locus-tag	class	description
KVH38_RS00010	COG1175	transmembrane transport
KVH38_RS00015	COG3833	ABC-type maltose transport systems, permease component
KVH38_RS00020	COG2909	trisaccharide binding
KVH38_RS00035	COG0366	Alpha amylase catalytic
KVH38_RS00050	COG1280	lysine exporter protein (LysE YggA)
KVH38_RS00105	COG3436	PFAM IS66 Orf2 family protein
KVH38_RS00110	COG4372	Transposase
KVH38_RS00115	COG3012	SEC-C Motif Domain Protein
KVH38_RS00245	COG0469	pyruvate kinase activity
KVH38_RS00260	COG2015	COG2015, Alkyl sulfatase and related hydrolases
KVH38_RS00265	COG2135	peptidase activity
KVH38_RS00345	COG1139	Iron-sulfur cluster binding protein
KVH38_RS00350	COG0247	lactate metabolic process
KVH38_RS00355	COG1620	l-lactate permease
KVH38_RS00365	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KVH38_RS00375	COG2914	Belongs to the UPF0125 (RnfH) family
KVH38_RS00380	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KVH38_RS00390	COG0497	DNA recombination
KVH38_RS00395	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KVH38_RS00400	COG0443	Heat shock 70 kDa protein
KVH38_RS00405	COG0484	heat shock protein binding
KVH38_RS00410	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KVH38_RS00415	COG0505	Belongs to the CarA family
KVH38_RS00445	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KVH38_RS00450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KVH38_RS00455	COG0149	triose-phosphate isomerase activity
KVH38_RS00460	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KVH38_RS00475	COG0779	Required for maturation of 30S ribosomal subunits
KVH38_RS00480	COG0195	Participates in both transcription termination and antitermination
KVH38_RS00480	COG2251	uridine kinase activity
KVH38_RS00485	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KVH38_RS00490	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KVH38_RS00495	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KVH38_RS00500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KVH38_RS00505	COG1185	polyribonucleotide nucleotidyltransferase activity
KVH38_RS00530	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KVH38_RS00540	COG0166	Belongs to the GPI family
KVH38_RS00545	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KVH38_RS00550	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KVH38_RS00555	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KVH38_RS00575	COG4191	Histidine kinase
KVH38_RS00585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KVH38_RS00590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KVH38_RS00595	COG0436	Aminotransferase
KVH38_RS00610	COG0679	Auxin Efflux Carrier
KVH38_RS00625	COG2124	cytochrome p450
KVH38_RS00630	COG2205	protein histidine kinase activity
KVH38_RS00630	COG5002	protein histidine kinase activity
KVH38_RS00630	COG0784	Response regulator, receiver
KVH38_RS00640	COG0138	bifunctional purine biosynthesis protein purh
KVH38_RS00660	COG2264	protein methyltransferase activity
KVH38_RS00675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KVH38_RS00690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KVH38_RS00725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KVH38_RS00745	COG0028	Belongs to the TPP enzyme family
KVH38_RS00755	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KVH38_RS00760	COG1183	phosphatidylcholine synthase activity
KVH38_RS00800	COG2995	paraquat-inducible protein a
KVH38_RS00805	COG2995	paraquat-inducible protein a
KVH38_RS00810	COG3008	intermembrane lipid transfer
KVH38_RS00830	COG0019	diaminopimelate decarboxylase activity
KVH38_RS00840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KVH38_RS00850	COG0456	acetyltransferase
KVH38_RS00860	COG1877	trehalose-phosphatase activity
KVH38_RS00865	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KVH38_RS00870	COG0288	reversible hydration of carbon dioxide
KVH38_RS00875	COG0697	spore germination
KVH38_RS00915	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KVH38_RS00930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KVH38_RS00940	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KVH38_RS00945	COG0789	Transcriptional regulator
KVH38_RS00975	COG1024	Enoyl-CoA hydratase
KVH38_RS00980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KVH38_RS00985	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS00990	COG4294	response to UV
KVH38_RS00995	COG0318	PFAM AMP-dependent synthetase and ligase
KVH38_RS01025	COG0559	Belongs to the binding-protein-dependent transport system permease family
KVH38_RS01045	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KVH38_RS01075	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KVH38_RS01095	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KVH38_RS01100	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KVH38_RS01110	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KVH38_RS01115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KVH38_RS01125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KVH38_RS01130	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KVH38_RS01150	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS01165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KVH38_RS01175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KVH38_RS01180	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KVH38_RS01220	COG0653	protein targeting
KVH38_RS01225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KVH38_RS01265	COG2096	Adenosyltransferase
KVH38_RS01270	COG4191	Histidine kinase
KVH38_RS01280	COG0745	RESPONSE REGULATOR receiver
KVH38_RS01285	COG1666	GTP binding
KVH38_RS01290	COG0668	transmembrane transport
KVH38_RS01310	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS01320	COG3030	protein affecting phage T7 exclusion by the F plasmid
KVH38_RS01325	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KVH38_RS01330	COG0459	protein refolding
KVH38_RS01340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KVH38_RS01345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KVH38_RS01375	COG1704	LemA family
KVH38_RS01400	COG1279	arginine transmembrane transporter activity
KVH38_RS01405	COG0583	DNA-binding transcription factor activity
KVH38_RS01425	COG3706	GGDEF domain
KVH38_RS01430	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KVH38_RS01445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KVH38_RS01445	COG1017	nitric oxide dioxygenase activity
KVH38_RS01455	COG4413	Urea transporter
KVH38_RS01460	COG0469	pyruvate kinase activity
KVH38_RS01470	COG2084	Dehydrogenase
KVH38_RS01475	COG3622	Belongs to the hyi family
KVH38_RS01480	COG3960	tartronate-semialdehyde synthase activity
KVH38_RS01485	COG0583	DNA-binding transcription factor activity
KVH38_RS01490	COG2351	hydroxyisourate hydrolase activity
KVH38_RS01510	COG0708	Exodeoxyribonuclease III
KVH38_RS01515	COG3300	MHYT domain
KVH38_RS01515	COG5001	Diguanylate cyclase
KVH38_RS01525	COG3344	reverse transcriptase
KVH38_RS01545	COG1309	transcriptional regulator
KVH38_RS01550	COG0840	transmembrane signaling receptor activity
KVH38_RS01565	COG2233	PERMEase
KVH38_RS01570	COG4651	solute:proton antiporter activity
KVH38_RS01570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KVH38_RS01575	COG2233	PERMEase
KVH38_RS01585	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KVH38_RS01590	COG4266	Belongs to the allantoicase family
KVH38_RS01615	COG2252	PERMEase
KVH38_RS01620	COG1802	Transcriptional regulator
KVH38_RS01625	COG1121	(ABC) transporter
KVH38_RS01635	COG0803	Belongs to the bacterial solute-binding protein 9 family
KVH38_RS01640	COG0402	S-adenosylhomocysteine deaminase activity
KVH38_RS01680	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KVH38_RS01685	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KVH38_RS01705	COG2326	polyphosphate kinase activity
KVH38_RS01710	COG3081	Nucleoid-associated protein
KVH38_RS01730	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KVH38_RS01735	COG0477	Major facilitator Superfamily
KVH38_RS01740	COG0490	domain, Protein
KVH38_RS01740	COG0471	metal ion transport
KVH38_RS01770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KVH38_RS01775	COG0795	lipopolysaccharide-transporting ATPase activity
KVH38_RS01780	COG0795	lipopolysaccharide-transporting ATPase activity
KVH38_RS01790	COG1278	Cold shock
KVH38_RS01810	COG1862	Preprotein translocase
KVH38_RS01825	COG3134	Outer membrane lipoprotein
KVH38_RS01850	COG1104	cysteine desulfurase activity
KVH38_RS01860	COG0316	Belongs to the HesB IscA family
KVH38_RS01865	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KVH38_RS01870	COG0443	Heat shock 70 kDa protein
KVH38_RS01885	COG0105	UTP biosynthetic process
KVH38_RS01890	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KVH38_RS01905	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KVH38_RS01910	COG0124	histidyl-tRNA synthetase
KVH38_RS01915	COG2976	Protein conserved in bacteria
KVH38_RS01925	COG1160	GTP binding
KVH38_RS01930	COG1045	serine acetyltransferase
KVH38_RS01935	COG0436	Aminotransferase
KVH38_RS01950	COG2264	protein methyltransferase activity
KVH38_RS01960	COG3647	Membrane
KVH38_RS01965	COG2356	endonuclease I
KVH38_RS01975	COG1064	alcohol dehydrogenase
KVH38_RS01980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KVH38_RS01995	COG0668	transmembrane transport
KVH38_RS02005	COG0739	heme binding
KVH38_RS02010	COG1570	exodeoxyribonuclease VII activity
KVH38_RS02025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KVH38_RS02025	COG0519	Catalyzes the synthesis of GMP from XMP
KVH38_RS02030	COG2132	Multicopper oxidase
KVH38_RS02035	COG0590	tRNA wobble adenosine to inosine editing
KVH38_RS02040	COG3842	ATPase activity
KVH38_RS02050	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KVH38_RS02070	COG0556	nucleotide-excision repair
KVH38_RS02075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KVH38_RS02110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KVH38_RS02160	COG3639	organic phosphonate transmembrane transporter activity
KVH38_RS02165	COG3639	organic phosphonate transmembrane transporter activity
KVH38_RS02175	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
KVH38_RS02185	COG1968	undecaprenyl-diphosphatase activity
KVH38_RS02190	COG2084	Dehydrogenase
KVH38_RS02195	COG3622	Belongs to the hyi family
KVH38_RS02205	COG0443	Heat shock 70 kDa protein
KVH38_RS02215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KVH38_RS02240	COG2030	dehydratase
KVH38_RS02245	COG0318	PFAM AMP-dependent synthetase and ligase
KVH38_RS02250	COG0318	PFAM AMP-dependent synthetase and ligase
KVH38_RS02270	COG1643	Atp-dependent helicase
KVH38_RS02285	COG0515	serine threonine protein kinase
KVH38_RS02285	COG2815	serine threonine protein kinase
KVH38_RS02290	COG0631	protein serine/threonine phosphatase activity
KVH38_RS02295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KVH38_RS02300	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KVH38_RS02305	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KVH38_RS02310	COG3257	ureidoglycine aminohydrolase activity
KVH38_RS02325	COG1234	tRNA 3'-trailer cleavage
KVH38_RS02335	COG2851	Citrate transporter
KVH38_RS02350	COG3795	YCII-related domain
KVH38_RS02365	COG2258	MOSC domain
KVH38_RS02375	COG0537	adenosine 5'-monophosphoramidase activity
KVH38_RS02395	COG2733	membrane
KVH38_RS02420	COG1279	arginine transmembrane transporter activity
KVH38_RS02465	COG2814	Major facilitator Superfamily
KVH38_RS02475	COG0490	domain, Protein
KVH38_RS02475	COG0471	metal ion transport
KVH38_RS02490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KVH38_RS02500	COG1301	dicarboxylic acid transport
KVH38_RS02515	COG1079	Belongs to the binding-protein-dependent transport system permease family
KVH38_RS02520	COG4603	Belongs to the binding-protein-dependent transport system permease family
KVH38_RS02525	COG3845	ABC transporter
KVH38_RS02530	COG2207	Transcriptional regulator
KVH38_RS02550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KVH38_RS02560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KVH38_RS02575	COG0159	tryptophan synthase activity
KVH38_RS02615	COG1132	(ABC) transporter
KVH38_RS02620	COG4249	Peptidase C14 caspase catalytic subunit p20
KVH38_RS02630	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KVH38_RS02650	COG1280	lysine exporter protein (LysE YggA)
KVH38_RS02660	COG1696	Membrane protein involved in D-alanine export
KVH38_RS02670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KVH38_RS02680	COG0659	secondary active sulfate transmembrane transporter activity
KVH38_RS02705	COG0625	glutathione transferase activity
KVH38_RS02710	COG0583	DNA-binding transcription factor activity
KVH38_RS02745	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KVH38_RS02765	COG2188	Transcriptional regulator
KVH38_RS02800	COG0508	dehydrogenase complex catalyzes the overall conversion of
KVH38_RS02805	COG0508	dehydrogenase complex catalyzes the overall conversion of
KVH38_RS02810	COG0022	dehydrogenase e1 component
KVH38_RS02815	COG1063	alcohol dehydrogenase
KVH38_RS02820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KVH38_RS02835	COG3284	Transcriptional regulator
KVH38_RS02845	COG3321	synthase
KVH38_RS02845	COG0604	alcohol dehydrogenase
KVH38_RS02860	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KVH38_RS02865	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KVH38_RS02865	COG0116	Belongs to the methyltransferase superfamily
KVH38_RS02870	COG0189	ligase activity
KVH38_RS02870	COG4067	protein conserved in archaea
KVH38_RS02875	COG0583	DNA-binding transcription factor activity
