity
CH92_RS11205	COG3568	Endonuclease Exonuclease Phosphatase
CH92_RS11210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH92_RS11215	COG0392	lysyltransferase activity
CH92_RS11220	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CH92_RS11225	COG0366	Alpha amylase catalytic
CH92_RS11240	COG2864	formate dehydrogenase
CH92_RS11245	COG0437	4 iron, 4 sulfur cluster binding
CH92_RS11265	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CH92_RS11270	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS11310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH92_RS11330	COG0728	peptidoglycan biosynthetic process
CH92_RS11335	COG5642	Protein of unknown function (DUF2384)
CH92_RS11365	COG1024	Enoyl-CoA hydratase
CH92_RS11365	COG1250	3-hydroxyacyl-CoA dehydrogenase
CH92_RS11380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_RS11385	COG2358	TRAP transporter, solute receptor (TAXI family
CH92_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS11400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_RS11410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_RS11420	COG1012	belongs to the aldehyde dehydrogenase family
CH92_RS11425	COG0583	DNA-binding transcription factor activity
CH92_RS11430	COG0163	prenyltransferase activity
CH92_RS11460	COG2199	diguanylate cyclase activity
CH92_RS11460	COG2203	Gaf domain
CH92_RS11480	COG0784	Response regulator, receiver
CH92_RS11480	COG5002	protein histidine kinase activity
CH92_RS11505	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS11540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CH92_RS11555	COG0395	ABC-type sugar transport system, permease component
CH92_RS11565	COG3842	ATPase activity
CH92_RS11575	COG3284	Transcriptional regulator
CH92_RS11580	COG0215	cysteine-tRNA ligase activity
CH92_RS11585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH92_RS11590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH92_RS11595	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH92_RS11620	COG0488	(ABC) transporter
CH92_RS11625	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CH92_RS11635	COG1278	Cold shock
CH92_RS11640	COG1968	undecaprenyl-diphosphatase activity
CH92_RS11645	COG0840	transmembrane signaling receptor activity
CH92_RS11665	COG2323	membrane
CH92_RS11675	COG3706	GGDEF domain
CH92_RS11680	COG0745	RESPONSE REGULATOR receiver
CH92_RS11685	COG0316	Belongs to the HesB IscA family
CH92_RS11685	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CH92_RS11695	COG5001	Diguanylate cyclase
CH92_RS11705	COG0697	spore germination
CH92_RS11720	COG2223	nitrite transmembrane transporter activity
CH92_RS11725	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CH92_RS11730	COG0515	serine threonine protein kinase
CH92_RS11730	COG2815	serine threonine protein kinase
CH92_RS11755	COG0604	alcohol dehydrogenase
CH92_RS11760	COG0616	signal peptide processing
CH92_RS11780	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS11805	COG2816	NAD+ diphosphatase activity
CH92_RS11815	COG1024	Enoyl-CoA hydratase
CH92_RS11825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH92_RS11830	COG0328	RNA-DNA hybrid ribonuclease activity
CH92_RS11845	COG1388	LysM domain
CH92_RS11845	COG0741	lytic transglycosylase activity
CH92_RS11855	COG4166	transmembrane transport
CH92_RS11865	COG4174	ABC transporter (Permease)
CH92_RS11870	COG4239	(ABC) transporter, permease
CH92_RS11875	COG4172	Belongs to the ABC transporter superfamily
CH92_RS11885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH92_RS11895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH92_RS11900	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CH92_RS11910	COG0544	peptidyl-prolyl cis-trans isomerase activity
CH92_RS11915	COG2259	Doxx family
CH92_RS11925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_RS11935	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_RS11950	COG1115	amino acid carrier protein
CH92_RS11955	COG2911	Protein conserved in bacteria
CH92_RS11960	COG0729	surface antigen
CH92_RS11995	COG1175	transmembrane transport
CH92_RS12015	COG1070	Carbohydrate kinase
CH92_RS12030	COG1609	Transcriptional regulator
CH92_RS12035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_RS12040	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_RS12045	COG3265	gluconokinase activity
CH92_RS12050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH92_RS12055	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH92_RS12070	COG2056	Na+-H+ antiporter family
CH92_RS12075	COG0720	synthase
CH92_RS12115	COG0402	S-adenosylhomocysteine deaminase activity
CH92_RS12120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH92_RS12125	COG0546	phosphoglycolate phosphatase activity
CH92_RS12130	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS12155	COG0800	Aldolase
CH92_RS12170	COG1737	Transcriptional regulator
CH92_RS12185	COG3842	ATPase activity
CH92_RS12190	COG0395	ABC-type sugar transport system, permease component
CH92_RS12195	COG1175	transmembrane transport
CH92_RS12200	COG1653	transport
CH92_RS12240	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CH92_RS12250	COG0180	Tryptophanyl-tRNA synthetase
CH92_RS12255	COG0009	L-threonylcarbamoyladenylate synthase
CH92_RS12260	COG0613	PHP domain protein
CH92_RS12265	COG2917	probably involved in intracellular septation
CH92_RS12270	COG2350	Protein conserved in bacteria
CH92_RS12280	COG0745	RESPONSE REGULATOR receiver
CH92_RS12295	COG0778	Nitroreductase
CH92_RS12300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH92_RS12305	COG0590	tRNA wobble adenosine to inosine editing
CH92_RS12310	COG2354	Protein conserved in bacteria
CH92_RS12325	COG2207	Transcriptional regulator
CH92_RS12350	COG1012	belongs to the aldehyde dehydrogenase family
CH92_RS12370	COG1752	Esterase of the alpha-beta hydrolase superfamily
CH92_RS12380	COG1846	Transcriptional regulator
CH92_RS12385	COG0514	ATP-dependent DNA helicase (RecQ)
CH92_RS12395	COG2832	Protein of unknown function (DUF454)
CH92_RS12410	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CH92_RS12425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CH92_RS12455	COG0121	glutamine amidotransferase
CH92_RS12465	COG0589	response to stress
CH92_RS12475	COG0488	(ABC) transporter
CH92_RS12480	COG0741	lytic transglycosylase activity
CH92_RS12485	COG0633	Ferredoxin
CH92_RS12485	COG3217	Mosc domain protein beta barrel domain protein
