locus-tag	class	description
SDZ_RS00040	COG1442	glycosyl transferase family 8
SDZ_RS00045	COG1216	Glycosyl transferase, family 2
SDZ_RS00045	COG1442	glycosyl transferase family 8
SDZ_RS00060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SDZ_RS00080	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SDZ_RS00090	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SDZ_RS00175	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
SDZ_RS00175	COG0028	Belongs to the TPP enzyme family
SDZ_RS00195	COG0582	viral genome integration into host DNA
SDZ_RS00260	COG1484	DNA-dependent DNA replication
SDZ_RS00355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SDZ_RS00380	COG1132	(ABC) transporter
SDZ_RS00385	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SDZ_RS00435	COG1598	PFAM Uncharacterised protein family UPF0150
SDZ_RS00445	COG1403	HNH endonuclease
SDZ_RS00495	COG3267	Type II secretory pathway component ExeA
SDZ_RS00495	COG3409	Peptidoglycan-binding domain 1 protein
SDZ_RS00515	COG1484	DNA-dependent DNA replication
SDZ_RS00520	COG1484	DNA-dependent DNA replication
SDZ_RS00545	COG4942	peptidase
SDZ_RS00555	COG1122	ATPase activity
SDZ_RS00585	COG3106	COG3106 Predicted ATPase
SDZ_RS00610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SDZ_RS00615	COG2011	ABC-type metal ion transport system permease component
SDZ_RS00620	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
SDZ_RS00625	COG3620	sequence-specific DNA binding
SDZ_RS00635	COG1464	Belongs to the NlpA lipoprotein family
SDZ_RS00640	COG0322	excinuclease ABC activity
SDZ_RS00645	COG0840	transmembrane signaling receptor activity
SDZ_RS00650	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SDZ_RS00650	COG0463	Glycosyl transferase, family 2
SDZ_RS00670	COG0546	phosphoglycolate phosphatase activity
SDZ_RS00680	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SDZ_RS00690	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SDZ_RS00715	COG1192	Involved in chromosome partitioning
SDZ_RS00725	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SDZ_RS00730	COG1663	tetraacyldisaccharide 4'-kinase activity
SDZ_RS00740	COG0242	peptide deformylase activity
SDZ_RS00750	COG1592	Rubrerythrin
SDZ_RS00765	COG2814	Major facilitator Superfamily
SDZ_RS00770	COG4145	pantothenate transmembrane transporter activity
SDZ_RS00780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SDZ_RS00825	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SDZ_RS00830	COG0285	dihydrofolate synthase activity
SDZ_RS00850	COG0463	Glycosyl transferase, family 2
SDZ_RS00860	COG0101	tRNA pseudouridine synthase activity
SDZ_RS00865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SDZ_RS00885	COG0366	Alpha amylase catalytic
SDZ_RS00890	COG2920	part of a sulfur-relay system
SDZ_RS00905	COG1027	Aspartate ammonia-lyase
SDZ_RS00910	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SDZ_RS00915	COG0385	Bile acid
SDZ_RS00920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SDZ_RS00920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SDZ_RS00930	COG0539	negative regulation of cytoplasmic translation
SDZ_RS00945	COG2011	ABC-type metal ion transport system permease component
SDZ_RS00950	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SDZ_RS00955	COG1473	amidohydrolase
SDZ_RS00960	COG0776	regulation of translation
SDZ_RS00970	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
SDZ_RS00975	COG0284	orotidine-5'-phosphate decarboxylase activity
SDZ_RS01010	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SDZ_RS01030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SDZ_RS01045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SDZ_RS01045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SDZ_RS01070	COG5001	Diguanylate cyclase
SDZ_RS01075	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
SDZ_RS01095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SDZ_RS01100	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SDZ_RS01110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SDZ_RS01115	COG1882	Formate acetyltransferase
SDZ_RS01125	COG1979	alcohol dehydrogenase
SDZ_RS01135	COG0534	Mate efflux family protein
SDZ_RS01140	COG0347	Belongs to the P(II) protein family
SDZ_RS01145	COG0004	ammonium transporteR
SDZ_RS01180	COG2814	Major facilitator Superfamily
SDZ_RS01200	COG0674	pyruvate-flavodoxin oxidoreductase activity
SDZ_RS01205	COG1013	pyruvate-flavodoxin oxidoreductase activity
SDZ_RS01210	COG0493	'glutamate synthase
SDZ_RS01225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SDZ_RS01230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SDZ_RS01255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SDZ_RS01275	COG4953	penicillin-binding protein 1C
SDZ_RS01285	COG0563	adenylate kinase activity
SDZ_RS01290	COG0326	Molecular chaperone. Has ATPase activity
SDZ_RS01295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SDZ_RS01315	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SDZ_RS01330	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SDZ_RS01420	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SDZ_RS01425	COG1074	ATP-dependent DNA helicase activity
SDZ_RS01430	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SDZ_RS01445	COG0037	tRNA processing
SDZ_RS01450	COG0589	response to stress
SDZ_RS01470	COG1739	Uncharacterized protein family UPF0029
SDZ_RS01490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SDZ_RS01500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SDZ_RS01515	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SDZ_RS01520	COG0740	serine-type endopeptidase activity
SDZ_RS01540	COG0569	domain protein
SDZ_RS01540	COG2985	domain, Protein
SDZ_RS01550	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SDZ_RS01560	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
SDZ_RS01570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SDZ_RS01575	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SDZ_RS01580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SDZ_RS01585	COG0131	Imidazoleglycerol-phosphate dehydratase
SDZ_RS01585	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SDZ_RS01590	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SDZ_RS01595	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SDZ_RS01600	COG0107	imidazoleglycerol-phosphate synthase activity
SDZ_RS01605	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SDZ_RS01605	COG0140	phosphoribosyl-ATP diphosphatase activity
SDZ_RS01620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SDZ_RS01625	COG4286	Uncharacterised protein family (UPF0160)
SDZ_RS01640	COG0385	Bile acid
SDZ_RS01645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SDZ_RS01680	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SDZ_RS01725	COG0167	dihydroorotate dehydrogenase activity
SDZ_RS01735	COG0308	aminopeptidase N
SDZ_RS01740	COG0793	Belongs to the peptidase S41A family
SDZ_RS01745	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
SDZ_RS01760	COG2816	NAD+ diphosphatase activity
SDZ_RS01765	COG0492	ferredoxin-NADP+ reductase activity
SDZ_RS01770	COG1876	peptidase activity
SDZ_RS01780	COG2176	DNA-directed DNA polymerase activity
SDZ_RS01785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SDZ_RS01800	COG1570	exodeoxyribonuclease VII activity
SDZ_RS01840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SDZ_RS01865	COG1199	ATP-dependent helicase activity
SDZ_RS01870	COG0826	peptidase U32
SDZ_RS01890	COG0537	adenosine 5'-monophosphoramidase activity
SDZ_RS01900	COG0488	(ABC) transporter
SDZ_RS01905	COG1227	inorganic diphosphatase activity
SDZ_RS01910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SDZ_RS01915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SDZ_RS01920	COG2233	PERMEase
SDZ_RS01930	COG0840	transmembrane signaling receptor activity
SDZ_RS01935	COG1408	metallophosphoesterase
SDZ_RS01955	COG0675	Transposase, IS605 OrfB family
SDZ_RS01960	COG2195	Cleaves the N-terminal amino acid of tripeptides
SDZ_RS01965	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SDZ_RS01970	COG0148	phosphopyruvate hydratase activity
SDZ_RS01980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SDZ_RS02010	COG1643	Atp-dependent helicase
SDZ_RS02015	COG3263	regulation of cellular component size
SDZ_RS02030	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SDZ_RS02055	COG1187	pseudouridine synthase activity