KVH38_RS02880	COG1309	transcriptional regulator
KVH38_RS02900	COG1462	curli production assembly transport component CsgG
KVH38_RS02920	COG1280	lysine exporter protein (LysE YggA)
KVH38_RS02930	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS02935	COG0583	DNA-binding transcription factor activity
KVH38_RS02940	COG3932	Exopolysaccharide synthesis, ExoD
KVH38_RS02945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KVH38_RS02955	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KVH38_RS02965	COG3530	Putative quorum-sensing-regulated virulence factor
KVH38_RS02975	COG2863	cytochrome
KVH38_RS02980	COG3258	Cytochrome c
KVH38_RS02990	COG2166	iron-sulfur cluster assembly
KVH38_RS02995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KVH38_RS03000	COG2171	N-acyltransferase activity
KVH38_RS03005	COG1393	Belongs to the ArsC family
KVH38_RS03025	COG0436	Aminotransferase
KVH38_RS03040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KVH38_RS03045	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KVH38_RS03055	COG0628	permease
KVH38_RS03060	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KVH38_RS03075	COG1393	Belongs to the ArsC family
KVH38_RS03080	COG1295	ribonuclease BN
KVH38_RS03095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KVH38_RS03110	COG0442	prolyl-tRNA aminoacylation
KVH38_RS03125	COG2900	Belongs to the SlyX family
KVH38_RS03135	COG0783	Belongs to the Dps family
KVH38_RS03140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KVH38_RS03150	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KVH38_RS03155	COG0632	four-way junction helicase activity
KVH38_RS03160	COG2255	four-way junction helicase activity
KVH38_RS03165	COG0824	Thioesterase
KVH38_RS03185	COG0823	Involved in the tonB-independent uptake of proteins
KVH38_RS03190	COG2885	chlorophyll binding
KVH38_RS03195	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KVH38_RS03200	COG0602	queuosine metabolic process
KVH38_RS03205	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KVH38_RS03215	COG0427	acetyl-CoA hydrolase
KVH38_RS03220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KVH38_RS03230	COG0425	Belongs to the sulfur carrier protein TusA family
KVH38_RS03240	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KVH38_RS03250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KVH38_RS03260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KVH38_RS03330	COG0417	DNA replication proofreading
KVH38_RS03365	COG3174	membrane
KVH38_RS03370	COG2205	protein histidine kinase activity
KVH38_RS03390	COG2814	Major facilitator Superfamily
KVH38_RS03395	COG2974	May be involved in recombination
KVH38_RS03410	COG0545	Peptidyl-prolyl cis-trans isomerase
KVH38_RS03435	COG1914	H( )-stimulated, divalent metal cation uptake system
KVH38_RS03440	COG4336	lyase activity
KVH38_RS03445	COG1984	allophanate hydrolase subunit 2
KVH38_RS03450	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KVH38_RS03455	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KVH38_RS03465	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KVH38_RS03470	COG0243	molybdopterin cofactor binding
KVH38_RS03475	COG1902	pentaerythritol trinitrate reductase activity
KVH38_RS03490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KVH38_RS03530	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KVH38_RS03535	COG0563	adenylate kinase activity
KVH38_RS03560	COG0742	ribosomal rna small subunit methyltransferase
KVH38_RS03570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KVH38_RS03575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KVH38_RS03600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KVH38_RS03605	COG0348	domain, Protein
KVH38_RS03610	COG1380	Effector of murein hydrolase LrgA
KVH38_RS03615	COG1346	cytolysis
KVH38_RS03625	COG1472	Belongs to the glycosyl hydrolase 3 family
KVH38_RS03650	COG0655	NAD(P)H dehydrogenase (quinone) activity
KVH38_RS03655	COG0456	acetyltransferase
KVH38_RS03680	COG2132	Multicopper oxidase
KVH38_RS03705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KVH38_RS03720	COG0456	acetyltransferase
KVH38_RS03725	COG2937	Belongs to the GPAT DAPAT family
KVH38_RS03750	COG0456	acetyltransferase
KVH38_RS03755	COG1131	(ABC) transporter
KVH38_RS03780	COG2226	methyltransferase
KVH38_RS03785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KVH38_RS03790	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KVH38_RS03830	COG0513	Belongs to the DEAD box helicase family
KVH38_RS03845	COG0583	DNA-binding transcription factor activity
KVH38_RS03865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KVH38_RS03865	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KVH38_RS03870	COG2205	protein histidine kinase activity
KVH38_RS03870	COG0784	Response regulator, receiver
KVH38_RS03870	COG5002	protein histidine kinase activity
KVH38_RS03875	COG2860	membrane
KVH38_RS03890	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KVH38_RS03895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KVH38_RS03900	COG3956	TIGRFAM MazG family protein
KVH38_RS03930	COG1201	RNA secondary structure unwinding
KVH38_RS03935	COG1793	dna ligase
KVH38_RS03950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KVH38_RS03960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KVH38_RS03975	COG1805	sodium ion transport
KVH38_RS03990	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KVH38_RS04000	COG1477	protein flavinylation
KVH38_RS04010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KVH38_RS04015	COG0584	glycerophosphoryl diester phosphodiesterase
KVH38_RS04030	COG4591	ABC-type transport system involved in lipoprotein release permease component
KVH38_RS04035	COG1136	(ABC) transporter
KVH38_RS04050	COG0658	competence protein
KVH38_RS04050	COG2333	competence protein COMEC
KVH38_RS04055	COG0811	peptide transport
KVH38_RS04065	COG1663	tetraacyldisaccharide 4'-kinase activity
KVH38_RS04070	COG2835	tetraacyldisaccharide 4'-kinase activity
KVH38_RS04075	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KVH38_RS04080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KVH38_RS04085	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KVH38_RS04090	COG1530	ribonuclease E activity
KVH38_RS04105	COG0616	signal peptide processing
KVH38_RS04105	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KVH38_RS04110	COG0424	maF-like protein
KVH38_RS04120	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KVH38_RS04125	COG0416	fatty acid biosynthetic process
KVH38_RS04140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KVH38_RS04145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KVH38_RS04155	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KVH38_RS04160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KVH38_RS04175	COG0084	hydrolase, TatD family'
KVH38_RS04180	COG1113	amino acid transport
KVH38_RS04240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KVH38_RS04250	COG3300	MHYT domain
KVH38_RS04250	COG5001	Diguanylate cyclase
KVH38_RS04265	COG2130	NADP-dependent
KVH38_RS04315	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KVH38_RS04320	COG2226	methyltransferase
KVH38_RS04330	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KVH38_RS04335	COG0583	DNA-binding transcription factor activity
KVH38_RS04355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KVH38_RS04365	COG0745	RESPONSE REGULATOR receiver
KVH38_RS04370	COG2205	protein histidine kinase activity
KVH38_RS04380	COG0668	transmembrane transport
KVH38_RS04425	COG2988	succinylglutamate desuccinylase activity
KVH38_RS04430	COG1131	(ABC) transporter
KVH38_RS04435	COG0842	Transport permease protein
KVH38_RS04440	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KVH38_RS04440	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KVH38_RS04450	COG2853	Lipoprotein
KVH38_RS04460	COG0745	RESPONSE REGULATOR receiver
KVH38_RS04470	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KVH38_RS04490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KVH38_RS04525	COG2814	Major facilitator Superfamily
KVH38_RS04530	COG4948	Mandelate Racemase Muconate Lactonizing
KVH38_RS04535	COG4829	muconolactone delta-isomerase
KVH38_RS04540	COG3485	protocatechuate 3,4-dioxygenase
KVH38_RS04545	COG3135	benzoate transporter
KVH38_RS04580	COG0784	Response regulator, receiver
KVH38_RS04580	COG4191	Histidine kinase
KVH38_RS04590	COG0114	fumarate hydratase activity
KVH38_RS04600	COG0271	Belongs to the BolA IbaG family
KVH38_RS04605	COG1054	Belongs to the UPF0176 family
KVH38_RS04620	COG0840	transmembrane signaling receptor activity
KVH38_RS04645	COG0583	DNA-binding transcription factor activity
KVH38_RS04650	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
KVH38_RS04655	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS04665	COG2079	MmgE PrpD family protein
KVH38_RS04675	COG2301	Belongs to the HpcH HpaI aldolase family
KVH38_RS04705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KVH38_RS04710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KVH38_RS04730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KVH38_RS04740	COG1770	oligopeptidase
KVH38_RS04745	COG1024	Enoyl-CoA hydratase
KVH38_RS04745	COG1250	3-hydroxyacyl-CoA dehydrogenase
KVH38_RS04750	COG0183	Belongs to the thiolase family
KVH38_RS04815	COG0653	protein targeting
KVH38_RS04835	COG0133	tryptophan synthase activity
KVH38_RS04840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KVH38_RS04845	COG1012	belongs to the aldehyde dehydrogenase family
KVH38_RS04850	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KVH38_RS04855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KVH38_RS04880	COG0297	glycogen (starch) synthase activity
KVH38_RS04910	COG0250	Participates in transcription elongation, termination and antitermination
KVH38_RS04945	COG3039	Transposase
KVH38_RS04975	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS04990	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KVH38_RS04995	COG0066	3-isopropylmalate dehydratase activity
KVH38_RS05025	COG0135	phosphoribosylanthranilate isomerase activity
KVH38_RS05030	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KVH38_RS05035	COG0285	dihydrofolate synthase activity
KVH38_RS05040	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KVH38_RS05045	COG1286	toxin biosynthetic process
KVH38_RS05080	COG0789	Transcriptional regulator
KVH38_RS05110	COG4771	TonB-dependent receptor
KVH38_RS05115	COG0254	rRNA binding
KVH38_RS05135	COG2814	Major facilitator Superfamily
KVH38_RS05160	COG1271	oxidase subunit
KVH38_RS05165	COG1294	oxidase, subunit
KVH38_RS05185	COG0446	pyridine nucleotide-disulphide oxidoreductase
KVH38_RS05185	COG1902	pentaerythritol trinitrate reductase activity
KVH38_RS05215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KVH38_RS05230	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KVH38_RS05235	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KVH38_RS05250	COG0573	inorganic phosphate transmembrane transporter activity
KVH38_RS05265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KVH38_RS05270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KVH38_RS05280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KVH38_RS05310	COG2010	Cytochrome c
KVH38_RS05325	COG3278	Belongs to the heme-copper respiratory oxidase family
KVH38_RS05330	COG2010	Cytochrome c
KVH38_RS05340	COG3278	Belongs to the heme-copper respiratory oxidase family
KVH38_RS05350	COG0840	transmembrane signaling receptor activity
KVH38_RS05360	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KVH38_RS05380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KVH38_RS05385	COG2010	Cytochrome c
KVH38_RS05385	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KVH38_RS05400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KVH38_RS05405	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KVH38_RS05415	COG3115	cell septum assembly
KVH38_RS05420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KVH38_RS05455	COG3123	guanosine phosphorylase activity
KVH38_RS05470	COG2009	succinate dehydrogenase
KVH38_RS05475	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KVH38_RS05480	COG1053	succinate dehydrogenase
KVH38_RS05485	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KVH38_RS05505	COG0045	succinate-CoA ligase (ADP-forming) activity
KVH38_RS05540	COG0326	Molecular chaperone. Has ATPase activity
KVH38_RS05570	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KVH38_RS05580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KVH38_RS05585	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KVH38_RS05620	COG0628	permease
KVH38_RS05630	COG0709	Synthesizes selenophosphate from selenide and ATP
KVH38_RS05635	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
KVH38_RS05645	COG0714	Associated with various cellular activities
KVH38_RS05670	COG1238	metal cluster binding
KVH38_RS05685	COG0183	Belongs to the thiolase family
KVH38_RS05690	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS05695	COG0318	PFAM AMP-dependent synthetase and ligase
KVH38_RS05700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KVH38_RS05710	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS05715	COG1024	Enoyl-CoA hydratase
KVH38_RS05745	COG0058	SHG alpha-glucan phosphorylase activity
KVH38_RS05760	COG2207	Transcriptional regulator
KVH38_RS05775	COG4991	sh3 domain protein
KVH38_RS05780	COG4191	Histidine kinase
KVH38_RS05780	COG0784	Response regulator, receiver
KVH38_RS05785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KVH38_RS05805	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KVH38_RS05820	COG5002	protein histidine kinase activity