CH92_RS12505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CH92_RS12535	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH92_RS12555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_RS12605	COG2003	Belongs to the UPF0758 family
CH92_RS12635	COG1201	RNA secondary structure unwinding
CH92_RS12660	COG0515	serine threonine protein kinase
CH92_RS12675	COG0776	regulation of translation
CH92_RS12680	COG0072	phenylalanine-tRNA ligase activity
CH92_RS12685	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CH92_RS12690	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CH92_RS12695	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CH92_RS12700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CH92_RS12705	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CH92_RS12715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH92_RS12740	COG0303	'Molybdopterin
CH92_RS12745	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH92_RS12800	COG3171	Protein conserved in bacteria
CH92_RS12805	COG2027	D-alanyl-D-alanine carboxypeptidase
CH92_RS12810	COG0116	Belongs to the methyltransferase superfamily
CH92_RS12810	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CH92_RS12815	COG0167	dihydroorotate dehydrogenase activity
CH92_RS12835	COG0714	Associated with various cellular activities
CH92_RS12865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH92_RS12870	COG3707	response regulator
CH92_RS12875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH92_RS12875	COG1116	anion transmembrane transporter activity
CH92_RS12880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH92_RS12885	COG1116	anion transmembrane transporter activity
CH92_RS12905	COG2223	nitrite transmembrane transporter activity
CH92_RS12920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH92_RS12925	COG2146	nitrite reductase [NAD(P)H] activity
CH92_RS12930	COG0243	molybdopterin cofactor binding
CH92_RS12940	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH92_RS12945	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH92_RS12965	COG1034	ATP synthesis coupled electron transport
CH92_RS12970	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CH92_RS12975	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH92_RS12985	COG0713	ATP synthesis coupled electron transport
CH92_RS13000	COG1007	ATP synthesis coupled electron transport
CH92_RS13015	COG0308	aminopeptidase N
CH92_RS13035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CH92_RS13040	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH92_RS13075	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH92_RS13075	COG1902	pentaerythritol trinitrate reductase activity
CH92_RS13095	COG1294	oxidase, subunit
CH92_RS13100	COG1271	oxidase subunit
CH92_RS13130	COG1286	toxin biosynthetic process
CH92_RS13135	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH92_RS13140	COG0285	dihydrofolate synthase activity
CH92_RS13145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CH92_RS13150	COG0135	phosphoribosylanthranilate isomerase activity
CH92_RS13180	COG0066	3-isopropylmalate dehydratase activity
CH92_RS13185	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CH92_RS13205	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS13270	COG0438	transferase activity, transferring glycosyl groups
CH92_RS13315	COG0745	RESPONSE REGULATOR receiver
CH92_RS13320	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CH92_RS13330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CH92_RS13340	COG1309	transcriptional regulator
CH92_RS13370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH92_RS13380	COG4221	oxidoreductase activity
CH92_RS13390	COG3845	ABC transporter
CH92_RS13395	COG4603	Belongs to the binding-protein-dependent transport system permease family
CH92_RS13400	COG1079	Belongs to the binding-protein-dependent transport system permease family
CH92_RS13415	COG0387	Pfam Sodium calcium exchanger
CH92_RS13435	COG1012	belongs to the aldehyde dehydrogenase family
CH92_RS13440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH92_RS13490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CH92_RS13525	COG0183	Belongs to the thiolase family
CH92_RS13530	COG1024	Enoyl-CoA hydratase
CH92_RS13530	COG1250	3-hydroxyacyl-CoA dehydrogenase
CH92_RS13535	COG1770	oligopeptidase
CH92_RS13545	COG2988	succinylglutamate desuccinylase activity
CH92_RS13555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CH92_RS13575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH92_RS13580	COG0668	transmembrane transport
CH92_RS13585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CH92_RS13600	COG0583	DNA-binding transcription factor activity
CH92_RS13605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CH92_RS13610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CH92_RS13615	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
CH92_RS13630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH92_RS13645	COG0438	transferase activity, transferring glycosyl groups
CH92_RS13665	COG0463	Glycosyl transferase, family 2
CH92_RS13680	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH92_RS13685	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH92_RS13690	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CH92_RS13695	COG0776	regulation of translation
CH92_RS13710	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CH92_RS13715	COG0471	metal ion transport
CH92_RS13720	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CH92_RS13735	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CH92_RS13760	COG0625	glutathione transferase activity
CH92_RS13770	COG0386	Belongs to the glutathione peroxidase family
CH92_RS13775	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CH92_RS13780	COG0436	Aminotransferase
CH92_RS13790	COG0501	Belongs to the peptidase M48B family
CH92_RS13795	COG0500	methyltransferase
CH92_RS13840	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CH92_RS13870	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH92_RS13885	COG0835	chemotaxis
CH92_RS13895	COG1192	Involved in chromosome partitioning
CH92_RS13900	COG1360	Flagellar Motor Protein
CH92_RS13905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CH92_RS13910	COG2201	protein-glutamate methylesterase activity
CH92_RS13915	COG2198	Histidine kinase
CH92_RS13915	COG0784	Response regulator, receiver
CH92_RS13915	COG0643	Histidine kinase
