locus-tag	class	description
LQF05_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LQF05_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LQF05_RS00030	COG3706	GGDEF domain
LQF05_RS00045	COG0751	glycine-tRNA ligase activity
LQF05_RS00055	COG2818	Glycosylase
LQF05_RS00075	COG1126	abc transporter atp-binding protein
LQF05_RS00080	COG0765	amino acid transport
LQF05_RS00085	COG0765	amino acid transport
LQF05_RS00090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LQF05_RS00095	COG0569	domain protein
LQF05_RS00100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LQF05_RS00105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LQF05_RS00110	COG0242	peptide deformylase activity
LQF05_RS00120	COG0758	DNA mediated transformation
LQF05_RS00125	COG0009	L-threonylcarbamoyladenylate synthase
LQF05_RS00135	COG0408	coproporphyrinogen oxidase activity
LQF05_RS00140	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LQF05_RS00155	COG1686	Belongs to the peptidase S11 family
LQF05_RS00195	COG2011	ABC-type metal ion transport system permease component
LQF05_RS00210	COG1451	nucleotide metabolic process
LQF05_RS00215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LQF05_RS00220	COG1121	(ABC) transporter
LQF05_RS00225	COG0735	belongs to the Fur family
LQF05_RS00235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LQF05_RS00240	COG1012	belongs to the aldehyde dehydrogenase family
LQF05_RS00260	COG0745	RESPONSE REGULATOR receiver
LQF05_RS00265	COG5002	protein histidine kinase activity
LQF05_RS00275	COG0745	RESPONSE REGULATOR receiver
LQF05_RS00280	COG5002	protein histidine kinase activity
LQF05_RS00285	COG0745	RESPONSE REGULATOR receiver
LQF05_RS00290	COG4191	Histidine kinase
LQF05_RS00300	COG3706	GGDEF domain
LQF05_RS00310	COG2957	Belongs to the agmatine deiminase family
LQF05_RS00325	COG0174	glutamine synthetase
LQF05_RS00330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LQF05_RS00335	COG0174	glutamine synthetase
LQF05_RS00360	COG3842	ATPase activity
LQF05_RS00365	COG1176	ABC-type spermidine putrescine transport system, permease component I
LQF05_RS00370	COG1177	transmembrane transport
LQF05_RS00440	COG0842	Transport permease protein
LQF05_RS00445	COG0842	Transport permease protein
LQF05_RS00445	COG1129	ABC transporter
LQF05_RS00450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQF05_RS00465	COG1127	ABC transporter
LQF05_RS00470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LQF05_RS00475	COG0753	catalase activity
LQF05_RS00480	COG2010	Cytochrome c
LQF05_RS00495	COG3179	chitinase
LQF05_RS00505	COG2204	response regulator
LQF05_RS00560	COG0676	glucose-6-phosphate 1-epimerase activity
LQF05_RS00595	COG1525	nuclease
LQF05_RS00605	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LQF05_RS00610	COG1194	a g-specific adenine glycosylase
LQF05_RS00625	COG1116	anion transmembrane transporter activity
LQF05_RS00635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LQF05_RS00640	COG3707	response regulator
LQF05_RS00645	COG0131	Imidazoleglycerol-phosphate dehydratase
LQF05_RS00660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LQF05_RS00665	COG0107	imidazoleglycerol-phosphate synthase activity
LQF05_RS00680	COG2861	carbohydrate metabolic process
LQF05_RS00685	COG0793	Belongs to the peptidase S41A family
LQF05_RS00690	COG4942	peptidase
LQF05_RS00695	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LQF05_RS00700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LQF05_RS00710	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LQF05_RS00735	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LQF05_RS00755	COG3079	Belongs to the UPF0149 family
LQF05_RS00760	COG0006	proline dipeptidase activity
LQF05_RS00765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LQF05_RS00775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LQF05_RS00785	COG1178	ABC-type Fe3 transport system permease component
LQF05_RS00800	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LQF05_RS00800	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LQF05_RS00805	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LQF05_RS00830	COG3023	N-Acetylmuramoyl-L-alanine amidase
LQF05_RS00840	COG5002	protein histidine kinase activity
LQF05_RS00845	COG2204	response regulator
LQF05_RS00865	COG0700	Nucleoside recognition
LQF05_RS00875	COG2358	TRAP transporter, solute receptor (TAXI family
LQF05_RS00880	COG0840	transmembrane signaling receptor activity
LQF05_RS00890	COG0840	transmembrane signaling receptor activity
LQF05_RS00895	COG3706	GGDEF domain
LQF05_RS00895	COG4251	negative regulation of phosphorylation
LQF05_RS00895	COG5001	Diguanylate cyclase
LQF05_RS00895	COG2203	Gaf domain
LQF05_RS00930	COG3180	Ammonia monooxygenase
LQF05_RS00945	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LQF05_RS00950	COG1074	ATP-dependent DNA helicase activity
LQF05_RS00955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LQF05_RS00970	COG2203	Gaf domain
LQF05_RS00970	COG3706	GGDEF domain
LQF05_RS00970	COG5001	Diguanylate cyclase
LQF05_RS00970	COG4251	negative regulation of phosphorylation
LQF05_RS00975	COG1607	acyl-coa hydrolase
LQF05_RS00990	COG0573	inorganic phosphate transmembrane transporter activity
LQF05_RS00995	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LQF05_RS01000	COG0704	Plays a role in the regulation of phosphate uptake
LQF05_RS01015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LQF05_RS01025	COG0584	glycerophosphoryl diester phosphodiesterase
LQF05_RS01055	COG0129	dihydroxy-acid dehydratase activity
LQF05_RS01065	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LQF05_RS01070	COG0693	protein deglycase activity
LQF05_RS01080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LQF05_RS01100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LQF05_RS01105	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LQF05_RS01110	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LQF05_RS01140	COG0742	ribosomal rna small subunit methyltransferase
LQF05_RS01145	COG0612	Peptidase, M16
LQF05_RS01150	COG0612	Peptidase, M16
LQF05_RS01155	COG0552	protein localization to endoplasmic reticulum
LQF05_RS01160	COG2884	Cell division ATP-binding protein ftsE
LQF05_RS01165	COG2177	Part of the ABC transporter FtsEX involved in
LQF05_RS01185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LQF05_RS01190	COG2363	Small membrane protein
LQF05_RS01200	COG2022	thiamine diphosphate biosynthetic process
LQF05_RS01205	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LQF05_RS01220	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LQF05_RS01245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LQF05_RS01250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LQF05_RS01260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LQF05_RS01260	COG2813	Specifically methylates the guanine in position
LQF05_RS01265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LQF05_RS01320	COG0540	Belongs to the ATCase OTCase family
LQF05_RS01335	COG1678	Uncharacterized ACR, COG1678
LQF05_RS01375	COG0643	Histidine kinase
LQF05_RS01375	COG0784	Response regulator, receiver
LQF05_RS01375	COG2198	Histidine kinase
LQF05_RS01380	COG2201	protein-glutamate methylesterase activity
LQF05_RS01390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LQF05_RS01400	COG3038	cytochrome b561
LQF05_RS01405	COG2353	YceI-like domain
LQF05_RS01410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQF05_RS01425	COG0513	Belongs to the DEAD box helicase family
LQF05_RS01430	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LQF05_RS01435	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LQF05_RS01455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LQF05_RS01460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LQF05_RS01465	COG1131	(ABC) transporter
LQF05_RS01470	COG0842	Transport permease protein
LQF05_RS01480	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LQF05_RS01485	COG2226	methyltransferase
LQF05_RS01495	COG2175	clavaminate synthase activity
LQF05_RS01500	COG0583	DNA-binding transcription factor activity
LQF05_RS01505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LQF05_RS01510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LQF05_RS01515	COG0126	phosphoglycerate kinase activity
LQF05_RS01530	COG0191	fructose-bisphosphate aldolase activity
LQF05_RS01570	COG2081	HI0933 family
LQF05_RS01580	COG1289	transmembrane transporter activity
LQF05_RS01585	COG0513	Belongs to the DEAD box helicase family
LQF05_RS01600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LQF05_RS01665	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LQF05_RS01675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LQF05_RS01680	COG1609	Transcriptional regulator
LQF05_RS01695	COG4977	sequence-specific DNA binding
LQF05_RS01695	COG1917	Cupin 2, conserved barrel domain protein
LQF05_RS01710	COG0583	DNA-binding transcription factor activity
LQF05_RS01740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LQF05_RS01745	COG1012	belongs to the aldehyde dehydrogenase family
LQF05_RS01755	COG2721	sulfolactate sulfo-lyase activity
LQF05_RS01770	COG4774	siderophore transport
LQF05_RS01800	COG0330	HflC and HflK could
LQF05_RS01830	COG0784	Response regulator, receiver
LQF05_RS01830	COG2198	Histidine kinase
LQF05_RS01830	COG2205	protein histidine kinase activity
LQF05_RS01835	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LQF05_RS01845	COG5002	protein histidine kinase activity
LQF05_RS01850	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LQF05_RS01855	COG3264	Mechanosensitive ion channel
LQF05_RS01855	COG1196	nuclear chromosome segregation
LQF05_RS01860	COG3263	regulation of cellular component size
LQF05_RS01865	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS01875	COG1304	FMN binding
LQF05_RS01910	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LQF05_RS01915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LQF05_RS01920	COG1040	competence protein
LQF05_RS01925	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LQF05_RS01930	COG0156	8-amino-7-oxononanoate synthase activity
LQF05_RS01935	COG1073	alpha beta
LQF05_RS01935	COG2226	methyltransferase
LQF05_RS01955	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS01960	COG3706	GGDEF domain
LQF05_RS01965	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS01970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LQF05_RS01995	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LQF05_RS02005	COG0859	PFAM glycosyl transferase family 9
LQF05_RS02010	COG0859	PFAM glycosyl transferase family 9
LQF05_RS02015	COG0438	transferase activity, transferring glycosyl groups
LQF05_RS02040	COG2192	nodulation
LQF05_RS02045	COG0438	transferase activity, transferring glycosyl groups
LQF05_RS02080	COG1132	(ABC) transporter
LQF05_RS02095	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LQF05_RS02095	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LQF05_RS02105	COG0667	Aldo Keto reductase
LQF05_RS02120	COG1519	Transferase
LQF05_RS02125	COG1538	Outer membrane efflux protein
LQF05_RS02130	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LQF05_RS02140	COG0494	nUDIX hydrolase
LQF05_RS02150	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LQF05_RS02155	COG3150	esterase
LQF05_RS02190	COG3830	Belongs to the UPF0237 family
LQF05_RS02190	COG0560	Phosphoserine phosphatase
LQF05_RS02195	COG1063	alcohol dehydrogenase
LQF05_RS02200	COG2200	EAL domain
LQF05_RS02210	COG0688	phosphatidylethanolamine metabolic process
LQF05_RS02225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LQF05_RS02230	COG1360	Flagellar Motor Protein
LQF05_RS02235	COG1162	GTPase activity
LQF05_RS02245	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LQF05_RS02250	COG0702	epimerase
LQF05_RS02270	COG1346	cytolysis
LQF05_RS02280	COG0586	Pfam SNARE associated Golgi protein
LQF05_RS02285	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LQF05_RS02290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LQF05_RS02300	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LQF05_RS02305	COG0768	penicillin binding
LQF05_RS02310	COG0772	Belongs to the SEDS family
LQF05_RS02315	COG2951	lytic endotransglycosylase activity
LQF05_RS02325	COG1686	Belongs to the peptidase S11 family
LQF05_RS02330	COG2921	Belongs to the UPF0250 family
LQF05_RS02335	COG0321	lipoyl(octanoyl) transferase activity
LQF05_RS02340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LQF05_RS02350	COG2951	lytic endotransglycosylase activity
LQF05_RS02355	COG3036	rescue of stalled ribosome
LQF05_RS02370	COG0495	leucyl-tRNA aminoacylation
LQF05_RS02385	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LQF05_RS02390	COG4535	Mg2 and Co2 transporter CorC
LQF05_RS02395	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LQF05_RS02400	COG1702	phosphate starvation-inducible protein PhoH
LQF05_RS02405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LQF05_RS02420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LQF05_RS02425	COG0352	thiamine-phosphate diphosphorylase activity
LQF05_RS02430	COG0352	thiamine-phosphate diphosphorylase activity
LQF05_RS02430	COG0351	phosphomethylpyrimidine kinase
LQF05_RS02435	COG2205	protein histidine kinase activity
LQF05_RS02435	COG3850	Histidine kinase
LQF05_RS02435	COG3437	response regulator, receiver
LQF05_RS02435	COG4999	Histidine kinase