KVH38_RS05820	COG5001	Diguanylate cyclase
KVH38_RS05820	COG3447	MASE1 domain protein
KVH38_RS05825	COG3012	SEC-C Motif Domain Protein
KVH38_RS05830	COG4372	Transposase
KVH38_RS05835	COG3436	PFAM IS66 Orf2 family protein
KVH38_RS05880	COG0210	DNA helicase
KVH38_RS05885	COG0515	serine threonine protein kinase
KVH38_RS05895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KVH38_RS05895	COG2146	nitrite reductase [NAD(P)H] activity
KVH38_RS05900	COG2146	nitrite reductase [NAD(P)H] activity
KVH38_RS05900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KVH38_RS05915	COG0840	transmembrane signaling receptor activity
KVH38_RS05920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KVH38_RS05935	COG4221	oxidoreductase activity
KVH38_RS05945	COG0415	Belongs to the DNA photolyase family
KVH38_RS05950	COG0789	Transcriptional regulator
KVH38_RS05955	COG3272	Protein of unknown function (DUF1722)
KVH38_RS05960	COG1090	epimerase
KVH38_RS05965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KVH38_RS05975	COG1366	Belongs to the anti-sigma-factor antagonist family
KVH38_RS05995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KVH38_RS06000	COG0302	gtp cyclohydrolase
KVH38_RS06010	COG0789	Transcriptional regulator
KVH38_RS06015	COG1025	Belongs to the peptidase M16 family
KVH38_RS06030	COG0784	Response regulator, receiver
KVH38_RS06030	COG2205	protein histidine kinase activity
KVH38_RS06035	COG0435	Glutathione S-transferase
KVH38_RS06040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KVH38_RS06095	COG0174	glutamine synthetase
KVH38_RS06100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KVH38_RS06105	COG1116	anion transmembrane transporter activity
KVH38_RS06110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KVH38_RS06120	COG1335	isochorismatase
KVH38_RS06140	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS06150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KVH38_RS06165	COG0439	Biotin carboxylase
KVH38_RS06175	COG3665	Urea carboxylase-associated protein
KVH38_RS06180	COG3842	ATPase activity
KVH38_RS06195	COG0084	hydrolase, TatD family'
KVH38_RS06200	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KVH38_RS06205	COG5380	lipid catabolic process
KVH38_RS06220	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KVH38_RS06225	COG4181	ATPase activity
KVH38_RS06270	COG1376	ErfK ybiS ycfS ynhG family protein
KVH38_RS06285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KVH38_RS06290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KVH38_RS06305	COG0560	Phosphoserine phosphatase
KVH38_RS06330	COG1802	Transcriptional regulator
KVH38_RS06340	COG0372	Belongs to the citrate synthase family
KVH38_RS06355	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KVH38_RS06365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KVH38_RS06380	COG0668	transmembrane transport
KVH38_RS06415	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KVH38_RS06420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KVH38_RS06430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KVH38_RS06435	COG0215	cysteine-tRNA ligase activity
KVH38_RS06440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KVH38_RS06445	COG3039	Transposase
KVH38_RS06465	COG2186	Transcriptional regulator
KVH38_RS06475	COG0544	peptidyl-prolyl cis-trans isomerase activity
KVH38_RS06485	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KVH38_RS06490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KVH38_RS06500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KVH38_RS06505	COG0167	dihydroorotate dehydrogenase activity
KVH38_RS06510	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KVH38_RS06510	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KVH38_RS06550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KVH38_RS06555	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
KVH38_RS06565	COG0535	radical SAM domain protein
KVH38_RS06580	COG5002	protein histidine kinase activity
KVH38_RS06595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KVH38_RS06600	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KVH38_RS06655	COG0798	PFAM Bile acid sodium symporter
KVH38_RS06660	COG2072	flavoprotein involved in K transport
KVH38_RS06665	COG0640	Transcriptional regulator
KVH38_RS06670	COG0431	NADPH-dependent FMN reductase
KVH38_RS06680	COG1742	UPF0060 membrane protein
KVH38_RS06685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KVH38_RS06710	COG5642	Protein of unknown function (DUF2384)
KVH38_RS06760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KVH38_RS06785	COG1566	PFAM secretion protein HlyD family protein
KVH38_RS06795	COG0583	DNA-binding transcription factor activity
KVH38_RS06810	COG0723	plastoquinol--plastocyanin reductase activity
KVH38_RS06815	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS06820	COG0028	Belongs to the TPP enzyme family
KVH38_RS06845	COG3685	Protein conserved in bacteria
KVH38_RS06850	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KVH38_RS06850	COG3264	Mechanosensitive ion channel
KVH38_RS06855	COG1058	Belongs to the CinA family
KVH38_RS06855	COG1546	Belongs to the CinA family
KVH38_RS06860	COG0297	glycogen (starch) synthase activity
KVH38_RS06865	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KVH38_RS06890	COG0739	heme binding
KVH38_RS06900	COG3384	dioxygenase
KVH38_RS06905	COG0583	DNA-binding transcription factor activity
KVH38_RS06920	COG3568	Endonuclease Exonuclease Phosphatase
KVH38_RS06925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KVH38_RS06930	COG0392	lysyltransferase activity
KVH38_RS06935	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KVH38_RS06940	COG0366	Alpha amylase catalytic
KVH38_RS06960	COG2864	formate dehydrogenase
KVH38_RS06965	COG0437	4 iron, 4 sulfur cluster binding
KVH38_RS06985	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS06990	COG0604	alcohol dehydrogenase
KVH38_RS06990	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS06990	COG3321	synthase
KVH38_RS07040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KVH38_RS07050	COG0728	peptidoglycan biosynthetic process
KVH38_RS07065	COG1115	amino acid carrier protein
KVH38_RS07070	COG2911	Protein conserved in bacteria
KVH38_RS07075	COG0729	surface antigen
KVH38_RS07110	COG1175	transmembrane transport
KVH38_RS07130	COG1070	Carbohydrate kinase
KVH38_RS07145	COG1609	Transcriptional regulator
KVH38_RS07150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KVH38_RS07155	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KVH38_RS07160	COG3265	gluconokinase activity
KVH38_RS07165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KVH38_RS07170	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KVH38_RS07195	COG0488	(ABC) transporter
KVH38_RS07200	COG1968	undecaprenyl-diphosphatase activity
KVH38_RS07205	COG0840	transmembrane signaling receptor activity
KVH38_RS07220	COG2323	membrane
KVH38_RS07235	COG3706	GGDEF domain
KVH38_RS07240	COG2201	protein-glutamate methylesterase activity
KVH38_RS07245	COG0316	Belongs to the HesB IscA family
KVH38_RS07245	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KVH38_RS07265	COG2755	lipolytic protein G-D-S-L family
KVH38_RS07265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KVH38_RS07290	COG2223	nitrite transmembrane transporter activity
KVH38_RS07295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KVH38_RS07310	COG0071	Belongs to the small heat shock protein (HSP20) family
KVH38_RS07335	COG0604	alcohol dehydrogenase
KVH38_RS07340	COG0616	signal peptide processing
KVH38_RS07360	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS07375	COG2816	NAD+ diphosphatase activity
KVH38_RS07385	COG1024	Enoyl-CoA hydratase
KVH38_RS07395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KVH38_RS07400	COG0328	RNA-DNA hybrid ribonuclease activity
KVH38_RS07415	COG0741	lytic transglycosylase activity
KVH38_RS07415	COG1388	LysM domain
KVH38_RS07425	COG4166	transmembrane transport
KVH38_RS07435	COG4174	ABC transporter (Permease)
KVH38_RS07440	COG4239	(ABC) transporter, permease
KVH38_RS07445	COG4172	Belongs to the ABC transporter superfamily
KVH38_RS07475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KVH38_RS07485	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KVH38_RS07535	COG0840	transmembrane signaling receptor activity
KVH38_RS07555	COG1131	(ABC) transporter
KVH38_RS07575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KVH38_RS07575	COG1648	precorrin-2 dehydrogenase activity
KVH38_RS07580	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KVH38_RS07585	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KVH38_RS07590	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KVH38_RS07595	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KVH38_RS07605	COG0492	ferredoxin-NADP+ reductase activity
KVH38_RS07610	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KVH38_RS07615	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KVH38_RS07620	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KVH38_RS07625	COG0542	response to heat
KVH38_RS07630	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KVH38_RS07655	COG0482	sulfurtransferase activity
KVH38_RS07660	COG2915	High frequency lysogenization protein hflD homolog
KVH38_RS07670	COG2850	peptidyl-arginine hydroxylation
KVH38_RS07675	COG2153	protein acetylation
KVH38_RS07700	COG0628	permease
KVH38_RS07705	COG2056	Na+-H+ antiporter family
KVH38_RS07710	COG0720	synthase
KVH38_RS07740	COG0402	S-adenosylhomocysteine deaminase activity
KVH38_RS07745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KVH38_RS07750	COG0546	phosphoglycolate phosphatase activity
KVH38_RS07755	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS07765	COG0800	Aldolase
KVH38_RS07790	COG2840	Smr protein MutS2
KVH38_RS07800	COG0625	glutathione transferase activity
KVH38_RS07805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KVH38_RS07815	COG3344	reverse transcriptase
KVH38_RS07825	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KVH38_RS07830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KVH38_RS07840	COG0077	Prephenate dehydratase
KVH38_RS07840	COG1605	Chorismate mutase
KVH38_RS07845	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KVH38_RS07855	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KVH38_RS07860	COG3039	Transposase
KVH38_RS07875	COG0587	DNA-directed DNA polymerase activity
KVH38_RS07890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KVH38_RS07895	COG0765	amino acid transport
KVH38_RS07900	COG1126	abc transporter atp-binding protein
KVH38_RS07915	COG0745	RESPONSE REGULATOR receiver
KVH38_RS07930	COG0776	regulation of translation
KVH38_RS07935	COG0072	phenylalanine-tRNA ligase activity
KVH38_RS07940	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KVH38_RS07945	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KVH38_RS07950	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KVH38_RS07960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KVH38_RS07970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KVH38_RS08045	COG3171	Protein conserved in bacteria
KVH38_RS08050	COG2027	D-alanyl-D-alanine carboxypeptidase
KVH38_RS08055	COG0116	Belongs to the methyltransferase superfamily
KVH38_RS08055	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KVH38_RS08060	COG3130	regulation of translation
KVH38_RS08065	COG0167	dihydroorotate dehydrogenase activity
KVH38_RS08085	COG0714	Associated with various cellular activities
KVH38_RS08105	COG2304	oxidoreductase activity
KVH38_RS08115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KVH38_RS08120	COG3707	response regulator
KVH38_RS08140	COG2223	nitrite transmembrane transporter activity
KVH38_RS08145	COG2815	serine threonine protein kinase
KVH38_RS08145	COG0515	serine threonine protein kinase
KVH38_RS08155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KVH38_RS08160	COG2146	nitrite reductase [NAD(P)H] activity
KVH38_RS08165	COG0243	molybdopterin cofactor binding
KVH38_RS08185	COG0308	aminopeptidase N
KVH38_RS08205	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KVH38_RS08210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KVH38_RS08225	COG0730	response to heat
KVH38_RS08240	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KVH38_RS08265	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KVH38_RS08275	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KVH38_RS08295	COG3842	ATPase activity
KVH38_RS08300	COG0395	ABC-type sugar transport system, permease component
KVH38_RS08305	COG1175	transmembrane transport
KVH38_RS08310	COG1653	transport
KVH38_RS08335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KVH38_RS08345	COG0180	Tryptophanyl-tRNA synthetase
KVH38_RS08350	COG0009	L-threonylcarbamoyladenylate synthase
KVH38_RS08355	COG0613	PHP domain protein
KVH38_RS08360	COG2350	Protein conserved in bacteria
KVH38_RS08370	COG0745	RESPONSE REGULATOR receiver
KVH38_RS08385	COG0778	Nitroreductase
KVH38_RS08390	COG0727	PFAM Uncharacterised protein family (UPF0153)
KVH38_RS08395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KVH38_RS08400	COG2354	Protein conserved in bacteria
KVH38_RS08420	COG2207	Transcriptional regulator
KVH38_RS08435	COG1752	Esterase of the alpha-beta hydrolase superfamily
KVH38_RS08445	COG0514	ATP-dependent DNA helicase (RecQ)
KVH38_RS08455	COG2832	Protein of unknown function (DUF454)
KVH38_RS08470	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KVH38_RS08480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KVH38_RS08490	COG0542	response to heat