CH92_RS13920	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH92_RS13950	COG2032	superoxide dismutase activity
CH92_RS13965	COG1987	bacterial-type flagellum assembly
CH92_RS13990	COG1580	Controls the rotational direction of flagella during chemotaxis
CH92_RS14005	COG0745	RESPONSE REGULATOR receiver
CH92_RS14040	COG1677	Flagellar hook-basal body complex protein FliE
CH92_RS14045	COG3135	benzoate transporter
CH92_RS14050	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS14055	COG2130	NADP-dependent
CH92_RS14065	COG3300	MHYT domain
CH92_RS14065	COG5001	Diguanylate cyclase
CH92_RS14075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH92_RS14110	COG1278	Cold shock
CH92_RS14130	COG2937	Belongs to the GPAT DAPAT family
CH92_RS14150	COG1272	protein, Hemolysin III
CH92_RS14185	COG2132	Multicopper oxidase
CH92_RS14205	COG2943	transferase activity, transferring hexosyl groups
CH92_RS14210	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CH92_RS14235	COG1793	dna ligase
CH92_RS14240	COG1201	RNA secondary structure unwinding
CH92_RS14270	COG3956	TIGRFAM MazG family protein
CH92_RS14275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH92_RS14280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CH92_RS14290	COG0405	Gamma-glutamyltransferase
CH92_RS14295	COG0784	Response regulator, receiver
CH92_RS14295	COG2205	protein histidine kinase activity
CH92_RS14295	COG5002	protein histidine kinase activity
CH92_RS14300	COG2860	membrane
CH92_RS14315	COG2205	protein histidine kinase activity
CH92_RS14320	COG0745	RESPONSE REGULATOR receiver
CH92_RS14325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CH92_RS14325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH92_RS14330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH92_RS14375	COG0697	spore germination
CH92_RS14380	COG0583	DNA-binding transcription factor activity
CH92_RS14385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CH92_RS14400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH92_RS14405	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CH92_RS14410	COG2226	methyltransferase
CH92_RS14435	COG1733	regulation of RNA biosynthetic process
CH92_RS14450	COG3300	MHYT domain
CH92_RS14450	COG5001	Diguanylate cyclase
CH92_RS14455	COG2188	Transcriptional regulator
CH92_RS14470	COG0840	transmembrane signaling receptor activity
CH92_RS14480	COG3192	ethanolamine utilization protein
CH92_RS14495	COG0492	ferredoxin-NADP+ reductase activity
CH92_RS14535	COG4771	TonB-dependent receptor
CH92_RS14555	COG3459	Glycosyltransferase 36 associated
CH92_RS14565	COG4774	siderophore transport
CH92_RS14570	COG0826	peptidase U32
CH92_RS14590	COG4774	siderophore transport
CH92_RS14595	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH92_RS14605	COG2814	Major facilitator Superfamily
CH92_RS14615	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS14630	COG1846	Transcriptional regulator
CH92_RS14640	COG1566	PFAM secretion protein HlyD family protein
CH92_RS14645	COG2814	Major facilitator Superfamily
CH92_RS14650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH92_RS14670	COG0069	glutamate synthase activity
CH92_RS14680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH92_RS14695	COG1283	sodium-dependent phosphate transmembrane transporter activity
CH92_RS14705	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH92_RS14715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH92_RS14735	COG0668	transmembrane transport
CH92_RS14745	COG0483	inositol monophosphate 1-phosphatase activity
CH92_RS14765	COG0742	ribosomal rna small subunit methyltransferase
CH92_RS14775	COG1801	Protein of unknown function DUF72
CH92_RS14785	COG1214	PFAM Peptidase M22, glycoprotease
CH92_RS14795	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CH92_RS14825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH92_RS14830	COG0235	Class ii aldolase
CH92_RS14835	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_RS14865	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CH92_RS14875	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_RS14885	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CH92_RS14900	COG1902	pentaerythritol trinitrate reductase activity
CH92_RS14905	COG3383	formate dehydrogenase (NAD+) activity
CH92_RS14910	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH92_RS14920	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CH92_RS14925	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CH92_RS14930	COG1984	allophanate hydrolase subunit 2
CH92_RS14935	COG1914	H( )-stimulated, divalent metal cation uptake system
CH92_RS14955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH92_RS14965	COG3842	ATPase activity
CH92_RS14985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CH92_RS14985	COG0519	Catalyzes the synthesis of GMP from XMP
CH92_RS15000	COG1570	exodeoxyribonuclease VII activity
CH92_RS15005	COG0741	lytic transglycosylase activity
CH92_RS15005	COG1196	nuclear chromosome segregation
CH92_RS15005	COG0739	heme binding
CH92_RS15015	COG0668	transmembrane transport
CH92_RS15020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CH92_RS15025	COG1064	alcohol dehydrogenase
CH92_RS15035	COG2356	endonuclease I
CH92_RS15040	COG3647	Membrane
CH92_RS15055	COG0436	Aminotransferase
CH92_RS15060	COG1160	GTP binding
CH92_RS15070	COG2976	Protein conserved in bacteria
CH92_RS15075	COG0124	histidyl-tRNA synthetase
CH92_RS15080	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CH92_RS15095	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CH92_RS15100	COG0105	UTP biosynthetic process
CH92_RS15115	COG0443	Heat shock 70 kDa protein
CH92_RS15120	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH92_RS15125	COG0316	Belongs to the HesB IscA family
CH92_RS15135	COG1104	cysteine desulfurase activity
CH92_RS15160	COG3134	Outer membrane lipoprotein
CH92_RS15175	COG1862	Preprotein translocase
CH92_RS15195	COG1278	Cold shock
CH92_RS15205	COG0795	lipopolysaccharide-transporting ATPase activity
CH92_RS15210	COG0795	lipopolysaccharide-transporting ATPase activity
CH92_RS15215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CH92_RS15245	COG0477	Major facilitator Superfamily
CH92_RS15250	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CH92_RS15270	COG3081	Nucleoid-associated protein
CH92_RS15275	COG1968	undecaprenyl-diphosphatase activity
CH92_RS15285	COG2827	Endonuclease containing a URI domain
