locus-tag	class	description
AWJ20_1	COG2814	Major facilitator Superfamily
AWJ20_1002	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
AWJ20_1014	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AWJ20_1019	COG0352	thiamine-phosphate diphosphorylase activity
AWJ20_1019	COG0351	phosphomethylpyrimidine kinase
AWJ20_1024	COG0318	PFAM AMP-dependent synthetase and ligase
AWJ20_1027	COG2272	Belongs to the type-B carboxylesterase lipase family
AWJ20_1042	COG0210	DNA helicase
AWJ20_1045	COG0656	L-ascorbic acid biosynthetic process
AWJ20_1046	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AWJ20_1060	COG0058	SHG alpha-glucan phosphorylase activity
AWJ20_1063	COG0459	protein refolding
AWJ20_1065	COG0431	NADPH-dependent FMN reductase
AWJ20_107	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWJ20_1075	COG2814	Major facilitator Superfamily
AWJ20_1076	COG0517	IMP dehydrogenase activity
AWJ20_1076	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AWJ20_1088	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWJ20_1091	COG0180	Tryptophanyl-tRNA synthetase
AWJ20_1101	COG0509	glycine decarboxylation via glycine cleavage system
AWJ20_1106	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AWJ20_1108	COG0667	Aldo Keto reductase
AWJ20_1116	COG3485	protocatechuate 3,4-dioxygenase
AWJ20_1127	COG0084	hydrolase, TatD family'
AWJ20_1139	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_114	COG0109	protoheme IX farnesyltransferase activity
AWJ20_1140	COG0183	Belongs to the thiolase family
AWJ20_1141	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AWJ20_1146	COG0673	inositol 2-dehydrogenase activity
AWJ20_1147	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AWJ20_1149	COG1113	amino acid transport
AWJ20_115	COG1960	acyl-CoA dehydrogenase activity
AWJ20_1160	COG0343	queuine tRNA-ribosyltransferase activity
AWJ20_1164	COG1999	signal sequence binding
AWJ20_1173	COG0756	dUTP diphosphatase activity
AWJ20_1177	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWJ20_1186	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AWJ20_1191	COG2313	pseudouridylate synthase activity
AWJ20_1205	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AWJ20_1208	COG0418	dihydroorotase activity
AWJ20_1214	COG1902	pentaerythritol trinitrate reductase activity
AWJ20_1228	COG0833	amino acid
AWJ20_1233	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AWJ20_1253	COG0604	alcohol dehydrogenase
AWJ20_1253	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_1253	COG3321	synthase
AWJ20_1265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AWJ20_1268	COG0436	Aminotransferase
AWJ20_1275	COG1132	(ABC) transporter
AWJ20_1278	COG0666	response to abiotic stimulus
AWJ20_1280	COG0481	GTPase activity
AWJ20_1282	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AWJ20_1283	COG0484	heat shock protein binding
AWJ20_1291	COG2815	serine threonine protein kinase
AWJ20_1291	COG0515	serine threonine protein kinase
AWJ20_1294	COG0588	phosphoglycerate mutase activity
AWJ20_1301	COG0513	Belongs to the DEAD box helicase family
AWJ20_1305	COG0483	inositol monophosphate 1-phosphatase activity
AWJ20_1307	COG0156	8-amino-7-oxononanoate synthase activity
AWJ20_131	COG0004	ammonium transporteR
AWJ20_1310	COG0156	8-amino-7-oxononanoate synthase activity
AWJ20_1319	COG0488	(ABC) transporter
AWJ20_1320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWJ20_1322	COG0037	tRNA processing
AWJ20_1346	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AWJ20_1349	COG0612	Peptidase, M16
AWJ20_1354	COG2271	Major facilitator Superfamily
AWJ20_1355	COG0673	inositol 2-dehydrogenase activity
AWJ20_1356	COG0823	Involved in the tonB-independent uptake of proteins
AWJ20_1361	COG2017	converts alpha-aldose to the beta-anomer
AWJ20_1371	COG0604	alcohol dehydrogenase
AWJ20_1371	COG3321	synthase
AWJ20_1371	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_1374	COG1472	Belongs to the glycosyl hydrolase 3 family
AWJ20_1375	COG2814	Major facilitator Superfamily
AWJ20_1383	COG0515	serine threonine protein kinase
AWJ20_1392	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWJ20_1394	COG2267	carboxylic ester hydrolase activity
AWJ20_1411	COG0529	Catalyzes the synthesis of activated sulfate
AWJ20_1418	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AWJ20_1426	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AWJ20_1431	COG0052	Belongs to the universal ribosomal protein uS2 family
AWJ20_1444	COG2175	clavaminate synthase activity
AWJ20_1451	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AWJ20_1452	COG0513	Belongs to the DEAD box helicase family
AWJ20_1468	COG4589	Belongs to the CDS family
AWJ20_1472	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AWJ20_1499	COG0617	tRNA 3'-terminal CCA addition
AWJ20_1502	COG0667	Aldo Keto reductase
AWJ20_1503	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWJ20_1505	COG1584	GPR1 FUN34 yaaH family protein
AWJ20_1506	COG2271	Major facilitator Superfamily
AWJ20_1513	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AWJ20_1517	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AWJ20_1523	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AWJ20_1535	COG0557	exoribonuclease II activity
AWJ20_1536	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AWJ20_1538	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AWJ20_1545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AWJ20_1546	COG0473	3-isopropylmalate dehydrogenase activity
AWJ20_1552	COG4221	oxidoreductase activity
AWJ20_1555	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AWJ20_1574	COG0656	L-ascorbic acid biosynthetic process
AWJ20_1576	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWJ20_158	COG2175	clavaminate synthase activity
AWJ20_1582	COG0459	protein refolding
AWJ20_1586	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AWJ20_1596	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AWJ20_1597	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AWJ20_16	COG0823	Involved in the tonB-independent uptake of proteins
AWJ20_16	COG1506	peptidase
AWJ20_160	COG1741	Belongs to the pirin family
AWJ20_1607	COG0513	Belongs to the DEAD box helicase family
AWJ20_161	COG2814	Major facilitator Superfamily
AWJ20_1616	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWJ20_1616	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWJ20_1619	COG0004	ammonium transporteR
AWJ20_1627	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_1628	COG3961	Belongs to the TPP enzyme family
AWJ20_163	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_1635	COG0515	serine threonine protein kinase
AWJ20_1635	COG2815	serine threonine protein kinase
AWJ20_1637	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AWJ20_164	COG0736	holo-[acyl-carrier-protein] synthase activity
AWJ20_1645	COG0424	maF-like protein
AWJ20_1652	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWJ20_1653	COG1196	nuclear chromosome segregation
AWJ20_166	COG1061	Type III restriction enzyme res subunit
AWJ20_1660	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AWJ20_1666	COG0515	serine threonine protein kinase
AWJ20_167	COG0598	Magnesium transport protein CorA