KVH38_RS08510	COG0121	glutamine amidotransferase
KVH38_RS08520	COG0589	response to stress
KVH38_RS08530	COG0488	(ABC) transporter
KVH38_RS08535	COG0741	lytic transglycosylase activity
KVH38_RS08540	COG3217	Mosc domain protein beta barrel domain protein
KVH38_RS08540	COG0633	Ferredoxin
KVH38_RS08545	COG3437	response regulator, receiver
KVH38_RS08555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KVH38_RS08560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KVH38_RS08565	COG3206	protein involved in exopolysaccharide biosynthesis
KVH38_RS08565	COG0489	protein tyrosine kinase activity
KVH38_RS08570	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KVH38_RS08610	COG0183	Belongs to the thiolase family
KVH38_RS08645	COG1086	Polysaccharide biosynthesis protein
KVH38_RS08660	COG0438	transferase activity, transferring glycosyl groups
KVH38_RS08695	COG3206	protein involved in exopolysaccharide biosynthesis
KVH38_RS08695	COG0489	protein tyrosine kinase activity
KVH38_RS08695	COG0489	protein tyrosine kinase activity
KVH38_RS08695	COG3206	protein involved in exopolysaccharide biosynthesis
KVH38_RS08700	COG0776	regulation of translation
KVH38_RS08710	COG0840	transmembrane signaling receptor activity
KVH38_RS08715	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KVH38_RS08720	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KVH38_RS08725	COG0471	metal ion transport
KVH38_RS08730	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KVH38_RS08745	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
KVH38_RS08770	COG4591	ABC-type transport system involved in lipoprotein release permease component
KVH38_RS08775	COG1136	(ABC) transporter
KVH38_RS08785	COG3453	Protein conserved in bacteria
KVH38_RS08785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KVH38_RS08815	COG0640	Transcriptional regulator
KVH38_RS08850	COG0386	Belongs to the glutathione peroxidase family
KVH38_RS08855	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KVH38_RS08860	COG0436	Aminotransferase
KVH38_RS08870	COG0501	Belongs to the peptidase M48B family
KVH38_RS08880	COG0500	methyltransferase
KVH38_RS08930	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KVH38_RS08960	COG2257	FlhB HrpN YscU SpaS Family
KVH38_RS08975	COG0835	chemotaxis
KVH38_RS08985	COG1192	Involved in chromosome partitioning
KVH38_RS08990	COG1360	Flagellar Motor Protein
KVH38_RS08995	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KVH38_RS09000	COG2201	protein-glutamate methylesterase activity
KVH38_RS09005	COG0643	Histidine kinase
KVH38_RS09005	COG0784	Response regulator, receiver
KVH38_RS09005	COG2198	Histidine kinase
KVH38_RS09010	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KVH38_RS09040	COG2032	superoxide dismutase activity
KVH38_RS09055	COG1987	bacterial-type flagellum assembly
KVH38_RS09095	COG0745	RESPONSE REGULATOR receiver
KVH38_RS09130	COG1677	Flagellar hook-basal body complex protein FliE
KVH38_RS09135	COG3135	benzoate transporter
KVH38_RS09145	COG0789	Transcriptional regulator
KVH38_RS09175	COG0826	peptidase U32
KVH38_RS09180	COG0840	transmembrane signaling receptor activity
KVH38_RS09195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KVH38_RS09215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KVH38_RS09230	COG1283	sodium-dependent phosphate transmembrane transporter activity
KVH38_RS09240	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KVH38_RS09245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KVH38_RS09295	COG0004	ammonium transporteR
KVH38_RS09310	COG2258	MOSC domain
KVH38_RS09320	COG0217	transcriptional regulatory protein
KVH38_RS09330	COG0589	response to stress
KVH38_RS09385	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KVH38_RS09390	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KVH38_RS09395	COG0585	pseudouridine synthase activity
KVH38_RS09400	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KVH38_RS09410	COG1902	pentaerythritol trinitrate reductase activity
KVH38_RS09415	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KVH38_RS09425	COG0583	DNA-binding transcription factor activity
KVH38_RS09440	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KVH38_RS09455	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KVH38_RS09460	COG0504	CTP synthase activity
KVH38_RS09465	COG0037	tRNA processing
KVH38_RS09470	COG0825	malonyl-CoA metabolic process
KVH38_RS09480	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KVH38_RS09485	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KVH38_RS09490	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KVH38_RS09495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KVH38_RS09500	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KVH38_RS09520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KVH38_RS09530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KVH38_RS09535	COG0233	cytoplasmic translational termination
KVH38_RS09540	COG0528	UMP kinase activity
KVH38_RS09545	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KVH38_RS09550	COG0052	Belongs to the universal ribosomal protein uS2 family
KVH38_RS09555	COG0024	Methionine aminopeptidase
KVH38_RS09560	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KVH38_RS09565	COG1320	monovalent cation:proton antiporter activity
KVH38_RS09570	COG2212	antiporter activity
KVH38_RS09575	COG1863	multisubunit Na H antiporter MnhE subunit
KVH38_RS09580	COG0651	ATP synthesis coupled electron transport
KVH38_RS09585	COG1006	Multisubunit Na H antiporter MnhC subunit
KVH38_RS09590	COG2111	Na H antiporter
KVH38_RS09590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KVH38_RS09605	COG0259	pyridoxamine-phosphate oxidase activity
KVH38_RS09615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KVH38_RS09620	COG1199	ATP-dependent helicase activity
KVH38_RS09640	COG3012	SEC-C Motif Domain Protein
KVH38_RS09650	COG0583	DNA-binding transcription factor activity
KVH38_RS09660	COG0697	spore germination
KVH38_RS09665	COG3148	PFAM DTW domain containing protein
KVH38_RS09675	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
KVH38_RS09680	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KVH38_RS09690	COG2137	regulation of response to DNA damage stimulus
KVH38_RS09695	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KVH38_RS09700	COG1546	Belongs to the CinA family
KVH38_RS09710	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KVH38_RS09715	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KVH38_RS09735	COG0438	transferase activity, transferring glycosyl groups
KVH38_RS09740	COG1295	ribonuclease BN
KVH38_RS09815	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KVH38_RS09830	COG2996	Protein conserved in bacteria
KVH38_RS09835	COG4993	Dehydrogenase
KVH38_RS09840	COG2133	pyrroloquinoline quinone binding
KVH38_RS09880	COG1201	RNA secondary structure unwinding
KVH38_RS09890	COG4221	oxidoreductase activity
KVH38_RS09900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KVH38_RS09910	COG4935	Belongs to the peptidase S8 family
KVH38_RS09910	COG1404	Belongs to the peptidase S8 family
KVH38_RS09920	COG0367	asparagine synthase
KVH38_RS09925	COG0189	ligase activity
KVH38_RS09925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KVH38_RS09930	COG1363	Peptidase, m42
KVH38_RS09940	COG3089	Belongs to the UPF0270 family
KVH38_RS09960	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KVH38_RS09965	COG3162	membrane
KVH38_RS09980	COG2853	Lipoprotein
KVH38_RS09990	COG1560	Kdo2-lipid A biosynthetic process
KVH38_RS09995	COG0850	regulation of cytokinetic process
KVH38_RS10000	COG2894	cell division
KVH38_RS10005	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KVH38_RS10010	COG0564	pseudouridine synthase activity
KVH38_RS10015	COG1362	aminopeptidase activity
KVH38_RS10020	COG4942	peptidase
KVH38_RS10060	COG2199	diguanylate cyclase activity
KVH38_RS10060	COG2200	EAL domain
KVH38_RS10085	COG1555	photosystem II stabilization
KVH38_RS10090	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KVH38_RS10105	COG3754	Rhamnan synthesis protein F
KVH38_RS10135	COG1706	bacterial-type flagellum-dependent cell motility
KVH38_RS10140	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KVH38_RS10150	COG4787	bacterial-type flagellum-dependent cell motility
KVH38_RS10170	COG1815	bacterial-type flagellum-dependent cell motility
KVH38_RS10175	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KVH38_RS10180	COG0835	chemotaxis
KVH38_RS10180	COG0784	Response regulator, receiver
KVH38_RS10200	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KVH38_RS10230	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KVH38_RS10235	COG0511	ligase activity, forming carbon-carbon bonds
KVH38_RS10235	COG5016	pyruvate
KVH38_RS10240	COG3630	sodium ion export across plasma membrane
KVH38_RS10245	COG2239	Acts as a magnesium transporter
KVH38_RS10270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KVH38_RS10275	COG0527	aspartate kinase activity
KVH38_RS10280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KVH38_RS10295	COG2983	Belongs to the UPF0260 family
KVH38_RS10305	COG3100	YcgL domain-containing protein
KVH38_RS10320	COG2067	long-chain fatty acid transport protein
KVH38_RS10350	COG0251	oxidation-reduction process
KVH38_RS10360	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KVH38_RS10370	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KVH38_RS10380	COG1492	cobalamin metabolic process
KVH38_RS10390	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KVH38_RS10400	COG0778	Nitroreductase
KVH38_RS10405	COG1797	cobyrinic acid a,c-diamide synthase activity
KVH38_RS10420	COG4206	TonB-dependent receptor
KVH38_RS10435	COG0791	NLP P60 protein
KVH38_RS10440	COG0791	NLP P60 protein
KVH38_RS10455	COG4890	Cyd operon protein YbgT
KVH38_RS10460	COG1294	oxidase, subunit
KVH38_RS10485	COG2818	Glycosylase
KVH38_RS10490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KVH38_RS10495	COG0037	tRNA processing
KVH38_RS10520	COG2814	Major facilitator Superfamily
KVH38_RS10525	COG4459	periplasmic nitrate reductase
KVH38_RS10535	COG0243	molybdopterin cofactor binding
KVH38_RS10545	COG3005	denitrification pathway
KVH38_RS10550	COG0717	Belongs to the dCTP deaminase family
KVH38_RS10555	COG1278	Cold shock
KVH38_RS10560	COG0489	protein tyrosine kinase activity
KVH38_RS10565	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KVH38_RS10565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KVH38_RS10590	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
KVH38_RS10680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KVH38_RS10685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KVH38_RS10700	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KVH38_RS10705	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KVH38_RS10710	COG1414	Transcriptional regulator
KVH38_RS10715	COG0679	Auxin Efflux Carrier
KVH38_RS10720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KVH38_RS10725	COG3485	protocatechuate 3,4-dioxygenase
KVH38_RS10730	COG3485	protocatechuate 3,4-dioxygenase
KVH38_RS10735	COG0583	DNA-binding transcription factor activity
KVH38_RS10745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KVH38_RS10760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KVH38_RS10775	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KVH38_RS10785	COG2226	methyltransferase
KVH38_RS10790	COG0500	methyltransferase
KVH38_RS10800	COG0583	DNA-binding transcription factor activity
KVH38_RS10810	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KVH38_RS10815	COG1381	Involved in DNA repair and RecF pathway recombination
KVH38_RS10825	COG0571	ribonuclease III activity
KVH38_RS10840	COG0481	GTPase activity
KVH38_RS10845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KVH38_RS10885	COG0354	folic acid binding
KVH38_RS10900	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KVH38_RS10910	COG1024	Enoyl-CoA hydratase
KVH38_RS10925	COG4657	Part of a membrane complex involved in electron transport
KVH38_RS10930	COG2878	Part of a membrane complex involved in electron transport
KVH38_RS10940	COG4658	electron transport chain
KVH38_RS10945	COG4659	FMN binding
KVH38_RS10955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KVH38_RS10965	COG0346	lactoylglutathione lyase activity
KVH38_RS10970	COG0137	argininosuccinate synthase activity
KVH38_RS10980	COG0418	dihydroorotase activity
KVH38_RS10985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KVH38_RS11000	COG3791	Glutathione-dependent formaldehyde-activating
KVH38_RS11015	COG0335	large ribosomal subunit rRNA binding
KVH38_RS11020	COG0336	Belongs to the RNA methyltransferase TrmD family
KVH38_RS11025	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KVH38_RS11030	COG0228	four-way junction DNA binding
KVH38_RS11035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KVH38_RS11040	COG4137	Cytochrome C assembly protein
KVH38_RS11045	COG4536	flavin adenine dinucleotide binding
KVH38_RS11110	COG3039	Transposase
KVH38_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS11145	COG0318	PFAM AMP-dependent synthetase and ligase
KVH38_RS11165	COG4372	Transposase
KVH38_RS11215	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KVH38_RS11215	COG0047	phosphoribosylformylglycinamidine synthase activity
KVH38_RS11220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KVH38_RS11225	COG0400	carboxylic ester hydrolase activity
KVH38_RS11245	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KVH38_RS11250	COG0315	cyclic pyranopterin monophosphate synthase activity