CH92_RS15290	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CH92_RS15295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH92_RS15300	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CH92_RS15310	COG0583	DNA-binding transcription factor activity
CH92_RS15335	COG3530	Putative quorum-sensing-regulated virulence factor
CH92_RS15350	COG2814	Major facilitator Superfamily
CH92_RS15370	COG0784	Response regulator, receiver
CH92_RS15375	COG3920	Histidine kinase
CH92_RS15380	COG0471	metal ion transport
CH92_RS15380	COG0490	domain, Protein
CH92_RS15405	COG2733	membrane
CH92_RS15420	COG2610	gluconate transmembrane transporter activity
CH92_RS15425	COG0625	glutathione transferase activity
CH92_RS15460	COG1335	isochorismatase
CH92_RS15470	COG0730	response to heat
CH92_RS15475	COG1234	tRNA 3'-trailer cleavage
CH92_RS15485	COG0655	NAD(P)H dehydrogenase (quinone) activity
CH92_RS15495	COG1309	transcriptional regulator
CH92_RS15515	COG1643	Atp-dependent helicase
CH92_RS15525	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_RS15530	COG0318	PFAM AMP-dependent synthetase and ligase
CH92_RS15535	COG2030	dehydratase
CH92_RS15560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CH92_RS15565	COG1201	RNA secondary structure unwinding
CH92_RS15575	COG4221	oxidoreductase activity
CH92_RS15580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CH92_RS15590	COG1404	Belongs to the peptidase S8 family
CH92_RS15590	COG4935	Belongs to the peptidase S8 family
CH92_RS15610	COG0513	Belongs to the DEAD box helicase family
CH92_RS15640	COG0443	Heat shock 70 kDa protein
CH92_RS15645	COG2271	Major facilitator Superfamily
CH92_RS15650	COG3622	Belongs to the hyi family
CH92_RS15655	COG2084	Dehydrogenase
CH92_RS15675	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH92_RS15685	COG3639	organic phosphonate transmembrane transporter activity
CH92_RS15745	COG0402	S-adenosylhomocysteine deaminase activity
CH92_RS15750	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH92_RS15760	COG1121	(ABC) transporter
CH92_RS15765	COG1802	Transcriptional regulator
CH92_RS15770	COG2252	PERMEase
CH92_RS15795	COG4266	Belongs to the allantoicase family
CH92_RS15800	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CH92_RS15810	COG2233	PERMEase
CH92_RS15815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH92_RS15815	COG4651	solute:proton antiporter activity
CH92_RS15820	COG2233	PERMEase
CH92_RS15830	COG0840	transmembrane signaling receptor activity
CH92_RS15845	COG1309	transcriptional regulator
CH92_RS15870	COG1704	LemA family
CH92_RS15900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH92_RS15905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH92_RS15915	COG0459	protein refolding
CH92_RS15920	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CH92_RS15925	COG3030	protein affecting phage T7 exclusion by the F plasmid
CH92_RS15935	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS15945	COG3695	enzyme binding
CH92_RS15955	COG0668	transmembrane transport
CH92_RS15960	COG1666	GTP binding
CH92_RS15965	COG0745	RESPONSE REGULATOR receiver
CH92_RS15975	COG4191	Histidine kinase
CH92_RS15980	COG2096	Adenosyltransferase
CH92_RS16010	COG0494	nUDIX hydrolase
CH92_RS16020	COG0653	protein targeting
CH92_RS16060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH92_RS16065	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CH92_RS16085	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CH92_RS16090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH92_RS16100	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CH92_RS16105	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CH92_RS16115	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CH92_RS16120	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CH92_RS16140	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CH92_RS16160	COG1408	metallophosphoesterase
CH92_RS16170	COG0583	DNA-binding transcription factor activity
CH92_RS16175	COG2814	Major facilitator Superfamily
CH92_RS16180	COG0656	L-ascorbic acid biosynthetic process
CH92_RS16195	COG1196	nuclear chromosome segregation
CH92_RS16220	COG0165	Argininosuccinate lyase
CH92_RS16230	COG0583	DNA-binding transcription factor activity
CH92_RS16245	COG0288	reversible hydration of carbon dioxide
CH92_RS16250	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CH92_RS16255	COG1877	trehalose-phosphatase activity
CH92_RS16265	COG0456	acetyltransferase
CH92_RS16275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CH92_RS16320	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CH92_RS16330	COG1183	phosphatidylcholine synthase activity
CH92_RS16335	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CH92_RS16345	COG0028	Belongs to the TPP enzyme family
CH92_RS16355	COG3098	single-species biofilm formation
CH92_RS16365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH92_RS16375	COG2226	methyltransferase
CH92_RS16410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CH92_RS16425	COG2264	protein methyltransferase activity
CH92_RS16435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH92_RS16445	COG0138	bifunctional purine biosynthesis protein purh
CH92_RS16450	COG0151	Belongs to the GarS family
CH92_RS16455	COG2205	protein histidine kinase activity
CH92_RS16455	COG5002	protein histidine kinase activity
CH92_RS16455	COG0784	Response regulator, receiver
CH92_RS16460	COG2124	cytochrome p450
CH92_RS16475	COG0679	Auxin Efflux Carrier
CH92_RS16495	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CH92_RS16500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH92_RS16515	COG1181	Belongs to the D-alanine--D-alanine ligase family
CH92_RS16520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH92_RS16525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CH92_RS16530	COG0772	Belongs to the SEDS family
CH92_RS16535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CH92_RS16540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH92_RS16545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH92_RS16550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH92_RS16565	COG0275	rRNA processing
CH92_RS16580	COG3107	peptidoglycan biosynthetic process
CH92_RS16585	COG0792	nuclease activity
CH92_RS16590	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CH92_RS16595	COG2823	Periplasmic or secreted lipoprotein
CH92_RS16600	COG2969	positive regulation of protein catabolic process
CH92_RS16605	COG0625	glutathione transferase activity