LQF05_RS02440	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS02450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LQF05_RS02455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LQF05_RS02460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LQF05_RS02475	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LQF05_RS02480	COG0830	nickel cation binding
LQF05_RS02485	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LQF05_RS02500	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LQF05_RS02505	COG2814	Major facilitator Superfamily
LQF05_RS02515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LQF05_RS02525	COG1953	Uracil, thiamine, allantoin
LQF05_RS02530	COG0804	urea catabolic process
LQF05_RS02535	COG0832	Belongs to the urease beta subunit family
LQF05_RS02545	COG0831	urea catabolic process
LQF05_RS02550	COG0829	nickel cation binding
LQF05_RS02600	COG1522	sequence-specific DNA binding
LQF05_RS02620	COG1643	Atp-dependent helicase
LQF05_RS02630	COG4221	oxidoreductase activity
LQF05_RS02650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LQF05_RS02655	COG0142	geranyltranstransferase activity
LQF05_RS02660	COG1722	exodeoxyribonuclease VII activity
LQF05_RS02685	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LQF05_RS02690	COG0076	glutamate decarboxylase activity
LQF05_RS02700	COG5001	Diguanylate cyclase
LQF05_RS02700	COG3300	MHYT domain
LQF05_RS02710	COG2201	protein-glutamate methylesterase activity
LQF05_RS02720	COG0835	chemotaxis
LQF05_RS02725	COG0840	transmembrane signaling receptor activity
LQF05_RS02730	COG0643	Histidine kinase
LQF05_RS02730	COG2198	Histidine kinase
LQF05_RS02740	COG0745	RESPONSE REGULATOR receiver
LQF05_RS02750	COG3851	Histidine kinase
LQF05_RS02755	COG2197	response regulator
LQF05_RS02775	COG3228	Belongs to the MtfA family
LQF05_RS02800	COG4303	Ethanolamine ammonia lyase large subunit
LQF05_RS02805	COG0531	amino acid
LQF05_RS02815	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LQF05_RS02840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LQF05_RS02840	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LQF05_RS02845	COG0802	atpase or kinase
LQF05_RS02850	COG0860	N-Acetylmuramoyl-L-alanine amidase
LQF05_RS02855	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LQF05_RS02860	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LQF05_RS02865	COG1923	regulation of RNA biosynthetic process
LQF05_RS02870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LQF05_RS02875	COG0330	HflC and HflK could
LQF05_RS02880	COG0330	HflC and HflK could
LQF05_RS02885	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LQF05_RS02890	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LQF05_RS02905	COG0557	exoribonuclease II activity
LQF05_RS02910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LQF05_RS02915	COG4191	Histidine kinase
LQF05_RS02915	COG0784	Response regulator, receiver
LQF05_RS02920	COG0360	Binds together with S18 to 16S ribosomal RNA
LQF05_RS02925	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LQF05_RS02935	COG0359	binds to the 23S rRNA
LQF05_RS02940	COG0305	Participates in initiation and elongation during chromosome replication
LQF05_RS02945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LQF05_RS02950	COG5001	Diguanylate cyclase
LQF05_RS02950	COG3300	MHYT domain
LQF05_RS03025	COG1252	NADH dehydrogenase
LQF05_RS03050	COG2945	thiolester hydrolase activity
LQF05_RS03055	COG0180	Tryptophanyl-tRNA synthetase
LQF05_RS03060	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LQF05_RS03070	COG1515	deoxyribonuclease V activity
LQF05_RS03075	COG3023	N-Acetylmuramoyl-L-alanine amidase
LQF05_RS03085	COG0840	transmembrane signaling receptor activity
LQF05_RS03090	COG0084	hydrolase, TatD family'
LQF05_RS03100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LQF05_RS03100	COG2169	Transcriptional regulator
LQF05_RS03115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF05_RS03130	COG0840	transmembrane signaling receptor activity
LQF05_RS03140	COG2217	Heavy metal translocating P-type atpase
LQF05_RS03150	COG1309	transcriptional regulator
LQF05_RS03155	COG2814	Major facilitator Superfamily
LQF05_RS03165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LQF05_RS03195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LQF05_RS03200	COG0778	Nitroreductase
LQF05_RS03205	COG0596	Alpha beta hydrolase
LQF05_RS03210	COG0251	oxidation-reduction process
LQF05_RS03215	COG1335	isochorismatase
LQF05_RS03220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LQF05_RS03225	COG1309	transcriptional regulator
LQF05_RS03245	COG4977	sequence-specific DNA binding
LQF05_RS03255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LQF05_RS03265	COG0346	lactoylglutathione lyase activity
LQF05_RS03300	COG3845	ABC transporter
LQF05_RS03310	COG1079	Belongs to the binding-protein-dependent transport system permease family
LQF05_RS03330	COG1278	Cold shock
LQF05_RS03335	COG2824	Alkylphosphonate utilization operon protein PhnA
LQF05_RS03340	COG1607	acyl-coa hydrolase
LQF05_RS03350	COG0402	S-adenosylhomocysteine deaminase activity
LQF05_RS03355	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LQF05_RS03370	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
LQF05_RS03385	COG2154	pterin-4-alpha-carbinolamine dehydratase
LQF05_RS03405	COG1760	l-serine dehydratase
LQF05_RS03410	COG0492	ferredoxin-NADP+ reductase activity
LQF05_RS03425	COG3189	MarR family transcriptional regulator
LQF05_RS03440	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS03445	COG0348	domain, Protein
LQF05_RS03445	COG3901	Regulator of nitric oxide reductase transcription
LQF05_RS03450	COG4263	nitrous-oxide reductase activity
LQF05_RS03465	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LQF05_RS03485	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS03490	COG0840	transmembrane signaling receptor activity
LQF05_RS03515	COG1648	precorrin-2 dehydrogenase activity
LQF05_RS03515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LQF05_RS03520	COG0535	radical SAM domain protein
LQF05_RS03530	COG1845	cytochrome c oxidase, subunit III
LQF05_RS03535	COG0714	Associated with various cellular activities
LQF05_RS03550	COG2010	Cytochrome c
LQF05_RS03555	COG3391	amine dehydrogenase activity
LQF05_RS03580	COG2010	Cytochrome c
LQF05_RS03585	COG3256	nitric oxide reductase
LQF05_RS03615	COG3604	Transcriptional regulator
LQF05_RS03625	COG0826	peptidase U32
LQF05_RS03630	COG0826	peptidase U32
LQF05_RS03635	COG3154	lipid carrier protein
LQF05_RS03685	COG2814	Major facilitator Superfamily
LQF05_RS03705	COG1737	Transcriptional regulator
LQF05_RS03720	COG0800	Aldolase
LQF05_RS03730	COG4989	oxidoreductase activity
LQF05_RS03745	COG4580	involved in the transport of maltose and maltodextrins
LQF05_RS03760	COG0366	Alpha amylase catalytic
LQF05_RS03770	COG1175	transmembrane transport
LQF05_RS03775	COG3833	ABC-type maltose transport systems, permease component
LQF05_RS03780	COG2909	trisaccharide binding
LQF05_RS03800	COG0366	Alpha amylase catalytic
LQF05_RS03815	COG1280	lysine exporter protein (LysE YggA)
LQF05_RS03845	COG3012	SEC-C Motif Domain Protein
LQF05_RS03860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LQF05_RS03875	COG0514	ATP-dependent DNA helicase (RecQ)
LQF05_RS03900	COG2003	Belongs to the UPF0758 family
LQF05_RS03940	COG0582	viral genome integration into host DNA
LQF05_RS03965	COG1139	Iron-sulfur cluster binding protein
LQF05_RS03970	COG0247	lactate metabolic process
LQF05_RS03975	COG1620	l-lactate permease
LQF05_RS03985	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LQF05_RS03995	COG2914	Belongs to the UPF0125 (RnfH) family
LQF05_RS04000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LQF05_RS04010	COG0497	DNA recombination
LQF05_RS04015	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LQF05_RS04020	COG0443	Heat shock 70 kDa protein
LQF05_RS04025	COG0484	heat shock protein binding
LQF05_RS04030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LQF05_RS04035	COG0505	Belongs to the CarA family
LQF05_RS04065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LQF05_RS04070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LQF05_RS04075	COG0149	triose-phosphate isomerase activity
LQF05_RS04080	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LQF05_RS04095	COG0779	Required for maturation of 30S ribosomal subunits
LQF05_RS04100	COG2251	uridine kinase activity
LQF05_RS04100	COG0195	Participates in both transcription termination and antitermination
LQF05_RS04105	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LQF05_RS04110	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LQF05_RS04115	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LQF05_RS04120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LQF05_RS04125	COG1185	polyribonucleotide nucleotidyltransferase activity
LQF05_RS04150	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LQF05_RS04160	COG0166	Belongs to the GPI family
LQF05_RS04165	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LQF05_RS04170	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LQF05_RS04175	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LQF05_RS04195	COG4191	Histidine kinase
LQF05_RS04205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LQF05_RS04210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LQF05_RS04215	COG0436	Aminotransferase
LQF05_RS04230	COG0679	Auxin Efflux Carrier
LQF05_RS04245	COG2124	cytochrome p450
LQF05_RS04250	COG0784	Response regulator, receiver
LQF05_RS04250	COG2205	protein histidine kinase activity
LQF05_RS04250	COG5002	protein histidine kinase activity
LQF05_RS04260	COG0138	bifunctional purine biosynthesis protein purh
LQF05_RS04280	COG2264	protein methyltransferase activity
LQF05_RS04295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LQF05_RS04310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LQF05_RS04345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LQF05_RS04365	COG0028	Belongs to the TPP enzyme family
LQF05_RS04375	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LQF05_RS04380	COG1183	phosphatidylcholine synthase activity
LQF05_RS04390	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LQF05_RS04420	COG2995	paraquat-inducible protein a
LQF05_RS04425	COG2995	paraquat-inducible protein a
LQF05_RS04430	COG3008	intermembrane lipid transfer
LQF05_RS04450	COG0019	diaminopimelate decarboxylase activity
LQF05_RS04460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LQF05_RS04470	COG0456	acetyltransferase
LQF05_RS04490	COG0288	reversible hydration of carbon dioxide
LQF05_RS04495	COG0697	spore germination
LQF05_RS04525	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LQF05_RS04540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LQF05_RS04550	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LQF05_RS04555	COG0789	Transcriptional regulator
LQF05_RS04585	COG1024	Enoyl-CoA hydratase
LQF05_RS04590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LQF05_RS04595	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS04600	COG4294	response to UV
LQF05_RS04605	COG0318	PFAM AMP-dependent synthetase and ligase
LQF05_RS04635	COG0559	Belongs to the binding-protein-dependent transport system permease family
LQF05_RS04660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LQF05_RS04680	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LQF05_RS04685	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LQF05_RS04695	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LQF05_RS04700	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LQF05_RS04710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LQF05_RS04715	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LQF05_RS04735	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LQF05_RS04740	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LQF05_RS04780	COG0653	protein targeting
LQF05_RS04785	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LQF05_RS04825	COG2096	Adenosyltransferase
LQF05_RS04830	COG4191	Histidine kinase
LQF05_RS04840	COG0745	RESPONSE REGULATOR receiver
LQF05_RS04845	COG1666	GTP binding
LQF05_RS04850	COG0668	transmembrane transport
LQF05_RS04870	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS04880	COG3030	protein affecting phage T7 exclusion by the F plasmid
LQF05_RS04885	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LQF05_RS04890	COG0459	protein refolding
LQF05_RS04900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF05_RS04905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQF05_RS04935	COG1704	LemA family
LQF05_RS04960	COG1279	arginine transmembrane transporter activity
LQF05_RS04965	COG0583	DNA-binding transcription factor activity
LQF05_RS04985	COG3706	GGDEF domain
LQF05_RS04990	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LQF05_RS05005	COG1017	nitric oxide dioxygenase activity
LQF05_RS05005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LQF05_RS05015	COG4413	Urea transporter
LQF05_RS05020	COG0469	pyruvate kinase activity
LQF05_RS05030	COG2084	Dehydrogenase
LQF05_RS05035	COG3622	Belongs to the hyi family
LQF05_RS05040	COG3960	tartronate-semialdehyde synthase activity
LQF05_RS05045	COG0583	DNA-binding transcription factor activity
LQF05_RS05050	COG2351	hydroxyisourate hydrolase activity
LQF05_RS05070	COG0708	Exodeoxyribonuclease III
LQF05_RS05075	COG3300	MHYT domain
LQF05_RS05075	COG5001	Diguanylate cyclase
LQF05_RS05100	COG1309	transcriptional regulator