KVH38_RS11255	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KVH38_RS11265	COG3022	response to hydroperoxide
KVH38_RS11280	COG0433	COG0433 Predicted ATPase
KVH38_RS11290	COG0788	formyltetrahydrofolate deformylase activity
KVH38_RS11300	COG3344	reverse transcriptase
KVH38_RS11315	COG2925	Exonuclease
KVH38_RS11340	COG0714	Associated with various cellular activities
KVH38_RS11365	COG0469	pyruvate kinase activity
KVH38_RS11385	COG4628	conserved protein (DUF2132)
KVH38_RS11390	COG0693	protein deglycase activity
KVH38_RS11395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KVH38_RS11435	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS11440	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KVH38_RS11455	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
KVH38_RS11465	COG1309	transcriptional regulator
KVH38_RS11470	COG0386	Belongs to the glutathione peroxidase family
KVH38_RS11480	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KVH38_RS11490	COG0204	Acyl-transferase
KVH38_RS11500	COG0784	Response regulator, receiver
KVH38_RS11500	COG2205	protein histidine kinase activity
KVH38_RS11505	COG2885	chlorophyll binding
KVH38_RS11510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KVH38_RS11520	COG0318	PFAM AMP-dependent synthetase and ligase
KVH38_RS11525	COG1280	lysine exporter protein (LysE YggA)
KVH38_RS11530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KVH38_RS11535	COG2813	Specifically methylates the guanine in position
KVH38_RS11540	COG2119	membrane
KVH38_RS11550	COG0501	Belongs to the peptidase M48B family
KVH38_RS11555	COG0840	transmembrane signaling receptor activity
KVH38_RS11610	COG0659	secondary active sulfate transmembrane transporter activity
KVH38_RS11615	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS11640	COG1285	pathogenesis
KVH38_RS11685	COG1181	Belongs to the D-alanine--D-alanine ligase family
KVH38_RS11690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KVH38_RS11695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KVH38_RS11700	COG0772	Belongs to the SEDS family
KVH38_RS11705	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KVH38_RS11710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KVH38_RS11715	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KVH38_RS11720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KVH38_RS11735	COG0275	rRNA processing
KVH38_RS11760	COG0792	nuclease activity
KVH38_RS11765	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KVH38_RS11770	COG2823	Periplasmic or secreted lipoprotein
KVH38_RS11775	COG2969	positive regulation of protein catabolic process
KVH38_RS11780	COG0625	glutathione transferase activity
KVH38_RS11785	COG2857	Cytochrome c1
KVH38_RS11790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KVH38_RS11795	COG0723	plastoquinol--plastocyanin reductase activity
KVH38_RS11800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KVH38_RS11805	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KVH38_RS11810	COG0667	Aldo Keto reductase
KVH38_RS11825	COG0237	dephospho-CoA kinase activity
KVH38_RS11830	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KVH38_RS11885	COG0175	sulfate reduction
KVH38_RS11895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KVH38_RS11900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KVH38_RS11910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KVH38_RS11915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KVH38_RS11940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KVH38_RS11945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KVH38_RS11950	COG1127	ABC transporter
KVH38_RS11960	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KVH38_RS11975	COG1137	ATPase activity
KVH38_RS11980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KVH38_RS11995	COG1660	Displays ATPase and GTPase activities
KVH38_RS12000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KVH38_RS12005	COG0312	modulator of DNA gyrase
KVH38_RS12015	COG0312	modulator of DNA gyrase
KVH38_RS12020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KVH38_RS12030	COG1530	ribonuclease E activity
KVH38_RS12050	COG1792	Involved in formation and maintenance of cell shape
KVH38_RS12055	COG1077	Cell shape determining protein MreB Mrl
KVH38_RS12060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KVH38_RS12070	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KVH38_RS12085	COG0530	calcium, potassium:sodium antiporter activity
KVH38_RS12100	COG0739	heme binding
KVH38_RS12110	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KVH38_RS12125	COG4771	TonB-dependent receptor
KVH38_RS12145	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KVH38_RS12150	COG4774	siderophore transport
KVH38_RS12155	COG3128	pkhd-type hydroxylase
KVH38_RS12165	COG0019	diaminopimelate decarboxylase activity
KVH38_RS12170	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KVH38_RS12175	COG2852	Protein conserved in bacteria
KVH38_RS12180	COG4993	Dehydrogenase
KVH38_RS12185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KVH38_RS12185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KVH38_RS12185	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KVH38_RS12190	COG1105	Belongs to the carbohydrate kinase PfkB family
KVH38_RS12195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KVH38_RS12195	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KVH38_RS12210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KVH38_RS12240	COG0534	Mate efflux family protein
KVH38_RS12255	COG0023	Translation Initiation Factor
KVH38_RS12260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KVH38_RS12265	COG4968	Prepilin-type N-terminal cleavage methylation domain
KVH38_RS12300	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KVH38_RS12305	COG1047	Peptidyl-prolyl cis-trans
KVH38_RS12310	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KVH38_RS12315	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KVH38_RS12320	COG0196	riboflavin kinase activity
KVH38_RS12330	COG0268	Binds directly to 16S ribosomal RNA
KVH38_RS12335	COG3045	CreA protein
KVH38_RS12340	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KVH38_RS12345	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KVH38_RS12350	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KVH38_RS12355	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KVH38_RS12360	COG0142	geranyltranstransferase activity
KVH38_RS12370	COG0545	Peptidyl-prolyl cis-trans isomerase
KVH38_RS12380	COG3046	protein related to deoxyribodipyrimidine photolyase
KVH38_RS12390	COG2862	Uncharacterized protein family, UPF0114
KVH38_RS12400	COG1067	ATP-dependent peptidase activity
KVH38_RS12410	COG1970	mechanosensitive ion channel activity
KVH38_RS12415	COG2841	Protein conserved in bacteria
KVH38_RS12435	COG2020	methyltransferase activity
KVH38_RS12440	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KVH38_RS12445	COG0488	(ABC) transporter
KVH38_RS12480	COG2813	Specifically methylates the guanine in position
KVH38_RS12485	COG0789	Transcriptional regulator
KVH38_RS12510	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KVH38_RS12515	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KVH38_RS12520	COG2080	2 iron, 2 sulfur cluster binding
KVH38_RS12525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KVH38_RS12530	COG3608	succinylglutamate desuccinylase aspartoacylase
KVH38_RS12530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KVH38_RS12540	COG2252	PERMEase
KVH38_RS12545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KVH38_RS12550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KVH38_RS12555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KVH38_RS12600	COG3642	lipopolysaccharide core region biosynthetic process
KVH38_RS12625	COG0318	PFAM AMP-dependent synthetase and ligase
KVH38_RS12655	COG3038	cytochrome b561
KVH38_RS12665	COG0521	Mo-molybdopterin cofactor biosynthetic process
KVH38_RS12680	COG2181	nitrate reductase activity
KVH38_RS12685	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KVH38_RS12690	COG1140	nitrate reductase beta subunit
KVH38_RS12695	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KVH38_RS12700	COG2223	nitrite transmembrane transporter activity
KVH38_RS12710	COG2223	nitrite transmembrane transporter activity
KVH38_RS12715	COG3850	Histidine kinase
KVH38_RS12720	COG2197	response regulator
KVH38_RS12745	COG2321	neutral zinc metallopeptidase
KVH38_RS12755	COG1946	Acyl-CoA thioesterase
KVH38_RS12765	COG0123	including yeast histone deacetylase and acetoin utilization protein
KVH38_RS12790	COG0513	Belongs to the DEAD box helicase family
KVH38_RS12795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KVH38_RS12795	COG4651	solute:proton antiporter activity
KVH38_RS12815	COG0733	neurotransmitter:sodium symporter activity
KVH38_RS12820	COG0625	glutathione transferase activity
KVH38_RS12830	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KVH38_RS12840	COG3344	reverse transcriptase
KVH38_RS12845	COG0733	neurotransmitter:sodium symporter activity
KVH38_RS12860	COG1522	sequence-specific DNA binding
KVH38_RS12870	COG2031	fatty acid transporter
KVH38_RS12875	COG2610	gluconate transmembrane transporter activity
KVH38_RS12880	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS12885	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KVH38_RS12890	COG1040	competence protein
KVH38_RS12950	COG0420	3'-5' exonuclease activity
KVH38_RS12965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KVH38_RS12975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KVH38_RS12980	COG3577	Aspartyl protease
KVH38_RS12985	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KVH38_RS12995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KVH38_RS13000	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KVH38_RS13015	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KVH38_RS13015	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KVH38_RS13030	COG2264	protein methyltransferase activity
KVH38_RS13040	COG0425	Belongs to the sulfur carrier protein TusA family
KVH38_RS13045	COG2391	methyltransferase activity
KVH38_RS13050	COG3118	belongs to the thioredoxin family
KVH38_RS13065	COG4181	ATPase activity
KVH38_RS13085	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KVH38_RS13090	COG0848	biopolymer transport protein
KVH38_RS13095	COG0811	peptide transport
KVH38_RS13100	COG0811	peptide transport
KVH38_RS13110	COG3047	cAMP biosynthetic process
KVH38_RS13130	COG2814	Major facilitator Superfamily
KVH38_RS13145	COG0203	ribosomal protein L17
KVH38_RS13150	COG0202	RNA polymerase activity
KVH38_RS13155	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KVH38_RS13160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KVH38_RS13165	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KVH38_RS13170	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KVH38_RS13180	COG0200	Binds to the 23S rRNA
KVH38_RS13185	COG1841	ribosomal large subunit assembly
KVH38_RS13190	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KVH38_RS13200	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KVH38_RS13205	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KVH38_RS13210	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KVH38_RS13215	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KVH38_RS13220	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KVH38_RS13225	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KVH38_RS13230	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KVH38_RS13235	COG0255	Belongs to the universal ribosomal protein uL29 family
KVH38_RS13240	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KVH38_RS13245	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KVH38_RS13250	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KVH38_RS13255	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KVH38_RS13260	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KVH38_RS13265	COG0089	rRNA binding
KVH38_RS13270	COG0088	Forms part of the polypeptide exit tunnel
KVH38_RS13275	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KVH38_RS13280	COG0051	transcription antitermination factor activity, RNA binding
KVH38_RS13285	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KVH38_RS13290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KVH38_RS13295	COG0049	tRNA binding
KVH38_RS13300	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KVH38_RS13305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KVH38_RS13310	COG0085	RNA polymerase activity
KVH38_RS13315	COG0222	ribosome binding
KVH38_RS13320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KVH38_RS13325	COG0081	regulation of translation
KVH38_RS13330	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KVH38_RS13350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KVH38_RS13375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KVH38_RS13380	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KVH38_RS13380	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KVH38_RS13410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KVH38_RS13415	COG0739	heme binding
KVH38_RS13420	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KVH38_RS13425	COG0316	Belongs to the HesB IscA family
KVH38_RS13430	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KVH38_RS13435	COG1981	membrane
KVH38_RS13445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KVH38_RS13450	COG0537	adenosine 5'-monophosphoramidase activity
KVH38_RS13455	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KVH38_RS13460	COG1765	OsmC-like protein