CH92_RS16610	COG2857	Cytochrome c1
CH92_RS16615	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CH92_RS16620	COG0723	plastoquinol--plastocyanin reductase activity
CH92_RS16625	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CH92_RS16630	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CH92_RS16635	COG0667	Aldo Keto reductase
CH92_RS16650	COG0237	dephospho-CoA kinase activity
CH92_RS16655	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CH92_RS16675	COG1943	Transposase
CH92_RS16700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH92_RS16705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CH92_RS16710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CH92_RS16715	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CH92_RS16720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CH92_RS16745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH92_RS16750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH92_RS16755	COG1127	ABC transporter
CH92_RS16765	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH92_RS16775	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH92_RS16780	COG1137	ATPase activity
CH92_RS16785	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH92_RS16800	COG1660	Displays ATPase and GTPase activities
CH92_RS16810	COG0312	modulator of DNA gyrase
CH92_RS16820	COG0312	modulator of DNA gyrase
CH92_RS16825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH92_RS16835	COG1530	ribonuclease E activity
CH92_RS16840	COG0424	maF-like protein
CH92_RS16850	COG1792	Involved in formation and maintenance of cell shape
CH92_RS16855	COG1077	Cell shape determining protein MreB Mrl
CH92_RS16860	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CH92_RS16870	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CH92_RS16875	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH92_RS16880	COG0530	calcium, potassium:sodium antiporter activity
CH92_RS16900	COG0739	heme binding
CH92_RS16915	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CH92_RS16950	COG4774	siderophore transport
CH92_RS16955	COG3128	pkhd-type hydroxylase
CH92_RS16965	COG0019	diaminopimelate decarboxylase activity
CH92_RS16970	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CH92_RS16975	COG0564	pseudouridine synthase activity
CH92_RS16985	COG0028	Belongs to the TPP enzyme family
CH92_RS17005	COG3212	peptidase
CH92_RS17035	COG0420	3'-5' exonuclease activity
CH92_RS17060	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CH92_RS17085	COG1607	acyl-coa hydrolase
CH92_RS17090	COG2824	Alkylphosphonate utilization operon protein PhnA
CH92_RS17095	COG4993	Dehydrogenase
CH92_RS17100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH92_RS17100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH92_RS17100	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CH92_RS17105	COG1105	Belongs to the carbohydrate kinase PfkB family
CH92_RS17110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH92_RS17110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH92_RS17125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH92_RS17150	COG0534	Mate efflux family protein
CH92_RS17185	COG0346	lactoylglutathione lyase activity
CH92_RS17255	COG1253	flavin adenine dinucleotide binding
CH92_RS17305	COG1739	Uncharacterized protein family UPF0029
CH92_RS17310	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CH92_RS17315	COG0583	DNA-binding transcription factor activity
CH92_RS17325	COG2814	Major facilitator Superfamily
CH92_RS17330	COG1309	transcriptional regulator
CH92_RS17360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH92_RS17365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH92_RS17370	COG1538	Outer membrane efflux protein
CH92_RS17380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH92_RS17380	COG2169	Transcriptional regulator
CH92_RS17390	COG0084	hydrolase, TatD family'
CH92_RS17405	COG0840	transmembrane signaling receptor activity
CH92_RS17415	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH92_RS17420	COG1515	deoxyribonuclease V activity
CH92_RS17425	COG4977	sequence-specific DNA binding
CH92_RS17430	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH92_RS17435	COG0180	Tryptophanyl-tRNA synthetase
CH92_RS17465	COG1252	NADH dehydrogenase
CH92_RS17535	COG1032	radical SAM domain protein
CH92_RS17570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH92_RS17580	COG0305	Participates in initiation and elongation during chromosome replication
CH92_RS17585	COG0359	binds to the 23S rRNA
CH92_RS17595	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH92_RS17600	COG0360	Binds together with S18 to 16S ribosomal RNA
CH92_RS17610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH92_RS17615	COG0557	exoribonuclease II activity
CH92_RS17630	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CH92_RS17635	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CH92_RS17640	COG0330	HflC and HflK could
CH92_RS17645	COG0330	HflC and HflK could
CH92_RS17650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH92_RS17655	COG1923	regulation of RNA biosynthetic process
CH92_RS17660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CH92_RS17665	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CH92_RS17670	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH92_RS17675	COG0802	atpase or kinase
CH92_RS17680	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH92_RS17680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH92_RS17700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH92_RS17710	COG0531	amino acid
CH92_RS17715	COG4303	Ethanolamine ammonia lyase large subunit
CH92_RS17720	COG4302	ethanolamine ammonia-lyase activity
CH92_RS17730	COG3228	Belongs to the MtfA family
CH92_RS17750	COG3384	dioxygenase
CH92_RS17755	COG1234	tRNA 3'-trailer cleavage
CH92_RS17760	COG0583	DNA-binding transcription factor activity
CH92_RS17765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CH92_RS17770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH92_RS17775	COG2828	Protein conserved in bacteria
CH92_RS17790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH92_RS17800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH92_RS17805	COG1120	ATPase activity
CH92_RS17810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_RS17830	COG0784	Response regulator, receiver
CH92_RS17830	COG4191	Histidine kinase
CH92_RS17835	COG3546	catalase activity