AWJ20_1673	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AWJ20_1677	COG0459	protein refolding
AWJ20_1681	COG2814	Major facilitator Superfamily
AWJ20_1683	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AWJ20_1690	COG0515	serine threonine protein kinase
AWJ20_1690	COG2815	serine threonine protein kinase
AWJ20_1692	COG0515	serine threonine protein kinase
AWJ20_1692	COG2815	serine threonine protein kinase
AWJ20_171	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AWJ20_1713	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AWJ20_1714	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AWJ20_1716	COG0596	Alpha beta hydrolase
AWJ20_1717	COG1022	Amp-dependent synthetase and ligase
AWJ20_1720	COG0489	protein tyrosine kinase activity
AWJ20_1722	COG0386	Belongs to the glutathione peroxidase family
AWJ20_1732	COG0515	serine threonine protein kinase
AWJ20_1732	COG2815	serine threonine protein kinase
AWJ20_1733	COG0495	leucyl-tRNA aminoacylation
AWJ20_1736	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWJ20_175	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AWJ20_1756	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWJ20_1757	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWJ20_1757	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AWJ20_1758	COG1012	belongs to the aldehyde dehydrogenase family
AWJ20_1762	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWJ20_1766	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AWJ20_177	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_178	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_178	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_1780	COG0215	cysteine-tRNA ligase activity
AWJ20_1795	COG2814	Major facilitator Superfamily
AWJ20_180	COG0028	Belongs to the TPP enzyme family
AWJ20_1812	COG4284	Utp--glucose-1-phosphate uridylyltransferase
AWJ20_1819	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AWJ20_182	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AWJ20_1825	COG0022	dehydrogenase e1 component
AWJ20_1830	COG0251	oxidation-reduction process
AWJ20_1831	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AWJ20_184	COG0519	Catalyzes the synthesis of GMP from XMP
AWJ20_184	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AWJ20_1840	COG1253	flavin adenine dinucleotide binding
AWJ20_1858	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWJ20_1867	COG0515	serine threonine protein kinase
AWJ20_1867	COG2815	serine threonine protein kinase
AWJ20_1868	COG0131	Imidazoleglycerol-phosphate dehydratase
AWJ20_187	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWJ20_1871	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_1883	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AWJ20_1884	COG1012	belongs to the aldehyde dehydrogenase family
AWJ20_1885	COG0316	Belongs to the HesB IscA family
AWJ20_1891	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AWJ20_1897	COG0484	heat shock protein binding
AWJ20_1915	COG0625	glutathione transferase activity
AWJ20_1916	COG1012	belongs to the aldehyde dehydrogenase family
AWJ20_1922	COG0339	signal peptide processing
AWJ20_193	COG2271	Major facilitator Superfamily
AWJ20_1932	COG3250	beta-galactosidase activity
AWJ20_1937	COG1012	belongs to the aldehyde dehydrogenase family
AWJ20_1941	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWJ20_1948	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AWJ20_1949	COG0436	Aminotransferase
AWJ20_1954	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AWJ20_1957	COG0473	3-isopropylmalate dehydrogenase activity
AWJ20_1960	COG0006	proline dipeptidase activity
AWJ20_1964	COG1956	GAF domain-containing protein
AWJ20_1966	COG3250	beta-galactosidase activity
AWJ20_1967	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWJ20_1968	COG0724	RNA recognition motif
AWJ20_1969	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_1974	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AWJ20_1976	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_1980	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWJ20_1985	COG1196	nuclear chromosome segregation
AWJ20_1986	COG2226	methyltransferase
AWJ20_1998	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWJ20_2	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AWJ20_2012	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AWJ20_2013	COG0135	phosphoribosylanthranilate isomerase activity
AWJ20_2014	COG0009	L-threonylcarbamoyladenylate synthase
AWJ20_2015	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWJ20_2017	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWJ20_2025	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AWJ20_2033	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWJ20_2035	COG0515	serine threonine protein kinase
AWJ20_2035	COG2815	serine threonine protein kinase
AWJ20_2037	COG0443	Heat shock 70 kDa protein
AWJ20_2038	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWJ20_204	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWJ20_2041	COG1119	ATPase activity
AWJ20_2047	COG2814	Major facilitator Superfamily
AWJ20_2053	COG0228	four-way junction DNA binding
AWJ20_2071	COG0133	tryptophan synthase activity
AWJ20_2078	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWJ20_2079	COG1196	nuclear chromosome segregation
AWJ20_2084	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AWJ20_2088	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AWJ20_2093	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AWJ20_2094	COG2814	Major facilitator Superfamily
AWJ20_2103	COG0724	RNA recognition motif
AWJ20_2104	COG0484	heat shock protein binding
AWJ20_2105	COG0473	3-isopropylmalate dehydrogenase activity
AWJ20_2105	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AWJ20_2106	COG2233	PERMEase
AWJ20_2108	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWJ20_2115	COG4286	Uncharacterised protein family (UPF0160)
AWJ20_2120	COG0017	Asparaginyl-tRNA synthetase
AWJ20_2126	COG0726	polysaccharide deacetylase
AWJ20_213	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWJ20_2134	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWJ20_2135	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AWJ20_2140	COG1362	aminopeptidase activity
AWJ20_2147	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AWJ20_2148	COG2814	Major facilitator Superfamily
AWJ20_2151	COG0488	(ABC) transporter
AWJ20_2153	COG2815	serine threonine protein kinase
AWJ20_2153	COG0515	serine threonine protein kinase
AWJ20_2171	COG2814	Major facilitator Superfamily
AWJ20_2173	COG1022	Amp-dependent synthetase and ligase
AWJ20_2176	COG0833	amino acid
AWJ20_2182	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AWJ20_2183	COG2814	Major facilitator Superfamily
AWJ20_2185	COG0384	phenazine biosynthesis protein PhzF
AWJ20_2186	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AWJ20_2192	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWJ20_2199	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWJ20_22	COG0477	Major facilitator Superfamily
AWJ20_2204	COG2175	clavaminate synthase activity
AWJ20_2221	COG0505	Belongs to the CarA family
AWJ20_2222	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWJ20_2227	COG2267	carboxylic ester hydrolase activity
