locus-tag	class	description
PszF2a_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PszF2a_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PszF2a_RS00030	COG3706	GGDEF domain
PszF2a_RS00045	COG0751	glycine-tRNA ligase activity
PszF2a_RS00055	COG2818	Glycosylase
PszF2a_RS00075	COG1126	abc transporter atp-binding protein
PszF2a_RS00080	COG0765	amino acid transport
PszF2a_RS00085	COG0765	amino acid transport
PszF2a_RS00090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PszF2a_RS00095	COG0569	domain protein
PszF2a_RS00100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PszF2a_RS00105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PszF2a_RS00110	COG0242	peptide deformylase activity
PszF2a_RS00120	COG0758	DNA mediated transformation
PszF2a_RS00125	COG0009	L-threonylcarbamoyladenylate synthase
PszF2a_RS00135	COG0408	coproporphyrinogen oxidase activity
PszF2a_RS00140	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PszF2a_RS00155	COG1686	Belongs to the peptidase S11 family
PszF2a_RS00195	COG2011	ABC-type metal ion transport system permease component
PszF2a_RS00210	COG1451	nucleotide metabolic process
PszF2a_RS00215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PszF2a_RS00220	COG1121	(ABC) transporter
PszF2a_RS00225	COG0735	belongs to the Fur family
PszF2a_RS00235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PszF2a_RS00240	COG1012	belongs to the aldehyde dehydrogenase family
PszF2a_RS00260	COG0745	RESPONSE REGULATOR receiver
PszF2a_RS00265	COG5002	protein histidine kinase activity
PszF2a_RS00275	COG0745	RESPONSE REGULATOR receiver
PszF2a_RS00280	COG5002	protein histidine kinase activity
PszF2a_RS00285	COG0745	RESPONSE REGULATOR receiver
PszF2a_RS00290	COG4191	Histidine kinase
PszF2a_RS00300	COG3706	GGDEF domain
PszF2a_RS00310	COG2957	Belongs to the agmatine deiminase family
PszF2a_RS00325	COG0174	glutamine synthetase
PszF2a_RS00330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PszF2a_RS00335	COG0174	glutamine synthetase
PszF2a_RS00360	COG3842	ATPase activity
PszF2a_RS00365	COG1176	ABC-type spermidine putrescine transport system, permease component I
PszF2a_RS00370	COG1177	transmembrane transport
PszF2a_RS00440	COG0842	Transport permease protein
PszF2a_RS00445	COG0842	Transport permease protein
PszF2a_RS00445	COG1129	ABC transporter
PszF2a_RS00450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PszF2a_RS00465	COG1127	ABC transporter
PszF2a_RS00470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PszF2a_RS00475	COG0753	catalase activity
PszF2a_RS00480	COG2010	Cytochrome c
PszF2a_RS00495	COG3909	cytochrome
PszF2a_RS00510	COG1250	3-hydroxyacyl-CoA dehydrogenase
PszF2a_RS00510	COG1024	Enoyl-CoA hydratase
PszF2a_RS00515	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS00520	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS00525	COG2814	Major facilitator Superfamily
PszF2a_RS00545	COG0318	PFAM AMP-dependent synthetase and ligase
PszF2a_RS00550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PszF2a_RS00555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PszF2a_RS00570	COG1611	Belongs to the LOG family
PszF2a_RS00615	COG2207	Transcriptional regulator
PszF2a_RS00625	COG2249	NAD(P)H dehydrogenase (quinone) activity
PszF2a_RS00700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PszF2a_RS00705	COG0583	DNA-binding transcription factor activity
PszF2a_RS00755	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PszF2a_RS00800	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PszF2a_RS00830	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PszF2a_RS00855	COG1191	sigma factor activity
PszF2a_RS00860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PszF2a_RS00880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PszF2a_RS00895	COG1558	bacterial-type flagellum-dependent cell motility
PszF2a_RS00900	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PszF2a_RS00910	COG4787	bacterial-type flagellum-dependent cell motility
PszF2a_RS00915	COG4786	Flagellar basal body rod
PszF2a_RS00925	COG1706	bacterial-type flagellum-dependent cell motility
PszF2a_RS00930	COG0741	lytic transglycosylase activity
PszF2a_RS00935	COG1256	bacterial-type flagellum assembly
PszF2a_RS00935	COG4786	Flagellar basal body rod
PszF2a_RS00950	COG2706	6-phosphogluconolactonase activity
PszF2a_RS00955	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS00960	COG4191	Histidine kinase
PszF2a_RS00960	COG0784	Response regulator, receiver
PszF2a_RS00985	COG3795	YCII-related domain
PszF2a_RS00990	COG4941	Belongs to the sigma-70 factor family
PszF2a_RS00995	COG2204	response regulator
PszF2a_RS01000	COG4191	Histidine kinase
PszF2a_RS01010	COG0589	response to stress
PszF2a_RS01015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PszF2a_RS01025	COG0509	glycine decarboxylation via glycine cleavage system
PszF2a_RS01040	COG3276	selenocysteine insertion sequence binding
PszF2a_RS01045	COG1921	L-seryl-tRNASec selenium transferase activity
PszF2a_RS01050	COG3058	Necessary for formate dehydrogenase activity
PszF2a_RS01055	COG2864	formate dehydrogenase
PszF2a_RS01060	COG0437	4 iron, 4 sulfur cluster binding
PszF2a_RS01075	COG1764	response to oxidative stress
PszF2a_RS01090	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PszF2a_RS01095	COG0210	DNA helicase
PszF2a_RS01105	COG0826	peptidase U32
PszF2a_RS01110	COG2841	Protein conserved in bacteria
PszF2a_RS01115	COG0527	aspartate kinase activity
PszF2a_RS01120	COG5285	phytanoyl-CoA dioxygenase
PszF2a_RS01125	COG1917	Cupin 2, conserved barrel domain protein
PszF2a_RS01130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PszF2a_RS01140	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PszF2a_RS01145	COG0837	glucose binding
PszF2a_RS01145	COG1737	Transcriptional regulator
PszF2a_RS01155	COG0583	DNA-binding transcription factor activity
PszF2a_RS01160	COG0439	Biotin carboxylase
PszF2a_RS01165	COG5016	pyruvate
PszF2a_RS01165	COG0511	ligase activity, forming carbon-carbon bonds
PszF2a_RS01180	COG2066	Belongs to the glutaminase family
PszF2a_RS01195	COG0252	asparaginase activity
PszF2a_RS01200	COG1115	amino acid carrier protein
PszF2a_RS01225	COG1301	dicarboxylic acid transport
PszF2a_RS01235	COG0583	DNA-binding transcription factor activity
PszF2a_RS01245	COG1082	Xylose isomerase domain protein TIM barrel
PszF2a_RS01245	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PszF2a_RS01250	COG2205	protein histidine kinase activity
PszF2a_RS01280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PszF2a_RS01290	COG4208	sulfate ABC transporter
PszF2a_RS01300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PszF2a_RS01305	COG5583	Uncharacterized small protein (DUF2292)
PszF2a_RS01315	COG0450	alkyl hydroperoxide reductase
PszF2a_RS01320	COG0431	NADPH-dependent FMN reductase
PszF2a_RS01325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PszF2a_RS01330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PszF2a_RS01335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PszF2a_RS01340	COG1116	anion transmembrane transporter activity
PszF2a_RS01365	COG0583	DNA-binding transcription factor activity
PszF2a_RS01370	COG2814	Major facilitator Superfamily
PszF2a_RS01395	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PszF2a_RS01400	COG1764	response to oxidative stress
PszF2a_RS01415	COG2989	Protein conserved in bacteria
PszF2a_RS01425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PszF2a_RS01435	COG1392	Phosphate transport regulator
PszF2a_RS01440	COG0306	phosphate transporter
PszF2a_RS01455	COG2918	glutathione biosynthetic process
PszF2a_RS01465	COG2183	response to ionizing radiation
PszF2a_RS01470	COG3118	belongs to the thioredoxin family
PszF2a_RS01470	COG0457	Tetratricopeptide repeat
PszF2a_RS01475	COG1215	transferase activity, transferring glycosyl groups
PszF2a_RS01480	COG1215	transferase activity, transferring glycosyl groups
PszF2a_RS01485	COG1192	Involved in chromosome partitioning
PszF2a_RS01495	COG2194	sulfuric ester hydrolase activity
PszF2a_RS01525	COG0189	ligase activity
PszF2a_RS01530	COG0189	ligase activity
PszF2a_RS01530	COG4067	protein conserved in archaea
PszF2a_RS01535	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PszF2a_RS01545	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PszF2a_RS01555	COG0778	Nitroreductase
PszF2a_RS01565	COG0514	ATP-dependent DNA helicase (RecQ)
PszF2a_RS01570	COG0840	transmembrane signaling receptor activity
PszF2a_RS01585	COG0667	Aldo Keto reductase
PszF2a_RS01610	COG4191	Histidine kinase
PszF2a_RS01610	COG0784	Response regulator, receiver
PszF2a_RS01615	COG2205	protein histidine kinase activity
PszF2a_RS01625	COG2172	sigma factor antagonist activity
PszF2a_RS01630	COG1366	Belongs to the anti-sigma-factor antagonist family
PszF2a_RS01645	COG1024	Enoyl-CoA hydratase
PszF2a_RS01645	COG1250	3-hydroxyacyl-CoA dehydrogenase
PszF2a_RS01650	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS01655	COG1454	alcohol dehydrogenase
PszF2a_RS01670	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PszF2a_RS01675	COG4191	Histidine kinase
PszF2a_RS01675	COG0784	Response regulator, receiver
PszF2a_RS01680	COG1011	Hydrolase
PszF2a_RS01685	COG0494	nUDIX hydrolase
PszF2a_RS01690	COG1218	3'(2'),5'-bisphosphate nucleotidase
PszF2a_RS01705	COG0058	SHG alpha-glucan phosphorylase activity
PszF2a_RS01710	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PszF2a_RS01740	COG1490	D-aminoacyl-tRNA deacylase activity
PszF2a_RS01760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PszF2a_RS01765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PszF2a_RS01770	COG0140	phosphoribosyl-ATP diphosphatase activity
PszF2a_RS01775	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PszF2a_RS01780	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PszF2a_RS01790	COG2226	methyltransferase
PszF2a_RS01800	COG0840	transmembrane signaling receptor activity
PszF2a_RS01810	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PszF2a_RS01820	COG0243	molybdopterin cofactor binding
PszF2a_RS01840	COG3852	Histidine kinase
PszF2a_RS01860	COG0301	tRNA thio-modification
PszF2a_RS01860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PszF2a_RS01865	COG1217	gtp-binding protein TYPA
PszF2a_RS01875	COG3493	citrate carrier protein
PszF2a_RS01880	COG3290	protein histidine kinase activity
PszF2a_RS01885	COG4565	transcriptional regulatory protein
PszF2a_RS01900	COG3210	domain, Protein
PszF2a_RS01900	COG3210	domain, Protein
PszF2a_RS01950	COG2204	response regulator
PszF2a_RS01955	COG4807	Protein conserved in bacteria
PszF2a_RS01980	COG5001	Diguanylate cyclase
PszF2a_RS01985	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PszF2a_RS02000	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS02005	COG0003	Pfam Anion-transporting ATPase
PszF2a_RS02015	COG1966	Carbon starvation protein
PszF2a_RS02030	COG1320	monovalent cation:proton antiporter activity
PszF2a_RS02050	COG0651	ATP synthesis coupled electron transport
PszF2a_RS02055	COG0651	ATP synthesis coupled electron transport
PszF2a_RS02095	COG2197	response regulator
PszF2a_RS02120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PszF2a_RS02125	COG0277	FAD linked oxidase domain protein
PszF2a_RS02130	COG0179	Fumarylacetoacetate (FAA) hydrolase
PszF2a_RS02150	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PszF2a_RS02155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PszF2a_RS02165	COG0702	epimerase
PszF2a_RS02180	COG0494	nUDIX hydrolase
PszF2a_RS02195	COG0730	response to heat
PszF2a_RS02200	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PszF2a_RS02205	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PszF2a_RS02210	COG1192	Involved in chromosome partitioning
PszF2a_RS02220	COG0559	Belongs to the binding-protein-dependent transport system permease family
PszF2a_RS02230	COG0411	ABC transporter
PszF2a_RS02250	COG0739	heme binding
PszF2a_RS02285	COG1253	flavin adenine dinucleotide binding
PszF2a_RS02300	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PszF2a_RS02305	COG3161	chorismate lyase activity
PszF2a_RS02310	COG2186	Transcriptional regulator
PszF2a_RS02315	COG0277	FAD linked oxidase domain protein
PszF2a_RS02320	COG0277	FAD linked oxidase domain protein
PszF2a_RS02325	COG0247	lactate metabolic process
PszF2a_RS02330	COG3193	protein, possibly involved in utilization of glycolate and propanediol
PszF2a_RS02335	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PszF2a_RS02340	COG1620	l-lactate permease
PszF2a_RS02365	COG0583	DNA-binding transcription factor activity
PszF2a_RS02370	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS02380	COG0604	alcohol dehydrogenase
PszF2a_RS02385	COG0583	DNA-binding transcription factor activity
PszF2a_RS02390	COG1704	LemA family
PszF2a_RS02395	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PszF2a_RS02415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PszF2a_RS02435	COG2080	2 iron, 2 sulfur cluster binding
PszF2a_RS02455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PszF2a_RS02460	COG1758	RNA polymerase activity
PszF2a_RS02470	COG1561	YicC-like family, N-terminal region
PszF2a_RS02475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PszF2a_RS02485	COG0708	Exodeoxyribonuclease III
PszF2a_RS02490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PszF2a_RS02505	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PszF2a_RS02515	COG0756	dUTP diphosphatase activity
PszF2a_RS02520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PszF2a_RS02525	COG2003	Belongs to the UPF0758 family
PszF2a_RS02540	COG1250	3-hydroxyacyl-CoA dehydrogenase
PszF2a_RS02560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PszF2a_RS02565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PszF2a_RS02575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PszF2a_RS02580	COG0251	oxidation-reduction process
PszF2a_RS02600	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PszF2a_RS02615	COG0366	Alpha amylase catalytic
PszF2a_RS02620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PszF2a_RS02630	COG1454	alcohol dehydrogenase
PszF2a_RS02640	COG1414	Transcriptional regulator
PszF2a_RS02645	COG1272	protein, Hemolysin III
PszF2a_RS02650	COG0210	DNA helicase
