locus-tag	class	description
IM687_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IM687_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IM687_RS00030	COG3706	GGDEF domain
IM687_RS00045	COG0751	glycine-tRNA ligase activity
IM687_RS00055	COG2818	Glycosylase
IM687_RS00075	COG1126	abc transporter atp-binding protein
IM687_RS00080	COG0765	amino acid transport
IM687_RS00085	COG0765	amino acid transport
IM687_RS00090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM687_RS00095	COG0569	domain protein
IM687_RS00100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IM687_RS00105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IM687_RS00110	COG0242	peptide deformylase activity
IM687_RS00120	COG0758	DNA mediated transformation
IM687_RS00125	COG0009	L-threonylcarbamoyladenylate synthase
IM687_RS00135	COG0408	coproporphyrinogen oxidase activity
IM687_RS00140	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IM687_RS00155	COG1686	Belongs to the peptidase S11 family
IM687_RS00195	COG2011	ABC-type metal ion transport system permease component
IM687_RS00210	COG1451	nucleotide metabolic process
IM687_RS00215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM687_RS00220	COG1121	(ABC) transporter
IM687_RS00225	COG0735	belongs to the Fur family
IM687_RS00235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IM687_RS00240	COG1012	belongs to the aldehyde dehydrogenase family
IM687_RS00260	COG0745	RESPONSE REGULATOR receiver
IM687_RS00265	COG5002	protein histidine kinase activity
IM687_RS00275	COG0745	RESPONSE REGULATOR receiver
IM687_RS00280	COG5002	protein histidine kinase activity
IM687_RS00285	COG0745	RESPONSE REGULATOR receiver
IM687_RS00290	COG4191	Histidine kinase
IM687_RS00300	COG3706	GGDEF domain
IM687_RS00310	COG2957	Belongs to the agmatine deiminase family
IM687_RS00325	COG0174	glutamine synthetase
IM687_RS00330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IM687_RS00335	COG0174	glutamine synthetase
IM687_RS00360	COG3842	ATPase activity
IM687_RS00365	COG1176	ABC-type spermidine putrescine transport system, permease component I
IM687_RS00370	COG1177	transmembrane transport
IM687_RS00440	COG0842	Transport permease protein
IM687_RS00445	COG0842	Transport permease protein
IM687_RS00445	COG1129	ABC transporter
IM687_RS00450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM687_RS00465	COG1127	ABC transporter
IM687_RS00470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IM687_RS00475	COG0753	catalase activity
IM687_RS00480	COG2010	Cytochrome c
IM687_RS00615	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
IM687_RS00620	COG3909	cytochrome
IM687_RS00625	COG1012	belongs to the aldehyde dehydrogenase family
IM687_RS00635	COG1024	Enoyl-CoA hydratase
IM687_RS00635	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM687_RS00640	COG1960	acyl-CoA dehydrogenase activity
IM687_RS00645	COG1960	acyl-CoA dehydrogenase activity
IM687_RS00650	COG2814	Major facilitator Superfamily
IM687_RS00670	COG0318	PFAM AMP-dependent synthetase and ligase
IM687_RS00675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IM687_RS00680	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IM687_RS00695	COG1611	Belongs to the LOG family
IM687_RS00770	COG2207	Transcriptional regulator
IM687_RS00780	COG2249	NAD(P)H dehydrogenase (quinone) activity
IM687_RS00855	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IM687_RS00860	COG0583	DNA-binding transcription factor activity
IM687_RS00910	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IM687_RS00955	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IM687_RS00985	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IM687_RS01010	COG1191	sigma factor activity
IM687_RS01015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IM687_RS01035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IM687_RS01045	COG1815	bacterial-type flagellum-dependent cell motility
IM687_RS01050	COG1558	bacterial-type flagellum-dependent cell motility
IM687_RS01055	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IM687_RS01065	COG4787	bacterial-type flagellum-dependent cell motility
IM687_RS01070	COG4786	Flagellar basal body rod
IM687_RS01080	COG1706	bacterial-type flagellum-dependent cell motility
IM687_RS01085	COG0741	lytic transglycosylase activity
IM687_RS01090	COG1256	bacterial-type flagellum assembly
IM687_RS01090	COG4786	Flagellar basal body rod
IM687_RS01105	COG2706	6-phosphogluconolactonase activity
IM687_RS01110	COG1960	acyl-CoA dehydrogenase activity
IM687_RS01115	COG0784	Response regulator, receiver
IM687_RS01115	COG4191	Histidine kinase
IM687_RS01140	COG3795	YCII-related domain
IM687_RS01145	COG4941	Belongs to the sigma-70 factor family
IM687_RS01150	COG2204	response regulator
IM687_RS01155	COG4191	Histidine kinase
IM687_RS01165	COG0589	response to stress
IM687_RS01170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IM687_RS01180	COG0509	glycine decarboxylation via glycine cleavage system
IM687_RS01275	COG3276	selenocysteine insertion sequence binding
IM687_RS01280	COG1921	L-seryl-tRNASec selenium transferase activity
IM687_RS01285	COG3058	Necessary for formate dehydrogenase activity
IM687_RS01290	COG2864	formate dehydrogenase
IM687_RS01295	COG0437	4 iron, 4 sulfur cluster binding
IM687_RS01310	COG1764	response to oxidative stress
IM687_RS01325	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IM687_RS01330	COG0210	DNA helicase
IM687_RS01340	COG0826	peptidase U32
IM687_RS01345	COG2841	Protein conserved in bacteria
IM687_RS01350	COG0527	aspartate kinase activity
IM687_RS01355	COG5285	phytanoyl-CoA dioxygenase
IM687_RS01360	COG1917	Cupin 2, conserved barrel domain protein
IM687_RS01365	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IM687_RS01375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IM687_RS01380	COG0837	glucose binding
IM687_RS01380	COG1737	Transcriptional regulator
IM687_RS01390	COG0583	DNA-binding transcription factor activity
IM687_RS01395	COG0439	Biotin carboxylase
IM687_RS01400	COG0511	ligase activity, forming carbon-carbon bonds
IM687_RS01400	COG5016	pyruvate
IM687_RS01415	COG2066	Belongs to the glutaminase family
IM687_RS01430	COG0252	asparaginase activity
IM687_RS01435	COG1115	amino acid carrier protein
IM687_RS01445	COG1301	dicarboxylic acid transport
IM687_RS01455	COG0583	DNA-binding transcription factor activity
IM687_RS01465	COG1082	Xylose isomerase domain protein TIM barrel
IM687_RS01465	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IM687_RS01470	COG2205	protein histidine kinase activity
IM687_RS01500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM687_RS01510	COG4208	sulfate ABC transporter
IM687_RS01520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IM687_RS01525	COG5583	Uncharacterized small protein (DUF2292)
IM687_RS01535	COG0450	alkyl hydroperoxide reductase
IM687_RS01540	COG0431	NADPH-dependent FMN reductase
IM687_RS01545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM687_RS01550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM687_RS01555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM687_RS01560	COG1116	anion transmembrane transporter activity
IM687_RS01585	COG0583	DNA-binding transcription factor activity
IM687_RS01590	COG2814	Major facilitator Superfamily
IM687_RS01615	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IM687_RS01620	COG1764	response to oxidative stress
IM687_RS01635	COG2989	Protein conserved in bacteria
IM687_RS01645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IM687_RS01655	COG1392	Phosphate transport regulator
IM687_RS01660	COG0306	phosphate transporter
IM687_RS01680	COG2918	glutathione biosynthetic process
IM687_RS01690	COG2183	response to ionizing radiation
IM687_RS01695	COG0457	Tetratricopeptide repeat
IM687_RS01695	COG3118	belongs to the thioredoxin family
IM687_RS01700	COG1215	transferase activity, transferring glycosyl groups
IM687_RS01705	COG1215	transferase activity, transferring glycosyl groups
IM687_RS01710	COG1192	Involved in chromosome partitioning
IM687_RS01720	COG2194	sulfuric ester hydrolase activity
IM687_RS01750	COG0189	ligase activity
IM687_RS01755	COG4067	protein conserved in archaea
IM687_RS01755	COG0189	ligase activity
IM687_RS01760	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IM687_RS01770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IM687_RS01780	COG0778	Nitroreductase
IM687_RS01790	COG0514	ATP-dependent DNA helicase (RecQ)
IM687_RS01795	COG0840	transmembrane signaling receptor activity
IM687_RS01810	COG0019	diaminopimelate decarboxylase activity
IM687_RS01825	COG0747	negative chemotaxis
IM687_RS01835	COG0667	Aldo Keto reductase
IM687_RS01860	COG4191	Histidine kinase
IM687_RS01860	COG0784	Response regulator, receiver
IM687_RS01865	COG2205	protein histidine kinase activity
IM687_RS01875	COG2172	sigma factor antagonist activity
IM687_RS01880	COG1366	Belongs to the anti-sigma-factor antagonist family
IM687_RS01885	COG1366	Belongs to the anti-sigma-factor antagonist family
IM687_RS01895	COG1024	Enoyl-CoA hydratase
IM687_RS01895	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM687_RS01900	COG1960	acyl-CoA dehydrogenase activity
IM687_RS01905	COG1454	alcohol dehydrogenase
IM687_RS01920	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IM687_RS01925	COG4191	Histidine kinase
IM687_RS01925	COG0784	Response regulator, receiver
IM687_RS01930	COG1011	Hydrolase
IM687_RS01935	COG0494	nUDIX hydrolase
IM687_RS01940	COG1218	3'(2'),5'-bisphosphate nucleotidase
IM687_RS01955	COG0058	SHG alpha-glucan phosphorylase activity
IM687_RS01960	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IM687_RS01990	COG1490	D-aminoacyl-tRNA deacylase activity
IM687_RS02010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM687_RS02015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM687_RS02020	COG0140	phosphoribosyl-ATP diphosphatase activity
IM687_RS02025	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IM687_RS02030	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IM687_RS02040	COG2226	methyltransferase
IM687_RS02050	COG0840	transmembrane signaling receptor activity
IM687_RS02060	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IM687_RS02070	COG0243	molybdopterin cofactor binding
IM687_RS02090	COG3852	Histidine kinase
IM687_RS02110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM687_RS02110	COG0301	tRNA thio-modification
IM687_RS02115	COG1217	gtp-binding protein TYPA
IM687_RS02125	COG3493	citrate carrier protein
IM687_RS02130	COG3290	protein histidine kinase activity
IM687_RS02135	COG4565	transcriptional regulatory protein
IM687_RS02160	COG2204	response regulator
IM687_RS02165	COG4807	Protein conserved in bacteria
IM687_RS02190	COG5001	Diguanylate cyclase
IM687_RS02195	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IM687_RS02215	COG0003	Pfam Anion-transporting ATPase
IM687_RS02225	COG1966	Carbon starvation protein
IM687_RS02240	COG1320	monovalent cation:proton antiporter activity
IM687_RS02260	COG0651	ATP synthesis coupled electron transport
IM687_RS02265	COG0651	ATP synthesis coupled electron transport
IM687_RS02305	COG2197	response regulator
IM687_RS02330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM687_RS02335	COG0277	FAD linked oxidase domain protein
IM687_RS02340	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM687_RS02360	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IM687_RS02365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IM687_RS02375	COG0702	epimerase
IM687_RS02390	COG0494	nUDIX hydrolase
IM687_RS02405	COG0730	response to heat
IM687_RS02410	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IM687_RS02415	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IM687_RS02420	COG1192	Involved in chromosome partitioning
IM687_RS02430	COG0559	Belongs to the binding-protein-dependent transport system permease family
IM687_RS02440	COG0411	ABC transporter
IM687_RS02460	COG0739	heme binding
IM687_RS02495	COG1253	flavin adenine dinucleotide binding
IM687_RS02510	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IM687_RS02515	COG3161	chorismate lyase activity
IM687_RS02520	COG2186	Transcriptional regulator
IM687_RS02525	COG0277	FAD linked oxidase domain protein
IM687_RS02530	COG0277	FAD linked oxidase domain protein
IM687_RS02535	COG0247	lactate metabolic process
IM687_RS02540	COG3193	protein, possibly involved in utilization of glycolate and propanediol
IM687_RS02545	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IM687_RS02550	COG1620	l-lactate permease
IM687_RS02575	COG0583	DNA-binding transcription factor activity
IM687_RS02580	COG1960	acyl-CoA dehydrogenase activity
IM687_RS02590	COG0604	alcohol dehydrogenase
IM687_RS02595	COG0583	DNA-binding transcription factor activity
IM687_RS02600	COG1704	LemA family
IM687_RS02605	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IM687_RS02625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IM687_RS02645	COG2080	2 iron, 2 sulfur cluster binding
IM687_RS02665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IM687_RS02670	COG1758	RNA polymerase activity
IM687_RS02680	COG1561	YicC-like family, N-terminal region
IM687_RS02685	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IM687_RS02695	COG0708	Exodeoxyribonuclease III
IM687_RS02700	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IM687_RS02715	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IM687_RS02725	COG0756	dUTP diphosphatase activity
IM687_RS02730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IM687_RS02735	COG2003	Belongs to the UPF0758 family
