locus-tag	class	description
BOO69_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BOO69_RS00010	COG0268	Binds directly to 16S ribosomal RNA
BOO69_RS00015	COG1024	Enoyl-CoA hydratase
BOO69_RS00020	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BOO69_RS00025	COG2226	methyltransferase
BOO69_RS00035	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BOO69_RS00040	COG0747	negative chemotaxis
BOO69_RS00060	COG2116	formate transmembrane transporter activity
BOO69_RS00065	COG1295	ribonuclease BN
BOO69_RS00090	COG0784	Response regulator, receiver
BOO69_RS00115	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BOO69_RS00120	COG0069	glutamate synthase activity
BOO69_RS00125	COG2358	TRAP transporter, solute receptor (TAXI family
BOO69_RS00145	COG1181	Belongs to the D-alanine--D-alanine ligase family
BOO69_RS00155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOO69_RS00160	COG0693	protein deglycase activity
BOO69_RS00170	COG2995	paraquat-inducible protein a
BOO69_RS00175	COG3008	intermembrane lipid transfer
BOO69_RS00355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BOO69_RS00365	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BOO69_RS00375	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BOO69_RS00380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BOO69_RS00415	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BOO69_RS00420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BOO69_RS00460	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BOO69_RS00485	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BOO69_RS00495	COG1722	exodeoxyribonuclease VII activity
BOO69_RS00500	COG0745	RESPONSE REGULATOR receiver
BOO69_RS00505	COG1846	Transcriptional regulator
BOO69_RS00510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BOO69_RS00530	COG2197	response regulator
BOO69_RS00545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BOO69_RS00550	COG4143	(ABC) transporter
BOO69_RS00560	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BOO69_RS00570	COG2808	Putative FMN-binding domain
BOO69_RS00575	COG0625	glutathione transferase activity
BOO69_RS00600	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BOO69_RS00705	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BOO69_RS00725	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BOO69_RS00725	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BOO69_RS00735	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BOO69_RS00740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOO69_RS00765	COG1414	Transcriptional regulator
BOO69_RS00770	COG3214	Protein conserved in bacteria
BOO69_RS00775	COG1609	Transcriptional regulator
BOO69_RS00805	COG0697	spore germination
BOO69_RS00810	COG0473	3-isopropylmalate dehydrogenase activity
BOO69_RS00825	COG0066	3-isopropylmalate dehydratase activity
BOO69_RS00835	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BOO69_RS00840	COG3264	Mechanosensitive ion channel
BOO69_RS00840	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BOO69_RS00850	COG0799	negative regulation of ribosome biogenesis
BOO69_RS00855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BOO69_RS00870	COG0277	FAD linked oxidase domain protein
BOO69_RS00875	COG0277	FAD linked oxidase domain protein
BOO69_RS00885	COG0247	lactate metabolic process
BOO69_RS00910	COG1012	belongs to the aldehyde dehydrogenase family
BOO69_RS01000	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BOO69_RS01005	COG0625	glutathione transferase activity
BOO69_RS01010	COG2897	thiosulfate sulfurtransferase activity
BOO69_RS01025	COG0004	ammonium transporteR
BOO69_RS01035	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BOO69_RS01040	COG0384	phenazine biosynthesis protein PhzF
BOO69_RS01050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOO69_RS01070	COG2154	pterin-4-alpha-carbinolamine dehydratase
BOO69_RS01075	COG0668	transmembrane transport
BOO69_RS01080	COG0678	peroxiredoxin activity
BOO69_RS01090	COG0742	ribosomal rna small subunit methyltransferase
BOO69_RS01095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOO69_RS01105	COG0024	Methionine aminopeptidase
BOO69_RS01110	COG1489	DNA binding
BOO69_RS01115	COG1058	Belongs to the CinA family
BOO69_RS01115	COG1546	Belongs to the CinA family
BOO69_RS01135	COG0583	DNA-binding transcription factor activity
BOO69_RS01145	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOO69_RS01145	COG1902	pentaerythritol trinitrate reductase activity
BOO69_RS01155	COG1051	belongs to the nudix hydrolase family
BOO69_RS01170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BOO69_RS01175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BOO69_RS01180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BOO69_RS01180	COG2169	Transcriptional regulator
BOO69_RS01185	COG2885	chlorophyll binding
BOO69_RS01195	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BOO69_RS01205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOO69_RS01205	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BOO69_RS01210	COG0697	spore germination
BOO69_RS01215	COG0741	lytic transglycosylase activity
BOO69_RS01220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BOO69_RS01225	COG1473	amidohydrolase
BOO69_RS01235	COG0437	4 iron, 4 sulfur cluster binding
BOO69_RS01240	COG0243	molybdopterin cofactor binding
BOO69_RS01255	COG0028	Belongs to the TPP enzyme family
BOO69_RS01260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOO69_RS01270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BOO69_RS01285	COG1116	anion transmembrane transporter activity
BOO69_RS01290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BOO69_RS01320	COG0587	DNA-directed DNA polymerase activity
BOO69_RS01330	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BOO69_RS01335	COG1280	lysine exporter protein (LysE YggA)
BOO69_RS01370	COG0825	malonyl-CoA metabolic process
BOO69_RS01375	COG2301	Belongs to the HpcH HpaI aldolase family
BOO69_RS01385	COG4948	Mandelate Racemase Muconate Lactonizing
BOO69_RS01415	COG0335	large ribosomal subunit rRNA binding
BOO69_RS01420	COG0254	rRNA binding
BOO69_RS01435	COG0489	protein tyrosine kinase activity
BOO69_RS01435	COG2151	metal-sulfur cluster biosynthetic enzyme
BOO69_RS01440	COG0336	Belongs to the RNA methyltransferase TrmD family
BOO69_RS01450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BOO69_RS01455	COG0778	Nitroreductase
BOO69_RS01460	COG0228	four-way junction DNA binding
BOO69_RS01470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BOO69_RS01475	COG0471	metal ion transport
BOO69_RS01475	COG3273	potassium ion transport
BOO69_RS01480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BOO69_RS01505	COG0583	DNA-binding transcription factor activity
BOO69_RS01515	COG0356	it plays a direct role in the translocation of protons across the membrane
BOO69_RS01520	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BOO69_RS01530	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BOO69_RS01560	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BOO69_RS01575	COG0435	Glutathione S-transferase
BOO69_RS01585	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BOO69_RS01590	COG0242	peptide deformylase activity
BOO69_RS01595	COG0242	peptide deformylase activity
BOO69_RS01600	COG0242	peptide deformylase activity
BOO69_RS01605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BOO69_RS01615	COG2860	membrane
BOO69_RS01620	COG0328	RNA-DNA hybrid ribonuclease activity
BOO69_RS01625	COG4106	trans-aconitate 2-methyltransferase activity
BOO69_RS01640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BOO69_RS01645	COG2197	response regulator
BOO69_RS01655	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BOO69_RS01660	COG1758	RNA polymerase activity
BOO69_RS01665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BOO69_RS01675	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BOO69_RS01685	COG0736	holo-[acyl-carrier-protein] synthase activity
BOO69_RS01690	COG0681	Belongs to the peptidase S26 family
BOO69_RS01695	COG0571	ribonuclease III activity
BOO69_RS01700	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BOO69_RS01710	COG1381	Involved in DNA repair and RecF pathway recombination
BOO69_RS01735	COG1396	sequence-specific DNA binding
BOO69_RS01750	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BOO69_RS01755	COG0745	RESPONSE REGULATOR receiver
BOO69_RS01760	COG2205	protein histidine kinase activity
BOO69_RS01770	COG1660	Displays ATPase and GTPase activities
BOO69_RS01780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOO69_RS01790	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOO69_RS01810	COG2096	Adenosyltransferase
BOO69_RS01820	COG0300	oxidoreductase activity
BOO69_RS01830	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BOO69_RS01840	COG0501	Belongs to the peptidase M48B family
BOO69_RS01850	COG2124	cytochrome p450
BOO69_RS01860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BOO69_RS01890	COG0250	Participates in transcription elongation, termination and antitermination
BOO69_RS01900	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BOO69_RS01905	COG0081	regulation of translation
BOO69_RS01915	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BOO69_RS01920	COG0222	ribosome binding
BOO69_RS01925	COG0085	RNA polymerase activity
BOO69_RS01930	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BOO69_RS01935	COG0697	spore germination
BOO69_RS01945	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BOO69_RS01950	COG0049	tRNA binding
BOO69_RS01955	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BOO69_RS01960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BOO69_RS01970	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BOO69_RS01975	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BOO69_RS01980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BOO69_RS01985	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BOO69_RS01990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BOO69_RS01995	COG0089	rRNA binding
BOO69_RS02000	COG0088	Forms part of the polypeptide exit tunnel
BOO69_RS02005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BOO69_RS02010	COG0051	transcription antitermination factor activity, RNA binding
BOO69_RS02030	COG0255	Belongs to the universal ribosomal protein uL29 family
BOO69_RS02035	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BOO69_RS02040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BOO69_RS02045	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BOO69_RS02050	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BOO69_RS02055	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BOO69_RS02060	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BOO69_RS02065	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BOO69_RS02070	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BOO69_RS02075	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BOO69_RS02080	COG1841	ribosomal large subunit assembly
BOO69_RS02100	COG0200	Binds to the 23S rRNA
BOO69_RS02105	COG0201	protein transport
BOO69_RS02110	COG0563	adenylate kinase activity
BOO69_RS02115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BOO69_RS02120	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BOO69_RS02125	COG0202	RNA polymerase activity
BOO69_RS02130	COG0203	ribosomal protein L17
BOO69_RS02135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BOO69_RS02140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BOO69_RS02145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BOO69_RS02150	COG0564	pseudouridine synthase activity
BOO69_RS02155	COG0546	phosphoglycolate phosphatase activity
BOO69_RS02165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOO69_RS02170	COG4597	amino acid ABC transporter
BOO69_RS02180	COG1126	abc transporter atp-binding protein
BOO69_RS02185	COG2062	phosphohistidine phosphatase, SixA
BOO69_RS02195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BOO69_RS02200	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BOO69_RS02210	COG0706	membrane insertase activity
BOO69_RS02220	COG0037	tRNA processing
BOO69_RS02230	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BOO69_RS02235	COG0594	ribonuclease P activity
BOO69_RS02240	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BOO69_RS02250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BOO69_RS02255	COG5000	phosphorelay sensor kinase activity
BOO69_RS02270	COG4605	iron ion homeostasis
BOO69_RS02310	COG5002	protein histidine kinase activity
BOO69_RS02320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BOO69_RS02340	COG4638	Rieske (2fe-2S)
BOO69_RS02355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BOO69_RS02360	COG0235	Class ii aldolase
BOO69_RS02365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BOO69_RS02375	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BOO69_RS02380	COG0183	Belongs to the thiolase family
BOO69_RS02385	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS02390	COG1024	Enoyl-CoA hydratase
BOO69_RS02395	COG1309	transcriptional regulator
BOO69_RS02400	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS02415	COG0183	Belongs to the thiolase family
BOO69_RS02420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOO69_RS02420	COG0604	alcohol dehydrogenase
BOO69_RS02420	COG3321	synthase
BOO69_RS02420	COG4221	oxidoreductase activity
BOO69_RS02450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BOO69_RS02460	COG1376	ErfK ybiS ycfS ynhG family protein
BOO69_RS02460	COG1388	LysM domain
BOO69_RS02465	COG0539	negative regulation of cytoplasmic translation
BOO69_RS02470	COG0776	regulation of translation
BOO69_RS02480	COG0135	phosphoribosylanthranilate isomerase activity