LQF05_RS05105	COG0840	transmembrane signaling receptor activity
LQF05_RS05115	COG2233	PERMEase
LQF05_RS05120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LQF05_RS05120	COG4651	solute:proton antiporter activity
LQF05_RS05125	COG2233	PERMEase
LQF05_RS05135	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LQF05_RS05140	COG4266	Belongs to the allantoicase family
LQF05_RS05165	COG2252	PERMEase
LQF05_RS05170	COG2186	Transcriptional regulator
LQF05_RS05175	COG1121	(ABC) transporter
LQF05_RS05185	COG0803	Belongs to the bacterial solute-binding protein 9 family
LQF05_RS05190	COG0402	S-adenosylhomocysteine deaminase activity
LQF05_RS05230	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LQF05_RS05235	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LQF05_RS05255	COG2326	polyphosphate kinase activity
LQF05_RS05260	COG3081	Nucleoid-associated protein
LQF05_RS05285	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LQF05_RS05290	COG0477	Major facilitator Superfamily
LQF05_RS05295	COG0471	metal ion transport
LQF05_RS05295	COG0490	domain, Protein
LQF05_RS05325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LQF05_RS05330	COG0795	lipopolysaccharide-transporting ATPase activity
LQF05_RS05335	COG0795	lipopolysaccharide-transporting ATPase activity
LQF05_RS05345	COG1278	Cold shock
LQF05_RS05365	COG1862	Preprotein translocase
LQF05_RS05380	COG3134	Outer membrane lipoprotein
LQF05_RS05405	COG1104	cysteine desulfurase activity
LQF05_RS05415	COG0316	Belongs to the HesB IscA family
LQF05_RS05420	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LQF05_RS05425	COG0443	Heat shock 70 kDa protein
LQF05_RS05440	COG0105	UTP biosynthetic process
LQF05_RS05445	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LQF05_RS05460	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LQF05_RS05465	COG0124	histidyl-tRNA synthetase
LQF05_RS05470	COG2976	Protein conserved in bacteria
LQF05_RS05480	COG1160	GTP binding
LQF05_RS05485	COG1045	serine acetyltransferase
LQF05_RS05490	COG0436	Aminotransferase
LQF05_RS05505	COG2264	protein methyltransferase activity
LQF05_RS05515	COG3647	Membrane
LQF05_RS05520	COG2356	endonuclease I
LQF05_RS05530	COG1064	alcohol dehydrogenase
LQF05_RS05540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LQF05_RS05555	COG0668	transmembrane transport
LQF05_RS05565	COG0739	heme binding
LQF05_RS05570	COG1570	exodeoxyribonuclease VII activity
LQF05_RS05585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LQF05_RS05585	COG0519	Catalyzes the synthesis of GMP from XMP
LQF05_RS05590	COG2132	Multicopper oxidase
LQF05_RS05595	COG0590	tRNA wobble adenosine to inosine editing
LQF05_RS05600	COG3842	ATPase activity
LQF05_RS05610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LQF05_RS05630	COG0556	nucleotide-excision repair
LQF05_RS05635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LQF05_RS05670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LQF05_RS05700	COG3267	Type II secretory pathway component ExeA
LQF05_RS05700	COG3409	Peptidoglycan-binding domain 1 protein
LQF05_RS05710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LQF05_RS05715	COG1459	type II secretion system
LQF05_RS05720	COG2165	general secretion pathway protein
LQF05_RS05800	COG3639	organic phosphonate transmembrane transporter activity
LQF05_RS05805	COG3639	organic phosphonate transmembrane transporter activity
LQF05_RS05815	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LQF05_RS05825	COG1968	undecaprenyl-diphosphatase activity
LQF05_RS05830	COG2084	Dehydrogenase
LQF05_RS05835	COG3622	Belongs to the hyi family
LQF05_RS05840	COG2271	Major facilitator Superfamily
LQF05_RS05845	COG0443	Heat shock 70 kDa protein
LQF05_RS05855	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LQF05_RS05880	COG2030	dehydratase
LQF05_RS05885	COG0318	PFAM AMP-dependent synthetase and ligase
LQF05_RS05910	COG1643	Atp-dependent helicase
LQF05_RS05925	COG0515	serine threonine protein kinase
LQF05_RS05925	COG2815	serine threonine protein kinase
LQF05_RS05930	COG0631	protein serine/threonine phosphatase activity
LQF05_RS05935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LQF05_RS05940	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
LQF05_RS05945	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LQF05_RS05950	COG3257	ureidoglycine aminohydrolase activity
LQF05_RS05965	COG1234	tRNA 3'-trailer cleavage
LQF05_RS05975	COG2851	Citrate transporter
LQF05_RS05990	COG3795	YCII-related domain
LQF05_RS06005	COG2258	MOSC domain
LQF05_RS06015	COG0537	adenosine 5'-monophosphoramidase activity
LQF05_RS06035	COG2733	membrane
LQF05_RS06060	COG1279	arginine transmembrane transporter activity
LQF05_RS06085	COG0508	dehydrogenase complex catalyzes the overall conversion of
LQF05_RS06085	COG0596	Alpha beta hydrolase
LQF05_RS06095	COG2814	Major facilitator Superfamily
LQF05_RS06105	COG0471	metal ion transport
LQF05_RS06105	COG0490	domain, Protein
LQF05_RS06115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LQF05_RS06120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LQF05_RS06130	COG1301	dicarboxylic acid transport
LQF05_RS06145	COG1079	Belongs to the binding-protein-dependent transport system permease family
LQF05_RS06150	COG4603	Belongs to the binding-protein-dependent transport system permease family
LQF05_RS06155	COG3845	ABC transporter
LQF05_RS06160	COG2207	Transcriptional regulator
LQF05_RS06170	COG4221	oxidoreductase activity
LQF05_RS06180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LQF05_RS06190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LQF05_RS06205	COG0159	tryptophan synthase activity
LQF05_RS06245	COG1132	(ABC) transporter
LQF05_RS06250	COG4249	Peptidase C14 caspase catalytic subunit p20
LQF05_RS06260	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LQF05_RS06280	COG1280	lysine exporter protein (LysE YggA)
LQF05_RS06305	COG0625	glutathione transferase activity
LQF05_RS06310	COG0583	DNA-binding transcription factor activity
LQF05_RS06340	COG0508	dehydrogenase complex catalyzes the overall conversion of
LQF05_RS06345	COG0508	dehydrogenase complex catalyzes the overall conversion of
LQF05_RS06350	COG0022	dehydrogenase e1 component
LQF05_RS06355	COG1063	alcohol dehydrogenase
LQF05_RS06360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LQF05_RS06375	COG3284	Transcriptional regulator
LQF05_RS06385	COG0604	alcohol dehydrogenase
LQF05_RS06385	COG3321	synthase
LQF05_RS06400	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LQF05_RS06405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LQF05_RS06405	COG0116	Belongs to the methyltransferase superfamily
LQF05_RS06410	COG0189	ligase activity
LQF05_RS06410	COG4067	protein conserved in archaea
LQF05_RS06415	COG0583	DNA-binding transcription factor activity
LQF05_RS06420	COG1309	transcriptional regulator
LQF05_RS06440	COG1462	curli production assembly transport component CsgG
LQF05_RS06460	COG1280	lysine exporter protein (LysE YggA)
LQF05_RS06470	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS06475	COG0583	DNA-binding transcription factor activity
LQF05_RS06480	COG3932	Exopolysaccharide synthesis, ExoD
LQF05_RS06485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LQF05_RS06495	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LQF05_RS06505	COG3530	Putative quorum-sensing-regulated virulence factor
LQF05_RS06515	COG2863	cytochrome
LQF05_RS06520	COG3258	Cytochrome c
LQF05_RS06530	COG2166	iron-sulfur cluster assembly
LQF05_RS06535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LQF05_RS06540	COG2171	N-acyltransferase activity
LQF05_RS06545	COG1393	Belongs to the ArsC family
LQF05_RS06565	COG0436	Aminotransferase
LQF05_RS06580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LQF05_RS06585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LQF05_RS06595	COG0628	permease
LQF05_RS06600	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LQF05_RS06620	COG1295	ribonuclease BN
LQF05_RS06635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LQF05_RS06650	COG0442	prolyl-tRNA aminoacylation
LQF05_RS06665	COG2900	Belongs to the SlyX family
LQF05_RS06675	COG0783	Belongs to the Dps family
LQF05_RS06680	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LQF05_RS06690	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LQF05_RS06695	COG0632	four-way junction helicase activity
LQF05_RS06700	COG2255	four-way junction helicase activity
LQF05_RS06705	COG0824	Thioesterase
LQF05_RS06725	COG0823	Involved in the tonB-independent uptake of proteins
LQF05_RS06730	COG2885	chlorophyll binding
LQF05_RS06735	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LQF05_RS06740	COG0602	queuosine metabolic process
LQF05_RS06745	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LQF05_RS06755	COG0427	acetyl-CoA hydrolase
LQF05_RS06760	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LQF05_RS06770	COG0425	Belongs to the sulfur carrier protein TusA family
LQF05_RS06780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LQF05_RS06790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LQF05_RS06800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LQF05_RS06810	COG0417	DNA replication proofreading
LQF05_RS06845	COG3174	membrane
LQF05_RS06850	COG2205	protein histidine kinase activity
LQF05_RS06870	COG2814	Major facilitator Superfamily
LQF05_RS06875	COG2974	May be involved in recombination
LQF05_RS06890	COG0545	Peptidyl-prolyl cis-trans isomerase
LQF05_RS06915	COG1914	H( )-stimulated, divalent metal cation uptake system
LQF05_RS06920	COG4336	lyase activity
LQF05_RS06925	COG1984	allophanate hydrolase subunit 2
LQF05_RS06930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LQF05_RS06935	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LQF05_RS06945	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LQF05_RS06950	COG3383	formate dehydrogenase (NAD+) activity
LQF05_RS06955	COG1902	pentaerythritol trinitrate reductase activity
LQF05_RS06970	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LQF05_RS07010	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LQF05_RS07015	COG0563	adenylate kinase activity
LQF05_RS07040	COG0742	ribosomal rna small subunit methyltransferase
LQF05_RS07050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQF05_RS07055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF05_RS07060	COG1309	transcriptional regulator
LQF05_RS07080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LQF05_RS07085	COG0348	domain, Protein
LQF05_RS07090	COG1380	Effector of murein hydrolase LrgA
LQF05_RS07095	COG1346	cytolysis
LQF05_RS07105	COG1472	Belongs to the glycosyl hydrolase 3 family
LQF05_RS07115	COG2943	transferase activity, transferring hexosyl groups
LQF05_RS07130	COG0655	NAD(P)H dehydrogenase (quinone) activity
LQF05_RS07135	COG0456	acetyltransferase
LQF05_RS07160	COG2132	Multicopper oxidase
LQF05_RS07185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LQF05_RS07200	COG0456	acetyltransferase
LQF05_RS07205	COG2937	Belongs to the GPAT DAPAT family
LQF05_RS07235	COG0456	acetyltransferase
LQF05_RS07240	COG1131	(ABC) transporter
LQF05_RS07265	COG2226	methyltransferase
LQF05_RS07270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LQF05_RS07275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LQF05_RS07320	COG0513	Belongs to the DEAD box helicase family
LQF05_RS07335	COG0583	DNA-binding transcription factor activity
LQF05_RS07355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LQF05_RS07355	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LQF05_RS07360	COG0784	Response regulator, receiver
LQF05_RS07360	COG2205	protein histidine kinase activity
LQF05_RS07360	COG5002	protein histidine kinase activity
LQF05_RS07365	COG2860	membrane
LQF05_RS07380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LQF05_RS07385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LQF05_RS07390	COG3956	TIGRFAM MazG family protein
LQF05_RS07420	COG1201	RNA secondary structure unwinding
LQF05_RS07425	COG1793	dna ligase
LQF05_RS07440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LQF05_RS07450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LQF05_RS07465	COG1805	sodium ion transport
LQF05_RS07480	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LQF05_RS07490	COG1477	protein flavinylation
LQF05_RS07500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LQF05_RS07505	COG0584	glycerophosphoryl diester phosphodiesterase
LQF05_RS07520	COG4591	ABC-type transport system involved in lipoprotein release permease component
LQF05_RS07525	COG1136	(ABC) transporter
LQF05_RS07540	COG0658	competence protein
LQF05_RS07540	COG2333	competence protein COMEC
LQF05_RS07545	COG0811	peptide transport
LQF05_RS07555	COG1663	tetraacyldisaccharide 4'-kinase activity
LQF05_RS07560	COG2835	tetraacyldisaccharide 4'-kinase activity
LQF05_RS07565	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LQF05_RS07570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LQF05_RS07575	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LQF05_RS07580	COG1530	ribonuclease E activity
LQF05_RS07595	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LQF05_RS07595	COG0616	signal peptide processing
LQF05_RS07600	COG0424	maF-like protein
LQF05_RS07610	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LQF05_RS07615	COG0416	fatty acid biosynthetic process