CH92_RS17845	COG0189	ligase activity
CH92_RS17845	COG4067	protein conserved in archaea
CH92_RS17860	COG1230	cation diffusion facilitator family transporter
CH92_RS17870	COG0730	response to heat
CH92_RS17875	COG1722	exodeoxyribonuclease VII activity
CH92_RS17880	COG0142	geranyltranstransferase activity
CH92_RS17885	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CH92_RS17890	COG4206	TonB-dependent receptor
CH92_RS17895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH92_RS17905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CH92_RS17910	COG3577	Aspartyl protease
CH92_RS17915	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH92_RS17920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH92_RS17925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CH92_RS17930	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CH92_RS17950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH92_RS17950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH92_RS17965	COG2264	protein methyltransferase activity
CH92_RS17975	COG3118	belongs to the thioredoxin family
CH92_RS17985	COG1946	Acyl-CoA thioesterase
CH92_RS17995	COG0123	including yeast histone deacetylase and acetoin utilization protein
CH92_RS18015	COG0513	Belongs to the DEAD box helicase family
CH92_RS18035	COG1028	Short-chain dehydrogenase reductase Sdr
CH92_RS18045	COG1643	Atp-dependent helicase
CH92_RS18065	COG1522	sequence-specific DNA binding
CH92_RS18095	COG0411	ABC transporter
CH92_RS18130	COG0559	Belongs to the binding-protein-dependent transport system permease family
CH92_RS18135	COG0829	nickel cation binding
CH92_RS18140	COG0831	urea catabolic process
CH92_RS18150	COG0832	Belongs to the urease beta subunit family
CH92_RS18155	COG0804	urea catabolic process
CH92_RS18160	COG1953	Uracil, thiamine, allantoin
CH92_RS18175	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH92_RS18185	COG2814	Major facilitator Superfamily
CH92_RS18190	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CH92_RS18205	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CH92_RS18210	COG0830	nickel cation binding
CH92_RS18215	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH92_RS18225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH92_RS18230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH92_RS18240	COG1960	acyl-CoA dehydrogenase activity
CH92_RS18245	COG2205	protein histidine kinase activity
CH92_RS18245	COG3437	response regulator, receiver
CH92_RS18245	COG3850	Histidine kinase
CH92_RS18245	COG4999	Histidine kinase
CH92_RS18250	COG0351	phosphomethylpyrimidine kinase
CH92_RS18260	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CH92_RS18275	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CH92_RS18280	COG1702	phosphate starvation-inducible protein PhoH
CH92_RS18285	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CH92_RS18290	COG4535	Mg2 and Co2 transporter CorC
CH92_RS18295	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH92_RS18310	COG0495	leucyl-tRNA aminoacylation
CH92_RS18330	COG2951	lytic endotransglycosylase activity
CH92_RS18340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CH92_RS18345	COG0321	lipoyl(octanoyl) transferase activity
CH92_RS18350	COG2921	Belongs to the UPF0250 family
CH92_RS18355	COG1686	Belongs to the peptidase S11 family
CH92_RS18365	COG2951	lytic endotransglycosylase activity
CH92_RS18370	COG0772	Belongs to the SEDS family
CH92_RS18375	COG0768	penicillin binding
CH92_RS18380	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CH92_RS18390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CH92_RS18395	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CH92_RS18400	COG0586	Pfam SNARE associated Golgi protein
CH92_RS18410	COG1346	cytolysis
CH92_RS18430	COG0702	epimerase
CH92_RS18435	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH92_RS18445	COG1162	GTPase activity
CH92_RS18450	COG1360	Flagellar Motor Protein
CH92_RS18455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CH92_RS18470	COG0688	phosphatidylethanolamine metabolic process
CH92_RS18485	COG0560	Phosphoserine phosphatase
CH92_RS18485	COG3830	Belongs to the UPF0237 family
CH92_RS18520	COG3150	esterase
CH92_RS18525	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CH92_RS18535	COG0494	nUDIX hydrolase
CH92_RS18550	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CH92_RS18555	COG1538	Outer membrane efflux protein
CH92_RS18560	COG1519	Transferase
CH92_RS18575	COG0667	Aldo Keto reductase
CH92_RS18585	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CH92_RS18585	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CH92_RS18600	COG1132	(ABC) transporter
CH92_RS18625	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CH92_RS18630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CH92_RS18645	COG0438	transferase activity, transferring glycosyl groups
CH92_RS18650	COG2192	nodulation
CH92_RS18670	COG0438	transferase activity, transferring glycosyl groups
CH92_RS18675	COG0859	PFAM glycosyl transferase family 9
CH92_RS18680	COG0859	PFAM glycosyl transferase family 9
CH92_RS18690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CH92_RS18715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CH92_RS18720	COG1960	acyl-CoA dehydrogenase activity
CH92_RS18725	COG1960	acyl-CoA dehydrogenase activity
CH92_RS18730	COG3706	GGDEF domain
CH92_RS18735	COG1960	acyl-CoA dehydrogenase activity
CH92_RS18755	COG1073	alpha beta
CH92_RS18755	COG2226	methyltransferase
CH92_RS18760	COG0156	8-amino-7-oxononanoate synthase activity
CH92_RS18765	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CH92_RS18770	COG1040	competence protein
CH92_RS18775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH92_RS18780	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH92_RS18825	COG1960	acyl-CoA dehydrogenase activity
CH92_RS18830	COG3263	regulation of cellular component size
CH92_RS18835	COG1196	nuclear chromosome segregation
CH92_RS18835	COG3264	Mechanosensitive ion channel
CH92_RS18840	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CH92_RS18855	COG4104	PAAR repeat-containing protein
CH92_RS18955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH92_RS18985	COG0330	HflC and HflK could
CH92_RS19010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH92_RS19045	COG1595	DNA-templated transcription, initiation
CH92_RS19050	COG3712	iron ion homeostasis
