locus-tag	class	description
J3U87_RS00010	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS00020	COG0515	serine threonine protein kinase
J3U87_RS00020	COG2815	serine threonine protein kinase
J3U87_RS00030	COG0557	exoribonuclease II activity
J3U87_RS00040	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J3U87_RS00045	COG3275	phosphorelay sensor kinase activity
J3U87_RS00070	COG3852	Histidine kinase
J3U87_RS00095	COG0312	modulator of DNA gyrase
J3U87_RS00100	COG0312	modulator of DNA gyrase
J3U87_RS00105	COG0739	heme binding
J3U87_RS00115	COG4771	TonB-dependent receptor
J3U87_RS00140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J3U87_RS00145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS00175	COG1957	nucleoside hydrolase
J3U87_RS00200	COG0583	DNA-binding transcription factor activity
J3U87_RS00215	COG0542	response to heat
J3U87_RS00220	COG0542	response to heat
J3U87_RS00225	COG0542	response to heat
J3U87_RS00230	COG0300	oxidoreductase activity
J3U87_RS00245	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J3U87_RS00245	COG1918	ferrous iron import across plasma membrane
J3U87_RS00250	COG1918	ferrous iron import across plasma membrane
J3U87_RS00290	COG0372	Belongs to the citrate synthase family
J3U87_RS00295	COG0372	Belongs to the citrate synthase family
J3U87_RS00300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J3U87_RS00320	COG0612	Peptidase, M16
J3U87_RS00325	COG0612	Peptidase, M16
J3U87_RS00330	COG0326	Molecular chaperone. Has ATPase activity
J3U87_RS00335	COG3279	Response regulator of the LytR AlgR family
J3U87_RS00435	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J3U87_RS00435	COG0515	serine threonine protein kinase
J3U87_RS00460	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J3U87_RS00575	COG1164	Oligoendopeptidase f
J3U87_RS00590	COG2204	response regulator
J3U87_RS00600	COG0577	efflux transmembrane transporter activity
J3U87_RS00600	COG1136	(ABC) transporter
J3U87_RS00650	COG1518	maintenance of DNA repeat elements
J3U87_RS00680	COG0024	Methionine aminopeptidase
J3U87_RS00770	COG2204	response regulator
J3U87_RS00775	COG0784	Response regulator, receiver
J3U87_RS00775	COG2205	protein histidine kinase activity
J3U87_RS00790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J3U87_RS00840	COG0463	Glycosyl transferase, family 2
J3U87_RS00850	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J3U87_RS00885	COG1127	ABC transporter
J3U87_RS00890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J3U87_RS00900	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
J3U87_RS00905	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
J3U87_RS00915	COG0714	Associated with various cellular activities
J3U87_RS00945	COG0784	Response regulator, receiver
J3U87_RS00945	COG0835	chemotaxis
J3U87_RS00970	COG4771	TonB-dependent receptor
J3U87_RS00995	COG2304	oxidoreductase activity
J3U87_RS01015	COG0714	Associated with various cellular activities
J3U87_RS01040	COG0438	transferase activity, transferring glycosyl groups
J3U87_RS01040	COG0297	glycogen (starch) synthase activity
J3U87_RS01065	COG0515	serine threonine protein kinase
J3U87_RS01065	COG2815	serine threonine protein kinase
J3U87_RS01110	COG1271	oxidase subunit
J3U87_RS01115	COG2815	serine threonine protein kinase
J3U87_RS01115	COG0515	serine threonine protein kinase
J3U87_RS01120	COG0612	Peptidase, M16
J3U87_RS01125	COG0826	peptidase U32
J3U87_RS01140	COG1132	(ABC) transporter
J3U87_RS01145	COG1132	(ABC) transporter
J3U87_RS01150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J3U87_RS01150	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
J3U87_RS01175	COG5001	Diguanylate cyclase
J3U87_RS01185	COG0745	RESPONSE REGULATOR receiver
J3U87_RS01190	COG2205	protein histidine kinase activity
J3U87_RS01200	COG0301	tRNA thio-modification
J3U87_RS01200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J3U87_RS01230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J3U87_RS01235	COG1960	acyl-CoA dehydrogenase activity
J3U87_RS01240	COG0183	Belongs to the thiolase family
J3U87_RS01245	COG1250	3-hydroxyacyl-CoA dehydrogenase
J3U87_RS01245	COG1024	Enoyl-CoA hydratase
J3U87_RS01250	COG1309	transcriptional regulator
J3U87_RS01260	COG2130	NADP-dependent
J3U87_RS01285	COG2255	four-way junction helicase activity
J3U87_RS01300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J3U87_RS01330	COG2224	Isocitrate lyase
J3U87_RS01335	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J3U87_RS01355	COG0804	urea catabolic process
J3U87_RS01375	COG1404	Belongs to the peptidase S8 family
J3U87_RS01390	COG0678	peroxiredoxin activity
J3U87_RS01390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J3U87_RS01415	COG2885	chlorophyll binding
J3U87_RS01415	COG3047	cAMP biosynthetic process
J3U87_RS01435	COG0643	Histidine kinase
J3U87_RS01435	COG0784	Response regulator, receiver
J3U87_RS01435	COG2198	Histidine kinase
J3U87_RS01450	COG0840	transmembrane signaling receptor activity
J3U87_RS01475	COG1366	Belongs to the anti-sigma-factor antagonist family
J3U87_RS01495	COG4792	protein secretion
J3U87_RS01500	COG4791	protein targeting
J3U87_RS01505	COG4794	Type iii secretion
J3U87_RS01510	COG4790	Type iii secretion
J3U87_RS01635	COG0589	response to stress
J3U87_RS01640	COG4191	Histidine kinase
J3U87_RS01640	COG0784	Response regulator, receiver
J3U87_RS01660	COG1132	(ABC) transporter
J3U87_RS01670	COG0535	radical SAM domain protein
J3U87_RS01690	COG0784	Response regulator, receiver
J3U87_RS01690	COG4191	Histidine kinase
J3U87_RS01705	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS01720	COG3291	Pkd domain containing protein
J3U87_RS01725	COG3710	Transcriptional regulator
J3U87_RS01730	COG1368	sulfuric ester hydrolase activity
J3U87_RS01745	COG3447	MASE1 domain protein
J3U87_RS01745	COG5001	Diguanylate cyclase
J3U87_RS01745	COG5002	protein histidine kinase activity
J3U87_RS01765	COG0488	(ABC) transporter
J3U87_RS01780	COG1404	Belongs to the peptidase S8 family
J3U87_RS01800	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
J3U87_RS01805	COG0235	Class ii aldolase
J3U87_RS01820	COG2204	response regulator
J3U87_RS01825	COG1162	GTPase activity
J3U87_RS01840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J3U87_RS01870	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
J3U87_RS01890	COG0640	Transcriptional regulator
J3U87_RS01905	COG2070	2-Nitropropane dioxygenase
J3U87_RS01905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J3U87_RS01915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS01915	COG4221	oxidoreductase activity
J3U87_RS01915	COG3321	synthase
J3U87_RS01915	COG0300	oxidoreductase activity
J3U87_RS01920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS01920	COG4221	oxidoreductase activity
J3U87_RS01920	COG3321	synthase
J3U87_RS01920	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS01920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS01920	COG4221	oxidoreductase activity
J3U87_RS01920	COG3321	synthase
J3U87_RS01920	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS01925	COG0300	oxidoreductase activity
J3U87_RS01925	COG3321	synthase
J3U87_RS01925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS01925	COG4221	oxidoreductase activity
J3U87_RS01930	COG0500	methyltransferase
J3U87_RS01935	COG2272	Belongs to the type-B carboxylesterase lipase family
J3U87_RS01960	COG5183	chlorophyll binding
J3U87_RS01960	COG2133	pyrroloquinoline quinone binding
J3U87_RS01970	COG2815	serine threonine protein kinase
J3U87_RS01970	COG0515	serine threonine protein kinase
J3U87_RS01980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J3U87_RS02000	COG0612	Peptidase, M16
J3U87_RS02005	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J3U87_RS02010	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J3U87_RS02035	COG2223	nitrite transmembrane transporter activity
J3U87_RS02040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J3U87_RS02045	COG2146	nitrite reductase [NAD(P)H] activity
J3U87_RS02050	COG0243	molybdopterin cofactor binding
J3U87_RS02075	COG0076	glutamate decarboxylase activity
J3U87_RS02080	COG1819	glycosyl
J3U87_RS02095	COG3597	protein domain associated with
J3U87_RS02100	COG0824	Thioesterase
J3U87_RS02135	COG3292	Two component regulator propeller
J3U87_RS02135	COG2205	protein histidine kinase activity
J3U87_RS02135	COG0745	RESPONSE REGULATOR receiver
J3U87_RS02140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J3U87_RS02150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J3U87_RS02155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J3U87_RS02165	COG0629	single-stranded DNA binding
J3U87_RS02185	COG1388	LysM domain
J3U87_RS02185	COG0791	NLP P60 protein
J3U87_RS02205	COG0583	DNA-binding transcription factor activity
J3U87_RS02215	COG0058	SHG alpha-glucan phosphorylase activity
J3U87_RS02250	COG2819	hydrolase of the alpha beta superfamily
J3U87_RS02255	COG0572	uridine kinase
J3U87_RS02265	COG1846	Transcriptional regulator
J3U87_RS02295	COG3025	triphosphatase activity
J3U87_RS02300	COG0148	phosphopyruvate hydratase activity
J3U87_RS02305	COG0564	pseudouridine synthase activity
J3U87_RS02370	COG1446	asparaginase
J3U87_RS02380	COG1309	transcriptional regulator
J3U87_RS02385	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS02410	COG0463	Glycosyl transferase, family 2
J3U87_RS02455	COG1136	(ABC) transporter
J3U87_RS02475	COG3275	phosphorelay sensor kinase activity
J3U87_RS02480	COG3279	Response regulator of the LytR AlgR family
J3U87_RS02485	COG3852	Histidine kinase
J3U87_RS02490	COG2204	response regulator
J3U87_RS02525	COG3227	Zinc metalloprotease (Elastase)
J3U87_RS02560	COG4771	TonB-dependent receptor
J3U87_RS02565	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
J3U87_RS02605	COG0793	Belongs to the peptidase S41A family
J3U87_RS02615	COG0583	DNA-binding transcription factor activity
J3U87_RS02635	COG2815	serine threonine protein kinase
J3U87_RS02635	COG0515	serine threonine protein kinase
J3U87_RS02720	COG3501	Rhs element vgr protein
J3U87_RS02760	COG3275	phosphorelay sensor kinase activity
J3U87_RS02765	COG3279	Response regulator of the LytR AlgR family
J3U87_RS02810	COG1393	Belongs to the ArsC family
J3U87_RS02825	COG0417	DNA replication proofreading
J3U87_RS02840	COG0069	glutamate synthase activity
J3U87_RS02845	COG0702	epimerase
J3U87_RS02870	COG0189	ligase activity
J3U87_RS02875	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J3U87_RS02885	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J3U87_RS02890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J3U87_RS02900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J3U87_RS02905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J3U87_RS02925	COG0745	RESPONSE REGULATOR receiver
J3U87_RS02930	COG2815	serine threonine protein kinase
J3U87_RS02930	COG0515	serine threonine protein kinase
J3U87_RS02955	COG0583	DNA-binding transcription factor activity
J3U87_RS03005	COG1716	ATPase activity
J3U87_RS03005	COG1131	(ABC) transporter
J3U87_RS03005	COG0842	Transport permease protein
J3U87_RS03020	COG0501	Belongs to the peptidase M48B family
J3U87_RS03025	COG0393	Putative heavy-metal-binding
J3U87_RS03030	COG0393	Putative heavy-metal-binding
J3U87_RS03035	COG3938	Belongs to the proline racemase family
J3U87_RS03055	COG0405	Gamma-glutamyltransferase
J3U87_RS03065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J3U87_RS03075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J3U87_RS03080	COG3706	GGDEF domain
J3U87_RS03090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS03090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS03090	COG3321	synthase
J3U87_RS03090	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS03090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS03100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J3U87_RS03115	COG0681	Belongs to the peptidase S26 family
J3U87_RS03125	COG0860	N-Acetylmuramoyl-L-alanine amidase
J3U87_RS03130	COG2885	chlorophyll binding
J3U87_RS03145	COG0745	RESPONSE REGULATOR receiver
J3U87_RS03155	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J3U87_RS03160	COG1136	(ABC) transporter
J3U87_RS03165	COG0577	efflux transmembrane transporter activity
J3U87_RS03165	COG1136	(ABC) transporter
J3U87_RS03170	COG1136	(ABC) transporter
J3U87_RS03170	COG0577	efflux transmembrane transporter activity
J3U87_RS03175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3U87_RS03215	COG0443	Heat shock 70 kDa protein
J3U87_RS03270	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J3U87_RS03280	COG0515	serine threonine protein kinase
J3U87_RS03290	COG0739	heme binding
J3U87_RS03295	COG0653	protein targeting
J3U87_RS03300	COG0516	GMP reductase activity
J3U87_RS03300	COG0517	IMP dehydrogenase activity
J3U87_RS03315	COG3119	arylsulfatase activity
J3U87_RS03335	COG4771	TonB-dependent receptor
J3U87_RS03340	COG3290	protein histidine kinase activity
J3U87_RS03345	COG2814	Major facilitator Superfamily
J3U87_RS03365	COG0572	uridine kinase
J3U87_RS03370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J3U87_RS03385	COG1012	belongs to the aldehyde dehydrogenase family
J3U87_RS03390	COG2084	Dehydrogenase
J3U87_RS03395	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS03400	COG1063	alcohol dehydrogenase
J3U87_RS03410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J3U87_RS03435	COG0646	methionine synthase
J3U87_RS03435	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J3U87_RS03440	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J3U87_RS03445	COG2819	hydrolase of the alpha beta superfamily
J3U87_RS03455	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J3U87_RS03465	COG2815	serine threonine protein kinase
J3U87_RS03465	COG0515	serine threonine protein kinase
J3U87_RS03495	COG2832	Protein of unknown function (DUF454)
J3U87_RS03515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS03515	COG4221	oxidoreductase activity
J3U87_RS03515	COG0300	oxidoreductase activity
J3U87_RS03515	COG3321	synthase
J3U87_RS03520	COG0076	glutamate decarboxylase activity
J3U87_RS03565	COG1063	alcohol dehydrogenase
J3U87_RS03610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J3U87_RS03635	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
J3U87_RS03640	COG0733	neurotransmitter:sodium symporter activity
J3U87_RS03650	COG1012	belongs to the aldehyde dehydrogenase family
J3U87_RS03660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS03700	COG1309	transcriptional regulator
J3U87_RS03705	COG1132	(ABC) transporter
J3U87_RS03735	COG0784	Response regulator, receiver
J3U87_RS03735	COG5002	protein histidine kinase activity
J3U87_RS03740	COG0784	Response regulator, receiver
J3U87_RS03745	COG2201	protein-glutamate methylesterase activity
J3U87_RS03750	COG4251	negative regulation of phosphorylation
J3U87_RS03755	COG0583	DNA-binding transcription factor activity
J3U87_RS03760	COG0631	protein serine/threonine phosphatase activity
J3U87_RS03770	COG0625	glutathione transferase activity
J3U87_RS03800	COG0643	Histidine kinase
J3U87_RS03800	COG2198	Histidine kinase
J3U87_RS03810	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J3U87_RS03840	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS03850	COG0395	ABC-type sugar transport system, permease component
J3U87_RS03855	COG3842	ATPase activity
J3U87_RS03870	COG2264	protein methyltransferase activity
J3U87_RS03875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J3U87_RS03890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3U87_RS03895	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J3U87_RS03900	COG2050	protein possibly involved in aromatic compounds catabolism
J3U87_RS03905	COG0484	heat shock protein binding
J3U87_RS03915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J3U87_RS03940	COG1404	Belongs to the peptidase S8 family
J3U87_RS03945	COG0564	pseudouridine synthase activity
J3U87_RS03950	COG0784	Response regulator, receiver
J3U87_RS03950	COG2205	protein histidine kinase activity
J3U87_RS03960	COG1881	PFAM PEBP family protein
J3U87_RS03970	COG1324	tolerance protein
J3U87_RS03990	COG3344	reverse transcriptase
J3U87_RS04000	COG0728	peptidoglycan biosynthetic process
J3U87_RS04005	COG0800	Aldolase
J3U87_RS04010	COG0837	glucose binding
J3U87_RS04020	COG0363	glucosamine-6-phosphate deaminase activity
J3U87_RS04025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J3U87_RS04035	COG0583	DNA-binding transcription factor activity
J3U87_RS04045	COG1942	4-Oxalocrotonate Tautomerase
J3U87_RS04055	COG4555	ABC transporter
J3U87_RS04065	COG3708	Transcriptional regulator
J3U87_RS04065	COG2207	Transcriptional regulator
J3U87_RS04080	COG0681	Belongs to the peptidase S26 family
J3U87_RS04090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J3U87_RS04095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J3U87_RS04100	COG1595	DNA-templated transcription, initiation
J3U87_RS04135	COG0515	serine threonine protein kinase
J3U87_RS04135	COG2815	serine threonine protein kinase
J3U87_RS04140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS04230	COG1331	Highly conserved protein containing a thioredoxin domain
J3U87_RS04260	COG3227	Zinc metalloprotease (Elastase)
J3U87_RS04265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J3U87_RS04275	COG1160	GTP binding
J3U87_RS04320	COG4772	TonB-dependent receptor
J3U87_RS04335	COG0625	glutathione transferase activity
J3U87_RS04355	COG0318	PFAM AMP-dependent synthetase and ligase
J3U87_RS04360	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J3U87_RS04370	COG0243	molybdopterin cofactor binding
J3U87_RS04375	COG0515	serine threonine protein kinase
J3U87_RS04375	COG2815	serine threonine protein kinase
J3U87_RS04380	COG0745	RESPONSE REGULATOR receiver
J3U87_RS04380	COG2205	protein histidine kinase activity
J3U87_RS04380	COG3292	Two component regulator propeller
J3U87_RS04395	COG2124	cytochrome p450
J3U87_RS04405	COG0789	Transcriptional regulator
J3U87_RS04415	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J3U87_RS04425	COG0515	serine threonine protein kinase
J3U87_RS04425	COG0457	Tetratricopeptide repeat
J3U87_RS04440	COG2815	serine threonine protein kinase
J3U87_RS04440	COG0515	serine threonine protein kinase
J3U87_RS04465	COG0515	serine threonine protein kinase
J3U87_RS04465	COG2815	serine threonine protein kinase
J3U87_RS04520	COG5002	protein histidine kinase activity
J3U87_RS04535	COG2205	protein histidine kinase activity
J3U87_RS04635	COG0515	serine threonine protein kinase
J3U87_RS04635	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J3U87_RS04640	COG3227	Zinc metalloprotease (Elastase)
J3U87_RS04655	COG0640	Transcriptional regulator
J3U87_RS04685	COG0745	RESPONSE REGULATOR receiver
J3U87_RS04690	COG2205	protein histidine kinase activity
J3U87_RS04705	COG3437	response regulator, receiver
J3U87_RS04710	COG0784	Response regulator, receiver
J3U87_RS04710	COG2198	Histidine kinase
J3U87_RS04710	COG2205	protein histidine kinase activity
J3U87_RS04715	COG5002	protein histidine kinase activity
J3U87_RS04720	COG1744	ABC transporter substrate-binding protein PnrA-like
J3U87_RS04725	COG1181	Belongs to the D-alanine--D-alanine ligase family
J3U87_RS04740	COG0506	proline dehydrogenase activity
J3U87_RS04790	COG2319	Wd-40 repeat
J3U87_RS04790	COG4249	Peptidase C14 caspase catalytic subunit p20
J3U87_RS04810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J3U87_RS04815	COG0408	coproporphyrinogen oxidase activity
J3U87_RS04820	COG2363	Small membrane protein
J3U87_RS04840	COG3604	Transcriptional regulator
J3U87_RS04845	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J3U87_RS04850	COG0450	alkyl hydroperoxide reductase
J3U87_RS04870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J3U87_RS04885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J3U87_RS04915	COG1595	DNA-templated transcription, initiation
J3U87_RS05040	COG2433	Pfam Transposase IS66
J3U87_RS05045	COG1309	transcriptional regulator
J3U87_RS05080	COG1132	(ABC) transporter
J3U87_RS05090	COG4774	siderophore transport
J3U87_RS05125	COG4771	TonB-dependent receptor
J3U87_RS05130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J3U87_RS05135	COG3459	Glycosyltransferase 36 associated
J3U87_RS05140	COG3291	Pkd domain containing protein
J3U87_RS05210	COG0583	DNA-binding transcription factor activity
J3U87_RS05230	COG3706	GGDEF domain
J3U87_RS05235	COG2815	serine threonine protein kinase
J3U87_RS05235	COG0515	serine threonine protein kinase
J3U87_RS05255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J3U87_RS05285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J3U87_RS05340	COG4585	Histidine kinase
J3U87_RS05345	COG2197	response regulator
J3U87_RS05360	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J3U87_RS05365	COG0745	RESPONSE REGULATOR receiver
J3U87_RS05375	COG0587	DNA-directed DNA polymerase activity
J3U87_RS05380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J3U87_RS05385	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J3U87_RS05400	COG4191	Histidine kinase
J3U87_RS05460	COG4935	Belongs to the peptidase S8 family
J3U87_RS05460	COG1404	Belongs to the peptidase S8 family
J3U87_RS05495	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J3U87_RS05500	COG0277	FAD linked oxidase domain protein
J3U87_RS05505	COG0277	FAD linked oxidase domain protein
J3U87_RS05510	COG0247	lactate metabolic process
J3U87_RS05550	COG0515	serine threonine protein kinase
J3U87_RS05550	COG2815	serine threonine protein kinase
J3U87_RS05585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J3U87_RS05620	COG0501	Belongs to the peptidase M48B family
J3U87_RS05645	COG3710	Transcriptional regulator
J3U87_RS05650	COG1131	(ABC) transporter
J3U87_RS05655	COG0842	Transport permease protein
J3U87_RS05660	COG2066	Belongs to the glutaminase family
J3U87_RS05665	COG0515	serine threonine protein kinase
J3U87_RS05665	COG2815	serine threonine protein kinase
J3U87_RS05670	COG0750	zinc metalloprotease
J3U87_RS05675	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J3U87_RS05680	COG0205	6-phosphofructokinase activity
J3U87_RS05695	COG0572	uridine kinase
J3U87_RS05705	COG1100	Small GTP-binding protein
J3U87_RS05730	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J3U87_RS05730	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J3U87_RS05735	COG0501	Belongs to the peptidase M48B family
J3U87_RS05785	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J3U87_RS05800	COG0405	Gamma-glutamyltransferase
J3U87_RS05840	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J3U87_RS05840	COG0517	IMP dehydrogenase activity
J3U87_RS05845	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J3U87_RS05850	COG0504	CTP synthase activity
J3U87_RS05855	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J3U87_RS05860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J3U87_RS05865	COG0741	lytic transglycosylase activity
J3U87_RS05875	COG0217	transcriptional regulatory protein
J3U87_RS05885	COG3588	fructose-bisphosphate aldolase
J3U87_RS05895	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J3U87_RS05900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J3U87_RS05975	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J3U87_RS05980	COG1923	regulation of RNA biosynthetic process
J3U87_RS05995	COG2353	YceI-like domain
J3U87_RS06015	COG3360	Dodecin
J3U87_RS06020	COG1404	Belongs to the peptidase S8 family
J3U87_RS06065	COG1815	bacterial-type flagellum-dependent cell motility
J3U87_RS06070	COG1558	bacterial-type flagellum-dependent cell motility
J3U87_RS06075	COG1677	Flagellar hook-basal body complex protein FliE
J3U87_RS06085	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J3U87_RS06095	COG1157	protein secretion by the type III secretion system
J3U87_RS06200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3U87_RS06230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J3U87_RS06235	COG0626	cystathionine gamma-synthase activity
J3U87_RS06250	COG1404	Belongs to the peptidase S8 family
J3U87_RS06255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J3U87_RS06260	COG0724	RNA recognition motif
J3U87_RS06275	COG3501	Rhs element vgr protein
J3U87_RS06305	COG3011	Protein conserved in bacteria
J3U87_RS06310	COG0784	Response regulator, receiver
J3U87_RS06310	COG2205	protein histidine kinase activity
J3U87_RS06310	COG5002	protein histidine kinase activity
J3U87_RS06315	COG2135	peptidase activity
J3U87_RS06320	COG0519	Catalyzes the synthesis of GMP from XMP
J3U87_RS06320	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J3U87_RS06385	COG1194	a g-specific adenine glycosylase
J3U87_RS06405	COG2766	serine protein kinase
J3U87_RS06415	COG1022	Amp-dependent synthetase and ligase
J3U87_RS06425	COG1280	lysine exporter protein (LysE YggA)
J3U87_RS06445	COG0525	valine-tRNA ligase activity
J3U87_RS06485	COG4974	Belongs to the 'phage' integrase family
J3U87_RS06490	COG4974	Belongs to the 'phage' integrase family
J3U87_RS06515	COG0582	viral genome integration into host DNA
J3U87_RS06530	COG0395	ABC-type sugar transport system, permease component
J3U87_RS06545	COG3842	ATPase activity
J3U87_RS06555	COG0297	glycogen (starch) synthase activity
J3U87_RS06560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J3U87_RS06565	COG2356	endonuclease I
J3U87_RS06570	COG5002	protein histidine kinase activity
J3U87_RS06570	COG2205	protein histidine kinase activity
J3U87_RS06570	COG0784	Response regulator, receiver
J3U87_RS06580	COG1960	acyl-CoA dehydrogenase activity
J3U87_RS06585	COG4948	Mandelate Racemase Muconate Lactonizing
J3U87_RS06600	COG3209	COG3209 Rhs family protein
J3U87_RS06605	COG4535	Mg2 and Co2 transporter CorC
J3U87_RS06610	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J3U87_RS06620	COG0492	ferredoxin-NADP+ reductase activity
J3U87_RS06635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J3U87_RS06665	COG2827	Endonuclease containing a URI domain
J3U87_RS06675	COG0473	3-isopropylmalate dehydrogenase activity
J3U87_RS06680	COG0066	3-isopropylmalate dehydratase activity
J3U87_RS06685	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J3U87_RS06690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J3U87_RS06765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J3U87_RS06775	COG2815	serine threonine protein kinase
J3U87_RS06775	COG0515	serine threonine protein kinase
J3U87_RS06785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J3U87_RS06790	COG0527	aspartate kinase activity
J3U87_RS06795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J3U87_RS06805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J3U87_RS06830	COG0523	cobalamin synthesis protein
J3U87_RS06850	COG0793	Belongs to the peptidase S41A family
J3U87_RS06865	COG0745	RESPONSE REGULATOR receiver
J3U87_RS06900	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J3U87_RS06935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J3U87_RS06940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J3U87_RS06965	COG4864	UPF0365 protein
J3U87_RS06975	COG1030	water channel activity
J3U87_RS06980	COG2890	protein-(glutamine-N5) methyltransferase activity
J3U87_RS06985	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J3U87_RS06995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J3U87_RS07000	COG0617	tRNA 3'-terminal CCA addition
J3U87_RS07015	COG0268	Binds directly to 16S ribosomal RNA
J3U87_RS07025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J3U87_RS07030	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J3U87_RS07035	COG1960	acyl-CoA dehydrogenase activity
J3U87_RS07045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J3U87_RS07050	COG1639	'signal transduction protein
J3U87_RS07055	COG1418	mRNA catabolic process
J3U87_RS07070	COG3604	Transcriptional regulator
J3U87_RS07105	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J3U87_RS07115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J3U87_RS07135	COG0242	peptide deformylase activity
J3U87_RS07140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J3U87_RS07150	COG0745	RESPONSE REGULATOR receiver
J3U87_RS07150	COG2205	protein histidine kinase activity
J3U87_RS07150	COG3292	Two component regulator propeller
J3U87_RS07155	COG0709	Synthesizes selenophosphate from selenide and ATP
J3U87_RS07175	COG1131	(ABC) transporter
J3U87_RS07195	COG3597	protein domain associated with
J3U87_RS07205	COG0154	amidase activity
J3U87_RS07235	COG3321	synthase
J3U87_RS07235	COG0604	alcohol dehydrogenase
J3U87_RS07250	COG0667	Aldo Keto reductase
J3U87_RS07255	COG0037	tRNA processing
J3U87_RS07270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS07350	COG0247	lactate metabolic process
J3U87_RS07350	COG2181	nitrate reductase activity
J3U87_RS07370	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
J3U87_RS07390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J3U87_RS07455	COG0471	metal ion transport
J3U87_RS07485	COG2770	Histidine kinase
J3U87_RS07485	COG2205	protein histidine kinase activity
J3U87_RS07490	COG0784	Response regulator, receiver
J3U87_RS07490	COG2205	protein histidine kinase activity
J3U87_RS07495	COG0129	dihydroxy-acid dehydratase activity
J3U87_RS07500	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J3U87_RS07510	COG3978	acetolactate synthase activity
J3U87_RS07515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J3U87_RS07550	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J3U87_RS07585	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS07620	COG0745	RESPONSE REGULATOR receiver
J3U87_RS07660	COG1404	Belongs to the peptidase S8 family
J3U87_RS07670	COG0420	3'-5' exonuclease activity
J3U87_RS07685	COG3568	Endonuclease Exonuclease Phosphatase
J3U87_RS07720	COG1022	Amp-dependent synthetase and ligase
J3U87_RS07745	COG4152	abc transporter atp-binding protein
J3U87_RS07755	COG1032	radical SAM domain protein
J3U87_RS07790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
J3U87_RS07815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J3U87_RS07820	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J3U87_RS07825	COG3185	4-Hydroxyphenylpyruvate dioxygenase
J3U87_RS07830	COG1522	sequence-specific DNA binding
J3U87_RS07850	COG2986	histidine ammonia-lyase
J3U87_RS07860	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS07865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J3U87_RS07900	COG2205	protein histidine kinase activity
J3U87_RS07905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J3U87_RS07915	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J3U87_RS07920	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J3U87_RS07925	COG3119	arylsulfatase activity
J3U87_RS07930	COG1324	tolerance protein
J3U87_RS07935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J3U87_RS07955	COG1960	acyl-CoA dehydrogenase activity
J3U87_RS07970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J3U87_RS08015	COG0515	serine threonine protein kinase
J3U87_RS08015	COG2815	serine threonine protein kinase
J3U87_RS08025	COG4191	Histidine kinase
J3U87_RS08050	COG0714	Associated with various cellular activities
J3U87_RS08080	COG1776	CheC inhibitor of MCP methylation
J3U87_RS08080	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J3U87_RS08085	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J3U87_RS08090	COG1191	sigma factor activity
J3U87_RS08100	COG1419	protein localization to endoplasmic reticulum
J3U87_RS08105	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J3U87_RS08110	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J3U87_RS08115	COG1684	flagellar biosynthetic protein fliR
J3U87_RS08120	COG1987	bacterial-type flagellum assembly
J3U87_RS08125	COG1338	Plays a role in the flagellum-specific transport system
J3U87_RS08135	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J3U87_RS08185	COG0534	Mate efflux family protein
J3U87_RS08195	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J3U87_RS08200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J3U87_RS08215	COG2080	2 iron, 2 sulfur cluster binding
J3U87_RS08235	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J3U87_RS08245	COG0402	S-adenosylhomocysteine deaminase activity
J3U87_RS08260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J3U87_RS08265	COG0641	radical SAM
J3U87_RS08270	COG1104	cysteine desulfurase activity
J3U87_RS08275	COG0509	glycine decarboxylation via glycine cleavage system
J3U87_RS08340	COG0745	RESPONSE REGULATOR receiver
J3U87_RS08410	COG2267	carboxylic ester hydrolase activity
J3U87_RS08425	COG0604	alcohol dehydrogenase
J3U87_RS08425	COG3321	synthase
J3U87_RS08430	COG2226	methyltransferase
J3U87_RS08465	COG2204	response regulator
J3U87_RS08485	COG3279	Response regulator of the LytR AlgR family
J3U87_RS08500	COG0439	Biotin carboxylase
J3U87_RS08515	COG0546	phosphoglycolate phosphatase activity
J3U87_RS08520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J3U87_RS08530	COG2267	carboxylic ester hydrolase activity
J3U87_RS08560	COG0745	RESPONSE REGULATOR receiver
J3U87_RS08560	COG2205	protein histidine kinase activity
J3U87_RS08560	COG3292	Two component regulator propeller
J3U87_RS08565	COG2197	response regulator
J3U87_RS08580	COG1994	Peptidase M50
J3U87_RS08590	COG0793	Belongs to the peptidase S41A family
J3U87_RS08590	COG4946	Tricorn protease homolog
J3U87_RS08600	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS08605	COG3132	Protein of unknown function, DUF480
J3U87_RS08610	COG0515	serine threonine protein kinase
J3U87_RS08610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J3U87_RS08655	COG2815	serine threonine protein kinase
J3U87_RS08655	COG0515	serine threonine protein kinase
J3U87_RS08670	COG1051	belongs to the nudix hydrolase family
J3U87_RS08690	COG0475	glutathione-regulated potassium exporter activity
J3U87_RS08710	COG0604	alcohol dehydrogenase
J3U87_RS08710	COG3321	synthase
J3U87_RS08715	COG3321	synthase
J3U87_RS08715	COG0604	alcohol dehydrogenase
J3U87_RS08720	COG3321	synthase
J3U87_RS08720	COG0604	alcohol dehydrogenase
J3U87_RS08730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J3U87_RS08735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J3U87_RS08735	COG4191	Histidine kinase
J3U87_RS08740	COG0784	Response regulator, receiver
J3U87_RS08740	COG3437	response regulator, receiver
J3U87_RS08765	COG1842	Phage shock protein A
J3U87_RS08775	COG0714	Associated with various cellular activities
J3U87_RS08825	COG0535	radical SAM domain protein
J3U87_RS08830	COG1132	(ABC) transporter
J3U87_RS08845	COG4953	penicillin-binding protein 1C
J3U87_RS08855	COG3217	Mosc domain protein beta barrel domain protein
J3U87_RS08855	COG0633	Ferredoxin
J3U87_RS08865	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J3U87_RS08875	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J3U87_RS08875	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J3U87_RS08880	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J3U87_RS08885	COG0228	four-way junction DNA binding
J3U87_RS08895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J3U87_RS08900	COG0336	Belongs to the RNA methyltransferase TrmD family
J3U87_RS08905	COG4752	Belongs to the RNA methyltransferase TrmD family
J3U87_RS08910	COG0335	large ribosomal subunit rRNA binding
J3U87_RS08920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J3U87_RS08925	COG0346	lactoylglutathione lyase activity
J3U87_RS08935	COG1404	Belongs to the peptidase S8 family
J3U87_RS08975	COG0542	response to heat
J3U87_RS08990	COG4771	TonB-dependent receptor
J3U87_RS08995	COG2333	competence protein COMEC
J3U87_RS08995	COG0658	competence protein
J3U87_RS09020	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J3U87_RS09025	COG4974	Belongs to the 'phage' integrase family
J3U87_RS09065	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J3U87_RS09070	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J3U87_RS09070	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J3U87_RS09095	COG0442	prolyl-tRNA aminoacylation
J3U87_RS09105	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J3U87_RS09110	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J3U87_RS09125	COG0210	DNA helicase
J3U87_RS09135	COG0745	RESPONSE REGULATOR receiver
J3U87_RS09140	COG1100	Small GTP-binding protein
J3U87_RS09145	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
J3U87_RS09150	COG0280	phosphate acetyltransferase
J3U87_RS09155	COG2094	Belongs to the DNA glycosylase MPG family
J3U87_RS09160	COG2815	serine threonine protein kinase
J3U87_RS09160	COG0515	serine threonine protein kinase
J3U87_RS09185	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J3U87_RS09205	COG4134	Bacterial extracellular solute-binding protein
J3U87_RS09245	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J3U87_RS09250	COG0488	(ABC) transporter
J3U87_RS09255	COG0742	ribosomal rna small subunit methyltransferase
J3U87_RS09265	COG2885	chlorophyll binding
J3U87_RS09270	COG0823	Involved in the tonB-independent uptake of proteins
J3U87_RS09285	COG0811	peptide transport
J3U87_RS09290	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J3U87_RS09295	COG0497	DNA recombination
J3U87_RS09300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J3U87_RS09320	COG0359	binds to the 23S rRNA
J3U87_RS09325	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J3U87_RS09335	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J3U87_RS09340	COG3710	Transcriptional regulator
J3U87_RS09360	COG5002	protein histidine kinase activity
J3U87_RS09370	COG0346	lactoylglutathione lyase activity
J3U87_RS09375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J3U87_RS09390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J3U87_RS09395	COG1201	RNA secondary structure unwinding
J3U87_RS09425	COG0616	signal peptide processing
J3U87_RS09435	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J3U87_RS09440	COG0708	Exodeoxyribonuclease III
J3U87_RS09470	COG1519	Transferase
J3U87_RS09475	COG0825	malonyl-CoA metabolic process
J3U87_RS09480	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J3U87_RS09480	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
J3U87_RS09490	COG1137	ATPase activity
J3U87_RS09495	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J3U87_RS09500	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J3U87_RS09505	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J3U87_RS09545	COG0835	chemotaxis
J3U87_RS09545	COG0784	Response regulator, receiver
J3U87_RS09555	COG2205	protein histidine kinase activity
J3U87_RS09560	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J3U87_RS09570	COG3001	Fructosamine kinase
J3U87_RS09580	COG0028	Belongs to the TPP enzyme family
J3U87_RS09585	COG0492	ferredoxin-NADP+ reductase activity
J3U87_RS09605	COG0142	geranyltranstransferase activity
J3U87_RS09610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J3U87_RS09620	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
J3U87_RS09625	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J3U87_RS09635	COG2234	aminopeptidase activity
J3U87_RS09640	COG1492	cobalamin metabolic process
J3U87_RS09670	COG0739	heme binding
J3U87_RS09670	COG0741	lytic transglycosylase activity
J3U87_RS09670	COG1196	nuclear chromosome segregation
J3U87_RS09675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J3U87_RS09680	COG2166	iron-sulfur cluster assembly
J3U87_RS09710	COG0859	PFAM glycosyl transferase family 9
J3U87_RS09715	COG0859	PFAM glycosyl transferase family 9
J3U87_RS09720	COG1420	regulation of RNA biosynthetic process
J3U87_RS09725	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J3U87_RS09730	COG0443	Heat shock 70 kDa protein
J3U87_RS09735	COG0484	heat shock protein binding
J3U87_RS09740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J3U87_RS09755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J3U87_RS09760	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J3U87_RS09765	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J3U87_RS09785	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J3U87_RS09795	COG0564	pseudouridine synthase activity
J3U87_RS09800	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
J3U87_RS09810	COG0745	RESPONSE REGULATOR receiver
J3U87_RS09830	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J3U87_RS09835	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J3U87_RS09840	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J3U87_RS09845	COG0740	serine-type endopeptidase activity
J3U87_RS09850	COG0544	peptidyl-prolyl cis-trans isomerase activity
J3U87_RS09880	COG1509	lysine 2,3-aminomutase activity
J3U87_RS09900	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J3U87_RS09905	COG1074	ATP-dependent DNA helicase activity
J3U87_RS09920	COG0545	Peptidyl-prolyl cis-trans isomerase
J3U87_RS09930	COG0004	ammonium transporteR
J3U87_RS09935	COG0070	glutamate synthase
J3U87_RS09935	COG0067	glutamate synthase
J3U87_RS09935	COG0069	glutamate synthase activity
J3U87_RS09940	COG2274	protein secretion by the type I secretion system
J3U87_RS09970	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J3U87_RS09990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J3U87_RS10025	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
J3U87_RS10045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J3U87_RS10065	COG1595	DNA-templated transcription, initiation
J3U87_RS10075	COG0564	pseudouridine synthase activity
J3U87_RS10100	COG3279	Response regulator of the LytR AlgR family
J3U87_RS10105	COG2972	Histidine kinase
J3U87_RS10110	COG1136	(ABC) transporter
J3U87_RS10125	COG1611	Belongs to the LOG family
J3U87_RS10140	COG0481	GTPase activity
J3U87_RS10145	COG1132	(ABC) transporter
J3U87_RS10150	COG0166	Belongs to the GPI family
J3U87_RS10155	COG2226	methyltransferase
J3U87_RS10170	COG2205	protein histidine kinase activity
J3U87_RS10170	COG0745	RESPONSE REGULATOR receiver
J3U87_RS10170	COG3292	Two component regulator propeller
J3U87_RS10180	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
J3U87_RS10190	COG0443	Heat shock 70 kDa protein
J3U87_RS10195	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J3U87_RS10200	COG0484	heat shock protein binding
J3U87_RS10225	COG0367	asparagine synthase
J3U87_RS10250	COG0156	8-amino-7-oxononanoate synthase activity
J3U87_RS10255	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J3U87_RS10275	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J3U87_RS10280	COG1663	tetraacyldisaccharide 4'-kinase activity
J3U87_RS10285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J3U87_RS10290	COG0646	methionine synthase
J3U87_RS10290	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J3U87_RS10300	COG0552	protein localization to endoplasmic reticulum
J3U87_RS10335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J3U87_RS10350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J3U87_RS10355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J3U87_RS10360	COG0758	DNA mediated transformation
J3U87_RS10380	COG2226	methyltransferase
J3U87_RS10390	COG1757	Na H antiporter
J3U87_RS10400	COG0095	Lipoate-protein ligase
J3U87_RS10405	COG0686	Belongs to the AlaDH PNT family
J3U87_RS10425	COG0488	(ABC) transporter
J3U87_RS10470	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS10470	COG3347	Dehydrogenase
J3U87_RS10510	COG1757	Na H antiporter
J3U87_RS10520	COG4249	Peptidase C14 caspase catalytic subunit p20
J3U87_RS10520	COG2319	Wd-40 repeat
J3U87_RS10525	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J3U87_RS10560	COG3586	endonuclease activity
J3U87_RS10570	COG1446	asparaginase
J3U87_RS10615	COG0745	RESPONSE REGULATOR receiver
J3U87_RS10620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J3U87_RS10625	COG0085	RNA polymerase activity
J3U87_RS10630	COG0222	ribosome binding
J3U87_RS10635	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J3U87_RS10645	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J3U87_RS10650	COG0250	Participates in transcription elongation, termination and antitermination
J3U87_RS10665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J3U87_RS10700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J3U87_RS10725	COG2815	serine threonine protein kinase
J3U87_RS10725	COG0515	serine threonine protein kinase
J3U87_RS10740	COG0463	Glycosyl transferase, family 2
J3U87_RS10750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J3U87_RS10785	COG0512	Glutamine amidotransferase of anthranilate synthase
J3U87_RS10790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J3U87_RS10805	COG0616	signal peptide processing
J3U87_RS10810	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
J3U87_RS10825	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J3U87_RS10830	COG0360	Binds together with S18 to 16S ribosomal RNA
J3U87_RS10835	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J3U87_RS10840	COG0193	aminoacyl-tRNA hydrolase activity
J3U87_RS10845	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J3U87_RS10850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J3U87_RS10860	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J3U87_RS10875	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J3U87_RS10890	COG0667	Aldo Keto reductase
J3U87_RS10895	COG1136	(ABC) transporter
J3U87_RS10915	COG4771	TonB-dependent receptor
J3U87_RS10945	COG2304	oxidoreductase activity
J3U87_RS10975	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J3U87_RS10985	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J3U87_RS10990	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J3U87_RS11025	COG1131	(ABC) transporter
J3U87_RS11035	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J3U87_RS11035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J3U87_RS11040	COG0745	RESPONSE REGULATOR receiver
J3U87_RS11050	COG2894	cell division
J3U87_RS11080	COG3852	Histidine kinase
J3U87_RS11090	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J3U87_RS11100	COG2204	response regulator
J3U87_RS11105	COG4191	Histidine kinase
J3U87_RS11110	COG1459	type II secretion system
J3U87_RS11120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J3U87_RS11125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J3U87_RS11130	COG0439	Biotin carboxylase
J3U87_RS11185	COG0484	heat shock protein binding
J3U87_RS11210	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
J3U87_RS11235	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS11255	COG0109	protoheme IX farnesyltransferase activity
J3U87_RS11265	COG3101	peptidyl-lysine hydroxylation
J3U87_RS11270	COG1217	gtp-binding protein TYPA
J3U87_RS11275	COG0011	TIGRFAM Protein of
J3U87_RS11280	COG1515	deoxyribonuclease V activity
J3U87_RS11295	COG0515	serine threonine protein kinase
J3U87_RS11295	COG2815	serine threonine protein kinase
J3U87_RS11305	COG0233	cytoplasmic translational termination
J3U87_RS11310	COG0528	UMP kinase activity
J3U87_RS11315	COG0012	GTP binding
J3U87_RS11320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J3U87_RS11330	COG0745	RESPONSE REGULATOR receiver
J3U87_RS11335	COG0303	'Molybdopterin
J3U87_RS11365	COG0488	(ABC) transporter
J3U87_RS11380	COG1760	l-serine dehydratase
J3U87_RS11385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J3U87_RS11390	COG0473	3-isopropylmalate dehydrogenase activity
J3U87_RS11430	COG0137	argininosuccinate synthase activity
J3U87_RS11435	COG0165	Argininosuccinate lyase
J3U87_RS11445	COG0745	RESPONSE REGULATOR receiver
J3U87_RS11465	COG2204	response regulator
J3U87_RS11480	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J3U87_RS11485	COG1185	polyribonucleotide nucleotidyltransferase activity
J3U87_RS11510	COG2986	histidine ammonia-lyase
J3U87_RS11515	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J3U87_RS11515	COG0674	pyruvate-flavodoxin oxidoreductase activity
J3U87_RS11520	COG1013	pyruvate-flavodoxin oxidoreductase activity
J3U87_RS11525	COG0784	Response regulator, receiver
J3U87_RS11525	COG4191	Histidine kinase
J3U87_RS11560	COG0180	Tryptophanyl-tRNA synthetase
J3U87_RS11565	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
J3U87_RS11570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J3U87_RS11585	COG1012	belongs to the aldehyde dehydrogenase family
J3U87_RS11600	COG1595	DNA-templated transcription, initiation
J3U87_RS11615	COG0702	epimerase
J3U87_RS11625	COG0717	Belongs to the dCTP deaminase family
J3U87_RS11635	COG1530	ribonuclease E activity
J3U87_RS11640	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J3U87_RS11645	COG0047	phosphoribosylformylglycinamidine synthase activity
J3U87_RS11660	COG0356	it plays a direct role in the translocation of protons across the membrane
J3U87_RS11665	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J3U87_RS11695	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
J3U87_RS11700	COG1183	phosphatidylcholine synthase activity
J3U87_RS11710	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J3U87_RS11715	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J3U87_RS11740	COG0577	efflux transmembrane transporter activity
J3U87_RS11740	COG1136	(ABC) transporter
J3U87_RS11745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J3U87_RS11780	COG2252	PERMEase
J3U87_RS11800	COG1716	ATPase activity
J3U87_RS11800	COG1131	(ABC) transporter
J3U87_RS11800	COG0842	Transport permease protein
J3U87_RS11810	COG0515	serine threonine protein kinase
J3U87_RS11810	COG2815	serine threonine protein kinase
J3U87_RS11830	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J3U87_RS11840	COG1104	cysteine desulfurase activity
J3U87_RS11845	COG0142	geranyltranstransferase activity
J3U87_RS11850	COG1722	exodeoxyribonuclease VII activity
J3U87_RS11855	COG1570	exodeoxyribonuclease VII activity
J3U87_RS11860	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J3U87_RS11865	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J3U87_RS11895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J3U87_RS11895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J3U87_RS11910	COG3279	Response regulator of the LytR AlgR family
J3U87_RS11915	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
J3U87_RS11915	COG0778	Nitroreductase
J3U87_RS11920	COG3292	Two component regulator propeller
J3U87_RS11920	COG0745	RESPONSE REGULATOR receiver
J3U87_RS11920	COG2205	protein histidine kinase activity
J3U87_RS11925	COG2226	methyltransferase
J3U87_RS11950	COG1805	sodium ion transport
J3U87_RS11955	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J3U87_RS11965	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J3U87_RS11970	COG2871	sodium ion transport
J3U87_RS12015	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J3U87_RS12025	COG0322	excinuclease ABC activity
J3U87_RS12035	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J3U87_RS12045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J3U87_RS12050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J3U87_RS12065	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
J3U87_RS12080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J3U87_RS12090	COG5002	protein histidine kinase activity
J3U87_RS12095	COG0745	RESPONSE REGULATOR receiver
J3U87_RS12120	COG0084	hydrolase, TatD family'
J3U87_RS12140	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J3U87_RS12145	COG0688	phosphatidylethanolamine metabolic process
J3U87_RS12155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J3U87_RS12160	COG1755	Isoprenylcysteine carboxyl methyltransferase
J3U87_RS12185	COG0732	type I restriction modification DNA specificity domain
J3U87_RS12225	COG0259	pyridoxamine-phosphate oxidase activity
J3U87_RS12230	COG2962	Rard protein
J3U87_RS12235	COG0438	transferase activity, transferring glycosyl groups
J3U87_RS12255	COG0583	DNA-binding transcription factor activity
J3U87_RS12260	COG0745	RESPONSE REGULATOR receiver
J3U87_RS12265	COG0784	Response regulator, receiver
J3U87_RS12270	COG0802	atpase or kinase
J3U87_RS12275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J3U87_RS12275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J3U87_RS12295	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J3U87_RS12300	COG0515	serine threonine protein kinase
J3U87_RS12310	COG3604	Transcriptional regulator
J3U87_RS12330	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J3U87_RS12330	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J3U87_RS12335	COG1703	isobutyryl-CoA mutase activity
J3U87_RS12350	COG0573	inorganic phosphate transmembrane transporter activity
J3U87_RS12355	COG0581	inorganic phosphate transmembrane transporter activity
J3U87_RS12360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J3U87_RS12365	COG0704	Plays a role in the regulation of phosphate uptake
J3U87_RS12375	COG2153	protein acetylation
J3U87_RS12380	COG0585	pseudouridine synthase activity
J3U87_RS12385	COG0739	heme binding
J3U87_RS12385	COG1196	nuclear chromosome segregation
J3U87_RS12385	COG0741	lytic transglycosylase activity
J3U87_RS12390	COG0537	adenosine 5'-monophosphoramidase activity
J3U87_RS12395	COG0515	serine threonine protein kinase
J3U87_RS12395	COG2815	serine threonine protein kinase
J3U87_RS12400	COG1181	Belongs to the D-alanine--D-alanine ligase family
J3U87_RS12405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J3U87_RS12415	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J3U87_RS12420	COG0799	negative regulation of ribosome biogenesis
J3U87_RS12425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J3U87_RS12430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J3U87_RS12435	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J3U87_RS12445	COG1024	Enoyl-CoA hydratase
J3U87_RS12455	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J3U87_RS12525	COG0848	biopolymer transport protein
J3U87_RS12535	COG0811	peptide transport
J3U87_RS12540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J3U87_RS12560	COG2204	response regulator
J3U87_RS12575	COG1366	Belongs to the anti-sigma-factor antagonist family
J3U87_RS12580	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J3U87_RS12585	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J3U87_RS12590	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J3U87_RS12600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J3U87_RS12605	COG0450	alkyl hydroperoxide reductase
J3U87_RS12610	COG4279	zinc finger
J3U87_RS12615	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J3U87_RS12635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J3U87_RS12645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J3U87_RS12650	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J3U87_RS12660	COG0745	RESPONSE REGULATOR receiver
J3U87_RS12665	COG5002	protein histidine kinase activity
J3U87_RS12680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J3U87_RS12700	COG1228	amidohydrolase
J3U87_RS12710	COG0762	integral membrane protein
J3U87_RS12715	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J3U87_RS12730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J3U87_RS12745	COG1115	amino acid carrier protein
J3U87_RS12755	COG0583	DNA-binding transcription factor activity
J3U87_RS12760	COG1555	photosystem II stabilization
J3U87_RS12760	COG1596	polysaccharide export
J3U87_RS12785	COG1131	(ABC) transporter
J3U87_RS12810	COG1596	polysaccharide export
J3U87_RS12840	COG1215	transferase activity, transferring glycosyl groups
J3U87_RS12850	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J3U87_RS12870	COG2815	serine threonine protein kinase
J3U87_RS12870	COG0515	serine threonine protein kinase
J3U87_RS12900	COG5002	protein histidine kinase activity
J3U87_RS12910	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J3U87_RS12915	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J3U87_RS12920	COG1862	Preprotein translocase
J3U87_RS12925	COG0343	queuine tRNA-ribosyltransferase activity
J3U87_RS12935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J3U87_RS12940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J3U87_RS12945	COG1459	type II secretion system
J3U87_RS12985	COG1450	Type ii and iii secretion system protein
J3U87_RS13000	COG0284	orotidine-5'-phosphate decarboxylase activity
J3U87_RS13080	COG0745	RESPONSE REGULATOR receiver
J3U87_RS13085	COG5002	protein histidine kinase activity
J3U87_RS13100	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J3U87_RS13105	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J3U87_RS13115	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J3U87_RS13130	COG0006	proline dipeptidase activity
J3U87_RS13170	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J3U87_RS13175	COG1254	Belongs to the acylphosphatase family
J3U87_RS13180	COG4771	TonB-dependent receptor
J3U87_RS13190	COG0460	homoserine dehydrogenase
J3U87_RS13190	COG0527	aspartate kinase activity
J3U87_RS13195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J3U87_RS13195	COG3453	Protein conserved in bacteria
J3U87_RS13205	COG1331	Highly conserved protein containing a thioredoxin domain
J3U87_RS13210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J3U87_RS13215	COG1132	(ABC) transporter
J3U87_RS13225	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS13225	COG3321	synthase
J3U87_RS13225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS13225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS13225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS13235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS13235	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS13235	COG3321	synthase
J3U87_RS13235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS13235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS13240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS13240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS13240	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS13240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS13240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS13240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS13240	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS13240	COG3321	synthase
J3U87_RS13240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS13240	COG3321	synthase
J3U87_RS13245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS13245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS13245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS13245	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS13245	COG3321	synthase
J3U87_RS13250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS13250	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS13250	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS13250	COG4221	oxidoreductase activity
J3U87_RS13250	COG3321	synthase
J3U87_RS13250	COG4221	oxidoreductase activity
J3U87_RS13250	COG3321	synthase
J3U87_RS13250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS13255	COG3321	synthase
J3U87_RS13255	COG0300	oxidoreductase activity
J3U87_RS13255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS13255	COG4221	oxidoreductase activity
J3U87_RS13270	COG1819	glycosyl
J3U87_RS13280	COG2192	nodulation
J3U87_RS13285	COG0515	serine threonine protein kinase
J3U87_RS13295	COG0438	transferase activity, transferring glycosyl groups
J3U87_RS13295	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J3U87_RS13300	COG0671	phosphoesterase, PA-phosphatase related
J3U87_RS13305	COG4946	Tricorn protease homolog
J3U87_RS13305	COG0793	Belongs to the peptidase S41A family
J3U87_RS13310	COG0577	efflux transmembrane transporter activity
J3U87_RS13315	COG0577	efflux transmembrane transporter activity
J3U87_RS13315	COG1136	(ABC) transporter
J3U87_RS13320	COG4191	Histidine kinase
J3U87_RS13325	COG2204	response regulator
J3U87_RS13340	COG1940	carbohydrate kinase activity
J3U87_RS13345	COG0363	glucosamine-6-phosphate deaminase activity
J3U87_RS13380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J3U87_RS13390	COG0463	Glycosyl transferase, family 2
J3U87_RS13390	COG1216	Glycosyl transferase, family 2
J3U87_RS13395	COG5002	protein histidine kinase activity
J3U87_RS13400	COG0515	serine threonine protein kinase
J3U87_RS13410	COG0179	Fumarylacetoacetate (FAA) hydrolase
J3U87_RS13460	COG1309	transcriptional regulator
J3U87_RS13480	COG2815	serine threonine protein kinase
J3U87_RS13480	COG0515	serine threonine protein kinase
J3U87_RS13490	COG1297	OPT oligopeptide transporter protein
J3U87_RS13510	COG0022	dehydrogenase e1 component
J3U87_RS13515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J3U87_RS13530	COG2226	methyltransferase
J3U87_RS13565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J3U87_RS13570	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J3U87_RS13575	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J3U87_RS13610	COG2192	nodulation
J3U87_RS13660	COG4249	Peptidase C14 caspase catalytic subunit p20
J3U87_RS13660	COG2319	Wd-40 repeat
J3U87_RS13665	COG4771	TonB-dependent receptor
J3U87_RS13685	COG3959	Transketolase, thiamine diphosphate binding domain
J3U87_RS13690	COG3958	Transketolase
J3U87_RS13695	COG1181	Belongs to the D-alanine--D-alanine ligase family
J3U87_RS13725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J3U87_RS13735	COG1648	precorrin-2 dehydrogenase activity
J3U87_RS13735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J3U87_RS13745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J3U87_RS13755	COG0175	sulfate reduction
J3U87_RS13765	COG0175	sulfate reduction
J3U87_RS13770	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J3U87_RS13800	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J3U87_RS13820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J3U87_RS13835	COG0784	Response regulator, receiver
J3U87_RS13835	COG2198	Histidine kinase
J3U87_RS13835	COG2205	protein histidine kinase activity
J3U87_RS13850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J3U87_RS13855	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J3U87_RS13860	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J3U87_RS13865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J3U87_RS13870	COG0195	Participates in both transcription termination and antitermination
J3U87_RS13875	COG0779	Required for maturation of 30S ribosomal subunits
J3U87_RS13900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J3U87_RS13900	COG4191	Histidine kinase
J3U87_RS13905	COG2204	response regulator
J3U87_RS13910	COG0698	ribose 5-phosphate isomerase
J3U87_RS13935	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J3U87_RS13940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J3U87_RS13945	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J3U87_RS13955	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J3U87_RS13960	COG0542	response to heat
J3U87_RS13965	COG1136	(ABC) transporter
J3U87_RS13970	COG4591	ABC-type transport system involved in lipoprotein release permease component
J3U87_RS13985	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J3U87_RS13990	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J3U87_RS14005	COG2022	thiamine diphosphate biosynthetic process
J3U87_RS14010	COG0352	thiamine-phosphate diphosphorylase activity
J3U87_RS14025	COG0745	RESPONSE REGULATOR receiver
J3U87_RS14040	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
J3U87_RS14045	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J3U87_RS14050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J3U87_RS14055	COG0022	dehydrogenase e1 component
J3U87_RS14065	COG0564	pseudouridine synthase activity
J3U87_RS14070	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J3U87_RS14115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J3U87_RS14125	COG0215	cysteine-tRNA ligase activity
J3U87_RS14130	COG2949	membrane
J3U87_RS14160	COG1078	dGTPase activity
J3U87_RS14195	COG0515	serine threonine protein kinase
J3U87_RS14195	COG2815	serine threonine protein kinase
J3U87_RS14215	COG1739	Uncharacterized protein family UPF0029
J3U87_RS14220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J3U87_RS14235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J3U87_RS14250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J3U87_RS14255	COG0515	serine threonine protein kinase
J3U87_RS14255	COG2815	serine threonine protein kinase
J3U87_RS14260	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J3U87_RS14275	COG1127	ABC transporter
J3U87_RS14280	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J3U87_RS14290	COG0358	DNA primase activity
J3U87_RS14305	COG1012	belongs to the aldehyde dehydrogenase family
J3U87_RS14310	COG0667	Aldo Keto reductase
J3U87_RS14315	COG2373	Large extracellular alpha-helical protein
J3U87_RS14345	COG0298	carbon dioxide binding
J3U87_RS14350	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
J3U87_RS14355	COG0375	protein maturation
J3U87_RS14370	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J3U87_RS14375	COG0543	2 iron, 2 sulfur cluster binding
J3U87_RS14390	COG0574	Belongs to the PEP-utilizing enzyme family
J3U87_RS14390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J3U87_RS14395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J3U87_RS14400	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J3U87_RS14405	COG0022	dehydrogenase e1 component
J3U87_RS14405	COG0508	dehydrogenase complex catalyzes the overall conversion of
J3U87_RS14445	COG2089	acid synthase
J3U87_RS14460	COG0154	amidase activity
J3U87_RS14465	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J3U87_RS14485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J3U87_RS14505	COG0071	Belongs to the small heat shock protein (HSP20) family
J3U87_RS14510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J3U87_RS14530	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J3U87_RS14550	COG1858	cytochrome C peroxidase
J3U87_RS14570	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J3U87_RS14580	COG0589	response to stress
J3U87_RS14615	COG3278	Belongs to the heme-copper respiratory oxidase family
J3U87_RS14625	COG0589	response to stress
J3U87_RS14635	COG0745	RESPONSE REGULATOR receiver
J3U87_RS14640	COG2204	response regulator
J3U87_RS14645	COG2204	response regulator
J3U87_RS14650	COG1305	Transglutaminase-like
J3U87_RS14655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J3U87_RS14665	COG0706	membrane insertase activity
J3U87_RS14670	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J3U87_RS14675	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J3U87_RS14680	COG0592	DNA-directed DNA polymerase activity
J3U87_RS14685	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J3U87_RS14690	COG0187	DNA topoisomerase II activity
J3U87_RS14695	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J3U87_RS14700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J3U87_RS14705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J3U87_RS14710	COG0445	tRNA wobble uridine modification
J3U87_RS14715	COG1192	Involved in chromosome partitioning
J3U87_RS14720	COG1475	DNA binding
J3U87_RS14730	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J3U87_RS14735	COG0285	dihydrofolate synthase activity
J3U87_RS14740	COG0745	RESPONSE REGULATOR receiver
J3U87_RS14750	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J3U87_RS14755	COG2884	Cell division ATP-binding protein ftsE
J3U87_RS14760	COG2177	Part of the ABC transporter FtsEX involved in
J3U87_RS14800	COG0714	Associated with various cellular activities
J3U87_RS14810	COG1131	(ABC) transporter
J3U87_RS14885	COG4650	regulator
J3U87_RS14890	COG1690	Belongs to the RtcB family
J3U87_RS14895	COG0430	RNA-3'-phosphate cyclase activity
J3U87_RS14905	COG3034	peptidoglycan biosynthetic process
J3U87_RS14910	COG0113	porphobilinogen synthase activity
J3U87_RS14915	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J3U87_RS14935	COG0271	Belongs to the BolA IbaG family
J3U87_RS14970	COG0515	serine threonine protein kinase
J3U87_RS14970	COG2815	serine threonine protein kinase
J3U87_RS14985	COG1546	Belongs to the CinA family
J3U87_RS14985	COG1058	Belongs to the CinA family
J3U87_RS14995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J3U87_RS15000	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J3U87_RS15005	COG0402	S-adenosylhomocysteine deaminase activity
J3U87_RS15010	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J3U87_RS15015	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J3U87_RS15025	COG1968	undecaprenyl-diphosphatase activity
J3U87_RS15030	COG0418	dihydroorotase activity
J3U87_RS15045	COG0189	ligase activity
J3U87_RS15050	COG2204	response regulator
J3U87_RS15055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J3U87_RS15070	COG3428	Bacterial PH domain
J3U87_RS15080	COG0505	Belongs to the CarA family
J3U87_RS15085	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J3U87_RS15105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J3U87_RS15115	COG0643	Histidine kinase
J3U87_RS15115	COG2198	Histidine kinase
J3U87_RS15120	COG2204	response regulator
J3U87_RS15125	COG4191	Histidine kinase
J3U87_RS15130	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J3U87_RS15140	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J3U87_RS15150	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J3U87_RS15155	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J3U87_RS15160	COG1573	uracil-dna glycosylase
J3U87_RS15165	COG1196	nuclear chromosome segregation
J3U87_RS15175	COG0402	S-adenosylhomocysteine deaminase activity
J3U87_RS15190	COG0367	asparagine synthase
J3U87_RS15195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS15245	COG0513	Belongs to the DEAD box helicase family
J3U87_RS15285	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J3U87_RS15290	COG0159	tryptophan synthase activity
J3U87_RS15295	COG0133	tryptophan synthase activity
J3U87_RS15305	COG0134	indole-3-glycerol-phosphate synthase activity
J3U87_RS15310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J3U87_RS15330	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
J3U87_RS15335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J3U87_RS15340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J3U87_RS15350	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J3U87_RS15355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J3U87_RS15360	COG1086	Polysaccharide biosynthesis protein
J3U87_RS15370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J3U87_RS15380	COG0022	dehydrogenase e1 component
J3U87_RS15390	COG5002	protein histidine kinase activity
J3U87_RS15390	COG2205	protein histidine kinase activity
J3U87_RS15390	COG0784	Response regulator, receiver
J3U87_RS15410	COG1063	alcohol dehydrogenase
J3U87_RS15415	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J3U87_RS15420	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J3U87_RS15430	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J3U87_RS15435	COG1250	3-hydroxyacyl-CoA dehydrogenase
J3U87_RS15455	COG1366	Belongs to the anti-sigma-factor antagonist family
J3U87_RS15470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J3U87_RS15480	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J3U87_RS15495	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J3U87_RS15520	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J3U87_RS15540	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J3U87_RS15545	COG0494	nUDIX hydrolase
J3U87_RS15555	COG0625	glutathione transferase activity
J3U87_RS15595	COG2815	serine threonine protein kinase
J3U87_RS15595	COG0515	serine threonine protein kinase
J3U87_RS15610	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J3U87_RS15610	COG2070	2-Nitropropane dioxygenase
J3U87_RS15615	COG0563	adenylate kinase activity
J3U87_RS15620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J3U87_RS15625	COG2204	response regulator
J3U87_RS15630	COG5000	phosphorelay sensor kinase activity
J3U87_RS15680	COG1199	ATP-dependent helicase activity
J3U87_RS15680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J3U87_RS15685	COG0058	SHG alpha-glucan phosphorylase activity
J3U87_RS15700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J3U87_RS15725	COG2843	Capsule synthesis protein
J3U87_RS15735	COG0668	transmembrane transport
J3U87_RS15795	COG2604	Protein of unknown function DUF115
J3U87_RS15805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J3U87_RS15810	COG0768	penicillin binding
J3U87_RS15820	COG0515	serine threonine protein kinase
J3U87_RS15820	COG2815	serine threonine protein kinase
J3U87_RS15830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J3U87_RS15835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J3U87_RS15840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS15850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J3U87_RS15875	COG1487	ribonuclease activity
J3U87_RS15885	COG2096	Adenosyltransferase
J3U87_RS15900	COG2815	serine threonine protein kinase
J3U87_RS15900	COG0515	serine threonine protein kinase
J3U87_RS15915	COG0625	glutathione transferase activity
J3U87_RS15920	COG3541	Predicted nucleotidyltransferase
J3U87_RS15940	COG4786	Flagellar basal body rod
J3U87_RS15940	COG1256	bacterial-type flagellum assembly
J3U87_RS15965	COG1706	bacterial-type flagellum-dependent cell motility
J3U87_RS15980	COG0826	peptidase U32
J3U87_RS15995	COG1104	cysteine desulfurase activity
J3U87_RS16000	COG0316	Belongs to the HesB IscA family
J3U87_RS16005	COG1215	transferase activity, transferring glycosyl groups
J3U87_RS16035	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J3U87_RS16045	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J3U87_RS16055	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J3U87_RS16080	COG1546	Belongs to the CinA family
J3U87_RS16080	COG1058	Belongs to the CinA family
J3U87_RS16090	COG1301	dicarboxylic acid transport
J3U87_RS16095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J3U87_RS16105	COG0437	4 iron, 4 sulfur cluster binding
J3U87_RS16140	COG2267	carboxylic ester hydrolase activity
J3U87_RS16150	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J3U87_RS16170	COG0745	RESPONSE REGULATOR receiver
J3U87_RS16170	COG3292	Two component regulator propeller
J3U87_RS16170	COG2205	protein histidine kinase activity
J3U87_RS16170	COG0745	RESPONSE REGULATOR receiver
J3U87_RS16170	COG3292	Two component regulator propeller
J3U87_RS16170	COG2205	protein histidine kinase activity
J3U87_RS16180	COG2197	response regulator
J3U87_RS16220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J3U87_RS16225	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J3U87_RS16250	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J3U87_RS16265	COG2205	protein histidine kinase activity
J3U87_RS16310	COG0515	serine threonine protein kinase
J3U87_RS16345	COG1124	(ABC) transporter
J3U87_RS16380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J3U87_RS16385	COG0009	L-threonylcarbamoyladenylate synthase
J3U87_RS16400	COG0745	RESPONSE REGULATOR receiver
J3U87_RS16405	COG2205	protein histidine kinase activity
J3U87_RS16410	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J3U87_RS16430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J3U87_RS16435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS16445	COG1629	transport
J3U87_RS16445	COG4206	TonB-dependent receptor
J3U87_RS16455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J3U87_RS16465	COG0194	GDP metabolic process
J3U87_RS16470	COG1561	YicC-like family, N-terminal region
J3U87_RS16475	COG1132	(ABC) transporter
J3U87_RS16495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J3U87_RS16505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J3U87_RS16510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J3U87_RS16525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J3U87_RS16535	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS16545	COG0424	maF-like protein
J3U87_RS16570	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J3U87_RS16575	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J3U87_RS16580	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J3U87_RS16585	COG1643	Atp-dependent helicase
J3U87_RS16590	COG2226	methyltransferase
J3U87_RS16605	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J3U87_RS16610	COG0181	hydroxymethylbilane synthase activity
J3U87_RS16630	COG1981	membrane
J3U87_RS16635	COG0357	Ribosomal RNA small subunit methyltransferase G
J3U87_RS16640	COG0793	Belongs to the peptidase S41A family
J3U87_RS16675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J3U87_RS16685	COG2205	protein histidine kinase activity
J3U87_RS16690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J3U87_RS16725	COG3852	Histidine kinase
J3U87_RS16730	COG3706	GGDEF domain
J3U87_RS16740	COG0564	pseudouridine synthase activity
J3U87_RS16745	COG2937	Belongs to the GPAT DAPAT family
J3U87_RS16750	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J3U87_RS16750	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J3U87_RS16755	COG0196	riboflavin kinase activity
J3U87_RS16760	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J3U87_RS16775	COG3706	GGDEF domain
J3U87_RS16780	COG0571	ribonuclease III activity
J3U87_RS16785	COG1187	pseudouridine synthase activity
J3U87_RS16790	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J3U87_RS16795	COG0792	nuclease activity
J3U87_RS16800	COG0515	serine threonine protein kinase
J3U87_RS16800	COG2815	serine threonine protein kinase
J3U87_RS16805	COG3204	pilus organization
J3U87_RS16815	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J3U87_RS16840	COG1131	(ABC) transporter
J3U87_RS16850	COG0442	prolyl-tRNA aminoacylation
J3U87_RS16860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J3U87_RS16870	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J3U87_RS16875	COG2226	methyltransferase
J3U87_RS16890	COG0514	ATP-dependent DNA helicase (RecQ)
J3U87_RS16920	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J3U87_RS16920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J3U87_RS16960	COG2165	general secretion pathway protein
J3U87_RS16995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J3U87_RS17000	COG1459	type II secretion system
J3U87_RS17005	COG0438	transferase activity, transferring glycosyl groups
J3U87_RS17085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J3U87_RS17110	COG4974	Belongs to the 'phage' integrase family
J3U87_RS17250	COG2131	deaminase
J3U87_RS17395	COG3586	endonuclease activity
J3U87_RS17415	COG2226	methyltransferase
J3U87_RS17480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS17505	COG0789	Transcriptional regulator
J3U87_RS17510	COG0500	methyltransferase
J3U87_RS17525	COG0644	oxidoreductase
J3U87_RS17560	COG3311	Transcriptional regulator
J3U87_RS17570	COG2319	Wd-40 repeat
J3U87_RS17570	COG4249	Peptidase C14 caspase catalytic subunit p20
J3U87_RS17585	COG4456	Virulence-associated protein
J3U87_RS17600	COG4691	Plasmid stability protein
J3U87_RS17620	COG0861	Integral membrane protein TerC family
J3U87_RS17640	COG2154	pterin-4-alpha-carbinolamine dehydratase
J3U87_RS17650	COG1752	Esterase of the alpha-beta hydrolase superfamily
J3U87_RS17660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J3U87_RS17665	COG4191	Histidine kinase
J3U87_RS17670	COG2204	response regulator
J3U87_RS17695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J3U87_RS17705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J3U87_RS17710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J3U87_RS17715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J3U87_RS17720	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J3U87_RS17730	COG1366	Belongs to the anti-sigma-factor antagonist family
J3U87_RS17735	COG0632	four-way junction helicase activity
J3U87_RS17740	COG2255	four-way junction helicase activity
J3U87_RS17795	COG0018	arginyl-trna synthetase
J3U87_RS17815	COG0463	Glycosyl transferase, family 2
J3U87_RS17840	COG3852	Histidine kinase
J3U87_RS17845	COG2204	response regulator
J3U87_RS17885	COG1435	thymidine kinase activity
J3U87_RS17890	COG0439	Biotin carboxylase
J3U87_RS17895	COG0511	ligase activity, forming carbon-carbon bonds
J3U87_RS17905	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J3U87_RS17920	COG0483	inositol monophosphate 1-phosphatase activity
J3U87_RS17925	COG2003	Belongs to the UPF0758 family
J3U87_RS17950	COG2226	methyltransferase
J3U87_RS17970	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J3U87_RS17975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS17975	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J3U87_RS18000	COG1238	metal cluster binding
J3U87_RS18015	COG1595	DNA-templated transcription, initiation
J3U87_RS18050	COG1960	acyl-CoA dehydrogenase activity
J3U87_RS18055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J3U87_RS18060	COG2205	protein histidine kinase activity
J3U87_RS18065	COG0584	glycerophosphoryl diester phosphodiesterase
J3U87_RS18070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J3U87_RS18075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J3U87_RS18085	COG1752	Esterase of the alpha-beta hydrolase superfamily
J3U87_RS18115	COG0489	protein tyrosine kinase activity
J3U87_RS18120	COG0489	protein tyrosine kinase activity
J3U87_RS18125	COG2201	protein-glutamate methylesterase activity
J3U87_RS18135	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
J3U87_RS18140	COG4206	TonB-dependent receptor
J3U87_RS18145	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J3U87_RS18160	COG1703	isobutyryl-CoA mutase activity
J3U87_RS18160	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J3U87_RS18160	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J3U87_RS18170	COG4771	TonB-dependent receptor
J3U87_RS18220	COG3118	belongs to the thioredoxin family
J3U87_RS18225	COG0564	pseudouridine synthase activity
J3U87_RS18245	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J3U87_RS18250	COG2815	serine threonine protein kinase
J3U87_RS18250	COG0515	serine threonine protein kinase
J3U87_RS18275	COG3485	protocatechuate 3,4-dioxygenase
J3U87_RS18310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J3U87_RS18325	COG1012	belongs to the aldehyde dehydrogenase family
J3U87_RS18330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J3U87_RS18345	COG0745	RESPONSE REGULATOR receiver
J3U87_RS18385	COG1040	competence protein
J3U87_RS18395	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J3U87_RS18400	COG0602	queuosine metabolic process
J3U87_RS18435	COG0149	triose-phosphate isomerase activity
J3U87_RS18450	COG1085	galactose-1-phosphate uridylyltransferase
J3U87_RS18455	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J3U87_RS18460	COG3250	beta-galactosidase activity
J3U87_RS18495	COG0446	pyridine nucleotide-disulphide oxidoreductase
J3U87_RS18495	COG1902	pentaerythritol trinitrate reductase activity
J3U87_RS18500	COG0101	tRNA pseudouridine synthase activity
J3U87_RS18525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J3U87_RS18535	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J3U87_RS18540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J3U87_RS18550	COG0745	RESPONSE REGULATOR receiver
J3U87_RS18560	COG0138	bifunctional purine biosynthesis protein purh
J3U87_RS18565	COG3971	2-oxopent-4-enoate hydratase activity
J3U87_RS18570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J3U87_RS18600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J3U87_RS18650	COG1842	Phage shock protein A
J3U87_RS18655	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J3U87_RS18660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J3U87_RS18670	COG0835	chemotaxis
J3U87_RS18675	COG0643	Histidine kinase
J3U87_RS18675	COG2198	Histidine kinase
J3U87_RS18680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J3U87_RS18690	COG1490	D-aminoacyl-tRNA deacylase activity
J3U87_RS18700	COG2239	Acts as a magnesium transporter
J3U87_RS18720	COG0752	glycyl-tRNA synthetase alpha subunit
J3U87_RS18725	COG0751	glycine-tRNA ligase activity
J3U87_RS18730	COG0574	Belongs to the PEP-utilizing enzyme family
J3U87_RS18730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J3U87_RS18750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J3U87_RS18760	COG0662	Cupin 2, conserved barrel domain protein
J3U87_RS18760	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
J3U87_RS18765	COG1940	carbohydrate kinase activity
J3U87_RS18770	COG3292	Two component regulator propeller
J3U87_RS18770	COG2205	protein histidine kinase activity
J3U87_RS18770	COG0745	RESPONSE REGULATOR receiver
J3U87_RS18790	COG3537	Alpha-1,2-mannosidase
J3U87_RS18805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J3U87_RS18820	COG0515	serine threonine protein kinase
J3U87_RS18820	COG2815	serine threonine protein kinase
J3U87_RS18830	COG0318	PFAM AMP-dependent synthetase and ligase
J3U87_RS18845	COG2204	response regulator
J3U87_RS18850	COG4251	negative regulation of phosphorylation
J3U87_RS18865	COG1950	PFAM Membrane protein of
J3U87_RS18875	COG0489	protein tyrosine kinase activity
J3U87_RS18880	COG0489	protein tyrosine kinase activity
J3U87_RS18885	COG2151	metal-sulfur cluster biosynthetic enzyme
J3U87_RS18890	COG0822	iron-sulfur transferase activity
J3U87_RS18895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J3U87_RS18900	COG0719	Fe-S assembly protein
J3U87_RS18905	COG0396	ATPase activity
J3U87_RS18910	COG0719	Fe-S assembly protein
J3U87_RS18935	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
J3U87_RS18950	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J3U87_RS18965	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J3U87_RS18970	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J3U87_RS19020	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J3U87_RS19030	COG2226	methyltransferase
J3U87_RS19050	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J3U87_RS19055	COG0686	Belongs to the AlaDH PNT family
J3U87_RS19095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J3U87_RS19100	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J3U87_RS19105	COG0066	3-isopropylmalate dehydratase activity
J3U87_RS19110	COG0473	3-isopropylmalate dehydrogenase activity
J3U87_RS19115	COG0823	Involved in the tonB-independent uptake of proteins
J3U87_RS19115	COG1506	peptidase
J3U87_RS19120	COG0776	regulation of translation
J3U87_RS19160	COG0456	acetyltransferase
J3U87_RS19160	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J3U87_RS19165	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J3U87_RS19170	COG4946	Tricorn protease homolog
J3U87_RS19170	COG0793	Belongs to the peptidase S41A family
J3U87_RS19185	COG2814	Major facilitator Superfamily
J3U87_RS19195	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J3U87_RS19245	COG0714	Associated with various cellular activities
J3U87_RS19260	COG1960	acyl-CoA dehydrogenase activity
J3U87_RS19265	COG0237	dephospho-CoA kinase activity
J3U87_RS19290	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J3U87_RS19300	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J3U87_RS19325	COG4191	Histidine kinase
J3U87_RS19330	COG0402	S-adenosylhomocysteine deaminase activity
J3U87_RS19340	COG0010	Belongs to the arginase family
J3U87_RS19345	COG1393	Belongs to the ArsC family
J3U87_RS19360	COG1053	succinate dehydrogenase
J3U87_RS19365	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J3U87_RS19370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J3U87_RS19430	COG3710	Transcriptional regulator
J3U87_RS19445	COG3264	Mechanosensitive ion channel
J3U87_RS19445	COG1196	nuclear chromosome segregation
J3U87_RS19465	COG0768	penicillin binding
J3U87_RS19470	COG0772	Belongs to the SEDS family
J3U87_RS19490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J3U87_RS19495	COG0017	Asparaginyl-tRNA synthetase
J3U87_RS19510	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J3U87_RS19535	COG4181	ATPase activity
J3U87_RS19540	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J3U87_RS19555	COG0400	carboxylic ester hydrolase activity
J3U87_RS19565	COG0784	Response regulator, receiver
J3U87_RS19570	COG2202	Pas domain
J3U87_RS19570	COG2205	protein histidine kinase activity
J3U87_RS19575	COG1842	Phage shock protein A
J3U87_RS19585	COG0484	heat shock protein binding
J3U87_RS19590	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J3U87_RS19610	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
J3U87_RS19650	COG3483	tryptophan 2,3-dioxygenase activity
J3U87_RS19665	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J3U87_RS19670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J3U87_RS19685	COG2198	Histidine kinase
J3U87_RS19685	COG0643	Histidine kinase
J3U87_RS19685	COG0784	Response regulator, receiver
J3U87_RS19690	COG0835	chemotaxis
J3U87_RS19695	COG2201	protein-glutamate methylesterase activity
J3U87_RS19705	COG5002	protein histidine kinase activity
J3U87_RS19720	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J3U87_RS19740	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
J3U87_RS19750	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J3U87_RS19755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J3U87_RS19760	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J3U87_RS19765	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J3U87_RS19770	COG0072	phenylalanine-tRNA ligase activity
J3U87_RS19770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J3U87_RS19790	COG1692	metallophosphoesterase
J3U87_RS19795	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J3U87_RS19800	COG4399	Belongs to the UPF0754 family
J3U87_RS19830	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J3U87_RS19835	COG0049	tRNA binding
J3U87_RS19840	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J3U87_RS19845	COG0051	transcription antitermination factor activity, RNA binding
J3U87_RS19850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J3U87_RS19855	COG0088	Forms part of the polypeptide exit tunnel
J3U87_RS19860	COG0089	rRNA binding
J3U87_RS19865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J3U87_RS19870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J3U87_RS19875	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J3U87_RS19880	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J3U87_RS19885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J3U87_RS19890	COG0255	Belongs to the universal ribosomal protein uL29 family
J3U87_RS19895	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J3U87_RS19900	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J3U87_RS19905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J3U87_RS19910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J3U87_RS19915	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J3U87_RS19920	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J3U87_RS19925	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J3U87_RS19930	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J3U87_RS19950	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J3U87_RS19960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J3U87_RS19965	COG0202	RNA polymerase activity
J3U87_RS19970	COG0203	ribosomal protein L17
J3U87_RS19975	COG0519	Catalyzes the synthesis of GMP from XMP
J3U87_RS19975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J3U87_RS19980	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
J3U87_RS19995	COG1960	acyl-CoA dehydrogenase activity
J3U87_RS20015	COG0252	asparaginase activity
J3U87_RS20050	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J3U87_RS20060	COG4607	ABC-type enterochelin transport system periplasmic component
J3U87_RS20065	COG1120	ATPase activity
J3U87_RS20100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J3U87_RS20110	COG0151	Belongs to the GarS family
J3U87_RS20145	COG2205	protein histidine kinase activity
J3U87_RS20145	COG0784	Response regulator, receiver
J3U87_RS20150	COG0135	phosphoribosylanthranilate isomerase activity
J3U87_RS20180	COG0415	Belongs to the DNA photolyase family
J3U87_RS20190	COG0789	Transcriptional regulator
J3U87_RS20205	COG0077	Prephenate dehydratase
J3U87_RS20205	COG1605	Chorismate mutase
J3U87_RS20210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J3U87_RS20215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J3U87_RS20215	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J3U87_RS20220	COG0314	molybdopterin synthase activity
J3U87_RS20230	COG1288	antiporter activity
J3U87_RS20245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J3U87_RS20270	COG0628	permease
J3U87_RS20280	COG0612	Peptidase, M16
J3U87_RS20285	COG0756	dUTP diphosphatase activity
J3U87_RS20295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J3U87_RS20305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J3U87_RS20310	COG0776	regulation of translation
J3U87_RS20315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J3U87_RS20325	COG2204	response regulator
J3U87_RS20350	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J3U87_RS20350	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J3U87_RS20355	COG3118	belongs to the thioredoxin family
J3U87_RS20360	COG0084	hydrolase, TatD family'
J3U87_RS20365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J3U87_RS20400	COG0492	ferredoxin-NADP+ reductase activity
J3U87_RS20405	COG1678	Uncharacterized ACR, COG1678
J3U87_RS20425	COG4191	Histidine kinase
J3U87_RS20440	COG0745	RESPONSE REGULATOR receiver
J3U87_RS20445	COG2205	protein histidine kinase activity
J3U87_RS20450	COG1538	Outer membrane efflux protein
J3U87_RS20455	COG1566	PFAM secretion protein HlyD family protein
J3U87_RS20465	COG0702	epimerase
J3U87_RS20480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J3U87_RS20495	COG1131	(ABC) transporter
J3U87_RS20505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J3U87_RS20540	COG3321	synthase
J3U87_RS20540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS20570	COG0589	response to stress
J3U87_RS20605	COG0009	L-threonylcarbamoyladenylate synthase
J3U87_RS20610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J3U87_RS20680	COG0788	formyltetrahydrofolate deformylase activity
J3U87_RS20685	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J3U87_RS20695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J3U87_RS20725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS20725	COG3321	synthase
J3U87_RS20725	COG0300	oxidoreductase activity
J3U87_RS20725	COG0318	PFAM AMP-dependent synthetase and ligase
J3U87_RS20725	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS20735	COG0277	FAD linked oxidase domain protein
J3U87_RS20735	COG0247	lactate metabolic process
J3U87_RS20745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J3U87_RS20750	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J3U87_RS20770	COG1696	Membrane protein involved in D-alanine export
J3U87_RS20780	COG1132	(ABC) transporter
J3U87_RS20785	COG1132	(ABC) transporter
J3U87_RS20805	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J3U87_RS20810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J3U87_RS20825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J3U87_RS20830	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J3U87_RS20835	COG0772	Belongs to the SEDS family
J3U87_RS20840	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J3U87_RS20845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J3U87_RS20850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J3U87_RS20870	COG0275	rRNA processing
J3U87_RS20875	COG2001	Belongs to the MraZ family
J3U87_RS20880	COG2235	arginine
J3U87_RS20930	COG4753	response regulator
J3U87_RS20930	COG2207	Transcriptional regulator
J3U87_RS20935	COG2340	Cysteine-rich secretory protein family
J3U87_RS20940	COG0673	inositol 2-dehydrogenase activity
J3U87_RS20970	COG1612	heme a metabolic process
J3U87_RS20990	COG0556	nucleotide-excision repair
J3U87_RS21000	COG1166	arginine decarboxylase activity
J3U87_RS21010	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J3U87_RS21015	COG5002	protein histidine kinase activity
J3U87_RS21015	COG0784	Response regulator, receiver
J3U87_RS21015	COG2205	protein histidine kinase activity
J3U87_RS21030	COG2226	methyltransferase
J3U87_RS21055	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J3U87_RS21075	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J3U87_RS21100	COG0301	tRNA thio-modification
J3U87_RS21110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J3U87_RS21115	COG0569	domain protein
J3U87_RS21120	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
J3U87_RS21125	COG0156	8-amino-7-oxononanoate synthase activity
J3U87_RS21150	COG0840	transmembrane signaling receptor activity
J3U87_RS21160	COG3104	oligopeptide transport
J3U87_RS21165	COG2814	Major facilitator Superfamily
J3U87_RS21180	COG0167	dihydroorotate dehydrogenase activity
J3U87_RS21185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J3U87_RS21215	COG0521	Mo-molybdopterin cofactor biosynthetic process
J3U87_RS21220	COG2249	NAD(P)H dehydrogenase (quinone) activity
J3U87_RS21225	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J3U87_RS21260	COG1530	ribonuclease E activity
J3U87_RS21270	COG0471	metal ion transport
J3U87_RS21270	COG3273	potassium ion transport
J3U87_RS21300	COG0500	methyltransferase
J3U87_RS21310	COG4106	trans-aconitate 2-methyltransferase activity
J3U87_RS21360	COG1115	amino acid carrier protein
J3U87_RS21365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J3U87_RS21375	COG0484	heat shock protein binding
J3U87_RS21380	COG0443	Heat shock 70 kDa protein
J3U87_RS21390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J3U87_RS21395	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J3U87_RS21400	COG1917	Cupin 2, conserved barrel domain protein
J3U87_RS21400	COG4977	sequence-specific DNA binding
J3U87_RS21410	COG1794	racemase activity, acting on amino acids and derivatives
J3U87_RS21430	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J3U87_RS21430	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J3U87_RS21455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J3U87_RS21470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J3U87_RS21475	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
J3U87_RS21495	COG2815	serine threonine protein kinase
J3U87_RS21495	COG0515	serine threonine protein kinase
J3U87_RS21510	COG1404	Belongs to the peptidase S8 family
J3U87_RS21525	COG2873	o-acetylhomoserine
J3U87_RS21535	COG2815	serine threonine protein kinase
J3U87_RS21535	COG0515	serine threonine protein kinase
J3U87_RS21540	COG0784	Response regulator, receiver
J3U87_RS21540	COG2205	protein histidine kinase activity
J3U87_RS21545	COG1215	transferase activity, transferring glycosyl groups
J3U87_RS21560	COG0583	DNA-binding transcription factor activity
J3U87_RS21565	COG0443	Heat shock 70 kDa protein
J3U87_RS21590	COG3956	TIGRFAM MazG family protein
J3U87_RS21605	COG2205	protein histidine kinase activity
J3U87_RS21605	COG0784	Response regulator, receiver
J3U87_RS21605	COG2198	Histidine kinase
J3U87_RS21620	COG0484	heat shock protein binding
J3U87_RS21630	COG0443	Heat shock 70 kDa protein
J3U87_RS21680	COG0024	Methionine aminopeptidase
J3U87_RS21735	COG1595	DNA-templated transcription, initiation
J3U87_RS21750	COG0646	methionine synthase
J3U87_RS21750	COG1410	methionine synthase
J3U87_RS21755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J3U87_RS21780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J3U87_RS21800	COG1705	Flagellar rod assembly protein muramidase FlgJ
J3U87_RS21800	COG1388	LysM domain
J3U87_RS21810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J3U87_RS21820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J3U87_RS21830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J3U87_RS21830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J3U87_RS21845	COG2861	carbohydrate metabolic process
J3U87_RS21850	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J3U87_RS21860	COG0494	nUDIX hydrolase
J3U87_RS21870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J3U87_RS21885	COG0515	serine threonine protein kinase
J3U87_RS21885	COG2815	serine threonine protein kinase
J3U87_RS21895	COG1619	proteins homologs of microcin C7 resistance protein MccF
J3U87_RS21905	COG0515	serine threonine protein kinase
J3U87_RS21905	COG2815	serine threonine protein kinase
J3U87_RS21940	COG2433	Pfam Transposase IS66
J3U87_RS21955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J3U87_RS21960	COG1331	Highly conserved protein containing a thioredoxin domain
J3U87_RS21975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS21975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS21975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS21975	COG3321	synthase
J3U87_RS21975	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS21990	COG2205	protein histidine kinase activity
J3U87_RS21990	COG3292	Two component regulator propeller
J3U87_RS21990	COG0745	RESPONSE REGULATOR receiver
J3U87_RS22040	COG3436	PFAM IS66 Orf2 family protein
J3U87_RS22130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J3U87_RS22140	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J3U87_RS22145	COG0515	serine threonine protein kinase
J3U87_RS22145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J3U87_RS22220	COG3047	cAMP biosynthetic process
J3U87_RS22225	COG2198	Histidine kinase
J3U87_RS22225	COG0784	Response regulator, receiver
J3U87_RS22225	COG2205	protein histidine kinase activity
J3U87_RS22235	COG1136	(ABC) transporter
J3U87_RS22235	COG0577	efflux transmembrane transporter activity
J3U87_RS22240	COG1136	(ABC) transporter
J3U87_RS22240	COG0577	efflux transmembrane transporter activity
J3U87_RS22245	COG1136	(ABC) transporter
J3U87_RS22310	COG1136	(ABC) transporter
J3U87_RS22315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3U87_RS22325	COG0538	isocitrate dehydrogenase activity
J3U87_RS22340	COG5002	protein histidine kinase activity
J3U87_RS22340	COG2205	protein histidine kinase activity
J3U87_RS22340	COG0784	Response regulator, receiver
J3U87_RS22385	COG3275	phosphorelay sensor kinase activity
J3U87_RS22400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS22460	COG3344	reverse transcriptase
J3U87_RS22570	COG3227	Zinc metalloprotease (Elastase)
J3U87_RS22590	COG1045	serine acetyltransferase
J3U87_RS22610	COG0318	PFAM AMP-dependent synthetase and ligase
J3U87_RS22640	COG2818	Glycosylase
J3U87_RS22665	COG1595	DNA-templated transcription, initiation
J3U87_RS22675	COG1505	serine-type exopeptidase activity
J3U87_RS22735	COG0745	RESPONSE REGULATOR receiver
J3U87_RS22740	COG4251	negative regulation of phosphorylation
J3U87_RS22785	COG0367	asparagine synthase
J3U87_RS22800	COG0784	Response regulator, receiver
J3U87_RS22800	COG2198	Histidine kinase
J3U87_RS22800	COG5002	protein histidine kinase activity
J3U87_RS22810	COG1858	cytochrome C peroxidase
J3U87_RS22825	COG0840	transmembrane signaling receptor activity
J3U87_RS22830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3U87_RS22840	COG1538	Outer membrane efflux protein
J3U87_RS22845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J3U87_RS22890	COG1846	Transcriptional regulator
J3U87_RS22895	COG1764	response to oxidative stress
J3U87_RS22905	COG0840	transmembrane signaling receptor activity
J3U87_RS22985	COG4932	domain protein
J3U87_RS22990	COG3005	denitrification pathway
J3U87_RS22995	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J3U87_RS23015	COG3275	phosphorelay sensor kinase activity
J3U87_RS23025	COG4774	siderophore transport
J3U87_RS23045	COG3710	Transcriptional regulator
J3U87_RS23050	COG1228	amidohydrolase
J3U87_RS23060	COG4206	TonB-dependent receptor
J3U87_RS23095	COG0300	oxidoreductase activity
J3U87_RS23110	COG2356	endonuclease I
J3U87_RS23130	COG2151	metal-sulfur cluster biosynthetic enzyme
J3U87_RS23130	COG0489	protein tyrosine kinase activity
J3U87_RS23170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J3U87_RS23175	COG1845	cytochrome c oxidase, subunit III
J3U87_RS23195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J3U87_RS23200	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
J3U87_RS23205	COG0535	radical SAM domain protein
J3U87_RS23235	COG1309	transcriptional regulator
J3U87_RS23260	COG1522	sequence-specific DNA binding
J3U87_RS23270	COG0424	maF-like protein
J3U87_RS23275	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J3U87_RS23280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J3U87_RS23290	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J3U87_RS23295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J3U87_RS23320	COG3710	Transcriptional regulator
J3U87_RS23325	COG1404	Belongs to the peptidase S8 family
J3U87_RS23345	COG0688	phosphatidylethanolamine metabolic process
J3U87_RS23405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J3U87_RS23410	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J3U87_RS23425	COG0745	RESPONSE REGULATOR receiver
J3U87_RS23485	COG2433	Pfam Transposase IS66
J3U87_RS23545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J3U87_RS23560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J3U87_RS23880	COG0529	Catalyzes the synthesis of activated sulfate
J3U87_RS23885	COG0277	FAD linked oxidase domain protein
J3U87_RS23890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J3U87_RS23895	COG0784	Response regulator, receiver
J3U87_RS23895	COG2205	protein histidine kinase activity
J3U87_RS23900	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS23915	COG3256	nitric oxide reductase
J3U87_RS23940	COG0037	tRNA processing
J3U87_RS23945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J3U87_RS23985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J3U87_RS24005	COG3279	Response regulator of the LytR AlgR family
J3U87_RS24035	COG4941	Belongs to the sigma-70 factor family
J3U87_RS24040	COG3795	YCII-related domain
J3U87_RS24050	COG2358	TRAP transporter, solute receptor (TAXI family
J3U87_RS24055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J3U87_RS24090	COG0515	serine threonine protein kinase
J3U87_RS24095	COG2204	response regulator
J3U87_RS24105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J3U87_RS24120	COG3387	PFAM Glycoside hydrolase 15-related
J3U87_RS24125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J3U87_RS24150	COG0151	Belongs to the GarS family
J3U87_RS24155	COG0183	Belongs to the thiolase family
J3U87_RS24160	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J3U87_RS24170	COG3885	ferrous iron binding
J3U87_RS24170	COG2078	PFAM AMMECR1 domain protein
J3U87_RS24215	COG4585	Histidine kinase
J3U87_RS24225	COG2197	response regulator
J3U87_RS24235	COG0659	secondary active sulfate transmembrane transporter activity
J3U87_RS24305	COG2815	serine threonine protein kinase
J3U87_RS24305	COG0515	serine threonine protein kinase
J3U87_RS24310	COG5002	protein histidine kinase activity
J3U87_RS24315	COG0745	RESPONSE REGULATOR receiver
J3U87_RS24335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J3U87_RS24355	COG1022	Amp-dependent synthetase and ligase
J3U87_RS24360	COG0534	Mate efflux family protein
J3U87_RS24385	COG0124	histidyl-tRNA synthetase
J3U87_RS24390	COG1136	(ABC) transporter
J3U87_RS24405	COG3012	SEC-C Motif Domain Protein
J3U87_RS24435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J3U87_RS24440	COG0076	glutamate decarboxylase activity
J3U87_RS24465	COG3597	protein domain associated with
J3U87_RS24475	COG3437	response regulator, receiver
J3U87_RS24485	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J3U87_RS24490	COG2201	protein-glutamate methylesterase activity
J3U87_RS24495	COG0835	chemotaxis
J3U87_RS24505	COG0784	Response regulator, receiver
J3U87_RS24505	COG0643	Histidine kinase
J3U87_RS24505	COG2198	Histidine kinase
J3U87_RS24560	COG5002	protein histidine kinase activity
J3U87_RS24565	COG0745	RESPONSE REGULATOR receiver
J3U87_RS24570	COG2207	Transcriptional regulator
J3U87_RS24645	COG2311	Membrane
J3U87_RS24650	COG1725	Transcriptional regulator
J3U87_RS24655	COG1131	(ABC) transporter
J3U87_RS24670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS24710	COG0318	PFAM AMP-dependent synthetase and ligase
J3U87_RS24720	COG4615	Cyclic peptide transporter
J3U87_RS24735	COG4191	Histidine kinase
J3U87_RS24765	COG0745	RESPONSE REGULATOR receiver
J3U87_RS24775	COG4249	Peptidase C14 caspase catalytic subunit p20
J3U87_RS24775	COG2319	Wd-40 repeat
J3U87_RS24785	COG1858	cytochrome C peroxidase
J3U87_RS24795	COG0626	cystathionine gamma-synthase activity
J3U87_RS24820	COG2207	Transcriptional regulator
J3U87_RS24830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J3U87_RS24845	COG1335	isochorismatase
J3U87_RS24850	COG0583	DNA-binding transcription factor activity
J3U87_RS24885	COG2205	protein histidine kinase activity
J3U87_RS24890	COG0745	RESPONSE REGULATOR receiver
J3U87_RS24910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J3U87_RS24925	COG3425	synthase
J3U87_RS24930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS24935	COG0515	serine threonine protein kinase
J3U87_RS24935	COG2815	serine threonine protein kinase
J3U87_RS24980	COG3227	Zinc metalloprotease (Elastase)
J3U87_RS24980	COG3227	Zinc metalloprotease (Elastase)
J3U87_RS24985	COG3279	Response regulator of the LytR AlgR family
J3U87_RS24990	COG3275	phosphorelay sensor kinase activity
J3U87_RS25010	COG0405	Gamma-glutamyltransferase
J3U87_RS25030	COG2205	protein histidine kinase activity
J3U87_RS25030	COG0745	RESPONSE REGULATOR receiver
J3U87_RS25030	COG3292	Two component regulator propeller
J3U87_RS25040	COG0515	serine threonine protein kinase
J3U87_RS25040	COG2815	serine threonine protein kinase
J3U87_RS25080	COG1595	DNA-templated transcription, initiation
J3U87_RS25085	COG0346	lactoylglutathione lyase activity
J3U87_RS25115	COG2815	serine threonine protein kinase
J3U87_RS25115	COG0515	serine threonine protein kinase
J3U87_RS25150	COG0784	Response regulator, receiver
J3U87_RS25150	COG5002	protein histidine kinase activity
J3U87_RS25150	COG2198	Histidine kinase
J3U87_RS25155	COG0515	serine threonine protein kinase
J3U87_RS25155	COG2815	serine threonine protein kinase
J3U87_RS25160	COG2815	serine threonine protein kinase
J3U87_RS25160	COG0515	serine threonine protein kinase
J3U87_RS25175	COG3209	COG3209 Rhs family protein
J3U87_RS25185	COG3344	reverse transcriptase
J3U87_RS25200	COG0583	DNA-binding transcription factor activity
J3U87_RS25250	COG4615	Cyclic peptide transporter
J3U87_RS25270	COG3185	4-Hydroxyphenylpyruvate dioxygenase
J3U87_RS25295	COG1629	transport
J3U87_RS25295	COG4774	siderophore transport
J3U87_RS25385	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J3U87_RS25405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J3U87_RS25410	COG0435	Glutathione S-transferase
J3U87_RS25425	COG3361	conserved protein (COG2071)
J3U87_RS25435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J3U87_RS25455	COG5000	phosphorelay sensor kinase activity
J3U87_RS25470	COG0840	transmembrane signaling receptor activity
J3U87_RS25480	COG1192	Involved in chromosome partitioning
J3U87_RS25500	COG2815	serine threonine protein kinase
J3U87_RS25500	COG0515	serine threonine protein kinase
J3U87_RS25525	COG4771	TonB-dependent receptor
J3U87_RS25560	COG2084	Dehydrogenase
J3U87_RS25565	COG0583	DNA-binding transcription factor activity
J3U87_RS25595	COG0515	serine threonine protein kinase
J3U87_RS25625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J3U87_RS25650	COG1595	DNA-templated transcription, initiation
J3U87_RS25660	COG3708	Transcriptional regulator
J3U87_RS25660	COG2207	Transcriptional regulator
J3U87_RS25735	COG2207	Transcriptional regulator
J3U87_RS25745	COG4771	TonB-dependent receptor
J3U87_RS25820	COG1858	cytochrome C peroxidase
J3U87_RS25870	COG0300	oxidoreductase activity
J3U87_RS25885	COG0251	oxidation-reduction process
J3U87_RS25900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J3U87_RS25925	COG0515	serine threonine protein kinase
J3U87_RS25925	COG2815	serine threonine protein kinase
J3U87_RS25935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J3U87_RS25940	COG5297	Belongs to the glycosyl hydrolase family 6
J3U87_RS25940	COG4733	cellulase activity
J3U87_RS25955	COG2226	methyltransferase
J3U87_RS25960	COG1280	lysine exporter protein (LysE YggA)
J3U87_RS26010	COG1335	isochorismatase
J3U87_RS26015	COG1741	Belongs to the pirin family
J3U87_RS26030	COG2113	Glycine betaine
J3U87_RS26035	COG5002	protein histidine kinase activity
J3U87_RS26055	COG3706	GGDEF domain
J3U87_RS26070	COG2205	protein histidine kinase activity
J3U87_RS26070	COG0784	Response regulator, receiver
J3U87_RS26085	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J3U87_RS26090	COG1283	sodium-dependent phosphate transmembrane transporter activity
J3U87_RS26100	COG1295	ribonuclease BN
J3U87_RS26115	COG2304	oxidoreductase activity
J3U87_RS26180	COG0745	RESPONSE REGULATOR receiver
J3U87_RS26185	COG4191	Histidine kinase
J3U87_RS26190	COG2267	carboxylic ester hydrolase activity
J3U87_RS26210	COG1136	(ABC) transporter
J3U87_RS26210	COG0577	efflux transmembrane transporter activity
J3U87_RS26215	COG1136	(ABC) transporter
J3U87_RS26215	COG0577	efflux transmembrane transporter activity
J3U87_RS26225	COG4191	Histidine kinase
J3U87_RS26235	COG0583	DNA-binding transcription factor activity
J3U87_RS26240	COG1024	Enoyl-CoA hydratase
J3U87_RS26250	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS26255	COG0745	RESPONSE REGULATOR receiver
J3U87_RS26255	COG2205	protein histidine kinase activity
J3U87_RS26255	COG3292	Two component regulator propeller
J3U87_RS26265	COG4251	negative regulation of phosphorylation
J3U87_RS26275	COG0484	heat shock protein binding
J3U87_RS26285	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J3U87_RS26285	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J3U87_RS26290	COG0805	protein transport
J3U87_RS26320	COG2207	Transcriptional regulator
J3U87_RS26335	COG3292	Two component regulator propeller
J3U87_RS26335	COG2205	protein histidine kinase activity
J3U87_RS26335	COG0745	RESPONSE REGULATOR receiver
J3U87_RS26355	COG0515	serine threonine protein kinase
J3U87_RS26355	COG2815	serine threonine protein kinase
J3U87_RS26360	COG1234	tRNA 3'-trailer cleavage
J3U87_RS26370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J3U87_RS26380	COG0668	transmembrane transport
J3U87_RS26400	COG0848	biopolymer transport protein
J3U87_RS26430	COG0596	Alpha beta hydrolase
J3U87_RS26440	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
J3U87_RS26470	COG0500	methyltransferase
J3U87_RS26490	COG3119	arylsulfatase activity
J3U87_RS26500	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J3U87_RS26505	COG1720	tRNA m6t6A37 methyltransferase activity
J3U87_RS26540	COG2204	response regulator
J3U87_RS26565	COG2133	pyrroloquinoline quinone binding
J3U87_RS26570	COG1921	L-seryl-tRNASec selenium transferase activity
J3U87_RS26585	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J3U87_RS26605	COG2205	protein histidine kinase activity
J3U87_RS26615	COG2204	response regulator
J3U87_RS26665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J3U87_RS26665	COG2070	2-Nitropropane dioxygenase
J3U87_RS26685	COG2815	serine threonine protein kinase
J3U87_RS26685	COG0515	serine threonine protein kinase
J3U87_RS26700	COG4912	Dna alkylation repair
J3U87_RS26715	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J3U87_RS26720	COG4326	sporulation control protein
J3U87_RS26725	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J3U87_RS26750	COG0791	NLP P60 protein
J3U87_RS26750	COG1388	LysM domain
J3U87_RS26780	COG2205	protein histidine kinase activity
J3U87_RS26785	COG0745	RESPONSE REGULATOR receiver
J3U87_RS26820	COG0515	serine threonine protein kinase
J3U87_RS26820	COG2815	serine threonine protein kinase
J3U87_RS26850	COG2205	protein histidine kinase activity
J3U87_RS26850	COG0784	Response regulator, receiver
J3U87_RS26860	COG1404	Belongs to the peptidase S8 family
J3U87_RS26880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J3U87_RS26890	COG0793	Belongs to the peptidase S41A family
J3U87_RS26900	COG1309	transcriptional regulator
J3U87_RS26905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J3U87_RS26915	COG4999	Histidine kinase
J3U87_RS26915	COG3850	Histidine kinase
J3U87_RS26915	COG3437	response regulator, receiver
J3U87_RS26915	COG2205	protein histidine kinase activity
J3U87_RS26920	COG2205	protein histidine kinase activity
J3U87_RS26920	COG5002	protein histidine kinase activity
J3U87_RS26920	COG0784	Response regulator, receiver
J3U87_RS26935	COG0300	oxidoreductase activity
J3U87_RS26955	COG3321	synthase
J3U87_RS26960	COG1506	peptidase
J3U87_RS26960	COG0823	Involved in the tonB-independent uptake of proteins
J3U87_RS26965	COG0339	signal peptide processing
J3U87_RS26975	COG1475	DNA binding
J3U87_RS26980	COG1192	Involved in chromosome partitioning
J3U87_RS26985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J3U87_RS27000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J3U87_RS27015	COG1473	amidohydrolase
J3U87_RS27025	COG4615	Cyclic peptide transporter
J3U87_RS27050	COG1070	Carbohydrate kinase
J3U87_RS27055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J3U87_RS27060	COG0277	FAD linked oxidase domain protein
J3U87_RS27065	COG2186	Transcriptional regulator
J3U87_RS27070	COG5002	protein histidine kinase activity
J3U87_RS27070	COG0784	Response regulator, receiver
J3U87_RS27070	COG2205	protein histidine kinase activity
J3U87_RS27085	COG5001	Diguanylate cyclase
J3U87_RS27085	COG4251	negative regulation of phosphorylation
J3U87_RS27085	COG3706	GGDEF domain
J3U87_RS27085	COG2203	Gaf domain
J3U87_RS27115	COG2205	protein histidine kinase activity
J3U87_RS27145	COG1404	Belongs to the peptidase S8 family
J3U87_RS27150	COG0463	Glycosyl transferase, family 2
J3U87_RS27160	COG1942	4-Oxalocrotonate Tautomerase
J3U87_RS27165	COG1253	flavin adenine dinucleotide binding
J3U87_RS27170	COG3033	Beta-eliminating lyase
J3U87_RS27195	COG0517	IMP dehydrogenase activity
J3U87_RS27205	COG0517	IMP dehydrogenase activity
J3U87_RS27215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J3U87_RS27220	COG1518	maintenance of DNA repeat elements
J3U87_RS27250	COG1203	CRISPR-associated helicase, Cas3
J3U87_RS27315	COG0644	oxidoreductase
J3U87_RS27320	COG0517	IMP dehydrogenase activity
J3U87_RS27345	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J3U87_RS27355	COG0517	IMP dehydrogenase activity
J3U87_RS27405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J3U87_RS27410	COG3290	protein histidine kinase activity
J3U87_RS27440	COG2234	aminopeptidase activity
J3U87_RS27480	COG0463	Glycosyl transferase, family 2
J3U87_RS27575	COG1574	metal-dependent hydrolase with the TIM-barrel fold
J3U87_RS27585	COG0840	transmembrane signaling receptor activity
J3U87_RS27595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J3U87_RS27600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J3U87_RS27600	COG4651	solute:proton antiporter activity
J3U87_RS27620	COG2234	aminopeptidase activity
J3U87_RS27630	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
J3U87_RS27650	COG1269	ATP hydrolysis coupled proton transport
J3U87_RS27655	COG1394	ATPase activity, coupled to movement of substances
J3U87_RS27670	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J3U87_RS27675	COG1056	cytidyltransferase-related domain
J3U87_RS27675	COG1051	belongs to the nudix hydrolase family
J3U87_RS27725	COG1595	DNA-templated transcription, initiation
J3U87_RS27730	COG0438	transferase activity, transferring glycosyl groups
J3U87_RS27745	COG3279	Response regulator of the LytR AlgR family
J3U87_RS27810	COG0793	Belongs to the peptidase S41A family
J3U87_RS27865	COG0326	Molecular chaperone. Has ATPase activity
J3U87_RS28000	COG3609	addiction module antidote protein, CC2985 family
J3U87_RS28040	COG0626	cystathionine gamma-synthase activity
J3U87_RS28045	COG0626	cystathionine gamma-synthase activity
J3U87_RS28095	COG2205	protein histidine kinase activity
J3U87_RS28095	COG0784	Response regulator, receiver
J3U87_RS28100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J3U87_RS28105	COG4251	negative regulation of phosphorylation
J3U87_RS28125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J3U87_RS28130	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J3U87_RS28140	COG1454	alcohol dehydrogenase
J3U87_RS28155	COG2089	acid synthase
J3U87_RS28165	COG3209	COG3209 Rhs family protein
J3U87_RS28190	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J3U87_RS28195	COG0302	gtp cyclohydrolase
J3U87_RS28235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J3U87_RS28245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J3U87_RS28255	COG0346	lactoylglutathione lyase activity
J3U87_RS28275	COG3710	Transcriptional regulator
J3U87_RS28285	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J3U87_RS28320	COG2204	response regulator
J3U87_RS28345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J3U87_RS28375	COG2217	Heavy metal translocating P-type atpase
J3U87_RS28435	COG3279	Response regulator of the LytR AlgR family
J3U87_RS28440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J3U87_RS28470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS28475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS28485	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J3U87_RS28500	COG2815	serine threonine protein kinase
J3U87_RS28500	COG0515	serine threonine protein kinase
J3U87_RS28545	COG2111	Na H antiporter
J3U87_RS28545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J3U87_RS28555	COG0651	ATP synthesis coupled electron transport
J3U87_RS28560	COG0651	ATP synthesis coupled electron transport
J3U87_RS28625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J3U87_RS28635	COG0494	nUDIX hydrolase
J3U87_RS28645	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
J3U87_RS28670	COG2203	Gaf domain
J3U87_RS28670	COG2199	diguanylate cyclase activity
J3U87_RS28685	COG4249	Peptidase C14 caspase catalytic subunit p20
J3U87_RS28685	COG2319	Wd-40 repeat
J3U87_RS28715	COG5002	protein histidine kinase activity
J3U87_RS28735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3U87_RS28750	COG0789	Transcriptional regulator
J3U87_RS28765	COG0641	radical SAM
J3U87_RS28860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J3U87_RS28970	COG0582	viral genome integration into host DNA
J3U87_RS29175	COG0631	protein serine/threonine phosphatase activity
J3U87_RS29220	COG3275	phosphorelay sensor kinase activity
J3U87_RS29225	COG3279	Response regulator of the LytR AlgR family
J3U87_RS29250	COG0189	ligase activity
J3U87_RS29250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J3U87_RS29255	COG0367	asparagine synthase
J3U87_RS29270	COG3485	protocatechuate 3,4-dioxygenase
J3U87_RS29285	COG2204	response regulator
J3U87_RS29290	COG2814	Major facilitator Superfamily
J3U87_RS29320	COG3275	phosphorelay sensor kinase activity
J3U87_RS29325	COG3279	Response regulator of the LytR AlgR family
J3U87_RS29330	COG3507	Belongs to the glycosyl hydrolase 43 family
J3U87_RS29345	COG1070	Carbohydrate kinase
J3U87_RS29355	COG2814	Major facilitator Superfamily
J3U87_RS29370	COG4771	TonB-dependent receptor
J3U87_RS29385	COG0154	amidase activity
J3U87_RS29410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J3U87_RS29415	COG4152	abc transporter atp-binding protein
J3U87_RS29430	COG3604	Transcriptional regulator
J3U87_RS29485	COG2433	Pfam Transposase IS66
J3U87_RS29530	COG0515	serine threonine protein kinase
J3U87_RS29530	COG2815	serine threonine protein kinase
J3U87_RS29585	COG0515	serine threonine protein kinase
J3U87_RS29595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J3U87_RS29600	COG5000	phosphorelay sensor kinase activity
J3U87_RS29605	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J3U87_RS29620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J3U87_RS29620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J3U87_RS29655	COG0784	Response regulator, receiver
J3U87_RS29655	COG2205	protein histidine kinase activity
J3U87_RS29670	COG1132	(ABC) transporter
J3U87_RS29675	COG1132	(ABC) transporter
J3U87_RS29690	COG1131	(ABC) transporter
J3U87_RS29730	COG4771	TonB-dependent receptor
J3U87_RS29740	COG0659	secondary active sulfate transmembrane transporter activity
J3U87_RS29750	COG2207	Transcriptional regulator
J3U87_RS29765	COG4771	TonB-dependent receptor
J3U87_RS29780	COG0523	cobalamin synthesis protein
J3U87_RS29815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J3U87_RS29835	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
J3U87_RS29840	COG0116	Belongs to the methyltransferase superfamily
J3U87_RS29840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J3U87_RS29855	COG1192	Involved in chromosome partitioning
J3U87_RS29860	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J3U87_RS29865	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J3U87_RS29910	COG0784	Response regulator, receiver
J3U87_RS29910	COG5002	protein histidine kinase activity
J3U87_RS29915	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J3U87_RS29950	COG1607	acyl-coa hydrolase
J3U87_RS29990	COG3292	Two component regulator propeller
J3U87_RS29990	COG2205	protein histidine kinase activity
J3U87_RS29990	COG0745	RESPONSE REGULATOR receiver
J3U87_RS29995	COG4771	TonB-dependent receptor
J3U87_RS30005	COG4774	siderophore transport
J3U87_RS30025	COG1136	(ABC) transporter
J3U87_RS30030	COG0577	efflux transmembrane transporter activity
J3U87_RS30035	COG1136	(ABC) transporter
J3U87_RS30035	COG0577	efflux transmembrane transporter activity
J3U87_RS30040	COG2204	response regulator
J3U87_RS30045	COG4191	Histidine kinase
J3U87_RS30105	COG1131	(ABC) transporter
J3U87_RS30150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS30170	COG1960	acyl-CoA dehydrogenase activity
J3U87_RS30175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J3U87_RS30185	COG1309	transcriptional regulator
J3U87_RS30225	COG0515	serine threonine protein kinase
J3U87_RS30225	COG2815	serine threonine protein kinase
J3U87_RS30270	COG0745	RESPONSE REGULATOR receiver
J3U87_RS30300	COG0254	rRNA binding
J3U87_RS30305	COG4589	Belongs to the CDS family
J3U87_RS30315	COG0714	Associated with various cellular activities
J3U87_RS30320	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J3U87_RS30325	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J3U87_RS30330	COG0045	succinate-CoA ligase (ADP-forming) activity
J3U87_RS30335	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J3U87_RS30340	COG0105	UTP biosynthetic process
J3U87_RS30345	COG3590	peptidase
J3U87_RS30405	COG0612	Peptidase, M16
J3U87_RS30410	COG2204	response regulator
J3U87_RS30435	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J3U87_RS30460	COG2111	Na H antiporter
J3U87_RS30460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J3U87_RS30465	COG2111	Na H antiporter
J3U87_RS30470	COG1006	Multisubunit Na H antiporter MnhC subunit
J3U87_RS30475	COG0651	ATP synthesis coupled electron transport
J3U87_RS30480	COG1863	multisubunit Na H antiporter MnhE subunit
J3U87_RS30485	COG2212	antiporter activity
J3U87_RS30490	COG1320	monovalent cation:proton antiporter activity
J3U87_RS30495	COG3273	potassium ion transport
J3U87_RS30495	COG0471	metal ion transport
J3U87_RS30530	COG0745	RESPONSE REGULATOR receiver
J3U87_RS30535	COG0511	ligase activity, forming carbon-carbon bonds
J3U87_RS30540	COG0439	Biotin carboxylase
J3U87_RS30545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J3U87_RS30590	COG3292	Two component regulator propeller
J3U87_RS30590	COG0745	RESPONSE REGULATOR receiver
J3U87_RS30590	COG2205	protein histidine kinase activity
J3U87_RS30590	COG3292	Two component regulator propeller
J3U87_RS30590	COG2205	protein histidine kinase activity
J3U87_RS30590	COG0745	RESPONSE REGULATOR receiver
J3U87_RS30595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J3U87_RS30610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J3U87_RS30615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J3U87_RS30620	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J3U87_RS30635	COG3290	protein histidine kinase activity
J3U87_RS30645	COG0515	serine threonine protein kinase
J3U87_RS30645	COG2815	serine threonine protein kinase
J3U87_RS30665	COG5002	protein histidine kinase activity
J3U87_RS30665	COG2198	Histidine kinase
J3U87_RS30665	COG0784	Response regulator, receiver
J3U87_RS30680	COG0546	phosphoglycolate phosphatase activity
J3U87_RS30700	COG2936	dipeptidyl-peptidase activity
J3U87_RS30710	COG2815	serine threonine protein kinase
J3U87_RS30710	COG0515	serine threonine protein kinase
J3U87_RS30740	COG2205	protein histidine kinase activity
J3U87_RS30745	COG0745	RESPONSE REGULATOR receiver
J3U87_RS30755	COG3339	Conserved Protein
J3U87_RS30760	COG0840	transmembrane signaling receptor activity
J3U87_RS30775	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J3U87_RS30780	COG0052	Belongs to the universal ribosomal protein uS2 family
J3U87_RS30785	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J3U87_RS30790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J3U87_RS30795	COG1668	transmembrane transport
J3U87_RS30800	COG4555	ABC transporter
J3U87_RS30825	COG0625	glutathione transferase activity
J3U87_RS30835	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J3U87_RS30840	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J3U87_RS30885	COG1725	Transcriptional regulator
J3U87_RS30915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J3U87_RS30925	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS30950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J3U87_RS30995	COG3321	synthase
J3U87_RS30995	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS30995	COG0604	alcohol dehydrogenase
J3U87_RS31025	COG3842	ATPase activity
J3U87_RS31030	COG0395	ABC-type sugar transport system, permease component
J3U87_RS31035	COG1175	transmembrane transport
J3U87_RS31040	COG1653	transport
J3U87_RS31050	COG2815	serine threonine protein kinase
J3U87_RS31050	COG0515	serine threonine protein kinase
J3U87_RS31120	COG1228	amidohydrolase
J3U87_RS31165	COG2382	esterase
J3U87_RS31175	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J3U87_RS31205	COG2267	carboxylic ester hydrolase activity
J3U87_RS31225	COG0529	Catalyzes the synthesis of activated sulfate
J3U87_RS31225	COG2895	sulfate adenylyltransferase (ATP) activity
J3U87_RS31230	COG0175	sulfate reduction
J3U87_RS31235	COG0529	Catalyzes the synthesis of activated sulfate
J3U87_RS31255	COG2815	serine threonine protein kinase
J3U87_RS31255	COG0515	serine threonine protein kinase
J3U87_RS31285	COG4249	Peptidase C14 caspase catalytic subunit p20
J3U87_RS31285	COG2319	Wd-40 repeat
J3U87_RS31305	COG1032	radical SAM domain protein
J3U87_RS31320	COG5002	protein histidine kinase activity
J3U87_RS31335	COG0583	DNA-binding transcription factor activity
J3U87_RS31360	COG3534	alpha-L-arabinofuranosidase
J3U87_RS31405	COG2169	Transcriptional regulator
J3U87_RS31405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J3U87_RS31415	COG1454	alcohol dehydrogenase
J3U87_RS31430	COG0688	phosphatidylethanolamine metabolic process
J3U87_RS31435	COG1683	Conserved Protein
J3U87_RS31475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS31495	COG4335	DNA alkylation repair
J3U87_RS31525	COG4771	TonB-dependent receptor
J3U87_RS31540	COG4977	sequence-specific DNA binding
J3U87_RS31550	COG2010	Cytochrome c
J3U87_RS31555	COG3256	nitric oxide reductase
J3U87_RS31600	COG0243	molybdopterin cofactor binding
J3U87_RS31650	COG1459	type II secretion system
J3U87_RS31655	COG4968	Prepilin-type N-terminal cleavage methylation domain
J3U87_RS31665	COG1450	Type ii and iii secretion system protein
J3U87_RS31775	COG1131	(ABC) transporter
J3U87_RS31780	COG3275	phosphorelay sensor kinase activity
J3U87_RS31785	COG3279	Response regulator of the LytR AlgR family
J3U87_RS31815	COG2319	Wd-40 repeat
J3U87_RS31815	COG4249	Peptidase C14 caspase catalytic subunit p20
J3U87_RS31835	COG0640	Transcriptional regulator
J3U87_RS31860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J3U87_RS31905	COG0515	serine threonine protein kinase
J3U87_RS31905	COG2815	serine threonine protein kinase
J3U87_RS31910	COG2205	protein histidine kinase activity
J3U87_RS31910	COG0784	Response regulator, receiver
J3U87_RS31915	COG2204	response regulator
J3U87_RS31925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J3U87_RS31930	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS31930	COG3321	synthase
J3U87_RS31930	COG4221	oxidoreductase activity
J3U87_RS31930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS31935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS31935	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS31935	COG3321	synthase
J3U87_RS31935	COG4221	oxidoreductase activity
J3U87_RS31935	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS31935	COG3321	synthase
J3U87_RS31935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS31935	COG4221	oxidoreductase activity
J3U87_RS31940	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS31940	COG3321	synthase
J3U87_RS31940	COG4221	oxidoreductase activity
J3U87_RS31940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS31945	COG3321	synthase
J3U87_RS31945	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS31945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS31945	COG0318	PFAM AMP-dependent synthetase and ligase
J3U87_RS31945	COG0300	oxidoreductase activity
J3U87_RS31955	COG4221	oxidoreductase activity
J3U87_RS31955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS31955	COG4221	oxidoreductase activity
J3U87_RS31955	COG3321	synthase
J3U87_RS31955	COG0300	oxidoreductase activity
J3U87_RS31955	COG0300	oxidoreductase activity
J3U87_RS31955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS31955	COG3321	synthase
J3U87_RS31960	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS31960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS31960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS31960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS31960	COG3321	synthase
J3U87_RS31985	COG1404	Belongs to the peptidase S8 family
J3U87_RS31990	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
J3U87_RS32005	COG5002	protein histidine kinase activity
J3U87_RS32005	COG0784	Response regulator, receiver
J3U87_RS32005	COG2205	protein histidine kinase activity
J3U87_RS32010	COG4771	TonB-dependent receptor
J3U87_RS32020	COG5001	Diguanylate cyclase
J3U87_RS32020	COG4251	negative regulation of phosphorylation
J3U87_RS32020	COG3706	GGDEF domain
J3U87_RS32020	COG2203	Gaf domain
J3U87_RS32025	COG2226	methyltransferase
J3U87_RS32100	COG3220	belongs to the UPF0276 family
J3U87_RS32110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J3U87_RS32120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J3U87_RS32130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J3U87_RS32145	COG4771	TonB-dependent receptor
J3U87_RS32150	COG0616	signal peptide processing
J3U87_RS32180	COG0583	DNA-binding transcription factor activity
J3U87_RS32185	COG1902	pentaerythritol trinitrate reductase activity
J3U87_RS32205	COG1335	isochorismatase
J3U87_RS32230	COG4771	TonB-dependent receptor
J3U87_RS32250	COG3227	Zinc metalloprotease (Elastase)
J3U87_RS32295	COG2267	carboxylic ester hydrolase activity
J3U87_RS32305	COG0745	RESPONSE REGULATOR receiver
J3U87_RS32310	COG2234	aminopeptidase activity
J3U87_RS32365	COG0137	argininosuccinate synthase activity
J3U87_RS32370	COG1438	arginine binding
J3U87_RS32380	COG1024	Enoyl-CoA hydratase
J3U87_RS32390	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J3U87_RS32400	COG0183	Belongs to the thiolase family
J3U87_RS32405	COG1024	Enoyl-CoA hydratase
J3U87_RS32405	COG1250	3-hydroxyacyl-CoA dehydrogenase
J3U87_RS32410	COG1022	Amp-dependent synthetase and ligase
J3U87_RS32415	COG1960	acyl-CoA dehydrogenase activity
J3U87_RS32420	COG5002	protein histidine kinase activity
J3U87_RS32470	COG1611	Belongs to the LOG family
J3U87_RS32475	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J3U87_RS32515	COG1032	radical SAM domain protein
J3U87_RS32530	COG2205	protein histidine kinase activity
J3U87_RS32555	COG4771	TonB-dependent receptor
J3U87_RS32560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS32610	COG1253	flavin adenine dinucleotide binding
J3U87_RS32615	COG3290	protein histidine kinase activity
J3U87_RS32620	COG0515	serine threonine protein kinase
J3U87_RS32620	COG2815	serine threonine protein kinase
J3U87_RS32630	COG0745	RESPONSE REGULATOR receiver
J3U87_RS32630	COG2205	protein histidine kinase activity
J3U87_RS32630	COG3292	Two component regulator propeller
J3U87_RS32635	COG0457	Tetratricopeptide repeat
J3U87_RS32635	COG0705	Rhomboid family
J3U87_RS32640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J3U87_RS32680	COG3437	response regulator, receiver
J3U87_RS32685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J3U87_RS32685	COG1648	precorrin-2 dehydrogenase activity
J3U87_RS32690	COG0535	radical SAM domain protein
J3U87_RS32725	COG1648	precorrin-2 dehydrogenase activity
J3U87_RS32725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J3U87_RS32735	COG2866	Carboxypeptidase
J3U87_RS32765	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J3U87_RS32775	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS32780	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J3U87_RS32785	COG0083	homoserine kinase activity
J3U87_RS32790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J3U87_RS32835	COG0432	Pfam Uncharacterised protein family UPF0047
J3U87_RS32840	COG0305	Participates in initiation and elongation during chromosome replication
J3U87_RS32845	COG0318	PFAM AMP-dependent synthetase and ligase
J3U87_RS32850	COG0596	Alpha beta hydrolase
J3U87_RS32855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J3U87_RS32865	COG0667	Aldo Keto reductase
J3U87_RS32870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J3U87_RS32880	COG4946	Tricorn protease homolog
J3U87_RS32880	COG0793	Belongs to the peptidase S41A family
J3U87_RS32890	COG2226	methyltransferase
J3U87_RS32935	COG1476	TRANSCRIPTIONal
J3U87_RS32950	COG1132	(ABC) transporter
J3U87_RS32985	COG1752	Esterase of the alpha-beta hydrolase superfamily
J3U87_RS33010	COG2815	serine threonine protein kinase
J3U87_RS33010	COG0515	serine threonine protein kinase
J3U87_RS33025	COG0515	serine threonine protein kinase
J3U87_RS33065	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J3U87_RS33075	COG0640	Transcriptional regulator
J3U87_RS33095	COG0625	glutathione transferase activity
J3U87_RS33115	COG4638	Rieske (2fe-2S)
J3U87_RS33170	COG1309	transcriptional regulator
J3U87_RS33200	COG2205	protein histidine kinase activity
J3U87_RS33200	COG0784	Response regulator, receiver
J3U87_RS33210	COG0789	Transcriptional regulator
J3U87_RS33215	COG1131	(ABC) transporter
J3U87_RS33310	COG0431	NADPH-dependent FMN reductase
J3U87_RS33315	COG2818	Glycosylase
J3U87_RS33335	COG3842	ATPase activity
J3U87_RS33340	COG1176	ABC-type spermidine putrescine transport system, permease component I
J3U87_RS33345	COG1177	transmembrane transport
J3U87_RS33350	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J3U87_RS33360	COG0577	efflux transmembrane transporter activity
J3U87_RS33370	COG1136	(ABC) transporter
J3U87_RS33370	COG0577	efflux transmembrane transporter activity
J3U87_RS33380	COG0300	oxidoreductase activity
J3U87_RS33380	COG0318	PFAM AMP-dependent synthetase and ligase
J3U87_RS33380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS33380	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS33380	COG3321	synthase
J3U87_RS33385	COG3321	synthase
J3U87_RS33385	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
J3U87_RS33385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS33385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J3U87_RS33400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS33400	COG3321	synthase
J3U87_RS33400	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS33400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS33400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS33405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS33405	COG0300	oxidoreductase activity
J3U87_RS33405	COG3321	synthase
J3U87_RS33405	COG4221	oxidoreductase activity
J3U87_RS33410	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS33410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J3U87_RS33410	COG3321	synthase
J3U87_RS33410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS33410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J3U87_RS33415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J3U87_RS33415	COG2070	2-Nitropropane dioxygenase
J3U87_RS33425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J3U87_RS33460	COG2885	chlorophyll binding
J3U87_RS33560	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J3U87_RS33570	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
J3U87_RS33580	COG0617	tRNA 3'-terminal CCA addition
J3U87_RS33585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J3U87_RS33595	COG0116	Belongs to the methyltransferase superfamily
J3U87_RS33595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J3U87_RS33600	COG0631	protein serine/threonine phosphatase activity
J3U87_RS33620	COG0642	Histidine kinase
J3U87_RS33625	COG0745	RESPONSE REGULATOR receiver
J3U87_RS33630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J3U87_RS33635	COG1566	PFAM secretion protein HlyD family protein
J3U87_RS33680	COG0784	Response regulator, receiver
J3U87_RS33685	COG4251	negative regulation of phosphorylation
J3U87_RS33690	COG0666	response to abiotic stimulus
J3U87_RS33695	COG0784	Response regulator, receiver
J3U87_RS33700	COG5001	Diguanylate cyclase
J3U87_RS33700	COG5002	protein histidine kinase activity
J3U87_RS33710	COG4251	negative regulation of phosphorylation
J3U87_RS33770	COG1233	COG1233 Phytoene dehydrogenase and related
J3U87_RS33815	COG0390	transport system, permease component
J3U87_RS33820	COG3842	ATPase activity
J3U87_RS33830	COG2188	Transcriptional regulator
J3U87_RS33835	COG1131	(ABC) transporter
J3U87_RS33845	COG1131	(ABC) transporter
J3U87_RS33875	COG0515	serine threonine protein kinase
J3U87_RS33875	COG2815	serine threonine protein kinase
J3U87_RS33880	COG0793	Belongs to the peptidase S41A family
J3U87_RS33880	COG4946	Tricorn protease homolog
J3U87_RS33920	COG0583	DNA-binding transcription factor activity
J3U87_RS33925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J3U87_RS33930	COG1309	transcriptional regulator
J3U87_RS33935	COG4191	Histidine kinase
J3U87_RS33950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J3U87_RS33970	COG2207	Transcriptional regulator
J3U87_RS34000	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J3U87_RS34005	COG0745	RESPONSE REGULATOR receiver
J3U87_RS34005	COG2205	protein histidine kinase activity
J3U87_RS34005	COG3292	Two component regulator propeller
J3U87_RS34015	COG1028	Short-chain dehydrogenase reductase Sdr
J3U87_RS34025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J3U87_RS34030	COG1538	Outer membrane efflux protein
J3U87_RS34035	COG1309	transcriptional regulator
J3U87_RS34080	COG1404	Belongs to the peptidase S8 family
J3U87_RS34085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J3U87_RS34095	COG2205	protein histidine kinase activity
J3U87_RS34120	COG2165	general secretion pathway protein
J3U87_RS34125	COG0488	(ABC) transporter
J3U87_RS34130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J3U87_RS34140	COG1538	Outer membrane efflux protein
J3U87_RS34145	COG1309	transcriptional regulator
J3U87_RS34150	COG1605	Chorismate mutase
J3U87_RS34150	COG0287	Prephenate dehydrogenase
J3U87_RS34160	COG5002	protein histidine kinase activity
J3U87_RS34165	COG0745	RESPONSE REGULATOR receiver
J3U87_RS34180	COG1733	regulation of RNA biosynthetic process
J3U87_RS34195	COG2423	ornithine cyclodeaminase activity
J3U87_RS34225	COG1476	TRANSCRIPTIONal
J3U87_RS34280	COG0484	heat shock protein binding
J3U87_RS34300	COG0515	serine threonine protein kinase
J3U87_RS34300	COG2815	serine threonine protein kinase
J3U87_RS34375	COG3436	PFAM IS66 Orf2 family protein
J3U87_RS34380	COG4372	Transposase
J3U87_RS34450	COG4974	Belongs to the 'phage' integrase family
J3U87_RS34455	COG4974	Belongs to the 'phage' integrase family
J3U87_RS34500	COG0582	viral genome integration into host DNA
J3U87_RS34540	COG0515	serine threonine protein kinase
J3U87_RS34540	COG2815	serine threonine protein kinase
J3U87_RS34555	COG1106	Psort location Cytoplasmic, score
J3U87_RS34620	COG2340	Cysteine-rich secretory protein family
J3U87_RS34635	COG2385	sporulation resulting in formation of a cellular spore
J3U87_RS34635	COG2385	sporulation resulting in formation of a cellular spore
J3U87_RS34640	COG0848	biopolymer transport protein
J3U87_RS34645	COG0811	peptide transport
J3U87_RS34650	COG0823	Involved in the tonB-independent uptake of proteins
J3U87_RS34650	COG1506	peptidase
J3U87_RS34685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J3U87_RS34690	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J3U87_RS34690	COG0140	phosphoribosyl-ATP diphosphatase activity
J3U87_RS34695	COG0107	imidazoleglycerol-phosphate synthase activity
J3U87_RS34700	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J3U87_RS34705	COG0131	Imidazoleglycerol-phosphate dehydratase
J3U87_RS34710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J3U87_RS34715	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J3U87_RS34730	COG0495	leucyl-tRNA aminoacylation
J3U87_RS34740	COG2855	membrane
J3U87_RS34750	COG3290	protein histidine kinase activity
J3U87_RS34755	COG3485	protocatechuate 3,4-dioxygenase
J3U87_RS34765	COG1215	transferase activity, transferring glycosyl groups
J3U87_RS34780	COG0557	exoribonuclease II activity
J3U87_RS34790	COG0534	Mate efflux family protein
J3U87_RS34800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J3U87_RS34830	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J3U87_RS34835	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J3U87_RS34895	COG1132	(ABC) transporter
J3U87_RS34900	COG0604	alcohol dehydrogenase
J3U87_RS34900	COG3321	synthase
J3U87_RS34920	COG0606	chelatase, subunit chli
J3U87_RS34925	COG0220	tRNA (guanine-N7-)-methyltransferase activity