LQF05_RS07630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LQF05_RS07635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LQF05_RS07645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LQF05_RS07650	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LQF05_RS07665	COG0084	hydrolase, TatD family'
LQF05_RS07670	COG1113	amino acid transport
LQF05_RS07730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LQF05_RS07740	COG5001	Diguanylate cyclase
LQF05_RS07740	COG3300	MHYT domain
LQF05_RS07755	COG2130	NADP-dependent
LQF05_RS07780	COG0583	DNA-binding transcription factor activity
LQF05_RS07805	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LQF05_RS07810	COG2226	methyltransferase
LQF05_RS07820	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LQF05_RS07825	COG0583	DNA-binding transcription factor activity
LQF05_RS07845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LQF05_RS07855	COG0745	RESPONSE REGULATOR receiver
LQF05_RS07860	COG2205	protein histidine kinase activity
LQF05_RS07870	COG0668	transmembrane transport
LQF05_RS07915	COG2988	succinylglutamate desuccinylase activity
LQF05_RS07920	COG1131	(ABC) transporter
LQF05_RS07925	COG0842	Transport permease protein
LQF05_RS07930	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LQF05_RS07930	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LQF05_RS07940	COG2853	Lipoprotein
LQF05_RS07950	COG0745	RESPONSE REGULATOR receiver
LQF05_RS07960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LQF05_RS08005	COG1160	GTP binding
LQF05_RS08030	COG1357	PFAM Pentapeptide repeats (8 copies)
LQF05_RS08035	COG4628	conserved protein (DUF2132)
LQF05_RS08145	COG0582	viral genome integration into host DNA
LQF05_RS08325	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LQF05_RS08345	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LQF05_RS08355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQF05_RS08360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF05_RS08425	COG0469	pyruvate kinase activity
LQF05_RS08440	COG2135	peptidase activity
LQF05_RS08495	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LQF05_RS08500	COG0732	type I restriction modification DNA specificity domain
LQF05_RS08505	COG1401	restriction endodeoxyribonuclease activity
LQF05_RS08505	COG1401	restriction endodeoxyribonuclease activity
LQF05_RS08530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LQF05_RS08535	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LQF05_RS08545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LQF05_RS08580	COG2814	Major facilitator Superfamily
LQF05_RS08585	COG4948	Mandelate Racemase Muconate Lactonizing
LQF05_RS08590	COG4829	muconolactone delta-isomerase
LQF05_RS08595	COG3485	protocatechuate 3,4-dioxygenase
LQF05_RS08600	COG3135	benzoate transporter
LQF05_RS08635	COG0784	Response regulator, receiver
LQF05_RS08635	COG4191	Histidine kinase
LQF05_RS08645	COG0114	fumarate hydratase activity
LQF05_RS08655	COG0271	Belongs to the BolA IbaG family
LQF05_RS08660	COG1054	Belongs to the UPF0176 family
LQF05_RS08675	COG0840	transmembrane signaling receptor activity
LQF05_RS08700	COG0583	DNA-binding transcription factor activity
LQF05_RS08705	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LQF05_RS08710	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS08720	COG2079	MmgE PrpD family protein
LQF05_RS08730	COG2301	Belongs to the HpcH HpaI aldolase family
LQF05_RS08765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LQF05_RS08770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LQF05_RS08775	COG0583	DNA-binding transcription factor activity
LQF05_RS08790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LQF05_RS08800	COG1770	oligopeptidase
LQF05_RS08805	COG1024	Enoyl-CoA hydratase
LQF05_RS08805	COG1250	3-hydroxyacyl-CoA dehydrogenase
LQF05_RS08810	COG0183	Belongs to the thiolase family
LQF05_RS08875	COG0653	protein targeting
LQF05_RS08895	COG0133	tryptophan synthase activity
LQF05_RS08900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LQF05_RS08905	COG1012	belongs to the aldehyde dehydrogenase family
LQF05_RS08910	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LQF05_RS08915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LQF05_RS08940	COG0297	glycogen (starch) synthase activity
LQF05_RS08970	COG0250	Participates in transcription elongation, termination and antitermination
LQF05_RS09030	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS09045	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LQF05_RS09050	COG0066	3-isopropylmalate dehydratase activity
LQF05_RS09080	COG0135	phosphoribosylanthranilate isomerase activity
LQF05_RS09085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LQF05_RS09090	COG0285	dihydrofolate synthase activity
LQF05_RS09100	COG1286	toxin biosynthetic process
LQF05_RS09135	COG0789	Transcriptional regulator
LQF05_RS09165	COG4771	TonB-dependent receptor
LQF05_RS09170	COG0254	rRNA binding
LQF05_RS09185	COG0655	NAD(P)H dehydrogenase (quinone) activity
LQF05_RS09190	COG2814	Major facilitator Superfamily
LQF05_RS09215	COG1271	oxidase subunit
LQF05_RS09220	COG1294	oxidase, subunit
LQF05_RS09240	COG0446	pyridine nucleotide-disulphide oxidoreductase
LQF05_RS09240	COG1902	pentaerythritol trinitrate reductase activity
LQF05_RS09270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LQF05_RS09275	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LQF05_RS09280	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LQF05_RS09285	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LQF05_RS09300	COG0573	inorganic phosphate transmembrane transporter activity
LQF05_RS09315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LQF05_RS09320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LQF05_RS09330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LQF05_RS09360	COG2010	Cytochrome c
LQF05_RS09375	COG3278	Belongs to the heme-copper respiratory oxidase family
LQF05_RS09380	COG2010	Cytochrome c
LQF05_RS09390	COG3278	Belongs to the heme-copper respiratory oxidase family
LQF05_RS09400	COG0840	transmembrane signaling receptor activity
LQF05_RS09410	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LQF05_RS09430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LQF05_RS09435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LQF05_RS09435	COG2010	Cytochrome c
LQF05_RS09450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LQF05_RS09455	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LQF05_RS09465	COG3115	cell septum assembly
LQF05_RS09470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LQF05_RS09500	COG3123	guanosine phosphorylase activity
LQF05_RS09520	COG2009	succinate dehydrogenase
LQF05_RS09525	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LQF05_RS09530	COG1053	succinate dehydrogenase
LQF05_RS09535	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LQF05_RS09555	COG0045	succinate-CoA ligase (ADP-forming) activity
LQF05_RS09590	COG0326	Molecular chaperone. Has ATPase activity
LQF05_RS09620	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LQF05_RS09630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LQF05_RS09635	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LQF05_RS09670	COG0628	permease
LQF05_RS09680	COG0709	Synthesizes selenophosphate from selenide and ATP
LQF05_RS09685	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
LQF05_RS09695	COG0714	Associated with various cellular activities
LQF05_RS09720	COG1238	metal cluster binding
LQF05_RS09735	COG0183	Belongs to the thiolase family
LQF05_RS09740	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS09745	COG0318	PFAM AMP-dependent synthetase and ligase
LQF05_RS09750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LQF05_RS09760	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS09765	COG1024	Enoyl-CoA hydratase
LQF05_RS09800	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LQF05_RS09815	COG2205	protein histidine kinase activity
LQF05_RS09820	COG0745	RESPONSE REGULATOR receiver
LQF05_RS09825	COG0058	SHG alpha-glucan phosphorylase activity
LQF05_RS09840	COG2207	Transcriptional regulator
LQF05_RS09855	COG4991	sh3 domain protein
LQF05_RS09860	COG4191	Histidine kinase
LQF05_RS09860	COG0784	Response regulator, receiver
LQF05_RS09865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LQF05_RS09885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LQF05_RS09900	COG5001	Diguanylate cyclase
LQF05_RS09900	COG5002	protein histidine kinase activity
LQF05_RS09900	COG3447	MASE1 domain protein
LQF05_RS09940	COG0210	DNA helicase
LQF05_RS09945	COG0515	serine threonine protein kinase
LQF05_RS09955	COG2146	nitrite reductase [NAD(P)H] activity
LQF05_RS09955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LQF05_RS09960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LQF05_RS09960	COG2146	nitrite reductase [NAD(P)H] activity
LQF05_RS09975	COG0840	transmembrane signaling receptor activity
LQF05_RS09980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LQF05_RS09995	COG4221	oxidoreductase activity
LQF05_RS10005	COG0415	Belongs to the DNA photolyase family
LQF05_RS10010	COG0789	Transcriptional regulator
LQF05_RS10015	COG3272	Protein of unknown function (DUF1722)
LQF05_RS10020	COG1090	epimerase
LQF05_RS10025	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LQF05_RS10035	COG1366	Belongs to the anti-sigma-factor antagonist family
LQF05_RS10055	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LQF05_RS10060	COG0302	gtp cyclohydrolase
LQF05_RS10070	COG0789	Transcriptional regulator
LQF05_RS10075	COG1025	Belongs to the peptidase M16 family
LQF05_RS10090	COG0784	Response regulator, receiver
LQF05_RS10090	COG2205	protein histidine kinase activity
LQF05_RS10095	COG0435	Glutathione S-transferase
LQF05_RS10100	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LQF05_RS10105	COG2920	part of a sulfur-relay system
LQF05_RS10155	COG0174	glutamine synthetase
LQF05_RS10160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LQF05_RS10165	COG1116	anion transmembrane transporter activity
LQF05_RS10170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LQF05_RS10180	COG1335	isochorismatase
LQF05_RS10200	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS10210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LQF05_RS10225	COG4770	biotin carboxylase activity
LQF05_RS10235	COG3665	Urea carboxylase-associated protein
LQF05_RS10240	COG3842	ATPase activity
LQF05_RS10255	COG0084	hydrolase, TatD family'
LQF05_RS10260	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LQF05_RS10280	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LQF05_RS10285	COG4181	ATPase activity
LQF05_RS10315	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LQF05_RS10320	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LQF05_RS10335	COG0560	Phosphoserine phosphatase
LQF05_RS10360	COG1802	Transcriptional regulator
LQF05_RS10370	COG0372	Belongs to the citrate synthase family
LQF05_RS10385	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LQF05_RS10395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LQF05_RS10410	COG0668	transmembrane transport
LQF05_RS10445	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LQF05_RS10450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LQF05_RS10455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LQF05_RS10460	COG0215	cysteine-tRNA ligase activity
LQF05_RS10465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LQF05_RS10485	COG2186	Transcriptional regulator
LQF05_RS10495	COG0544	peptidyl-prolyl cis-trans isomerase activity
LQF05_RS10505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LQF05_RS10510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LQF05_RS10520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LQF05_RS10525	COG0167	dihydroorotate dehydrogenase activity
LQF05_RS10530	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LQF05_RS10570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LQF05_RS10575	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
LQF05_RS10585	COG0535	radical SAM domain protein
LQF05_RS10600	COG5002	protein histidine kinase activity
LQF05_RS10615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LQF05_RS10620	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF05_RS10675	COG0798	PFAM Bile acid sodium symporter
LQF05_RS10680	COG2072	flavoprotein involved in K transport
LQF05_RS10685	COG0640	Transcriptional regulator
LQF05_RS10690	COG0431	NADPH-dependent FMN reductase
LQF05_RS10700	COG1742	UPF0060 membrane protein
LQF05_RS10705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LQF05_RS10730	COG5642	Protein of unknown function (DUF2384)
LQF05_RS10780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LQF05_RS10815	COG1061	Type III restriction enzyme res subunit
LQF05_RS10935	COG1566	PFAM secretion protein HlyD family protein
LQF05_RS10945	COG0583	DNA-binding transcription factor activity
LQF05_RS10960	COG0723	plastoquinol--plastocyanin reductase activity
LQF05_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS10970	COG0028	Belongs to the TPP enzyme family
LQF05_RS10995	COG3685	Protein conserved in bacteria
LQF05_RS11000	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LQF05_RS11000	COG3264	Mechanosensitive ion channel
LQF05_RS11005	COG1058	Belongs to the CinA family
LQF05_RS11005	COG1546	Belongs to the CinA family
LQF05_RS11010	COG0297	glycogen (starch) synthase activity
LQF05_RS11015	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LQF05_RS11040	COG0739	heme binding
LQF05_RS11050	COG3384	dioxygenase