IM687_RS02750	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM687_RS02770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM687_RS02775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM687_RS02785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM687_RS02790	COG0251	oxidation-reduction process
IM687_RS02810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IM687_RS02825	COG0366	Alpha amylase catalytic
IM687_RS02830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM687_RS02840	COG1454	alcohol dehydrogenase
IM687_RS02850	COG1414	Transcriptional regulator
IM687_RS02855	COG1272	protein, Hemolysin III
IM687_RS02860	COG0210	DNA helicase
IM687_RS02870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM687_RS02875	COG0606	chelatase, subunit chli
IM687_RS02885	COG0347	Belongs to the P(II) protein family
IM687_RS02890	COG0004	ammonium transporteR
IM687_RS02895	COG0004	ammonium transporteR
IM687_RS02900	COG0432	Pfam Uncharacterised protein family UPF0047
IM687_RS02915	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IM687_RS02925	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IM687_RS02940	COG1965	Belongs to the frataxin family
IM687_RS02945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IM687_RS02985	COG0165	Argininosuccinate lyase
IM687_RS02990	COG3275	phosphorelay sensor kinase activity
IM687_RS03000	COG0181	hydroxymethylbilane synthase activity
IM687_RS03020	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IM687_RS03040	COG0488	(ABC) transporter
IM687_RS03050	COG0861	Integral membrane protein TerC family
IM687_RS03055	COG1280	lysine exporter protein (LysE YggA)
IM687_RS03060	COG1671	Belongs to the UPF0178 family
IM687_RS03075	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IM687_RS03085	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IM687_RS03090	COG0248	Ppx GppA phosphatase
IM687_RS03105	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IM687_RS03120	COG0018	arginyl-trna synthetase
IM687_RS03125	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IM687_RS03130	COG0254	rRNA binding
IM687_RS03140	COG0281	malic enzyme
IM687_RS03175	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IM687_RS03180	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IM687_RS03190	COG0067	glutamate synthase
IM687_RS03190	COG0069	glutamate synthase activity
IM687_RS03190	COG0070	glutamate synthase
IM687_RS03195	COG0493	'glutamate synthase
IM687_RS03205	COG2814	Major facilitator Superfamily
IM687_RS03210	COG0583	DNA-binding transcription factor activity
IM687_RS03225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM687_RS03230	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS03270	COG2986	histidine ammonia-lyase
IM687_RS03295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM687_RS03300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM687_RS03315	COG3118	belongs to the thioredoxin family
IM687_RS03320	COG2873	o-acetylhomoserine
IM687_RS03325	COG3273	potassium ion transport
IM687_RS03325	COG0471	metal ion transport
IM687_RS03345	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IM687_RS03350	COG0732	type I restriction modification DNA specificity domain
IM687_RS03355	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IM687_RS03420	COG2944	sequence-specific DNA binding
IM687_RS03425	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
IM687_RS03440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IM687_RS03445	COG0358	DNA primase activity
IM687_RS03450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IM687_RS03455	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IM687_RS03460	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IM687_RS03475	COG0617	tRNA 3'-terminal CCA addition
IM687_RS03480	COG2719	SpoVR family
IM687_RS03485	COG2718	Belongs to the UPF0229 family
IM687_RS03490	COG2766	serine protein kinase
IM687_RS03495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM687_RS03500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IM687_RS03505	COG2967	ApaG domain
IM687_RS03510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IM687_RS03515	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IM687_RS03520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM687_RS03525	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IM687_RS03535	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IM687_RS03540	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IM687_RS03555	COG2197	response regulator
IM687_RS03560	COG3842	ATPase activity
IM687_RS03570	COG1176	ABC-type spermidine putrescine transport system, permease component I
IM687_RS03575	COG1177	transmembrane transport
IM687_RS03585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IM687_RS03590	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IM687_RS03595	COG0546	phosphoglycolate phosphatase activity
IM687_RS03605	COG0512	Glutamine amidotransferase of anthranilate synthase
IM687_RS03610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IM687_RS03615	COG0134	indole-3-glycerol-phosphate synthase activity
IM687_RS03625	COG1765	OsmC-like protein
IM687_RS03630	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IM687_RS03635	COG0537	adenosine 5'-monophosphoramidase activity
IM687_RS03640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IM687_RS03650	COG1981	membrane
IM687_RS03655	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IM687_RS03660	COG0316	Belongs to the HesB IscA family
IM687_RS03665	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IM687_RS03670	COG0739	heme binding
IM687_RS03675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IM687_RS03705	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IM687_RS03705	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IM687_RS03710	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IM687_RS03735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IM687_RS03755	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IM687_RS03760	COG0081	regulation of translation
IM687_RS03765	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IM687_RS03770	COG0222	ribosome binding
IM687_RS03775	COG0085	RNA polymerase activity
IM687_RS03780	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IM687_RS03785	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IM687_RS03790	COG0049	tRNA binding
IM687_RS03795	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IM687_RS03800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IM687_RS03805	COG0051	transcription antitermination factor activity, RNA binding
IM687_RS03810	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IM687_RS03815	COG0088	Forms part of the polypeptide exit tunnel
IM687_RS03820	COG0089	rRNA binding
IM687_RS03825	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IM687_RS03830	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IM687_RS03835	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IM687_RS03840	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IM687_RS03845	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IM687_RS03850	COG0255	Belongs to the universal ribosomal protein uL29 family
IM687_RS03855	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IM687_RS03860	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IM687_RS03865	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IM687_RS03870	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IM687_RS03875	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IM687_RS03880	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IM687_RS03885	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IM687_RS03895	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IM687_RS03900	COG1841	ribosomal large subunit assembly
IM687_RS03905	COG0200	Binds to the 23S rRNA
IM687_RS03915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IM687_RS03920	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IM687_RS03925	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IM687_RS03930	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IM687_RS03935	COG0202	RNA polymerase activity
IM687_RS03940	COG0203	ribosomal protein L17
IM687_RS03955	COG2814	Major facilitator Superfamily
IM687_RS03970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM687_RS03975	COG3047	cAMP biosynthetic process
IM687_RS03985	COG0811	peptide transport
IM687_RS03990	COG0811	peptide transport
IM687_RS03995	COG0848	biopolymer transport protein
IM687_RS04020	COG4181	ATPase activity
IM687_RS04035	COG3118	belongs to the thioredoxin family
IM687_RS04040	COG2391	methyltransferase activity
IM687_RS04045	COG0425	Belongs to the sulfur carrier protein TusA family
IM687_RS04055	COG2264	protein methyltransferase activity
IM687_RS04070	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM687_RS04070	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM687_RS04085	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IM687_RS04090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IM687_RS04100	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IM687_RS04105	COG3577	Aspartyl protease
IM687_RS04110	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM687_RS04120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM687_RS04125	COG4206	TonB-dependent receptor
IM687_RS04135	COG0420	3'-5' exonuclease activity
IM687_RS04190	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS04205	COG4829	muconolactone delta-isomerase
IM687_RS04210	COG2031	fatty acid transporter
IM687_RS04220	COG1040	competence protein
IM687_RS04225	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IM687_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS04235	COG2610	gluconate transmembrane transporter activity
IM687_RS04240	COG2031	fatty acid transporter
IM687_RS04250	COG1522	sequence-specific DNA binding
IM687_RS04265	COG0733	neurotransmitter:sodium symporter activity
IM687_RS04275	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IM687_RS04285	COG0625	glutathione transferase activity
IM687_RS04290	COG0733	neurotransmitter:sodium symporter activity
IM687_RS04310	COG4651	solute:proton antiporter activity
IM687_RS04310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM687_RS04315	COG0513	Belongs to the DEAD box helicase family
IM687_RS04340	COG0123	including yeast histone deacetylase and acetoin utilization protein
IM687_RS04350	COG1946	Acyl-CoA thioesterase
IM687_RS04360	COG2321	neutral zinc metallopeptidase
IM687_RS04385	COG2197	response regulator
IM687_RS04390	COG3850	Histidine kinase
IM687_RS04395	COG2223	nitrite transmembrane transporter activity
IM687_RS04405	COG2223	nitrite transmembrane transporter activity
IM687_RS04410	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IM687_RS04415	COG1140	nitrate reductase beta subunit
IM687_RS04420	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IM687_RS04425	COG2181	nitrate reductase activity
IM687_RS04440	COG0521	Mo-molybdopterin cofactor biosynthetic process
IM687_RS04450	COG3038	cytochrome b561
IM687_RS04480	COG1022	Amp-dependent synthetase and ligase
IM687_RS04500	COG0642	Histidine kinase
IM687_RS04510	COG3642	lipopolysaccharide core region biosynthetic process
IM687_RS04520	COG1368	sulfuric ester hydrolase activity
IM687_RS04525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM687_RS04530	COG2252	PERMEase
IM687_RS04540	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IM687_RS04540	COG3608	succinylglutamate desuccinylase aspartoacylase
IM687_RS04545	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IM687_RS04550	COG2080	2 iron, 2 sulfur cluster binding
IM687_RS04555	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IM687_RS04560	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IM687_RS04585	COG0789	Transcriptional regulator
IM687_RS04590	COG2813	Specifically methylates the guanine in position
IM687_RS04625	COG0488	(ABC) transporter
IM687_RS04630	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM687_RS04635	COG2020	methyltransferase activity
IM687_RS04655	COG2841	Protein conserved in bacteria
IM687_RS04660	COG1970	mechanosensitive ion channel activity
IM687_RS04670	COG1067	ATP-dependent peptidase activity
IM687_RS04680	COG2862	Uncharacterized protein family, UPF0114
IM687_RS04690	COG3046	protein related to deoxyribodipyrimidine photolyase
IM687_RS04700	COG0545	Peptidyl-prolyl cis-trans isomerase
IM687_RS04710	COG0142	geranyltranstransferase activity
IM687_RS04715	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IM687_RS04720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IM687_RS04725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IM687_RS04730	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IM687_RS04735	COG3045	CreA protein
IM687_RS04740	COG0268	Binds directly to 16S ribosomal RNA
IM687_RS04750	COG0196	riboflavin kinase activity
IM687_RS04755	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IM687_RS04760	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IM687_RS04765	COG1047	Peptidyl-prolyl cis-trans
IM687_RS04770	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IM687_RS04810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM687_RS04815	COG0023	Translation Initiation Factor
IM687_RS04830	COG0534	Mate efflux family protein
IM687_RS04860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM687_RS04875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IM687_RS04875	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM687_RS04880	COG1105	Belongs to the carbohydrate kinase PfkB family
IM687_RS04885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM687_RS04885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM687_RS04885	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IM687_RS04890	COG4993	Dehydrogenase
IM687_RS04895	COG2852	Protein conserved in bacteria