KVH38_RS13470	COG0134	indole-3-glycerol-phosphate synthase activity
KVH38_RS13475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KVH38_RS13480	COG0512	Glutamine amidotransferase of anthranilate synthase
KVH38_RS13490	COG0546	phosphoglycolate phosphatase activity
KVH38_RS13495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KVH38_RS13500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KVH38_RS13510	COG1177	transmembrane transport
KVH38_RS13515	COG1176	ABC-type spermidine putrescine transport system, permease component I
KVH38_RS13525	COG3842	ATPase activity
KVH38_RS13530	COG2197	response regulator
KVH38_RS13550	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KVH38_RS13560	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KVH38_RS13565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KVH38_RS13570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KVH38_RS13575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KVH38_RS13580	COG2967	ApaG domain
KVH38_RS13585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KVH38_RS13590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KVH38_RS13595	COG2766	serine protein kinase
KVH38_RS13600	COG2718	Belongs to the UPF0229 family
KVH38_RS13605	COG2719	SpoVR family
KVH38_RS13610	COG0617	tRNA 3'-terminal CCA addition
KVH38_RS13625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KVH38_RS13630	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KVH38_RS13635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KVH38_RS13640	COG0358	DNA primase activity
KVH38_RS13645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KVH38_RS13655	COG0471	metal ion transport
KVH38_RS13655	COG3273	potassium ion transport
KVH38_RS13660	COG2873	o-acetylhomoserine
KVH38_RS13665	COG3118	belongs to the thioredoxin family
KVH38_RS13675	COG0583	DNA-binding transcription factor activity
KVH38_RS13680	COG2814	Major facilitator Superfamily
KVH38_RS13690	COG0493	'glutamate synthase
KVH38_RS13695	COG0070	glutamate synthase
KVH38_RS13695	COG0067	glutamate synthase
KVH38_RS13695	COG0069	glutamate synthase activity
KVH38_RS13705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KVH38_RS13740	COG0281	malic enzyme
KVH38_RS13750	COG0254	rRNA binding
KVH38_RS13755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KVH38_RS13760	COG0018	arginyl-trna synthetase
KVH38_RS13775	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KVH38_RS13790	COG0248	Ppx GppA phosphatase
KVH38_RS13795	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KVH38_RS13805	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KVH38_RS13820	COG1671	Belongs to the UPF0178 family
KVH38_RS13830	COG0861	Integral membrane protein TerC family
KVH38_RS13840	COG0488	(ABC) transporter
KVH38_RS13860	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KVH38_RS13880	COG0181	hydroxymethylbilane synthase activity
KVH38_RS13890	COG3275	phosphorelay sensor kinase activity
KVH38_RS13895	COG0165	Argininosuccinate lyase
KVH38_RS13930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KVH38_RS13935	COG1965	Belongs to the frataxin family
KVH38_RS13950	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KVH38_RS13960	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KVH38_RS13975	COG0432	Pfam Uncharacterised protein family UPF0047
KVH38_RS13980	COG0004	ammonium transporteR
KVH38_RS13985	COG0004	ammonium transporteR
KVH38_RS13990	COG0347	Belongs to the P(II) protein family
KVH38_RS14000	COG0606	chelatase, subunit chli
KVH38_RS14015	COG0210	DNA helicase
KVH38_RS14020	COG1272	protein, Hemolysin III
KVH38_RS14025	COG1414	Transcriptional regulator
KVH38_RS14035	COG1454	alcohol dehydrogenase
KVH38_RS14045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KVH38_RS14050	COG0366	Alpha amylase catalytic
KVH38_RS14065	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KVH38_RS14085	COG0251	oxidation-reduction process
KVH38_RS14090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KVH38_RS14100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KVH38_RS14105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KVH38_RS14125	COG1250	3-hydroxyacyl-CoA dehydrogenase
KVH38_RS14140	COG2003	Belongs to the UPF0758 family
KVH38_RS14145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KVH38_RS14150	COG0756	dUTP diphosphatase activity
KVH38_RS14160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KVH38_RS14175	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KVH38_RS14180	COG0708	Exodeoxyribonuclease III
KVH38_RS14190	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KVH38_RS14195	COG1561	YicC-like family, N-terminal region
KVH38_RS14205	COG1758	RNA polymerase activity
KVH38_RS14210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KVH38_RS14230	COG2080	2 iron, 2 sulfur cluster binding
KVH38_RS14250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KVH38_RS14270	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KVH38_RS14275	COG1704	LemA family
KVH38_RS14280	COG0583	DNA-binding transcription factor activity
KVH38_RS14285	COG0604	alcohol dehydrogenase
KVH38_RS14295	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS14300	COG0583	DNA-binding transcription factor activity
KVH38_RS14325	COG1620	l-lactate permease
KVH38_RS14330	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KVH38_RS14335	COG3193	protein, possibly involved in utilization of glycolate and propanediol
KVH38_RS14340	COG0247	lactate metabolic process
KVH38_RS14345	COG0277	FAD linked oxidase domain protein
KVH38_RS14350	COG0277	FAD linked oxidase domain protein
KVH38_RS14355	COG2186	Transcriptional regulator
KVH38_RS14360	COG3161	chorismate lyase activity
KVH38_RS14365	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KVH38_RS14380	COG1253	flavin adenine dinucleotide binding
KVH38_RS14390	COG0739	heme binding
KVH38_RS14410	COG0411	ABC transporter
KVH38_RS14420	COG0559	Belongs to the binding-protein-dependent transport system permease family
KVH38_RS14430	COG1192	Involved in chromosome partitioning
KVH38_RS14435	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KVH38_RS14440	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KVH38_RS14445	COG0730	response to heat
KVH38_RS14460	COG0494	nUDIX hydrolase
KVH38_RS14475	COG0702	epimerase
KVH38_RS14485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KVH38_RS14490	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KVH38_RS14510	COG0179	Fumarylacetoacetate (FAA) hydrolase
KVH38_RS14515	COG0277	FAD linked oxidase domain protein
KVH38_RS14520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KVH38_RS14545	COG2197	response regulator
KVH38_RS14585	COG0651	ATP synthesis coupled electron transport
KVH38_RS14590	COG0651	ATP synthesis coupled electron transport
KVH38_RS14610	COG1320	monovalent cation:proton antiporter activity
KVH38_RS14625	COG1966	Carbon starvation protein
KVH38_RS14640	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS14655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KVH38_RS14660	COG5001	Diguanylate cyclase
KVH38_RS14685	COG4807	Protein conserved in bacteria
KVH38_RS14690	COG2204	response regulator
KVH38_RS14730	COG4565	transcriptional regulatory protein
KVH38_RS14735	COG3290	protein histidine kinase activity
KVH38_RS14740	COG3493	citrate carrier protein
KVH38_RS14750	COG1217	gtp-binding protein TYPA
KVH38_RS14755	COG0301	tRNA thio-modification
KVH38_RS14755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KVH38_RS14775	COG3852	Histidine kinase
KVH38_RS14795	COG0243	molybdopterin cofactor binding
KVH38_RS14805	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KVH38_RS14815	COG0840	transmembrane signaling receptor activity
KVH38_RS14825	COG2226	methyltransferase
KVH38_RS14835	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KVH38_RS14840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KVH38_RS14845	COG0140	phosphoribosyl-ATP diphosphatase activity
KVH38_RS14850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KVH38_RS14855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KVH38_RS14880	COG1490	D-aminoacyl-tRNA deacylase activity
KVH38_RS14910	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KVH38_RS14915	COG0058	SHG alpha-glucan phosphorylase activity
KVH38_RS14930	COG1218	3'(2'),5'-bisphosphate nucleotidase
KVH38_RS14935	COG0494	nUDIX hydrolase
KVH38_RS14950	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KVH38_RS14965	COG1454	alcohol dehydrogenase
KVH38_RS14970	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS14975	COG1024	Enoyl-CoA hydratase
KVH38_RS14975	COG1250	3-hydroxyacyl-CoA dehydrogenase
KVH38_RS14985	COG1366	Belongs to the anti-sigma-factor antagonist family
KVH38_RS14990	COG1366	Belongs to the anti-sigma-factor antagonist family
KVH38_RS14995	COG2172	sigma factor antagonist activity
KVH38_RS15005	COG2205	protein histidine kinase activity
KVH38_RS15010	COG4191	Histidine kinase
KVH38_RS15010	COG0784	Response regulator, receiver
KVH38_RS15035	COG0667	Aldo Keto reductase
KVH38_RS15050	COG0840	transmembrane signaling receptor activity
KVH38_RS15055	COG0514	ATP-dependent DNA helicase (RecQ)
KVH38_RS15065	COG0778	Nitroreductase
KVH38_RS15075	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KVH38_RS15085	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KVH38_RS15090	COG4067	protein conserved in archaea
KVH38_RS15090	COG0189	ligase activity
KVH38_RS15095	COG0189	ligase activity
KVH38_RS15125	COG2194	sulfuric ester hydrolase activity
KVH38_RS15135	COG1192	Involved in chromosome partitioning
KVH38_RS15140	COG1215	transferase activity, transferring glycosyl groups
KVH38_RS15145	COG1215	transferase activity, transferring glycosyl groups
KVH38_RS15150	COG3118	belongs to the thioredoxin family
KVH38_RS15150	COG0457	Tetratricopeptide repeat
KVH38_RS15155	COG2183	response to ionizing radiation
KVH38_RS15165	COG2918	glutathione biosynthetic process
KVH38_RS15180	COG0306	phosphate transporter
KVH38_RS15185	COG1392	Phosphate transport regulator
KVH38_RS15215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KVH38_RS15225	COG2989	Protein conserved in bacteria
KVH38_RS15240	COG1764	response to oxidative stress
KVH38_RS15245	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KVH38_RS15300	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KVH38_RS15330	COG0732	type I restriction modification DNA specificity domain
KVH38_RS15335	COG1715	Restriction endonuclease
KVH38_RS15380	COG2814	Major facilitator Superfamily
KVH38_RS15385	COG0583	DNA-binding transcription factor activity
KVH38_RS15410	COG1116	anion transmembrane transporter activity
KVH38_RS15415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KVH38_RS15420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KVH38_RS15425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KVH38_RS15430	COG0431	NADPH-dependent FMN reductase
KVH38_RS15435	COG0450	alkyl hydroperoxide reductase
KVH38_RS15445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KVH38_RS15450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KVH38_RS15460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KVH38_RS15475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KVH38_RS15490	COG2175	clavaminate synthase activity
KVH38_RS15495	COG3829	transcription factor binding
KVH38_RS15505	COG5583	Uncharacterized small protein (DUF2292)
KVH38_RS15510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KVH38_RS15520	COG4208	sulfate ABC transporter
KVH38_RS15530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KVH38_RS15560	COG2205	protein histidine kinase activity
KVH38_RS15565	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KVH38_RS15565	COG1082	Xylose isomerase domain protein TIM barrel
KVH38_RS15575	COG0583	DNA-binding transcription factor activity
KVH38_RS15585	COG1301	dicarboxylic acid transport
KVH38_RS15595	COG1115	amino acid carrier protein
KVH38_RS15600	COG0252	asparaginase activity
KVH38_RS15615	COG2066	Belongs to the glutaminase family
KVH38_RS15630	COG0511	ligase activity, forming carbon-carbon bonds
KVH38_RS15630	COG5016	pyruvate
KVH38_RS15635	COG0439	Biotin carboxylase
KVH38_RS15640	COG0583	DNA-binding transcription factor activity
KVH38_RS15655	COG0837	glucose binding
KVH38_RS15655	COG1737	Transcriptional regulator
KVH38_RS15660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KVH38_RS15670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KVH38_RS15675	COG1917	Cupin 2, conserved barrel domain protein
KVH38_RS15680	COG5285	phytanoyl-CoA dioxygenase
KVH38_RS15685	COG0527	aspartate kinase activity
KVH38_RS15690	COG2841	Protein conserved in bacteria
KVH38_RS15695	COG0826	peptidase U32
KVH38_RS15705	COG0210	DNA helicase
KVH38_RS15710	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KVH38_RS15725	COG1764	response to oxidative stress
KVH38_RS15740	COG0437	4 iron, 4 sulfur cluster binding
KVH38_RS15745	COG2864	formate dehydrogenase
KVH38_RS15750	COG3058	Necessary for formate dehydrogenase activity
KVH38_RS15755	COG1921	L-seryl-tRNASec selenium transferase activity
KVH38_RS15760	COG3276	selenocysteine insertion sequence binding
KVH38_RS15785	COG0509	glycine decarboxylation via glycine cleavage system
KVH38_RS15795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KVH38_RS15800	COG0589	response to stress
KVH38_RS15810	COG4191	Histidine kinase
KVH38_RS15815	COG2204	response regulator
KVH38_RS15820	COG4941	Belongs to the sigma-70 factor family
KVH38_RS15825	COG3795	YCII-related domain
KVH38_RS15850	COG0784	Response regulator, receiver
KVH38_RS15850	COG4191	Histidine kinase