PszF2a_RS02660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PszF2a_RS02665	COG0606	chelatase, subunit chli
PszF2a_RS02675	COG0347	Belongs to the P(II) protein family
PszF2a_RS02680	COG0004	ammonium transporteR
PszF2a_RS02685	COG0004	ammonium transporteR
PszF2a_RS02690	COG0432	Pfam Uncharacterised protein family UPF0047
PszF2a_RS02705	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PszF2a_RS02715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PszF2a_RS02730	COG1965	Belongs to the frataxin family
PszF2a_RS02735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PszF2a_RS02775	COG0165	Argininosuccinate lyase
PszF2a_RS02780	COG3275	phosphorelay sensor kinase activity
PszF2a_RS02790	COG0181	hydroxymethylbilane synthase activity
PszF2a_RS02810	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PszF2a_RS02830	COG0488	(ABC) transporter
PszF2a_RS02840	COG0861	Integral membrane protein TerC family
PszF2a_RS02845	COG1280	lysine exporter protein (LysE YggA)
PszF2a_RS02850	COG1671	Belongs to the UPF0178 family
PszF2a_RS02865	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PszF2a_RS02875	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PszF2a_RS02880	COG0248	Ppx GppA phosphatase
PszF2a_RS02895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PszF2a_RS02910	COG0018	arginyl-trna synthetase
PszF2a_RS02915	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PszF2a_RS02920	COG0254	rRNA binding
PszF2a_RS02930	COG0281	malic enzyme
PszF2a_RS02965	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PszF2a_RS02970	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PszF2a_RS02980	COG0070	glutamate synthase
PszF2a_RS02980	COG0069	glutamate synthase activity
PszF2a_RS02980	COG0067	glutamate synthase
PszF2a_RS02985	COG0493	'glutamate synthase
PszF2a_RS02995	COG2814	Major facilitator Superfamily
PszF2a_RS03000	COG0583	DNA-binding transcription factor activity
PszF2a_RS03015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PszF2a_RS03020	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS03030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PszF2a_RS03060	COG2986	histidine ammonia-lyase
PszF2a_RS03085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PszF2a_RS03090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PszF2a_RS03105	COG3118	belongs to the thioredoxin family
PszF2a_RS03110	COG2873	o-acetylhomoserine
PszF2a_RS03115	COG3273	potassium ion transport
PszF2a_RS03115	COG0471	metal ion transport
PszF2a_RS03125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PszF2a_RS03130	COG0358	DNA primase activity
PszF2a_RS03135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PszF2a_RS03140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PszF2a_RS03145	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PszF2a_RS03160	COG0617	tRNA 3'-terminal CCA addition
PszF2a_RS03165	COG2719	SpoVR family
PszF2a_RS03170	COG2718	Belongs to the UPF0229 family
PszF2a_RS03175	COG2766	serine protein kinase
PszF2a_RS03180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PszF2a_RS03185	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PszF2a_RS03190	COG2967	ApaG domain
PszF2a_RS03195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PszF2a_RS03200	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PszF2a_RS03205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PszF2a_RS03210	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PszF2a_RS03220	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PszF2a_RS03225	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PszF2a_RS03240	COG2197	response regulator
PszF2a_RS03245	COG3842	ATPase activity
PszF2a_RS03255	COG1176	ABC-type spermidine putrescine transport system, permease component I
PszF2a_RS03260	COG1177	transmembrane transport
PszF2a_RS03270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PszF2a_RS03275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PszF2a_RS03280	COG0546	phosphoglycolate phosphatase activity
PszF2a_RS03290	COG0512	Glutamine amidotransferase of anthranilate synthase
PszF2a_RS03295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PszF2a_RS03300	COG0134	indole-3-glycerol-phosphate synthase activity
PszF2a_RS03310	COG1765	OsmC-like protein
PszF2a_RS03315	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
PszF2a_RS03320	COG0537	adenosine 5'-monophosphoramidase activity
PszF2a_RS03325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PszF2a_RS03335	COG1981	membrane
PszF2a_RS03340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PszF2a_RS03345	COG0316	Belongs to the HesB IscA family
PszF2a_RS03350	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PszF2a_RS03355	COG0739	heme binding
PszF2a_RS03360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PszF2a_RS03390	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PszF2a_RS03390	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PszF2a_RS03395	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PszF2a_RS03420	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PszF2a_RS03440	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PszF2a_RS03445	COG0081	regulation of translation
PszF2a_RS03450	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PszF2a_RS03455	COG0222	ribosome binding
PszF2a_RS03460	COG0085	RNA polymerase activity
PszF2a_RS03465	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PszF2a_RS03470	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PszF2a_RS03475	COG0049	tRNA binding
PszF2a_RS03480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PszF2a_RS03485	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PszF2a_RS03490	COG0051	transcription antitermination factor activity, RNA binding
PszF2a_RS03495	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PszF2a_RS03500	COG0088	Forms part of the polypeptide exit tunnel
PszF2a_RS03505	COG0089	rRNA binding
PszF2a_RS03510	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PszF2a_RS03515	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PszF2a_RS03520	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PszF2a_RS03525	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PszF2a_RS03530	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PszF2a_RS03535	COG0255	Belongs to the universal ribosomal protein uL29 family
PszF2a_RS03540	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PszF2a_RS03545	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PszF2a_RS03550	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PszF2a_RS03555	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PszF2a_RS03560	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PszF2a_RS03565	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PszF2a_RS03570	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PszF2a_RS03580	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PszF2a_RS03585	COG1841	ribosomal large subunit assembly
PszF2a_RS03590	COG0200	Binds to the 23S rRNA
PszF2a_RS03600	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PszF2a_RS03605	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PszF2a_RS03610	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PszF2a_RS03615	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PszF2a_RS03620	COG0202	RNA polymerase activity
PszF2a_RS03625	COG0203	ribosomal protein L17
PszF2a_RS03640	COG2814	Major facilitator Superfamily
PszF2a_RS03660	COG3047	cAMP biosynthetic process
PszF2a_RS03670	COG0811	peptide transport
PszF2a_RS03675	COG0811	peptide transport
PszF2a_RS03680	COG0848	biopolymer transport protein
PszF2a_RS03705	COG4181	ATPase activity
PszF2a_RS03720	COG3118	belongs to the thioredoxin family
PszF2a_RS03725	COG2391	methyltransferase activity
PszF2a_RS03730	COG0425	Belongs to the sulfur carrier protein TusA family
PszF2a_RS03740	COG2264	protein methyltransferase activity
PszF2a_RS03755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PszF2a_RS03755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PszF2a_RS03770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PszF2a_RS03775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PszF2a_RS03785	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PszF2a_RS03790	COG3577	Aspartyl protease
PszF2a_RS03795	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PszF2a_RS03810	COG4206	TonB-dependent receptor
PszF2a_RS03820	COG0420	3'-5' exonuclease activity
PszF2a_RS03880	COG1040	competence protein
PszF2a_RS03885	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PszF2a_RS03890	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS03895	COG2610	gluconate transmembrane transporter activity
PszF2a_RS03900	COG2031	fatty acid transporter
PszF2a_RS03910	COG1522	sequence-specific DNA binding
PszF2a_RS03925	COG0733	neurotransmitter:sodium symporter activity
PszF2a_RS03935	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PszF2a_RS03945	COG0625	glutathione transferase activity
PszF2a_RS03950	COG0733	neurotransmitter:sodium symporter activity
PszF2a_RS03970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PszF2a_RS03970	COG4651	solute:proton antiporter activity
PszF2a_RS03975	COG0513	Belongs to the DEAD box helicase family
PszF2a_RS04005	COG0123	including yeast histone deacetylase and acetoin utilization protein
PszF2a_RS04015	COG1946	Acyl-CoA thioesterase
PszF2a_RS04025	COG2321	neutral zinc metallopeptidase
PszF2a_RS04050	COG2197	response regulator
PszF2a_RS04055	COG3850	Histidine kinase
PszF2a_RS04060	COG2223	nitrite transmembrane transporter activity
PszF2a_RS04070	COG2223	nitrite transmembrane transporter activity
PszF2a_RS04075	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PszF2a_RS04080	COG1140	nitrate reductase beta subunit
PszF2a_RS04085	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PszF2a_RS04090	COG2181	nitrate reductase activity
PszF2a_RS04105	COG0521	Mo-molybdopterin cofactor biosynthetic process
PszF2a_RS04115	COG3038	cytochrome b561
PszF2a_RS04165	COG0642	Histidine kinase
PszF2a_RS04175	COG3642	lipopolysaccharide core region biosynthetic process
PszF2a_RS04185	COG1368	sulfuric ester hydrolase activity
PszF2a_RS04190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PszF2a_RS04195	COG2252	PERMEase
PszF2a_RS04205	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PszF2a_RS04205	COG3608	succinylglutamate desuccinylase aspartoacylase
PszF2a_RS04210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PszF2a_RS04215	COG2080	2 iron, 2 sulfur cluster binding
PszF2a_RS04220	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PszF2a_RS04225	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PszF2a_RS04250	COG0789	Transcriptional regulator
PszF2a_RS04255	COG2813	Specifically methylates the guanine in position
PszF2a_RS04290	COG0488	(ABC) transporter
PszF2a_RS04295	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PszF2a_RS04300	COG2020	methyltransferase activity
PszF2a_RS04320	COG2841	Protein conserved in bacteria
PszF2a_RS04325	COG1970	mechanosensitive ion channel activity
PszF2a_RS04335	COG1067	ATP-dependent peptidase activity
PszF2a_RS04345	COG2862	Uncharacterized protein family, UPF0114
PszF2a_RS04355	COG3046	protein related to deoxyribodipyrimidine photolyase
PszF2a_RS04365	COG0545	Peptidyl-prolyl cis-trans isomerase
PszF2a_RS04375	COG0142	geranyltranstransferase activity
PszF2a_RS04380	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PszF2a_RS04385	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PszF2a_RS04390	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PszF2a_RS04395	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PszF2a_RS04400	COG3045	CreA protein
PszF2a_RS04405	COG0268	Binds directly to 16S ribosomal RNA
PszF2a_RS04410	COG0728	peptidoglycan biosynthetic process
PszF2a_RS04415	COG0196	riboflavin kinase activity
PszF2a_RS04420	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PszF2a_RS04425	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PszF2a_RS04430	COG1047	Peptidyl-prolyl cis-trans
PszF2a_RS04435	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PszF2a_RS04480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PszF2a_RS04485	COG0023	Translation Initiation Factor
PszF2a_RS04500	COG0534	Mate efflux family protein
PszF2a_RS04530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PszF2a_RS04545	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PszF2a_RS04545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PszF2a_RS04550	COG1105	Belongs to the carbohydrate kinase PfkB family
PszF2a_RS04555	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PszF2a_RS04555	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PszF2a_RS04555	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PszF2a_RS04560	COG4993	Dehydrogenase
PszF2a_RS04565	COG2852	Protein conserved in bacteria
PszF2a_RS04575	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PszF2a_RS04580	COG0019	diaminopimelate decarboxylase activity
PszF2a_RS04590	COG3128	pkhd-type hydroxylase
PszF2a_RS04595	COG4774	siderophore transport
PszF2a_RS04600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PszF2a_RS04620	COG4771	TonB-dependent receptor
PszF2a_RS04635	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PszF2a_RS04645	COG0739	heme binding
PszF2a_RS04660	COG0530	calcium, potassium:sodium antiporter activity
PszF2a_RS04675	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PszF2a_RS04685	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PszF2a_RS04690	COG1077	Cell shape determining protein MreB Mrl
PszF2a_RS04695	COG1792	Involved in formation and maintenance of cell shape
PszF2a_RS04715	COG1530	ribonuclease E activity
PszF2a_RS04725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PszF2a_RS04730	COG0312	modulator of DNA gyrase
PszF2a_RS04740	COG0312	modulator of DNA gyrase
PszF2a_RS04745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PszF2a_RS04750	COG1660	Displays ATPase and GTPase activities
PszF2a_RS04765	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PszF2a_RS04770	COG1137	ATPase activity
PszF2a_RS04785	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PszF2a_RS04795	COG1127	ABC transporter