CH92_RS19075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH92_RS19090	COG0513	Belongs to the DEAD box helicase family
CH92_RS19100	COG1289	transmembrane transporter activity
CH92_RS19105	COG2081	HI0933 family
CH92_RS19135	COG2204	response regulator
CH92_RS19140	COG0191	fructose-bisphosphate aldolase activity
CH92_RS19150	COG0126	phosphoglycerate kinase activity
CH92_RS19155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CH92_RS19160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH92_RS19165	COG0583	DNA-binding transcription factor activity
CH92_RS19170	COG2175	clavaminate synthase activity
CH92_RS19180	COG2226	methyltransferase
CH92_RS19185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CH92_RS19195	COG0842	Transport permease protein
CH92_RS19200	COG1131	(ABC) transporter
CH92_RS19205	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CH92_RS19230	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CH92_RS19235	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CH92_RS19255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH92_RS19260	COG2353	YceI-like domain
CH92_RS19265	COG3038	cytochrome b561
CH92_RS19275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH92_RS19290	COG0643	Histidine kinase
CH92_RS19290	COG0784	Response regulator, receiver
CH92_RS19290	COG2198	Histidine kinase
CH92_RS19330	COG1678	Uncharacterized ACR, COG1678
CH92_RS19345	COG0540	Belongs to the ATCase OTCase family
CH92_RS19395	COG1160	GTP binding
CH92_RS19400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CH92_RS19405	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CH92_RS19405	COG2813	Specifically methylates the guanine in position
CH92_RS19415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH92_RS19420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH92_RS19435	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CH92_RS19440	COG2022	thiamine diphosphate biosynthetic process
CH92_RS19450	COG2363	Small membrane protein
CH92_RS19455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH92_RS19470	COG2177	Part of the ABC transporter FtsEX involved in
CH92_RS19475	COG2884	Cell division ATP-binding protein ftsE
CH92_RS19480	COG0552	protein localization to endoplasmic reticulum
CH92_RS19485	COG0612	Peptidase, M16
CH92_RS19490	COG0612	Peptidase, M16
CH92_RS19495	COG0742	ribosomal rna small subunit methyltransferase
CH92_RS19505	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CH92_RS19510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH92_RS19520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CH92_RS19530	COG0693	protein deglycase activity
CH92_RS19535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CH92_RS19545	COG2207	Transcriptional regulator
CH92_RS19550	COG2831	hemolysin activation secretion protein
CH92_RS19560	COG0129	dihydroxy-acid dehydratase activity
CH92_RS19570	COG2233	PERMEase
CH92_RS19580	COG2233	PERMEase
CH92_RS19585	COG0579	oxidoreductase
CH92_RS19605	COG0584	glycerophosphoryl diester phosphodiesterase
CH92_RS19610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CH92_RS19655	COG0704	Plays a role in the regulation of phosphate uptake
CH92_RS19660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CH92_RS19665	COG0581	inorganic phosphate transmembrane transporter activity
CH92_RS19680	COG1607	acyl-coa hydrolase
CH92_RS19685	COG5001	Diguanylate cyclase
CH92_RS19685	COG3706	GGDEF domain
CH92_RS19685	COG2203	Gaf domain
CH92_RS19685	COG4251	negative regulation of phosphorylation
CH92_RS19705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH92_RS19720	COG1283	sodium-dependent phosphate transmembrane transporter activity
CH92_RS19730	COG2358	TRAP transporter, solute receptor (TAXI family
CH92_RS19740	COG0642	Histidine kinase
CH92_RS19775	COG0700	Nucleoside recognition
CH92_RS19795	COG2204	response regulator
CH92_RS19800	COG5002	protein histidine kinase activity
CH92_RS19810	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH92_RS19835	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CH92_RS19840	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CH92_RS19840	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CH92_RS19855	COG1178	ABC-type Fe3 transport system permease component
CH92_RS19870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH92_RS19875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH92_RS19880	COG0006	proline dipeptidase activity
CH92_RS19885	COG3079	Belongs to the UPF0149 family
CH92_RS19900	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH92_RS19915	COG0604	alcohol dehydrogenase
CH92_RS19920	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CH92_RS19935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CH92_RS19940	COG4942	peptidase
CH92_RS19945	COG0793	Belongs to the peptidase S41A family
CH92_RS19950	COG2861	carbohydrate metabolic process
CH92_RS19970	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CH92_RS19985	COG0131	Imidazoleglycerol-phosphate dehydratase
CH92_RS20000	COG1194	a g-specific adenine glycosylase
CH92_RS20005	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CH92_RS20015	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CH92_RS20040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH92_RS20065	COG0676	glucose-6-phosphate 1-epimerase activity
CH92_RS20100	COG0583	DNA-binding transcription factor activity
CH92_RS20105	COG1027	Aspartate ammonia-lyase
CH92_RS20120	COG1115	amino acid carrier protein
CH92_RS20125	COG0252	asparaginase activity
CH92_RS20130	COG2205	protein histidine kinase activity
CH92_RS20135	COG1218	3'(2'),5'-bisphosphate nucleotidase
CH92_RS20140	COG0494	nUDIX hydrolase
CH92_RS20145	COG1011	Hydrolase
CH92_RS20155	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CH92_RS20165	COG3383	formate dehydrogenase (NAD+) activity
CH92_RS20180	COG1910	domain protein
CH92_RS20190	COG0824	Thioesterase
CH92_RS20195	COG1454	alcohol dehydrogenase
CH92_RS20200	COG1960	acyl-CoA dehydrogenase activity
CH92_RS20205	COG1250	3-hydroxyacyl-CoA dehydrogenase
CH92_RS20205	COG1024	Enoyl-CoA hydratase
CH92_RS20215	COG1278	Cold shock
CH92_RS20220	COG5002	protein histidine kinase activity
CH92_RS20235	COG0445	tRNA wobble uridine modification
CH92_RS20245	COG0667	Aldo Keto reductase
CH92_RS20260	COG0514	ATP-dependent DNA helicase (RecQ)
CH92_RS20275	COG0778	Nitroreductase
CH92_RS20300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CH92_RS20330	COG0463	Glycosyl transferase, family 2