KVH38_RS15855	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS15860	COG2706	6-phosphogluconolactonase activity
KVH38_RS15900	COG0583	DNA-binding transcription factor activity
KVH38_RS15905	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KVH38_RS15975	COG2249	NAD(P)H dehydrogenase (quinone) activity
KVH38_RS15985	COG2207	Transcriptional regulator
KVH38_RS16055	COG1611	Belongs to the LOG family
KVH38_RS16070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KVH38_RS16075	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KVH38_RS16080	COG0318	PFAM AMP-dependent synthetase and ligase
KVH38_RS16100	COG2814	Major facilitator Superfamily
KVH38_RS16105	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS16110	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS16115	COG1024	Enoyl-CoA hydratase
KVH38_RS16115	COG1250	3-hydroxyacyl-CoA dehydrogenase
KVH38_RS16125	COG1012	belongs to the aldehyde dehydrogenase family
KVH38_RS16130	COG3909	cytochrome
KVH38_RS16135	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
KVH38_RS16180	COG0515	serine threonine protein kinase
KVH38_RS16215	COG0840	transmembrane signaling receptor activity
KVH38_RS16230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KVH38_RS16250	COG3052	prosthetic group binding
KVH38_RS16255	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KVH38_RS16265	COG4221	oxidoreductase activity
KVH38_RS16270	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KVH38_RS16285	COG2358	TRAP transporter, solute receptor (TAXI family
KVH38_RS16325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KVH38_RS16335	COG3360	Dodecin
KVH38_RS16340	COG0625	glutathione transferase activity
KVH38_RS16360	COG0737	Belongs to the 5'-nucleotidase family
KVH38_RS16375	COG3340	Belongs to the peptidase S51 family
KVH38_RS16380	COG1132	(ABC) transporter
KVH38_RS16420	COG2323	membrane
KVH38_RS16425	COG0583	DNA-binding transcription factor activity
KVH38_RS16460	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KVH38_RS16465	COG0339	signal peptide processing
KVH38_RS16495	COG0659	secondary active sulfate transmembrane transporter activity
KVH38_RS16505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KVH38_RS16510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KVH38_RS16515	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KVH38_RS16545	COG0109	protoheme IX farnesyltransferase activity
KVH38_RS16570	COG1595	DNA-templated transcription, initiation
KVH38_RS16585	COG0523	cobalamin synthesis protein
KVH38_RS16600	COG4251	negative regulation of phosphorylation
KVH38_RS16605	COG0784	Response regulator, receiver
KVH38_RS16650	COG1484	DNA-dependent DNA replication
KVH38_RS16685	COG3547	Transposase (IS116 IS110 IS902 family)
KVH38_RS16745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KVH38_RS16750	COG1349	DNA-binding transcription factor activity
KVH38_RS16760	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KVH38_RS16765	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KVH38_RS16770	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KVH38_RS16775	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KVH38_RS16780	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KVH38_RS16785	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KVH38_RS16790	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KVH38_RS16800	COG0356	it plays a direct role in the translocation of protons across the membrane
KVH38_RS16810	COG1475	DNA binding
KVH38_RS16815	COG1192	Involved in chromosome partitioning
KVH38_RS16820	COG0357	Ribosomal RNA small subunit methyltransferase G
KVH38_RS16825	COG0445	tRNA wobble uridine modification
KVH38_RS16830	COG1320	monovalent cation:proton antiporter activity
KVH38_RS16845	COG0651	ATP synthesis coupled electron transport
KVH38_RS16850	COG1006	Multisubunit Na H antiporter MnhC subunit
KVH38_RS16855	COG2111	Na H antiporter
KVH38_RS16860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KVH38_RS16860	COG2111	Na H antiporter
KVH38_RS16865	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KVH38_RS16870	COG0706	membrane insertase activity
KVH38_RS16875	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KVH38_RS16880	COG0594	ribonuclease P activity
KVH38_RS16885	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KVH38_RS16890	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KVH38_RS16900	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KVH38_RS16915	COG3706	GGDEF domain
KVH38_RS16930	COG0751	glycine-tRNA ligase activity
KVH38_RS16940	COG2818	Glycosylase
KVH38_RS16960	COG1126	abc transporter atp-binding protein
KVH38_RS16965	COG0765	amino acid transport
KVH38_RS16970	COG0765	amino acid transport
KVH38_RS16975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KVH38_RS16980	COG0569	domain protein
KVH38_RS16985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KVH38_RS16990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KVH38_RS16995	COG0242	peptide deformylase activity
KVH38_RS17005	COG0758	DNA mediated transformation
KVH38_RS17010	COG0009	L-threonylcarbamoyladenylate synthase
KVH38_RS17020	COG0408	coproporphyrinogen oxidase activity
KVH38_RS17025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KVH38_RS17040	COG1686	Belongs to the peptidase S11 family
KVH38_RS17080	COG2011	ABC-type metal ion transport system permease component
KVH38_RS17095	COG1451	nucleotide metabolic process
KVH38_RS17100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KVH38_RS17105	COG1121	(ABC) transporter
KVH38_RS17110	COG0735	belongs to the Fur family
KVH38_RS17120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KVH38_RS17125	COG1012	belongs to the aldehyde dehydrogenase family
KVH38_RS17145	COG0745	RESPONSE REGULATOR receiver
KVH38_RS17150	COG5002	protein histidine kinase activity
KVH38_RS17160	COG0745	RESPONSE REGULATOR receiver
KVH38_RS17165	COG5002	protein histidine kinase activity
KVH38_RS17170	COG0745	RESPONSE REGULATOR receiver
KVH38_RS17175	COG4191	Histidine kinase
KVH38_RS17185	COG3706	GGDEF domain
KVH38_RS17195	COG2957	Belongs to the agmatine deiminase family
KVH38_RS17210	COG0174	glutamine synthetase
KVH38_RS17215	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KVH38_RS17220	COG0174	glutamine synthetase
KVH38_RS17245	COG3842	ATPase activity
KVH38_RS17250	COG1176	ABC-type spermidine putrescine transport system, permease component I
KVH38_RS17255	COG1177	transmembrane transport
KVH38_RS17325	COG0842	Transport permease protein
KVH38_RS17330	COG1129	ABC transporter
KVH38_RS17330	COG0842	Transport permease protein
KVH38_RS17335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KVH38_RS17350	COG1127	ABC transporter
KVH38_RS17355	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KVH38_RS17360	COG0753	catalase activity
KVH38_RS17365	COG2010	Cytochrome c
KVH38_RS17390	COG2204	response regulator
KVH38_RS17445	COG0676	glucose-6-phosphate 1-epimerase activity
KVH38_RS17480	COG1525	nuclease
KVH38_RS17490	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KVH38_RS17495	COG1194	a g-specific adenine glycosylase
KVH38_RS17510	COG1116	anion transmembrane transporter activity
KVH38_RS17520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KVH38_RS17525	COG3707	response regulator
KVH38_RS17530	COG0131	Imidazoleglycerol-phosphate dehydratase
KVH38_RS17545	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KVH38_RS17550	COG0107	imidazoleglycerol-phosphate synthase activity
KVH38_RS17565	COG2861	carbohydrate metabolic process
KVH38_RS17570	COG0793	Belongs to the peptidase S41A family
KVH38_RS17575	COG4942	peptidase
KVH38_RS17580	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KVH38_RS17585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KVH38_RS17595	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KVH38_RS17620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KVH38_RS17640	COG3079	Belongs to the UPF0149 family
KVH38_RS17645	COG0006	proline dipeptidase activity
KVH38_RS17650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KVH38_RS17660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KVH38_RS17670	COG1178	ABC-type Fe3 transport system permease component
KVH38_RS17685	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KVH38_RS17685	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KVH38_RS17690	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KVH38_RS17715	COG3023	N-Acetylmuramoyl-L-alanine amidase
KVH38_RS17725	COG5002	protein histidine kinase activity
KVH38_RS17730	COG2204	response regulator
KVH38_RS17750	COG0700	Nucleoside recognition
KVH38_RS17760	COG2358	TRAP transporter, solute receptor (TAXI family
KVH38_RS17765	COG0840	transmembrane signaling receptor activity
KVH38_RS17775	COG0840	transmembrane signaling receptor activity
KVH38_RS17780	COG2203	Gaf domain
KVH38_RS17780	COG3706	GGDEF domain
KVH38_RS17780	COG4251	negative regulation of phosphorylation
KVH38_RS17780	COG5001	Diguanylate cyclase
KVH38_RS17815	COG3180	Ammonia monooxygenase
KVH38_RS17830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KVH38_RS17835	COG1074	ATP-dependent DNA helicase activity
KVH38_RS17840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KVH38_RS17855	COG3706	GGDEF domain
KVH38_RS17855	COG4251	negative regulation of phosphorylation
KVH38_RS17855	COG5001	Diguanylate cyclase
KVH38_RS17855	COG2203	Gaf domain
KVH38_RS17860	COG1607	acyl-coa hydrolase
KVH38_RS17875	COG0573	inorganic phosphate transmembrane transporter activity
KVH38_RS17880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KVH38_RS17885	COG0704	Plays a role in the regulation of phosphate uptake
KVH38_RS17900	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KVH38_RS17910	COG0584	glycerophosphoryl diester phosphodiesterase
KVH38_RS17940	COG0129	dihydroxy-acid dehydratase activity
KVH38_RS17955	COG0693	protein deglycase activity
KVH38_RS17965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KVH38_RS17985	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KVH38_RS17995	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KVH38_RS18015	COG0429	hydrolase of the alpha beta-hydrolase fold
KVH38_RS18025	COG0742	ribosomal rna small subunit methyltransferase
KVH38_RS18030	COG0612	Peptidase, M16
KVH38_RS18035	COG0612	Peptidase, M16
KVH38_RS18040	COG0552	protein localization to endoplasmic reticulum
KVH38_RS18045	COG2884	Cell division ATP-binding protein ftsE
KVH38_RS18050	COG2177	Part of the ABC transporter FtsEX involved in
KVH38_RS18070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KVH38_RS18075	COG2363	Small membrane protein
KVH38_RS18085	COG2022	thiamine diphosphate biosynthetic process
KVH38_RS18090	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KVH38_RS18105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KVH38_RS18130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KVH38_RS18135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KVH38_RS18145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KVH38_RS18145	COG2813	Specifically methylates the guanine in position
KVH38_RS18150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KVH38_RS18205	COG0540	Belongs to the ATCase OTCase family
KVH38_RS18220	COG1678	Uncharacterized ACR, COG1678
KVH38_RS18260	COG2198	Histidine kinase
KVH38_RS18260	COG0784	Response regulator, receiver
KVH38_RS18260	COG0643	Histidine kinase
KVH38_RS18265	COG2201	protein-glutamate methylesterase activity
KVH38_RS18275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KVH38_RS18285	COG3038	cytochrome b561
KVH38_RS18290	COG2353	YceI-like domain
KVH38_RS18295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KVH38_RS18310	COG0513	Belongs to the DEAD box helicase family
KVH38_RS18315	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KVH38_RS18320	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KVH38_RS18340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KVH38_RS18345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KVH38_RS18350	COG1131	(ABC) transporter
KVH38_RS18355	COG0842	Transport permease protein
KVH38_RS18365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KVH38_RS18370	COG2226	methyltransferase
KVH38_RS18380	COG2175	clavaminate synthase activity
KVH38_RS18385	COG0583	DNA-binding transcription factor activity
KVH38_RS18390	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KVH38_RS18395	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KVH38_RS18400	COG0126	phosphoglycerate kinase activity
KVH38_RS18415	COG0191	fructose-bisphosphate aldolase activity
KVH38_RS18455	COG2081	HI0933 family
KVH38_RS18465	COG1289	transmembrane transporter activity
KVH38_RS18470	COG0513	Belongs to the DEAD box helicase family
KVH38_RS18485	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KVH38_RS18515	COG0840	transmembrane signaling receptor activity
KVH38_RS18565	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KVH38_RS18575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KVH38_RS18580	COG1609	Transcriptional regulator
KVH38_RS18595	COG1917	Cupin 2, conserved barrel domain protein
KVH38_RS18595	COG4977	sequence-specific DNA binding
KVH38_RS18605	COG0583	DNA-binding transcription factor activity
KVH38_RS18635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KVH38_RS18640	COG1012	belongs to the aldehyde dehydrogenase family
KVH38_RS18650	COG2721	sulfolactate sulfo-lyase activity
KVH38_RS18660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KVH38_RS18670	COG4774	siderophore transport
KVH38_RS18700	COG0330	HflC and HflK could
KVH38_RS18730	COG0784	Response regulator, receiver