PszF2a_RS04800	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PszF2a_RS04805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PszF2a_RS04830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PszF2a_RS04835	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PszF2a_RS04845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PszF2a_RS04850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PszF2a_RS04860	COG0175	sulfate reduction
PszF2a_RS04870	COG1131	(ABC) transporter
PszF2a_RS04905	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PszF2a_RS04910	COG0237	dephospho-CoA kinase activity
PszF2a_RS04925	COG0667	Aldo Keto reductase
PszF2a_RS04930	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PszF2a_RS04935	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PszF2a_RS04940	COG0723	plastoquinol--plastocyanin reductase activity
PszF2a_RS04945	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PszF2a_RS04950	COG2857	Cytochrome c1
PszF2a_RS04955	COG0625	glutathione transferase activity
PszF2a_RS04960	COG2969	positive regulation of protein catabolic process
PszF2a_RS04965	COG2823	Periplasmic or secreted lipoprotein
PszF2a_RS04970	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PszF2a_RS04975	COG0792	nuclease activity
PszF2a_RS05000	COG0275	rRNA processing
PszF2a_RS05015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PszF2a_RS05020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PszF2a_RS05025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PszF2a_RS05030	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PszF2a_RS05035	COG0772	Belongs to the SEDS family
PszF2a_RS05040	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PszF2a_RS05045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PszF2a_RS05050	COG1181	Belongs to the D-alanine--D-alanine ligase family
PszF2a_RS05095	COG1285	pathogenesis
PszF2a_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS05125	COG0659	secondary active sulfate transmembrane transporter activity
PszF2a_RS05180	COG0840	transmembrane signaling receptor activity
PszF2a_RS05185	COG0501	Belongs to the peptidase M48B family
PszF2a_RS05195	COG2119	membrane
PszF2a_RS05200	COG2813	Specifically methylates the guanine in position
PszF2a_RS05205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PszF2a_RS05210	COG1280	lysine exporter protein (LysE YggA)
PszF2a_RS05215	COG0318	PFAM AMP-dependent synthetase and ligase
PszF2a_RS05220	COG0784	Response regulator, receiver
PszF2a_RS05220	COG4191	Histidine kinase
PszF2a_RS05225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PszF2a_RS05230	COG2885	chlorophyll binding
PszF2a_RS05235	COG0784	Response regulator, receiver
PszF2a_RS05235	COG2205	protein histidine kinase activity
PszF2a_RS05245	COG0204	Acyl-transferase
PszF2a_RS05255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PszF2a_RS05265	COG0386	Belongs to the glutathione peroxidase family
PszF2a_RS05270	COG1309	transcriptional regulator
PszF2a_RS05280	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
PszF2a_RS05295	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PszF2a_RS05300	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS05340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PszF2a_RS05345	COG0693	protein deglycase activity
PszF2a_RS05350	COG4628	conserved protein (DUF2132)
PszF2a_RS05370	COG0469	pyruvate kinase activity
PszF2a_RS05395	COG0714	Associated with various cellular activities
PszF2a_RS05420	COG2925	Exonuclease
PszF2a_RS05430	COG0788	formyltetrahydrofolate deformylase activity
PszF2a_RS05440	COG0433	COG0433 Predicted ATPase
PszF2a_RS05455	COG3022	response to hydroperoxide
PszF2a_RS05465	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PszF2a_RS05470	COG0315	cyclic pyranopterin monophosphate synthase activity
PszF2a_RS05475	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PszF2a_RS05495	COG0400	carboxylic ester hydrolase activity
PszF2a_RS05500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PszF2a_RS05505	COG4597	amino acid ABC transporter
PszF2a_RS05510	COG0765	amino acid transport
PszF2a_RS05515	COG1126	abc transporter atp-binding protein
PszF2a_RS05520	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PszF2a_RS05520	COG0047	phosphoribosylformylglycinamidine synthase activity
PszF2a_RS05530	COG3034	peptidoglycan biosynthetic process
PszF2a_RS05555	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PszF2a_RS05560	COG4536	flavin adenine dinucleotide binding
PszF2a_RS05565	COG4137	Cytochrome C assembly protein
PszF2a_RS05570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PszF2a_RS05575	COG0228	four-way junction DNA binding
PszF2a_RS05580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PszF2a_RS05585	COG0336	Belongs to the RNA methyltransferase TrmD family
PszF2a_RS05590	COG0335	large ribosomal subunit rRNA binding
PszF2a_RS05605	COG3791	Glutathione-dependent formaldehyde-activating
PszF2a_RS05620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PszF2a_RS05625	COG0418	dihydroorotase activity
PszF2a_RS05635	COG0137	argininosuccinate synthase activity
PszF2a_RS05640	COG0346	lactoylglutathione lyase activity
PszF2a_RS05650	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PszF2a_RS05660	COG4659	FMN binding
PszF2a_RS05665	COG4658	electron transport chain
PszF2a_RS05675	COG2878	Part of a membrane complex involved in electron transport
PszF2a_RS05680	COG4657	Part of a membrane complex involved in electron transport
PszF2a_RS05695	COG1024	Enoyl-CoA hydratase
PszF2a_RS05705	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PszF2a_RS05720	COG0354	folic acid binding
PszF2a_RS05760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PszF2a_RS05765	COG0481	GTPase activity
PszF2a_RS05780	COG0571	ribonuclease III activity
PszF2a_RS05790	COG1381	Involved in DNA repair and RecF pathway recombination
PszF2a_RS05795	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PszF2a_RS05805	COG0583	DNA-binding transcription factor activity
PszF2a_RS05815	COG0500	methyltransferase
PszF2a_RS05820	COG2226	methyltransferase
PszF2a_RS05830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PszF2a_RS05845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PszF2a_RS05860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PszF2a_RS05870	COG0583	DNA-binding transcription factor activity
PszF2a_RS05875	COG3485	protocatechuate 3,4-dioxygenase
PszF2a_RS05880	COG3485	protocatechuate 3,4-dioxygenase
PszF2a_RS05885	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PszF2a_RS05890	COG0679	Auxin Efflux Carrier
PszF2a_RS05895	COG1414	Transcriptional regulator
PszF2a_RS05900	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PszF2a_RS05905	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PszF2a_RS05920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PszF2a_RS05925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PszF2a_RS05930	COG3609	addiction module antidote protein, CC2985 family
PszF2a_RS06010	COG4128	Pfam Zonular occludens toxin
PszF2a_RS06040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PszF2a_RS06040	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PszF2a_RS06045	COG0489	protein tyrosine kinase activity
PszF2a_RS06050	COG1278	Cold shock
PszF2a_RS06055	COG0717	Belongs to the dCTP deaminase family
PszF2a_RS06060	COG3005	denitrification pathway
PszF2a_RS06070	COG0243	molybdopterin cofactor binding
PszF2a_RS06080	COG4459	periplasmic nitrate reductase
PszF2a_RS06085	COG2814	Major facilitator Superfamily
PszF2a_RS06110	COG0037	tRNA processing
PszF2a_RS06115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PszF2a_RS06120	COG2818	Glycosylase
PszF2a_RS06145	COG1294	oxidase, subunit
PszF2a_RS06150	COG4890	Cyd operon protein YbgT
PszF2a_RS06165	COG0791	NLP P60 protein
PszF2a_RS06170	COG0791	NLP P60 protein
PszF2a_RS06185	COG4206	TonB-dependent receptor
PszF2a_RS06200	COG1797	cobyrinic acid a,c-diamide synthase activity
PszF2a_RS06205	COG0778	Nitroreductase
PszF2a_RS06215	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PszF2a_RS06225	COG1492	cobalamin metabolic process
PszF2a_RS06245	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PszF2a_RS06255	COG0251	oxidation-reduction process
PszF2a_RS06285	COG2067	long-chain fatty acid transport protein
PszF2a_RS06300	COG3100	YcgL domain-containing protein
PszF2a_RS06310	COG2983	Belongs to the UPF0260 family
PszF2a_RS06325	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PszF2a_RS06330	COG0527	aspartate kinase activity
PszF2a_RS06335	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PszF2a_RS06360	COG2239	Acts as a magnesium transporter
PszF2a_RS06365	COG3630	sodium ion export across plasma membrane
PszF2a_RS06370	COG0511	ligase activity, forming carbon-carbon bonds
PszF2a_RS06370	COG5016	pyruvate
PszF2a_RS06375	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
PszF2a_RS06405	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PszF2a_RS06425	COG0784	Response regulator, receiver
PszF2a_RS06425	COG0835	chemotaxis
PszF2a_RS06430	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PszF2a_RS06435	COG1815	bacterial-type flagellum-dependent cell motility
PszF2a_RS06455	COG4787	bacterial-type flagellum-dependent cell motility
PszF2a_RS06460	COG4786	Flagellar basal body rod
PszF2a_RS06465	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PszF2a_RS06470	COG1706	bacterial-type flagellum-dependent cell motility
PszF2a_RS06480	COG1256	bacterial-type flagellum assembly
PszF2a_RS06490	COG1555	photosystem II stabilization
PszF2a_RS06515	COG2200	EAL domain
PszF2a_RS06530	COG1362	aminopeptidase activity
PszF2a_RS06540	COG0564	pseudouridine synthase activity
PszF2a_RS06545	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PszF2a_RS06550	COG2894	cell division
PszF2a_RS06555	COG0850	regulation of cytokinetic process
PszF2a_RS06560	COG1560	Kdo2-lipid A biosynthetic process
PszF2a_RS06570	COG2853	Lipoprotein
PszF2a_RS06585	COG3162	membrane
PszF2a_RS06590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PszF2a_RS06610	COG3089	Belongs to the UPF0270 family
PszF2a_RS06620	COG1363	Peptidase, m42
PszF2a_RS06625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PszF2a_RS06625	COG0189	ligase activity
PszF2a_RS06630	COG0367	asparagine synthase
PszF2a_RS06640	COG1404	Belongs to the peptidase S8 family
PszF2a_RS06640	COG4935	Belongs to the peptidase S8 family
PszF2a_RS06650	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PszF2a_RS06660	COG4221	oxidoreductase activity
PszF2a_RS06670	COG1201	RNA secondary structure unwinding
PszF2a_RS06710	COG2133	pyrroloquinoline quinone binding
PszF2a_RS06715	COG4993	Dehydrogenase
PszF2a_RS06720	COG2996	Protein conserved in bacteria
PszF2a_RS06735	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PszF2a_RS06770	COG3292	Two component regulator propeller
PszF2a_RS06770	COG2205	protein histidine kinase activity
PszF2a_RS06770	COG0745	RESPONSE REGULATOR receiver
PszF2a_RS06805	COG0784	Response regulator, receiver
PszF2a_RS06805	COG2198	Histidine kinase
PszF2a_RS06805	COG5002	protein histidine kinase activity
PszF2a_RS06845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PszF2a_RS06855	COG1295	ribonuclease BN
PszF2a_RS06860	COG0438	transferase activity, transferring glycosyl groups
PszF2a_RS06880	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PszF2a_RS06885	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PszF2a_RS06890	COG0582	viral genome integration into host DNA
PszF2a_RS07005	COG0616	signal peptide processing
PszF2a_RS07095	COG3179	chitinase
PszF2a_RS07110	COG2135	peptidase activity
PszF2a_RS07120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PszF2a_RS07130	COG1546	Belongs to the CinA family
PszF2a_RS07135	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PszF2a_RS07140	COG2137	regulation of response to DNA damage stimulus
PszF2a_RS07150	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PszF2a_RS07155	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PszF2a_RS07165	COG3148	PFAM DTW domain containing protein
PszF2a_RS07170	COG0697	spore germination
PszF2a_RS07180	COG0583	DNA-binding transcription factor activity
PszF2a_RS07190	COG3012	SEC-C Motif Domain Protein
PszF2a_RS07210	COG1199	ATP-dependent helicase activity
PszF2a_RS07215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PszF2a_RS07225	COG0259	pyridoxamine-phosphate oxidase activity
PszF2a_RS07240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PszF2a_RS07240	COG2111	Na H antiporter
PszF2a_RS07245	COG1006	Multisubunit Na H antiporter MnhC subunit
PszF2a_RS07250	COG0651	ATP synthesis coupled electron transport
PszF2a_RS07255	COG1863	multisubunit Na H antiporter MnhE subunit
PszF2a_RS07260	COG2212	antiporter activity
PszF2a_RS07265	COG1320	monovalent cation:proton antiporter activity
PszF2a_RS07270	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PszF2a_RS07275	COG0024	Methionine aminopeptidase
PszF2a_RS07280	COG0052	Belongs to the universal ribosomal protein uS2 family
PszF2a_RS07285	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PszF2a_RS07290	COG0528	UMP kinase activity
PszF2a_RS07295	COG0233	cytoplasmic translational termination
PszF2a_RS07300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PszF2a_RS07310	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PszF2a_RS07320	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PszF2a_RS07330	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PszF2a_RS07335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PszF2a_RS07340	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PszF2a_RS07345	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PszF2a_RS07350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PszF2a_RS07360	COG0825	malonyl-CoA metabolic process
PszF2a_RS07365	COG0037	tRNA processing
PszF2a_RS07370	COG0504	CTP synthase activity
PszF2a_RS07375	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PszF2a_RS07390	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PszF2a_RS07405	COG0583	DNA-binding transcription factor activity
PszF2a_RS07415	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PszF2a_RS07420	COG1902	pentaerythritol trinitrate reductase activity
PszF2a_RS07430	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PszF2a_RS07435	COG0585	pseudouridine synthase activity