IM687_RS04900	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IM687_RS04905	COG0019	diaminopimelate decarboxylase activity
IM687_RS04915	COG3128	pkhd-type hydroxylase
IM687_RS04920	COG4774	siderophore transport
IM687_RS04925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IM687_RS04945	COG4771	TonB-dependent receptor
IM687_RS04960	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IM687_RS04970	COG0739	heme binding
IM687_RS04985	COG0530	calcium, potassium:sodium antiporter activity
IM687_RS05000	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IM687_RS05010	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IM687_RS05015	COG1077	Cell shape determining protein MreB Mrl
IM687_RS05020	COG1792	Involved in formation and maintenance of cell shape
IM687_RS05040	COG1530	ribonuclease E activity
IM687_RS05050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IM687_RS05055	COG0312	modulator of DNA gyrase
IM687_RS05065	COG0312	modulator of DNA gyrase
IM687_RS05070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM687_RS05075	COG1660	Displays ATPase and GTPase activities
IM687_RS05090	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IM687_RS05095	COG1137	ATPase activity
IM687_RS05110	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IM687_RS05120	COG1127	ABC transporter
IM687_RS05125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IM687_RS05130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IM687_RS05155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IM687_RS05160	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IM687_RS05170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM687_RS05175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM687_RS05185	COG0175	sulfate reduction
IM687_RS05195	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IM687_RS05195	COG2755	lipolytic protein G-D-S-L family
IM687_RS05200	COG1131	(ABC) transporter
IM687_RS05235	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IM687_RS05240	COG0237	dephospho-CoA kinase activity
IM687_RS05255	COG0667	Aldo Keto reductase
IM687_RS05260	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IM687_RS05265	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IM687_RS05270	COG0723	plastoquinol--plastocyanin reductase activity
IM687_RS05275	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IM687_RS05280	COG2857	Cytochrome c1
IM687_RS05285	COG0625	glutathione transferase activity
IM687_RS05290	COG2969	positive regulation of protein catabolic process
IM687_RS05295	COG2823	Periplasmic or secreted lipoprotein
IM687_RS05300	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IM687_RS05305	COG0792	nuclease activity
IM687_RS05330	COG0275	rRNA processing
IM687_RS05345	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IM687_RS05350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IM687_RS05355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM687_RS05360	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IM687_RS05365	COG0772	Belongs to the SEDS family
IM687_RS05370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IM687_RS05375	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IM687_RS05380	COG1181	Belongs to the D-alanine--D-alanine ligase family
IM687_RS05430	COG1285	pathogenesis
IM687_RS05455	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS05460	COG0659	secondary active sulfate transmembrane transporter activity
IM687_RS05515	COG0840	transmembrane signaling receptor activity
IM687_RS05520	COG0501	Belongs to the peptidase M48B family
IM687_RS05530	COG2119	membrane
IM687_RS05535	COG2813	Specifically methylates the guanine in position
IM687_RS05540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM687_RS05545	COG1280	lysine exporter protein (LysE YggA)
IM687_RS05550	COG0318	PFAM AMP-dependent synthetase and ligase
IM687_RS05560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM687_RS05565	COG2885	chlorophyll binding
IM687_RS05570	COG0784	Response regulator, receiver
IM687_RS05570	COG2205	protein histidine kinase activity
IM687_RS05580	COG0204	Acyl-transferase
IM687_RS05590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IM687_RS05600	COG0386	Belongs to the glutathione peroxidase family
IM687_RS05605	COG1309	transcriptional regulator
IM687_RS05615	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
IM687_RS05630	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IM687_RS05635	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS05675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM687_RS05680	COG0693	protein deglycase activity
IM687_RS05685	COG4628	conserved protein (DUF2132)
IM687_RS05705	COG0469	pyruvate kinase activity
IM687_RS05730	COG0714	Associated with various cellular activities
IM687_RS05755	COG2925	Exonuclease
IM687_RS05765	COG0788	formyltetrahydrofolate deformylase activity
IM687_RS05775	COG0433	COG0433 Predicted ATPase
IM687_RS05790	COG3022	response to hydroperoxide
IM687_RS05800	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IM687_RS05805	COG0315	cyclic pyranopterin monophosphate synthase activity
IM687_RS05810	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IM687_RS05830	COG0400	carboxylic ester hydrolase activity
IM687_RS05835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM687_RS05840	COG4597	amino acid ABC transporter
IM687_RS05845	COG0765	amino acid transport
IM687_RS05850	COG1126	abc transporter atp-binding protein
IM687_RS05855	COG0047	phosphoribosylformylglycinamidine synthase activity
IM687_RS05855	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IM687_RS05925	COG3034	peptidoglycan biosynthetic process
IM687_RS05950	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IM687_RS05955	COG4536	flavin adenine dinucleotide binding
IM687_RS05960	COG4137	Cytochrome C assembly protein
IM687_RS05965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IM687_RS05970	COG0228	four-way junction DNA binding
IM687_RS05975	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IM687_RS05980	COG0336	Belongs to the RNA methyltransferase TrmD family
IM687_RS05985	COG0335	large ribosomal subunit rRNA binding
IM687_RS06000	COG3791	Glutathione-dependent formaldehyde-activating
IM687_RS06015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM687_RS06020	COG0418	dihydroorotase activity
IM687_RS06030	COG0137	argininosuccinate synthase activity
IM687_RS06035	COG0346	lactoylglutathione lyase activity
IM687_RS06045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IM687_RS06055	COG4659	FMN binding
IM687_RS06060	COG4658	electron transport chain
IM687_RS06070	COG2878	Part of a membrane complex involved in electron transport
IM687_RS06075	COG4657	Part of a membrane complex involved in electron transport
IM687_RS06090	COG1024	Enoyl-CoA hydratase
IM687_RS06100	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IM687_RS06115	COG0354	folic acid binding
IM687_RS06155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM687_RS06160	COG0481	GTPase activity
IM687_RS06175	COG0571	ribonuclease III activity
IM687_RS06185	COG1381	Involved in DNA repair and RecF pathway recombination
IM687_RS06190	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IM687_RS06200	COG0583	DNA-binding transcription factor activity
IM687_RS06210	COG0500	methyltransferase
IM687_RS06215	COG2226	methyltransferase
IM687_RS06225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IM687_RS06240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM687_RS06255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM687_RS06265	COG0583	DNA-binding transcription factor activity
IM687_RS06270	COG3485	protocatechuate 3,4-dioxygenase
IM687_RS06275	COG3485	protocatechuate 3,4-dioxygenase
IM687_RS06280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IM687_RS06285	COG0679	Auxin Efflux Carrier
IM687_RS06290	COG1414	Transcriptional regulator
IM687_RS06295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IM687_RS06300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IM687_RS06315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IM687_RS06320	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM687_RS06340	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM687_RS06340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM687_RS06345	COG0489	protein tyrosine kinase activity
IM687_RS06350	COG1278	Cold shock
IM687_RS06355	COG0717	Belongs to the dCTP deaminase family
IM687_RS06360	COG3005	denitrification pathway
IM687_RS06370	COG0243	molybdopterin cofactor binding
IM687_RS06380	COG4459	periplasmic nitrate reductase
IM687_RS06385	COG2814	Major facilitator Superfamily
IM687_RS06410	COG0037	tRNA processing
IM687_RS06415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IM687_RS06420	COG2818	Glycosylase
IM687_RS06445	COG1294	oxidase, subunit
IM687_RS06450	COG4890	Cyd operon protein YbgT
IM687_RS06465	COG0791	NLP P60 protein
IM687_RS06470	COG0791	NLP P60 protein
IM687_RS06485	COG4206	TonB-dependent receptor
IM687_RS06500	COG1797	cobyrinic acid a,c-diamide synthase activity
IM687_RS06505	COG0778	Nitroreductase
IM687_RS06515	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IM687_RS06525	COG1492	cobalamin metabolic process
IM687_RS06535	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IM687_RS06545	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IM687_RS06555	COG0251	oxidation-reduction process
IM687_RS06585	COG2067	long-chain fatty acid transport protein
IM687_RS06600	COG3100	YcgL domain-containing protein
IM687_RS06610	COG2983	Belongs to the UPF0260 family
IM687_RS06625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IM687_RS06630	COG0527	aspartate kinase activity
IM687_RS06635	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IM687_RS06660	COG2239	Acts as a magnesium transporter
IM687_RS06665	COG3630	sodium ion export across plasma membrane
IM687_RS06670	COG0511	ligase activity, forming carbon-carbon bonds
IM687_RS06670	COG5016	pyruvate
IM687_RS06675	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
IM687_RS06700	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IM687_RS06720	COG0784	Response regulator, receiver
IM687_RS06720	COG0835	chemotaxis
IM687_RS06725	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IM687_RS06730	COG1815	bacterial-type flagellum-dependent cell motility
IM687_RS06750	COG4787	bacterial-type flagellum-dependent cell motility
IM687_RS06755	COG4786	Flagellar basal body rod
IM687_RS06760	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IM687_RS06765	COG1706	bacterial-type flagellum-dependent cell motility
IM687_RS06775	COG1256	bacterial-type flagellum assembly
IM687_RS06785	COG1555	photosystem II stabilization
IM687_RS06810	COG2200	EAL domain
IM687_RS06825	COG1362	aminopeptidase activity
IM687_RS06835	COG0564	pseudouridine synthase activity
IM687_RS06840	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IM687_RS06845	COG2894	cell division
IM687_RS06850	COG0850	regulation of cytokinetic process
IM687_RS06855	COG1560	Kdo2-lipid A biosynthetic process
IM687_RS06865	COG2853	Lipoprotein
IM687_RS06880	COG3162	membrane
IM687_RS06885	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM687_RS06905	COG3089	Belongs to the UPF0270 family
IM687_RS06915	COG1363	Peptidase, m42
IM687_RS06920	COG0189	ligase activity
IM687_RS06920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IM687_RS06925	COG0367	asparagine synthase
IM687_RS06935	COG1404	Belongs to the peptidase S8 family
IM687_RS06935	COG4935	Belongs to the peptidase S8 family
IM687_RS06945	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM687_RS06955	COG4221	oxidoreductase activity
IM687_RS06965	COG1201	RNA secondary structure unwinding
IM687_RS07005	COG2133	pyrroloquinoline quinone binding
IM687_RS07010	COG4993	Dehydrogenase
IM687_RS07015	COG2996	Protein conserved in bacteria
IM687_RS07030	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IM687_RS07095	COG2130	NADP-dependent
IM687_RS07105	COG3135	benzoate transporter
IM687_RS07110	COG1677	Flagellar hook-basal body complex protein FliE
IM687_RS07145	COG0745	RESPONSE REGULATOR receiver
IM687_RS07185	COG1987	bacterial-type flagellum assembly
IM687_RS07200	COG2032	superoxide dismutase activity
IM687_RS07230	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IM687_RS07235	COG0643	Histidine kinase
IM687_RS07235	COG0784	Response regulator, receiver
IM687_RS07235	COG2198	Histidine kinase
IM687_RS07240	COG2201	protein-glutamate methylesterase activity
IM687_RS07245	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IM687_RS07250	COG1360	Flagellar Motor Protein
IM687_RS07255	COG1192	Involved in chromosome partitioning
IM687_RS07265	COG0835	chemotaxis
IM687_RS07280	COG2257	FlhB HrpN YscU SpaS Family
IM687_RS07310	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IM687_RS07360	COG0500	methyltransferase
IM687_RS07370	COG0501	Belongs to the peptidase M48B family
IM687_RS07380	COG0436	Aminotransferase
IM687_RS07385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM687_RS07390	COG0386	Belongs to the glutathione peroxidase family
IM687_RS07425	COG0640	Transcriptional regulator
IM687_RS07455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM687_RS07455	COG3453	Protein conserved in bacteria
IM687_RS07465	COG1136	(ABC) transporter
IM687_RS07470	COG4591	ABC-type transport system involved in lipoprotein release permease component
IM687_RS07495	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
IM687_RS07510	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IM687_RS07515	COG0471	metal ion transport
IM687_RS07520	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IM687_RS07525	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IM687_RS07530	COG0840	transmembrane signaling receptor activity