AWJ20_2228	COG4221	oxidoreductase activity
AWJ20_2242	COG2272	Belongs to the type-B carboxylesterase lipase family
AWJ20_2260	COG2815	serine threonine protein kinase
AWJ20_2260	COG0515	serine threonine protein kinase
AWJ20_2264	COG0513	Belongs to the DEAD box helicase family
AWJ20_2273	COG0154	amidase activity
AWJ20_2281	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AWJ20_229	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AWJ20_2290	COG0833	amino acid
AWJ20_2293	COG1132	(ABC) transporter
AWJ20_2295	COG0473	3-isopropylmalate dehydrogenase activity
AWJ20_2299	COG2124	cytochrome p450
AWJ20_2299	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWJ20_2300	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AWJ20_2301	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AWJ20_2303	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AWJ20_2308	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_2309	COG0698	ribose 5-phosphate isomerase
AWJ20_2311	COG0149	triose-phosphate isomerase activity
AWJ20_2316	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWJ20_2320	COG0515	serine threonine protein kinase
AWJ20_2320	COG2815	serine threonine protein kinase
AWJ20_2324	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AWJ20_2327	COG0436	Aminotransferase
AWJ20_2330	COG0656	L-ascorbic acid biosynthetic process
AWJ20_2335	COG0154	amidase activity
AWJ20_2341	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AWJ20_2345	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWJ20_2350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AWJ20_2354	COG0484	heat shock protein binding
AWJ20_2360	COG0183	Belongs to the thiolase family
AWJ20_2368	COG1404	Belongs to the peptidase S8 family
AWJ20_2368	COG4935	Belongs to the peptidase S8 family
AWJ20_2382	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_2383	COG1741	Belongs to the pirin family
AWJ20_239	COG0183	Belongs to the thiolase family
AWJ20_2398	COG2124	cytochrome p450
AWJ20_24	COG0318	PFAM AMP-dependent synthetase and ligase
AWJ20_2402	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWJ20_2408	COG3118	belongs to the thioredoxin family
AWJ20_242	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AWJ20_2420	COG2124	cytochrome p450
AWJ20_2422	COG1716	ATPase activity
AWJ20_2422	COG1131	(ABC) transporter
AWJ20_2422	COG0842	Transport permease protein
AWJ20_2423	COG1132	(ABC) transporter
AWJ20_2429	COG0156	8-amino-7-oxononanoate synthase activity
AWJ20_2431	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AWJ20_2437	COG1063	alcohol dehydrogenase
AWJ20_2438	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AWJ20_2439	COG0477	Major facilitator Superfamily
AWJ20_245	COG1034	ATP synthesis coupled electron transport
AWJ20_2450	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AWJ20_2451	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AWJ20_2452	COG0445	tRNA wobble uridine modification
AWJ20_2454	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AWJ20_2455	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AWJ20_2458	COG2175	clavaminate synthase activity
AWJ20_2459	COG0154	amidase activity
AWJ20_246	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_2461	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWJ20_2469	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AWJ20_2472	COG1446	asparaginase
AWJ20_2473	COG0515	serine threonine protein kinase
AWJ20_2478	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWJ20_2487	COG0706	membrane insertase activity
AWJ20_2491	COG0083	homoserine kinase activity
AWJ20_2492	COG0612	Peptidase, M16
AWJ20_2494	COG0179	Fumarylacetoacetate (FAA) hydrolase
AWJ20_2498	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AWJ20_2499	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AWJ20_252	COG2814	Major facilitator Superfamily
AWJ20_2520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AWJ20_2521	COG0469	pyruvate kinase activity
AWJ20_2524	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AWJ20_2528	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AWJ20_2529	COG0484	heat shock protein binding
AWJ20_2532	COG0667	Aldo Keto reductase
AWJ20_2540	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWJ20_2549	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AWJ20_255	COG0571	ribonuclease III activity
AWJ20_2559	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AWJ20_2567	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWJ20_257	COG0590	tRNA wobble adenosine to inosine editing
AWJ20_2575	COG0515	serine threonine protein kinase
AWJ20_2576	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWJ20_2582	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AWJ20_2585	COG2814	Major facilitator Superfamily
AWJ20_2591	COG0248	Ppx GppA phosphatase
AWJ20_2592	COG0833	amino acid
AWJ20_2593	COG2814	Major facilitator Superfamily
AWJ20_2594	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWJ20_2599	COG1902	pentaerythritol trinitrate reductase activity
AWJ20_26	COG0285	dihydrofolate synthase activity
AWJ20_2602	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWJ20_2635	COG0678	peroxiredoxin activity
AWJ20_2658	COG1643	Atp-dependent helicase
AWJ20_266	COG1012	belongs to the aldehyde dehydrogenase family
AWJ20_2660	COG1902	pentaerythritol trinitrate reductase activity
AWJ20_2661	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_2665	COG2814	Major facilitator Superfamily
AWJ20_2667	COG0085	RNA polymerase activity
AWJ20_267	COG1012	belongs to the aldehyde dehydrogenase family
AWJ20_268	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AWJ20_2685	COG0596	Alpha beta hydrolase
AWJ20_2686	COG1222	aaa ATPase
AWJ20_2698	COG1063	alcohol dehydrogenase
AWJ20_2700	COG2815	serine threonine protein kinase
AWJ20_2700	COG0515	serine threonine protein kinase
AWJ20_2704	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AWJ20_271	COG0513	Belongs to the DEAD box helicase family
AWJ20_2711	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AWJ20_2712	COG0531	amino acid
AWJ20_2714	COG0655	NAD(P)H dehydrogenase (quinone) activity
AWJ20_2718	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWJ20_273	COG0656	L-ascorbic acid biosynthetic process
AWJ20_2732	COG1793	dna ligase
AWJ20_2733	COG0515	serine threonine protein kinase
AWJ20_2733	COG2815	serine threonine protein kinase
AWJ20_2735	COG0318	PFAM AMP-dependent synthetase and ligase
AWJ20_2736	COG0473	3-isopropylmalate dehydrogenase activity
AWJ20_2740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWJ20_2740	COG2124	cytochrome p450
AWJ20_2741	COG1185	polyribonucleotide nucleotidyltransferase activity
AWJ20_2743	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWJ20_2758	COG1063	alcohol dehydrogenase
AWJ20_2761	COG2124	cytochrome p450
AWJ20_2762	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_2763	COG2814	Major facilitator Superfamily
AWJ20_2764	COG0179	Fumarylacetoacetate (FAA) hydrolase
AWJ20_2773	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AWJ20_2779	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWJ20_278	COG0477	Major facilitator Superfamily
AWJ20_2785	COG2046	Belongs to the sulfate adenylyltransferase family