LQF05_RS11055	COG0583	DNA-binding transcription factor activity
LQF05_RS11070	COG3568	Endonuclease Exonuclease Phosphatase
LQF05_RS11075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LQF05_RS11080	COG0392	lysyltransferase activity
LQF05_RS11085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LQF05_RS11090	COG0366	Alpha amylase catalytic
LQF05_RS11110	COG2864	formate dehydrogenase
LQF05_RS11115	COG0437	4 iron, 4 sulfur cluster binding
LQF05_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS11140	COG3321	synthase
LQF05_RS11140	COG0604	alcohol dehydrogenase
LQF05_RS11190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LQF05_RS11200	COG0728	peptidoglycan biosynthetic process
LQF05_RS11215	COG1115	amino acid carrier protein
LQF05_RS11220	COG2911	Protein conserved in bacteria
LQF05_RS11225	COG0729	surface antigen
LQF05_RS11245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LQF05_RS11260	COG1175	transmembrane transport
LQF05_RS11280	COG1070	Carbohydrate kinase
LQF05_RS11295	COG1609	Transcriptional regulator
LQF05_RS11300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LQF05_RS11305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LQF05_RS11310	COG3265	gluconokinase activity
LQF05_RS11315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LQF05_RS11320	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LQF05_RS11345	COG0488	(ABC) transporter
LQF05_RS11350	COG1968	undecaprenyl-diphosphatase activity
LQF05_RS11355	COG0840	transmembrane signaling receptor activity
LQF05_RS11370	COG2323	membrane
LQF05_RS11385	COG3706	GGDEF domain
LQF05_RS11390	COG2201	protein-glutamate methylesterase activity
LQF05_RS11395	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LQF05_RS11395	COG0316	Belongs to the HesB IscA family
LQF05_RS11415	COG2755	lipolytic protein G-D-S-L family
LQF05_RS11415	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LQF05_RS11440	COG2223	nitrite transmembrane transporter activity
LQF05_RS11445	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LQF05_RS11460	COG0071	Belongs to the small heat shock protein (HSP20) family
LQF05_RS11480	COG0604	alcohol dehydrogenase
LQF05_RS11485	COG0616	signal peptide processing
LQF05_RS11505	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS11520	COG2816	NAD+ diphosphatase activity
LQF05_RS11530	COG1024	Enoyl-CoA hydratase
LQF05_RS11540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LQF05_RS11545	COG0328	RNA-DNA hybrid ribonuclease activity
LQF05_RS11555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LQF05_RS11560	COG0741	lytic transglycosylase activity
LQF05_RS11560	COG1388	LysM domain
LQF05_RS11570	COG4166	transmembrane transport
LQF05_RS11580	COG4174	ABC transporter (Permease)
LQF05_RS11585	COG4239	(ABC) transporter, permease
LQF05_RS11590	COG4172	Belongs to the ABC transporter superfamily
LQF05_RS11620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LQF05_RS11680	COG0840	transmembrane signaling receptor activity
LQF05_RS11700	COG1131	(ABC) transporter
LQF05_RS11720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LQF05_RS11720	COG1648	precorrin-2 dehydrogenase activity
LQF05_RS11725	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LQF05_RS11730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LQF05_RS11735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LQF05_RS11740	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LQF05_RS11750	COG0492	ferredoxin-NADP+ reductase activity
LQF05_RS11755	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LQF05_RS11760	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LQF05_RS11765	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LQF05_RS11770	COG0542	response to heat
LQF05_RS11775	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LQF05_RS11780	COG1278	Cold shock
LQF05_RS11800	COG0482	sulfurtransferase activity
LQF05_RS11805	COG2915	High frequency lysogenization protein hflD homolog
LQF05_RS11815	COG2850	peptidyl-arginine hydroxylation
LQF05_RS11820	COG2153	protein acetylation
LQF05_RS11845	COG0628	permease
LQF05_RS11850	COG2056	Na+-H+ antiporter family
LQF05_RS11855	COG0720	synthase
LQF05_RS11885	COG0402	S-adenosylhomocysteine deaminase activity
LQF05_RS11890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LQF05_RS11895	COG0546	phosphoglycolate phosphatase activity
LQF05_RS11900	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS11910	COG0800	Aldolase
LQF05_RS11935	COG2840	Smr protein MutS2
LQF05_RS11945	COG0625	glutathione transferase activity
LQF05_RS11950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LQF05_RS11965	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LQF05_RS11970	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LQF05_RS11980	COG0077	Prephenate dehydratase
LQF05_RS11980	COG1605	Chorismate mutase
LQF05_RS11985	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LQF05_RS11995	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LQF05_RS12010	COG0587	DNA-directed DNA polymerase activity
LQF05_RS12030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LQF05_RS12035	COG0765	amino acid transport
LQF05_RS12040	COG1126	abc transporter atp-binding protein
LQF05_RS12045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LQF05_RS12050	COG0475	glutathione-regulated potassium exporter activity
LQF05_RS12050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LQF05_RS12075	COG0745	RESPONSE REGULATOR receiver
LQF05_RS12090	COG0776	regulation of translation
LQF05_RS12095	COG0072	phenylalanine-tRNA ligase activity
LQF05_RS12100	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LQF05_RS12105	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LQF05_RS12110	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LQF05_RS12120	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LQF05_RS12130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LQF05_RS12205	COG3171	Protein conserved in bacteria
LQF05_RS12210	COG2027	D-alanyl-D-alanine carboxypeptidase
LQF05_RS12215	COG0116	Belongs to the methyltransferase superfamily
LQF05_RS12215	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LQF05_RS12220	COG3130	regulation of translation
LQF05_RS12225	COG0167	dihydroorotate dehydrogenase activity
LQF05_RS12245	COG0714	Associated with various cellular activities
LQF05_RS12275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LQF05_RS12280	COG3707	response regulator
LQF05_RS12300	COG2223	nitrite transmembrane transporter activity
LQF05_RS12305	COG2815	serine threonine protein kinase
LQF05_RS12305	COG0515	serine threonine protein kinase
LQF05_RS12315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LQF05_RS12320	COG2146	nitrite reductase [NAD(P)H] activity
LQF05_RS12325	COG0243	molybdopterin cofactor binding
LQF05_RS12345	COG0308	aminopeptidase N
LQF05_RS12365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LQF05_RS12370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LQF05_RS12385	COG0730	response to heat
LQF05_RS12400	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LQF05_RS12425	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LQF05_RS12440	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LQF05_RS12455	COG4580	involved in the transport of maltose and maltodextrins
LQF05_RS12460	COG3842	ATPase activity
LQF05_RS12465	COG0395	ABC-type sugar transport system, permease component
LQF05_RS12470	COG1175	transmembrane transport
LQF05_RS12475	COG1653	transport
LQF05_RS12500	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LQF05_RS12510	COG0180	Tryptophanyl-tRNA synthetase
LQF05_RS12515	COG0009	L-threonylcarbamoyladenylate synthase
LQF05_RS12520	COG0613	PHP domain protein
LQF05_RS12525	COG2350	Protein conserved in bacteria
LQF05_RS12535	COG0745	RESPONSE REGULATOR receiver
LQF05_RS12550	COG0778	Nitroreductase
LQF05_RS12555	COG0727	PFAM Uncharacterised protein family (UPF0153)
LQF05_RS12560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LQF05_RS12565	COG2354	Protein conserved in bacteria
LQF05_RS12585	COG2207	Transcriptional regulator
LQF05_RS12600	COG1752	Esterase of the alpha-beta hydrolase superfamily
LQF05_RS12610	COG0514	ATP-dependent DNA helicase (RecQ)
LQF05_RS12620	COG2832	Protein of unknown function (DUF454)
LQF05_RS12640	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
LQF05_RS12650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LQF05_RS12660	COG0542	response to heat
LQF05_RS12680	COG0121	glutamine amidotransferase
LQF05_RS12690	COG0589	response to stress
LQF05_RS12700	COG0488	(ABC) transporter
LQF05_RS12705	COG0741	lytic transglycosylase activity
LQF05_RS12710	COG0633	Ferredoxin
LQF05_RS12710	COG3217	Mosc domain protein beta barrel domain protein
LQF05_RS12715	COG3437	response regulator, receiver
LQF05_RS12725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LQF05_RS12730	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LQF05_RS12735	COG0489	protein tyrosine kinase activity
LQF05_RS12735	COG3206	protein involved in exopolysaccharide biosynthesis
LQF05_RS12740	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LQF05_RS12780	COG0183	Belongs to the thiolase family
LQF05_RS12790	COG2977	Belongs to the P-Pant transferase superfamily
LQF05_RS12805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LQF05_RS12815	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LQF05_RS12880	COG0776	regulation of translation
LQF05_RS12890	COG0840	transmembrane signaling receptor activity
LQF05_RS12895	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LQF05_RS12900	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LQF05_RS12905	COG0471	metal ion transport
LQF05_RS12910	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LQF05_RS12965	COG0328	RNA-DNA hybrid ribonuclease activity
LQF05_RS12970	COG4974	Belongs to the 'phage' integrase family
LQF05_RS12980	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
LQF05_RS13005	COG4591	ABC-type transport system involved in lipoprotein release permease component
LQF05_RS13010	COG1136	(ABC) transporter
LQF05_RS13020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LQF05_RS13020	COG3453	Protein conserved in bacteria
LQF05_RS13050	COG0640	Transcriptional regulator
LQF05_RS13085	COG0386	Belongs to the glutathione peroxidase family
LQF05_RS13090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LQF05_RS13095	COG0436	Aminotransferase
LQF05_RS13105	COG0501	Belongs to the peptidase M48B family
LQF05_RS13115	COG0500	methyltransferase
LQF05_RS13165	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LQF05_RS13195	COG2257	FlhB HrpN YscU SpaS Family
LQF05_RS13210	COG0835	chemotaxis
LQF05_RS13220	COG1192	Involved in chromosome partitioning
LQF05_RS13225	COG1360	Flagellar Motor Protein
LQF05_RS13230	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LQF05_RS13235	COG2201	protein-glutamate methylesterase activity
LQF05_RS13240	COG2198	Histidine kinase
LQF05_RS13240	COG0643	Histidine kinase
LQF05_RS13240	COG0784	Response regulator, receiver
LQF05_RS13245	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LQF05_RS13275	COG2032	superoxide dismutase activity
LQF05_RS13290	COG1987	bacterial-type flagellum assembly
LQF05_RS13330	COG0745	RESPONSE REGULATOR receiver
LQF05_RS13365	COG1677	Flagellar hook-basal body complex protein FliE
LQF05_RS13370	COG3135	benzoate transporter
LQF05_RS13385	COG0789	Transcriptional regulator
LQF05_RS13415	COG0826	peptidase U32
LQF05_RS13420	COG0840	transmembrane signaling receptor activity
LQF05_RS13435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LQF05_RS13455	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LQF05_RS13470	COG1283	sodium-dependent phosphate transmembrane transporter activity
LQF05_RS13480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LQF05_RS13485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LQF05_RS13555	COG2258	MOSC domain
LQF05_RS13570	COG0217	transcriptional regulatory protein
LQF05_RS13580	COG0589	response to stress
LQF05_RS13635	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LQF05_RS13640	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LQF05_RS13645	COG0585	pseudouridine synthase activity
LQF05_RS13650	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LQF05_RS13660	COG1902	pentaerythritol trinitrate reductase activity
LQF05_RS13665	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LQF05_RS13675	COG0583	DNA-binding transcription factor activity
LQF05_RS13690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LQF05_RS13705	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LQF05_RS13710	COG0504	CTP synthase activity
LQF05_RS13715	COG0037	tRNA processing
LQF05_RS13720	COG0825	malonyl-CoA metabolic process
LQF05_RS13730	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LQF05_RS13735	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LQF05_RS13740	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LQF05_RS13745	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LQF05_RS13750	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LQF05_RS13770	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LQF05_RS13780	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LQF05_RS13785	COG0233	cytoplasmic translational termination
LQF05_RS13790	COG0528	UMP kinase activity
LQF05_RS13795	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LQF05_RS13800	COG0052	Belongs to the universal ribosomal protein uS2 family
LQF05_RS13805	COG0024	Methionine aminopeptidase