IM687_RS07540	COG0776	regulation of translation
IM687_RS07550	COG2977	Belongs to the P-Pant transferase superfamily
IM687_RS07560	COG0183	Belongs to the thiolase family
IM687_RS07600	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IM687_RS07605	COG3206	protein involved in exopolysaccharide biosynthesis
IM687_RS07605	COG0489	protein tyrosine kinase activity
IM687_RS07610	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IM687_RS07615	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IM687_RS07625	COG3437	response regulator, receiver
IM687_RS07630	COG3217	Mosc domain protein beta barrel domain protein
IM687_RS07630	COG0633	Ferredoxin
IM687_RS07635	COG0741	lytic transglycosylase activity
IM687_RS07640	COG0488	(ABC) transporter
IM687_RS07650	COG0589	response to stress
IM687_RS07660	COG0121	glutamine amidotransferase
IM687_RS07680	COG0542	response to heat
IM687_RS07690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM687_RS07700	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
IM687_RS07715	COG2832	Protein of unknown function (DUF454)
IM687_RS07725	COG0514	ATP-dependent DNA helicase (RecQ)
IM687_RS07735	COG1752	Esterase of the alpha-beta hydrolase superfamily
IM687_RS07770	COG2354	Protein conserved in bacteria
IM687_RS07775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM687_RS07780	COG0727	PFAM Uncharacterised protein family (UPF0153)
IM687_RS07785	COG0778	Nitroreductase
IM687_RS07800	COG0745	RESPONSE REGULATOR receiver
IM687_RS07810	COG2350	Protein conserved in bacteria
IM687_RS07815	COG0613	PHP domain protein
IM687_RS07820	COG0009	L-threonylcarbamoyladenylate synthase
IM687_RS07825	COG0180	Tryptophanyl-tRNA synthetase
IM687_RS07835	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IM687_RS07860	COG1653	transport
IM687_RS07865	COG1175	transmembrane transport
IM687_RS07870	COG0395	ABC-type sugar transport system, permease component
IM687_RS07875	COG3842	ATPase activity
IM687_RS07880	COG4580	involved in the transport of maltose and maltodextrins
IM687_RS07895	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IM687_RS07905	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IM687_RS07930	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IM687_RS07945	COG0730	response to heat
IM687_RS07960	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IM687_RS07965	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IM687_RS07985	COG0308	aminopeptidase N
IM687_RS08005	COG0243	molybdopterin cofactor binding
IM687_RS08010	COG2146	nitrite reductase [NAD(P)H] activity
IM687_RS08015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM687_RS08025	COG2815	serine threonine protein kinase
IM687_RS08025	COG0515	serine threonine protein kinase
IM687_RS08030	COG2223	nitrite transmembrane transporter activity
IM687_RS08050	COG3707	response regulator
IM687_RS08055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM687_RS08065	COG2304	oxidoreductase activity
IM687_RS08085	COG0714	Associated with various cellular activities
IM687_RS08105	COG0167	dihydroorotate dehydrogenase activity
IM687_RS08110	COG3130	regulation of translation
IM687_RS08115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IM687_RS08115	COG0116	Belongs to the methyltransferase superfamily
IM687_RS08120	COG2027	D-alanyl-D-alanine carboxypeptidase
IM687_RS08125	COG3171	Protein conserved in bacteria
IM687_RS08200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM687_RS08210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IM687_RS08220	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IM687_RS08225	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IM687_RS08230	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IM687_RS08235	COG0072	phenylalanine-tRNA ligase activity
IM687_RS08240	COG0776	regulation of translation
IM687_RS08255	COG0745	RESPONSE REGULATOR receiver
IM687_RS08270	COG1126	abc transporter atp-binding protein
IM687_RS08275	COG0765	amino acid transport
IM687_RS08280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM687_RS08300	COG0587	DNA-directed DNA polymerase activity
IM687_RS08315	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IM687_RS08325	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IM687_RS08330	COG0077	Prephenate dehydratase
IM687_RS08330	COG1605	Chorismate mutase
IM687_RS08340	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IM687_RS08345	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IM687_RS08360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM687_RS08365	COG0625	glutathione transferase activity
IM687_RS08375	COG2840	Smr protein MutS2
IM687_RS08400	COG0800	Aldolase
IM687_RS08410	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS08415	COG0546	phosphoglycolate phosphatase activity
IM687_RS08420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM687_RS08425	COG0402	S-adenosylhomocysteine deaminase activity
IM687_RS08455	COG0784	Response regulator, receiver
IM687_RS08455	COG4191	Histidine kinase
IM687_RS08465	COG0114	fumarate hydratase activity
IM687_RS08475	COG0271	Belongs to the BolA IbaG family
IM687_RS08480	COG1054	Belongs to the UPF0176 family
IM687_RS08495	COG0840	transmembrane signaling receptor activity
IM687_RS08520	COG0583	DNA-binding transcription factor activity
IM687_RS08525	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
IM687_RS08530	COG1960	acyl-CoA dehydrogenase activity
IM687_RS08540	COG2079	MmgE PrpD family protein
IM687_RS08570	COG3755	Protein conserved in bacteria
IM687_RS08575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM687_RS08580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM687_RS08585	COG0583	DNA-binding transcription factor activity
IM687_RS08600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM687_RS08610	COG1770	oligopeptidase
IM687_RS08615	COG1024	Enoyl-CoA hydratase
IM687_RS08615	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM687_RS08620	COG0183	Belongs to the thiolase family
IM687_RS08685	COG0653	protein targeting
IM687_RS08705	COG0133	tryptophan synthase activity
IM687_RS08710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM687_RS08715	COG1012	belongs to the aldehyde dehydrogenase family
IM687_RS08720	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IM687_RS08725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IM687_RS08750	COG0297	glycogen (starch) synthase activity
IM687_RS08780	COG0250	Participates in transcription elongation, termination and antitermination
IM687_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS08855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IM687_RS08860	COG0066	3-isopropylmalate dehydratase activity
IM687_RS08890	COG0135	phosphoribosylanthranilate isomerase activity
IM687_RS08895	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IM687_RS08900	COG0285	dihydrofolate synthase activity
IM687_RS08905	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IM687_RS08910	COG1286	toxin biosynthetic process
IM687_RS08970	COG0515	serine threonine protein kinase
IM687_RS08970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM687_RS08975	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM687_RS08980	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM687_RS08990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IM687_RS09000	COG2207	Transcriptional regulator
IM687_RS09005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM687_RS09015	COG0745	RESPONSE REGULATOR receiver
IM687_RS09020	COG2205	protein histidine kinase activity
IM687_RS09030	COG0668	transmembrane transport
IM687_RS09075	COG2988	succinylglutamate desuccinylase activity
IM687_RS09080	COG1131	(ABC) transporter
IM687_RS09085	COG0842	Transport permease protein
IM687_RS09090	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IM687_RS09090	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IM687_RS09100	COG2853	Lipoprotein
IM687_RS09110	COG0745	RESPONSE REGULATOR receiver
IM687_RS09120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IM687_RS09140	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IM687_RS09175	COG2814	Major facilitator Superfamily
IM687_RS09180	COG4948	Mandelate Racemase Muconate Lactonizing
IM687_RS09185	COG4829	muconolactone delta-isomerase
IM687_RS09190	COG3485	protocatechuate 3,4-dioxygenase
IM687_RS09195	COG3135	benzoate transporter
IM687_RS09230	COG0720	synthase
IM687_RS09235	COG2056	Na+-H+ antiporter family
IM687_RS09240	COG0628	permease
IM687_RS09265	COG2153	protein acetylation
IM687_RS09270	COG2850	peptidyl-arginine hydroxylation
IM687_RS09280	COG2915	High frequency lysogenization protein hflD homolog
IM687_RS09285	COG0482	sulfurtransferase activity
IM687_RS09310	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IM687_RS09315	COG0542	response to heat
IM687_RS09320	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IM687_RS09325	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IM687_RS09330	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IM687_RS09335	COG0492	ferredoxin-NADP+ reductase activity
IM687_RS09345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IM687_RS09350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IM687_RS09355	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IM687_RS09360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IM687_RS09365	COG1648	precorrin-2 dehydrogenase activity
IM687_RS09365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IM687_RS09385	COG1131	(ABC) transporter
IM687_RS09405	COG0840	transmembrane signaling receptor activity
IM687_RS09465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM687_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS09495	COG4172	Belongs to the ABC transporter superfamily
IM687_RS09500	COG4239	(ABC) transporter, permease
IM687_RS09505	COG4174	ABC transporter (Permease)
IM687_RS09515	COG4166	transmembrane transport
IM687_RS09525	COG1388	LysM domain
IM687_RS09525	COG0741	lytic transglycosylase activity
IM687_RS09530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM687_RS09540	COG0328	RNA-DNA hybrid ribonuclease activity
IM687_RS09545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM687_RS09555	COG1024	Enoyl-CoA hydratase
IM687_RS09565	COG2816	NAD+ diphosphatase activity
IM687_RS09580	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS09600	COG0616	signal peptide processing
IM687_RS09605	COG0604	alcohol dehydrogenase
IM687_RS09625	COG0071	Belongs to the small heat shock protein (HSP20) family
IM687_RS09640	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IM687_RS09645	COG2223	nitrite transmembrane transporter activity
IM687_RS09670	COG2755	lipolytic protein G-D-S-L family
IM687_RS09670	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IM687_RS09690	COG0316	Belongs to the HesB IscA family
IM687_RS09690	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IM687_RS09695	COG2201	protein-glutamate methylesterase activity
IM687_RS09700	COG3706	GGDEF domain
IM687_RS09715	COG2323	membrane
IM687_RS09730	COG0840	transmembrane signaling receptor activity
IM687_RS09735	COG1968	undecaprenyl-diphosphatase activity
IM687_RS09740	COG0488	(ABC) transporter
IM687_RS09765	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IM687_RS09770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM687_RS09775	COG3265	gluconokinase activity
IM687_RS09780	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IM687_RS09785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IM687_RS09790	COG1609	Transcriptional regulator
IM687_RS09805	COG1070	Carbohydrate kinase
IM687_RS09825	COG1175	transmembrane transport
IM687_RS09860	COG0729	surface antigen
IM687_RS09865	COG2911	Protein conserved in bacteria
IM687_RS09870	COG1115	amino acid carrier protein
IM687_RS09885	COG0728	peptidoglycan biosynthetic process
IM687_RS09895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM687_RS09945	COG0604	alcohol dehydrogenase
IM687_RS09945	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS09945	COG3321	synthase
IM687_RS09950	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS09970	COG0437	4 iron, 4 sulfur cluster binding
IM687_RS09975	COG2864	formate dehydrogenase
IM687_RS09995	COG0366	Alpha amylase catalytic
IM687_RS10000	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IM687_RS10005	COG0392	lysyltransferase activity
IM687_RS10010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM687_RS10015	COG3568	Endonuclease Exonuclease Phosphatase
IM687_RS10030	COG0583	DNA-binding transcription factor activity
IM687_RS10035	COG3384	dioxygenase
IM687_RS10045	COG0739	heme binding
IM687_RS10070	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IM687_RS10075	COG0297	glycogen (starch) synthase activity
IM687_RS10080	COG1058	Belongs to the CinA family
IM687_RS10080	COG1546	Belongs to the CinA family
IM687_RS10085	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IM687_RS10085	COG3264	Mechanosensitive ion channel
IM687_RS10090	COG3685	Protein conserved in bacteria
IM687_RS10115	COG0028	Belongs to the TPP enzyme family
IM687_RS10120	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS10125	COG0723	plastoquinol--plastocyanin reductase activity
IM687_RS10140	COG0583	DNA-binding transcription factor activity
IM687_RS10150	COG1566	PFAM secretion protein HlyD family protein
IM687_RS10175	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IM687_RS10225	COG5642	Protein of unknown function (DUF2384)
IM687_RS10250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM687_RS10255	COG1742	UPF0060 membrane protein
IM687_RS10265	COG0431	NADPH-dependent FMN reductase
IM687_RS10270	COG0640	Transcriptional regulator