PszF2a_RS07440	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PszF2a_RS07445	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PszF2a_RS07500	COG0589	response to stress
PszF2a_RS07510	COG0217	transcriptional regulatory protein
PszF2a_RS07520	COG2258	MOSC domain
PszF2a_RS07535	COG0004	ammonium transporteR
PszF2a_RS07540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PszF2a_RS07585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PszF2a_RS07590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PszF2a_RS07600	COG1283	sodium-dependent phosphate transmembrane transporter activity
PszF2a_RS07615	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PszF2a_RS07640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PszF2a_RS07660	COG0826	peptidase U32
PszF2a_RS07690	COG0840	transmembrane signaling receptor activity
PszF2a_RS07705	COG2188	Transcriptional regulator
PszF2a_RS07710	COG0789	Transcriptional regulator
PszF2a_RS07720	COG3135	benzoate transporter
PszF2a_RS07725	COG1677	Flagellar hook-basal body complex protein FliE
PszF2a_RS07760	COG0745	RESPONSE REGULATOR receiver
PszF2a_RS07800	COG1987	bacterial-type flagellum assembly
PszF2a_RS07815	COG2032	superoxide dismutase activity
PszF2a_RS07845	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PszF2a_RS07850	COG0784	Response regulator, receiver
PszF2a_RS07850	COG2198	Histidine kinase
PszF2a_RS07850	COG0643	Histidine kinase
PszF2a_RS07855	COG2201	protein-glutamate methylesterase activity
PszF2a_RS07860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PszF2a_RS07865	COG1360	Flagellar Motor Protein
PszF2a_RS07870	COG1192	Involved in chromosome partitioning
PszF2a_RS07880	COG0835	chemotaxis
PszF2a_RS07895	COG2257	FlhB HrpN YscU SpaS Family
PszF2a_RS07925	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PszF2a_RS07975	COG0500	methyltransferase
PszF2a_RS07985	COG0501	Belongs to the peptidase M48B family
PszF2a_RS07995	COG0436	Aminotransferase
PszF2a_RS08000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PszF2a_RS08005	COG0386	Belongs to the glutathione peroxidase family
PszF2a_RS08040	COG0640	Transcriptional regulator
PszF2a_RS08070	COG3453	Protein conserved in bacteria
PszF2a_RS08070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PszF2a_RS08080	COG1136	(ABC) transporter
PszF2a_RS08085	COG4591	ABC-type transport system involved in lipoprotein release permease component
PszF2a_RS08110	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
PszF2a_RS08125	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PszF2a_RS08130	COG0471	metal ion transport
PszF2a_RS08135	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PszF2a_RS08140	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PszF2a_RS08145	COG0840	transmembrane signaling receptor activity
PszF2a_RS08155	COG0776	regulation of translation
PszF2a_RS08170	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PszF2a_RS08175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PszF2a_RS08190	COG1216	Glycosyl transferase, family 2
PszF2a_RS08200	COG0438	transferase activity, transferring glycosyl groups
PszF2a_RS08210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PszF2a_RS08225	COG2977	Belongs to the P-Pant transferase superfamily
PszF2a_RS08235	COG0183	Belongs to the thiolase family
PszF2a_RS08275	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PszF2a_RS08280	COG3206	protein involved in exopolysaccharide biosynthesis
PszF2a_RS08280	COG0489	protein tyrosine kinase activity
PszF2a_RS08285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PszF2a_RS08290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PszF2a_RS08300	COG3437	response regulator, receiver
PszF2a_RS08305	COG3217	Mosc domain protein beta barrel domain protein
PszF2a_RS08305	COG0633	Ferredoxin
PszF2a_RS08310	COG0741	lytic transglycosylase activity
PszF2a_RS08315	COG0488	(ABC) transporter
PszF2a_RS08325	COG0589	response to stress
PszF2a_RS08335	COG0121	glutamine amidotransferase
PszF2a_RS08355	COG0542	response to heat
PszF2a_RS08365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PszF2a_RS08375	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PszF2a_RS08390	COG2832	Protein of unknown function (DUF454)
PszF2a_RS08400	COG0514	ATP-dependent DNA helicase (RecQ)
PszF2a_RS08410	COG1752	Esterase of the alpha-beta hydrolase superfamily
PszF2a_RS08425	COG2207	Transcriptional regulator
PszF2a_RS08445	COG2354	Protein conserved in bacteria
PszF2a_RS08450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PszF2a_RS08455	COG0727	PFAM Uncharacterised protein family (UPF0153)
PszF2a_RS08460	COG0778	Nitroreductase
PszF2a_RS08475	COG0745	RESPONSE REGULATOR receiver
PszF2a_RS08485	COG2350	Protein conserved in bacteria
PszF2a_RS08490	COG0613	PHP domain protein
PszF2a_RS08495	COG0009	L-threonylcarbamoyladenylate synthase
PszF2a_RS08500	COG0180	Tryptophanyl-tRNA synthetase
PszF2a_RS08510	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PszF2a_RS08535	COG1653	transport
PszF2a_RS08540	COG1175	transmembrane transport
PszF2a_RS08545	COG0395	ABC-type sugar transport system, permease component
PszF2a_RS08550	COG3842	ATPase activity
PszF2a_RS08555	COG4580	involved in the transport of maltose and maltodextrins
PszF2a_RS08570	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PszF2a_RS08585	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PszF2a_RS08610	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PszF2a_RS08625	COG0730	response to heat
PszF2a_RS08640	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PszF2a_RS08645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PszF2a_RS08665	COG0308	aminopeptidase N
PszF2a_RS08685	COG0243	molybdopterin cofactor binding
PszF2a_RS08690	COG2146	nitrite reductase [NAD(P)H] activity
PszF2a_RS08695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PszF2a_RS08705	COG2815	serine threonine protein kinase
PszF2a_RS08705	COG0515	serine threonine protein kinase
PszF2a_RS08710	COG2223	nitrite transmembrane transporter activity
PszF2a_RS08730	COG3707	response regulator
PszF2a_RS08735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PszF2a_RS08745	COG2304	oxidoreductase activity
PszF2a_RS08765	COG0714	Associated with various cellular activities
PszF2a_RS08785	COG0167	dihydroorotate dehydrogenase activity
PszF2a_RS08790	COG3130	regulation of translation
PszF2a_RS08795	COG0116	Belongs to the methyltransferase superfamily
PszF2a_RS08795	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PszF2a_RS08800	COG2027	D-alanyl-D-alanine carboxypeptidase
PszF2a_RS08805	COG3171	Protein conserved in bacteria
PszF2a_RS08880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PszF2a_RS08890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PszF2a_RS08900	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PszF2a_RS08905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PszF2a_RS08910	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PszF2a_RS08915	COG0072	phenylalanine-tRNA ligase activity
PszF2a_RS08920	COG0776	regulation of translation
PszF2a_RS08955	COG2948	multi-organism process
PszF2a_RS08980	COG3451	type IV secretory pathway VirB4
PszF2a_RS08995	COG4962	Type ii secretion system protein e
PszF2a_RS09015	COG1696	Membrane protein involved in D-alanine export
PszF2a_RS09025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PszF2a_RS09035	COG0659	secondary active sulfate transmembrane transporter activity
PszF2a_RS09055	COG1429	ligase activity, forming nitrogen-metal bonds
PszF2a_RS09060	COG4771	TonB-dependent receptor
PszF2a_RS09075	COG0583	DNA-binding transcription factor activity
PszF2a_RS09085	COG0367	asparagine synthase
PszF2a_RS09100	COG0156	8-amino-7-oxononanoate synthase activity
PszF2a_RS09105	COG3250	beta-galactosidase activity
PszF2a_RS09145	COG1392	Phosphate transport regulator
PszF2a_RS09155	COG3550	peptidyl-serine autophosphorylation
PszF2a_RS09185	COG0745	RESPONSE REGULATOR receiver
PszF2a_RS09190	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PszF2a_RS09195	COG2135	peptidase activity
PszF2a_RS09200	COG0587	DNA-directed DNA polymerase activity
PszF2a_RS09205	COG3300	MHYT domain
PszF2a_RS09205	COG5001	Diguanylate cyclase
PszF2a_RS09235	COG0583	DNA-binding transcription factor activity
PszF2a_RS09275	COG1132	(ABC) transporter
PszF2a_RS09280	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PszF2a_RS09290	COG1335	isochorismatase
PszF2a_RS09310	COG2197	response regulator
PszF2a_RS09355	COG0583	DNA-binding transcription factor activity
PszF2a_RS09365	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
PszF2a_RS09370	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PszF2a_RS09380	COG0471	metal ion transport
PszF2a_RS09385	COG1929	Belongs to the glycerate kinase type-1 family
PszF2a_RS09475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PszF2a_RS09480	COG4774	siderophore transport
PszF2a_RS09500	COG3550	peptidyl-serine autophosphorylation
PszF2a_RS09530	COG1629	transport
PszF2a_RS09530	COG4774	siderophore transport
PszF2a_RS09545	COG3284	Transcriptional regulator
PszF2a_RS09550	COG1012	belongs to the aldehyde dehydrogenase family
PszF2a_RS09560	COG4772	TonB-dependent receptor
PszF2a_RS09590	COG4771	TonB-dependent receptor
PszF2a_RS09615	COG1253	flavin adenine dinucleotide binding
PszF2a_RS09630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PszF2a_RS09635	COG2003	Belongs to the UPF0758 family
PszF2a_RS09645	COG5489	Protein of unknown function (DUF736)
PszF2a_RS09655	COG2010	Cytochrome c
PszF2a_RS09660	COG3256	nitric oxide reductase
PszF2a_RS09665	COG0714	Associated with various cellular activities
PszF2a_RS09670	COG4548	von Willebrand factor, type A
PszF2a_RS09685	COG0745	RESPONSE REGULATOR receiver
PszF2a_RS09705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PszF2a_RS09705	COG0475	glutathione-regulated potassium exporter activity
PszF2a_RS09710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PszF2a_RS09715	COG1126	abc transporter atp-binding protein
PszF2a_RS09720	COG0765	amino acid transport
PszF2a_RS09725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PszF2a_RS09745	COG0587	DNA-directed DNA polymerase activity
PszF2a_RS09760	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PszF2a_RS09770	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PszF2a_RS09775	COG0077	Prephenate dehydratase
PszF2a_RS09775	COG1605	Chorismate mutase
PszF2a_RS09785	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PszF2a_RS09790	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PszF2a_RS09805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PszF2a_RS09810	COG0625	glutathione transferase activity
PszF2a_RS09820	COG2840	Smr protein MutS2
PszF2a_RS09845	COG0800	Aldolase
PszF2a_RS09855	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS09860	COG0546	phosphoglycolate phosphatase activity
PszF2a_RS09865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PszF2a_RS09870	COG0402	S-adenosylhomocysteine deaminase activity
PszF2a_RS09900	COG0720	synthase
PszF2a_RS09905	COG2056	Na+-H+ antiporter family
PszF2a_RS09910	COG0628	permease
PszF2a_RS09935	COG2153	protein acetylation
PszF2a_RS09940	COG2850	peptidyl-arginine hydroxylation
PszF2a_RS09950	COG2915	High frequency lysogenization protein hflD homolog
PszF2a_RS09955	COG0482	sulfurtransferase activity
PszF2a_RS09980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PszF2a_RS09985	COG0542	response to heat
PszF2a_RS09990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PszF2a_RS09995	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PszF2a_RS10000	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PszF2a_RS10005	COG0492	ferredoxin-NADP+ reductase activity
PszF2a_RS10015	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PszF2a_RS10020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PszF2a_RS10025	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PszF2a_RS10030	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PszF2a_RS10035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PszF2a_RS10035	COG1648	precorrin-2 dehydrogenase activity
PszF2a_RS10055	COG1131	(ABC) transporter
PszF2a_RS10075	COG0840	transmembrane signaling receptor activity
PszF2a_RS10135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PszF2a_RS10155	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS10165	COG4172	Belongs to the ABC transporter superfamily
PszF2a_RS10170	COG4239	(ABC) transporter, permease
PszF2a_RS10175	COG4174	ABC transporter (Permease)
PszF2a_RS10185	COG4166	transmembrane transport
PszF2a_RS10195	COG1388	LysM domain
PszF2a_RS10195	COG0741	lytic transglycosylase activity
PszF2a_RS10200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PszF2a_RS10210	COG0328	RNA-DNA hybrid ribonuclease activity
PszF2a_RS10215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PszF2a_RS10225	COG1024	Enoyl-CoA hydratase
PszF2a_RS10235	COG2816	NAD+ diphosphatase activity
PszF2a_RS10250	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS10270	COG0616	signal peptide processing
PszF2a_RS10275	COG0604	alcohol dehydrogenase
PszF2a_RS10295	COG0071	Belongs to the small heat shock protein (HSP20) family
PszF2a_RS10310	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PszF2a_RS10315	COG2223	nitrite transmembrane transporter activity
PszF2a_RS10340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PszF2a_RS10340	COG2755	lipolytic protein G-D-S-L family
PszF2a_RS10360	COG0316	Belongs to the HesB IscA family
PszF2a_RS10360	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PszF2a_RS10365	COG2201	protein-glutamate methylesterase activity
PszF2a_RS10370	COG3706	GGDEF domain
PszF2a_RS10385	COG2323	membrane
PszF2a_RS10400	COG0840	transmembrane signaling receptor activity
PszF2a_RS10405	COG1968	undecaprenyl-diphosphatase activity
PszF2a_RS10410	COG0488	(ABC) transporter
PszF2a_RS10435	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PszF2a_RS10440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PszF2a_RS10445	COG3265	gluconokinase activity
PszF2a_RS10450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PszF2a_RS10455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PszF2a_RS10460	COG1609	Transcriptional regulator
PszF2a_RS10475	COG1070	Carbohydrate kinase