BOO69_RS02485	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BOO69_RS02490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BOO69_RS02500	COG1183	phosphatidylcholine synthase activity
BOO69_RS02505	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BOO69_RS02535	COG2244	polysaccharide biosynthetic process
BOO69_RS02545	COG0784	Response regulator, receiver
BOO69_RS02545	COG2198	Histidine kinase
BOO69_RS02545	COG5002	protein histidine kinase activity
BOO69_RS02560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BOO69_RS02585	COG0583	DNA-binding transcription factor activity
BOO69_RS02590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BOO69_RS02595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BOO69_RS02600	COG0424	maF-like protein
BOO69_RS02605	COG1530	ribonuclease E activity
BOO69_RS02610	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BOO69_RS02645	COG2274	protein secretion by the type I secretion system
BOO69_RS02650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOO69_RS02670	COG0784	Response regulator, receiver
BOO69_RS02670	COG2198	Histidine kinase
BOO69_RS02670	COG2205	protein histidine kinase activity
BOO69_RS02670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOO69_RS02700	COG0745	RESPONSE REGULATOR receiver
BOO69_RS02735	COG4974	Belongs to the 'phage' integrase family
BOO69_RS02740	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
BOO69_RS02745	COG1431	PFAM Stem cell self-renewal protein Piwi
BOO69_RS02750	COG1078	dGTPase activity
BOO69_RS02780	COG0179	Fumarylacetoacetate (FAA) hydrolase
BOO69_RS02795	COG0625	glutathione transferase activity
BOO69_RS02810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BOO69_RS02840	COG0693	protein deglycase activity
BOO69_RS02845	COG1879	ABC-type sugar transport system periplasmic component
BOO69_RS02850	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOO69_RS02855	COG1129	ABC transporter
BOO69_RS02865	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BOO69_RS02870	COG1454	alcohol dehydrogenase
BOO69_RS02880	COG0657	acetylesterase activity
BOO69_RS02890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BOO69_RS02915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BOO69_RS02925	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS02945	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BOO69_RS02955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS02960	COG0601	transmembrane transport
BOO69_RS02965	COG0747	negative chemotaxis
BOO69_RS02970	COG0028	Belongs to the TPP enzyme family
BOO69_RS02975	COG1609	Transcriptional regulator
BOO69_RS02980	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOO69_RS02985	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS03000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BOO69_RS03020	COG0028	Belongs to the TPP enzyme family
BOO69_RS03025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOO69_RS03040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BOO69_RS03045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BOO69_RS03065	COG2010	Cytochrome c
BOO69_RS03070	COG0348	domain, Protein
BOO69_RS03080	COG2217	Heavy metal translocating P-type atpase
BOO69_RS03120	COG0174	glutamine synthetase
BOO69_RS03140	COG2130	NADP-dependent
BOO69_RS03145	COG0406	alpha-ribazole phosphatase activity
BOO69_RS03155	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS03160	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS03170	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS03175	COG0183	Belongs to the thiolase family
BOO69_RS03230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BOO69_RS03235	COG1946	Acyl-CoA thioesterase
BOO69_RS03245	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS03250	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS03260	COG1024	Enoyl-CoA hydratase
BOO69_RS03265	COG1024	Enoyl-CoA hydratase
BOO69_RS03265	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOO69_RS03270	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS03275	COG2111	Na H antiporter
BOO69_RS03275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BOO69_RS03280	COG1006	Multisubunit Na H antiporter MnhC subunit
BOO69_RS03285	COG0651	ATP synthesis coupled electron transport
BOO69_RS03290	COG1863	multisubunit Na H antiporter MnhE subunit
BOO69_RS03295	COG2212	antiporter activity
BOO69_RS03345	COG0179	Fumarylacetoacetate (FAA) hydrolase
BOO69_RS03350	COG3971	2-oxopent-4-enoate hydratase activity
BOO69_RS03365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOO69_RS03375	COG0179	Fumarylacetoacetate (FAA) hydrolase
BOO69_RS03380	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BOO69_RS03395	COG0745	RESPONSE REGULATOR receiver
BOO69_RS03400	COG2205	protein histidine kinase activity
BOO69_RS03405	COG1271	oxidase subunit
BOO69_RS03410	COG1294	oxidase, subunit
BOO69_RS03425	COG0697	spore germination
BOO69_RS03435	COG1131	(ABC) transporter
BOO69_RS03440	COG0842	Transport permease protein
BOO69_RS03455	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS03460	COG0322	excinuclease ABC activity
BOO69_RS03465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BOO69_RS03475	COG0314	molybdopterin synthase activity
BOO69_RS03520	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BOO69_RS03540	COG0540	Belongs to the ATCase OTCase family
BOO69_RS03545	COG1573	uracil-dna glycosylase
BOO69_RS03550	COG1280	lysine exporter protein (LysE YggA)
BOO69_RS03555	COG0521	Mo-molybdopterin cofactor biosynthetic process
BOO69_RS03565	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BOO69_RS03610	COG2943	transferase activity, transferring hexosyl groups
BOO69_RS03615	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BOO69_RS03630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOO69_RS03635	COG0028	Belongs to the TPP enzyme family
BOO69_RS03650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BOO69_RS03655	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BOO69_RS03660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BOO69_RS03665	COG0306	phosphate transporter
BOO69_RS03675	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BOO69_RS03680	COG0101	tRNA pseudouridine synthase activity
BOO69_RS03695	COG3768	UPF0283 membrane protein
BOO69_RS03715	COG1678	Uncharacterized ACR, COG1678
BOO69_RS03720	COG0009	L-threonylcarbamoyladenylate synthase
BOO69_RS03725	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS03760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BOO69_RS03770	COG1763	Mo-molybdopterin cofactor biosynthetic process
BOO69_RS03775	COG0303	'Molybdopterin
BOO69_RS03785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BOO69_RS03795	COG0789	Transcriptional regulator
BOO69_RS03820	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BOO69_RS03825	COG0142	geranyltranstransferase activity
BOO69_RS03865	COG2200	EAL domain
BOO69_RS03870	COG2818	Glycosylase
BOO69_RS03880	COG3920	Histidine kinase
BOO69_RS03885	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BOO69_RS03895	COG5310	Homospermidine synthase
BOO69_RS03900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BOO69_RS03905	COG0287	Prephenate dehydrogenase
BOO69_RS03920	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BOO69_RS03945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BOO69_RS03965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BOO69_RS03970	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BOO69_RS03975	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BOO69_RS03980	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BOO69_RS03985	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BOO69_RS04005	COG2267	carboxylic ester hydrolase activity
BOO69_RS04015	COG2983	Belongs to the UPF0260 family
BOO69_RS04020	COG0196	riboflavin kinase activity
BOO69_RS04025	COG2030	dehydratase
BOO69_RS04035	COG1227	inorganic diphosphatase activity
BOO69_RS04050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BOO69_RS04055	COG0459	protein refolding
BOO69_RS04075	COG3454	Phosphonate metabolism
BOO69_RS04080	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BOO69_RS04085	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BOO69_RS04095	COG0071	Belongs to the small heat shock protein (HSP20) family
BOO69_RS04105	COG0384	phenazine biosynthesis protein PhzF
BOO69_RS04115	COG0529	Catalyzes the synthesis of activated sulfate
BOO69_RS04115	COG2046	Belongs to the sulfate adenylyltransferase family
BOO69_RS04125	COG0492	ferredoxin-NADP+ reductase activity
BOO69_RS04130	COG1522	sequence-specific DNA binding
BOO69_RS04145	COG1496	oxidoreductase activity
BOO69_RS04155	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BOO69_RS04175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BOO69_RS04180	COG1435	thymidine kinase activity
BOO69_RS04195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BOO69_RS04200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BOO69_RS04205	COG0596	Alpha beta hydrolase
BOO69_RS04225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BOO69_RS04230	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BOO69_RS04250	COG3237	CsbD-like
BOO69_RS04275	COG0280	phosphate acetyltransferase
BOO69_RS04275	COG0281	malic enzyme
BOO69_RS04285	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BOO69_RS04290	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BOO69_RS04295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BOO69_RS04315	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS04365	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOO69_RS04365	COG1024	Enoyl-CoA hydratase
BOO69_RS04375	COG0183	Belongs to the thiolase family
BOO69_RS04380	COG0625	glutathione transferase activity
BOO69_RS04385	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS04395	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS04400	COG0789	Transcriptional regulator
BOO69_RS04405	COG2197	response regulator
BOO69_RS04430	COG0534	Mate efflux family protein
BOO69_RS04455	COG0737	Belongs to the 5'-nucleotidase family
BOO69_RS04460	COG0477	Major facilitator Superfamily
BOO69_RS04465	COG2135	peptidase activity
BOO69_RS04475	COG0583	DNA-binding transcription factor activity
BOO69_RS04480	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS04490	COG4948	Mandelate Racemase Muconate Lactonizing
BOO69_RS04510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BOO69_RS04530	COG1047	Peptidyl-prolyl cis-trans
BOO69_RS04545	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BOO69_RS04550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BOO69_RS04555	COG1012	belongs to the aldehyde dehydrogenase family
BOO69_RS04565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BOO69_RS04570	COG0735	belongs to the Fur family
BOO69_RS04585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BOO69_RS04605	COG1702	phosphate starvation-inducible protein PhoH
BOO69_RS04610	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BOO69_RS04615	COG1253	flavin adenine dinucleotide binding
BOO69_RS04620	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BOO69_RS04625	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BOO69_RS04630	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BOO69_RS04635	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BOO69_RS04640	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BOO69_RS04650	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BOO69_RS04655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BOO69_RS04655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BOO69_RS04665	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BOO69_RS04675	COG1228	amidohydrolase
BOO69_RS04690	COG0366	Alpha amylase catalytic
BOO69_RS04700	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BOO69_RS04710	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BOO69_RS04715	COG1858	cytochrome C peroxidase
BOO69_RS04725	COG1940	carbohydrate kinase activity
BOO69_RS04730	COG4213	ABC transporter substrate-binding protein
BOO69_RS04735	COG4214	carbohydrate transport
BOO69_RS04740	COG1129	ABC transporter
BOO69_RS04745	COG1070	Carbohydrate kinase
BOO69_RS04755	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BOO69_RS04765	COG1522	sequence-specific DNA binding
BOO69_RS04795	COG2080	2 iron, 2 sulfur cluster binding
BOO69_RS04800	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BOO69_RS04820	COG1132	(ABC) transporter
BOO69_RS04825	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS04830	COG0657	acetylesterase activity
BOO69_RS04835	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BOO69_RS04855	COG4172	Belongs to the ABC transporter superfamily
BOO69_RS04860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS04865	COG0601	transmembrane transport
BOO69_RS04900	COG1490	D-aminoacyl-tRNA deacylase activity
BOO69_RS04925	COG3038	cytochrome b561
BOO69_RS04945	COG3853	Toxic anion resistance protein (TelA)
BOO69_RS04960	COG1187	pseudouridine synthase activity
BOO69_RS04965	COG0590	tRNA wobble adenosine to inosine editing
BOO69_RS04980	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BOO69_RS04985	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BOO69_RS04990	COG0154	amidase activity
BOO69_RS05000	COG3023	N-Acetylmuramoyl-L-alanine amidase
BOO69_RS05010	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BOO69_RS05015	COG0670	Belongs to the BI1 family
BOO69_RS05020	COG1396	sequence-specific DNA binding
BOO69_RS05025	COG0483	inositol monophosphate 1-phosphatase activity
BOO69_RS05035	COG0402	S-adenosylhomocysteine deaminase activity
BOO69_RS05040	COG2239	Acts as a magnesium transporter
BOO69_RS05045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BOO69_RS05055	COG1692	metallophosphoesterase