CH92_RS20340	COG0726	polysaccharide deacetylase
CH92_RS20370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH92_RS20375	COG0189	ligase activity
CH92_RS20375	COG4067	protein conserved in archaea
CH92_RS20380	COG0189	ligase activity
CH92_RS20395	COG2183	response to ionizing radiation
CH92_RS20405	COG2918	glutathione biosynthetic process
CH92_RS20425	COG0306	phosphate transporter
CH92_RS20430	COG1392	Phosphate transport regulator
CH92_RS20440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH92_RS20465	COG1764	response to oxidative stress
CH92_RS20470	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CH92_RS20520	COG0586	Pfam SNARE associated Golgi protein
CH92_RS20540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH92_RS20545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH92_RS20545	COG2010	Cytochrome c
CH92_RS20560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH92_RS20565	COG1127	ABC transporter
CH92_RS20570	COG3218	ABC-type transport auxiliary lipoprotein component
CH92_RS20570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH92_RS20600	COG1091	dTDP-4-dehydrorhamnose reductase activity
CH92_RS20650	COG1177	transmembrane transport
CH92_RS20655	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH92_RS20660	COG3842	ATPase activity
CH92_RS20680	COG0174	glutamine synthetase
CH92_RS20685	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CH92_RS20690	COG0174	glutamine synthetase
CH92_RS20715	COG2957	Belongs to the agmatine deiminase family
CH92_RS20720	COG2199	diguanylate cyclase activity
CH92_RS20730	COG0745	RESPONSE REGULATOR receiver
CH92_RS20735	COG5002	protein histidine kinase activity
CH92_RS20740	COG4565	transcriptional regulatory protein
CH92_RS20750	COG5002	protein histidine kinase activity
CH92_RS20755	COG0745	RESPONSE REGULATOR receiver
CH92_RS20775	COG1012	belongs to the aldehyde dehydrogenase family
CH92_RS20780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CH92_RS20785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CH92_RS20790	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CH92_RS20815	COG1960	acyl-CoA dehydrogenase activity
CH92_RS20820	COG1024	Enoyl-CoA hydratase
CH92_RS20820	COG1250	3-hydroxyacyl-CoA dehydrogenase
CH92_RS20840	COG1960	acyl-CoA dehydrogenase activity
CH92_RS20860	COG2188	Transcriptional regulator
CH92_RS20865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CH92_RS20870	COG1960	acyl-CoA dehydrogenase activity
CH92_RS20880	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CH92_RS20880	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CH92_RS20905	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CH92_RS20910	COG3835	regulator
CH92_RS20915	COG0402	S-adenosylhomocysteine deaminase activity
CH92_RS20920	COG1079	Belongs to the binding-protein-dependent transport system permease family
CH92_RS20930	COG3845	ABC transporter
CH92_RS20950	COG1335	isochorismatase
CH92_RS20955	COG1309	transcriptional regulator
CH92_RS20960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH92_RS20965	COG1335	isochorismatase
CH92_RS20970	COG0251	oxidation-reduction process
CH92_RS20975	COG0596	Alpha beta hydrolase
CH92_RS20980	COG0778	Nitroreductase
CH92_RS20985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH92_RS21005	COG1304	FMN binding
CH92_RS21010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH92_RS21035	COG4948	Mandelate Racemase Muconate Lactonizing
CH92_RS21040	COG1609	Transcriptional regulator
CH92_RS21045	COG0129	dihydroxy-acid dehydratase activity
CH92_RS21070	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH92_RS21085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH92_RS21105	COG3052	prosthetic group binding
CH92_RS21110	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CH92_RS21120	COG1238	metal cluster binding
CH92_RS21135	COG2358	TRAP transporter, solute receptor (TAXI family
CH92_RS21160	COG3712	iron ion homeostasis
CH92_RS21165	COG1595	DNA-templated transcription, initiation
CH92_RS21180	COG0523	cobalamin synthesis protein
CH92_RS21195	COG4251	negative regulation of phosphorylation
CH92_RS21200	COG0784	Response regulator, receiver
CH92_RS21205	COG0784	Response regulator, receiver
CH92_RS21205	COG4191	Histidine kinase
CH92_RS21245	COG4774	siderophore transport
CH92_RS21255	COG1595	DNA-templated transcription, initiation
CH92_RS21285	COG2826	transposase and inactivated derivatives, IS30 family
CH92_RS21295	COG0515	serine threonine protein kinase
CH92_RS21295	COG2815	serine threonine protein kinase
CH92_RS21310	COG1061	Type III restriction enzyme res subunit
CH92_RS21350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CH92_RS21355	COG1349	DNA-binding transcription factor activity
CH92_RS21360	COG0840	transmembrane signaling receptor activity
CH92_RS21365	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CH92_RS21370	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CH92_RS21375	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CH92_RS21380	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CH92_RS21385	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CH92_RS21390	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CH92_RS21395	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CH92_RS21410	COG3312	ion transport
CH92_RS21415	COG1475	DNA binding
CH92_RS21420	COG1192	Involved in chromosome partitioning
CH92_RS21425	COG0357	Ribosomal RNA small subunit methyltransferase G
CH92_RS21430	COG0445	tRNA wobble uridine modification
CH92_RS21435	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CH92_RS21440	COG0706	membrane insertase activity
CH92_RS21445	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CH92_RS21485	COG0463	Glycosyl transferase, family 2
CH92_RS21515	COG1309	transcriptional regulator
CH92_RS21615	COG1399	metal-binding, possibly nucleic acid-binding protein
CH92_RS21650	COG0727	PFAM Uncharacterised protein family (UPF0153)
CH92_RS21680	COG3130	regulation of translation
CH92_RS21685	COG0653	protein targeting
CH92_RS21795	COG0594	ribonuclease P activity
CH92_RS21800	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH92_RS21885	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CH92_RS22260	COG0494	nUDIX hydrolase
CH92_RS22270	COG1278	Cold shock
CH92_RS22290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH92_RS22365	COG0732	type I restriction modification DNA specificity domain