PszF2a_RS10495	COG1175	transmembrane transport
PszF2a_RS10530	COG0729	surface antigen
PszF2a_RS10535	COG2911	Protein conserved in bacteria
PszF2a_RS10540	COG1115	amino acid carrier protein
PszF2a_RS10555	COG0728	peptidoglycan biosynthetic process
PszF2a_RS10565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PszF2a_RS10615	COG0604	alcohol dehydrogenase
PszF2a_RS10615	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS10615	COG3321	synthase
PszF2a_RS10620	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS10640	COG0437	4 iron, 4 sulfur cluster binding
PszF2a_RS10645	COG2864	formate dehydrogenase
PszF2a_RS10665	COG0366	Alpha amylase catalytic
PszF2a_RS10670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PszF2a_RS10675	COG0392	lysyltransferase activity
PszF2a_RS10680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PszF2a_RS10685	COG3568	Endonuclease Exonuclease Phosphatase
PszF2a_RS10700	COG0583	DNA-binding transcription factor activity
PszF2a_RS10705	COG3384	dioxygenase
PszF2a_RS10710	COG3038	cytochrome b561
PszF2a_RS10715	COG0739	heme binding
PszF2a_RS10740	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PszF2a_RS10745	COG0297	glycogen (starch) synthase activity
PszF2a_RS10750	COG1058	Belongs to the CinA family
PszF2a_RS10750	COG1546	Belongs to the CinA family
PszF2a_RS10755	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PszF2a_RS10755	COG3264	Mechanosensitive ion channel
PszF2a_RS10760	COG3685	Protein conserved in bacteria
PszF2a_RS10785	COG0028	Belongs to the TPP enzyme family
PszF2a_RS10790	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS10795	COG0723	plastoquinol--plastocyanin reductase activity
PszF2a_RS10810	COG0583	DNA-binding transcription factor activity
PszF2a_RS10820	COG1566	PFAM secretion protein HlyD family protein
PszF2a_RS10845	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PszF2a_RS10895	COG5642	Protein of unknown function (DUF2384)
PszF2a_RS10920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PszF2a_RS10925	COG1742	UPF0060 membrane protein
PszF2a_RS10935	COG0431	NADPH-dependent FMN reductase
PszF2a_RS10940	COG0640	Transcriptional regulator
PszF2a_RS10945	COG2072	flavoprotein involved in K transport
PszF2a_RS10950	COG0798	PFAM Bile acid sodium symporter
PszF2a_RS11005	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PszF2a_RS11010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PszF2a_RS11025	COG5002	protein histidine kinase activity
PszF2a_RS11040	COG0535	radical SAM domain protein
PszF2a_RS11050	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
PszF2a_RS11055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PszF2a_RS11095	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PszF2a_RS11100	COG0167	dihydroorotate dehydrogenase activity
PszF2a_RS11105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PszF2a_RS11115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PszF2a_RS11120	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PszF2a_RS11130	COG0544	peptidyl-prolyl cis-trans isomerase activity
PszF2a_RS11140	COG2186	Transcriptional regulator
PszF2a_RS11160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PszF2a_RS11165	COG0215	cysteine-tRNA ligase activity
PszF2a_RS11170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PszF2a_RS11175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PszF2a_RS11180	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PszF2a_RS11215	COG0668	transmembrane transport
PszF2a_RS11230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PszF2a_RS11240	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PszF2a_RS11255	COG0372	Belongs to the citrate synthase family
PszF2a_RS11265	COG1802	Transcriptional regulator
PszF2a_RS11290	COG0560	Phosphoserine phosphatase
PszF2a_RS11305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PszF2a_RS11310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PszF2a_RS11325	COG1376	ErfK ybiS ycfS ynhG family protein
PszF2a_RS11340	COG4181	ATPase activity
PszF2a_RS11345	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PszF2a_RS11365	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PszF2a_RS11370	COG0084	hydrolase, TatD family'
PszF2a_RS11385	COG3842	ATPase activity
PszF2a_RS11390	COG3665	Urea carboxylase-associated protein
PszF2a_RS11400	COG4770	biotin carboxylase activity
PszF2a_RS11415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PszF2a_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS11445	COG1335	isochorismatase
PszF2a_RS11455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PszF2a_RS11460	COG1116	anion transmembrane transporter activity
PszF2a_RS11465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PszF2a_RS11470	COG0174	glutamine synthetase
PszF2a_RS11495	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PszF2a_RS11495	COG2755	lipolytic protein G-D-S-L family
PszF2a_RS11550	COG2920	part of a sulfur-relay system
PszF2a_RS11555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PszF2a_RS11560	COG0435	Glutathione S-transferase
PszF2a_RS11565	COG0784	Response regulator, receiver
PszF2a_RS11565	COG2205	protein histidine kinase activity
PszF2a_RS11580	COG1025	Belongs to the peptidase M16 family
PszF2a_RS11585	COG0789	Transcriptional regulator
PszF2a_RS11595	COG0302	gtp cyclohydrolase
PszF2a_RS11600	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PszF2a_RS11620	COG1366	Belongs to the anti-sigma-factor antagonist family
PszF2a_RS11630	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PszF2a_RS11635	COG1090	epimerase
PszF2a_RS11640	COG3272	Protein of unknown function (DUF1722)
PszF2a_RS11645	COG0789	Transcriptional regulator
PszF2a_RS11650	COG0415	Belongs to the DNA photolyase family
PszF2a_RS11660	COG4221	oxidoreductase activity
PszF2a_RS11675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PszF2a_RS11680	COG0840	transmembrane signaling receptor activity
PszF2a_RS11695	COG2146	nitrite reductase [NAD(P)H] activity
PszF2a_RS11695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PszF2a_RS11700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PszF2a_RS11700	COG2146	nitrite reductase [NAD(P)H] activity
PszF2a_RS11710	COG0515	serine threonine protein kinase
PszF2a_RS11715	COG0210	DNA helicase
PszF2a_RS11755	COG3447	MASE1 domain protein
PszF2a_RS11755	COG5001	Diguanylate cyclase
PszF2a_RS11755	COG5002	protein histidine kinase activity
PszF2a_RS11790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PszF2a_RS11795	COG4191	Histidine kinase
PszF2a_RS11795	COG0784	Response regulator, receiver
PszF2a_RS11800	COG4991	sh3 domain protein
PszF2a_RS11815	COG2207	Transcriptional regulator
PszF2a_RS11830	COG0058	SHG alpha-glucan phosphorylase activity
PszF2a_RS11835	COG0745	RESPONSE REGULATOR receiver
PszF2a_RS11840	COG2205	protein histidine kinase activity
PszF2a_RS11855	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PszF2a_RS11890	COG1024	Enoyl-CoA hydratase
PszF2a_RS11895	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS11905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PszF2a_RS11910	COG0318	PFAM AMP-dependent synthetase and ligase
PszF2a_RS11915	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS11920	COG0183	Belongs to the thiolase family
PszF2a_RS11935	COG1238	metal cluster binding
PszF2a_RS11960	COG0714	Associated with various cellular activities
PszF2a_RS11970	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PszF2a_RS11975	COG0709	Synthesizes selenophosphate from selenide and ATP
PszF2a_RS11985	COG0628	permease
PszF2a_RS12020	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PszF2a_RS12025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PszF2a_RS12035	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PszF2a_RS12065	COG0326	Molecular chaperone. Has ATPase activity
PszF2a_RS12100	COG0045	succinate-CoA ligase (ADP-forming) activity
PszF2a_RS12120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PszF2a_RS12125	COG1053	succinate dehydrogenase
PszF2a_RS12130	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PszF2a_RS12135	COG2009	succinate dehydrogenase
PszF2a_RS12150	COG3123	guanosine phosphorylase activity
PszF2a_RS12180	COG1216	Glycosyl transferase, family 2
PszF2a_RS12180	COG0438	transferase activity, transferring glycosyl groups
PszF2a_RS12190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PszF2a_RS12210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PszF2a_RS12215	COG2089	acid synthase
PszF2a_RS12225	COG1083	cytidylyl-transferase
PszF2a_RS12235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PszF2a_RS12240	COG1086	Polysaccharide biosynthesis protein
PszF2a_RS12245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PszF2a_RS12250	COG3115	cell septum assembly
PszF2a_RS12260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PszF2a_RS12265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PszF2a_RS12280	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PszF2a_RS12280	COG2010	Cytochrome c
PszF2a_RS12285	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PszF2a_RS12305	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PszF2a_RS12315	COG0840	transmembrane signaling receptor activity
PszF2a_RS12325	COG3278	Belongs to the heme-copper respiratory oxidase family
PszF2a_RS12335	COG2010	Cytochrome c
PszF2a_RS12340	COG3278	Belongs to the heme-copper respiratory oxidase family
PszF2a_RS12355	COG2010	Cytochrome c
PszF2a_RS12385	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PszF2a_RS12395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PszF2a_RS12400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PszF2a_RS12415	COG0573	inorganic phosphate transmembrane transporter activity
PszF2a_RS12430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PszF2a_RS12435	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PszF2a_RS12445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PszF2a_RS12475	COG1902	pentaerythritol trinitrate reductase activity
PszF2a_RS12475	COG0446	pyridine nucleotide-disulphide oxidoreductase
PszF2a_RS12495	COG1294	oxidase, subunit
PszF2a_RS12500	COG1271	oxidase subunit
PszF2a_RS12530	COG0655	NAD(P)H dehydrogenase (quinone) activity
PszF2a_RS12560	COG0789	Transcriptional regulator
PszF2a_RS12565	COG0477	Major facilitator Superfamily
PszF2a_RS12580	COG0254	rRNA binding
PszF2a_RS12585	COG4771	TonB-dependent receptor
PszF2a_RS12615	COG0789	Transcriptional regulator
PszF2a_RS12650	COG1286	toxin biosynthetic process
PszF2a_RS12655	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PszF2a_RS12660	COG0285	dihydrofolate synthase activity
PszF2a_RS12665	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PszF2a_RS12670	COG0135	phosphoribosylanthranilate isomerase activity
PszF2a_RS12700	COG0066	3-isopropylmalate dehydratase activity
PszF2a_RS12705	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PszF2a_RS12720	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS12780	COG0250	Participates in transcription elongation, termination and antitermination
PszF2a_RS12810	COG0297	glycogen (starch) synthase activity
PszF2a_RS12835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PszF2a_RS12840	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PszF2a_RS12845	COG1012	belongs to the aldehyde dehydrogenase family
PszF2a_RS12850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PszF2a_RS12855	COG0133	tryptophan synthase activity
PszF2a_RS12875	COG0653	protein targeting
PszF2a_RS12940	COG0183	Belongs to the thiolase family
PszF2a_RS12945	COG1024	Enoyl-CoA hydratase
PszF2a_RS12945	COG1250	3-hydroxyacyl-CoA dehydrogenase
PszF2a_RS12950	COG1770	oligopeptidase
PszF2a_RS12960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PszF2a_RS12975	COG0583	DNA-binding transcription factor activity
PszF2a_RS12980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PszF2a_RS12985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PszF2a_RS13015	COG2301	Belongs to the HpcH HpaI aldolase family
PszF2a_RS13025	COG2079	MmgE PrpD family protein
PszF2a_RS13035	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS13040	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PszF2a_RS13045	COG0583	DNA-binding transcription factor activity
PszF2a_RS13070	COG0840	transmembrane signaling receptor activity
PszF2a_RS13085	COG1054	Belongs to the UPF0176 family
PszF2a_RS13090	COG0271	Belongs to the BolA IbaG family
PszF2a_RS13100	COG0114	fumarate hydratase activity
PszF2a_RS13110	COG0784	Response regulator, receiver
PszF2a_RS13110	COG4191	Histidine kinase
PszF2a_RS13145	COG3135	benzoate transporter
PszF2a_RS13150	COG3485	protocatechuate 3,4-dioxygenase
PszF2a_RS13155	COG4829	muconolactone delta-isomerase
PszF2a_RS13160	COG4948	Mandelate Racemase Muconate Lactonizing
PszF2a_RS13165	COG2814	Major facilitator Superfamily
PszF2a_RS13200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PszF2a_RS13220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PszF2a_RS13230	COG0745	RESPONSE REGULATOR receiver
PszF2a_RS13240	COG2853	Lipoprotein
PszF2a_RS13250	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PszF2a_RS13250	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PszF2a_RS13255	COG0842	Transport permease protein
PszF2a_RS13260	COG1131	(ABC) transporter
PszF2a_RS13265	COG2988	succinylglutamate desuccinylase activity
PszF2a_RS13310	COG0668	transmembrane transport
PszF2a_RS13320	COG2205	protein histidine kinase activity
PszF2a_RS13325	COG0745	RESPONSE REGULATOR receiver
PszF2a_RS13335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PszF2a_RS13350	COG1943	Transposase
PszF2a_RS13360	COG0583	DNA-binding transcription factor activity
PszF2a_RS13365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PszF2a_RS13375	COG2226	methyltransferase
PszF2a_RS13380	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PszF2a_RS13405	COG0583	DNA-binding transcription factor activity
PszF2a_RS13430	COG2130	NADP-dependent
PszF2a_RS13445	COG5001	Diguanylate cyclase
PszF2a_RS13445	COG3300	MHYT domain
PszF2a_RS13455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PszF2a_RS13515	COG1113	amino acid transport
PszF2a_RS13520	COG0084	hydrolase, TatD family'