BOO69_RS05060	COG3273	potassium ion transport
BOO69_RS05060	COG0471	metal ion transport
BOO69_RS05075	COG3273	potassium ion transport
BOO69_RS05075	COG0471	metal ion transport
BOO69_RS05080	COG0217	transcriptional regulatory protein
BOO69_RS05105	COG1309	transcriptional regulator
BOO69_RS05110	COG3119	arylsulfatase activity
BOO69_RS05115	COG1012	belongs to the aldehyde dehydrogenase family
BOO69_RS05125	COG1525	nuclease
BOO69_RS05130	COG1396	sequence-specific DNA binding
BOO69_RS05130	COG3800	Transcriptional regulator
BOO69_RS05135	COG2814	Major facilitator Superfamily
BOO69_RS05140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BOO69_RS05170	COG4770	biotin carboxylase activity
BOO69_RS05190	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BOO69_RS05190	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BOO69_RS05205	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BOO69_RS05220	COG0248	Ppx GppA phosphatase
BOO69_RS05225	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BOO69_RS05235	COG0628	permease
BOO69_RS05260	COG2195	Cleaves the N-terminal amino acid of tripeptides
BOO69_RS05270	COG0442	prolyl-tRNA aminoacylation
BOO69_RS05290	COG1136	(ABC) transporter
BOO69_RS05295	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BOO69_RS05320	COG0187	DNA topoisomerase II activity
BOO69_RS05325	COG0662	Cupin 2, conserved barrel domain protein
BOO69_RS05330	COG0596	Alpha beta hydrolase
BOO69_RS05350	COG0534	Mate efflux family protein
BOO69_RS05375	COG1846	Transcriptional regulator
BOO69_RS05390	COG0346	lactoylglutathione lyase activity
BOO69_RS05405	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BOO69_RS05420	COG1278	Cold shock
BOO69_RS05425	COG1393	Belongs to the ArsC family
BOO69_RS05440	COG3220	belongs to the UPF0276 family
BOO69_RS05450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BOO69_RS05475	COG0640	Transcriptional regulator
BOO69_RS05510	COG3243	poly(R)-hydroxyalkanoic acid synthase
BOO69_RS05525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BOO69_RS05530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOO69_RS05535	COG0174	glutamine synthetase
BOO69_RS05540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BOO69_RS05540	COG0519	Catalyzes the synthesis of GMP from XMP
BOO69_RS05545	COG0174	glutamine synthetase
BOO69_RS05550	COG4160	amino acid transport
BOO69_RS05555	COG4215	(ABC) transporter
BOO69_RS05600	COG0504	CTP synthase activity
BOO69_RS05630	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BOO69_RS05665	COG0546	phosphoglycolate phosphatase activity
BOO69_RS05680	COG5001	Diguanylate cyclase
BOO69_RS05680	COG3447	MASE1 domain protein
BOO69_RS05680	COG5002	protein histidine kinase activity
BOO69_RS05715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOO69_RS05740	COG0297	glycogen (starch) synthase activity
BOO69_RS05740	COG0438	transferase activity, transferring glycosyl groups
BOO69_RS05755	COG0489	protein tyrosine kinase activity
BOO69_RS05755	COG3206	protein involved in exopolysaccharide biosynthesis
BOO69_RS05760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BOO69_RS05770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BOO69_RS05805	COG1741	Belongs to the pirin family
BOO69_RS05820	COG1278	Cold shock
BOO69_RS05825	COG1760	l-serine dehydratase
BOO69_RS05830	COG0625	glutathione transferase activity
BOO69_RS05835	COG1755	Isoprenylcysteine carboxyl methyltransferase
BOO69_RS05840	COG3424	synthase
BOO69_RS05845	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BOO69_RS05855	COG0330	HflC and HflK could
BOO69_RS05860	COG0330	HflC and HflK could
BOO69_RS05900	COG0151	Belongs to the GarS family
BOO69_RS05905	COG1570	exodeoxyribonuclease VII activity
BOO69_RS05950	COG0552	protein localization to endoplasmic reticulum
BOO69_RS05955	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BOO69_RS05960	COG0625	glutathione transferase activity
BOO69_RS05970	COG1469	GTP cyclohydrolase I activity
BOO69_RS05980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BOO69_RS05995	COG0752	glycyl-tRNA synthetase alpha subunit
BOO69_RS06010	COG0751	glycine-tRNA ligase activity
BOO69_RS06025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BOO69_RS06030	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BOO69_RS06035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BOO69_RS06045	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BOO69_RS06055	COG1522	sequence-specific DNA binding
BOO69_RS06065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOO69_RS06075	COG1802	Transcriptional regulator
BOO69_RS06085	COG0505	Belongs to the CarA family
BOO69_RS06090	COG1610	YqeY-like protein
BOO69_RS06130	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BOO69_RS06145	COG0210	DNA helicase
BOO69_RS06155	COG0489	protein tyrosine kinase activity
BOO69_RS06165	COG2340	Cysteine-rich secretory protein family
BOO69_RS06170	COG2001	Belongs to the MraZ family
BOO69_RS06175	COG0275	rRNA processing
BOO69_RS06190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BOO69_RS06200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BOO69_RS06205	COG2066	Belongs to the glutaminase family
BOO69_RS06210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BOO69_RS06215	COG2081	HI0933 family
BOO69_RS06220	COG5285	phytanoyl-CoA dioxygenase
BOO69_RS06230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BOO69_RS06235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BOO69_RS06255	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BOO69_RS06260	COG1181	Belongs to the D-alanine--D-alanine ligase family
BOO69_RS06265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BOO69_RS06270	COG0849	cell division
BOO69_RS06275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BOO69_RS06280	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BOO69_RS06285	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BOO69_RS06305	COG3002	Belongs to the UPF0753 family
BOO69_RS06310	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BOO69_RS06325	COG0006	proline dipeptidase activity
BOO69_RS06365	COG0484	heat shock protein binding
BOO69_RS06385	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BOO69_RS06405	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS06410	COG0308	aminopeptidase N
BOO69_RS06425	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BOO69_RS06450	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BOO69_RS06460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS06465	COG0601	transmembrane transport
BOO69_RS06475	COG4172	Belongs to the ABC transporter superfamily
BOO69_RS06480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BOO69_RS06485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOO69_RS06490	COG1473	amidohydrolase
BOO69_RS06495	COG1473	amidohydrolase
BOO69_RS06500	COG0438	transferase activity, transferring glycosyl groups
BOO69_RS06505	COG1519	Transferase
BOO69_RS06510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BOO69_RS06535	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BOO69_RS06540	COG0546	phosphoglycolate phosphatase activity
BOO69_RS06555	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS06570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BOO69_RS06605	COG1086	Polysaccharide biosynthesis protein
BOO69_RS06615	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOO69_RS06620	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOO69_RS06625	COG0649	NAD binding
BOO69_RS06635	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BOO69_RS06635	COG3743	rRNA binding
BOO69_RS06680	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BOO69_RS06685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOO69_RS06700	COG0713	ATP synthesis coupled electron transport
BOO69_RS06715	COG1007	ATP synthesis coupled electron transport
BOO69_RS06725	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BOO69_RS06740	COG0513	Belongs to the DEAD box helicase family
BOO69_RS06750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BOO69_RS06765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BOO69_RS06785	COG0305	Participates in initiation and elongation during chromosome replication
BOO69_RS06790	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BOO69_RS06795	COG0418	dihydroorotase activity
BOO69_RS06830	COG0542	response to heat
BOO69_RS06840	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BOO69_RS06860	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BOO69_RS06865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BOO69_RS06870	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BOO69_RS06885	COG1138	Cytochrome C-type biogenesis protein
BOO69_RS06890	COG3088	subunit of a heme lyase
BOO69_RS06895	COG1024	Enoyl-CoA hydratase
BOO69_RS06910	COG0372	Belongs to the citrate synthase family
BOO69_RS06915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BOO69_RS06925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BOO69_RS06935	COG0315	cyclic pyranopterin monophosphate synthase activity
BOO69_RS06940	COG0134	indole-3-glycerol-phosphate synthase activity
BOO69_RS06945	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BOO69_RS06950	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BOO69_RS06970	COG2354	Protein conserved in bacteria
BOO69_RS06975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BOO69_RS06995	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BOO69_RS07005	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BOO69_RS07030	COG2885	chlorophyll binding
BOO69_RS07035	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BOO69_RS07055	COG0175	sulfate reduction
BOO69_RS07060	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BOO69_RS07070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BOO69_RS07070	COG1648	precorrin-2 dehydrogenase activity
BOO69_RS07075	COG1522	sequence-specific DNA binding
BOO69_RS07080	COG2124	cytochrome p450
BOO69_RS07095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BOO69_RS07100	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BOO69_RS07105	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BOO69_RS07110	COG0149	triose-phosphate isomerase activity
BOO69_RS07125	COG2151	metal-sulfur cluster biosynthetic enzyme
BOO69_RS07130	COG4067	protein conserved in archaea
BOO69_RS07130	COG0189	ligase activity
BOO69_RS07150	COG0343	queuine tRNA-ribosyltransferase activity
BOO69_RS07155	COG1902	pentaerythritol trinitrate reductase activity
BOO69_RS07160	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BOO69_RS07185	COG0406	alpha-ribazole phosphatase activity
BOO69_RS07200	COG3920	Histidine kinase
BOO69_RS07210	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BOO69_RS07220	COG1910	domain protein
BOO69_RS07235	COG0492	ferredoxin-NADP+ reductase activity
BOO69_RS07240	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BOO69_RS07245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BOO69_RS07260	COG2890	protein-(glutamine-N5) methyltransferase activity
BOO69_RS07265	COG4638	Rieske (2fe-2S)
BOO69_RS07270	COG3842	ATPase activity
BOO69_RS07275	COG1177	transmembrane transport
BOO69_RS07280	COG1176	ABC-type spermidine putrescine transport system, permease component I
BOO69_RS07285	COG4638	Rieske (2fe-2S)
BOO69_RS07290	COG0625	glutathione transferase activity
BOO69_RS07295	COG2249	NAD(P)H dehydrogenase (quinone) activity
BOO69_RS07300	COG1733	regulation of RNA biosynthetic process
BOO69_RS07325	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BOO69_RS07380	COG0667	Aldo Keto reductase
BOO69_RS07440	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BOO69_RS07445	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BOO69_RS07450	COG0251	oxidation-reduction process
BOO69_RS07460	COG2166	iron-sulfur cluster assembly
BOO69_RS07465	COG1238	metal cluster binding
BOO69_RS07475	COG0393	Putative heavy-metal-binding
BOO69_RS07485	COG5012	cobalamin binding
BOO69_RS07495	COG0646	methionine synthase
BOO69_RS07495	COG1410	methionine synthase
BOO69_RS07510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BOO69_RS07515	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BOO69_RS07525	COG0047	phosphoribosylformylglycinamidine synthase activity
BOO69_RS07535	COG2204	response regulator
BOO69_RS07545	COG1530	ribonuclease E activity
BOO69_RS07550	COG0425	Belongs to the sulfur carrier protein TusA family
BOO69_RS07555	COG0785	Cytochrome C biogenesis protein
BOO69_RS07570	COG3588	fructose-bisphosphate aldolase
BOO69_RS07590	COG0114	fumarate hydratase activity
BOO69_RS07600	COG2059	Chromate
BOO69_RS07605	COG2205	protein histidine kinase activity
BOO69_RS07605	COG0784	Response regulator, receiver
BOO69_RS07625	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BOO69_RS07635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BOO69_RS07645	COG1309	transcriptional regulator
BOO69_RS07650	COG2326	polyphosphate kinase activity
BOO69_RS07655	COG0596	Alpha beta hydrolase
BOO69_RS07660	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BOO69_RS07680	COG0519	Catalyzes the synthesis of GMP from XMP
BOO69_RS07680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BOO69_RS07705	COG2010	Cytochrome c
BOO69_RS07720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BOO69_RS07725	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BOO69_RS07730	COG2867	negative regulation of translational initiation
BOO69_RS07740	COG0004	ammonium transporteR
BOO69_RS07755	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BOO69_RS07755	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BOO69_RS07760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BOO69_RS07765	COG3852	Histidine kinase
BOO69_RS07770	COG2204	response regulator
BOO69_RS07775	COG5000	phosphorelay sensor kinase activity
BOO69_RS07780	COG2204	response regulator
BOO69_RS07790	COG0569	domain protein
BOO69_RS07795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BOO69_RS07800	COG1923	regulation of RNA biosynthetic process
BOO69_RS07805	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BOO69_RS07815	COG1187	pseudouridine synthase activity
BOO69_RS07825	COG2084	Dehydrogenase
BOO69_RS07840	COG5002	protein histidine kinase activity
BOO69_RS07855	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BOO69_RS07895	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS07910	COG2313	pseudouridylate synthase activity
BOO69_RS07930	COG0352	thiamine-phosphate diphosphorylase activity
BOO69_RS07940	COG1612	heme a metabolic process
BOO69_RS07945	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BOO69_RS07955	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BOO69_RS07960	COG5425	PFAM Usg family protein
BOO69_RS07980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BOO69_RS07990	COG0166	Belongs to the GPI family
BOO69_RS08005	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS08020	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BOO69_RS08050	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BOO69_RS08055	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BOO69_RS08075	COG1217	gtp-binding protein TYPA
BOO69_RS08080	COG2076	Multidrug Resistance protein
BOO69_RS08085	COG1522	sequence-specific DNA binding
BOO69_RS08095	COG0121	glutamine amidotransferase
BOO69_RS08105	COG0538	isocitrate dehydrogenase activity
BOO69_RS08120	COG2945	thiolester hydrolase activity
BOO69_RS08130	COG1104	cysteine desulfurase activity
BOO69_RS08135	COG0719	Fe-S assembly protein
BOO69_RS08140	COG0275	rRNA processing
BOO69_RS08145	COG0396	ATPase activity
BOO69_RS08150	COG0719	Fe-S assembly protein
BOO69_RS08165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BOO69_RS08270	COG4695	Portal protein
BOO69_RS08400	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BOO69_RS08430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BOO69_RS08480	COG0683	leucine binding
BOO69_RS08485	COG2197	response regulator
BOO69_RS08490	COG0642	Histidine kinase
BOO69_RS08500	COG1183	phosphatidylcholine synthase activity
BOO69_RS08505	COG0688	phosphatidylethanolamine metabolic process
BOO69_RS08515	COG2194	sulfuric ester hydrolase activity
BOO69_RS08525	COG2989	Protein conserved in bacteria
BOO69_RS08530	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BOO69_RS08535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BOO69_RS08550	COG0433	COG0433 Predicted ATPase
BOO69_RS08585	COG2133	pyrroloquinoline quinone binding
BOO69_RS08595	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BOO69_RS08605	COG1561	YicC-like family, N-terminal region
BOO69_RS08610	COG0194	GDP metabolic process
BOO69_RS08620	COG5002	protein histidine kinase activity
BOO69_RS08640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BOO69_RS08650	COG0745	RESPONSE REGULATOR receiver
BOO69_RS08655	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BOO69_RS08660	COG2771	luxR family
BOO69_RS08665	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BOO69_RS08670	COG0052	Belongs to the universal ribosomal protein uS2 family
BOO69_RS08700	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BOO69_RS08705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BOO69_RS08710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BOO69_RS08730	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BOO69_RS08775	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BOO69_RS08780	COG1733	regulation of RNA biosynthetic process
BOO69_RS08785	COG5507	3-demethylubiquinone-9 3-methyltransferase
BOO69_RS08790	COG0248	Ppx GppA phosphatase
BOO69_RS08805	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BOO69_RS08820	COG0643	Histidine kinase
BOO69_RS08820	COG0784	Response regulator, receiver
BOO69_RS08820	COG2198	Histidine kinase
BOO69_RS08830	COG0835	chemotaxis
BOO69_RS08835	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BOO69_RS08840	COG0745	RESPONSE REGULATOR receiver
BOO69_RS08855	COG2201	protein-glutamate methylesterase activity
BOO69_RS08870	COG0784	Response regulator, receiver
BOO69_RS08870	COG2198	Histidine kinase
BOO69_RS08870	COG2205	protein histidine kinase activity
BOO69_RS08910	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BOO69_RS08915	COG1846	Transcriptional regulator
BOO69_RS08930	COG1129	ABC transporter
BOO69_RS08985	COG2308	Evidence 4 Homologs of previously reported genes of
BOO69_RS08990	COG0655	NAD(P)H dehydrogenase (quinone) activity
BOO69_RS09060	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOO69_RS09060	COG1902	pentaerythritol trinitrate reductase activity
BOO69_RS09070	COG4999	Histidine kinase
BOO69_RS09070	COG3850	Histidine kinase
BOO69_RS09070	COG2205	protein histidine kinase activity
BOO69_RS09070	COG3437	response regulator, receiver
BOO69_RS09080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BOO69_RS09085	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BOO69_RS09085	COG3264	Mechanosensitive ion channel
BOO69_RS09095	COG0494	nUDIX hydrolase
BOO69_RS09105	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BOO69_RS09110	COG0415	Belongs to the DNA photolyase family
BOO69_RS09115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BOO69_RS09120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BOO69_RS09125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BOO69_RS09130	COG0537	adenosine 5'-monophosphoramidase activity
BOO69_RS09140	COG0604	alcohol dehydrogenase
BOO69_RS09165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOO69_RS09190	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BOO69_RS09195	COG2226	methyltransferase
BOO69_RS09200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BOO69_RS09205	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BOO69_RS09220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BOO69_RS09225	COG0745	RESPONSE REGULATOR receiver
BOO69_RS09235	COG0482	sulfurtransferase activity
BOO69_RS09240	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BOO69_RS09245	COG3494	Protein of unknown function (DUF1009)
BOO69_RS09250	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BOO69_RS09255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BOO69_RS09265	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BOO69_RS09270	COG0750	zinc metalloprotease
BOO69_RS09275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BOO69_RS09285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BOO69_RS09290	COG0233	cytoplasmic translational termination
BOO69_RS09295	COG3920	Histidine kinase
BOO69_RS09300	COG0528	UMP kinase activity
BOO69_RS09305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BOO69_RS09315	COG0601	transmembrane transport
BOO69_RS09320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS09335	COG0741	lytic transglycosylase activity
BOO69_RS09340	COG0629	single-stranded DNA binding
BOO69_RS09345	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BOO69_RS09350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BOO69_RS09360	COG4974	Belongs to the 'phage' integrase family
BOO69_RS09370	COG1183	phosphatidylcholine synthase activity
BOO69_RS09395	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BOO69_RS09415	COG1238	metal cluster binding
BOO69_RS09420	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BOO69_RS09430	COG0010	Belongs to the arginase family
BOO69_RS09435	COG2423	ornithine cyclodeaminase activity
BOO69_RS09440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOO69_RS09450	COG0542	response to heat
BOO69_RS09475	COG1764	response to oxidative stress
BOO69_RS09485	COG2124	cytochrome p450
BOO69_RS09500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BOO69_RS09515	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BOO69_RS09660	COG4373	Mu-like prophage FluMu protein gp28
BOO69_RS09680	COG4383	Mu-like prophage protein gp29
BOO69_RS09700	COG4397	Mu-like prophage major head subunit gpT
BOO69_RS09795	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BOO69_RS09800	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BOO69_RS09810	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BOO69_RS09815	COG0028	Belongs to the TPP enzyme family
BOO69_RS09845	COG0154	amidase activity
BOO69_RS09850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BOO69_RS09855	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BOO69_RS09865	COG0436	Aminotransferase
BOO69_RS09880	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BOO69_RS09890	COG0156	8-amino-7-oxononanoate synthase activity
BOO69_RS09895	COG2814	Major facilitator Superfamily
BOO69_RS09935	COG1741	Belongs to the pirin family
BOO69_RS09950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BOO69_RS09955	COG0830	nickel cation binding
BOO69_RS09960	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BOO69_RS09965	COG0804	urea catabolic process
BOO69_RS09970	COG0832	Belongs to the urease beta subunit family
BOO69_RS09980	COG0831	urea catabolic process
BOO69_RS09985	COG0829	nickel cation binding
BOO69_RS10000	COG0105	UTP biosynthetic process
BOO69_RS10005	COG0488	(ABC) transporter
BOO69_RS10010	COG2095	MarC family integral membrane protein
BOO69_RS10030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BOO69_RS10045	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BOO69_RS10050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BOO69_RS10055	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BOO69_RS10060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BOO69_RS10075	COG2890	protein-(glutamine-N5) methyltransferase activity
BOO69_RS10080	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BOO69_RS10100	COG0010	Belongs to the arginase family
BOO69_RS10105	COG1473	amidohydrolase
BOO69_RS10110	COG3956	TIGRFAM MazG family protein
BOO69_RS10125	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BOO69_RS10140	COG0513	Belongs to the DEAD box helicase family
BOO69_RS10165	COG0148	phosphopyruvate hydratase activity
BOO69_RS10185	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BOO69_RS10190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BOO69_RS10215	COG0488	(ABC) transporter
BOO69_RS10235	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BOO69_RS10240	COG0416	fatty acid biosynthetic process
BOO69_RS10245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BOO69_RS10250	COG0776	regulation of translation
BOO69_RS10265	COG0717	Belongs to the dCTP deaminase family
BOO69_RS10275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BOO69_RS10280	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BOO69_RS10285	COG1472	Belongs to the glycosyl hydrolase 3 family
BOO69_RS10295	COG0018	arginyl-trna synthetase
BOO69_RS10300	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BOO69_RS10305	COG0316	Belongs to the HesB IscA family
BOO69_RS10335	COG2814	Major facilitator Superfamily
BOO69_RS10355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BOO69_RS10360	COG0215	cysteine-tRNA ligase activity
BOO69_RS10390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BOO69_RS10405	COG1278	Cold shock
BOO69_RS10410	COG0259	pyridoxamine-phosphate oxidase activity
BOO69_RS10415	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BOO69_RS10420	COG1280	lysine exporter protein (LysE YggA)
BOO69_RS10425	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BOO69_RS10440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BOO69_RS10460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BOO69_RS10485	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS10510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BOO69_RS10525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BOO69_RS10535	COG2814	Major facilitator Superfamily
BOO69_RS10540	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BOO69_RS10550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BOO69_RS10555	COG2833	Protein of unknown function (DUF455)
BOO69_RS10560	COG0739	heme binding
BOO69_RS10580	COG0126	phosphoglycerate kinase activity
BOO69_RS10585	COG0300	oxidoreductase activity
BOO69_RS10590	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BOO69_RS10595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BOO69_RS10600	COG0022	dehydrogenase e1 component
BOO69_RS10600	COG0508	dehydrogenase complex catalyzes the overall conversion of
BOO69_RS10610	COG0508	dehydrogenase complex catalyzes the overall conversion of
BOO69_RS10695	COG4695	Portal protein
BOO69_RS10710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BOO69_RS10715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BOO69_RS10730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BOO69_RS10745	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BOO69_RS10750	COG3038	cytochrome b561
BOO69_RS10755	COG2353	YceI-like domain
BOO69_RS10765	COG0360	Binds together with S18 to 16S ribosomal RNA
BOO69_RS10770	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BOO69_RS10775	COG0359	binds to the 23S rRNA
BOO69_RS10780	COG0739	heme binding
BOO69_RS10780	COG0741	lytic transglycosylase activity
BOO69_RS10780	COG1196	nuclear chromosome segregation
BOO69_RS10800	COG0544	peptidyl-prolyl cis-trans isomerase activity
BOO69_RS10810	COG3750	Belongs to the UPF0335 family
BOO69_RS10830	COG5002	protein histidine kinase activity
BOO69_RS10840	COG0745	RESPONSE REGULATOR receiver
BOO69_RS10845	COG1396	sequence-specific DNA binding
BOO69_RS10845	COG3800	Transcriptional regulator
BOO69_RS10870	COG0410	ABC transporter
BOO69_RS10875	COG2032	superoxide dismutase activity
BOO69_RS10885	COG0439	Biotin carboxylase
BOO69_RS10890	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BOO69_RS10915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BOO69_RS10920	COG0740	serine-type endopeptidase activity
BOO69_RS10950	COG3483	tryptophan 2,3-dioxygenase activity
BOO69_RS10965	COG1024	Enoyl-CoA hydratase
BOO69_RS10975	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS11005	COG0028	Belongs to the TPP enzyme family
BOO69_RS11025	COG1921	L-seryl-tRNASec selenium transferase activity
BOO69_RS11055	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS11070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BOO69_RS11080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BOO69_RS11080	COG0519	Catalyzes the synthesis of GMP from XMP
BOO69_RS11085	COG0174	glutamine synthetase
BOO69_RS11110	COG1012	belongs to the aldehyde dehydrogenase family
BOO69_RS11115	COG5441	Belongs to the UPF0261 family
BOO69_RS11140	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BOO69_RS11155	COG4221	oxidoreductase activity
BOO69_RS11160	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BOO69_RS11165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BOO69_RS11185	COG0805	protein transport
BOO69_RS11190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BOO69_RS11195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BOO69_RS11215	COG3842	ATPase activity
BOO69_RS11220	COG4335	DNA alkylation repair
BOO69_RS11230	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS11250	COG3448	diguanylate cyclase activity
BOO69_RS11250	COG4175	Glycine betaine
BOO69_RS11275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BOO69_RS11290	COG1686	Belongs to the peptidase S11 family
BOO69_RS11295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BOO69_RS11310	COG0084	hydrolase, TatD family'
BOO69_RS11315	COG1234	tRNA 3'-trailer cleavage
BOO69_RS11325	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS11330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOO69_RS11335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOO69_RS11340	COG1609	Transcriptional regulator
BOO69_RS11350	COG0747	negative chemotaxis
BOO69_RS11355	COG0601	transmembrane transport
BOO69_RS11360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS11365	COG0444	Belongs to the ABC transporter superfamily
BOO69_RS11370	COG4608	Belongs to the ABC transporter superfamily
BOO69_RS11380	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS11410	COG1024	Enoyl-CoA hydratase
BOO69_RS11415	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS11420	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS11425	COG0544	peptidyl-prolyl cis-trans isomerase activity
BOO69_RS11435	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BOO69_RS11470	COG0006	proline dipeptidase activity
BOO69_RS11485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BOO69_RS11515	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS11520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BOO69_RS11530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BOO69_RS11535	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BOO69_RS11540	COG4133	protoheme IX ABC transporter activity
BOO69_RS11545	COG3737	Protein of unknown function (DUF498/DUF598)
BOO69_RS11555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BOO69_RS11560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BOO69_RS11565	COG1862	Preprotein translocase
BOO69_RS11575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BOO69_RS11585	COG1160	GTP binding
BOO69_RS11605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOO69_RS11620	COG5265	(ABC) transporter
BOO69_RS11640	COG3547	Transposase (IS116 IS110 IS902 family)
BOO69_RS11660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BOO69_RS11660	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOO69_RS11675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOO69_RS11680	COG4235	cytochrome complex assembly
BOO69_RS11685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BOO69_RS11705	COG0730	response to heat
BOO69_RS11710	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BOO69_RS11715	COG0668	transmembrane transport
BOO69_RS11720	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BOO69_RS11730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BOO69_RS11745	COG1228	amidohydrolase
BOO69_RS11750	COG2986	histidine ammonia-lyase
BOO69_RS11760	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BOO69_RS11790	COG1175	transmembrane transport
BOO69_RS11800	COG1609	Transcriptional regulator
BOO69_RS11805	COG3781	membrane
BOO69_RS11820	COG1024	Enoyl-CoA hydratase
BOO69_RS11825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BOO69_RS11865	COG0628	permease
BOO69_RS11870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BOO69_RS11875	COG0569	domain protein
BOO69_RS11880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BOO69_RS11930	COG1136	(ABC) transporter
BOO69_RS11950	COG1120	ATPase activity
BOO69_RS11955	COG0747	negative chemotaxis
BOO69_RS11960	COG0601	transmembrane transport
BOO69_RS11965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS11970	COG4172	Belongs to the ABC transporter superfamily
BOO69_RS12010	COG0321	lipoyl(octanoyl) transferase activity
BOO69_RS12020	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BOO69_RS12030	COG0745	RESPONSE REGULATOR receiver
BOO69_RS12045	COG0131	Imidazoleglycerol-phosphate dehydratase
BOO69_RS12050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BOO69_RS12065	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BOO69_RS12070	COG0107	imidazoleglycerol-phosphate synthase activity
BOO69_RS12075	COG0140	phosphoribosyl-ATP diphosphatase activity
BOO69_RS12080	COG1832	CoA-binding protein
BOO69_RS12090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BOO69_RS12120	COG0475	glutathione-regulated potassium exporter activity
BOO69_RS12120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BOO69_RS12125	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BOO69_RS12130	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BOO69_RS12135	COG1329	Transcriptional regulator
BOO69_RS12140	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BOO69_RS12145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BOO69_RS12175	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BOO69_RS12175	COG1793	dna ligase
BOO69_RS12180	COG0671	phosphoesterase, PA-phosphatase related
BOO69_RS12190	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BOO69_RS12210	COG0564	pseudouridine synthase activity
BOO69_RS12255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BOO69_RS12260	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BOO69_RS12265	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BOO69_RS12265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BOO69_RS12295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BOO69_RS12295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BOO69_RS12300	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BOO69_RS12305	COG4221	oxidoreductase activity
BOO69_RS12310	COG0432	Pfam Uncharacterised protein family UPF0047
BOO69_RS12325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BOO69_RS12330	COG0358	DNA primase activity
BOO69_RS12345	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOO69_RS12345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BOO69_RS12355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOO69_RS12360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BOO69_RS12395	COG1595	DNA-templated transcription, initiation
BOO69_RS12430	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS12435	COG0824	Thioesterase
BOO69_RS12435	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOO69_RS12445	COG3246	L-lysine catabolic process to acetate
BOO69_RS12455	COG0667	Aldo Keto reductase
BOO69_RS12465	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BOO69_RS12470	COG0840	transmembrane signaling receptor activity
BOO69_RS12480	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BOO69_RS12485	COG3178	'Phosphotransferase
BOO69_RS12495	COG0402	S-adenosylhomocysteine deaminase activity
BOO69_RS12535	COG1522	sequence-specific DNA binding
BOO69_RS12560	COG0483	inositol monophosphate 1-phosphatase activity
BOO69_RS12565	COG2130	NADP-dependent
BOO69_RS12570	COG0583	DNA-binding transcription factor activity
BOO69_RS12595	COG0525	valine-tRNA ligase activity
BOO69_RS12605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BOO69_RS12615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BOO69_RS12620	COG1132	(ABC) transporter
BOO69_RS12630	COG0354	folic acid binding
BOO69_RS12635	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BOO69_RS12645	COG1492	cobalamin metabolic process
BOO69_RS12665	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BOO69_RS12750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BOO69_RS12760	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS12775	COG0725	ABC transporter, periplasmic molybdate-binding protein
BOO69_RS12780	COG4149	molybdate abc transporter
BOO69_RS12805	COG1162	GTPase activity
BOO69_RS12810	COG0659	secondary active sulfate transmembrane transporter activity
BOO69_RS12815	COG3443	Belongs to the bacterial solute-binding protein 9 family
BOO69_RS12820	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BOO69_RS12825	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BOO69_RS12830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BOO69_RS12845	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BOO69_RS12870	COG3346	SURF1 family
BOO69_RS12880	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BOO69_RS12890	COG0109	protoheme IX farnesyltransferase activity
BOO69_RS12900	COG0312	modulator of DNA gyrase
BOO69_RS12905	COG0758	DNA mediated transformation
BOO69_RS12910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BOO69_RS12910	COG1754	DNA topoisomerase type I activity
BOO69_RS12925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BOO69_RS12955	COG4964	Belongs to the GSP D family
BOO69_RS13005	COG1201	RNA secondary structure unwinding
BOO69_RS13045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BOO69_RS13050	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BOO69_RS13065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BOO69_RS13070	COG0037	tRNA processing
BOO69_RS13080	COG2885	chlorophyll binding
BOO69_RS13085	COG0823	Involved in the tonB-independent uptake of proteins
BOO69_RS13105	COG0824	Thioesterase
BOO69_RS13115	COG2255	four-way junction helicase activity
BOO69_RS13120	COG0632	four-way junction helicase activity
BOO69_RS13160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BOO69_RS13175	COG1703	isobutyryl-CoA mutase activity
BOO69_RS13180	COG1643	Atp-dependent helicase
BOO69_RS13220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOO69_RS13225	COG0745	RESPONSE REGULATOR receiver
BOO69_RS13235	COG0745	RESPONSE REGULATOR receiver
BOO69_RS13240	COG5002	protein histidine kinase activity
BOO69_RS13265	COG1122	ATPase activity
BOO69_RS13320	COG3547	Transposase (IS116 IS110 IS902 family)
BOO69_RS13340	COG0410	ABC transporter
BOO69_RS13350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOO69_RS13355	COG1522	sequence-specific DNA binding
BOO69_RS13365	COG3386	PFAM SMP-30 Gluconolaconase
BOO69_RS13370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOO69_RS13430	COG0012	GTP binding
BOO69_RS13445	COG0159	tryptophan synthase activity
BOO69_RS13460	COG1304	FMN binding
BOO69_RS13475	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BOO69_RS13485	COG0193	aminoacyl-tRNA hydrolase activity
BOO69_RS13510	COG0133	tryptophan synthase activity
BOO69_RS13520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BOO69_RS13570	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BOO69_RS13580	COG0456	acetyltransferase
BOO69_RS13585	COG1744	ABC transporter substrate-binding protein PnrA-like
BOO69_RS13590	COG3845	ABC transporter
BOO69_RS13595	COG4603	Belongs to the binding-protein-dependent transport system permease family
BOO69_RS13600	COG1079	Belongs to the binding-protein-dependent transport system permease family
BOO69_RS13605	COG0730	response to heat
BOO69_RS13615	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS13620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BOO69_RS13630	COG0604	alcohol dehydrogenase
BOO69_RS13640	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BOO69_RS13640	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BOO69_RS13650	COG0813	purine-nucleoside phosphorylase activity
BOO69_RS13705	COG0039	L-malate dehydrogenase activity
BOO69_RS13725	COG2301	Belongs to the HpcH HpaI aldolase family
BOO69_RS13740	COG2030	dehydratase
BOO69_RS13745	COG0121	glutamine amidotransferase
BOO69_RS13760	COG0045	succinate-CoA ligase (ADP-forming) activity
BOO69_RS13795	COG0567	Dehydrogenase, E1 component
BOO69_RS13800	COG0508	dehydrogenase complex catalyzes the overall conversion of
BOO69_RS13855	COG2884	Cell division ATP-binding protein ftsE
BOO69_RS13870	COG0019	diaminopimelate decarboxylase activity
BOO69_RS13885	COG0165	Argininosuccinate lyase
BOO69_RS13890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BOO69_RS13915	COG0402	S-adenosylhomocysteine deaminase activity
BOO69_RS13920	COG1079	Belongs to the binding-protein-dependent transport system permease family
BOO69_RS13925	COG4603	Belongs to the binding-protein-dependent transport system permease family
BOO69_RS13930	COG3845	ABC transporter
BOO69_RS13940	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BOO69_RS13955	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BOO69_RS13970	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BOO69_RS13975	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BOO69_RS13980	COG0124	histidyl-tRNA synthetase
BOO69_RS14015	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BOO69_RS14025	COG3845	ABC transporter
BOO69_RS14030	COG4603	Belongs to the binding-protein-dependent transport system permease family
BOO69_RS14035	COG1079	Belongs to the binding-protein-dependent transport system permease family
BOO69_RS14090	COG0277	FAD linked oxidase domain protein
BOO69_RS14110	COG1063	alcohol dehydrogenase
BOO69_RS14125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BOO69_RS14180	COG2124	cytochrome p450
BOO69_RS14205	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS14205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOO69_RS14205	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS14205	COG0300	oxidoreductase activity
BOO69_RS14205	COG3321	synthase
BOO69_RS14210	COG2226	methyltransferase
BOO69_RS14255	COG1475	DNA binding
BOO69_RS14280	COG0154	amidase activity
BOO69_RS14305	COG0559	Belongs to the binding-protein-dependent transport system permease family
BOO69_RS14315	COG2909	trisaccharide binding
BOO69_RS14325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BOO69_RS14365	COG4191	Histidine kinase
BOO69_RS14380	COG2358	TRAP transporter, solute receptor (TAXI family
BOO69_RS14405	COG1462	curli production assembly transport component CsgG
BOO69_RS14460	COG0456	acetyltransferase
BOO69_RS14465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BOO69_RS14470	COG1917	Cupin 2, conserved barrel domain protein
BOO69_RS14475	COG0527	aspartate kinase activity
BOO69_RS14495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BOO69_RS14510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOO69_RS14515	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BOO69_RS14520	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BOO69_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS14540	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BOO69_RS14540	COG0028	Belongs to the TPP enzyme family
BOO69_RS14545	COG1846	Transcriptional regulator
BOO69_RS14560	COG0033	Phosphoglucomutase
BOO69_RS14570	COG3842	ATPase activity
BOO69_RS14575	COG1176	ABC-type spermidine putrescine transport system, permease component I
BOO69_RS14580	COG1177	transmembrane transport
BOO69_RS14600	COG1072	(Pantothenic acid kinase))
BOO69_RS14605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BOO69_RS14610	COG0800	Aldolase
BOO69_RS14615	COG0129	dihydroxy-acid dehydratase activity
BOO69_RS14620	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BOO69_RS14625	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BOO69_RS14630	COG3639	organic phosphonate transmembrane transporter activity
BOO69_RS14635	COG3639	organic phosphonate transmembrane transporter activity
BOO69_RS14640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BOO69_RS14650	COG2188	Transcriptional regulator
BOO69_RS14655	COG3624	Phosphonate C-P lyase system protein PhnG
BOO69_RS14660	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BOO69_RS14665	COG3626	phosphonate metabolism
BOO69_RS14675	COG3627	carbon phosphorus lyase activity
BOO69_RS14680	COG4107	phosphonate C-P lyase system protein PhnK
BOO69_RS14685	COG4778	phosphonate C-P lyase system protein PhnL
BOO69_RS14700	COG3454	Phosphonate metabolism
BOO69_RS14705	COG1840	ABC-type Fe3 transport system, periplasmic component
BOO69_RS14770	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS14775	COG1024	Enoyl-CoA hydratase
BOO69_RS14785	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS14790	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS14795	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOO69_RS14795	COG1024	Enoyl-CoA hydratase
BOO69_RS14820	COG0601	transmembrane transport
BOO69_RS14825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS14830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BOO69_RS14835	COG0668	transmembrane transport
BOO69_RS14850	COG0438	transferase activity, transferring glycosyl groups
BOO69_RS14855	COG0588	phosphoglycerate mutase activity
BOO69_RS14880	COG0481	GTPase activity
BOO69_RS14910	COG5328	Belongs to the UPF0262 family
BOO69_RS14915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BOO69_RS14925	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BOO69_RS14945	COG0811	peptide transport
BOO69_RS14965	COG2207	Transcriptional regulator
BOO69_RS14970	COG4774	siderophore transport
BOO69_RS14980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BOO69_RS14985	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BOO69_RS14990	COG1120	ATPase activity
BOO69_RS15000	COG1132	(ABC) transporter
BOO69_RS15010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BOO69_RS15015	COG1116	anion transmembrane transporter activity
BOO69_RS15020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BOO69_RS15040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOO69_RS15050	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOO69_RS15050	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BOO69_RS15060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BOO69_RS15125	COG3842	ATPase activity
BOO69_RS15140	COG1177	transmembrane transport
BOO69_RS15145	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS15160	COG0427	acetyl-CoA hydrolase
BOO69_RS15165	COG3608	succinylglutamate desuccinylase aspartoacylase
BOO69_RS15170	COG0006	proline dipeptidase activity
BOO69_RS15175	COG2423	ornithine cyclodeaminase activity
BOO69_RS15180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BOO69_RS15190	COG0589	response to stress
BOO69_RS15195	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BOO69_RS15200	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BOO69_RS15205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BOO69_RS15210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOO69_RS15215	COG1522	sequence-specific DNA binding
BOO69_RS15220	COG1012	belongs to the aldehyde dehydrogenase family
BOO69_RS15225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BOO69_RS15250	COG0667	Aldo Keto reductase
BOO69_RS15275	COG2951	lytic endotransglycosylase activity
BOO69_RS15295	COG3180	Ammonia monooxygenase
BOO69_RS15325	COG2205	protein histidine kinase activity
BOO69_RS15350	COG0556	nucleotide-excision repair
BOO69_RS15385	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BOO69_RS15415	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BOO69_RS15420	COG1115	amino acid carrier protein
BOO69_RS15435	COG0488	(ABC) transporter
BOO69_RS15440	COG0745	RESPONSE REGULATOR receiver
BOO69_RS15445	COG1376	ErfK ybiS ycfS ynhG family protein
BOO69_RS15455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BOO69_RS15460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BOO69_RS15485	COG1309	transcriptional regulator
BOO69_RS15500	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BOO69_RS15505	COG0493	'glutamate synthase
BOO69_RS15510	COG1278	Cold shock
BOO69_RS15525	COG1136	(ABC) transporter
BOO69_RS15535	COG0483	inositol monophosphate 1-phosphatase activity
BOO69_RS15545	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BOO69_RS15545	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BOO69_RS15550	COG0509	glycine decarboxylation via glycine cleavage system
BOO69_RS15555	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BOO69_RS15570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BOO69_RS15580	COG2070	2-Nitropropane dioxygenase
BOO69_RS15600	COG0655	NAD(P)H dehydrogenase (quinone) activity
BOO69_RS15610	COG3046	protein related to deoxyribodipyrimidine photolyase
BOO69_RS15620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BOO69_RS15630	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BOO69_RS15665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BOO69_RS15695	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BOO69_RS15730	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BOO69_RS15740	COG1686	Belongs to the peptidase S11 family
BOO69_RS15745	COG0583	DNA-binding transcription factor activity
BOO69_RS15750	COG4172	Belongs to the ABC transporter superfamily
BOO69_RS15755	COG4239	(ABC) transporter, permease
BOO69_RS15760	COG4174	ABC transporter (Permease)
BOO69_RS15775	COG0077	Prephenate dehydratase
BOO69_RS15795	COG2816	NAD+ diphosphatase activity
BOO69_RS15805	COG2321	neutral zinc metallopeptidase
BOO69_RS15815	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BOO69_RS15825	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BOO69_RS15855	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS15860	COG0183	Belongs to the thiolase family
BOO69_RS15865	COG1268	BioY protein
BOO69_RS15870	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BOO69_RS15875	COG1122	ATPase activity
BOO69_RS15885	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BOO69_RS15890	COG1522	sequence-specific DNA binding
BOO69_RS15895	COG0686	Belongs to the AlaDH PNT family
BOO69_RS15900	COG1970	mechanosensitive ion channel activity
BOO69_RS15905	COG0625	glutathione transferase activity
BOO69_RS15915	COG0072	phenylalanine-tRNA ligase activity
BOO69_RS15915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BOO69_RS15925	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BOO69_RS15935	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BOO69_RS15940	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BOO69_RS15950	COG0469	pyruvate kinase activity
BOO69_RS15980	COG0768	penicillin binding
BOO69_RS15985	COG0772	Belongs to the SEDS family
BOO69_RS15995	COG0339	signal peptide processing
BOO69_RS16000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BOO69_RS16005	COG0756	dUTP diphosphatase activity
BOO69_RS16010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BOO69_RS16025	COG0406	alpha-ribazole phosphatase activity
BOO69_RS16035	COG0606	chelatase, subunit chli
BOO69_RS16050	COG0792	nuclease activity
BOO69_RS16055	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BOO69_RS16065	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BOO69_RS16080	COG0180	Tryptophanyl-tRNA synthetase
BOO69_RS16105	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BOO69_RS16135	COG0745	RESPONSE REGULATOR receiver
BOO69_RS16140	COG0346	lactoylglutathione lyase activity
BOO69_RS16155	COG0778	Nitroreductase
BOO69_RS16165	COG2514	catechol 2,3-dioxygenase activity
BOO69_RS16210	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BOO69_RS16215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BOO69_RS16220	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BOO69_RS16225	COG0542	response to heat
BOO69_RS16235	COG0284	orotidine-5'-phosphate decarboxylase activity
BOO69_RS16245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BOO69_RS16270	COG0625	glutathione transferase activity
BOO69_RS16275	COG1178	ABC-type Fe3 transport system permease component
BOO69_RS16310	COG0559	Belongs to the binding-protein-dependent transport system permease family
BOO69_RS16335	COG4191	Histidine kinase
BOO69_RS16400	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BOO69_RS16410	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BOO69_RS16415	COG3257	ureidoglycine aminohydrolase activity
BOO69_RS16425	COG2351	hydroxyisourate hydrolase activity
BOO69_RS16430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BOO69_RS16435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BOO69_RS16440	COG1121	(ABC) transporter
BOO69_RS16445	COG0803	Belongs to the bacterial solute-binding protein 9 family
BOO69_RS16450	COG2205	protein histidine kinase activity
BOO69_RS16455	COG0745	RESPONSE REGULATOR receiver
BOO69_RS16470	COG1012	belongs to the aldehyde dehydrogenase family
BOO69_RS16475	COG0612	Peptidase, M16
BOO69_RS16480	COG0612	Peptidase, M16
BOO69_RS16490	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BOO69_RS16495	COG0138	bifunctional purine biosynthesis protein purh
BOO69_RS16525	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BOO69_RS16530	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BOO69_RS16540	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BOO69_RS16555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BOO69_RS16570	COG1185	polyribonucleotide nucleotidyltransferase activity
BOO69_RS16590	COG0564	pseudouridine synthase activity
BOO69_RS16610	COG0450	alkyl hydroperoxide reductase
BOO69_RS16640	COG1280	lysine exporter protein (LysE YggA)
BOO69_RS16655	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BOO69_RS16660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BOO69_RS16670	COG1366	Belongs to the anti-sigma-factor antagonist family
BOO69_RS16680	COG0405	Gamma-glutamyltransferase
BOO69_RS16700	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BOO69_RS16710	COG1674	ftsk spoiiie
BOO69_RS16715	COG0436	Aminotransferase
BOO69_RS16720	COG0154	amidase activity
BOO69_RS16725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOO69_RS16730	COG2835	tetraacyldisaccharide 4'-kinase activity
BOO69_RS16735	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BOO69_RS16750	COG0745	RESPONSE REGULATOR receiver
BOO69_RS16765	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BOO69_RS16780	COG0495	leucyl-tRNA aminoacylation
BOO69_RS16825	COG0300	oxidoreductase activity
BOO69_RS16835	COG0312	modulator of DNA gyrase
BOO69_RS16855	COG1663	tetraacyldisaccharide 4'-kinase activity
BOO69_RS16875	COG1194	a g-specific adenine glycosylase
BOO69_RS16895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BOO69_RS16930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BOO69_RS16940	COG0288	reversible hydration of carbon dioxide
BOO69_RS16950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BOO69_RS16955	COG0791	NLP P60 protein
BOO69_RS16965	COG2050	protein possibly involved in aromatic compounds catabolism
BOO69_RS16990	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BOO69_RS16995	COG1671	Belongs to the UPF0178 family
BOO69_RS17005	COG2423	ornithine cyclodeaminase activity
BOO69_RS17020	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BOO69_RS17030	COG0285	dihydrofolate synthase activity
BOO69_RS17035	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BOO69_RS17045	COG1132	(ABC) transporter
BOO69_RS17060	COG0129	dihydroxy-acid dehydratase activity
BOO69_RS17080	COG0793	Belongs to the peptidase S41A family
BOO69_RS17090	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BOO69_RS17105	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BOO69_RS17105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BOO69_RS17120	COG3622	Belongs to the hyi family
BOO69_RS17130	COG0714	Associated with various cellular activities
BOO69_RS17160	COG4953	penicillin-binding protein 1C
BOO69_RS17165	COG2373	Large extracellular alpha-helical protein
BOO69_RS17170	COG0784	Response regulator, receiver
BOO69_RS17170	COG2205	protein histidine kinase activity
BOO69_RS17170	COG5002	protein histidine kinase activity
BOO69_RS17175	COG3022	response to hydroperoxide
BOO69_RS17185	COG0514	ATP-dependent DNA helicase (RecQ)
BOO69_RS17220	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BOO69_RS17230	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BOO69_RS17250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BOO69_RS17250	COG1648	precorrin-2 dehydrogenase activity
BOO69_RS17255	COG1797	cobyrinic acid a,c-diamide synthase activity
BOO69_RS17260	COG2875	Belongs to the precorrin methyltransferase family
BOO69_RS17275	COG2099	Precorrin-6x reductase
BOO69_RS17340	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS17345	COG1024	Enoyl-CoA hydratase
BOO69_RS17365	COG3842	ATPase activity
BOO69_RS17370	COG1309	transcriptional regulator
BOO69_RS17390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOO69_RS17395	COG0436	Aminotransferase
BOO69_RS17420	COG0583	DNA-binding transcription factor activity
BOO69_RS17430	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BOO69_RS17440	COG2095	MarC family integral membrane protein
BOO69_RS17445	COG1335	isochorismatase
BOO69_RS17450	COG1054	Belongs to the UPF0176 family
BOO69_RS17480	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BOO69_RS17485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOO69_RS17490	COG1177	transmembrane transport
BOO69_RS17495	COG1176	ABC-type spermidine putrescine transport system, permease component I
BOO69_RS17500	COG3842	ATPase activity
BOO69_RS17510	COG1802	Transcriptional regulator
BOO69_RS17520	COG2951	lytic endotransglycosylase activity
BOO69_RS17525	COG2378	regulation of single-species biofilm formation
BOO69_RS17530	COG0557	exoribonuclease II activity
BOO69_RS17540	COG2153	protein acetylation
BOO69_RS17545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BOO69_RS17575	COG2171	N-acyltransferase activity
BOO69_RS17600	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BOO69_RS17620	COG0560	Phosphoserine phosphatase
BOO69_RS17620	COG3830	Belongs to the UPF0237 family
BOO69_RS17625	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BOO69_RS17630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BOO69_RS17645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BOO69_RS17655	COG1063	alcohol dehydrogenase
BOO69_RS17660	COG0156	8-amino-7-oxononanoate synthase activity
BOO69_RS17665	COG1396	sequence-specific DNA binding
BOO69_RS17670	COG0183	Belongs to the thiolase family
BOO69_RS17695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS17715	COG3191	aminopeptidase activity
BOO69_RS17740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOO69_RS17770	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BOO69_RS17800	COG0438	transferase activity, transferring glycosyl groups
BOO69_RS17830	COG0601	transmembrane transport
BOO69_RS17835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS17875	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS17910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BOO69_RS17915	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BOO69_RS17940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BOO69_RS17950	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BOO69_RS17960	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BOO69_RS17965	COG1999	signal sequence binding
BOO69_RS17980	COG0802	atpase or kinase
BOO69_RS17985	COG3178	'Phosphotransferase
BOO69_RS18015	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BOO69_RS18025	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BOO69_RS18055	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BOO69_RS18060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BOO69_RS18065	COG0237	dephospho-CoA kinase activity
BOO69_RS18070	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BOO69_RS18075	COG0424	maF-like protein
BOO69_RS18080	COG1981	membrane
BOO69_RS18085	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BOO69_RS18090	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BOO69_RS18095	COG0445	tRNA wobble uridine modification
BOO69_RS18100	COG0357	Ribosomal RNA small subunit methyltransferase G
BOO69_RS18115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BOO69_RS18120	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BOO69_RS18125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BOO69_RS18130	COG1420	regulation of RNA biosynthetic process
BOO69_RS18135	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BOO69_RS18140	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BOO69_RS18150	COG0280	phosphate acetyltransferase
BOO69_RS18150	COG0281	malic enzyme
BOO69_RS18155	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BOO69_RS18155	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BOO69_RS18160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BOO69_RS18165	COG0583	DNA-binding transcription factor activity
BOO69_RS18170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BOO69_RS18175	COG3485	protocatechuate 3,4-dioxygenase
BOO69_RS18180	COG3485	protocatechuate 3,4-dioxygenase
BOO69_RS18185	COG3246	L-lysine catabolic process to acetate
BOO69_RS18190	COG0436	Aminotransferase
BOO69_RS18225	COG0297	glycogen (starch) synthase activity
BOO69_RS18225	COG0438	transferase activity, transferring glycosyl groups
BOO69_RS18255	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BOO69_RS18265	COG4533	DNA binding
BOO69_RS18270	COG0601	transmembrane transport
BOO69_RS18275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS18280	COG0444	Belongs to the ABC transporter superfamily
BOO69_RS18305	COG0137	argininosuccinate synthase activity
BOO69_RS18310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BOO69_RS18315	COG0300	oxidoreductase activity
BOO69_RS18325	COG0745	RESPONSE REGULATOR receiver
BOO69_RS18330	COG0494	nUDIX hydrolase
BOO69_RS18340	COG0494	nUDIX hydrolase
BOO69_RS18345	COG0617	tRNA 3'-terminal CCA addition
BOO69_RS18350	COG1132	(ABC) transporter
BOO69_RS18355	COG1132	(ABC) transporter
BOO69_RS18360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BOO69_RS18365	COG3034	peptidoglycan biosynthetic process
BOO69_RS18390	COG2226	methyltransferase
BOO69_RS18405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BOO69_RS18415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BOO69_RS18425	COG0747	negative chemotaxis
BOO69_RS18430	COG0779	Required for maturation of 30S ribosomal subunits
BOO69_RS18445	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BOO69_RS18460	COG0494	nUDIX hydrolase
BOO69_RS18465	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BOO69_RS18470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BOO69_RS18475	COG0653	protein targeting
BOO69_RS18490	COG2003	Belongs to the UPF0758 family
BOO69_RS18495	COG0484	heat shock protein binding
BOO69_RS18500	COG0443	Heat shock 70 kDa protein
BOO69_RS18515	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BOO69_RS18555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOO69_RS18560	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BOO69_RS18565	COG1137	ATPase activity
BOO69_RS18580	COG0517	IMP dehydrogenase activity
BOO69_RS18580	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BOO69_RS18585	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BOO69_RS18590	COG3327	negative regulation of DNA-templated transcription, initiation
BOO69_RS18595	COG2030	dehydratase
BOO69_RS18595	COG1012	belongs to the aldehyde dehydrogenase family
BOO69_RS18605	COG2151	metal-sulfur cluster biosynthetic enzyme
BOO69_RS18610	COG3396	Phenylacetate-CoA oxygenase
BOO69_RS18615	COG3460	Phenylacetate-CoA oxygenase
BOO69_RS18620	COG3396	Phenylacetate-CoA oxygenase
BOO69_RS18625	COG0183	Belongs to the thiolase family
BOO69_RS18630	COG0625	glutathione transferase activity
BOO69_RS18640	COG2186	Transcriptional regulator
BOO69_RS18645	COG0747	negative chemotaxis
BOO69_RS18650	COG0601	transmembrane transport
BOO69_RS18655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS18665	COG0402	S-adenosylhomocysteine deaminase activity
BOO69_RS18670	COG0444	Belongs to the ABC transporter superfamily
BOO69_RS18675	COG4608	Belongs to the ABC transporter superfamily
BOO69_RS18700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BOO69_RS18710	COG2267	carboxylic ester hydrolase activity
BOO69_RS18715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BOO69_RS18730	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOO69_RS18740	COG1879	ABC-type sugar transport system periplasmic component
BOO69_RS18745	COG1984	allophanate hydrolase subunit 2
BOO69_RS18760	COG0511	ligase activity, forming carbon-carbon bonds
BOO69_RS18795	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS18800	COG1012	belongs to the aldehyde dehydrogenase family
BOO69_RS18815	COG1802	Transcriptional regulator
BOO69_RS18820	COG0765	amino acid transport
BOO69_RS18825	COG4597	amino acid ABC transporter
BOO69_RS18830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOO69_RS18835	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BOO69_RS18860	COG4993	Dehydrogenase
BOO69_RS18880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BOO69_RS18885	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BOO69_RS18885	COG2010	Cytochrome c
BOO69_RS18900	COG4208	sulfate ABC transporter
BOO69_RS18915	COG3842	ATPase activity
BOO69_RS18930	COG0154	amidase activity
BOO69_RS18940	COG4172	Belongs to the ABC transporter superfamily
BOO69_RS18945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS18955	COG4533	DNA binding
BOO69_RS18960	COG1473	amidohydrolase
BOO69_RS18965	COG0657	acetylesterase activity
BOO69_RS18975	COG1176	ABC-type spermidine putrescine transport system, permease component I
BOO69_RS18980	COG3842	ATPase activity
BOO69_RS18990	COG3842	ATPase activity
BOO69_RS18995	COG0395	ABC-type sugar transport system, permease component
BOO69_RS19000	COG1175	transmembrane transport
BOO69_RS19020	COG1283	sodium-dependent phosphate transmembrane transporter activity
BOO69_RS19030	COG0601	transmembrane transport
BOO69_RS19035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS19040	COG0444	Belongs to the ABC transporter superfamily
BOO69_RS19045	COG4608	Belongs to the ABC transporter superfamily
BOO69_RS19050	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BOO69_RS19060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOO69_RS19065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOO69_RS19075	COG1192	Involved in chromosome partitioning
BOO69_RS19080	COG1475	DNA binding
BOO69_RS19095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BOO69_RS19135	COG2268	Band 7 protein
BOO69_RS19145	COG0559	Belongs to the binding-protein-dependent transport system permease family
BOO69_RS19165	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS19170	COG0697	spore germination
BOO69_RS19175	COG0583	DNA-binding transcription factor activity
BOO69_RS19185	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS19190	COG2080	2 iron, 2 sulfur cluster binding
BOO69_RS19195	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BOO69_RS19200	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BOO69_RS19215	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BOO69_RS19220	COG0181	hydroxymethylbilane synthase activity
BOO69_RS19225	COG0156	8-amino-7-oxononanoate synthase activity
BOO69_RS19235	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BOO69_RS19270	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BOO69_RS19275	COG1429	ligase activity, forming nitrogen-metal bonds
BOO69_RS19280	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BOO69_RS19285	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BOO69_RS19310	COG1215	transferase activity, transferring glycosyl groups
BOO69_RS19315	COG1454	alcohol dehydrogenase
BOO69_RS19320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BOO69_RS19340	COG0395	ABC-type sugar transport system, permease component
BOO69_RS19345	COG1175	transmembrane transport
BOO69_RS19350	COG3842	ATPase activity
BOO69_RS19355	COG3842	ATPase activity
BOO69_RS19385	COG0179	Fumarylacetoacetate (FAA) hydrolase
BOO69_RS19390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BOO69_RS19435	COG3474	cytochrome
BOO69_RS19440	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BOO69_RS19445	COG2211	Major facilitator Superfamily
BOO69_RS19450	COG0644	oxidoreductase
BOO69_RS19460	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BOO69_RS19495	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BOO69_RS19500	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BOO69_RS19505	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BOO69_RS19510	COG1063	alcohol dehydrogenase
BOO69_RS19515	COG0500	methyltransferase
BOO69_RS19520	COG0142	geranyltranstransferase activity
BOO69_RS19530	COG5621	secreted hydrolase
BOO69_RS19535	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BOO69_RS19540	COG1562	ergosterol biosynthetic process
BOO69_RS19545	COG1233	COG1233 Phytoene dehydrogenase and related
BOO69_RS19555	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
BOO69_RS19560	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
BOO69_RS19570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BOO69_RS19575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BOO69_RS19600	COG0785	Cytochrome C biogenesis protein
BOO69_RS19735	COG1196	nuclear chromosome segregation
BOO69_RS19735	COG0741	lytic transglycosylase activity
BOO69_RS19735	COG0739	heme binding
BOO69_RS19755	COG0739	heme binding
BOO69_RS19755	COG0741	lytic transglycosylase activity
BOO69_RS19755	COG1196	nuclear chromosome segregation
BOO69_RS19775	COG2948	multi-organism process
BOO69_RS19780	COG4962	Type ii secretion system protein e
BOO69_RS19845	COG3077	Addiction module antitoxin, RelB DinJ family
BOO69_RS19865	COG3547	Transposase (IS116 IS110 IS902 family)
BOO69_RS19880	COG0583	DNA-binding transcription factor activity
BOO69_RS19910	COG1192	Involved in chromosome partitioning
BOO69_RS19915	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BOO69_RS19970	COG2132	Multicopper oxidase
BOO69_RS19975	COG1321	iron dependent repressor
BOO69_RS20000	COG3034	peptidoglycan biosynthetic process
BOO69_RS20010	COG2366	antibiotic biosynthetic process
BOO69_RS20015	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BOO69_RS20040	COG1999	signal sequence binding
BOO69_RS20050	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BOO69_RS20050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BOO69_RS20060	COG1999	signal sequence binding
BOO69_RS20065	COG0789	Transcriptional regulator
BOO69_RS20110	COG4227	nucleotidyltransferase activity
BOO69_RS20130	COG3505	Type IV secretory pathway VirD4
BOO69_RS20155	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BOO69_RS20205	COG1192	Involved in chromosome partitioning
BOO69_RS20240	COG2226	methyltransferase
BOO69_RS20275	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BOO69_RS20275	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BOO69_RS20280	COG1024	Enoyl-CoA hydratase
BOO69_RS20285	COG0183	Belongs to the thiolase family
BOO69_RS20290	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS20300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOO69_RS20325	COG1022	Amp-dependent synthetase and ligase
BOO69_RS20365	COG4962	Type ii secretion system protein e
BOO69_RS20370	COG2948	multi-organism process
BOO69_RS20410	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS20465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BOO69_RS20470	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS20475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BOO69_RS20490	COG0747	negative chemotaxis
BOO69_RS20495	COG4608	Belongs to the ABC transporter superfamily
BOO69_RS20500	COG0444	Belongs to the ABC transporter superfamily
BOO69_RS20505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOO69_RS20510	COG0601	transmembrane transport
BOO69_RS20530	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BOO69_RS20540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BOO69_RS20550	COG1414	Transcriptional regulator
BOO69_RS20555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BOO69_RS20565	COG0006	proline dipeptidase activity
BOO69_RS20585	COG0747	negative chemotaxis
BOO69_RS20605	COG0444	Belongs to the ABC transporter superfamily
BOO69_RS20610	COG4608	Belongs to the ABC transporter superfamily
BOO69_RS20615	COG0408	coproporphyrinogen oxidase activity
BOO69_RS20650	COG1846	Transcriptional regulator
BOO69_RS20685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BOO69_RS20710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOO69_RS20740	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BOO69_RS20750	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOO69_RS20755	COG1129	ABC transporter
BOO69_RS20760	COG0673	inositol 2-dehydrogenase activity
BOO69_RS20770	COG2115	Belongs to the xylose isomerase family
BOO69_RS20775	COG1609	Transcriptional regulator
BOO69_RS20785	COG0735	belongs to the Fur family
BOO69_RS20790	COG1121	(ABC) transporter
BOO69_RS20795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BOO69_RS20810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BOO69_RS20820	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BOO69_RS20830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BOO69_RS20865	COG1022	Amp-dependent synthetase and ligase
BOO69_RS20880	COG1024	Enoyl-CoA hydratase
BOO69_RS20890	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS20895	COG1129	ABC transporter
BOO69_RS20915	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOO69_RS20965	COG1024	Enoyl-CoA hydratase
BOO69_RS20970	COG2030	dehydratase
BOO69_RS20970	COG1012	belongs to the aldehyde dehydrogenase family
BOO69_RS20980	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS20985	COG1024	Enoyl-CoA hydratase
BOO69_RS20995	COG0439	Biotin carboxylase
BOO69_RS21005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BOO69_RS21015	COG1309	transcriptional regulator
BOO69_RS21020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BOO69_RS21025	COG3568	Endonuclease Exonuclease Phosphatase
BOO69_RS21055	COG4529	Protein conserved in bacteria
BOO69_RS21075	COG0438	transferase activity, transferring glycosyl groups
BOO69_RS21080	COG3551	Protein conserved in bacteria
BOO69_RS21085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BOO69_RS21105	COG0402	S-adenosylhomocysteine deaminase activity
BOO69_RS21110	COG1475	DNA binding
BOO69_RS21115	COG1192	Involved in chromosome partitioning
BOO69_RS21120	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BOO69_RS21125	COG3609	addiction module antidote protein, CC2985 family
BOO69_RS21150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOO69_RS21155	COG0842	Transport permease protein
BOO69_RS21155	COG1129	ABC transporter
BOO69_RS21175	COG1846	Transcriptional regulator
BOO69_RS21180	COG1566	PFAM secretion protein HlyD family protein
BOO69_RS21185	COG2814	Major facilitator Superfamily
BOO69_RS21200	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BOO69_RS21200	COG2010	Cytochrome c
BOO69_RS21220	COG0702	epimerase
BOO69_RS21230	COG3384	dioxygenase
BOO69_RS21240	COG1733	regulation of RNA biosynthetic process
BOO69_RS21245	COG1309	transcriptional regulator
BOO69_RS21275	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS21315	COG1024	Enoyl-CoA hydratase
BOO69_RS21320	COG1024	Enoyl-CoA hydratase
BOO69_RS21340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOO69_RS21360	COG2030	dehydratase
BOO69_RS21365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOO69_RS21380	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21385	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21405	COG1024	Enoyl-CoA hydratase
BOO69_RS21410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOO69_RS21415	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21420	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21445	COG0183	Belongs to the thiolase family
BOO69_RS21475	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21480	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21495	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21515	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BOO69_RS21525	COG2358	TRAP transporter, solute receptor (TAXI family
BOO69_RS21530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BOO69_RS21540	COG0183	Belongs to the thiolase family
BOO69_RS21545	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOO69_RS21585	COG2433	Pfam Transposase IS66
BOO69_RS21590	COG3436	PFAM IS66 Orf2 family protein
BOO69_RS21620	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21625	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS21630	COG1012	belongs to the aldehyde dehydrogenase family
BOO69_RS21630	COG2030	dehydratase
BOO69_RS21650	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOO69_RS21715	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21725	COG1024	Enoyl-CoA hydratase
BOO69_RS21730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOO69_RS21770	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BOO69_RS21775	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21785	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS21800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BOO69_RS21805	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BOO69_RS21815	COG1024	Enoyl-CoA hydratase
BOO69_RS21820	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21825	COG1902	pentaerythritol trinitrate reductase activity
BOO69_RS21825	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOO69_RS21830	COG0318	PFAM AMP-dependent synthetase and ligase
BOO69_RS21835	COG0625	glutathione transferase activity
BOO69_RS21840	COG2259	Doxx family
BOO69_RS21880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BOO69_RS21885	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS21890	COG1309	transcriptional regulator
BOO69_RS21910	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS21915	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21920	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21925	COG1024	Enoyl-CoA hydratase
BOO69_RS21940	COG5016	pyruvate
BOO69_RS21940	COG0511	ligase activity, forming carbon-carbon bonds
BOO69_RS21960	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS21965	COG1309	transcriptional regulator
BOO69_RS21970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BOO69_RS21975	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BOO69_RS21985	COG1960	acyl-CoA dehydrogenase activity
BOO69_RS21990	COG1268	BioY protein
BOO69_RS21995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BOO69_RS22020	COG1196	nuclear chromosome segregation
BOO69_RS22020	COG0741	lytic transglycosylase activity
BOO69_RS22020	COG0739	heme binding
BOO69_RS22035	COG3451	type IV secretory pathway VirB4
BOO69_RS22040	COG0741	lytic transglycosylase activity
BOO69_RS22040	COG1196	nuclear chromosome segregation
BOO69_RS22040	COG0739	heme binding
BOO69_RS22060	COG2948	multi-organism process
BOO69_RS22065	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
BOO69_RS22095	COG3505	Type IV secretory pathway VirD4
BOO69_RS22135	COG2003	Belongs to the UPF0758 family
BOO69_RS22195	COG1475	DNA binding
BOO69_RS22200	COG3547	Transposase (IS116 IS110 IS902 family)
BOO69_RS22220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BOO69_RS22225	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BOO69_RS22240	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BOO69_RS22245	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BOO69_RS22245	COG0517	IMP dehydrogenase activity
BOO69_RS22245	COG0617	tRNA 3'-terminal CCA addition
BOO69_RS22250	COG1051	belongs to the nudix hydrolase family
BOO69_RS22260	COG2433	Pfam Transposase IS66
BOO69_RS22265	COG3436	PFAM IS66 Orf2 family protein
BOO69_RS22280	COG0352	thiamine-phosphate diphosphorylase activity
BOO69_RS22290	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BOO69_RS22300	COG1028	Short-chain dehydrogenase reductase Sdr
BOO69_RS22305	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BOO69_RS22315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BOO69_RS22325	COG0431	NADPH-dependent FMN reductase
BOO69_RS22330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BOO69_RS22340	COG3971	2-oxopent-4-enoate hydratase activity
BOO69_RS22345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BOO69_RS22350	COG0596	Alpha beta hydrolase
BOO69_RS22355	COG2368	4-hydroxyphenylacetate
BOO69_RS22395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BOO69_RS22435	COG1196	nuclear chromosome segregation
BOO69_RS22435	COG0741	lytic transglycosylase activity
BOO69_RS22435	COG0739	heme binding
BOO69_RS22450	COG3451	type IV secretory pathway VirB4
BOO69_RS22460	COG1196	nuclear chromosome segregation
BOO69_RS22460	COG0739	heme binding
BOO69_RS22460	COG0741	lytic transglycosylase activity
BOO69_RS22480	COG3736	Type IV secretory pathway, component VirB8
BOO69_RS22490	COG2948	multi-organism process
BOO69_RS22495	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
BOO69_RS22530	COG3843	relaxase mobilization nuclease domain protein
BOO69_RS22580	COG2226	methyltransferase
BOO69_RS22610	COG1414	Transcriptional regulator
BOO69_RS22620	COG1192	Involved in chromosome partitioning
BOO69_RS22660	COG3609	addiction module antidote protein, CC2985 family
BOO69_RS22690	COG1475	DNA binding
BOO69_RS22705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOO69_RS22710	COG1454	alcohol dehydrogenase
BOO69_RS22770	COG0183	Belongs to the thiolase family
BOO69_RS22795	COG1414	Transcriptional regulator
BOO69_RS22825	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BOO69_RS22835	COG2932	Transcriptional regulator
BOO69_RS22930	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BOO69_RS22935	COG4607	ABC-type enterochelin transport system periplasmic component
BOO69_RS23240	COG2323	membrane
BOO69_RS23380	COG3106	COG3106 Predicted ATPase
BOO69_RS23505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOO69_RS23525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOO69_RS23595	COG1858	cytochrome C peroxidase
BOO69_RS23600	COG2200	EAL domain
BOO69_RS23600	COG2199	diguanylate cyclase activity
BOO69_RS23600	COG2202	Pas domain