AWJ20_2785	COG0529	Catalyzes the synthesis of activated sulfate
AWJ20_2789	COG0517	IMP dehydrogenase activity
AWJ20_2789	COG0516	GMP reductase activity
AWJ20_2790	COG3118	belongs to the thioredoxin family
AWJ20_2795	COG1132	(ABC) transporter
AWJ20_2797	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AWJ20_2799	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AWJ20_2800	COG1819	glycosyl
AWJ20_2805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AWJ20_281	COG0823	Involved in the tonB-independent uptake of proteins
AWJ20_282	COG0175	sulfate reduction
AWJ20_2833	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWJ20_2838	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWJ20_2842	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWJ20_2842	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AWJ20_2847	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWJ20_285	COG0450	alkyl hydroperoxide reductase
AWJ20_2858	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AWJ20_2859	COG0114	fumarate hydratase activity
AWJ20_2867	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AWJ20_2886	COG0076	glutamate decarboxylase activity
AWJ20_289	COG0542	response to heat
AWJ20_2893	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AWJ20_2894	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AWJ20_2898	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWJ20_2900	COG2815	serine threonine protein kinase
AWJ20_2900	COG0515	serine threonine protein kinase
AWJ20_2901	COG0039	L-malate dehydrogenase activity
AWJ20_2905	COG2217	Heavy metal translocating P-type atpase
AWJ20_2907	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AWJ20_2907	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AWJ20_2919	COG3104	oligopeptide transport
AWJ20_2922	COG0588	phosphoglycerate mutase activity
AWJ20_2927	COG0724	RNA recognition motif
AWJ20_2929	COG1914	H( )-stimulated, divalent metal cation uptake system
AWJ20_2932	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWJ20_2933	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AWJ20_2939	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AWJ20_2941	COG2175	clavaminate synthase activity
AWJ20_2945	COG2072	flavoprotein involved in K transport
AWJ20_2950	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AWJ20_2952	COG0423	glycine-tRNA ligase activity
AWJ20_2978	COG0203	ribosomal protein L17
AWJ20_2983	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AWJ20_3004	COG1131	(ABC) transporter
AWJ20_301	COG2814	Major facilitator Superfamily
AWJ20_3014	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWJ20_302	COG0673	inositol 2-dehydrogenase activity
AWJ20_3020	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AWJ20_3024	COG2815	serine threonine protein kinase
AWJ20_3024	COG0515	serine threonine protein kinase
AWJ20_3025	COG0563	adenylate kinase activity
AWJ20_3031	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AWJ20_3035	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AWJ20_304	COG4948	Mandelate Racemase Muconate Lactonizing
AWJ20_3041	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AWJ20_3057	COG0138	bifunctional purine biosynthesis protein purh
AWJ20_3064	COG2873	o-acetylhomoserine
AWJ20_307	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AWJ20_3073	COG2175	clavaminate synthase activity
AWJ20_3078	COG1185	polyribonucleotide nucleotidyltransferase activity
AWJ20_3082	COG1205	dead DEAH box helicase
AWJ20_3082	COG1111	helicase
AWJ20_3087	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWJ20_3093	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AWJ20_3094	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWJ20_3095	COG0515	serine threonine protein kinase
AWJ20_3099	COG2706	6-phosphogluconolactonase activity
AWJ20_310	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AWJ20_3108	COG0217	transcriptional regulatory protein
AWJ20_3123	COG1233	COG1233 Phytoene dehydrogenase and related
AWJ20_3124	COG0004	ammonium transporteR
AWJ20_3125	COG0484	heat shock protein binding
AWJ20_3126	COG0456	acetyltransferase
AWJ20_3128	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWJ20_3134	COG0513	Belongs to the DEAD box helicase family
AWJ20_3138	COG2815	serine threonine protein kinase
AWJ20_3138	COG0515	serine threonine protein kinase
AWJ20_3140	COG0656	L-ascorbic acid biosynthetic process
AWJ20_3141	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWJ20_3141	COG3153	acetyltransferase
AWJ20_3145	COG1252	NADH dehydrogenase
AWJ20_3146	COG0543	2 iron, 2 sulfur cluster binding
AWJ20_3146	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWJ20_3147	COG0527	aspartate kinase activity
AWJ20_3150	COG0475	glutathione-regulated potassium exporter activity
AWJ20_3156	COG0560	Phosphoserine phosphatase
AWJ20_3156	COG3830	Belongs to the UPF0237 family
AWJ20_3161	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWJ20_3162	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AWJ20_3165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AWJ20_3168	COG0571	ribonuclease III activity
AWJ20_3187	COG1346	cytolysis
AWJ20_3189	COG0515	serine threonine protein kinase
AWJ20_3189	COG2815	serine threonine protein kinase
AWJ20_3200	COG1953	Uracil, thiamine, allantoin
AWJ20_3203	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWJ20_3203	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AWJ20_3212	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWJ20_3212	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWJ20_3228	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWJ20_3229	COG0484	heat shock protein binding
AWJ20_3230	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AWJ20_325	COG0442	prolyl-tRNA aminoacylation
AWJ20_3251	COG0006	proline dipeptidase activity
AWJ20_3253	COG4948	Mandelate Racemase Muconate Lactonizing
AWJ20_3259	COG2814	Major facilitator Superfamily
AWJ20_3260	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_3261	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWJ20_3261	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWJ20_3264	COG1774	PSP1 C-terminal conserved region
AWJ20_3265	COG0271	Belongs to the BolA IbaG family
AWJ20_3272	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWJ20_3279	COG4178	(ABC) transporter
AWJ20_328	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AWJ20_3281	COG0515	serine threonine protein kinase
AWJ20_3291	COG2084	Dehydrogenase
AWJ20_3295	COG4948	Mandelate Racemase Muconate Lactonizing
AWJ20_3311	COG1024	Enoyl-CoA hydratase
AWJ20_3312	COG0049	tRNA binding
AWJ20_3315	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AWJ20_3325	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AWJ20_3326	COG1643	Atp-dependent helicase
AWJ20_3329	COG2895	sulfate adenylyltransferase (ATP) activity
AWJ20_3333	COG2814	Major facilitator Superfamily
AWJ20_3335	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AWJ20_3338	COG1132	(ABC) transporter
AWJ20_334	COG0459	protein refolding
AWJ20_3345	COG0515	serine threonine protein kinase
AWJ20_3345	COG2815	serine threonine protein kinase
AWJ20_3350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AWJ20_3350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWJ20_3351	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_3362	COG0515	serine threonine protein kinase