KVH38_RS18730	COG2198	Histidine kinase
KVH38_RS18730	COG2205	protein histidine kinase activity
KVH38_RS18735	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KVH38_RS18745	COG5002	protein histidine kinase activity
KVH38_RS18750	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KVH38_RS18755	COG1196	nuclear chromosome segregation
KVH38_RS18755	COG3264	Mechanosensitive ion channel
KVH38_RS18760	COG3263	regulation of cellular component size
KVH38_RS18765	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS18775	COG1304	FMN binding
KVH38_RS18810	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KVH38_RS18815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KVH38_RS18820	COG1040	competence protein
KVH38_RS18825	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KVH38_RS18830	COG0156	8-amino-7-oxononanoate synthase activity
KVH38_RS18835	COG1073	alpha beta
KVH38_RS18835	COG2226	methyltransferase
KVH38_RS18855	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS18860	COG3344	reverse transcriptase
KVH38_RS18865	COG3706	GGDEF domain
KVH38_RS18870	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS18875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KVH38_RS18900	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KVH38_RS18910	COG0859	PFAM glycosyl transferase family 9
KVH38_RS18915	COG0859	PFAM glycosyl transferase family 9
KVH38_RS18920	COG0438	transferase activity, transferring glycosyl groups
KVH38_RS18945	COG2192	nodulation
KVH38_RS18950	COG0438	transferase activity, transferring glycosyl groups
KVH38_RS18965	COG0438	transferase activity, transferring glycosyl groups
KVH38_RS18985	COG1132	(ABC) transporter
KVH38_RS18990	COG3642	lipopolysaccharide core region biosynthetic process
KVH38_RS19005	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KVH38_RS19005	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KVH38_RS19025	COG0667	Aldo Keto reductase
KVH38_RS19040	COG1519	Transferase
KVH38_RS19045	COG1538	Outer membrane efflux protein
KVH38_RS19050	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KVH38_RS19060	COG0494	nUDIX hydrolase
KVH38_RS19070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KVH38_RS19075	COG3150	esterase
KVH38_RS19110	COG0560	Phosphoserine phosphatase
KVH38_RS19110	COG3830	Belongs to the UPF0237 family
KVH38_RS19115	COG1063	alcohol dehydrogenase
KVH38_RS19120	COG2200	EAL domain
KVH38_RS19130	COG0688	phosphatidylethanolamine metabolic process
KVH38_RS19145	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KVH38_RS19150	COG1360	Flagellar Motor Protein
KVH38_RS19155	COG1162	GTPase activity
KVH38_RS19165	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KVH38_RS19170	COG0702	epimerase
KVH38_RS19190	COG1346	cytolysis
KVH38_RS19200	COG0586	Pfam SNARE associated Golgi protein
KVH38_RS19205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KVH38_RS19210	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KVH38_RS19220	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KVH38_RS19225	COG0768	penicillin binding
KVH38_RS19230	COG0772	Belongs to the SEDS family
KVH38_RS19235	COG2951	lytic endotransglycosylase activity
KVH38_RS19245	COG1686	Belongs to the peptidase S11 family
KVH38_RS19250	COG2921	Belongs to the UPF0250 family
KVH38_RS19255	COG0321	lipoyl(octanoyl) transferase activity
KVH38_RS19260	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KVH38_RS19270	COG2951	lytic endotransglycosylase activity
KVH38_RS19275	COG3036	rescue of stalled ribosome
KVH38_RS19290	COG0495	leucyl-tRNA aminoacylation
KVH38_RS19305	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KVH38_RS19310	COG4535	Mg2 and Co2 transporter CorC
KVH38_RS19315	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KVH38_RS19320	COG1702	phosphate starvation-inducible protein PhoH
KVH38_RS19325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KVH38_RS19340	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KVH38_RS19345	COG0352	thiamine-phosphate diphosphorylase activity
KVH38_RS19350	COG0351	phosphomethylpyrimidine kinase
KVH38_RS19350	COG0352	thiamine-phosphate diphosphorylase activity
KVH38_RS19355	COG3437	response regulator, receiver
KVH38_RS19355	COG3850	Histidine kinase
KVH38_RS19355	COG2205	protein histidine kinase activity
KVH38_RS19355	COG4999	Histidine kinase
KVH38_RS19360	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS19375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KVH38_RS19380	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KVH38_RS19395	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KVH38_RS19400	COG0830	nickel cation binding
KVH38_RS19405	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KVH38_RS19420	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KVH38_RS19425	COG2814	Major facilitator Superfamily
KVH38_RS19435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KVH38_RS19445	COG1953	Uracil, thiamine, allantoin
KVH38_RS19450	COG0804	urea catabolic process
KVH38_RS19455	COG0832	Belongs to the urease beta subunit family
KVH38_RS19465	COG0831	urea catabolic process
KVH38_RS19470	COG0829	nickel cation binding
KVH38_RS19520	COG1522	sequence-specific DNA binding
KVH38_RS19540	COG1643	Atp-dependent helicase
KVH38_RS19550	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS19570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KVH38_RS19575	COG0142	geranyltranstransferase activity
KVH38_RS19580	COG1722	exodeoxyribonuclease VII activity
KVH38_RS19605	COG3486	L-lysine 6-monooxygenase (NADPH) activity
KVH38_RS19610	COG0076	glutamate decarboxylase activity
KVH38_RS19620	COG5001	Diguanylate cyclase
KVH38_RS19620	COG3300	MHYT domain
KVH38_RS19630	COG2201	protein-glutamate methylesterase activity
KVH38_RS19640	COG0835	chemotaxis
KVH38_RS19645	COG0840	transmembrane signaling receptor activity
KVH38_RS19650	COG0643	Histidine kinase
KVH38_RS19650	COG2198	Histidine kinase
KVH38_RS19660	COG0745	RESPONSE REGULATOR receiver
KVH38_RS19670	COG3851	Histidine kinase
KVH38_RS19675	COG2197	response regulator
KVH38_RS19695	COG3228	Belongs to the MtfA family
KVH38_RS19715	COG4303	Ethanolamine ammonia lyase large subunit
KVH38_RS19720	COG0531	amino acid
KVH38_RS19730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KVH38_RS19755	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KVH38_RS19755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KVH38_RS19760	COG0802	atpase or kinase
KVH38_RS19765	COG0860	N-Acetylmuramoyl-L-alanine amidase
KVH38_RS19770	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KVH38_RS19775	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KVH38_RS19780	COG1923	regulation of RNA biosynthetic process
KVH38_RS19785	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KVH38_RS19790	COG0330	HflC and HflK could
KVH38_RS19795	COG0330	HflC and HflK could
KVH38_RS19800	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KVH38_RS19805	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KVH38_RS19825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KVH38_RS19830	COG0784	Response regulator, receiver
KVH38_RS19830	COG4191	Histidine kinase
KVH38_RS19835	COG0360	Binds together with S18 to 16S ribosomal RNA
KVH38_RS19840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KVH38_RS19850	COG0359	binds to the 23S rRNA
KVH38_RS19855	COG0305	Participates in initiation and elongation during chromosome replication
KVH38_RS19860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KVH38_RS19865	COG3300	MHYT domain
KVH38_RS19865	COG5001	Diguanylate cyclase
KVH38_RS19940	COG1252	NADH dehydrogenase
KVH38_RS19965	COG2945	thiolester hydrolase activity
KVH38_RS19970	COG0180	Tryptophanyl-tRNA synthetase
KVH38_RS19975	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KVH38_RS19985	COG1515	deoxyribonuclease V activity
KVH38_RS19990	COG3023	N-Acetylmuramoyl-L-alanine amidase
KVH38_RS20000	COG0840	transmembrane signaling receptor activity
KVH38_RS20005	COG0084	hydrolase, TatD family'
KVH38_RS20015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KVH38_RS20015	COG2169	Transcriptional regulator
KVH38_RS20030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KVH38_RS20045	COG0840	transmembrane signaling receptor activity
KVH38_RS20060	COG2217	Heavy metal translocating P-type atpase
KVH38_RS20075	COG2814	Major facilitator Superfamily
KVH38_RS20085	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KVH38_RS20115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KVH38_RS20120	COG0778	Nitroreductase
KVH38_RS20125	COG0596	Alpha beta hydrolase
KVH38_RS20130	COG0251	oxidation-reduction process
KVH38_RS20135	COG1335	isochorismatase
KVH38_RS20140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KVH38_RS20145	COG1309	transcriptional regulator
KVH38_RS20150	COG1917	Cupin 2, conserved barrel domain protein
KVH38_RS20150	COG2207	Transcriptional regulator
KVH38_RS20205	COG3845	ABC transporter
KVH38_RS20215	COG1079	Belongs to the binding-protein-dependent transport system permease family
KVH38_RS20235	COG1278	Cold shock
KVH38_RS20240	COG2824	Alkylphosphonate utilization operon protein PhnA
KVH38_RS20245	COG1607	acyl-coa hydrolase
KVH38_RS20255	COG0402	S-adenosylhomocysteine deaminase activity
KVH38_RS20260	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KVH38_RS20275	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
KVH38_RS20290	COG2154	pterin-4-alpha-carbinolamine dehydratase
KVH38_RS20310	COG1760	l-serine dehydratase
KVH38_RS20315	COG0492	ferredoxin-NADP+ reductase activity
KVH38_RS20330	COG3189	MarR family transcriptional regulator
KVH38_RS20345	COG1960	acyl-CoA dehydrogenase activity
KVH38_RS20350	COG0348	domain, Protein
KVH38_RS20350	COG3901	Regulator of nitric oxide reductase transcription
KVH38_RS20355	COG4263	nitrous-oxide reductase activity
KVH38_RS20370	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KVH38_RS20390	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS20440	COG4968	Prepilin-type N-terminal cleavage methylation domain
KVH38_RS20450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KVH38_RS20450	COG1648	precorrin-2 dehydrogenase activity
KVH38_RS20455	COG0535	radical SAM domain protein
KVH38_RS20465	COG1845	cytochrome c oxidase, subunit III
KVH38_RS20470	COG0714	Associated with various cellular activities
KVH38_RS20475	COG2010	Cytochrome c
KVH38_RS20495	COG2010	Cytochrome c
KVH38_RS20500	COG3391	amine dehydrogenase activity
KVH38_RS20525	COG2010	Cytochrome c
KVH38_RS20530	COG3256	nitric oxide reductase
KVH38_RS20560	COG3604	Transcriptional regulator
KVH38_RS20570	COG0826	peptidase U32
KVH38_RS20575	COG0826	peptidase U32
KVH38_RS20580	COG3154	lipid carrier protein
KVH38_RS20630	COG2814	Major facilitator Superfamily
KVH38_RS20650	COG1737	Transcriptional regulator
KVH38_RS20665	COG0800	Aldolase
KVH38_RS20675	COG4989	oxidoreductase activity
KVH38_RS20690	COG4580	involved in the transport of maltose and maltodextrins
KVH38_RS20705	COG0366	Alpha amylase catalytic
KVH38_RS20770	COG3387	PFAM Glycoside hydrolase 15-related
KVH38_RS20880	COG0616	signal peptide processing
KVH38_RS20880	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KVH38_RS21090	COG1074	ATP-dependent DNA helicase activity
KVH38_RS21120	COG1192	Involved in chromosome partitioning
KVH38_RS21150	COG3436	PFAM IS66 Orf2 family protein
KVH38_RS21155	COG4372	Transposase
KVH38_RS21160	COG3012	SEC-C Motif Domain Protein
KVH38_RS21190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KVH38_RS21260	COG3039	Transposase
KVH38_RS21290	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS21295	COG0318	PFAM AMP-dependent synthetase and ligase
KVH38_RS21315	COG4372	Transposase
KVH38_RS21390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KVH38_RS21400	COG1061	Type III restriction enzyme res subunit
KVH38_RS21485	COG4372	Transposase
KVH38_RS21510	COG2963	transposase activity
KVH38_RS21555	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KVH38_RS21585	COG3039	Transposase
KVH38_RS21590	COG4221	oxidoreductase activity
KVH38_RS21595	COG3387	PFAM Glycoside hydrolase 15-related
KVH38_RS21625	COG1484	DNA-dependent DNA replication
KVH38_RS21640	COG4372	Transposase
KVH38_RS21665	COG1404	Belongs to the peptidase S8 family
KVH38_RS21670	COG0464	growth
KVH38_RS21675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KVH38_RS21715	COG0629	single-stranded DNA binding
KVH38_RS21810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KVH38_RS21820	COG0681	Belongs to the peptidase S26 family
KVH38_RS21935	COG1570	exodeoxyribonuclease VII activity
KVH38_RS21965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KVH38_RS22000	COG3387	PFAM Glycoside hydrolase 15-related
KVH38_RS22005	COG1028	Short-chain dehydrogenase reductase Sdr
KVH38_RS22100	COG4644	lycopene metabolic process
KVH38_RS22220	COG1442	glycosyl transferase family 8
KVH38_RS22270	COG2814	Major facilitator Superfamily
KVH38_RS22310	COG1428	Deoxynucleoside kinase
KVH38_RS22325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KVH38_RS22330	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KVH38_RS22340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KVH38_RS22425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KVH38_RS22490	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KVH38_RS22495	COG1397	ADP-ribosylglycohydrolase
KVH38_RS22585	COG1597	lipid kinase activity
KVH38_RS22590	COG1597	lipid kinase activity
KVH38_RS22595	COG1597	lipid kinase activity
KVH38_RS22600	COG1309	transcriptional regulator
KVH38_RS22605	COG1309	transcriptional regulator
KVH38_RS22630	COG0768	penicillin binding