LQF05_RS13810	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LQF05_RS13815	COG1320	monovalent cation:proton antiporter activity
LQF05_RS13820	COG2212	antiporter activity
LQF05_RS13825	COG1863	multisubunit Na H antiporter MnhE subunit
LQF05_RS13830	COG0651	ATP synthesis coupled electron transport
LQF05_RS13835	COG1006	Multisubunit Na H antiporter MnhC subunit
LQF05_RS13840	COG2111	Na H antiporter
LQF05_RS13840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LQF05_RS13855	COG0259	pyridoxamine-phosphate oxidase activity
LQF05_RS13865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LQF05_RS13870	COG1199	ATP-dependent helicase activity
LQF05_RS13890	COG3012	SEC-C Motif Domain Protein
LQF05_RS13900	COG0583	DNA-binding transcription factor activity
LQF05_RS13910	COG0697	spore germination
LQF05_RS13915	COG3148	PFAM DTW domain containing protein
LQF05_RS13925	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LQF05_RS13930	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LQF05_RS13940	COG2137	regulation of response to DNA damage stimulus
LQF05_RS13945	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LQF05_RS13950	COG1546	Belongs to the CinA family
LQF05_RS13960	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LQF05_RS13965	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LQF05_RS13985	COG0438	transferase activity, transferring glycosyl groups
LQF05_RS13990	COG1295	ribonuclease BN
LQF05_RS14000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LQF05_RS14040	COG0784	Response regulator, receiver
LQF05_RS14040	COG2198	Histidine kinase
LQF05_RS14040	COG5002	protein histidine kinase activity
LQF05_RS14110	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LQF05_RS14125	COG2996	Protein conserved in bacteria
LQF05_RS14130	COG4993	Dehydrogenase
LQF05_RS14135	COG2133	pyrroloquinoline quinone binding
LQF05_RS14175	COG1201	RNA secondary structure unwinding
LQF05_RS14185	COG4221	oxidoreductase activity
LQF05_RS14195	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LQF05_RS14205	COG4935	Belongs to the peptidase S8 family
LQF05_RS14205	COG1404	Belongs to the peptidase S8 family
LQF05_RS14215	COG0367	asparagine synthase
LQF05_RS14220	COG0189	ligase activity
LQF05_RS14220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LQF05_RS14225	COG1363	Peptidase, m42
LQF05_RS14235	COG3089	Belongs to the UPF0270 family
LQF05_RS14255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LQF05_RS14260	COG3162	membrane
LQF05_RS14275	COG2853	Lipoprotein
LQF05_RS14285	COG1560	Kdo2-lipid A biosynthetic process
LQF05_RS14290	COG0850	regulation of cytokinetic process
LQF05_RS14295	COG2894	cell division
LQF05_RS14300	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LQF05_RS14305	COG0564	pseudouridine synthase activity
LQF05_RS14315	COG1362	aminopeptidase activity
LQF05_RS14330	COG2200	EAL domain
LQF05_RS14355	COG1555	photosystem II stabilization
LQF05_RS14365	COG1256	bacterial-type flagellum assembly
LQF05_RS14375	COG1706	bacterial-type flagellum-dependent cell motility
LQF05_RS14380	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LQF05_RS14385	COG4786	Flagellar basal body rod
LQF05_RS14390	COG4787	bacterial-type flagellum-dependent cell motility
LQF05_RS14410	COG1815	bacterial-type flagellum-dependent cell motility
LQF05_RS14415	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LQF05_RS14420	COG0784	Response regulator, receiver
LQF05_RS14420	COG0835	chemotaxis
LQF05_RS14440	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LQF05_RS14465	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
LQF05_RS14470	COG5016	pyruvate
LQF05_RS14470	COG0511	ligase activity, forming carbon-carbon bonds
LQF05_RS14475	COG3630	sodium ion export across plasma membrane
LQF05_RS14480	COG2239	Acts as a magnesium transporter
LQF05_RS14505	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LQF05_RS14510	COG0527	aspartate kinase activity
LQF05_RS14515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LQF05_RS14530	COG2983	Belongs to the UPF0260 family
LQF05_RS14540	COG3100	YcgL domain-containing protein
LQF05_RS14555	COG2067	long-chain fatty acid transport protein
LQF05_RS14585	COG0251	oxidation-reduction process
LQF05_RS14595	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LQF05_RS14605	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LQF05_RS14615	COG1492	cobalamin metabolic process
LQF05_RS14625	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LQF05_RS14635	COG0778	Nitroreductase
LQF05_RS14640	COG1797	cobyrinic acid a,c-diamide synthase activity
LQF05_RS14655	COG4206	TonB-dependent receptor
LQF05_RS14670	COG0791	NLP P60 protein
LQF05_RS14675	COG0791	NLP P60 protein
LQF05_RS14690	COG4890	Cyd operon protein YbgT
LQF05_RS14695	COG1294	oxidase, subunit
LQF05_RS14720	COG2818	Glycosylase
LQF05_RS14725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LQF05_RS14730	COG0037	tRNA processing
LQF05_RS14755	COG2814	Major facilitator Superfamily
LQF05_RS14760	COG4459	periplasmic nitrate reductase
LQF05_RS14770	COG0243	molybdopterin cofactor binding
LQF05_RS14780	COG3005	denitrification pathway
LQF05_RS14785	COG0717	Belongs to the dCTP deaminase family
LQF05_RS14790	COG1278	Cold shock
LQF05_RS14795	COG0489	protein tyrosine kinase activity
LQF05_RS14800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LQF05_RS14800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LQF05_RS14905	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LQF05_RS14910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LQF05_RS14925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LQF05_RS14930	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LQF05_RS14935	COG1414	Transcriptional regulator
LQF05_RS14940	COG0679	Auxin Efflux Carrier
LQF05_RS14945	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LQF05_RS14950	COG3485	protocatechuate 3,4-dioxygenase
LQF05_RS14955	COG3485	protocatechuate 3,4-dioxygenase
LQF05_RS14960	COG0583	DNA-binding transcription factor activity
LQF05_RS14985	COG1596	polysaccharide export
LQF05_RS14995	COG4464	protein tyrosine phosphatase activity
LQF05_RS15005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LQF05_RS15015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LQF05_RS15025	COG3475	LICD family
LQF05_RS15045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LQF05_RS15055	COG1051	belongs to the nudix hydrolase family
LQF05_RS15085	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LQF05_RS15100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LQF05_RS15115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LQF05_RS15125	COG2226	methyltransferase
LQF05_RS15130	COG0500	methyltransferase
LQF05_RS15140	COG0583	DNA-binding transcription factor activity
LQF05_RS15150	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LQF05_RS15155	COG1381	Involved in DNA repair and RecF pathway recombination
LQF05_RS15165	COG0571	ribonuclease III activity
LQF05_RS15180	COG0481	GTPase activity
LQF05_RS15185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LQF05_RS15225	COG0354	folic acid binding
LQF05_RS15240	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LQF05_RS15250	COG1024	Enoyl-CoA hydratase
LQF05_RS15265	COG4657	Part of a membrane complex involved in electron transport
LQF05_RS15270	COG2878	Part of a membrane complex involved in electron transport
LQF05_RS15280	COG4658	electron transport chain
LQF05_RS15285	COG4659	FMN binding
LQF05_RS15295	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LQF05_RS15305	COG0346	lactoylglutathione lyase activity
LQF05_RS15310	COG0137	argininosuccinate synthase activity
LQF05_RS15320	COG0418	dihydroorotase activity
LQF05_RS15325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LQF05_RS15340	COG3791	Glutathione-dependent formaldehyde-activating
LQF05_RS15355	COG0335	large ribosomal subunit rRNA binding
LQF05_RS15360	COG0336	Belongs to the RNA methyltransferase TrmD family
LQF05_RS15365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LQF05_RS15370	COG0228	four-way junction DNA binding
LQF05_RS15375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LQF05_RS15380	COG4137	Cytochrome C assembly protein
LQF05_RS15385	COG4536	flavin adenine dinucleotide binding
LQF05_RS15390	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LQF05_RS15415	COG3034	peptidoglycan biosynthetic process
LQF05_RS15425	COG0047	phosphoribosylformylglycinamidine synthase activity
LQF05_RS15425	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LQF05_RS15430	COG1126	abc transporter atp-binding protein
LQF05_RS15435	COG0765	amino acid transport
LQF05_RS15440	COG4597	amino acid ABC transporter
LQF05_RS15445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LQF05_RS15450	COG0400	carboxylic ester hydrolase activity
LQF05_RS15470	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LQF05_RS15475	COG0315	cyclic pyranopterin monophosphate synthase activity
LQF05_RS15480	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LQF05_RS15490	COG3022	response to hydroperoxide
LQF05_RS15505	COG0433	COG0433 Predicted ATPase
LQF05_RS15515	COG0788	formyltetrahydrofolate deformylase activity
LQF05_RS15525	COG2925	Exonuclease
LQF05_RS15550	COG0714	Associated with various cellular activities
LQF05_RS15575	COG0469	pyruvate kinase activity
LQF05_RS15595	COG4628	conserved protein (DUF2132)
LQF05_RS15600	COG0693	protein deglycase activity
LQF05_RS15605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LQF05_RS15645	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS15650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LQF05_RS15665	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LQF05_RS15675	COG1309	transcriptional regulator
LQF05_RS15680	COG0386	Belongs to the glutathione peroxidase family
LQF05_RS15690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LQF05_RS15700	COG0204	Acyl-transferase
LQF05_RS15710	COG2205	protein histidine kinase activity
LQF05_RS15710	COG0784	Response regulator, receiver
LQF05_RS15715	COG2885	chlorophyll binding
LQF05_RS15720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LQF05_RS15725	COG4191	Histidine kinase
LQF05_RS15725	COG0784	Response regulator, receiver
LQF05_RS15730	COG0318	PFAM AMP-dependent synthetase and ligase
LQF05_RS15735	COG1280	lysine exporter protein (LysE YggA)
LQF05_RS15740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LQF05_RS15745	COG2813	Specifically methylates the guanine in position
LQF05_RS15750	COG2119	membrane
LQF05_RS15760	COG0501	Belongs to the peptidase M48B family
LQF05_RS15765	COG0840	transmembrane signaling receptor activity
LQF05_RS15820	COG0659	secondary active sulfate transmembrane transporter activity
LQF05_RS15825	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS15850	COG1285	pathogenesis
LQF05_RS15895	COG1181	Belongs to the D-alanine--D-alanine ligase family
LQF05_RS15900	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LQF05_RS15905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LQF05_RS15910	COG0772	Belongs to the SEDS family
LQF05_RS15915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LQF05_RS15920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LQF05_RS15925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LQF05_RS15930	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LQF05_RS15945	COG0275	rRNA processing
LQF05_RS15970	COG0792	nuclease activity
LQF05_RS15975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LQF05_RS15980	COG2823	Periplasmic or secreted lipoprotein
LQF05_RS15985	COG2969	positive regulation of protein catabolic process
LQF05_RS15990	COG0625	glutathione transferase activity
LQF05_RS15995	COG2857	Cytochrome c1
LQF05_RS16000	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LQF05_RS16005	COG0723	plastoquinol--plastocyanin reductase activity
LQF05_RS16010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LQF05_RS16015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LQF05_RS16020	COG0667	Aldo Keto reductase
LQF05_RS16035	COG0237	dephospho-CoA kinase activity
LQF05_RS16040	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LQF05_RS16065	COG0175	sulfate reduction
LQF05_RS16075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LQF05_RS16080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LQF05_RS16090	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LQF05_RS16095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LQF05_RS16120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LQF05_RS16125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LQF05_RS16130	COG1127	ABC transporter
LQF05_RS16140	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LQF05_RS16155	COG1137	ATPase activity
LQF05_RS16160	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LQF05_RS16175	COG1660	Displays ATPase and GTPase activities
LQF05_RS16180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LQF05_RS16185	COG0312	modulator of DNA gyrase
LQF05_RS16195	COG0312	modulator of DNA gyrase
LQF05_RS16200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LQF05_RS16210	COG1530	ribonuclease E activity
LQF05_RS16230	COG1792	Involved in formation and maintenance of cell shape
LQF05_RS16235	COG1077	Cell shape determining protein MreB Mrl
LQF05_RS16240	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LQF05_RS16250	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LQF05_RS16265	COG0530	calcium, potassium:sodium antiporter activity
LQF05_RS16280	COG0739	heme binding
LQF05_RS16290	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LQF05_RS16305	COG4771	TonB-dependent receptor
LQF05_RS16325	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LQF05_RS16330	COG4774	siderophore transport
LQF05_RS16335	COG3128	pkhd-type hydroxylase
LQF05_RS16345	COG0019	diaminopimelate decarboxylase activity
LQF05_RS16350	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LQF05_RS16360	COG4993	Dehydrogenase
LQF05_RS16365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LQF05_RS16365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LQF05_RS16365	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LQF05_RS16370	COG1105	Belongs to the carbohydrate kinase PfkB family
LQF05_RS16375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LQF05_RS16375	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LQF05_RS16390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LQF05_RS16420	COG0534	Mate efflux family protein
LQF05_RS16435	COG0023	Translation Initiation Factor
LQF05_RS16440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LQF05_RS16445	COG4968	Prepilin-type N-terminal cleavage methylation domain
LQF05_RS16480	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LQF05_RS16485	COG1047	Peptidyl-prolyl cis-trans
LQF05_RS16490	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LQF05_RS16495	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LQF05_RS16500	COG0196	riboflavin kinase activity
LQF05_RS16510	COG0268	Binds directly to 16S ribosomal RNA
LQF05_RS16515	COG3045	CreA protein
LQF05_RS16520	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LQF05_RS16525	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LQF05_RS16530	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LQF05_RS16535	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LQF05_RS16540	COG0142	geranyltranstransferase activity
LQF05_RS16550	COG0545	Peptidyl-prolyl cis-trans isomerase
LQF05_RS16560	COG3046	protein related to deoxyribodipyrimidine photolyase
LQF05_RS16570	COG2862	Uncharacterized protein family, UPF0114
LQF05_RS16580	COG1067	ATP-dependent peptidase activity
LQF05_RS16590	COG1970	mechanosensitive ion channel activity
LQF05_RS16595	COG2841	Protein conserved in bacteria
LQF05_RS16615	COG2020	methyltransferase activity
LQF05_RS16620	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LQF05_RS16625	COG0488	(ABC) transporter
LQF05_RS16660	COG2813	Specifically methylates the guanine in position
LQF05_RS16665	COG0789	Transcriptional regulator
LQF05_RS16690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LQF05_RS16695	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LQF05_RS16700	COG2080	2 iron, 2 sulfur cluster binding
LQF05_RS16705	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LQF05_RS16710	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LQF05_RS16710	COG3608	succinylglutamate desuccinylase aspartoacylase
LQF05_RS16720	COG2252	PERMEase
LQF05_RS16725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LQF05_RS16730	COG1368	sulfuric ester hydrolase activity
LQF05_RS16740	COG3642	lipopolysaccharide core region biosynthetic process
LQF05_RS16750	COG0642	Histidine kinase
LQF05_RS16760	COG1368	sulfuric ester hydrolase activity
LQF05_RS16815	COG3038	cytochrome b561
LQF05_RS16825	COG0521	Mo-molybdopterin cofactor biosynthetic process
LQF05_RS16840	COG2181	nitrate reductase activity
LQF05_RS16845	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LQF05_RS16850	COG1140	nitrate reductase beta subunit
LQF05_RS16855	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LQF05_RS16860	COG2223	nitrite transmembrane transporter activity
LQF05_RS16870	COG2223	nitrite transmembrane transporter activity
LQF05_RS16875	COG3850	Histidine kinase
LQF05_RS16880	COG2197	response regulator
LQF05_RS16905	COG3210	domain, Protein
LQF05_RS16930	COG2321	neutral zinc metallopeptidase
LQF05_RS16940	COG1946	Acyl-CoA thioesterase
LQF05_RS16950	COG0123	including yeast histone deacetylase and acetoin utilization protein
LQF05_RS16975	COG0513	Belongs to the DEAD box helicase family
LQF05_RS16980	COG4651	solute:proton antiporter activity
LQF05_RS16980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LQF05_RS17000	COG0733	neurotransmitter:sodium symporter activity
LQF05_RS17005	COG0625	glutathione transferase activity
LQF05_RS17015	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LQF05_RS17025	COG0733	neurotransmitter:sodium symporter activity
LQF05_RS17040	COG1522	sequence-specific DNA binding
LQF05_RS17050	COG2031	fatty acid transporter
LQF05_RS17055	COG2610	gluconate transmembrane transporter activity
LQF05_RS17060	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS17065	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LQF05_RS17070	COG1040	competence protein
LQF05_RS17130	COG0420	3'-5' exonuclease activity
LQF05_RS17140	COG4206	TonB-dependent receptor
LQF05_RS17155	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LQF05_RS17160	COG3577	Aspartyl protease
LQF05_RS17165	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LQF05_RS17175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LQF05_RS17180	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LQF05_RS17195	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LQF05_RS17195	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LQF05_RS17210	COG2264	protein methyltransferase activity
LQF05_RS17220	COG0425	Belongs to the sulfur carrier protein TusA family
LQF05_RS17225	COG2391	methyltransferase activity
LQF05_RS17230	COG3118	belongs to the thioredoxin family
LQF05_RS17245	COG4181	ATPase activity
LQF05_RS17270	COG0848	biopolymer transport protein
LQF05_RS17275	COG0811	peptide transport
LQF05_RS17280	COG0811	peptide transport
LQF05_RS17290	COG3047	cAMP biosynthetic process
LQF05_RS17295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LQF05_RS17310	COG2814	Major facilitator Superfamily
LQF05_RS17325	COG0203	ribosomal protein L17
LQF05_RS17330	COG0202	RNA polymerase activity
LQF05_RS17335	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LQF05_RS17340	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LQF05_RS17345	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LQF05_RS17350	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LQF05_RS17360	COG0200	Binds to the 23S rRNA
LQF05_RS17365	COG1841	ribosomal large subunit assembly
LQF05_RS17370	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LQF05_RS17380	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LQF05_RS17385	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LQF05_RS17390	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LQF05_RS17395	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LQF05_RS17400	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LQF05_RS17405	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LQF05_RS17410	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LQF05_RS17415	COG0255	Belongs to the universal ribosomal protein uL29 family
LQF05_RS17420	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LQF05_RS17425	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LQF05_RS17430	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LQF05_RS17435	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LQF05_RS17440	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LQF05_RS17445	COG0089	rRNA binding
LQF05_RS17450	COG0088	Forms part of the polypeptide exit tunnel
LQF05_RS17455	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LQF05_RS17460	COG0051	transcription antitermination factor activity, RNA binding
LQF05_RS17465	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LQF05_RS17470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LQF05_RS17475	COG0049	tRNA binding
LQF05_RS17480	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LQF05_RS17485	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LQF05_RS17490	COG0085	RNA polymerase activity
LQF05_RS17495	COG0222	ribosome binding
LQF05_RS17500	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LQF05_RS17505	COG0081	regulation of translation
LQF05_RS17510	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LQF05_RS17530	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LQF05_RS17555	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LQF05_RS17560	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LQF05_RS17560	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LQF05_RS17590	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LQF05_RS17595	COG0739	heme binding
LQF05_RS17600	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LQF05_RS17605	COG0316	Belongs to the HesB IscA family
LQF05_RS17610	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LQF05_RS17615	COG1981	membrane
LQF05_RS17625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LQF05_RS17630	COG0537	adenosine 5'-monophosphoramidase activity
LQF05_RS17635	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LQF05_RS17640	COG1765	OsmC-like protein
LQF05_RS17650	COG0134	indole-3-glycerol-phosphate synthase activity
LQF05_RS17655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LQF05_RS17660	COG0512	Glutamine amidotransferase of anthranilate synthase
LQF05_RS17670	COG0546	phosphoglycolate phosphatase activity
LQF05_RS17675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LQF05_RS17680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LQF05_RS17690	COG1177	transmembrane transport
LQF05_RS17695	COG1176	ABC-type spermidine putrescine transport system, permease component I
LQF05_RS17705	COG3842	ATPase activity
LQF05_RS17710	COG2197	response regulator
LQF05_RS17725	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LQF05_RS17730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LQF05_RS17740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LQF05_RS17745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LQF05_RS17750	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LQF05_RS17755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LQF05_RS17760	COG2967	ApaG domain
LQF05_RS17765	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LQF05_RS17770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LQF05_RS17775	COG2766	serine protein kinase
LQF05_RS17780	COG2718	Belongs to the UPF0229 family
LQF05_RS17785	COG2719	SpoVR family
LQF05_RS17790	COG0617	tRNA 3'-terminal CCA addition
LQF05_RS17805	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LQF05_RS17810	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LQF05_RS17815	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LQF05_RS17820	COG0358	DNA primase activity
LQF05_RS17825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LQF05_RS17835	COG0471	metal ion transport
LQF05_RS17835	COG3273	potassium ion transport
LQF05_RS17840	COG2873	o-acetylhomoserine
LQF05_RS17845	COG3118	belongs to the thioredoxin family
LQF05_RS17860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LQF05_RS17865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LQF05_RS17890	COG2986	histidine ammonia-lyase
LQF05_RS17930	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS17935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LQF05_RS17950	COG0583	DNA-binding transcription factor activity
LQF05_RS17955	COG2814	Major facilitator Superfamily
LQF05_RS17965	COG0493	'glutamate synthase
LQF05_RS17970	COG0070	glutamate synthase
LQF05_RS17970	COG0067	glutamate synthase
LQF05_RS17970	COG0069	glutamate synthase activity
LQF05_RS17980	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LQF05_RS17985	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LQF05_RS18020	COG0281	malic enzyme
LQF05_RS18030	COG0254	rRNA binding
LQF05_RS18035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LQF05_RS18040	COG0018	arginyl-trna synthetase
LQF05_RS18055	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LQF05_RS18070	COG0248	Ppx GppA phosphatase
LQF05_RS18075	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LQF05_RS18085	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LQF05_RS18100	COG1671	Belongs to the UPF0178 family
LQF05_RS18105	COG1280	lysine exporter protein (LysE YggA)
LQF05_RS18110	COG0861	Integral membrane protein TerC family
LQF05_RS18120	COG0488	(ABC) transporter
LQF05_RS18140	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LQF05_RS18160	COG0181	hydroxymethylbilane synthase activity
LQF05_RS18170	COG3275	phosphorelay sensor kinase activity
LQF05_RS18175	COG0165	Argininosuccinate lyase
LQF05_RS18210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LQF05_RS18215	COG1965	Belongs to the frataxin family
LQF05_RS18230	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LQF05_RS18240	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LQF05_RS18255	COG0432	Pfam Uncharacterised protein family UPF0047
LQF05_RS18260	COG0004	ammonium transporteR
LQF05_RS18265	COG0004	ammonium transporteR
LQF05_RS18270	COG0347	Belongs to the P(II) protein family
LQF05_RS18280	COG0606	chelatase, subunit chli
LQF05_RS18285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LQF05_RS18295	COG0210	DNA helicase
LQF05_RS18300	COG1272	protein, Hemolysin III
LQF05_RS18305	COG1414	Transcriptional regulator
LQF05_RS18315	COG1454	alcohol dehydrogenase
LQF05_RS18325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LQF05_RS18330	COG0366	Alpha amylase catalytic
LQF05_RS18345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LQF05_RS18365	COG0251	oxidation-reduction process
LQF05_RS18370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LQF05_RS18380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LQF05_RS18385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LQF05_RS18405	COG1250	3-hydroxyacyl-CoA dehydrogenase
LQF05_RS18420	COG2003	Belongs to the UPF0758 family
LQF05_RS18425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LQF05_RS18430	COG0756	dUTP diphosphatase activity
LQF05_RS18440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LQF05_RS18455	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LQF05_RS18460	COG0708	Exodeoxyribonuclease III
LQF05_RS18470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LQF05_RS18475	COG1561	YicC-like family, N-terminal region
LQF05_RS18485	COG1758	RNA polymerase activity
LQF05_RS18490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LQF05_RS18510	COG2080	2 iron, 2 sulfur cluster binding
LQF05_RS18530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LQF05_RS18550	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LQF05_RS18555	COG1704	LemA family
LQF05_RS18560	COG0583	DNA-binding transcription factor activity
LQF05_RS18565	COG0604	alcohol dehydrogenase
LQF05_RS18575	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS18580	COG0583	DNA-binding transcription factor activity
LQF05_RS18605	COG1620	l-lactate permease
LQF05_RS18610	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LQF05_RS18615	COG3193	protein, possibly involved in utilization of glycolate and propanediol
LQF05_RS18620	COG0247	lactate metabolic process
LQF05_RS18625	COG0277	FAD linked oxidase domain protein
LQF05_RS18630	COG0277	FAD linked oxidase domain protein
LQF05_RS18635	COG2186	Transcriptional regulator
LQF05_RS18640	COG3161	chorismate lyase activity
LQF05_RS18645	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LQF05_RS18660	COG1253	flavin adenine dinucleotide binding
LQF05_RS18695	COG0739	heme binding
LQF05_RS18715	COG0411	ABC transporter
LQF05_RS18725	COG0559	Belongs to the binding-protein-dependent transport system permease family
LQF05_RS18735	COG1192	Involved in chromosome partitioning
LQF05_RS18740	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LQF05_RS18745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LQF05_RS18750	COG0730	response to heat
LQF05_RS18765	COG0494	nUDIX hydrolase
LQF05_RS18785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LQF05_RS18790	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LQF05_RS18810	COG0179	Fumarylacetoacetate (FAA) hydrolase
LQF05_RS18815	COG0277	FAD linked oxidase domain protein
LQF05_RS18820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LQF05_RS18845	COG2197	response regulator
LQF05_RS18885	COG0651	ATP synthesis coupled electron transport
LQF05_RS18890	COG0651	ATP synthesis coupled electron transport
LQF05_RS18910	COG1320	monovalent cation:proton antiporter activity
LQF05_RS18925	COG1966	Carbon starvation protein
LQF05_RS18935	COG0003	Pfam Anion-transporting ATPase
LQF05_RS18940	COG1028	Short-chain dehydrogenase reductase Sdr
LQF05_RS18955	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LQF05_RS18960	COG5001	Diguanylate cyclase
LQF05_RS18985	COG4807	Protein conserved in bacteria
LQF05_RS18990	COG2204	response regulator
LQF05_RS19015	COG4565	transcriptional regulatory protein
LQF05_RS19020	COG3290	protein histidine kinase activity
LQF05_RS19025	COG3493	citrate carrier protein
LQF05_RS19035	COG1217	gtp-binding protein TYPA
LQF05_RS19040	COG0301	tRNA thio-modification
LQF05_RS19040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LQF05_RS19060	COG3852	Histidine kinase
LQF05_RS19080	COG0243	molybdopterin cofactor binding
LQF05_RS19090	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LQF05_RS19100	COG0840	transmembrane signaling receptor activity
LQF05_RS19110	COG2226	methyltransferase
LQF05_RS19120	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LQF05_RS19125	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LQF05_RS19130	COG0140	phosphoribosyl-ATP diphosphatase activity
LQF05_RS19135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LQF05_RS19140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LQF05_RS19160	COG1490	D-aminoacyl-tRNA deacylase activity
LQF05_RS19190	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LQF05_RS19195	COG0058	SHG alpha-glucan phosphorylase activity
LQF05_RS19210	COG1218	3'(2'),5'-bisphosphate nucleotidase
LQF05_RS19215	COG0494	nUDIX hydrolase
LQF05_RS19220	COG1011	Hydrolase
LQF05_RS19225	COG0784	Response regulator, receiver
LQF05_RS19225	COG4191	Histidine kinase
LQF05_RS19230	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LQF05_RS19245	COG1454	alcohol dehydrogenase
LQF05_RS19250	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS19255	COG1250	3-hydroxyacyl-CoA dehydrogenase
LQF05_RS19255	COG1024	Enoyl-CoA hydratase
LQF05_RS19265	COG1366	Belongs to the anti-sigma-factor antagonist family
LQF05_RS19270	COG1366	Belongs to the anti-sigma-factor antagonist family
LQF05_RS19275	COG2172	sigma factor antagonist activity
LQF05_RS19285	COG2205	protein histidine kinase activity
LQF05_RS19290	COG0784	Response regulator, receiver
LQF05_RS19290	COG4191	Histidine kinase
LQF05_RS19315	COG0667	Aldo Keto reductase
LQF05_RS19330	COG0840	transmembrane signaling receptor activity
LQF05_RS19335	COG0514	ATP-dependent DNA helicase (RecQ)
LQF05_RS19345	COG0778	Nitroreductase
LQF05_RS19355	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LQF05_RS19365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LQF05_RS19370	COG0189	ligase activity
LQF05_RS19370	COG4067	protein conserved in archaea
LQF05_RS19375	COG0189	ligase activity
LQF05_RS19390	COG2183	response to ionizing radiation
LQF05_RS19400	COG2918	glutathione biosynthetic process
LQF05_RS19420	COG0306	phosphate transporter
LQF05_RS19425	COG1392	Phosphate transport regulator
LQF05_RS19435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LQF05_RS19445	COG2989	Protein conserved in bacteria
LQF05_RS19460	COG1764	response to oxidative stress
LQF05_RS19465	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LQF05_RS19490	COG2814	Major facilitator Superfamily
LQF05_RS19495	COG0583	DNA-binding transcription factor activity
LQF05_RS19520	COG1116	anion transmembrane transporter activity
LQF05_RS19525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LQF05_RS19530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LQF05_RS19535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LQF05_RS19540	COG0431	NADPH-dependent FMN reductase
LQF05_RS19545	COG0450	alkyl hydroperoxide reductase
LQF05_RS19555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LQF05_RS19560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LQF05_RS19570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LQF05_RS19585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LQF05_RS19600	COG2175	clavaminate synthase activity
LQF05_RS19605	COG3829	transcription factor binding
LQF05_RS19615	COG5583	Uncharacterized small protein (DUF2292)
LQF05_RS19620	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LQF05_RS19630	COG4208	sulfate ABC transporter
LQF05_RS19640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LQF05_RS19670	COG2205	protein histidine kinase activity
LQF05_RS19675	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LQF05_RS19675	COG1082	Xylose isomerase domain protein TIM barrel
LQF05_RS19685	COG0583	DNA-binding transcription factor activity
LQF05_RS19695	COG1301	dicarboxylic acid transport
LQF05_RS19705	COG1115	amino acid carrier protein
LQF05_RS19710	COG0252	asparaginase activity
LQF05_RS19725	COG2066	Belongs to the glutaminase family
LQF05_RS19740	COG5016	pyruvate
LQF05_RS19740	COG0511	ligase activity, forming carbon-carbon bonds
LQF05_RS19745	COG0439	Biotin carboxylase
LQF05_RS19750	COG0583	DNA-binding transcription factor activity
LQF05_RS19760	COG1737	Transcriptional regulator
LQF05_RS19760	COG0837	glucose binding
LQF05_RS19765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LQF05_RS19775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LQF05_RS19780	COG1917	Cupin 2, conserved barrel domain protein
LQF05_RS19785	COG5285	phytanoyl-CoA dioxygenase
LQF05_RS19790	COG0527	aspartate kinase activity
LQF05_RS19795	COG2841	Protein conserved in bacteria
LQF05_RS19800	COG0826	peptidase U32
LQF05_RS19810	COG0210	DNA helicase
LQF05_RS19815	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LQF05_RS19830	COG1764	response to oxidative stress
LQF05_RS19845	COG0437	4 iron, 4 sulfur cluster binding
LQF05_RS19850	COG2864	formate dehydrogenase
LQF05_RS19855	COG3058	Necessary for formate dehydrogenase activity
LQF05_RS19860	COG1921	L-seryl-tRNASec selenium transferase activity
LQF05_RS19865	COG3276	selenocysteine insertion sequence binding
LQF05_RS19885	COG0509	glycine decarboxylation via glycine cleavage system
LQF05_RS19895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LQF05_RS19900	COG0589	response to stress
LQF05_RS19910	COG4191	Histidine kinase
LQF05_RS19915	COG2204	response regulator
LQF05_RS19920	COG4941	Belongs to the sigma-70 factor family
LQF05_RS19925	COG3795	YCII-related domain
LQF05_RS19950	COG0784	Response regulator, receiver
LQF05_RS19950	COG4191	Histidine kinase
LQF05_RS19955	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS19960	COG2706	6-phosphogluconolactonase activity
LQF05_RS20000	COG0583	DNA-binding transcription factor activity
LQF05_RS20005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LQF05_RS20080	COG2249	NAD(P)H dehydrogenase (quinone) activity
LQF05_RS20090	COG2207	Transcriptional regulator
LQF05_RS20160	COG1611	Belongs to the LOG family
LQF05_RS20175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LQF05_RS20180	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LQF05_RS20185	COG0318	PFAM AMP-dependent synthetase and ligase
LQF05_RS20205	COG2814	Major facilitator Superfamily
LQF05_RS20225	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS20230	COG1960	acyl-CoA dehydrogenase activity
LQF05_RS20235	COG1250	3-hydroxyacyl-CoA dehydrogenase
LQF05_RS20235	COG1024	Enoyl-CoA hydratase
LQF05_RS20245	COG1012	belongs to the aldehyde dehydrogenase family
LQF05_RS20250	COG3909	cytochrome
LQF05_RS20300	COG0515	serine threonine protein kinase
LQF05_RS20335	COG0840	transmembrane signaling receptor activity
LQF05_RS20350	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LQF05_RS20370	COG3052	prosthetic group binding
LQF05_RS20375	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LQF05_RS20385	COG4221	oxidoreductase activity
LQF05_RS20390	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LQF05_RS20405	COG2358	TRAP transporter, solute receptor (TAXI family
LQF05_RS20445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LQF05_RS20455	COG3360	Dodecin
LQF05_RS20460	COG0625	glutathione transferase activity
LQF05_RS20480	COG0737	Belongs to the 5'-nucleotidase family
LQF05_RS20495	COG3340	Belongs to the peptidase S51 family
LQF05_RS20500	COG1132	(ABC) transporter
LQF05_RS20550	COG0583	DNA-binding transcription factor activity
LQF05_RS20585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LQF05_RS20590	COG0339	signal peptide processing
LQF05_RS20620	COG0659	secondary active sulfate transmembrane transporter activity
LQF05_RS20630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LQF05_RS20635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LQF05_RS20640	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
LQF05_RS20670	COG0109	protoheme IX farnesyltransferase activity
LQF05_RS20695	COG1595	DNA-templated transcription, initiation
LQF05_RS20710	COG0523	cobalamin synthesis protein
LQF05_RS20725	COG4251	negative regulation of phosphorylation
LQF05_RS20730	COG0784	Response regulator, receiver
LQF05_RS20745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LQF05_RS20750	COG1349	DNA-binding transcription factor activity
LQF05_RS20760	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LQF05_RS20765	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LQF05_RS20770	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LQF05_RS20775	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LQF05_RS20780	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LQF05_RS20785	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LQF05_RS20790	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LQF05_RS20800	COG0356	it plays a direct role in the translocation of protons across the membrane
LQF05_RS20805	COG3312	ion transport
LQF05_RS20810	COG1475	DNA binding
LQF05_RS20815	COG1192	Involved in chromosome partitioning
LQF05_RS20820	COG0357	Ribosomal RNA small subunit methyltransferase G
LQF05_RS20825	COG0445	tRNA wobble uridine modification
LQF05_RS20830	COG1320	monovalent cation:proton antiporter activity
LQF05_RS20845	COG0651	ATP synthesis coupled electron transport
LQF05_RS20850	COG1006	Multisubunit Na H antiporter MnhC subunit
LQF05_RS20855	COG2111	Na H antiporter
LQF05_RS20860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LQF05_RS20860	COG2111	Na H antiporter
LQF05_RS20865	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LQF05_RS20870	COG0706	membrane insertase activity
LQF05_RS20875	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LQF05_RS20880	COG0594	ribonuclease P activity
LQF05_RS20885	COG0230	Belongs to the bacterial ribosomal protein bL34 family