AWJ20_3362	COG2815	serine threonine protein kinase
AWJ20_3367	COG4948	Mandelate Racemase Muconate Lactonizing
AWJ20_3368	COG4948	Mandelate Racemase Muconate Lactonizing
AWJ20_3369	COG1304	FMN binding
AWJ20_3372	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_3374	COG0633	Ferredoxin
AWJ20_3374	COG3217	Mosc domain protein beta barrel domain protein
AWJ20_339	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AWJ20_3390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AWJ20_340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AWJ20_3401	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AWJ20_3411	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWJ20_3415	COG0167	dihydroorotate dehydrogenase activity
AWJ20_3417	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_3418	COG0393	Putative heavy-metal-binding
AWJ20_3419	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AWJ20_3421	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AWJ20_3432	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AWJ20_3438	COG3579	cysteine-type endopeptidase activity
AWJ20_3439	COG0656	L-ascorbic acid biosynthetic process
AWJ20_3460	COG2234	aminopeptidase activity
AWJ20_3462	COG1648	precorrin-2 dehydrogenase activity
AWJ20_3462	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWJ20_3466	COG0484	heat shock protein binding
AWJ20_3470	COG0626	cystathionine gamma-synthase activity
AWJ20_348	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWJ20_3480	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AWJ20_3482	COG1331	Highly conserved protein containing a thioredoxin domain
AWJ20_3484	COG0129	dihydroxy-acid dehydratase activity
AWJ20_3493	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AWJ20_3494	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWJ20_3495	COG0137	argininosuccinate synthase activity
AWJ20_3500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWJ20_3500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWJ20_3505	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AWJ20_3508	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWJ20_3511	COG0656	L-ascorbic acid biosynthetic process
AWJ20_3520	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AWJ20_3524	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AWJ20_3525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AWJ20_353	COG0833	amino acid
AWJ20_3531	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AWJ20_3532	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AWJ20_3535	COG2897	thiosulfate sulfurtransferase activity
AWJ20_3538	COG2351	hydroxyisourate hydrolase activity
AWJ20_3544	COG1716	ATPase activity
AWJ20_3544	COG0842	Transport permease protein
AWJ20_3544	COG1131	(ABC) transporter
AWJ20_3548	COG2814	Major facilitator Superfamily
AWJ20_3549	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWJ20_355	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWJ20_3553	COG2814	Major facilitator Superfamily
AWJ20_3559	COG1643	Atp-dependent helicase
AWJ20_356	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AWJ20_3562	COG1584	GPR1 FUN34 yaaH family protein
AWJ20_3564	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AWJ20_3567	COG0655	NAD(P)H dehydrogenase (quinone) activity
AWJ20_3568	COG0655	NAD(P)H dehydrogenase (quinone) activity
AWJ20_3570	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AWJ20_3574	COG0085	RNA polymerase activity
AWJ20_3584	COG0515	serine threonine protein kinase
AWJ20_3584	COG2815	serine threonine protein kinase
AWJ20_359	COG1012	belongs to the aldehyde dehydrogenase family
AWJ20_3595	COG2814	Major facilitator Superfamily
AWJ20_36	COG0277	FAD linked oxidase domain protein
AWJ20_360	COG1064	alcohol dehydrogenase
AWJ20_3601	COG0191	fructose-bisphosphate aldolase activity
AWJ20_3608	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AWJ20_3610	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AWJ20_3632	COG0523	cobalamin synthesis protein
AWJ20_3640	COG0515	serine threonine protein kinase
AWJ20_3641	COG1132	(ABC) transporter
AWJ20_3645	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWJ20_3651	COG1113	amino acid transport
AWJ20_3652	COG1113	amino acid transport
AWJ20_367	COG0076	glutamate decarboxylase activity
AWJ20_3670	COG0512	Glutamine amidotransferase of anthranilate synthase
AWJ20_3672	COG0463	Glycosyl transferase, family 2
AWJ20_3675	COG0402	S-adenosylhomocysteine deaminase activity
AWJ20_3676	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AWJ20_3677	COG0489	protein tyrosine kinase activity
AWJ20_3688	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWJ20_3689	COG1643	Atp-dependent helicase
AWJ20_3691	COG2175	clavaminate synthase activity
AWJ20_371	COG2226	methyltransferase
AWJ20_3711	COG0484	heat shock protein binding
AWJ20_3719	COG2815	serine threonine protein kinase
AWJ20_3719	COG0515	serine threonine protein kinase
AWJ20_3720	COG0038	chloride channel
AWJ20_3728	COG0515	serine threonine protein kinase
AWJ20_3730	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AWJ20_3732	COG0513	Belongs to the DEAD box helicase family
AWJ20_3737	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AWJ20_374	COG2223	nitrite transmembrane transporter activity
AWJ20_3747	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AWJ20_3748	COG0017	Asparaginyl-tRNA synthetase
AWJ20_3749	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_376	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AWJ20_3760	COG0439	Biotin carboxylase
AWJ20_3763	COG0308	aminopeptidase N
AWJ20_3765	COG0515	serine threonine protein kinase
AWJ20_3765	COG2815	serine threonine protein kinase
AWJ20_3766	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWJ20_3774	COG0051	transcription antitermination factor activity, RNA binding
AWJ20_3783	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_3784	COG1490	D-aminoacyl-tRNA deacylase activity
AWJ20_3786	COG1131	(ABC) transporter
AWJ20_3786	COG1716	ATPase activity
AWJ20_3786	COG0842	Transport permease protein
AWJ20_3787	COG0842	Transport permease protein
AWJ20_3787	COG1131	(ABC) transporter
AWJ20_3787	COG1716	ATPase activity
AWJ20_3796	COG2814	Major facilitator Superfamily
AWJ20_3800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AWJ20_3811	COG0726	polysaccharide deacetylase
AWJ20_3814	COG2217	Heavy metal translocating P-type atpase
AWJ20_3815	COG0588	phosphoglycerate mutase activity
AWJ20_3826	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AWJ20_3827	COG1960	acyl-CoA dehydrogenase activity
AWJ20_3829	COG0004	ammonium transporteR
AWJ20_383	COG0179	Fumarylacetoacetate (FAA) hydrolase
AWJ20_3831	COG0495	leucyl-tRNA aminoacylation
AWJ20_3834	COG1196	nuclear chromosome segregation
AWJ20_384	COG2131	deaminase
AWJ20_3842	COG0656	L-ascorbic acid biosynthetic process
AWJ20_3847	COG0670	Belongs to the BI1 family
AWJ20_3852	COG0513	Belongs to the DEAD box helicase family
AWJ20_3854	COG1404	Belongs to the peptidase S8 family
AWJ20_3858	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWJ20_3858	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AWJ20_3859	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AWJ20_386	COG0688	phosphatidylethanolamine metabolic process