SDZ_RS02060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SDZ_RS02065	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SDZ_RS02070	COG1403	HNH endonuclease
SDZ_RS02090	COG0538	isocitrate dehydrogenase activity
SDZ_RS02120	COG2915	High frequency lysogenization protein hflD homolog
SDZ_RS02125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SDZ_RS02130	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SDZ_RS02155	COG2910	NAD(P)H-binding
SDZ_RS02160	COG1959	2 iron, 2 sulfur cluster binding
SDZ_RS02170	COG1482	cell wall glycoprotein biosynthetic process
SDZ_RS02185	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
SDZ_RS02190	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
SDZ_RS02205	COG3842	ATPase activity
SDZ_RS02210	COG2942	2-epimerase
SDZ_RS02220	COG0395	ABC-type sugar transport system, permease component
SDZ_RS02225	COG1175	transmembrane transport
SDZ_RS02250	COG3041	Addiction module toxin RelE StbE family
SDZ_RS02280	COG0438	transferase activity, transferring glycosyl groups
SDZ_RS02315	COG2894	cell division
SDZ_RS02340	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
SDZ_RS02345	COG2326	polyphosphate kinase activity
SDZ_RS02425	COG3451	type IV secretory pathway VirB4
SDZ_RS02460	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SDZ_RS02480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SDZ_RS02515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SDZ_RS02605	COG1674	ftsk spoiiie
SDZ_RS02620	COG0740	serine-type endopeptidase activity
SDZ_RS02630	COG0084	hydrolase, TatD family'
SDZ_RS02645	COG1403	HNH endonuclease
SDZ_RS02700	COG2356	endonuclease I
SDZ_RS02705	COG0673	inositol 2-dehydrogenase activity
SDZ_RS02715	COG0840	transmembrane signaling receptor activity
SDZ_RS02725	COG3328	transposase activity
SDZ_RS02745	COG2356	endonuclease I
SDZ_RS02775	COG1353	crispr-associated protein
SDZ_RS02785	COG1337	RAMP superfamily
SDZ_RS02825	COG3604	Transcriptional regulator
SDZ_RS02830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SDZ_RS02895	COG3620	sequence-specific DNA binding
SDZ_RS02940	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SDZ_RS02990	COG2814	Major facilitator Superfamily
SDZ_RS03130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SDZ_RS03135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SDZ_RS03140	COG0708	Exodeoxyribonuclease III
SDZ_RS03145	COG1538	Outer membrane efflux protein
SDZ_RS03150	COG1091	dTDP-4-dehydrorhamnose reductase activity
SDZ_RS03155	COG2195	Cleaves the N-terminal amino acid of tripeptides
SDZ_RS03160	COG1136	(ABC) transporter
SDZ_RS03160	COG0577	efflux transmembrane transporter activity
SDZ_RS03165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SDZ_RS03170	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SDZ_RS03175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SDZ_RS03200	COG1115	amino acid carrier protein
SDZ_RS03210	COG2894	cell division
SDZ_RS03215	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SDZ_RS03220	COG4783	chaperone-mediated protein folding
SDZ_RS03240	COG0527	aspartate kinase activity
SDZ_RS03250	COG0191	fructose-bisphosphate aldolase activity
SDZ_RS03255	COG0126	phosphoglycerate kinase activity
SDZ_RS03285	COG0640	Transcriptional regulator
SDZ_RS03290	COG0446	pyridine nucleotide-disulphide oxidoreductase
SDZ_RS03345	COG1518	maintenance of DNA repeat elements
SDZ_RS03410	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SDZ_RS03450	COG2356	endonuclease I
SDZ_RS03455	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SDZ_RS03460	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SDZ_RS03460	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SDZ_RS03465	COG1611	Belongs to the LOG family
SDZ_RS03480	COG1684	flagellar biosynthetic protein fliR
SDZ_RS03485	COG1987	bacterial-type flagellum assembly
SDZ_RS03540	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SDZ_RS03555	COG0252	asparaginase activity
SDZ_RS03570	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SDZ_RS03575	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SDZ_RS03590	COG3345	alpha-galactosidase
SDZ_RS03625	COG0530	calcium, potassium:sodium antiporter activity
SDZ_RS03630	COG2910	NAD(P)H-binding
SDZ_RS03635	COG1959	2 iron, 2 sulfur cluster binding
SDZ_RS03640	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDZ_RS03645	COG1129	ABC transporter
SDZ_RS03665	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SDZ_RS03690	COG1132	(ABC) transporter
SDZ_RS03700	COG1448	Aminotransferase
SDZ_RS03705	COG0534	Mate efflux family protein
SDZ_RS03710	COG1126	abc transporter atp-binding protein
SDZ_RS03715	COG0765	amino acid transport
SDZ_RS03720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDZ_RS03735	COG3842	ATPase activity
SDZ_RS03740	COG3833	ABC-type maltose transport systems, permease component
SDZ_RS03745	COG1175	transmembrane transport
SDZ_RS03750	COG2182	Extracellular solute-binding protein
SDZ_RS03765	COG0735	belongs to the Fur family
SDZ_RS03780	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SDZ_RS03795	COG1966	Carbon starvation protein
SDZ_RS03805	COG0675	Transposase, IS605 OrfB family
SDZ_RS03820	COG4106	trans-aconitate 2-methyltransferase activity
SDZ_RS03835	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SDZ_RS03845	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SDZ_RS03850	COG1966	Carbon starvation protein
SDZ_RS03855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SDZ_RS03870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SDZ_RS03880	COG0110	maltose O-acetyltransferase activity
SDZ_RS03890	COG2890	protein-(glutamine-N5) methyltransferase activity
SDZ_RS03895	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SDZ_RS03940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SDZ_RS03995	COG0675	Transposase, IS605 OrfB family
SDZ_RS04005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SDZ_RS04010	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SDZ_RS04015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SDZ_RS04020	COG0617	tRNA 3'-terminal CCA addition
SDZ_RS04025	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SDZ_RS04035	COG0012	GTP binding
SDZ_RS04070	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SDZ_RS04080	COG1136	(ABC) transporter
SDZ_RS04140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SDZ_RS04160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SDZ_RS04175	COG1119	ATPase activity
SDZ_RS04200	COG2885	chlorophyll binding
SDZ_RS04205	COG0823	Involved in the tonB-independent uptake of proteins
SDZ_RS04215	COG0848	biopolymer transport protein
SDZ_RS04220	COG0811	peptide transport
SDZ_RS04225	COG0824	Thioesterase
SDZ_RS04230	COG2255	four-way junction helicase activity
SDZ_RS04240	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SDZ_RS04250	COG0803	Belongs to the bacterial solute-binding protein 9 family
SDZ_RS04255	COG1121	(ABC) transporter
SDZ_RS04260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SDZ_RS04270	COG0697	spore germination
SDZ_RS04290	COG1484	DNA-dependent DNA replication
SDZ_RS04310	COG0741	lytic transglycosylase activity
SDZ_RS04315	COG0733	neurotransmitter:sodium symporter activity
SDZ_RS04320	COG0733	neurotransmitter:sodium symporter activity
SDZ_RS04325	COG0733	neurotransmitter:sodium symporter activity
SDZ_RS04330	COG1185	polyribonucleotide nucleotidyltransferase activity
SDZ_RS04340	COG1609	Transcriptional regulator
SDZ_RS04345	COG1070	Carbohydrate kinase
SDZ_RS04350	COG4214	carbohydrate transport
SDZ_RS04360	COG4213	ABC transporter substrate-binding protein
SDZ_RS04370	COG0835	chemotaxis
SDZ_RS04380	COG1192	Involved in chromosome partitioning
SDZ_RS04385	COG2885	chlorophyll binding
SDZ_RS04390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SDZ_RS04395	COG2201	protein-glutamate methylesterase activity
SDZ_RS04400	COG0784	Response regulator, receiver
SDZ_RS04400	COG0643	Histidine kinase
SDZ_RS04400	COG2198	Histidine kinase
SDZ_RS04405	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
SDZ_RS04435	COG3098	single-species biofilm formation
SDZ_RS04440	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SDZ_RS04500	COG2249	NAD(P)H dehydrogenase (quinone) activity
SDZ_RS04505	COG0776	regulation of translation
SDZ_RS04515	COG3885	ferrous iron binding
SDZ_RS04515	COG2078	PFAM AMMECR1 domain protein
SDZ_RS04520	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SDZ_RS04525	COG1085	galactose-1-phosphate uridylyltransferase
SDZ_RS04530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SDZ_RS04535	COG1609	Transcriptional regulator
SDZ_RS04540	COG1560	Kdo2-lipid A biosynthetic process
SDZ_RS04550	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SDZ_RS04565	COG2182	Extracellular solute-binding protein
SDZ_RS04600	COG0675	Transposase, IS605 OrfB family
SDZ_RS04605	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SDZ_RS04615	COG0784	Response regulator, receiver
SDZ_RS04615	COG0835	chemotaxis
SDZ_RS04630	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDZ_RS04645	COG2390	Transcriptional regulator
SDZ_RS04650	COG2390	Transcriptional regulator
SDZ_RS04665	COG1373	ATPase (AAA superfamily
SDZ_RS04675	COG3409	Peptidoglycan-binding domain 1 protein
SDZ_RS04675	COG3267	Type II secretory pathway component ExeA
SDZ_RS04695	COG0617	tRNA 3'-terminal CCA addition
SDZ_RS04710	COG1794	racemase activity, acting on amino acids and derivatives
SDZ_RS04720	COG1968	undecaprenyl-diphosphatase activity
SDZ_RS04730	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SDZ_RS04735	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SDZ_RS04740	COG1484	DNA-dependent DNA replication
SDZ_RS04760	COG1490	D-aminoacyl-tRNA deacylase activity
SDZ_RS04775	COG4989	oxidoreductase activity
SDZ_RS04780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SDZ_RS04840	COG0622	Phosphoesterase
SDZ_RS04850	COG2182	Extracellular solute-binding protein
SDZ_RS04855	COG4580	involved in the transport of maltose and maltodextrins
SDZ_RS04860	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDZ_RS04865	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDZ_RS04870	COG1129	ABC transporter
SDZ_RS04875	COG1879	ABC-type sugar transport system periplasmic component
SDZ_RS04885	COG0857	belongs to the CobB CobQ family
SDZ_RS04885	COG0280	phosphate acetyltransferase
SDZ_RS04890	COG1090	epimerase
SDZ_RS04895	COG0235	Class ii aldolase
SDZ_RS04900	COG1609	Transcriptional regulator
SDZ_RS04915	COG1748	Saccharopine dehydrogenase
SDZ_RS04930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SDZ_RS04935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SDZ_RS04945	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SDZ_RS04950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SDZ_RS04955	COG0416	fatty acid biosynthetic process
SDZ_RS04975	COG0546	phosphoglycolate phosphatase activity
SDZ_RS04995	COG1530	ribonuclease E activity
SDZ_RS05000	COG0517	IMP dehydrogenase activity
SDZ_RS05010	COG1373	ATPase (AAA superfamily
SDZ_RS05015	COG0483	inositol monophosphate 1-phosphatase activity
SDZ_RS05035	COG3479	Phenolic acid decarboxylase
SDZ_RS05040	COG1695	Transcriptional regulator
SDZ_RS05045	COG3300	MHYT domain
SDZ_RS05045	COG5001	Diguanylate cyclase
SDZ_RS05070	COG0693	protein deglycase activity
SDZ_RS05080	COG1067	ATP-dependent peptidase activity
SDZ_RS05085	COG2911	Protein conserved in bacteria
SDZ_RS05090	COG0729	surface antigen
SDZ_RS05095	COG0505	Belongs to the CarA family
SDZ_RS05100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SDZ_RS05120	COG3409	Peptidoglycan-binding domain 1 protein
SDZ_RS05120	COG3267	Type II secretory pathway component ExeA
SDZ_RS05165	COG0492	ferredoxin-NADP+ reductase activity
SDZ_RS05170	COG0386	Belongs to the glutathione peroxidase family
SDZ_RS05225	COG1652	LysM domain
SDZ_RS05235	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SDZ_RS05240	COG1028	Short-chain dehydrogenase reductase Sdr
SDZ_RS05265	COG0497	DNA recombination
SDZ_RS05270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SDZ_RS05280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SDZ_RS05290	COG0195	Participates in both transcription termination and antitermination
SDZ_RS05295	COG0779	Required for maturation of 30S ribosomal subunits
SDZ_RS05300	COG1253	flavin adenine dinucleotide binding
SDZ_RS05305	COG1187	pseudouridine synthase activity
SDZ_RS05315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SDZ_RS05320	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SDZ_RS05325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SDZ_RS05340	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
SDZ_RS05345	COG1534	Rna-binding protein
SDZ_RS05355	COG0484	heat shock protein binding
SDZ_RS05360	COG0443	Heat shock 70 kDa protein
SDZ_RS05365	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SDZ_RS05370	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SDZ_RS05380	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SDZ_RS05385	COG1322	Protein conserved in bacteria
SDZ_RS05390	COG0440	acetolactate synthase activity
SDZ_RS05395	COG0028	Belongs to the TPP enzyme family
SDZ_RS05405	COG0440	acetolactate synthase activity
SDZ_RS05410	COG0028	Belongs to the TPP enzyme family
SDZ_RS05420	COG0277	FAD linked oxidase domain protein
SDZ_RS05420	COG0247	lactate metabolic process
SDZ_RS05475	COG1702	phosphate starvation-inducible protein PhoH
SDZ_RS05490	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SDZ_RS05540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SDZ_RS05555	COG1376	ErfK ybiS ycfS ynhG family protein
SDZ_RS05565	COG0495	leucyl-tRNA aminoacylation
SDZ_RS05580	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SDZ_RS05585	COG0799	negative regulation of ribosome biogenesis
SDZ_RS05590	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SDZ_RS05595	COG0768	penicillin binding
SDZ_RS05600	COG0772	Belongs to the SEDS family
SDZ_RS05605	COG2951	lytic endotransglycosylase activity
SDZ_RS05610	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SDZ_RS05615	COG1686	Belongs to the peptidase S11 family
SDZ_RS05620	COG2921	Belongs to the UPF0250 family
SDZ_RS05625	COG2949	membrane
SDZ_RS05630	COG0338	D12 class N6 adenine-specific DNA methyltransferase
SDZ_RS05640	COG1454	alcohol dehydrogenase
SDZ_RS05660	COG0360	Binds together with S18 to 16S ribosomal RNA
SDZ_RS05665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SDZ_RS05670	COG0557	exoribonuclease II activity
SDZ_RS05675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SDZ_RS05680	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SDZ_RS05695	COG2252	PERMEase
SDZ_RS05700	COG1309	transcriptional regulator
SDZ_RS05705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SDZ_RS05710	COG1349	DNA-binding transcription factor activity
SDZ_RS05715	COG2610	gluconate transmembrane transporter activity
SDZ_RS05720	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SDZ_RS05725	COG3395	kinase activity
SDZ_RS05730	COG0058	SHG alpha-glucan phosphorylase activity
SDZ_RS05740	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SDZ_RS05745	COG0187	DNA topoisomerase II activity
SDZ_RS05755	COG0745	RESPONSE REGULATOR receiver
SDZ_RS05765	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SDZ_RS05770	COG0494	nUDIX hydrolase
SDZ_RS05775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SDZ_RS05780	COG0180	Tryptophanyl-tRNA synthetase
SDZ_RS05785	COG0546	phosphoglycolate phosphatase activity
SDZ_RS05790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SDZ_RS05800	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SDZ_RS05805	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SDZ_RS05810	COG2211	Major facilitator Superfamily
SDZ_RS05815	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SDZ_RS05925	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SDZ_RS05935	COG1720	tRNA m6t6A37 methyltransferase activity
SDZ_RS05945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SDZ_RS05950	COG0656	L-ascorbic acid biosynthetic process
SDZ_RS05955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SDZ_RS05960	COG3395	kinase activity
SDZ_RS05975	COG5001	Diguanylate cyclase
SDZ_RS05990	COG1349	DNA-binding transcription factor activity
SDZ_RS06000	COG1830	Aldolase
SDZ_RS06010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SDZ_RS06020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SDZ_RS06025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SDZ_RS06030	COG1929	Belongs to the glycerate kinase type-1 family
SDZ_RS06065	COG1538	Outer membrane efflux protein
SDZ_RS06085	COG1484	DNA-dependent DNA replication
SDZ_RS06100	COG1297	OPT oligopeptide transporter protein
SDZ_RS06105	COG2252	PERMEase
SDZ_RS06120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SDZ_RS06120	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SDZ_RS06125	COG0517	IMP dehydrogenase activity
SDZ_RS06125	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SDZ_RS06145	COG0653	protein targeting
SDZ_RS06160	COG1053	succinate dehydrogenase
SDZ_RS06165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SDZ_RS06175	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
SDZ_RS06180	COG0469	pyruvate kinase activity
SDZ_RS06205	COG1256	bacterial-type flagellum assembly
SDZ_RS06210	COG3951	Flagellar rod assembly protein muramidase FlgJ
SDZ_RS06210	COG1705	Flagellar rod assembly protein muramidase FlgJ
SDZ_RS06220	COG1086	Polysaccharide biosynthesis protein
SDZ_RS06225	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SDZ_RS06230	COG1083	cytidylyl-transferase
SDZ_RS06250	COG0077	Prephenate dehydratase
SDZ_RS06250	COG1605	Chorismate mutase
SDZ_RS06280	COG0730	response to heat
SDZ_RS06285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SDZ_RS06290	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SDZ_RS06295	COG2027	D-alanyl-D-alanine carboxypeptidase
SDZ_RS06300	COG0436	Aminotransferase
SDZ_RS06325	COG0473	3-isopropylmalate dehydrogenase activity
SDZ_RS06345	COG2017	converts alpha-aldose to the beta-anomer
SDZ_RS06425	COG4115	mRNA cleavage
SDZ_RS06450	COG0795	lipopolysaccharide-transporting ATPase activity
SDZ_RS06465	COG1484	DNA-dependent DNA replication
SDZ_RS06470	COG1484	DNA-dependent DNA replication
SDZ_RS06490	COG0795	lipopolysaccharide-transporting ATPase activity
SDZ_RS06495	COG0470	DNA polymerase III
SDZ_RS06505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SDZ_RS06515	COG0525	valine-tRNA ligase activity
SDZ_RS06535	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SDZ_RS06540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SDZ_RS06545	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SDZ_RS06550	COG0196	riboflavin kinase activity
SDZ_RS06575	COG2207	Transcriptional regulator
SDZ_RS06630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SDZ_RS06635	COG2089	acid synthase
SDZ_RS06645	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SDZ_RS06650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SDZ_RS06655	COG1086	Polysaccharide biosynthesis protein
SDZ_RS06675	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SDZ_RS06705	COG1944	ATP diphosphatase activity
SDZ_RS06715	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SDZ_RS06725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SDZ_RS06735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SDZ_RS06740	COG1477	protein flavinylation
SDZ_RS06750	COG0442	prolyl-tRNA aminoacylation
SDZ_RS06755	COG1706	bacterial-type flagellum-dependent cell motility
SDZ_RS06760	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
SDZ_RS06770	COG4787	bacterial-type flagellum-dependent cell motility
SDZ_RS06775	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SDZ_RS06785	COG1815	bacterial-type flagellum-dependent cell motility
SDZ_RS06795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SDZ_RS06840	COG1414	Transcriptional regulator
SDZ_RS06850	COG3852	Histidine kinase
SDZ_RS06855	COG0047	phosphoribosylformylglycinamidine synthase activity
SDZ_RS06855	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SDZ_RS06900	COG3409	Peptidoglycan-binding domain 1 protein
SDZ_RS06900	COG3267	Type II secretory pathway component ExeA
SDZ_RS06955	COG0542	response to heat
SDZ_RS06970	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SDZ_RS06975	COG0564	pseudouridine synthase activity
SDZ_RS06995	COG1373	ATPase (AAA superfamily
SDZ_RS07025	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SDZ_RS07030	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SDZ_RS07045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SDZ_RS07050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SDZ_RS07055	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SDZ_RS07065	COG0157	Belongs to the NadC ModD family
SDZ_RS07070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SDZ_RS07075	COG0305	Participates in initiation and elongation during chromosome replication
SDZ_RS07095	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
SDZ_RS07100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SDZ_RS07110	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SDZ_RS07125	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SDZ_RS07140	COG0582	viral genome integration into host DNA
SDZ_RS07170	COG1388	LysM domain
SDZ_RS07170	COG4942	peptidase
SDZ_RS07175	COG1238	metal cluster binding
SDZ_RS07185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SDZ_RS07190	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
SDZ_RS07195	COG0504	CTP synthase activity
SDZ_RS07205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SDZ_RS07215	COG1381	Involved in DNA repair and RecF pathway recombination
SDZ_RS07225	COG0571	ribonuclease III activity
SDZ_RS07235	COG0481	GTPase activity
SDZ_RS07250	COG1595	DNA-templated transcription, initiation
SDZ_RS07255	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SDZ_RS07260	COG3264	Mechanosensitive ion channel
SDZ_RS07260	COG1196	nuclear chromosome segregation
SDZ_RS07280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SDZ_RS07285	COG0328	RNA-DNA hybrid ribonuclease activity
SDZ_RS07300	COG3115	cell septum assembly
SDZ_RS07310	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
SDZ_RS07330	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
SDZ_RS07335	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
SDZ_RS07355	COG1309	transcriptional regulator
SDZ_RS07360	COG0540	Belongs to the ATCase OTCase family
SDZ_RS07370	COG5001	Diguanylate cyclase
SDZ_RS07370	COG3300	MHYT domain
SDZ_RS07375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SDZ_RS07380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SDZ_RS07390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SDZ_RS07410	COG4310	Domain of unknown function (DUF2172)
SDZ_RS07420	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SDZ_RS07425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SDZ_RS07430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SDZ_RS07435	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SDZ_RS07445	COG0786	glutamate:sodium symporter activity
SDZ_RS07450	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SDZ_RS07455	COG0330	HflC and HflK could
SDZ_RS07460	COG0330	HflC and HflK could
SDZ_RS07465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SDZ_RS07470	COG1923	regulation of RNA biosynthetic process
SDZ_RS07480	COG1609	Transcriptional regulator
SDZ_RS07485	COG2814	Major facilitator Superfamily
SDZ_RS07560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SDZ_RS07570	COG0860	N-Acetylmuramoyl-L-alanine amidase
SDZ_RS07570	COG1388	LysM domain
SDZ_RS07575	COG0802	atpase or kinase
SDZ_RS07580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SDZ_RS07580	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SDZ_RS07615	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SDZ_RS07620	COG2050	protein possibly involved in aromatic compounds catabolism
SDZ_RS07655	COG2264	protein methyltransferase activity
SDZ_RS07700	COG2314	TM2 domain
SDZ_RS07725	COG0352	thiamine-phosphate diphosphorylase activity
SDZ_RS07730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SDZ_RS07755	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SDZ_RS07785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SDZ_RS07790	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SDZ_RS07795	COG0049	tRNA binding
SDZ_RS07800	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SDZ_RS07820	COG0251	oxidation-reduction process
SDZ_RS07825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SDZ_RS07860	COG0831	urea catabolic process
SDZ_RS07865	COG0832	Belongs to the urease beta subunit family
SDZ_RS07870	COG0804	urea catabolic process
SDZ_RS07880	COG0830	nickel cation binding
SDZ_RS07885	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SDZ_RS07930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SDZ_RS07955	COG1072	(Pantothenic acid kinase))
SDZ_RS07970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SDZ_RS07975	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SDZ_RS08005	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SDZ_RS08010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SDZ_RS08015	COG0281	malic enzyme
SDZ_RS08020	COG0254	rRNA binding
SDZ_RS08025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SDZ_RS08030	COG0018	arginyl-trna synthetase
SDZ_RS08045	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SDZ_RS08055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SDZ_RS08055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDZ_RS08055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SDZ_RS08070	COG2937	Belongs to the GPAT DAPAT family
SDZ_RS08080	COG0312	modulator of DNA gyrase
SDZ_RS08095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SDZ_RS08100	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SDZ_RS08105	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
SDZ_RS08110	COG3265	gluconokinase activity
SDZ_RS08115	COG0129	dihydroxy-acid dehydratase activity
SDZ_RS08120	COG0312	modulator of DNA gyrase
SDZ_RS08135	COG1792	Involved in formation and maintenance of cell shape
SDZ_RS08140	COG1077	Cell shape determining protein MreB Mrl
SDZ_RS08165	COG1414	Transcriptional regulator
SDZ_RS08170	COG1869	D-ribose catabolic process
SDZ_RS08175	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
SDZ_RS08180	COG2207	Transcriptional regulator
SDZ_RS08185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SDZ_RS08200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SDZ_RS08205	COG0629	single-stranded DNA binding
SDZ_RS08210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SDZ_RS08220	COG3028	Belongs to the UPF0307 family
SDZ_RS08230	COG2854	intermembrane phospholipid transfer
SDZ_RS08235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SDZ_RS08240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SDZ_RS08245	COG1127	ABC transporter
SDZ_RS08250	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SDZ_RS08255	COG3117	lipopolysaccharide transmembrane transporter activity
SDZ_RS08260	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
SDZ_RS08265	COG1137	ATPase activity
SDZ_RS08270	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SDZ_RS08290	COG0667	Aldo Keto reductase
SDZ_RS08305	COG1979	alcohol dehydrogenase
SDZ_RS08315	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SDZ_RS08325	COG1660	Displays ATPase and GTPase activities
SDZ_RS08335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SDZ_RS08350	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SDZ_RS08390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SDZ_RS08395	COG0552	protein localization to endoplasmic reticulum
SDZ_RS08400	COG0742	ribosomal rna small subunit methyltransferase
SDZ_RS08405	COG1760	l-serine dehydratase
SDZ_RS08410	COG0814	amino acid
SDZ_RS08415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SDZ_RS08430	COG1279	arginine transmembrane transporter activity
SDZ_RS08435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SDZ_RS08440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SDZ_RS08445	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SDZ_RS08450	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SDZ_RS08455	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SDZ_RS08465	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SDZ_RS08480	COG1475	DNA binding
SDZ_RS08485	COG1192	Involved in chromosome partitioning
SDZ_RS08490	COG0357	Ribosomal RNA small subunit methyltransferase G
SDZ_RS08495	COG0445	tRNA wobble uridine modification
SDZ_RS08510	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SDZ_RS08520	COG1328	CTP reductase activity
SDZ_RS08530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SDZ_RS08540	COG0706	membrane insertase activity
SDZ_RS08545	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SDZ_RS08550	COG0594	ribonuclease P activity
SDZ_RS08555	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SDZ_RS08560	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SDZ_RS08575	COG0187	DNA topoisomerase II activity
SDZ_RS08580	COG0751	glycine-tRNA ligase activity
SDZ_RS08585	COG0752	glycyl-tRNA synthetase alpha subunit
SDZ_RS08615	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SDZ_RS08620	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SDZ_RS08625	COG0859	PFAM glycosyl transferase family 9
SDZ_RS08630	COG3642	lipopolysaccharide core region biosynthetic process
SDZ_RS08640	COG1519	Transferase
SDZ_RS08650	COG0859	PFAM glycosyl transferase family 9
SDZ_RS08655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SDZ_RS08660	COG0705	Rhomboid family
SDZ_RS08670	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SDZ_RS08675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SDZ_RS08685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SDZ_RS08695	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SDZ_RS08710	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SDZ_RS08710	COG0316	Belongs to the HesB IscA family
SDZ_RS08720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SDZ_RS08730	COG0596	Alpha beta hydrolase
SDZ_RS08735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SDZ_RS08740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SDZ_RS08760	COG1879	ABC-type sugar transport system periplasmic component
SDZ_RS08770	COG1129	ABC transporter
SDZ_RS08775	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDZ_RS08780	COG2190	(PTS) system
SDZ_RS08790	COG3959	Transketolase, thiamine diphosphate binding domain
SDZ_RS08795	COG3958	Transketolase
SDZ_RS08800	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SDZ_RS08810	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SDZ_RS08815	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SDZ_RS08820	COG0494	nUDIX hydrolase
SDZ_RS08825	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SDZ_RS08830	COG0137	argininosuccinate synthase activity
SDZ_RS08835	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SDZ_RS08835	COG0165	Argininosuccinate lyase
SDZ_RS08845	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SDZ_RS08860	COG2885	chlorophyll binding
SDZ_RS08860	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
SDZ_RS08865	COG1879	ABC-type sugar transport system periplasmic component
SDZ_RS08880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SDZ_RS08885	COG1758	RNA polymerase activity
SDZ_RS08890	COG0194	GDP metabolic process
SDZ_RS08910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SDZ_RS08920	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SDZ_RS08935	COG1013	pyruvate-flavodoxin oxidoreductase activity
SDZ_RS08940	COG0674	pyruvate-flavodoxin oxidoreductase activity
SDZ_RS08960	COG2011	ABC-type metal ion transport system permease component
SDZ_RS08965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SDZ_RS08970	COG1464	Belongs to the NlpA lipoprotein family
SDZ_RS08980	COG2204	response regulator
SDZ_RS08985	COG3852	Histidine kinase
SDZ_RS09010	COG1295	ribonuclease BN
SDZ_RS09020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SDZ_RS09025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SDZ_RS09030	COG0006	proline dipeptidase activity
SDZ_RS09035	COG0339	signal peptide processing
SDZ_RS09055	COG1575	Belongs to the MenA family. Type 1 subfamily
SDZ_RS09070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SDZ_RS09075	COG0569	domain protein
SDZ_RS09080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SDZ_RS09080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SDZ_RS09085	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SDZ_RS09100	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SDZ_RS09105	COG0009	L-threonylcarbamoyladenylate synthase
SDZ_RS09110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SDZ_RS09115	COG0742	ribosomal rna small subunit methyltransferase
SDZ_RS09135	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SDZ_RS09140	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SDZ_RS09150	COG2091	lysine biosynthetic process via aminoadipic acid
SDZ_RS09190	COG0494	nUDIX hydrolase
SDZ_RS09195	COG0210	DNA helicase
SDZ_RS09200	COG0358	DNA primase activity
SDZ_RS09200	COG0305	Participates in initiation and elongation during chromosome replication
SDZ_RS09205	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SDZ_RS09260	COG1442	glycosyl transferase family 8
SDZ_RS09265	COG4804	nuclease activity
SDZ_RS09380	COG3409	Peptidoglycan-binding domain 1 protein
SDZ_RS09380	COG3267	Type II secretory pathway component ExeA
SDZ_RS09390	COG3620	sequence-specific DNA binding
SDZ_RS09475	COG0697	spore germination
SDZ_RS09480	COG2315	Protein conserved in bacteria
SDZ_RS09500	COG0835	chemotaxis
SDZ_RS09500	COG0784	Response regulator, receiver
SDZ_RS09615	COG0732	type I restriction modification DNA specificity domain
SDZ_RS09620	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
SDZ_RS09640	COG3541	Predicted nucleotidyltransferase
SDZ_RS09675	COG2364	Membrane
SDZ_RS09725	COG1051	belongs to the nudix hydrolase family
SDZ_RS09730	COG1393	Belongs to the ArsC family
SDZ_RS09735	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SDZ_RS09755	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SDZ_RS09805	COG4213	ABC transporter substrate-binding protein
SDZ_RS09815	COG2376	Dihydroxyacetone kinase
SDZ_RS09845	COG0800	Aldolase
SDZ_RS09850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SDZ_RS09860	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDZ_RS09880	COG0673	inositol 2-dehydrogenase activity
SDZ_RS09885	COG1609	Transcriptional regulator
SDZ_RS09900	COG1846	Transcriptional regulator
SDZ_RS09910	COG3118	belongs to the thioredoxin family
SDZ_RS09915	COG1846	Transcriptional regulator
SDZ_RS09920	COG0656	L-ascorbic acid biosynthetic process
SDZ_RS09960	COG0246	Mannitol dehydrogenase
SDZ_RS09965	COG1063	alcohol dehydrogenase
SDZ_RS09975	COG1070	Carbohydrate kinase
SDZ_RS09980	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDZ_RS09985	COG1129	ABC transporter
SDZ_RS10010	COG1609	Transcriptional regulator
SDZ_RS10015	COG2723	6-phospho-beta-galactosidase activity
SDZ_RS10030	COG4221	oxidoreductase activity
SDZ_RS10035	COG2885	chlorophyll binding
SDZ_RS10035	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
SDZ_RS10040	COG2356	endonuclease I
SDZ_RS10060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SDZ_RS10065	COG2160	L-arabinose isomerase activity
SDZ_RS10070	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDZ_RS10140	COG0733	neurotransmitter:sodium symporter activity
SDZ_RS10145	COG0716	FMN binding
SDZ_RS10165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SDZ_RS10170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SDZ_RS10175	COG1309	transcriptional regulator
SDZ_RS10195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SDZ_RS10215	COG0204	Acyl-transferase
SDZ_RS10225	COG0129	dihydroxy-acid dehydratase activity
SDZ_RS10280	COG0367	asparagine synthase
SDZ_RS10285	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SDZ_RS10305	COG0174	glutamine synthetase
SDZ_RS10310	COG0070	glutamate synthase
SDZ_RS10310	COG0067	glutamate synthase
SDZ_RS10310	COG0069	glutamate synthase activity
SDZ_RS10335	COG1464	Belongs to the NlpA lipoprotein family
SDZ_RS10340	COG3071	HemY protein
SDZ_RS10350	COG3072	Adenylate cyclase
SDZ_RS10360	COG0019	diaminopimelate decarboxylase activity
SDZ_RS10365	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SDZ_RS10385	COG2197	response regulator
SDZ_RS10435	COG0210	DNA helicase
SDZ_RS10440	COG0346	lactoylglutathione lyase activity
SDZ_RS10475	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SDZ_RS10475	COG3008	intermembrane lipid transfer
SDZ_RS10480	COG2995	paraquat-inducible protein a
SDZ_RS10495	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SDZ_RS10505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDZ_RS10505	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SDZ_RS10530	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SDZ_RS10535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SDZ_RS10540	COG0215	cysteine-tRNA ligase activity
SDZ_RS10545	COG3593	DNA synthesis involved in DNA repair
SDZ_RS10550	COG1561	YicC-like family, N-terminal region
SDZ_RS10555	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SDZ_RS10560	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SDZ_RS10570	COG0051	transcription antitermination factor activity, RNA binding
SDZ_RS10575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SDZ_RS10585	COG0089	rRNA binding
SDZ_RS10590	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SDZ_RS10595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SDZ_RS10600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SDZ_RS10605	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SDZ_RS10610	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SDZ_RS10615	COG0255	Belongs to the universal ribosomal protein uL29 family
SDZ_RS10620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SDZ_RS10625	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SDZ_RS10630	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SDZ_RS10635	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SDZ_RS10640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SDZ_RS10645	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SDZ_RS10650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SDZ_RS10655	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SDZ_RS10660	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SDZ_RS10665	COG1841	ribosomal large subunit assembly
SDZ_RS10675	COG0201	protein transport
SDZ_RS10680	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SDZ_RS10685	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SDZ_RS10690	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SDZ_RS10695	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SDZ_RS10740	COG0583	DNA-binding transcription factor activity
SDZ_RS10755	COG0110	maltose O-acetyltransferase activity
SDZ_RS10765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SDZ_RS10780	COG0762	integral membrane protein
SDZ_RS10785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SDZ_RS10805	COG0010	Belongs to the arginase family
SDZ_RS10815	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SDZ_RS10825	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SDZ_RS10830	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SDZ_RS10835	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SDZ_RS10840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SDZ_RS10885	COG1002	Type II restriction enzyme, methylase subunits
SDZ_RS10905	COG4783	chaperone-mediated protein folding
SDZ_RS10920	COG0671	phosphoesterase, PA-phosphatase related
SDZ_RS10930	COG3083	sulfuric ester hydrolase activity
SDZ_RS10955	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SDZ_RS10960	COG0343	queuine tRNA-ribosyltransferase activity
SDZ_RS10965	COG1115	amino acid carrier protein
SDZ_RS10970	COG2040	homocysteine
SDZ_RS10995	COG1862	Preprotein translocase
SDZ_RS11000	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SDZ_RS11005	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SDZ_RS11015	COG0640	Transcriptional regulator
SDZ_RS11020	COG1104	cysteine desulfurase activity
SDZ_RS11025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SDZ_RS11030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SDZ_RS11040	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SDZ_RS11050	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SDZ_RS11060	COG2976	Protein conserved in bacteria
SDZ_RS11065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SDZ_RS11115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SDZ_RS11135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SDZ_RS11140	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SDZ_RS11145	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SDZ_RS11165	COG0301	tRNA thio-modification
SDZ_RS11165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SDZ_RS11185	COG4591	ABC-type transport system involved in lipoprotein release permease component
SDZ_RS11190	COG1136	(ABC) transporter
SDZ_RS11195	COG4591	ABC-type transport system involved in lipoprotein release permease component
SDZ_RS11205	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SDZ_RS11215	COG1722	exodeoxyribonuclease VII activity
SDZ_RS11220	COG0142	geranyltranstransferase activity
SDZ_RS11225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SDZ_RS11230	COG1666	GTP binding
SDZ_RS11235	COG2814	Major facilitator Superfamily
SDZ_RS11340	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
SDZ_RS11345	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
SDZ_RS11350	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
SDZ_RS11355	COG2871	sodium ion transport
SDZ_RS11440	COG0052	Belongs to the universal ribosomal protein uS2 family
SDZ_RS11445	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SDZ_RS11455	COG0233	cytoplasmic translational termination
SDZ_RS11460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SDZ_RS11465	COG0575	Belongs to the CDS family
SDZ_RS11470	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SDZ_RS11475	COG0750	zinc metalloprotease
SDZ_RS11490	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SDZ_RS11495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SDZ_RS11500	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SDZ_RS11505	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SDZ_RS11515	COG0825	malonyl-CoA metabolic process
SDZ_RS11530	COG1879	ABC-type sugar transport system periplasmic component
SDZ_RS11535	COG1879	ABC-type sugar transport system periplasmic component
SDZ_RS11550	COG2873	o-acetylhomoserine
SDZ_RS11560	COG1368	sulfuric ester hydrolase activity
SDZ_RS11605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SDZ_RS11615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SDZ_RS11625	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SDZ_RS11665	COG0800	Aldolase
SDZ_RS11670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SDZ_RS11675	COG2721	sulfolactate sulfo-lyase activity
SDZ_RS11680	COG0246	Mannitol dehydrogenase
SDZ_RS11685	COG1063	alcohol dehydrogenase
SDZ_RS11700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SDZ_RS11725	COG1733	regulation of RNA biosynthetic process
SDZ_RS11745	COG1484	DNA-dependent DNA replication
SDZ_RS11775	COG1082	Xylose isomerase domain protein TIM barrel
SDZ_RS11790	COG1172	Belongs to the binding-protein-dependent transport system permease family
SDZ_RS11795	COG1737	Transcriptional regulator
SDZ_RS11815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SDZ_RS11820	COG0800	Aldolase
SDZ_RS11840	COG1904	glucuronate isomerase
SDZ_RS11845	COG1312	Catalyzes the dehydration of D-mannonate
SDZ_RS11850	COG0246	Mannitol dehydrogenase
SDZ_RS11860	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SDZ_RS11865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SDZ_RS11880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SDZ_RS11890	COG2969	positive regulation of protein catabolic process
SDZ_RS11935	COG2223	nitrite transmembrane transporter activity
SDZ_RS11940	COG2207	Transcriptional regulator
SDZ_RS11955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SDZ_RS11960	COG2358	TRAP transporter, solute receptor (TAXI family
SDZ_RS11965	COG2001	Belongs to the MraZ family
SDZ_RS11970	COG0275	rRNA processing
SDZ_RS11980	COG0768	penicillin binding
SDZ_RS11985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SDZ_RS11990	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SDZ_RS11995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SDZ_RS12000	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SDZ_RS12005	COG0772	Belongs to the SEDS family
SDZ_RS12010	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SDZ_RS12015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SDZ_RS12020	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SDZ_RS12025	COG0849	cell division
SDZ_RS12030	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SDZ_RS12050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SDZ_RS12055	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SDZ_RS12060	COG3023	N-Acetylmuramoyl-L-alanine amidase
SDZ_RS12070	COG0039	L-malate dehydrogenase activity
SDZ_RS12080	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
SDZ_RS12085	COG0840	transmembrane signaling receptor activity
SDZ_RS12090	COG0534	Mate efflux family protein
SDZ_RS12095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SDZ_RS12105	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SDZ_RS12110	COG2011	ABC-type metal ion transport system permease component
SDZ_RS12115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SDZ_RS12130	COG0228	four-way junction DNA binding
SDZ_RS12140	COG0336	Belongs to the RNA methyltransferase TrmD family
SDZ_RS12145	COG0335	large ribosomal subunit rRNA binding
SDZ_RS12165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SDZ_RS12220	COG1051	belongs to the nudix hydrolase family
SDZ_RS12230	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SDZ_RS12235	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
SDZ_RS12240	COG0513	Belongs to the DEAD box helicase family
SDZ_RS12245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SDZ_RS12250	COG1737	Transcriptional regulator
SDZ_RS12255	COG0656	L-ascorbic acid biosynthetic process
SDZ_RS12275	COG1979	alcohol dehydrogenase
SDZ_RS12280	COG1028	Short-chain dehydrogenase reductase Sdr
SDZ_RS12295	COG0583	DNA-binding transcription factor activity
SDZ_RS12300	COG0656	L-ascorbic acid biosynthetic process
SDZ_RS12305	COG0656	L-ascorbic acid biosynthetic process
SDZ_RS12315	COG0297	glycogen (starch) synthase activity
SDZ_RS12320	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SDZ_RS12330	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SDZ_RS12335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SDZ_RS12365	COG2813	Specifically methylates the guanine in position
SDZ_RS12370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SDZ_RS12375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SDZ_RS12380	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
SDZ_RS12390	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
SDZ_RS12405	COG4974	Belongs to the 'phage' integrase family
SDZ_RS12425	COG0545	Peptidyl-prolyl cis-trans isomerase
SDZ_RS12430	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SDZ_RS12435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SDZ_RS12450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SDZ_RS12450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SDZ_RS12455	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SDZ_RS12470	COG0583	DNA-binding transcription factor activity
SDZ_RS12505	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SDZ_RS12515	COG0439	Biotin carboxylase
SDZ_RS12520	COG4232	protein-disulfide reductase activity
SDZ_RS12570	COG0840	transmembrane signaling receptor activity
SDZ_RS12590	COG0629	single-stranded DNA binding
SDZ_RS12595	COG0534	Mate efflux family protein
SDZ_RS12600	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SDZ_RS12620	COG0789	Transcriptional regulator
SDZ_RS12630	COG1979	alcohol dehydrogenase
SDZ_RS12640	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SDZ_RS12650	COG0840	transmembrane signaling receptor activity
SDZ_RS12655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDZ_RS12675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDZ_RS12685	COG1733	regulation of RNA biosynthetic process
SDZ_RS12690	COG1979	alcohol dehydrogenase
SDZ_RS12695	COG2249	NAD(P)H dehydrogenase (quinone) activity
SDZ_RS12705	COG0488	(ABC) transporter
SDZ_RS12715	COG3527	Alpha-acetolactate decarboxylase
SDZ_RS12720	COG0840	transmembrane signaling receptor activity
SDZ_RS12725	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SDZ_RS12730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SDZ_RS12735	COG0659	secondary active sulfate transmembrane transporter activity
SDZ_RS12745	COG0582	viral genome integration into host DNA
SDZ_RS12935	COG0740	serine-type endopeptidase activity
SDZ_RS13165	COG2770	Histidine kinase
SDZ_RS13165	COG2208	phosphoserine phosphatase activity
SDZ_RS13170	COG0425	Belongs to the sulfur carrier protein TusA family
SDZ_RS13180	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SDZ_RS13195	COG0560	Phosphoserine phosphatase
SDZ_RS13200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SDZ_RS13205	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
SDZ_RS13210	COG0561	phosphatase activity
SDZ_RS13215	COG4178	(ABC) transporter
SDZ_RS13225	COG0739	heme binding
SDZ_RS13240	COG0151	Belongs to the GarS family
SDZ_RS13245	COG0138	bifunctional purine biosynthesis protein purh
SDZ_RS13250	COG0776	regulation of translation
SDZ_RS13255	COG0033	Phosphoglucomutase
SDZ_RS13265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDZ_RS13275	COG1115	amino acid carrier protein