IM687_RS10275	COG2072	flavoprotein involved in K transport
IM687_RS10280	COG0798	PFAM Bile acid sodium symporter
IM687_RS10335	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM687_RS10340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM687_RS10355	COG5002	protein histidine kinase activity
IM687_RS10370	COG0535	radical SAM domain protein
IM687_RS10380	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
IM687_RS10385	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IM687_RS10425	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IM687_RS10430	COG0167	dihydroorotate dehydrogenase activity
IM687_RS10435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM687_RS10445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IM687_RS10450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IM687_RS10460	COG0544	peptidyl-prolyl cis-trans isomerase activity
IM687_RS10470	COG2186	Transcriptional regulator
IM687_RS10490	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IM687_RS10495	COG0215	cysteine-tRNA ligase activity
IM687_RS10500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IM687_RS10505	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IM687_RS10510	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM687_RS10545	COG0668	transmembrane transport
IM687_RS10560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IM687_RS10570	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IM687_RS10585	COG0372	Belongs to the citrate synthase family
IM687_RS10595	COG1802	Transcriptional regulator
IM687_RS10620	COG0560	Phosphoserine phosphatase
IM687_RS10635	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IM687_RS10640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IM687_RS10670	COG4181	ATPase activity
IM687_RS10675	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IM687_RS10695	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IM687_RS10700	COG0084	hydrolase, TatD family'
IM687_RS10715	COG3842	ATPase activity
IM687_RS10720	COG3665	Urea carboxylase-associated protein
IM687_RS10730	COG0439	Biotin carboxylase
IM687_RS10745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM687_RS10755	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS10775	COG1335	isochorismatase
IM687_RS10785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM687_RS10790	COG1116	anion transmembrane transporter activity
IM687_RS10795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IM687_RS10800	COG0174	glutamine synthetase
IM687_RS10850	COG2920	part of a sulfur-relay system
IM687_RS10855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IM687_RS10860	COG0435	Glutathione S-transferase
IM687_RS10865	COG0784	Response regulator, receiver
IM687_RS10865	COG2205	protein histidine kinase activity
IM687_RS10880	COG1025	Belongs to the peptidase M16 family
IM687_RS10885	COG0789	Transcriptional regulator
IM687_RS10895	COG0302	gtp cyclohydrolase
IM687_RS10900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IM687_RS10915	COG1366	Belongs to the anti-sigma-factor antagonist family
IM687_RS10925	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IM687_RS10930	COG1090	epimerase
IM687_RS10935	COG3272	Protein of unknown function (DUF1722)
IM687_RS10940	COG0789	Transcriptional regulator
IM687_RS10945	COG0415	Belongs to the DNA photolyase family
IM687_RS10955	COG4221	oxidoreductase activity
IM687_RS10970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IM687_RS10980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IM687_RS10990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM687_RS10990	COG2146	nitrite reductase [NAD(P)H] activity
IM687_RS10995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM687_RS10995	COG2146	nitrite reductase [NAD(P)H] activity
IM687_RS11005	COG0515	serine threonine protein kinase
IM687_RS11010	COG0210	DNA helicase
IM687_RS11050	COG3447	MASE1 domain protein
IM687_RS11050	COG5001	Diguanylate cyclase
IM687_RS11050	COG5002	protein histidine kinase activity
IM687_RS11065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IM687_RS11085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM687_RS11090	COG0784	Response regulator, receiver
IM687_RS11090	COG4191	Histidine kinase
IM687_RS11095	COG4991	sh3 domain protein
IM687_RS11110	COG2207	Transcriptional regulator
IM687_RS11125	COG0058	SHG alpha-glucan phosphorylase activity
IM687_RS11130	COG0745	RESPONSE REGULATOR receiver
IM687_RS11135	COG2205	protein histidine kinase activity
IM687_RS11150	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IM687_RS11185	COG1024	Enoyl-CoA hydratase
IM687_RS11190	COG1960	acyl-CoA dehydrogenase activity
IM687_RS11200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IM687_RS11205	COG0318	PFAM AMP-dependent synthetase and ligase
IM687_RS11210	COG1960	acyl-CoA dehydrogenase activity
IM687_RS11215	COG0183	Belongs to the thiolase family
IM687_RS11230	COG1238	metal cluster binding
IM687_RS11255	COG0714	Associated with various cellular activities
IM687_RS11265	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
IM687_RS11270	COG0709	Synthesizes selenophosphate from selenide and ATP
IM687_RS11280	COG0628	permease
IM687_RS11315	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IM687_RS11320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IM687_RS11330	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IM687_RS11360	COG0326	Molecular chaperone. Has ATPase activity
IM687_RS11395	COG0045	succinate-CoA ligase (ADP-forming) activity
IM687_RS11415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IM687_RS11420	COG1053	succinate dehydrogenase
IM687_RS11425	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IM687_RS11430	COG2009	succinate dehydrogenase
IM687_RS11445	COG3123	guanosine phosphorylase activity
IM687_RS11460	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IM687_RS11475	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IM687_RS11480	COG3115	cell septum assembly
IM687_RS11490	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IM687_RS11495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM687_RS11510	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IM687_RS11510	COG2010	Cytochrome c
IM687_RS11515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM687_RS11535	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
IM687_RS11545	COG0840	transmembrane signaling receptor activity
IM687_RS11555	COG3278	Belongs to the heme-copper respiratory oxidase family
IM687_RS11565	COG2010	Cytochrome c
IM687_RS11570	COG3278	Belongs to the heme-copper respiratory oxidase family
IM687_RS11585	COG2010	Cytochrome c
IM687_RS11615	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IM687_RS11625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM687_RS11630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IM687_RS11645	COG0573	inorganic phosphate transmembrane transporter activity
IM687_RS11660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IM687_RS11665	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IM687_RS11670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IM687_RS11675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM687_RS11705	COG1902	pentaerythritol trinitrate reductase activity
IM687_RS11705	COG0446	pyridine nucleotide-disulphide oxidoreductase
IM687_RS11725	COG1294	oxidase, subunit
IM687_RS11730	COG1271	oxidase subunit
IM687_RS11760	COG0655	NAD(P)H dehydrogenase (quinone) activity
IM687_RS11785	COG0477	Major facilitator Superfamily
IM687_RS11810	COG0583	DNA-binding transcription factor activity
IM687_RS11815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IM687_RS11825	COG2226	methyltransferase
IM687_RS11830	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
IM687_RS11855	COG0583	DNA-binding transcription factor activity
IM687_RS11880	COG0789	Transcriptional regulator
IM687_RS11885	COG2188	Transcriptional regulator
IM687_RS11900	COG0840	transmembrane signaling receptor activity
IM687_RS11930	COG0826	peptidase U32
IM687_RS11950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM687_RS11975	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IM687_RS11990	COG1283	sodium-dependent phosphate transmembrane transporter activity
IM687_RS12000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IM687_RS12005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM687_RS12050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM687_RS12055	COG0004	ammonium transporteR
IM687_RS12070	COG2258	MOSC domain
IM687_RS12080	COG0217	transcriptional regulatory protein
IM687_RS12090	COG0589	response to stress
IM687_RS12145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IM687_RS12150	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IM687_RS12155	COG0585	pseudouridine synthase activity
IM687_RS12160	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IM687_RS12170	COG1902	pentaerythritol trinitrate reductase activity
IM687_RS12175	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IM687_RS12185	COG0583	DNA-binding transcription factor activity
IM687_RS12200	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IM687_RS12215	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IM687_RS12220	COG0504	CTP synthase activity
IM687_RS12225	COG0037	tRNA processing
IM687_RS12230	COG0825	malonyl-CoA metabolic process
IM687_RS12240	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IM687_RS12245	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM687_RS12250	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM687_RS12255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IM687_RS12260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IM687_RS12270	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM687_RS12280	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IM687_RS12290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IM687_RS12295	COG0233	cytoplasmic translational termination
IM687_RS12300	COG0528	UMP kinase activity
IM687_RS12305	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IM687_RS12310	COG0052	Belongs to the universal ribosomal protein uS2 family
IM687_RS12315	COG0024	Methionine aminopeptidase
IM687_RS12320	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IM687_RS12325	COG1320	monovalent cation:proton antiporter activity
IM687_RS12330	COG2212	antiporter activity
IM687_RS12335	COG1863	multisubunit Na H antiporter MnhE subunit
IM687_RS12340	COG0651	ATP synthesis coupled electron transport
IM687_RS12345	COG1006	Multisubunit Na H antiporter MnhC subunit
IM687_RS12350	COG2111	Na H antiporter
IM687_RS12350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IM687_RS12365	COG0259	pyridoxamine-phosphate oxidase activity
IM687_RS12375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM687_RS12380	COG1199	ATP-dependent helicase activity
IM687_RS12400	COG3012	SEC-C Motif Domain Protein
IM687_RS12410	COG0583	DNA-binding transcription factor activity
IM687_RS12420	COG0697	spore germination
IM687_RS12425	COG3148	PFAM DTW domain containing protein
IM687_RS12435	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IM687_RS12440	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IM687_RS12450	COG2137	regulation of response to DNA damage stimulus
IM687_RS12455	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IM687_RS12460	COG1546	Belongs to the CinA family
IM687_RS12470	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IM687_RS12475	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IM687_RS12495	COG0438	transferase activity, transferring glycosyl groups
IM687_RS12500	COG1295	ribonuclease BN
IM687_RS12525	COG3300	MHYT domain
IM687_RS12525	COG5001	Diguanylate cyclase
IM687_RS12535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM687_RS12595	COG1113	amino acid transport
IM687_RS12600	COG0084	hydrolase, TatD family'
IM687_RS12615	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IM687_RS12620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IM687_RS12630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM687_RS12635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM687_RS12650	COG0416	fatty acid biosynthetic process
IM687_RS12655	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IM687_RS12665	COG0424	maF-like protein
IM687_RS12670	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IM687_RS12670	COG0616	signal peptide processing
IM687_RS12685	COG1530	ribonuclease E activity
IM687_RS12690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IM687_RS12695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IM687_RS12700	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IM687_RS12705	COG2835	tetraacyldisaccharide 4'-kinase activity
IM687_RS12710	COG1663	tetraacyldisaccharide 4'-kinase activity
IM687_RS12720	COG0811	peptide transport
IM687_RS12725	COG0658	competence protein
IM687_RS12725	COG2333	competence protein COMEC
IM687_RS12735	COG4591	ABC-type transport system involved in lipoprotein release permease component
IM687_RS12740	COG1136	(ABC) transporter
IM687_RS12745	COG4591	ABC-type transport system involved in lipoprotein release permease component
IM687_RS12760	COG0584	glycerophosphoryl diester phosphodiesterase
IM687_RS12765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM687_RS12775	COG1477	protein flavinylation
IM687_RS12785	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IM687_RS12800	COG1805	sodium ion transport
IM687_RS12815	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IM687_RS12825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM687_RS12840	COG1793	dna ligase
IM687_RS12845	COG1201	RNA secondary structure unwinding
IM687_RS12875	COG3956	TIGRFAM MazG family protein
IM687_RS12880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IM687_RS12885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM687_RS12900	COG2860	membrane
IM687_RS12905	COG0784	Response regulator, receiver
IM687_RS12905	COG5002	protein histidine kinase activity
IM687_RS12905	COG2205	protein histidine kinase activity
IM687_RS12910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM687_RS12910	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IM687_RS12930	COG0583	DNA-binding transcription factor activity
IM687_RS12945	COG0513	Belongs to the DEAD box helicase family
IM687_RS12990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IM687_RS12995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM687_RS13000	COG2226	methyltransferase
IM687_RS13025	COG1131	(ABC) transporter
IM687_RS13055	COG2937	Belongs to the GPAT DAPAT family
IM687_RS13060	COG0456	acetyltransferase
IM687_RS13075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM687_RS13100	COG2132	Multicopper oxidase
IM687_RS13125	COG0456	acetyltransferase
IM687_RS13130	COG0655	NAD(P)H dehydrogenase (quinone) activity
IM687_RS13155	COG1472	Belongs to the glycosyl hydrolase 3 family
IM687_RS13165	COG1346	cytolysis
IM687_RS13170	COG1380	Effector of murein hydrolase LrgA
IM687_RS13175	COG0348	domain, Protein
IM687_RS13180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM687_RS13200	COG1309	transcriptional regulator
IM687_RS13205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM687_RS13210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM687_RS13220	COG0742	ribosomal rna small subunit methyltransferase
IM687_RS13245	COG0563	adenylate kinase activity
IM687_RS13250	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IM687_RS13290	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IM687_RS13305	COG1902	pentaerythritol trinitrate reductase activity
IM687_RS13310	COG0243	molybdopterin cofactor binding
IM687_RS13315	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IM687_RS13325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IM687_RS13330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IM687_RS13335	COG1984	allophanate hydrolase subunit 2
IM687_RS13340	COG4336	lyase activity
IM687_RS13345	COG1914	H( )-stimulated, divalent metal cation uptake system
IM687_RS13370	COG0545	Peptidyl-prolyl cis-trans isomerase
IM687_RS13385	COG2974	May be involved in recombination
IM687_RS13390	COG2814	Major facilitator Superfamily
IM687_RS13410	COG2205	protein histidine kinase activity
IM687_RS13415	COG3174	membrane
IM687_RS13450	COG0417	DNA replication proofreading
IM687_RS13460	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IM687_RS13470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM687_RS13480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IM687_RS13490	COG0425	Belongs to the sulfur carrier protein TusA family
IM687_RS13500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IM687_RS13505	COG0427	acetyl-CoA hydrolase
IM687_RS13515	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IM687_RS13520	COG0602	queuosine metabolic process
IM687_RS13525	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IM687_RS13530	COG2885	chlorophyll binding
IM687_RS13535	COG0823	Involved in the tonB-independent uptake of proteins
IM687_RS13555	COG0824	Thioesterase
IM687_RS13560	COG2255	four-way junction helicase activity
IM687_RS13565	COG0632	four-way junction helicase activity
IM687_RS13570	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IM687_RS13580	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IM687_RS13585	COG0783	Belongs to the Dps family
IM687_RS13595	COG2900	Belongs to the SlyX family
IM687_RS13610	COG0442	prolyl-tRNA aminoacylation
IM687_RS13625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM687_RS13640	COG1295	ribonuclease BN
IM687_RS13660	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IM687_RS13665	COG0628	permease
IM687_RS13675	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IM687_RS13680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IM687_RS13695	COG0436	Aminotransferase
IM687_RS13770	COG3617	BRO family, N-terminal domain
IM687_RS13875	COG3728	DNA packaging
IM687_RS14015	COG3723	Recombinational DNA repair protein, rece pathway
IM687_RS14030	COG0629	single-stranded DNA binding
IM687_RS14080	COG0582	viral genome integration into host DNA
IM687_RS14085	COG1393	Belongs to the ArsC family
IM687_RS14090	COG2171	N-acyltransferase activity
IM687_RS14095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM687_RS14100	COG2166	iron-sulfur cluster assembly
IM687_RS14110	COG3258	Cytochrome c
IM687_RS14115	COG2863	cytochrome
IM687_RS14125	COG3530	Putative quorum-sensing-regulated virulence factor
IM687_RS14135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IM687_RS14145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IM687_RS14150	COG3932	Exopolysaccharide synthesis, ExoD
IM687_RS14155	COG0583	DNA-binding transcription factor activity
IM687_RS14160	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS14170	COG1280	lysine exporter protein (LysE YggA)
IM687_RS14190	COG1462	curli production assembly transport component CsgG
IM687_RS14210	COG1309	transcriptional regulator
IM687_RS14215	COG0583	DNA-binding transcription factor activity
IM687_RS14220	COG0189	ligase activity
IM687_RS14220	COG4067	protein conserved in archaea
IM687_RS14225	COG0116	Belongs to the methyltransferase superfamily
IM687_RS14225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IM687_RS14230	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IM687_RS14245	COG3321	synthase
IM687_RS14245	COG0604	alcohol dehydrogenase
IM687_RS14255	COG3284	Transcriptional regulator
IM687_RS14270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IM687_RS14275	COG1063	alcohol dehydrogenase
IM687_RS14280	COG0022	dehydrogenase e1 component
IM687_RS14285	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM687_RS14290	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM687_RS14320	COG0583	DNA-binding transcription factor activity
IM687_RS14325	COG0625	glutathione transferase activity
IM687_RS14355	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM687_RS14430	COG2132	Multicopper oxidase
IM687_RS14450	COG2217	Heavy metal translocating P-type atpase
IM687_RS14510	COG0469	pyruvate kinase activity
IM687_RS14525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM687_RS14530	COG0765	amino acid transport
IM687_RS14535	COG0765	amino acid transport
IM687_RS14540	COG1126	abc transporter atp-binding protein
IM687_RS14545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM687_RS14550	COG3665	Urea carboxylase-associated protein
IM687_RS14560	COG1280	lysine exporter protein (LysE YggA)
IM687_RS14595	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
IM687_RS14605	COG4249	Peptidase C14 caspase catalytic subunit p20
IM687_RS14610	COG1132	(ABC) transporter
IM687_RS14650	COG0159	tryptophan synthase activity
IM687_RS14665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM687_RS14675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM687_RS14685	COG4221	oxidoreductase activity
IM687_RS14695	COG2207	Transcriptional regulator
IM687_RS14700	COG3845	ABC transporter
IM687_RS14705	COG4603	Belongs to the binding-protein-dependent transport system permease family
IM687_RS14710	COG1079	Belongs to the binding-protein-dependent transport system permease family
IM687_RS14725	COG1301	dicarboxylic acid transport
IM687_RS14735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IM687_RS14740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IM687_RS14750	COG0490	domain, Protein
IM687_RS14750	COG0471	metal ion transport
IM687_RS14760	COG2814	Major facilitator Superfamily
IM687_RS14780	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM687_RS14780	COG0596	Alpha beta hydrolase
IM687_RS14805	COG1279	arginine transmembrane transporter activity
IM687_RS14830	COG2733	membrane
IM687_RS14835	COG1116	anion transmembrane transporter activity
IM687_RS14850	COG0537	adenosine 5'-monophosphoramidase activity
IM687_RS14860	COG2258	MOSC domain
IM687_RS14875	COG3795	YCII-related domain
IM687_RS14890	COG2851	Citrate transporter
IM687_RS14900	COG1234	tRNA 3'-trailer cleavage
IM687_RS14915	COG3257	ureidoglycine aminohydrolase activity
IM687_RS14920	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IM687_RS14925	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
IM687_RS14930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM687_RS14935	COG0631	protein serine/threonine phosphatase activity
IM687_RS14940	COG2815	serine threonine protein kinase
IM687_RS14940	COG0515	serine threonine protein kinase
IM687_RS14955	COG1643	Atp-dependent helicase
IM687_RS14980	COG0318	PFAM AMP-dependent synthetase and ligase
IM687_RS14985	COG2030	dehydratase
IM687_RS15010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM687_RS15020	COG0443	Heat shock 70 kDa protein
IM687_RS15025	COG2271	Major facilitator Superfamily
IM687_RS15030	COG3622	Belongs to the hyi family
IM687_RS15035	COG2084	Dehydrogenase
IM687_RS15040	COG1968	undecaprenyl-diphosphatase activity
IM687_RS15050	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IM687_RS15060	COG3639	organic phosphonate transmembrane transporter activity
IM687_RS15065	COG3639	organic phosphonate transmembrane transporter activity
IM687_RS15115	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IM687_RS15150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IM687_RS15155	COG0556	nucleotide-excision repair
IM687_RS15175	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IM687_RS15185	COG3842	ATPase activity
IM687_RS15190	COG0590	tRNA wobble adenosine to inosine editing
IM687_RS15195	COG2132	Multicopper oxidase
IM687_RS15200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IM687_RS15200	COG0519	Catalyzes the synthesis of GMP from XMP
IM687_RS15215	COG1570	exodeoxyribonuclease VII activity
IM687_RS15220	COG0739	heme binding
IM687_RS15230	COG0668	transmembrane transport
IM687_RS15245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM687_RS15250	COG1064	alcohol dehydrogenase
IM687_RS15260	COG2356	endonuclease I
IM687_RS15265	COG3647	Membrane
IM687_RS15275	COG2264	protein methyltransferase activity
IM687_RS15290	COG0436	Aminotransferase
IM687_RS15295	COG1045	serine acetyltransferase
IM687_RS15300	COG1160	GTP binding
IM687_RS15310	COG2976	Protein conserved in bacteria
IM687_RS15315	COG0124	histidyl-tRNA synthetase
IM687_RS15320	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IM687_RS15335	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IM687_RS15340	COG0105	UTP biosynthetic process
IM687_RS15355	COG0443	Heat shock 70 kDa protein
IM687_RS15360	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IM687_RS15365	COG0316	Belongs to the HesB IscA family
IM687_RS15375	COG1104	cysteine desulfurase activity
IM687_RS15400	COG3134	Outer membrane lipoprotein
IM687_RS15415	COG1862	Preprotein translocase
IM687_RS15435	COG1278	Cold shock
IM687_RS15445	COG0795	lipopolysaccharide-transporting ATPase activity
IM687_RS15450	COG0795	lipopolysaccharide-transporting ATPase activity
IM687_RS15455	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IM687_RS15485	COG0471	metal ion transport
IM687_RS15485	COG0490	domain, Protein
IM687_RS15490	COG0477	Major facilitator Superfamily
IM687_RS15495	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
IM687_RS15515	COG3081	Nucleoid-associated protein
IM687_RS15520	COG2326	polyphosphate kinase activity
IM687_RS15540	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IM687_RS15545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IM687_RS15585	COG0402	S-adenosylhomocysteine deaminase activity
IM687_RS15590	COG0803	Belongs to the bacterial solute-binding protein 9 family
IM687_RS15600	COG1121	(ABC) transporter
IM687_RS15605	COG1802	Transcriptional regulator
IM687_RS15615	COG2252	PERMEase
IM687_RS15640	COG4266	Belongs to the allantoicase family
IM687_RS15645	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IM687_RS15655	COG2233	PERMEase
IM687_RS15660	COG4651	solute:proton antiporter activity
IM687_RS15660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM687_RS15665	COG2233	PERMEase
IM687_RS15680	COG0840	transmembrane signaling receptor activity
IM687_RS15685	COG1309	transcriptional regulator
IM687_RS15710	COG3300	MHYT domain
IM687_RS15710	COG5001	Diguanylate cyclase
IM687_RS15715	COG0708	Exodeoxyribonuclease III
IM687_RS15735	COG2351	hydroxyisourate hydrolase activity
IM687_RS15740	COG0583	DNA-binding transcription factor activity
IM687_RS15745	COG3960	tartronate-semialdehyde synthase activity
IM687_RS15750	COG3622	Belongs to the hyi family
IM687_RS15755	COG2084	Dehydrogenase
IM687_RS15765	COG0469	pyruvate kinase activity
IM687_RS15770	COG4413	Urea transporter
IM687_RS15780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM687_RS15780	COG1017	nitric oxide dioxygenase activity
IM687_RS15795	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IM687_RS15800	COG3706	GGDEF domain
IM687_RS15820	COG0583	DNA-binding transcription factor activity
IM687_RS15825	COG1279	arginine transmembrane transporter activity
IM687_RS15850	COG1704	LemA family
IM687_RS15880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM687_RS15885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM687_RS15895	COG0459	protein refolding
IM687_RS15900	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IM687_RS15905	COG3030	protein affecting phage T7 exclusion by the F plasmid
IM687_RS15915	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS15935	COG0668	transmembrane transport
IM687_RS15940	COG1666	GTP binding
IM687_RS15945	COG0745	RESPONSE REGULATOR receiver
IM687_RS15955	COG4191	Histidine kinase
IM687_RS15955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM687_RS15960	COG2096	Adenosyltransferase
IM687_RS16000	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IM687_RS16005	COG0653	protein targeting
IM687_RS16045	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IM687_RS16050	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IM687_RS16070	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IM687_RS16075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IM687_RS16085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IM687_RS16090	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IM687_RS16100	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IM687_RS16105	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IM687_RS16125	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IM687_RS16150	COG0559	Belongs to the binding-protein-dependent transport system permease family
IM687_RS16180	COG0318	PFAM AMP-dependent synthetase and ligase
IM687_RS16185	COG4294	response to UV
IM687_RS16190	COG1960	acyl-CoA dehydrogenase activity
IM687_RS16195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM687_RS16200	COG1024	Enoyl-CoA hydratase
IM687_RS16230	COG0789	Transcriptional regulator
IM687_RS16235	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IM687_RS16245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IM687_RS16260	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IM687_RS16290	COG0697	spore germination
IM687_RS16295	COG0288	reversible hydration of carbon dioxide
IM687_RS16300	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IM687_RS16315	COG0456	acetyltransferase
IM687_RS16325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM687_RS16335	COG0019	diaminopimelate decarboxylase activity
IM687_RS16355	COG3008	intermembrane lipid transfer
IM687_RS16360	COG2995	paraquat-inducible protein a
IM687_RS16365	COG2995	paraquat-inducible protein a
IM687_RS16405	COG1183	phosphatidylcholine synthase activity
IM687_RS16410	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IM687_RS16420	COG0028	Belongs to the TPP enzyme family
IM687_RS16440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM687_RS16475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM687_RS16490	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IM687_RS16505	COG2264	protein methyltransferase activity
IM687_RS16525	COG0138	bifunctional purine biosynthesis protein purh
IM687_RS16535	COG5002	protein histidine kinase activity
IM687_RS16535	COG0784	Response regulator, receiver
IM687_RS16535	COG2205	protein histidine kinase activity
IM687_RS16540	COG2124	cytochrome p450
IM687_RS16555	COG0679	Auxin Efflux Carrier
IM687_RS16570	COG0436	Aminotransferase
IM687_RS16575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IM687_RS16580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IM687_RS16590	COG4191	Histidine kinase
IM687_RS16610	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IM687_RS16615	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IM687_RS16620	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IM687_RS16625	COG0166	Belongs to the GPI family
IM687_RS16635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IM687_RS16660	COG1185	polyribonucleotide nucleotidyltransferase activity
IM687_RS16665	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IM687_RS16670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IM687_RS16675	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IM687_RS16680	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IM687_RS16685	COG0195	Participates in both transcription termination and antitermination
IM687_RS16685	COG2251	uridine kinase activity
IM687_RS16690	COG0779	Required for maturation of 30S ribosomal subunits
IM687_RS16705	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IM687_RS16710	COG0149	triose-phosphate isomerase activity
IM687_RS16715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM687_RS16720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IM687_RS16750	COG0505	Belongs to the CarA family
IM687_RS16755	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IM687_RS16760	COG0484	heat shock protein binding
IM687_RS16765	COG0443	Heat shock 70 kDa protein
IM687_RS16770	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IM687_RS16775	COG0497	DNA recombination
IM687_RS16785	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM687_RS16790	COG2914	Belongs to the UPF0125 (RnfH) family
IM687_RS16800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IM687_RS16810	COG1620	l-lactate permease
IM687_RS16815	COG0247	lactate metabolic process
IM687_RS16820	COG1139	Iron-sulfur cluster binding protein
IM687_RS16915	COG2135	peptidase activity
IM687_RS16925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM687_RS16930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM687_RS17130	COG1280	lysine exporter protein (LysE YggA)
IM687_RS17140	COG3842	ATPase activity
IM687_RS17145	COG0366	Alpha amylase catalytic
IM687_RS17170	COG3833	ABC-type maltose transport systems, permease component
IM687_RS17175	COG1175	transmembrane transport
IM687_RS17185	COG0366	Alpha amylase catalytic
IM687_RS17205	COG4580	involved in the transport of maltose and maltodextrins
IM687_RS17225	COG4989	oxidoreductase activity
IM687_RS17235	COG0800	Aldolase
IM687_RS17250	COG1737	Transcriptional regulator
IM687_RS17270	COG2814	Major facilitator Superfamily
IM687_RS17320	COG3154	lipid carrier protein
IM687_RS17325	COG0826	peptidase U32
IM687_RS17330	COG0826	peptidase U32
IM687_RS17340	COG3604	Transcriptional regulator
IM687_RS17370	COG3256	nitric oxide reductase
IM687_RS17375	COG2010	Cytochrome c
IM687_RS17400	COG3391	amine dehydrogenase activity
IM687_RS17405	COG2010	Cytochrome c
IM687_RS17425	COG2010	Cytochrome c
IM687_RS17430	COG0714	Associated with various cellular activities
IM687_RS17435	COG1845	cytochrome c oxidase, subunit III
IM687_RS17445	COG0535	radical SAM domain protein
IM687_RS17450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IM687_RS17450	COG1648	precorrin-2 dehydrogenase activity
IM687_RS17465	COG0517	IMP dehydrogenase activity
IM687_RS17465	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IM687_RS17465	COG0617	tRNA 3'-terminal CCA addition
IM687_RS17475	COG0840	transmembrane signaling receptor activity
IM687_RS17480	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS17500	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IM687_RS17515	COG4263	nitrous-oxide reductase activity
IM687_RS17520	COG0348	domain, Protein
IM687_RS17520	COG3901	Regulator of nitric oxide reductase transcription
IM687_RS17525	COG1960	acyl-CoA dehydrogenase activity
IM687_RS17540	COG3189	MarR family transcriptional regulator
IM687_RS17555	COG0492	ferredoxin-NADP+ reductase activity
IM687_RS17560	COG1760	l-serine dehydratase
IM687_RS17580	COG2154	pterin-4-alpha-carbinolamine dehydratase
IM687_RS17595	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
IM687_RS17610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IM687_RS17615	COG0402	S-adenosylhomocysteine deaminase activity
IM687_RS17625	COG1607	acyl-coa hydrolase
IM687_RS17630	COG2824	Alkylphosphonate utilization operon protein PhnA
IM687_RS17635	COG1278	Cold shock
IM687_RS17655	COG1079	Belongs to the binding-protein-dependent transport system permease family
IM687_RS17665	COG3845	ABC transporter
IM687_RS17700	COG0346	lactoylglutathione lyase activity
IM687_RS17710	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM687_RS17735	COG1309	transcriptional regulator
IM687_RS17740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM687_RS17745	COG1335	isochorismatase
IM687_RS17750	COG0251	oxidation-reduction process
IM687_RS17755	COG0596	Alpha beta hydrolase
IM687_RS17760	COG0778	Nitroreductase
IM687_RS17765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IM687_RS17795	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IM687_RS17805	COG2814	Major facilitator Superfamily
IM687_RS17810	COG1309	transcriptional regulator
IM687_RS17820	COG2217	Heavy metal translocating P-type atpase
IM687_RS17830	COG0840	transmembrane signaling receptor activity
IM687_RS17840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM687_RS17845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM687_RS17860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IM687_RS17860	COG2169	Transcriptional regulator
IM687_RS17870	COG0084	hydrolase, TatD family'
IM687_RS17875	COG0840	transmembrane signaling receptor activity
IM687_RS17885	COG3023	N-Acetylmuramoyl-L-alanine amidase
IM687_RS17890	COG1515	deoxyribonuclease V activity
IM687_RS17900	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IM687_RS17905	COG0180	Tryptophanyl-tRNA synthetase
IM687_RS17910	COG2945	thiolester hydrolase activity
IM687_RS17935	COG1252	NADH dehydrogenase
IM687_RS18010	COG3300	MHYT domain
IM687_RS18010	COG5001	Diguanylate cyclase
IM687_RS18015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IM687_RS18020	COG0305	Participates in initiation and elongation during chromosome replication
IM687_RS18025	COG0359	binds to the 23S rRNA
IM687_RS18035	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IM687_RS18040	COG0360	Binds together with S18 to 16S ribosomal RNA
IM687_RS18045	COG4191	Histidine kinase
IM687_RS18045	COG0784	Response regulator, receiver
IM687_RS18050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM687_RS18070	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IM687_RS18075	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IM687_RS18080	COG0330	HflC and HflK could
IM687_RS18085	COG0330	HflC and HflK could
IM687_RS18090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IM687_RS18095	COG1923	regulation of RNA biosynthetic process
IM687_RS18100	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IM687_RS18105	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IM687_RS18110	COG0860	N-Acetylmuramoyl-L-alanine amidase
IM687_RS18115	COG0802	atpase or kinase
IM687_RS18120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IM687_RS18120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IM687_RS18145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IM687_RS18155	COG0531	amino acid
IM687_RS18160	COG4303	Ethanolamine ammonia lyase large subunit
IM687_RS18180	COG3228	Belongs to the MtfA family
IM687_RS18200	COG2197	response regulator
IM687_RS18205	COG3851	Histidine kinase
IM687_RS18215	COG0745	RESPONSE REGULATOR receiver
IM687_RS18225	COG2198	Histidine kinase
IM687_RS18225	COG0643	Histidine kinase
IM687_RS18230	COG0840	transmembrane signaling receptor activity
IM687_RS18235	COG0835	chemotaxis
IM687_RS18255	COG5001	Diguanylate cyclase
IM687_RS18255	COG3300	MHYT domain
IM687_RS18265	COG0076	glutamate decarboxylase activity
IM687_RS18270	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IM687_RS18295	COG1722	exodeoxyribonuclease VII activity
IM687_RS18300	COG0142	geranyltranstransferase activity
IM687_RS18305	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IM687_RS18325	COG1028	Short-chain dehydrogenase reductase Sdr
IM687_RS18335	COG1643	Atp-dependent helicase
IM687_RS18355	COG1522	sequence-specific DNA binding
IM687_RS18405	COG0829	nickel cation binding
IM687_RS18410	COG0831	urea catabolic process
IM687_RS18420	COG0832	Belongs to the urease beta subunit family
IM687_RS18425	COG0804	urea catabolic process
IM687_RS18430	COG1953	Uracil, thiamine, allantoin
IM687_RS18440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IM687_RS18450	COG2814	Major facilitator Superfamily
IM687_RS18455	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IM687_RS18470	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IM687_RS18475	COG0830	nickel cation binding
IM687_RS18480	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IM687_RS18495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IM687_RS18500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM687_RS18515	COG1960	acyl-CoA dehydrogenase activity
IM687_RS18520	COG2205	protein histidine kinase activity
IM687_RS18520	COG3437	response regulator, receiver
IM687_RS18520	COG3850	Histidine kinase
IM687_RS18520	COG4999	Histidine kinase
IM687_RS18525	COG0351	phosphomethylpyrimidine kinase
IM687_RS18525	COG0352	thiamine-phosphate diphosphorylase activity
IM687_RS18530	COG0352	thiamine-phosphate diphosphorylase activity
IM687_RS18535	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IM687_RS18550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IM687_RS18555	COG1702	phosphate starvation-inducible protein PhoH
IM687_RS18560	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IM687_RS18565	COG4535	Mg2 and Co2 transporter CorC
IM687_RS18570	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IM687_RS18585	COG0495	leucyl-tRNA aminoacylation
IM687_RS18600	COG3036	rescue of stalled ribosome
IM687_RS18605	COG2951	lytic endotransglycosylase activity
IM687_RS18615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IM687_RS18620	COG0321	lipoyl(octanoyl) transferase activity
IM687_RS18625	COG2921	Belongs to the UPF0250 family
IM687_RS18630	COG1686	Belongs to the peptidase S11 family
IM687_RS18640	COG2951	lytic endotransglycosylase activity
IM687_RS18645	COG0772	Belongs to the SEDS family
IM687_RS18650	COG0768	penicillin binding
IM687_RS18655	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IM687_RS18665	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IM687_RS18670	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IM687_RS18675	COG0586	Pfam SNARE associated Golgi protein
IM687_RS18685	COG1346	cytolysis
IM687_RS18705	COG0702	epimerase
IM687_RS18710	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IM687_RS18720	COG1162	GTPase activity
IM687_RS18725	COG1360	Flagellar Motor Protein
IM687_RS18730	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IM687_RS18745	COG0688	phosphatidylethanolamine metabolic process
IM687_RS18755	COG2200	EAL domain
IM687_RS18760	COG1063	alcohol dehydrogenase
IM687_RS18765	COG0560	Phosphoserine phosphatase
IM687_RS18765	COG3830	Belongs to the UPF0237 family
IM687_RS18800	COG3150	esterase
IM687_RS18805	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IM687_RS18815	COG0494	nUDIX hydrolase
IM687_RS18830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM687_RS18840	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IM687_RS18840	COG0662	Cupin 2, conserved barrel domain protein
IM687_RS18845	COG0438	transferase activity, transferring glycosyl groups
IM687_RS18875	COG1696	Membrane protein involved in D-alanine export
IM687_RS18910	COG0438	transferase activity, transferring glycosyl groups
IM687_RS18915	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IM687_RS18940	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IM687_RS18945	COG1538	Outer membrane efflux protein
IM687_RS18950	COG1519	Transferase
IM687_RS18965	COG0667	Aldo Keto reductase
IM687_RS18975	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IM687_RS18975	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IM687_RS18990	COG1132	(ABC) transporter
IM687_RS19010	COG3562	capsule polysaccharide
IM687_RS19020	COG1215	transferase activity, transferring glycosyl groups
IM687_RS19025	COG2192	nodulation
IM687_RS19050	COG0438	transferase activity, transferring glycosyl groups
IM687_RS19055	COG0859	PFAM glycosyl transferase family 9
IM687_RS19060	COG0859	PFAM glycosyl transferase family 9
IM687_RS19070	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IM687_RS19095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM687_RS19100	COG1960	acyl-CoA dehydrogenase activity
IM687_RS19105	COG3706	GGDEF domain
IM687_RS19110	COG1960	acyl-CoA dehydrogenase activity
IM687_RS19130	COG1073	alpha beta
IM687_RS19130	COG2226	methyltransferase
IM687_RS19135	COG0156	8-amino-7-oxononanoate synthase activity
IM687_RS19140	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IM687_RS19145	COG1040	competence protein
IM687_RS19150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IM687_RS19155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IM687_RS19190	COG1304	FMN binding
IM687_RS19200	COG1960	acyl-CoA dehydrogenase activity
IM687_RS19205	COG3263	regulation of cellular component size
IM687_RS19210	COG1196	nuclear chromosome segregation
IM687_RS19210	COG3264	Mechanosensitive ion channel
IM687_RS19215	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IM687_RS19220	COG5002	protein histidine kinase activity
IM687_RS19230	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IM687_RS19235	COG2205	protein histidine kinase activity
IM687_RS19235	COG2198	Histidine kinase
IM687_RS19235	COG0784	Response regulator, receiver
IM687_RS19265	COG0330	HflC and HflK could
IM687_RS19295	COG4774	siderophore transport
IM687_RS19305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM687_RS19315	COG2721	sulfolactate sulfo-lyase activity
IM687_RS19325	COG1012	belongs to the aldehyde dehydrogenase family
IM687_RS19330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM687_RS19360	COG0583	DNA-binding transcription factor activity
IM687_RS19370	COG1917	Cupin 2, conserved barrel domain protein
IM687_RS19370	COG4977	sequence-specific DNA binding
IM687_RS19385	COG1609	Transcriptional regulator
IM687_RS19390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM687_RS19400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IM687_RS19450	COG0840	transmembrane signaling receptor activity
IM687_RS19480	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM687_RS19495	COG0513	Belongs to the DEAD box helicase family
IM687_RS19500	COG1289	transmembrane transporter activity
IM687_RS19510	COG2081	HI0933 family
IM687_RS19525	COG5001	Diguanylate cyclase
IM687_RS19550	COG0191	fructose-bisphosphate aldolase activity
IM687_RS19565	COG0126	phosphoglycerate kinase activity
IM687_RS19570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM687_RS19575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IM687_RS19580	COG0583	DNA-binding transcription factor activity
IM687_RS19595	COG2226	methyltransferase
IM687_RS19600	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IM687_RS19620	COG0842	Transport permease protein
IM687_RS19625	COG1131	(ABC) transporter
IM687_RS19630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM687_RS19635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IM687_RS19655	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IM687_RS19660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IM687_RS19665	COG0513	Belongs to the DEAD box helicase family
IM687_RS19680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM687_RS19685	COG2353	YceI-like domain
IM687_RS19690	COG3038	cytochrome b561
IM687_RS19700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IM687_RS19710	COG2201	protein-glutamate methylesterase activity
IM687_RS19715	COG0784	Response regulator, receiver
IM687_RS19715	COG0643	Histidine kinase
IM687_RS19715	COG2198	Histidine kinase
IM687_RS19755	COG1678	Uncharacterized ACR, COG1678
IM687_RS19770	COG0540	Belongs to the ATCase OTCase family
IM687_RS19825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IM687_RS19830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IM687_RS19830	COG2813	Specifically methylates the guanine in position
IM687_RS19840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IM687_RS19845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IM687_RS19870	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IM687_RS19885	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IM687_RS19890	COG2022	thiamine diphosphate biosynthetic process
IM687_RS19900	COG2363	Small membrane protein
IM687_RS19905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM687_RS19925	COG2177	Part of the ABC transporter FtsEX involved in
IM687_RS19930	COG2884	Cell division ATP-binding protein ftsE
IM687_RS19935	COG0552	protein localization to endoplasmic reticulum
IM687_RS19940	COG0612	Peptidase, M16
IM687_RS19945	COG0612	Peptidase, M16
IM687_RS19950	COG0742	ribosomal rna small subunit methyltransferase
IM687_RS19980	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IM687_RS19985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IM687_RS19990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IM687_RS20010	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM687_RS20020	COG0693	protein deglycase activity
IM687_RS20035	COG0129	dihydroxy-acid dehydratase activity
IM687_RS20065	COG0584	glycerophosphoryl diester phosphodiesterase
IM687_RS20075	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IM687_RS20090	COG0704	Plays a role in the regulation of phosphate uptake
IM687_RS20095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IM687_RS20100	COG0573	inorganic phosphate transmembrane transporter activity
IM687_RS20115	COG1607	acyl-coa hydrolase
IM687_RS20120	COG2203	Gaf domain
IM687_RS20120	COG5001	Diguanylate cyclase
IM687_RS20120	COG4251	negative regulation of phosphorylation
IM687_RS20120	COG3706	GGDEF domain
IM687_RS20135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IM687_RS20140	COG1074	ATP-dependent DNA helicase activity
IM687_RS20145	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IM687_RS20160	COG3180	Ammonia monooxygenase
IM687_RS20195	COG2203	Gaf domain
IM687_RS20195	COG3706	GGDEF domain
IM687_RS20195	COG4251	negative regulation of phosphorylation
IM687_RS20195	COG5001	Diguanylate cyclase
IM687_RS20200	COG0840	transmembrane signaling receptor activity
IM687_RS20215	COG2358	TRAP transporter, solute receptor (TAXI family
IM687_RS20225	COG0700	Nucleoside recognition
IM687_RS20245	COG2204	response regulator
IM687_RS20250	COG5002	protein histidine kinase activity
IM687_RS20260	COG3023	N-Acetylmuramoyl-L-alanine amidase
IM687_RS20285	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IM687_RS20290	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IM687_RS20290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IM687_RS20305	COG1178	ABC-type Fe3 transport system permease component
IM687_RS20315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM687_RS20325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM687_RS20330	COG0006	proline dipeptidase activity
IM687_RS20335	COG3079	Belongs to the UPF0149 family
IM687_RS20355	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IM687_RS20380	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IM687_RS20390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM687_RS20395	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IM687_RS20400	COG4942	peptidase
IM687_RS20405	COG0793	Belongs to the peptidase S41A family
IM687_RS20410	COG2861	carbohydrate metabolic process
IM687_RS20425	COG0107	imidazoleglycerol-phosphate synthase activity
IM687_RS20430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IM687_RS20445	COG0131	Imidazoleglycerol-phosphate dehydratase
IM687_RS20450	COG3707	response regulator
IM687_RS20455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM687_RS20465	COG1116	anion transmembrane transporter activity
IM687_RS20480	COG1194	a g-specific adenine glycosylase
IM687_RS20485	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IM687_RS20495	COG1525	nuclease
IM687_RS20530	COG0676	glucose-6-phosphate 1-epimerase activity
IM687_RS20595	COG2204	response regulator
IM687_RS20615	COG3675	Pfam Lipase (class 3)
IM687_RS20625	COG3675	Pfam Lipase (class 3)
IM687_RS20650	COG0840	transmembrane signaling receptor activity
IM687_RS20665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IM687_RS20685	COG3052	prosthetic group binding
IM687_RS20690	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IM687_RS20700	COG4221	oxidoreductase activity
IM687_RS20705	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IM687_RS20720	COG2358	TRAP transporter, solute receptor (TAXI family
IM687_RS20760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM687_RS20770	COG3360	Dodecin
IM687_RS20775	COG0625	glutathione transferase activity
IM687_RS20795	COG4085	toxin activity
IM687_RS20795	COG1525	nuclease
IM687_RS20795	COG0737	Belongs to the 5'-nucleotidase family
IM687_RS20810	COG3340	Belongs to the peptidase S51 family
IM687_RS20815	COG1132	(ABC) transporter
IM687_RS20860	COG2323	membrane
IM687_RS20865	COG0583	DNA-binding transcription factor activity
IM687_RS20900	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IM687_RS20905	COG0339	signal peptide processing
IM687_RS20935	COG0659	secondary active sulfate transmembrane transporter activity
IM687_RS20945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IM687_RS20950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM687_RS20955	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IM687_RS20985	COG0109	protoheme IX farnesyltransferase activity
IM687_RS21010	COG1595	DNA-templated transcription, initiation
IM687_RS21025	COG0523	cobalamin synthesis protein
IM687_RS21040	COG4251	negative regulation of phosphorylation
IM687_RS21045	COG0784	Response regulator, receiver
IM687_RS21060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IM687_RS21065	COG1349	DNA-binding transcription factor activity
IM687_RS21075	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IM687_RS21080	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IM687_RS21085	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IM687_RS21090	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IM687_RS21095	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IM687_RS21100	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IM687_RS21105	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IM687_RS21115	COG0356	it plays a direct role in the translocation of protons across the membrane
IM687_RS21125	COG1475	DNA binding
IM687_RS21130	COG1192	Involved in chromosome partitioning
IM687_RS21135	COG0357	Ribosomal RNA small subunit methyltransferase G
IM687_RS21140	COG0445	tRNA wobble uridine modification
IM687_RS21145	COG1320	monovalent cation:proton antiporter activity
IM687_RS21160	COG0651	ATP synthesis coupled electron transport
IM687_RS21165	COG1006	Multisubunit Na H antiporter MnhC subunit
IM687_RS21170	COG2111	Na H antiporter
IM687_RS21175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IM687_RS21175	COG2111	Na H antiporter
IM687_RS21180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IM687_RS21185	COG0706	membrane insertase activity
IM687_RS21190	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IM687_RS21195	COG0594	ribonuclease P activity
IM687_RS21200	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IM687_RS21220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM687_RS21225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IM687_RS21445	COG0582	viral genome integration into host DNA
IM687_RS21460	COG4680	protein conserved in bacteria
IM687_RS21500	COG1131	(ABC) transporter
IM687_RS21510	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IM687_RS21535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IM687_RS21555	COG1357	PFAM Pentapeptide repeats (8 copies)
IM687_RS21585	COG3077	Addiction module antitoxin, RelB DinJ family
IM687_RS21590	COG3041	Addiction module toxin RelE StbE family
IM687_RS21655	COG2894	cell division
IM687_RS21660	COG0305	Participates in initiation and elongation during chromosome replication