AWJ20_3860	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AWJ20_3864	COG0515	serine threonine protein kinase
AWJ20_3864	COG2815	serine threonine protein kinase
AWJ20_3880	COG0531	amino acid
AWJ20_3882	COG5277	cytoskeleton organization
AWJ20_3884	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWJ20_3889	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AWJ20_3894	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AWJ20_3899	COG1362	aminopeptidase activity
AWJ20_390	COG1231	oxidoreductase activity
AWJ20_3903	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWJ20_3904	COG0318	PFAM AMP-dependent synthetase and ligase
AWJ20_3918	COG1785	Belongs to the alkaline phosphatase family
AWJ20_3919	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWJ20_3922	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AWJ20_3930	COG2070	2-Nitropropane dioxygenase
AWJ20_3931	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AWJ20_3934	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AWJ20_394	COG0142	geranyltranstransferase activity
AWJ20_3947	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWJ20_395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AWJ20_3952	COG0076	glutamate decarboxylase activity
AWJ20_3954	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AWJ20_397	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AWJ20_3973	COG0018	arginyl-trna synthetase
AWJ20_3975	COG0521	Mo-molybdopterin cofactor biosynthetic process
AWJ20_3976	COG0833	amino acid
AWJ20_3988	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AWJ20_3997	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWJ20_4	COG0724	RNA recognition motif
AWJ20_4006	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AWJ20_4009	COG0656	L-ascorbic acid biosynthetic process
AWJ20_4014	COG4122	O-methyltransferase activity
AWJ20_4018	COG0539	negative regulation of cytoplasmic translation
AWJ20_4020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AWJ20_4022	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AWJ20_4023	COG1472	Belongs to the glycosyl hydrolase 3 family
AWJ20_4029	COG2814	Major facilitator Superfamily
AWJ20_4031	COG2815	serine threonine protein kinase
AWJ20_4031	COG0515	serine threonine protein kinase
AWJ20_4040	COG3961	Belongs to the TPP enzyme family
AWJ20_4047	COG0165	Argininosuccinate lyase
AWJ20_4049	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AWJ20_4050	COG0515	serine threonine protein kinase
AWJ20_4050	COG2815	serine threonine protein kinase
AWJ20_4053	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AWJ20_4060	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AWJ20_4065	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AWJ20_4066	COG0012	GTP binding
AWJ20_4073	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AWJ20_4074	COG0724	RNA recognition motif
AWJ20_4077	COG1070	Carbohydrate kinase
AWJ20_4087	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AWJ20_4089	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWJ20_4091	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AWJ20_4092	COG0459	protein refolding
AWJ20_4107	COG2175	clavaminate synthase activity
AWJ20_411	COG0039	L-malate dehydrogenase activity
AWJ20_4112	COG0037	tRNA processing
AWJ20_4118	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AWJ20_4121	COG2890	protein-(glutamine-N5) methyltransferase activity
AWJ20_4138	COG0514	ATP-dependent DNA helicase (RecQ)
AWJ20_4143	COG0440	acetolactate synthase activity
AWJ20_4148	COG0443	Heat shock 70 kDa protein
AWJ20_4149	COG0625	glutathione transferase activity
AWJ20_4151	COG0571	ribonuclease III activity
AWJ20_4163	COG1132	(ABC) transporter
AWJ20_4165	COG0517	IMP dehydrogenase activity
AWJ20_4165	COG0516	GMP reductase activity
AWJ20_4169	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AWJ20_4173	COG4702	Belongs to the UPF0303 family
AWJ20_418	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AWJ20_4187	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AWJ20_419	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_4192	COG2723	6-phospho-beta-galactosidase activity
AWJ20_4194	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWJ20_4196	COG0702	epimerase
AWJ20_4213	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWJ20_4223	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
AWJ20_423	COG2119	membrane
AWJ20_4235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWJ20_4239	COG3437	response regulator, receiver
AWJ20_4239	COG3850	Histidine kinase
AWJ20_4239	COG4999	Histidine kinase
AWJ20_4239	COG2205	protein histidine kinase activity
AWJ20_4242	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AWJ20_4246	COG1335	isochorismatase
AWJ20_4247	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AWJ20_4258	COG0459	protein refolding
AWJ20_4266	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AWJ20_427	COG0417	DNA replication proofreading
AWJ20_4272	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AWJ20_4275	COG0833	amino acid
AWJ20_428	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AWJ20_4286	COG1234	tRNA 3'-trailer cleavage
AWJ20_4294	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_43	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AWJ20_4308	COG5265	(ABC) transporter
AWJ20_432	COG0552	protein localization to endoplasmic reticulum
AWJ20_4321	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_4322	COG4999	Histidine kinase
AWJ20_4322	COG3437	response regulator, receiver
AWJ20_4322	COG2205	protein histidine kinase activity
AWJ20_4322	COG3850	Histidine kinase
AWJ20_4324	COG0154	amidase activity
AWJ20_4333	COG0564	pseudouridine synthase activity
AWJ20_4336	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AWJ20_4349	COG0484	heat shock protein binding
AWJ20_4352	COG1648	precorrin-2 dehydrogenase activity
AWJ20_4352	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AWJ20_4354	COG1012	belongs to the aldehyde dehydrogenase family
AWJ20_4355	COG0233	cytoplasmic translational termination
AWJ20_4365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AWJ20_4366	COG1442	glycosyl transferase family 8
AWJ20_4375	COG0649	NAD binding
AWJ20_4379	COG0563	adenylate kinase activity
AWJ20_4400	COG0405	Gamma-glutamyltransferase
AWJ20_4402	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AWJ20_4428	COG0285	dihydrofolate synthase activity
AWJ20_4431	COG2814	Major facilitator Superfamily
AWJ20_4432	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AWJ20_4442	COG0484	heat shock protein binding
AWJ20_4446	COG0277	FAD linked oxidase domain protein
AWJ20_4448	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWJ20_4463	COG0237	dephospho-CoA kinase activity
AWJ20_4464	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AWJ20_4472	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_4474	COG0515	serine threonine protein kinase
AWJ20_4474	COG2815	serine threonine protein kinase
AWJ20_4479	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AWJ20_4481	COG0287	Prephenate dehydrogenase
AWJ20_4496	COG0187	DNA topoisomerase II activity
AWJ20_4510	COG1448	Aminotransferase
AWJ20_4514	COG0515	serine threonine protein kinase