PszF2a_RS13535	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PszF2a_RS13540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PszF2a_RS13550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PszF2a_RS13555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PszF2a_RS13570	COG0416	fatty acid biosynthetic process
PszF2a_RS13575	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PszF2a_RS13585	COG0424	maF-like protein
PszF2a_RS13590	COG0616	signal peptide processing
PszF2a_RS13590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PszF2a_RS13605	COG1530	ribonuclease E activity
PszF2a_RS13610	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PszF2a_RS13615	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PszF2a_RS13620	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PszF2a_RS13625	COG2835	tetraacyldisaccharide 4'-kinase activity
PszF2a_RS13630	COG1663	tetraacyldisaccharide 4'-kinase activity
PszF2a_RS13640	COG0811	peptide transport
PszF2a_RS13645	COG0658	competence protein
PszF2a_RS13645	COG2333	competence protein COMEC
PszF2a_RS13660	COG1136	(ABC) transporter
PszF2a_RS13665	COG4591	ABC-type transport system involved in lipoprotein release permease component
PszF2a_RS13680	COG0584	glycerophosphoryl diester phosphodiesterase
PszF2a_RS13685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PszF2a_RS13695	COG1477	protein flavinylation
PszF2a_RS13705	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PszF2a_RS13720	COG1805	sodium ion transport
PszF2a_RS13735	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PszF2a_RS13745	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PszF2a_RS13760	COG1793	dna ligase
PszF2a_RS13765	COG1201	RNA secondary structure unwinding
PszF2a_RS13795	COG3956	TIGRFAM MazG family protein
PszF2a_RS13800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PszF2a_RS13805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PszF2a_RS13820	COG2860	membrane
PszF2a_RS13825	COG0784	Response regulator, receiver
PszF2a_RS13825	COG2205	protein histidine kinase activity
PszF2a_RS13825	COG5002	protein histidine kinase activity
PszF2a_RS13830	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PszF2a_RS13830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PszF2a_RS13850	COG0583	DNA-binding transcription factor activity
PszF2a_RS13865	COG0513	Belongs to the DEAD box helicase family
PszF2a_RS13905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PszF2a_RS13910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PszF2a_RS13915	COG2226	methyltransferase
PszF2a_RS13940	COG1131	(ABC) transporter
PszF2a_RS13970	COG2937	Belongs to the GPAT DAPAT family
PszF2a_RS13975	COG0456	acetyltransferase
PszF2a_RS13990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PszF2a_RS14015	COG2132	Multicopper oxidase
PszF2a_RS14040	COG0456	acetyltransferase
PszF2a_RS14045	COG0655	NAD(P)H dehydrogenase (quinone) activity
PszF2a_RS14060	COG2943	transferase activity, transferring hexosyl groups
PszF2a_RS14070	COG1472	Belongs to the glycosyl hydrolase 3 family
PszF2a_RS14080	COG1346	cytolysis
PszF2a_RS14085	COG1380	Effector of murein hydrolase LrgA
PszF2a_RS14090	COG0348	domain, Protein
PszF2a_RS14095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PszF2a_RS14115	COG1309	transcriptional regulator
PszF2a_RS14120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PszF2a_RS14125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PszF2a_RS14135	COG0742	ribosomal rna small subunit methyltransferase
PszF2a_RS14160	COG0563	adenylate kinase activity
PszF2a_RS14165	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PszF2a_RS14205	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PszF2a_RS14220	COG1902	pentaerythritol trinitrate reductase activity
PszF2a_RS14225	COG3383	formate dehydrogenase (NAD+) activity
PszF2a_RS14230	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PszF2a_RS14240	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PszF2a_RS14245	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PszF2a_RS14250	COG1984	allophanate hydrolase subunit 2
PszF2a_RS14255	COG4336	lyase activity
PszF2a_RS14260	COG1914	H( )-stimulated, divalent metal cation uptake system
PszF2a_RS14285	COG0545	Peptidyl-prolyl cis-trans isomerase
PszF2a_RS14300	COG2974	May be involved in recombination
PszF2a_RS14305	COG2814	Major facilitator Superfamily
PszF2a_RS14325	COG2205	protein histidine kinase activity
PszF2a_RS14330	COG3174	membrane
PszF2a_RS14365	COG0417	DNA replication proofreading
PszF2a_RS14405	COG4974	Belongs to the 'phage' integrase family
PszF2a_RS14415	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PszF2a_RS14425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PszF2a_RS14435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PszF2a_RS14445	COG0425	Belongs to the sulfur carrier protein TusA family
PszF2a_RS14455	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PszF2a_RS14460	COG0427	acetyl-CoA hydrolase
PszF2a_RS14470	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PszF2a_RS14475	COG0602	queuosine metabolic process
PszF2a_RS14480	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PszF2a_RS14485	COG2885	chlorophyll binding
PszF2a_RS14490	COG0823	Involved in the tonB-independent uptake of proteins
PszF2a_RS14510	COG0824	Thioesterase
PszF2a_RS14515	COG2255	four-way junction helicase activity
PszF2a_RS14520	COG0632	four-way junction helicase activity
PszF2a_RS14525	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PszF2a_RS14535	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PszF2a_RS14540	COG0783	Belongs to the Dps family
PszF2a_RS14550	COG2900	Belongs to the SlyX family
PszF2a_RS14565	COG0442	prolyl-tRNA aminoacylation
PszF2a_RS14580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PszF2a_RS14595	COG1295	ribonuclease BN
PszF2a_RS14615	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PszF2a_RS14620	COG0628	permease
PszF2a_RS14630	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PszF2a_RS14635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PszF2a_RS14650	COG0436	Aminotransferase
PszF2a_RS14670	COG1393	Belongs to the ArsC family
PszF2a_RS14675	COG2171	N-acyltransferase activity
PszF2a_RS14680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PszF2a_RS14685	COG2166	iron-sulfur cluster assembly
PszF2a_RS14695	COG3258	Cytochrome c
PszF2a_RS14700	COG2863	cytochrome
PszF2a_RS14710	COG3530	Putative quorum-sensing-regulated virulence factor
PszF2a_RS14720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PszF2a_RS14730	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PszF2a_RS14735	COG3932	Exopolysaccharide synthesis, ExoD
PszF2a_RS14740	COG0583	DNA-binding transcription factor activity
PszF2a_RS14745	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS14755	COG1280	lysine exporter protein (LysE YggA)
PszF2a_RS14775	COG1462	curli production assembly transport component CsgG
PszF2a_RS14795	COG1309	transcriptional regulator
PszF2a_RS14800	COG0583	DNA-binding transcription factor activity
PszF2a_RS14805	COG0189	ligase activity
PszF2a_RS14805	COG4067	protein conserved in archaea
PszF2a_RS14810	COG0116	Belongs to the methyltransferase superfamily
PszF2a_RS14810	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PszF2a_RS14815	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PszF2a_RS14830	COG0604	alcohol dehydrogenase
PszF2a_RS14830	COG3321	synthase
PszF2a_RS14840	COG3284	Transcriptional regulator
PszF2a_RS14855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PszF2a_RS14860	COG1063	alcohol dehydrogenase
PszF2a_RS14865	COG0022	dehydrogenase e1 component
PszF2a_RS14870	COG0508	dehydrogenase complex catalyzes the overall conversion of
PszF2a_RS14875	COG0508	dehydrogenase complex catalyzes the overall conversion of
PszF2a_RS14905	COG0583	DNA-binding transcription factor activity
PszF2a_RS14910	COG0625	glutathione transferase activity
PszF2a_RS14935	COG1280	lysine exporter protein (LysE YggA)
PszF2a_RS14955	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
PszF2a_RS14965	COG4249	Peptidase C14 caspase catalytic subunit p20
PszF2a_RS14970	COG1132	(ABC) transporter
PszF2a_RS15010	COG0159	tryptophan synthase activity
PszF2a_RS15025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PszF2a_RS15035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PszF2a_RS15045	COG4221	oxidoreductase activity
PszF2a_RS15055	COG2207	Transcriptional regulator
PszF2a_RS15060	COG3845	ABC transporter
PszF2a_RS15065	COG4603	Belongs to the binding-protein-dependent transport system permease family
PszF2a_RS15070	COG1079	Belongs to the binding-protein-dependent transport system permease family
PszF2a_RS15085	COG1301	dicarboxylic acid transport
PszF2a_RS15095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PszF2a_RS15100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PszF2a_RS15110	COG0471	metal ion transport
PszF2a_RS15110	COG0490	domain, Protein
PszF2a_RS15120	COG2814	Major facilitator Superfamily
PszF2a_RS15140	COG0508	dehydrogenase complex catalyzes the overall conversion of
PszF2a_RS15140	COG0596	Alpha beta hydrolase
PszF2a_RS15165	COG1279	arginine transmembrane transporter activity
PszF2a_RS15190	COG2733	membrane
PszF2a_RS15210	COG0537	adenosine 5'-monophosphoramidase activity
PszF2a_RS15235	COG3795	YCII-related domain
PszF2a_RS15250	COG2851	Citrate transporter
PszF2a_RS15260	COG1234	tRNA 3'-trailer cleavage
PszF2a_RS15275	COG3257	ureidoglycine aminohydrolase activity
PszF2a_RS15280	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PszF2a_RS15285	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PszF2a_RS15290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PszF2a_RS15295	COG0631	protein serine/threonine phosphatase activity
PszF2a_RS15300	COG0515	serine threonine protein kinase
PszF2a_RS15300	COG2815	serine threonine protein kinase
PszF2a_RS15315	COG1643	Atp-dependent helicase
PszF2a_RS15340	COG0318	PFAM AMP-dependent synthetase and ligase
PszF2a_RS15345	COG2030	dehydratase
PszF2a_RS15370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PszF2a_RS15380	COG0443	Heat shock 70 kDa protein
PszF2a_RS15385	COG2271	Major facilitator Superfamily
PszF2a_RS15390	COG3622	Belongs to the hyi family
PszF2a_RS15395	COG2084	Dehydrogenase
PszF2a_RS15400	COG1968	undecaprenyl-diphosphatase activity
PszF2a_RS15410	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PszF2a_RS15420	COG3639	organic phosphonate transmembrane transporter activity
PszF2a_RS15425	COG3639	organic phosphonate transmembrane transporter activity
PszF2a_RS15475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PszF2a_RS15510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PszF2a_RS15515	COG0556	nucleotide-excision repair
PszF2a_RS15535	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PszF2a_RS15545	COG3842	ATPase activity
PszF2a_RS15550	COG0590	tRNA wobble adenosine to inosine editing
PszF2a_RS15555	COG2132	Multicopper oxidase
PszF2a_RS15575	COG0765	amino acid transport
PszF2a_RS15580	COG0165	Argininosuccinate lyase
PszF2a_RS15590	COG1126	abc transporter atp-binding protein
PszF2a_RS15615	COG3846	protein secretion by the type IV secretion system
PszF2a_RS15630	COG3451	type IV secretory pathway VirB4
PszF2a_RS15640	COG3838	Conjugal transfer protein Trbc
PszF2a_RS15645	COG4962	Type ii secretion system protein e
PszF2a_RS15665	COG0583	DNA-binding transcription factor activity
PszF2a_RS15675	COG2814	Major facilitator Superfamily
PszF2a_RS15680	COG1104	cysteine desulfurase activity
PszF2a_RS15685	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PszF2a_RS15690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PszF2a_RS15695	COG0626	cystathionine gamma-synthase activity
PszF2a_RS15705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PszF2a_RS15710	COG2814	Major facilitator Superfamily
PszF2a_RS15715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PszF2a_RS15715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PszF2a_RS15750	COG1192	Involved in chromosome partitioning
PszF2a_RS15780	COG5489	Protein of unknown function (DUF736)
PszF2a_RS15790	COG1475	DNA binding
PszF2a_RS15805	COG2003	Belongs to the UPF0758 family
PszF2a_RS15825	COG0582	viral genome integration into host DNA
PszF2a_RS15830	COG0519	Catalyzes the synthesis of GMP from XMP
PszF2a_RS15830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PszF2a_RS15845	COG1570	exodeoxyribonuclease VII activity
PszF2a_RS15850	COG0739	heme binding
PszF2a_RS15860	COG0668	transmembrane transport
PszF2a_RS15875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PszF2a_RS15880	COG1064	alcohol dehydrogenase
PszF2a_RS15890	COG2356	endonuclease I
PszF2a_RS15895	COG3647	Membrane
PszF2a_RS15905	COG2264	protein methyltransferase activity
PszF2a_RS15920	COG0436	Aminotransferase
PszF2a_RS15925	COG1045	serine acetyltransferase
PszF2a_RS15930	COG1160	GTP binding
PszF2a_RS15940	COG2976	Protein conserved in bacteria
PszF2a_RS15945	COG0124	histidyl-tRNA synthetase
PszF2a_RS15950	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PszF2a_RS15965	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PszF2a_RS15970	COG0105	UTP biosynthetic process
PszF2a_RS15985	COG0443	Heat shock 70 kDa protein
PszF2a_RS15990	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PszF2a_RS15995	COG0316	Belongs to the HesB IscA family
PszF2a_RS16005	COG1104	cysteine desulfurase activity
PszF2a_RS16030	COG3134	Outer membrane lipoprotein
PszF2a_RS16045	COG1862	Preprotein translocase
PszF2a_RS16065	COG1278	Cold shock
PszF2a_RS16075	COG0795	lipopolysaccharide-transporting ATPase activity
PszF2a_RS16080	COG0795	lipopolysaccharide-transporting ATPase activity
PszF2a_RS16085	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PszF2a_RS16115	COG0471	metal ion transport
PszF2a_RS16115	COG0490	domain, Protein
PszF2a_RS16120	COG0477	Major facilitator Superfamily
PszF2a_RS16125	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PszF2a_RS16145	COG3081	Nucleoid-associated protein
PszF2a_RS16150	COG2326	polyphosphate kinase activity
PszF2a_RS16170	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PszF2a_RS16175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PszF2a_RS16215	COG0402	S-adenosylhomocysteine deaminase activity
PszF2a_RS16220	COG0803	Belongs to the bacterial solute-binding protein 9 family
PszF2a_RS16230	COG1121	(ABC) transporter
PszF2a_RS16235	COG1802	Transcriptional regulator
PszF2a_RS16240	COG2252	PERMEase
PszF2a_RS16265	COG4266	Belongs to the allantoicase family
PszF2a_RS16270	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
PszF2a_RS16280	COG2233	PERMEase
PszF2a_RS16285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PszF2a_RS16285	COG4651	solute:proton antiporter activity
PszF2a_RS16290	COG2233	PERMEase
PszF2a_RS16305	COG0840	transmembrane signaling receptor activity
PszF2a_RS16310	COG1309	transcriptional regulator
PszF2a_RS16335	COG2199	diguanylate cyclase activity
PszF2a_RS16335	COG2200	EAL domain
PszF2a_RS16335	COG3287	FIST C domain
PszF2a_RS16340	COG0708	Exodeoxyribonuclease III
PszF2a_RS16360	COG2351	hydroxyisourate hydrolase activity
PszF2a_RS16365	COG0583	DNA-binding transcription factor activity
PszF2a_RS16370	COG3960	tartronate-semialdehyde synthase activity
PszF2a_RS16375	COG3622	Belongs to the hyi family
PszF2a_RS16380	COG2084	Dehydrogenase
PszF2a_RS16390	COG0469	pyruvate kinase activity
PszF2a_RS16395	COG4413	Urea transporter
PszF2a_RS16405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PszF2a_RS16405	COG1017	nitric oxide dioxygenase activity
PszF2a_RS16420	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PszF2a_RS16425	COG3706	GGDEF domain
PszF2a_RS16445	COG0583	DNA-binding transcription factor activity
PszF2a_RS16450	COG1279	arginine transmembrane transporter activity
PszF2a_RS16475	COG1704	LemA family
PszF2a_RS16505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PszF2a_RS16510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PszF2a_RS16520	COG0459	protein refolding
PszF2a_RS16525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PszF2a_RS16530	COG3030	protein affecting phage T7 exclusion by the F plasmid
PszF2a_RS16540	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS16560	COG0668	transmembrane transport
PszF2a_RS16565	COG1666	GTP binding
PszF2a_RS16570	COG0745	RESPONSE REGULATOR receiver
PszF2a_RS16580	COG4191	Histidine kinase
PszF2a_RS16585	COG2096	Adenosyltransferase
PszF2a_RS16625	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PszF2a_RS16630	COG0653	protein targeting
PszF2a_RS16670	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PszF2a_RS16675	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PszF2a_RS16695	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PszF2a_RS16700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PszF2a_RS16710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PszF2a_RS16715	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PszF2a_RS16725	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PszF2a_RS16730	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PszF2a_RS16750	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PszF2a_RS16775	COG0559	Belongs to the binding-protein-dependent transport system permease family
PszF2a_RS16805	COG0318	PFAM AMP-dependent synthetase and ligase
PszF2a_RS16810	COG4294	response to UV
PszF2a_RS16815	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS16820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PszF2a_RS16825	COG1024	Enoyl-CoA hydratase
PszF2a_RS16855	COG0789	Transcriptional regulator
PszF2a_RS16860	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PszF2a_RS16870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PszF2a_RS16885	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PszF2a_RS16915	COG1403	HNH endonuclease
PszF2a_RS16920	COG0494	nUDIX hydrolase
PszF2a_RS16965	COG4128	Pfam Zonular occludens toxin
PszF2a_RS16975	COG4974	Belongs to the 'phage' integrase family
PszF2a_RS16990	COG0697	spore germination
PszF2a_RS16995	COG0288	reversible hydration of carbon dioxide
PszF2a_RS17000	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
PszF2a_RS17015	COG0456	acetyltransferase
PszF2a_RS17025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PszF2a_RS17045	COG2851	Citrate transporter
PszF2a_RS17055	COG0019	diaminopimelate decarboxylase activity
PszF2a_RS17075	COG3008	intermembrane lipid transfer
PszF2a_RS17080	COG2995	paraquat-inducible protein a
PszF2a_RS17085	COG2995	paraquat-inducible protein a
PszF2a_RS17125	COG1183	phosphatidylcholine synthase activity
PszF2a_RS17130	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PszF2a_RS17140	COG0028	Belongs to the TPP enzyme family
PszF2a_RS17160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PszF2a_RS17195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PszF2a_RS17210	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PszF2a_RS17225	COG2264	protein methyltransferase activity
PszF2a_RS17245	COG0138	bifunctional purine biosynthesis protein purh
PszF2a_RS17255	COG5002	protein histidine kinase activity
PszF2a_RS17255	COG2205	protein histidine kinase activity
PszF2a_RS17255	COG0784	Response regulator, receiver
PszF2a_RS17275	COG0679	Auxin Efflux Carrier
PszF2a_RS17290	COG0436	Aminotransferase
PszF2a_RS17295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PszF2a_RS17300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PszF2a_RS17310	COG4191	Histidine kinase
PszF2a_RS17330	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PszF2a_RS17335	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PszF2a_RS17340	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PszF2a_RS17345	COG0166	Belongs to the GPI family
PszF2a_RS17355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PszF2a_RS17380	COG1185	polyribonucleotide nucleotidyltransferase activity
PszF2a_RS17385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PszF2a_RS17390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PszF2a_RS17395	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PszF2a_RS17400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PszF2a_RS17405	COG0195	Participates in both transcription termination and antitermination
PszF2a_RS17405	COG2251	uridine kinase activity
PszF2a_RS17410	COG0779	Required for maturation of 30S ribosomal subunits
PszF2a_RS17425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PszF2a_RS17430	COG0149	triose-phosphate isomerase activity
PszF2a_RS17435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PszF2a_RS17440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PszF2a_RS17470	COG0505	Belongs to the CarA family
PszF2a_RS17475	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PszF2a_RS17480	COG0484	heat shock protein binding
PszF2a_RS17485	COG0443	Heat shock 70 kDa protein
PszF2a_RS17490	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PszF2a_RS17495	COG0497	DNA recombination
PszF2a_RS17505	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PszF2a_RS17510	COG2914	Belongs to the UPF0125 (RnfH) family
PszF2a_RS17520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PszF2a_RS17530	COG1620	l-lactate permease
PszF2a_RS17535	COG0247	lactate metabolic process
PszF2a_RS17540	COG1139	Iron-sulfur cluster binding protein
PszF2a_RS17570	COG1280	lysine exporter protein (LysE YggA)
PszF2a_RS17585	COG0366	Alpha amylase catalytic
PszF2a_RS17605	COG2909	trisaccharide binding
PszF2a_RS17610	COG3833	ABC-type maltose transport systems, permease component
PszF2a_RS17615	COG1175	transmembrane transport
PszF2a_RS17625	COG0366	Alpha amylase catalytic
PszF2a_RS17640	COG4580	involved in the transport of maltose and maltodextrins
PszF2a_RS17655	COG4989	oxidoreductase activity
PszF2a_RS17665	COG0800	Aldolase
PszF2a_RS17680	COG1737	Transcriptional regulator
PszF2a_RS17700	COG2814	Major facilitator Superfamily
PszF2a_RS17750	COG3154	lipid carrier protein
PszF2a_RS17755	COG0826	peptidase U32
PszF2a_RS17760	COG0826	peptidase U32
PszF2a_RS17770	COG3604	Transcriptional regulator
PszF2a_RS17800	COG3256	nitric oxide reductase
PszF2a_RS17805	COG2010	Cytochrome c
PszF2a_RS17830	COG3391	amine dehydrogenase activity
PszF2a_RS17835	COG2010	Cytochrome c
PszF2a_RS17855	COG2010	Cytochrome c
PszF2a_RS17860	COG0714	Associated with various cellular activities
PszF2a_RS17865	COG1845	cytochrome c oxidase, subunit III
PszF2a_RS17875	COG0535	radical SAM domain protein
PszF2a_RS17880	COG1648	precorrin-2 dehydrogenase activity
PszF2a_RS17880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PszF2a_RS17895	COG0517	IMP dehydrogenase activity
PszF2a_RS17895	COG0617	tRNA 3'-terminal CCA addition
PszF2a_RS17895	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PszF2a_RS17910	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS17930	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PszF2a_RS17945	COG4263	nitrous-oxide reductase activity
PszF2a_RS17950	COG0348	domain, Protein
PszF2a_RS17950	COG3901	Regulator of nitric oxide reductase transcription
PszF2a_RS17955	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS17970	COG3189	MarR family transcriptional regulator
PszF2a_RS17985	COG0492	ferredoxin-NADP+ reductase activity
PszF2a_RS17990	COG1760	l-serine dehydratase
PszF2a_RS18010	COG2154	pterin-4-alpha-carbinolamine dehydratase
PszF2a_RS18025	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
PszF2a_RS18040	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PszF2a_RS18045	COG0402	S-adenosylhomocysteine deaminase activity
PszF2a_RS18055	COG1607	acyl-coa hydrolase
PszF2a_RS18060	COG2824	Alkylphosphonate utilization operon protein PhnA
PszF2a_RS18065	COG1278	Cold shock
PszF2a_RS18085	COG1079	Belongs to the binding-protein-dependent transport system permease family
PszF2a_RS18095	COG3845	ABC transporter
PszF2a_RS18130	COG0346	lactoylglutathione lyase activity
PszF2a_RS18140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PszF2a_RS18150	COG4977	sequence-specific DNA binding
PszF2a_RS18165	COG1309	transcriptional regulator
PszF2a_RS18170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PszF2a_RS18175	COG1335	isochorismatase
PszF2a_RS18180	COG0251	oxidation-reduction process
PszF2a_RS18185	COG0596	Alpha beta hydrolase
PszF2a_RS18190	COG0778	Nitroreductase
PszF2a_RS18195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PszF2a_RS18225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PszF2a_RS18235	COG2814	Major facilitator Superfamily
PszF2a_RS18240	COG1309	transcriptional regulator
PszF2a_RS18250	COG2217	Heavy metal translocating P-type atpase
PszF2a_RS18260	COG0840	transmembrane signaling receptor activity
PszF2a_RS18275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PszF2a_RS18290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PszF2a_RS18290	COG2169	Transcriptional regulator
PszF2a_RS18300	COG0084	hydrolase, TatD family'
PszF2a_RS18305	COG0840	transmembrane signaling receptor activity
PszF2a_RS18315	COG3023	N-Acetylmuramoyl-L-alanine amidase
PszF2a_RS18320	COG1515	deoxyribonuclease V activity
PszF2a_RS18330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PszF2a_RS18335	COG0180	Tryptophanyl-tRNA synthetase
PszF2a_RS18340	COG2945	thiolester hydrolase activity
PszF2a_RS18365	COG1252	NADH dehydrogenase
PszF2a_RS18440	COG5001	Diguanylate cyclase
PszF2a_RS18440	COG3300	MHYT domain
PszF2a_RS18445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PszF2a_RS18450	COG0305	Participates in initiation and elongation during chromosome replication
PszF2a_RS18455	COG0359	binds to the 23S rRNA
PszF2a_RS18465	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PszF2a_RS18470	COG0360	Binds together with S18 to 16S ribosomal RNA
PszF2a_RS18480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PszF2a_RS18485	COG0557	exoribonuclease II activity
PszF2a_RS18500	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PszF2a_RS18505	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PszF2a_RS18510	COG0330	HflC and HflK could
PszF2a_RS18515	COG0330	HflC and HflK could
PszF2a_RS18520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PszF2a_RS18525	COG1923	regulation of RNA biosynthetic process
PszF2a_RS18530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PszF2a_RS18535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PszF2a_RS18540	COG0860	N-Acetylmuramoyl-L-alanine amidase
PszF2a_RS18545	COG0802	atpase or kinase
PszF2a_RS18550	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PszF2a_RS18550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PszF2a_RS18575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PszF2a_RS18585	COG0531	amino acid
PszF2a_RS18590	COG4303	Ethanolamine ammonia lyase large subunit
PszF2a_RS18610	COG3228	Belongs to the MtfA family
PszF2a_RS18630	COG2197	response regulator
PszF2a_RS18635	COG3851	Histidine kinase
PszF2a_RS18645	COG0745	RESPONSE REGULATOR receiver
PszF2a_RS18655	COG0643	Histidine kinase
PszF2a_RS18655	COG2198	Histidine kinase
PszF2a_RS18660	COG0840	transmembrane signaling receptor activity
PszF2a_RS18665	COG0835	chemotaxis
PszF2a_RS18685	COG5001	Diguanylate cyclase
PszF2a_RS18685	COG3300	MHYT domain
PszF2a_RS18695	COG0076	glutamate decarboxylase activity
PszF2a_RS18700	COG3486	L-lysine 6-monooxygenase (NADPH) activity
PszF2a_RS18725	COG1722	exodeoxyribonuclease VII activity
PszF2a_RS18730	COG0142	geranyltranstransferase activity
PszF2a_RS18735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PszF2a_RS18755	COG1028	Short-chain dehydrogenase reductase Sdr
PszF2a_RS18765	COG1643	Atp-dependent helicase
PszF2a_RS18785	COG1522	sequence-specific DNA binding
PszF2a_RS18835	COG0829	nickel cation binding
PszF2a_RS18840	COG0831	urea catabolic process
PszF2a_RS18850	COG0832	Belongs to the urease beta subunit family
PszF2a_RS18855	COG0804	urea catabolic process
PszF2a_RS18860	COG1953	Uracil, thiamine, allantoin
PszF2a_RS18865	COG5002	protein histidine kinase activity
PszF2a_RS18870	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PszF2a_RS18880	COG2814	Major facilitator Superfamily
PszF2a_RS18885	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PszF2a_RS18900	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PszF2a_RS18905	COG0830	nickel cation binding
PszF2a_RS18910	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PszF2a_RS18925	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PszF2a_RS18930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PszF2a_RS18945	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS18950	COG2205	protein histidine kinase activity
PszF2a_RS18950	COG3437	response regulator, receiver
PszF2a_RS18950	COG3850	Histidine kinase
PszF2a_RS18950	COG4999	Histidine kinase
PszF2a_RS18955	COG0351	phosphomethylpyrimidine kinase
PszF2a_RS18955	COG0352	thiamine-phosphate diphosphorylase activity
PszF2a_RS18960	COG0352	thiamine-phosphate diphosphorylase activity
PszF2a_RS18965	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PszF2a_RS18980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PszF2a_RS18985	COG1702	phosphate starvation-inducible protein PhoH
PszF2a_RS18990	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PszF2a_RS18995	COG4535	Mg2 and Co2 transporter CorC
PszF2a_RS19000	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PszF2a_RS19015	COG0495	leucyl-tRNA aminoacylation
PszF2a_RS19030	COG3036	rescue of stalled ribosome
PszF2a_RS19035	COG2951	lytic endotransglycosylase activity
PszF2a_RS19045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PszF2a_RS19050	COG0321	lipoyl(octanoyl) transferase activity
PszF2a_RS19055	COG2921	Belongs to the UPF0250 family
PszF2a_RS19060	COG1686	Belongs to the peptidase S11 family
PszF2a_RS19070	COG2951	lytic endotransglycosylase activity
PszF2a_RS19075	COG0772	Belongs to the SEDS family
PszF2a_RS19080	COG0768	penicillin binding
PszF2a_RS19085	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PszF2a_RS19095	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PszF2a_RS19100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PszF2a_RS19105	COG0586	Pfam SNARE associated Golgi protein
PszF2a_RS19115	COG1346	cytolysis
PszF2a_RS19135	COG0702	epimerase
PszF2a_RS19140	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PszF2a_RS19150	COG1162	GTPase activity
PszF2a_RS19155	COG1360	Flagellar Motor Protein
PszF2a_RS19160	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PszF2a_RS19175	COG0688	phosphatidylethanolamine metabolic process
PszF2a_RS19185	COG2200	EAL domain
PszF2a_RS19190	COG1063	alcohol dehydrogenase
PszF2a_RS19195	COG0560	Phosphoserine phosphatase
PszF2a_RS19195	COG3830	Belongs to the UPF0237 family
PszF2a_RS19230	COG3150	esterase
PszF2a_RS19235	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PszF2a_RS19245	COG0494	nUDIX hydrolase
PszF2a_RS19255	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PszF2a_RS19260	COG1538	Outer membrane efflux protein
PszF2a_RS19265	COG1519	Transferase
PszF2a_RS19280	COG0667	Aldo Keto reductase
PszF2a_RS19290	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PszF2a_RS19290	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PszF2a_RS19305	COG1132	(ABC) transporter
PszF2a_RS19330	COG3562	capsule polysaccharide
PszF2a_RS19340	COG0438	transferase activity, transferring glycosyl groups
PszF2a_RS19345	COG2192	nodulation
PszF2a_RS19375	COG0438	transferase activity, transferring glycosyl groups
PszF2a_RS19380	COG0859	PFAM glycosyl transferase family 9
PszF2a_RS19385	COG0859	PFAM glycosyl transferase family 9
PszF2a_RS19395	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PszF2a_RS19420	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PszF2a_RS19425	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS19430	COG3706	GGDEF domain
PszF2a_RS19435	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS19455	COG2226	methyltransferase
PszF2a_RS19455	COG1073	alpha beta
PszF2a_RS19460	COG0156	8-amino-7-oxononanoate synthase activity
PszF2a_RS19465	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PszF2a_RS19470	COG1040	competence protein
PszF2a_RS19475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PszF2a_RS19480	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PszF2a_RS19515	COG1304	FMN binding
PszF2a_RS19525	COG1960	acyl-CoA dehydrogenase activity
PszF2a_RS19530	COG3263	regulation of cellular component size
PszF2a_RS19535	COG1196	nuclear chromosome segregation
PszF2a_RS19535	COG3264	Mechanosensitive ion channel
PszF2a_RS19540	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PszF2a_RS19545	COG5002	protein histidine kinase activity
PszF2a_RS19555	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PszF2a_RS19560	COG2205	protein histidine kinase activity
PszF2a_RS19560	COG0784	Response regulator, receiver
PszF2a_RS19560	COG2198	Histidine kinase
PszF2a_RS19590	COG0330	HflC and HflK could
PszF2a_RS19620	COG4774	siderophore transport
PszF2a_RS19630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PszF2a_RS19640	COG2721	sulfolactate sulfo-lyase activity
PszF2a_RS19650	COG1012	belongs to the aldehyde dehydrogenase family
PszF2a_RS19655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PszF2a_RS19685	COG0583	DNA-binding transcription factor activity
PszF2a_RS19700	COG1917	Cupin 2, conserved barrel domain protein
PszF2a_RS19700	COG4977	sequence-specific DNA binding
PszF2a_RS19715	COG1609	Transcriptional regulator
PszF2a_RS19725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PszF2a_RS19735	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PszF2a_RS19785	COG0840	transmembrane signaling receptor activity
PszF2a_RS19815	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PszF2a_RS19830	COG0513	Belongs to the DEAD box helicase family
PszF2a_RS19835	COG1289	transmembrane transporter activity
PszF2a_RS19845	COG2081	HI0933 family
PszF2a_RS19885	COG0191	fructose-bisphosphate aldolase activity
PszF2a_RS19900	COG0126	phosphoglycerate kinase activity
PszF2a_RS19905	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PszF2a_RS19910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PszF2a_RS19915	COG0583	DNA-binding transcription factor activity
PszF2a_RS19920	COG2175	clavaminate synthase activity
PszF2a_RS19930	COG2226	methyltransferase
PszF2a_RS19935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PszF2a_RS19945	COG0842	Transport permease protein
PszF2a_RS19950	COG1131	(ABC) transporter
PszF2a_RS19955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PszF2a_RS19960	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PszF2a_RS19980	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PszF2a_RS19985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PszF2a_RS19990	COG0513	Belongs to the DEAD box helicase family
PszF2a_RS20005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PszF2a_RS20010	COG2353	YceI-like domain
PszF2a_RS20015	COG3038	cytochrome b561
PszF2a_RS20025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PszF2a_RS20035	COG2201	protein-glutamate methylesterase activity
PszF2a_RS20040	COG0784	Response regulator, receiver
PszF2a_RS20040	COG0643	Histidine kinase
PszF2a_RS20040	COG2198	Histidine kinase
PszF2a_RS20080	COG1678	Uncharacterized ACR, COG1678
PszF2a_RS20095	COG0540	Belongs to the ATCase OTCase family
PszF2a_RS20150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PszF2a_RS20155	COG2813	Specifically methylates the guanine in position
PszF2a_RS20155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PszF2a_RS20165	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PszF2a_RS20170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PszF2a_RS20195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PszF2a_RS20210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PszF2a_RS20215	COG2022	thiamine diphosphate biosynthetic process
PszF2a_RS20225	COG2363	Small membrane protein
PszF2a_RS20230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PszF2a_RS20250	COG2177	Part of the ABC transporter FtsEX involved in
PszF2a_RS20255	COG2884	Cell division ATP-binding protein ftsE
PszF2a_RS20260	COG0552	protein localization to endoplasmic reticulum
PszF2a_RS20265	COG0612	Peptidase, M16
PszF2a_RS20270	COG0612	Peptidase, M16
PszF2a_RS20275	COG0742	ribosomal rna small subunit methyltransferase
PszF2a_RS20305	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PszF2a_RS20310	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PszF2a_RS20315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PszF2a_RS20335	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PszF2a_RS20345	COG0693	protein deglycase activity
PszF2a_RS20360	COG0129	dihydroxy-acid dehydratase activity
PszF2a_RS20365	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
PszF2a_RS20390	COG0584	glycerophosphoryl diester phosphodiesterase
PszF2a_RS20400	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PszF2a_RS20415	COG0704	Plays a role in the regulation of phosphate uptake
PszF2a_RS20420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PszF2a_RS20425	COG0573	inorganic phosphate transmembrane transporter activity
PszF2a_RS20440	COG1607	acyl-coa hydrolase
PszF2a_RS20445	COG4251	negative regulation of phosphorylation
PszF2a_RS20445	COG3706	GGDEF domain
PszF2a_RS20445	COG2203	Gaf domain
PszF2a_RS20445	COG5001	Diguanylate cyclase
PszF2a_RS20460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PszF2a_RS20465	COG1074	ATP-dependent DNA helicase activity
PszF2a_RS20470	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PszF2a_RS20485	COG3180	Ammonia monooxygenase
PszF2a_RS20520	COG4251	negative regulation of phosphorylation
PszF2a_RS20520	COG5001	Diguanylate cyclase
PszF2a_RS20520	COG3706	GGDEF domain
PszF2a_RS20520	COG2203	Gaf domain
PszF2a_RS20525	COG0840	transmembrane signaling receptor activity
PszF2a_RS20540	COG2358	TRAP transporter, solute receptor (TAXI family
PszF2a_RS20550	COG0700	Nucleoside recognition
PszF2a_RS20570	COG2204	response regulator
PszF2a_RS20575	COG5002	protein histidine kinase activity
PszF2a_RS20585	COG3023	N-Acetylmuramoyl-L-alanine amidase
PszF2a_RS20610	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PszF2a_RS20615	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PszF2a_RS20615	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PszF2a_RS20630	COG1178	ABC-type Fe3 transport system permease component
PszF2a_RS20640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PszF2a_RS20650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PszF2a_RS20655	COG0006	proline dipeptidase activity
PszF2a_RS20660	COG3079	Belongs to the UPF0149 family
PszF2a_RS20680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PszF2a_RS20705	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PszF2a_RS20715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PszF2a_RS20720	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PszF2a_RS20725	COG4942	peptidase
PszF2a_RS20730	COG0793	Belongs to the peptidase S41A family
PszF2a_RS20735	COG2861	carbohydrate metabolic process
PszF2a_RS20750	COG0107	imidazoleglycerol-phosphate synthase activity
PszF2a_RS20755	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PszF2a_RS20770	COG0131	Imidazoleglycerol-phosphate dehydratase
PszF2a_RS20775	COG3707	response regulator
PszF2a_RS20780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PszF2a_RS20790	COG1116	anion transmembrane transporter activity
PszF2a_RS20805	COG1194	a g-specific adenine glycosylase
PszF2a_RS20810	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PszF2a_RS20820	COG1525	nuclease
PszF2a_RS20855	COG0676	glucose-6-phosphate 1-epimerase activity
PszF2a_RS20875	COG0840	transmembrane signaling receptor activity
PszF2a_RS20890	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PszF2a_RS20910	COG3052	prosthetic group binding
PszF2a_RS20915	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
PszF2a_RS20925	COG4221	oxidoreductase activity
PszF2a_RS20930	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
PszF2a_RS20945	COG2358	TRAP transporter, solute receptor (TAXI family
PszF2a_RS20985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PszF2a_RS20995	COG3360	Dodecin
PszF2a_RS21000	COG0625	glutathione transferase activity
PszF2a_RS21020	COG0737	Belongs to the 5'-nucleotidase family
PszF2a_RS21035	COG3340	Belongs to the peptidase S51 family
PszF2a_RS21040	COG1132	(ABC) transporter
PszF2a_RS21065	COG2323	membrane
PszF2a_RS21070	COG0583	DNA-binding transcription factor activity
PszF2a_RS21105	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PszF2a_RS21110	COG0339	signal peptide processing
PszF2a_RS21140	COG0659	secondary active sulfate transmembrane transporter activity
PszF2a_RS21150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PszF2a_RS21155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PszF2a_RS21160	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PszF2a_RS21190	COG0109	protoheme IX farnesyltransferase activity
PszF2a_RS21215	COG1595	DNA-templated transcription, initiation
PszF2a_RS21230	COG0523	cobalamin synthesis protein
PszF2a_RS21245	COG4251	negative regulation of phosphorylation
PszF2a_RS21250	COG0784	Response regulator, receiver
PszF2a_RS21265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PszF2a_RS21270	COG1349	DNA-binding transcription factor activity
PszF2a_RS21280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PszF2a_RS21285	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PszF2a_RS21290	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PszF2a_RS21295	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PszF2a_RS21300	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PszF2a_RS21305	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PszF2a_RS21310	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PszF2a_RS21320	COG0356	it plays a direct role in the translocation of protons across the membrane
PszF2a_RS21330	COG1475	DNA binding
PszF2a_RS21335	COG1192	Involved in chromosome partitioning
PszF2a_RS21340	COG0357	Ribosomal RNA small subunit methyltransferase G
PszF2a_RS21345	COG0445	tRNA wobble uridine modification
PszF2a_RS21350	COG1320	monovalent cation:proton antiporter activity
PszF2a_RS21365	COG0651	ATP synthesis coupled electron transport
PszF2a_RS21370	COG1006	Multisubunit Na H antiporter MnhC subunit
PszF2a_RS21375	COG2111	Na H antiporter
PszF2a_RS21380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PszF2a_RS21380	COG2111	Na H antiporter
PszF2a_RS21385	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PszF2a_RS21390	COG0706	membrane insertase activity
PszF2a_RS21395	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PszF2a_RS21400	COG0594	ribonuclease P activity
PszF2a_RS21405	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PszF2a_RS21465	COG2124	cytochrome p450
PszF2a_RS21470	COG2124	cytochrome p450