SDZ_RS13280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SDZ_RS13280	COG2199	diguanylate cyclase activity
SDZ_RS13285	COG0586	Pfam SNARE associated Golgi protein
SDZ_RS13290	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SDZ_RS13295	COG1674	ftsk spoiiie
SDZ_RS13305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SDZ_RS13310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SDZ_RS13315	COG1286	toxin biosynthetic process
SDZ_RS13350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SDZ_RS13360	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SDZ_RS13365	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SDZ_RS13385	COG4794	Type iii secretion
SDZ_RS13400	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SDZ_RS13405	COG1366	Belongs to the anti-sigma-factor antagonist family
SDZ_RS13415	COG2770	Histidine kinase
SDZ_RS13415	COG2208	phosphoserine phosphatase activity
SDZ_RS13435	COG4792	protein secretion
SDZ_RS13485	COG1450	Type ii and iii secretion system protein
SDZ_RS13515	COG0786	glutamate:sodium symporter activity
SDZ_RS13525	COG0433	COG0433 Predicted ATPase
SDZ_RS13530	COG4669	(LipO)protein
SDZ_RS13550	COG0741	lytic transglycosylase activity
SDZ_RS13555	COG1366	Belongs to the anti-sigma-factor antagonist family
SDZ_RS13590	COG3267	Type II secretory pathway component ExeA
SDZ_RS13590	COG3409	Peptidoglycan-binding domain 1 protein
SDZ_RS13615	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SDZ_RS13620	COG4790	Type iii secretion
SDZ_RS13625	COG0372	Belongs to the citrate synthase family
SDZ_RS13630	COG0788	formyltetrahydrofolate deformylase activity
SDZ_RS13650	COG0366	Alpha amylase catalytic
SDZ_RS13655	COG2195	Cleaves the N-terminal amino acid of tripeptides
SDZ_RS13660	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SDZ_RS13670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SDZ_RS13675	COG0589	response to stress
SDZ_RS13695	COG0728	peptidoglycan biosynthetic process
SDZ_RS13705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SDZ_RS13730	COG2853	Lipoprotein
SDZ_RS13735	COG0287	Prephenate dehydrogenase
SDZ_RS13735	COG1605	Chorismate mutase
SDZ_RS13745	COG0501	Belongs to the peptidase M48B family
SDZ_RS13750	COG2089	acid synthase
SDZ_RS13760	COG4213	ABC transporter substrate-binding protein
SDZ_RS13770	COG0840	transmembrane signaling receptor activity
SDZ_RS13775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SDZ_RS13780	COG1640	4-alpha-glucanotransferase
SDZ_RS13785	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SDZ_RS13795	COG0616	signal peptide processing
SDZ_RS13820	COG0519	Catalyzes the synthesis of GMP from XMP
SDZ_RS13820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SDZ_RS13835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SDZ_RS13845	COG0778	Nitroreductase
SDZ_RS13890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SDZ_RS13895	COG0675	Transposase, IS605 OrfB family
SDZ_RS13900	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SDZ_RS13905	COG0217	transcriptional regulatory protein
SDZ_RS13920	COG0471	metal ion transport
SDZ_RS13925	COG0583	DNA-binding transcription factor activity
SDZ_RS13935	COG0837	glucose binding
SDZ_RS13965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SDZ_RS13970	COG2011	ABC-type metal ion transport system permease component
SDZ_RS13980	COG1464	Belongs to the NlpA lipoprotein family
SDZ_RS14020	COG0205	6-phosphofructokinase activity
SDZ_RS14025	COG0149	triose-phosphate isomerase activity
SDZ_RS14040	COG0083	homoserine kinase activity
SDZ_RS14045	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SDZ_RS14050	COG0675	Transposase, IS605 OrfB family
SDZ_RS14060	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
SDZ_RS14065	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SDZ_RS14065	COG1918	ferrous iron import across plasma membrane
SDZ_RS14080	COG2217	Heavy metal translocating P-type atpase
SDZ_RS14100	COG1484	DNA-dependent DNA replication
SDZ_RS14125	COG1522	sequence-specific DNA binding
SDZ_RS14155	COG3706	GGDEF domain
SDZ_RS14160	COG2203	Gaf domain
SDZ_RS14160	COG2199	diguanylate cyclase activity
SDZ_RS14175	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SDZ_RS14190	COG2223	nitrite transmembrane transporter activity
SDZ_RS14205	COG4974	Belongs to the 'phage' integrase family
SDZ_RS14210	COG0582	viral genome integration into host DNA
SDZ_RS14275	COG0133	tryptophan synthase activity
SDZ_RS14280	COG0134	indole-3-glycerol-phosphate synthase activity
SDZ_RS14280	COG0135	phosphoribosylanthranilate isomerase activity
SDZ_RS14285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SDZ_RS14310	COG0675	Transposase, IS605 OrfB family
SDZ_RS14315	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SDZ_RS14320	COG0512	Glutamine amidotransferase of anthranilate synthase
SDZ_RS14325	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SDZ_RS14390	COG1971	Probably functions as a manganese efflux pump
SDZ_RS14395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SDZ_RS14400	COG0572	uridine kinase
SDZ_RS14415	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
SDZ_RS14440	COG2207	Transcriptional regulator
SDZ_RS14445	COG2211	Major facilitator Superfamily
SDZ_RS14450	COG0366	Alpha amylase catalytic
SDZ_RS14455	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SDZ_RS14460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SDZ_RS14460	COG0116	Belongs to the methyltransferase superfamily
SDZ_RS14470	COG0613	PHP domain protein
SDZ_RS14480	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SDZ_RS14485	COG0590	tRNA wobble adenosine to inosine editing
SDZ_RS14495	COG0009	L-threonylcarbamoyladenylate synthase
SDZ_RS14510	COG2502	aspartate--ammonia ligase
SDZ_RS14520	COG5001	Diguanylate cyclase
SDZ_RS14535	COG2974	May be involved in recombination
SDZ_RS14550	COG0318	PFAM AMP-dependent synthetase and ligase
SDZ_RS14590	COG2249	NAD(P)H dehydrogenase (quinone) activity
SDZ_RS14615	COG1757	Na H antiporter
SDZ_RS14620	COG0675	Transposase, IS605 OrfB family
SDZ_RS14645	COG1373	ATPase (AAA superfamily
SDZ_RS14655	COG1177	transmembrane transport
SDZ_RS14660	COG1176	ABC-type spermidine putrescine transport system, permease component I
SDZ_RS14665	COG3842	ATPase activity
SDZ_RS14670	COG1979	alcohol dehydrogenase
SDZ_RS14680	COG0739	heme binding
SDZ_RS14685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SDZ_RS14695	COG0656	L-ascorbic acid biosynthetic process
SDZ_RS14710	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SDZ_RS14715	COG2996	Protein conserved in bacteria
SDZ_RS14720	COG0616	signal peptide processing
SDZ_RS14725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SDZ_RS14730	COG0840	transmembrane signaling receptor activity
SDZ_RS14745	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SDZ_RS14750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SDZ_RS14780	COG0675	Transposase, IS605 OrfB family
SDZ_RS14805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SDZ_RS14810	COG1028	Short-chain dehydrogenase reductase Sdr
SDZ_RS14820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SDZ_RS14860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SDZ_RS14870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SDZ_RS14875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SDZ_RS14915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SDZ_RS14960	COG0675	Transposase, IS605 OrfB family
SDZ_RS14995	COG1749	Flagellar hook protein flgE
SDZ_RS15000	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SDZ_RS15025	COG4660	Part of a membrane complex involved in electron transport
SDZ_RS15030	COG4659	FMN binding
SDZ_RS15035	COG4658	electron transport chain
SDZ_RS15040	COG4656	Part of a membrane complex involved in electron transport
SDZ_RS15045	COG2878	Part of a membrane complex involved in electron transport
SDZ_RS15050	COG4657	Part of a membrane complex involved in electron transport
SDZ_RS15055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SDZ_RS15065	COG2194	sulfuric ester hydrolase activity
SDZ_RS15090	COG0084	hydrolase, TatD family'
SDZ_RS15120	COG1132	(ABC) transporter
SDZ_RS15205	COG1484	DNA-dependent DNA replication
SDZ_RS15260	COG1442	glycosyl transferase family 8
SDZ_RS15265	COG1215	transferase activity, transferring glycosyl groups
SDZ_RS15335	COG1484	DNA-dependent DNA replication