AWJ20_4526	COG0235	Class ii aldolase
AWJ20_4531	COG1183	phosphatidylcholine synthase activity
AWJ20_4536	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AWJ20_4538	COG0367	asparagine synthase
AWJ20_4541	COG0326	Molecular chaperone. Has ATPase activity
AWJ20_4549	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AWJ20_4549	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AWJ20_4562	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AWJ20_4568	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AWJ20_4574	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWJ20_4578	COG0052	Belongs to the universal ribosomal protein uS2 family
AWJ20_4582	COG2937	Belongs to the GPAT DAPAT family
AWJ20_4586	COG2807	transmembrane transport
AWJ20_4589	COG0488	(ABC) transporter
AWJ20_4590	COG1058	Belongs to the CinA family
AWJ20_4590	COG1546	Belongs to the CinA family
AWJ20_46	COG2814	Major facilitator Superfamily
AWJ20_460	COG0563	adenylate kinase activity
AWJ20_4602	COG1012	belongs to the aldehyde dehydrogenase family
AWJ20_4608	COG0626	cystathionine gamma-synthase activity
AWJ20_4616	COG0024	Methionine aminopeptidase
AWJ20_4617	COG2814	Major facilitator Superfamily
AWJ20_4628	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AWJ20_463	COG0513	Belongs to the DEAD box helicase family
AWJ20_4637	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AWJ20_4638	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWJ20_4645	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWJ20_4645	COG0047	phosphoribosylformylglycinamidine synthase activity
AWJ20_4652	COG2272	Belongs to the type-B carboxylesterase lipase family
AWJ20_4654	COG0194	GDP metabolic process
AWJ20_4663	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AWJ20_4665	COG0450	alkyl hydroperoxide reductase
AWJ20_467	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AWJ20_4673	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AWJ20_4685	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AWJ20_4689	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AWJ20_4699	COG1053	succinate dehydrogenase
AWJ20_4701	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWJ20_4718	COG2814	Major facilitator Superfamily
AWJ20_472	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AWJ20_472	COG2124	cytochrome p450
AWJ20_4720	COG0515	serine threonine protein kinase
AWJ20_4720	COG2815	serine threonine protein kinase
AWJ20_4727	COG2890	protein-(glutamine-N5) methyltransferase activity
AWJ20_4741	COG0745	RESPONSE REGULATOR receiver
AWJ20_4742	COG2815	serine threonine protein kinase
AWJ20_4742	COG0515	serine threonine protein kinase
AWJ20_4747	COG2130	NADP-dependent
AWJ20_4751	COG0154	amidase activity
AWJ20_4752	COG3265	gluconokinase activity
AWJ20_4758	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWJ20_4776	COG0724	RNA recognition motif
AWJ20_4783	COG1136	(ABC) transporter
AWJ20_4789	COG0443	Heat shock 70 kDa protein
AWJ20_4790	COG4178	(ABC) transporter
AWJ20_4796	COG0302	gtp cyclohydrolase
AWJ20_4802	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AWJ20_4805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWJ20_4805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWJ20_4824	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AWJ20_4826	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AWJ20_4831	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AWJ20_4835	COG0003	Pfam Anion-transporting ATPase
AWJ20_4842	COG0081	regulation of translation
AWJ20_4843	COG2226	methyltransferase
AWJ20_4844	COG0033	Phosphoglucomutase
AWJ20_4852	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AWJ20_4863	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AWJ20_4879	COG2224	Isocitrate lyase
AWJ20_49	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AWJ20_4903	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AWJ20_4926	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AWJ20_4937	COG0477	Major facilitator Superfamily
AWJ20_4940	COG2814	Major facilitator Superfamily
AWJ20_4943	COG0515	serine threonine protein kinase
AWJ20_4944	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_4946	COG1063	alcohol dehydrogenase
AWJ20_4947	COG0833	amino acid
AWJ20_495	COG2814	Major facilitator Superfamily
AWJ20_4952	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_4954	COG0488	(ABC) transporter
AWJ20_4955	COG0557	exoribonuclease II activity
AWJ20_4958	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_496	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_4969	COG1162	GTPase activity
AWJ20_497	COG1132	(ABC) transporter
AWJ20_4970	COG0515	serine threonine protein kinase
AWJ20_4971	COG0567	Dehydrogenase, E1 component
AWJ20_4980	COG0833	amino acid
AWJ20_4981	COG0833	amino acid
AWJ20_4990	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AWJ20_4994	COG0183	Belongs to the thiolase family
AWJ20_50	COG2175	clavaminate synthase activity
AWJ20_500	COG0833	amino acid
AWJ20_5002	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AWJ20_5009	COG0123	including yeast histone deacetylase and acetoin utilization protein
AWJ20_501	COG0833	amino acid
AWJ20_5021	COG0408	coproporphyrinogen oxidase activity
AWJ20_5024	COG1612	heme a metabolic process
AWJ20_5031	COG0515	serine threonine protein kinase
AWJ20_5031	COG2815	serine threonine protein kinase
AWJ20_5034	COG0822	iron-sulfur transferase activity
AWJ20_5039	COG3844	kynureninase activity
AWJ20_5040	COG0067	glutamate synthase
AWJ20_5040	COG0069	glutamate synthase activity
AWJ20_5040	COG0070	glutamate synthase
AWJ20_505	COG3285	dna ligase
AWJ20_505	COG1793	dna ligase
AWJ20_5050	COG2814	Major facilitator Superfamily
AWJ20_5057	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AWJ20_5058	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AWJ20_5059	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AWJ20_5067	COG0288	reversible hydration of carbon dioxide
AWJ20_5069	COG3118	belongs to the thioredoxin family
AWJ20_5078	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWJ20_5085	COG0101	tRNA pseudouridine synthase activity
AWJ20_5086	COG0513	Belongs to the DEAD box helicase family
AWJ20_5096	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AWJ20_510	COG0626	cystathionine gamma-synthase activity
AWJ20_5103	COG0557	exoribonuclease II activity
AWJ20_5107	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AWJ20_5109	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AWJ20_5125	COG1017	nitric oxide dioxygenase activity
AWJ20_5125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AWJ20_5128	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWJ20_5129	COG0473	3-isopropylmalate dehydrogenase activity
AWJ20_513	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AWJ20_5131	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWJ20_5134	COG0525	valine-tRNA ligase activity
AWJ20_5136	COG1643	Atp-dependent helicase
AWJ20_5139	COG1914	H( )-stimulated, divalent metal cation uptake system
AWJ20_5146	COG2815	serine threonine protein kinase
AWJ20_5146	COG0515	serine threonine protein kinase
AWJ20_5148	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AWJ20_515	COG0514	ATP-dependent DNA helicase (RecQ)
AWJ20_5159	COG1104	cysteine desulfurase activity
AWJ20_5160	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AWJ20_5161	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWJ20_5162	COG2815	serine threonine protein kinase
AWJ20_5162	COG0515	serine threonine protein kinase
AWJ20_5178	COG0432	Pfam Uncharacterised protein family UPF0047
AWJ20_518	COG0028	Belongs to the TPP enzyme family
AWJ20_5190	COG1394	ATPase activity, coupled to movement of substances
AWJ20_5192	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWJ20_5198	COG2271	Major facilitator Superfamily
AWJ20_5200	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AWJ20_5203	COG1250	3-hydroxyacyl-CoA dehydrogenase
AWJ20_5215	COG0656	L-ascorbic acid biosynthetic process
AWJ20_5227	COG0417	DNA replication proofreading
AWJ20_5235	COG0542	response to heat
AWJ20_5240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AWJ20_5242	COG0363	glucosamine-6-phosphate deaminase activity
AWJ20_5243	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AWJ20_5244	COG2072	flavoprotein involved in K transport
AWJ20_5247	COG0688	phosphatidylethanolamine metabolic process
AWJ20_5248	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWJ20_5269	COG0515	serine threonine protein kinase
AWJ20_5274	COG0596	Alpha beta hydrolase
AWJ20_5278	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AWJ20_5280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWJ20_5283	COG4221	oxidoreductase activity
AWJ20_529	COG0667	Aldo Keto reductase
AWJ20_53	COG0484	heat shock protein binding
AWJ20_5304	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AWJ20_5322	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWJ20_5323	COG1448	Aminotransferase
AWJ20_5329	COG0277	FAD linked oxidase domain protein
AWJ20_5344	COG0477	Major facilitator Superfamily
AWJ20_5344	COG2814	Major facilitator Superfamily
AWJ20_5346	COG2814	Major facilitator Superfamily
AWJ20_539	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AWJ20_541	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AWJ20_551	COG1362	aminopeptidase activity
AWJ20_555	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AWJ20_557	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AWJ20_559	COG0200	Binds to the 23S rRNA
AWJ20_560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AWJ20_567	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AWJ20_568	COG5520	Belongs to the glycosyl hydrolase 30 family
AWJ20_575	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_576	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_588	COG0667	Aldo Keto reductase
AWJ20_589	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_59	COG0017	Asparaginyl-tRNA synthetase
AWJ20_597	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AWJ20_606	COG2814	Major facilitator Superfamily
AWJ20_609	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AWJ20_618	COG1444	tRNA N-acetyltransferase activity
AWJ20_626	COG0534	Mate efflux family protein
AWJ20_630	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_633	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWJ20_634	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AWJ20_636	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AWJ20_649	COG0484	heat shock protein binding
AWJ20_652	COG2814	Major facilitator Superfamily
AWJ20_655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AWJ20_657	COG0281	malic enzyme
AWJ20_658	COG0281	malic enzyme
AWJ20_659	COG0281	malic enzyme
AWJ20_662	COG2132	Multicopper oxidase
AWJ20_675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AWJ20_676	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AWJ20_68	COG2816	NAD+ diphosphatase activity
AWJ20_681	COG0045	succinate-CoA ligase (ADP-forming) activity
AWJ20_687	COG2814	Major facilitator Superfamily
AWJ20_688	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AWJ20_692	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWJ20_70	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AWJ20_715	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AWJ20_718	COG0443	Heat shock 70 kDa protein
AWJ20_72	COG0484	heat shock protein binding
AWJ20_724	COG0352	thiamine-phosphate diphosphorylase activity
AWJ20_729	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AWJ20_735	COG0181	hydroxymethylbilane synthase activity
AWJ20_740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWJ20_748	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AWJ20_760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWJ20_765	COG1028	Short-chain dehydrogenase reductase Sdr
AWJ20_766	COG2224	Isocitrate lyase
AWJ20_772	COG1643	Atp-dependent helicase
AWJ20_775	COG2271	Major facilitator Superfamily
AWJ20_776	COG0585	pseudouridine synthase activity
AWJ20_780	COG1643	Atp-dependent helicase
AWJ20_781	COG0149	triose-phosphate isomerase activity
AWJ20_788	COG2814	Major facilitator Superfamily
AWJ20_79	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AWJ20_790	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AWJ20_797	COG0484	heat shock protein binding
AWJ20_803	COG0482	sulfurtransferase activity
AWJ20_806	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWJ20_816	COG1025	Belongs to the peptidase M16 family
AWJ20_820	COG2814	Major facilitator Superfamily
AWJ20_823	COG0515	serine threonine protein kinase
AWJ20_828	COG0157	Belongs to the NadC ModD family
AWJ20_833	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AWJ20_838	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWJ20_854	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AWJ20_857	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AWJ20_859	COG2815	serine threonine protein kinase
AWJ20_859	COG0515	serine threonine protein kinase
AWJ20_86	COG0343	queuine tRNA-ribosyltransferase activity
AWJ20_861	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AWJ20_865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWJ20_870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AWJ20_898	COG0443	Heat shock 70 kDa protein
AWJ20_90	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AWJ20_906	COG2271	Major facilitator Superfamily
AWJ20_914	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AWJ20_922	COG1472	Belongs to the glycosyl hydrolase 3 family
AWJ20_926	COG0656	L-ascorbic acid biosynthetic process
AWJ20_928	COG2814	Major facilitator Superfamily
AWJ20_933	COG0330	HflC and HflK could
AWJ20_934	COG2226	methyltransferase
AWJ20_943	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AWJ20_945	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AWJ20_957	COG1088	dTDP-glucose 4,6-dehydratase activity
AWJ20_958	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AWJ20_96	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWJ20_963	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AWJ20_965	COG0484	heat shock protein binding
AWJ20_974	COG0626	cystathionine gamma-synthase activity
AWJ20_976	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AWJ20_978	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AWJ20_981	COG0513	Belongs to the DEAD box helicase family
AWJ20_984	COG0101	tRNA pseudouridine synthase activity
AWJ20_988	COG0222	ribosome binding
AWJ20_999	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient