locus-tag	class	description
SD1155_RS00050	COG2183	response to ionizing radiation
SD1155_RS00055	COG1191	sigma factor activity
SD1155_RS00070	COG2208	phosphoserine phosphatase activity
SD1155_RS00080	COG2337	Toxic component of a toxin-antitoxin (TA) module
SD1155_RS00090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SD1155_RS00095	COG0736	holo-[acyl-carrier-protein] synthase activity
SD1155_RS00105	COG3428	Bacterial PH domain
SD1155_RS00115	COG0513	Belongs to the DEAD box helicase family
SD1155_RS00120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SD1155_RS00125	COG1181	Belongs to the D-alanine--D-alanine ligase family
SD1155_RS00130	COG0772	Belongs to the SEDS family
SD1155_RS00145	COG1937	Protein conserved in bacteria
SD1155_RS00150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SD1155_RS00155	COG1418	mRNA catabolic process
SD1155_RS00160	COG0706	membrane insertase activity
SD1155_RS00165	COG0352	thiamine-phosphate diphosphorylase activity
SD1155_RS00170	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SD1155_RS00180	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SD1155_RS00190	COG0629	single-stranded DNA binding
SD1155_RS00200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SD1155_RS00215	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SD1155_RS00220	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SD1155_RS00235	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SD1155_RS00260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SD1155_RS00265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SD1155_RS00275	COG4475	Protein of unknown function (DUF436)
SD1155_RS00280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SD1155_RS00285	COG0009	L-threonylcarbamoyladenylate synthase
SD1155_RS00290	COG2890	protein-(glutamine-N5) methyltransferase activity
SD1155_RS00300	COG1435	thymidine kinase activity
SD1155_RS00310	COG0254	rRNA binding
SD1155_RS00315	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SD1155_RS00320	COG1012	belongs to the aldehyde dehydrogenase family
SD1155_RS00335	COG0191	fructose-bisphosphate aldolase activity
SD1155_RS00345	COG0504	CTP synthase activity
SD1155_RS00380	COG1854	S-ribosylhomocysteine lyase activity
SD1155_RS00390	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SD1155_RS00395	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SD1155_RS00400	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SD1155_RS00405	COG0813	purine-nucleoside phosphorylase activity
SD1155_RS00410	COG0783	Belongs to the Dps family
SD1155_RS00430	COG1482	cell wall glycoprotein biosynthetic process
SD1155_RS00435	COG0702	epimerase
SD1155_RS00440	COG0640	Transcriptional regulator
SD1155_RS00460	COG0561	phosphatase activity
SD1155_RS00475	COG3711	transcriptional antiterminator
SD1155_RS00500	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SD1155_RS00555	COG0489	protein tyrosine kinase activity
SD1155_RS00560	COG2814	Major facilitator Superfamily
SD1155_RS00575	COG1272	protein, Hemolysin III
SD1155_RS00580	COG4284	Utp--glucose-1-phosphate uridylyltransferase
SD1155_RS00585	COG1988	membrane-bound metal-dependent
SD1155_RS00595	COG2329	Antibiotic biosynthesis monooxygenase
SD1155_RS00600	COG3314	Sporulation integral membrane protein YlbJ
SD1155_RS00605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD1155_RS00610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD1155_RS00615	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SD1155_RS00620	COG3457	Alanine racemase
SD1155_RS00625	COG4264	IucA IucC family
SD1155_RS00630	COG2814	Major facilitator Superfamily
SD1155_RS00640	COG1302	Protein conserved in bacteria
SD1155_RS00655	COG0604	alcohol dehydrogenase
SD1155_RS00660	COG2130	NADP-dependent
SD1155_RS00665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SD1155_RS00705	COG0698	ribose 5-phosphate isomerase
SD1155_RS00735	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SD1155_RS00740	COG0101	tRNA pseudouridine synthase activity
SD1155_RS00750	COG1122	ATPase activity
SD1155_RS00765	COG0202	RNA polymerase activity
SD1155_RS00770	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SD1155_RS00775	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SD1155_RS00785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SD1155_RS00790	COG0563	adenylate kinase activity
SD1155_RS00795	COG0201	protein transport
SD1155_RS00805	COG1841	ribosomal large subunit assembly
SD1155_RS00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SD1155_RS00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SD1155_RS00820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SD1155_RS00825	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SD1155_RS00830	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SD1155_RS00840	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SD1155_RS00845	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SD1155_RS00850	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SD1155_RS00860	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SD1155_RS00865	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SD1155_RS00870	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SD1155_RS00875	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SD1155_RS00880	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SD1155_RS00885	COG0089	rRNA binding
SD1155_RS00890	COG0088	Forms part of the polypeptide exit tunnel
SD1155_RS00895	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SD1155_RS00910	COG2252	PERMEase
SD1155_RS00925	COG4975	Glucose uptake
SD1155_RS00945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SD1155_RS00950	COG2348	transferase activity, transferring amino-acyl groups
SD1155_RS00970	COG2814	Major facilitator Superfamily
SD1155_RS00980	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SD1155_RS00985	COG0746	molybdenum cofactor guanylyltransferase activity
SD1155_RS01000	COG1763	Mo-molybdopterin cofactor biosynthetic process
SD1155_RS01010	COG0315	cyclic pyranopterin monophosphate synthase activity
SD1155_RS01015	COG0521	Mo-molybdopterin cofactor biosynthetic process
SD1155_RS01020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SD1155_RS01030	COG4149	molybdate abc transporter
SD1155_RS01035	COG0725	ABC transporter, periplasmic molybdate-binding protein
SD1155_RS01050	COG1268	BioY protein
SD1155_RS01065	COG1960	acyl-CoA dehydrogenase activity
SD1155_RS01070	COG1126	abc transporter atp-binding protein
SD1155_RS01075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SD1155_RS01080	COG0765	amino acid transport
SD1155_RS01085	COG0765	amino acid transport
SD1155_RS01090	COG4413	Urea transporter
SD1155_RS01095	COG0831	urea catabolic process
SD1155_RS01105	COG0804	urea catabolic process
SD1155_RS01110	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SD1155_RS01125	COG0829	nickel cation binding
SD1155_RS01140	COG1846	Transcriptional regulator
SD1155_RS01150	COG3942	CHAP domain
SD1155_RS01155	COG1757	Na H antiporter
SD1155_RS01170	COG3942	CHAP domain
SD1155_RS01175	COG2076	Multidrug Resistance protein
SD1155_RS01180	COG2076	Multidrug Resistance protein
SD1155_RS01185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SD1155_RS01215	COG1316	TRANSCRIPTIONal
SD1155_RS01225	COG1349	DNA-binding transcription factor activity
SD1155_RS01230	COG1266	CAAX protease self-immunity
SD1155_RS01245	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SD1155_RS01250	COG1263	PTS System
SD1155_RS01250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD1155_RS01260	COG1113	amino acid transport
SD1155_RS01280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SD1155_RS01285	COG0385	Bile acid
SD1155_RS01295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD1155_RS01295	COG1263	PTS System
SD1155_RS01300	COG1737	Transcriptional regulator
SD1155_RS01320	COG1028	Short-chain dehydrogenase reductase Sdr
SD1155_RS01325	COG1473	amidohydrolase
SD1155_RS01330	COG0659	secondary active sulfate transmembrane transporter activity
SD1155_RS01345	COG0583	DNA-binding transcription factor activity
SD1155_RS01350	COG0010	Belongs to the arginase family
SD1155_RS01355	COG1266	CAAX protease self-immunity
SD1155_RS01365	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SD1155_RS01370	COG2258	MOSC domain
SD1155_RS01375	COG2017	converts alpha-aldose to the beta-anomer
SD1155_RS01380	COG1742	UPF0060 membrane protein
SD1155_RS01385	COG1668	transmembrane transport
SD1155_RS01390	COG4152	abc transporter atp-binding protein
SD1155_RS01395	COG1069	ribulokinase activity
SD1155_RS01405	COG3620	sequence-specific DNA binding
SD1155_RS01415	COG2094	Belongs to the DNA glycosylase MPG family
SD1155_RS01430	COG1695	Transcriptional regulator
SD1155_RS01435	COG0786	glutamate:sodium symporter activity
SD1155_RS01440	COG1304	FMN binding
SD1155_RS01445	COG0598	Magnesium transport protein CorA
SD1155_RS01470	COG2814	Major facilitator Superfamily
SD1155_RS01475	COG1566	PFAM secretion protein HlyD family protein
SD1155_RS01485	COG2814	Major facilitator Superfamily
SD1155_RS01520	COG5002	protein histidine kinase activity
SD1155_RS01520	COG3850	Histidine kinase
SD1155_RS01535	COG0579	oxidoreductase
SD1155_RS01540	COG0438	transferase activity, transferring glycosyl groups
SD1155_RS01545	COG1620	l-lactate permease
SD1155_RS01550	COG0463	Glycosyl transferase, family 2
SD1155_RS01550	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SD1155_RS01560	COG0463	Glycosyl transferase, family 2
SD1155_RS01560	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SD1155_RS01570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SD1155_RS01575	COG0805	protein transport
SD1155_RS01580	COG0672	)-iron permease
SD1155_RS01585	COG2837	iron assimilation
SD1155_RS01590	COG2822	iron ion transport
SD1155_RS01595	COG0604	alcohol dehydrogenase
SD1155_RS01600	COG0456	acetyltransferase
SD1155_RS01605	COG0492	ferredoxin-NADP+ reductase activity
SD1155_RS01635	COG1028	Short-chain dehydrogenase reductase Sdr
SD1155_RS01645	COG0583	DNA-binding transcription factor activity
SD1155_RS01650	COG2610	gluconate transmembrane transporter activity
SD1155_RS01655	COG1028	Short-chain dehydrogenase reductase Sdr
SD1155_RS01665	COG1511	domain protein
SD1155_RS01680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD1155_RS01680	COG1263	PTS System
SD1155_RS01715	COG0778	Nitroreductase
SD1155_RS01730	COG2223	nitrite transmembrane transporter activity
SD1155_RS01740	COG4585	Histidine kinase
SD1155_RS01750	COG2181	nitrate reductase activity
SD1155_RS01760	COG1140	nitrate reductase beta subunit
SD1155_RS01765	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SD1155_RS01775	COG2146	nitrite reductase [NAD(P)H] activity
SD1155_RS01780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SD1155_RS01790	COG0747	negative chemotaxis
SD1155_RS01795	COG0454	-acetyltransferase
SD1155_RS01815	COG0803	Belongs to the bacterial solute-binding protein 9 family
SD1155_RS01830	COG2348	transferase activity, transferring amino-acyl groups
SD1155_RS01835	COG1126	abc transporter atp-binding protein
SD1155_RS01840	COG0765	amino acid transport
SD1155_RS01845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SD1155_RS01850	COG2814	Major facilitator Superfamily
SD1155_RS01860	COG0588	phosphoglycerate mutase activity
SD1155_RS01865	COG0741	lytic transglycosylase activity
SD1155_RS01870	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SD1155_RS01885	COG1929	Belongs to the glycerate kinase type-1 family
SD1155_RS01895	COG2814	Major facilitator Superfamily
SD1155_RS01910	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SD1155_RS01915	COG1113	amino acid transport
SD1155_RS01920	COG0025	NhaP-type Na H and K H
SD1155_RS01925	COG0531	amino acid
SD1155_RS01935	COG0706	membrane insertase activity
SD1155_RS01945	COG3477	response to acidic pH
SD1155_RS01955	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SD1155_RS01965	COG1380	Effector of murein hydrolase LrgA
SD1155_RS01970	COG1346	cytolysis
SD1155_RS01975	COG1174	glycine betaine transport
SD1155_RS02000	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SD1155_RS02005	COG0531	amino acid
SD1155_RS02010	COG2272	Belongs to the type-B carboxylesterase lipase family
SD1155_RS02015	COG2814	Major facilitator Superfamily
SD1155_RS02025	COG0745	RESPONSE REGULATOR receiver
SD1155_RS02030	COG2205	protein histidine kinase activity
SD1155_RS02035	COG0390	transport system, permease component
SD1155_RS02040	COG4619	ABC transporter
SD1155_RS02045	COG1266	CAAX protease self-immunity
SD1155_RS02055	COG0069	glutamate synthase activity
SD1155_RS02070	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SD1155_RS02075	COG4808	Protein conserved in bacteria
SD1155_RS02080	COG1363	Peptidase, m42
SD1155_RS02085	COG1028	Short-chain dehydrogenase reductase Sdr
SD1155_RS02090	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SD1155_RS02100	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SD1155_RS02105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SD1155_RS02135	COG0508	dehydrogenase complex catalyzes the overall conversion of
SD1155_RS02140	COG0022	dehydrogenase e1 component
SD1155_RS02145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SD1155_RS02150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SD1155_RS02160	COG0494	nUDIX hydrolase
SD1155_RS02165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SD1155_RS02170	COG1215	transferase activity, transferring glycosyl groups
SD1155_RS02185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SD1155_RS02195	COG1070	Carbohydrate kinase
SD1155_RS02200	COG1802	Transcriptional regulator
SD1155_RS02215	COG2357	RelA SpoT domain protein
SD1155_RS02220	COG4876	unkown
SD1155_RS02230	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
SD1155_RS02240	COG0352	thiamine-phosphate diphosphorylase activity
SD1155_RS02245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SD1155_RS02255	COG2022	thiamine diphosphate biosynthetic process
SD1155_RS02260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SD1155_RS02265	COG0586	Pfam SNARE associated Golgi protein
SD1155_RS02270	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
SD1155_RS02280	COG3949	Membrane
SD1155_RS02285	COG1012	belongs to the aldehyde dehydrogenase family
SD1155_RS02290	COG0583	DNA-binding transcription factor activity
SD1155_RS02305	COG2514	catechol 2,3-dioxygenase activity
SD1155_RS02330	COG1012	belongs to the aldehyde dehydrogenase family
SD1155_RS02335	COG0778	Nitroreductase
SD1155_RS02340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SD1155_RS02350	COG3764	Sortase (surface protein transpeptidase)
SD1155_RS02365	COG1760	l-serine dehydratase
SD1155_RS02370	COG1760	l-serine dehydratase
SD1155_RS02380	COG1070	Carbohydrate kinase
SD1155_RS02400	COG2843	Capsule synthesis protein
SD1155_RS02410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SD1155_RS02420	COG0657	acetylesterase activity
SD1155_RS02425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SD1155_RS02430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SD1155_RS02455	COG0028	Belongs to the TPP enzyme family
SD1155_RS02460	COG1346	cytolysis
SD1155_RS02465	COG1380	Effector of murein hydrolase LrgA
SD1155_RS02470	COG0583	DNA-binding transcription factor activity
SD1155_RS02480	COG3942	CHAP domain
SD1155_RS02480	COG1388	LysM domain
SD1155_RS02490	COG3425	synthase
SD1155_RS02495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SD1155_RS02505	COG0598	Magnesium transport protein CorA
SD1155_RS02535	COG1012	belongs to the aldehyde dehydrogenase family
SD1155_RS02545	COG1028	Short-chain dehydrogenase reductase Sdr
SD1155_RS02560	COG2608	mercury ion transmembrane transporter activity
SD1155_RS02570	COG0436	Aminotransferase
SD1155_RS02585	COG0741	lytic transglycosylase activity
SD1155_RS02640	COG4221	oxidoreductase activity
SD1155_RS02650	COG0596	Alpha beta hydrolase
SD1155_RS02660	COG3001	Fructosamine kinase
SD1155_RS02665	COG0167	dihydroorotate dehydrogenase activity
SD1155_RS02675	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SD1155_RS02705	COG4640	response to antibiotic
SD1155_RS02720	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SD1155_RS02725	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SD1155_RS02735	COG3527	Alpha-acetolactate decarboxylase
SD1155_RS02740	COG0028	Belongs to the TPP enzyme family
SD1155_RS02745	COG0039	L-malate dehydrogenase activity
SD1155_RS02750	COG0583	DNA-binding transcription factor activity
SD1155_RS02760	COG0531	amino acid
SD1155_RS02785	COG0446	pyridine nucleotide-disulphide oxidoreductase
SD1155_RS02795	COG0563	adenylate kinase activity
SD1155_RS02800	COG3588	fructose-bisphosphate aldolase
SD1155_RS02805	COG1695	Transcriptional regulator
SD1155_RS02815	COG2723	6-phospho-beta-galactosidase activity
SD1155_RS02820	COG2190	(PTS) system
SD1155_RS02820	COG1263	PTS System
SD1155_RS02820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD1155_RS02830	COG0579	oxidoreductase
SD1155_RS02835	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SD1155_RS02840	COG0574	Belongs to the PEP-utilizing enzyme family
SD1155_RS02840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SD1155_RS02845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SD1155_RS02865	COG1473	amidohydrolase
SD1155_RS02870	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SD1155_RS02875	COG1012	belongs to the aldehyde dehydrogenase family
SD1155_RS02880	COG1510	regulation of RNA biosynthetic process
SD1155_RS02890	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
SD1155_RS02895	COG0602	queuosine metabolic process
SD1155_RS02900	COG1328	CTP reductase activity
SD1155_RS02905	COG3942	CHAP domain
SD1155_RS02915	COG0529	Catalyzes the synthesis of activated sulfate
SD1155_RS02920	COG2046	Belongs to the sulfate adenylyltransferase family
SD1155_RS02925	COG0730	response to heat
SD1155_RS02940	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SD1155_RS02945	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SD1155_RS02950	COG0175	sulfate reduction
SD1155_RS02980	COG1136	(ABC) transporter
SD1155_RS02985	COG2205	protein histidine kinase activity
SD1155_RS02990	COG0745	RESPONSE REGULATOR receiver
SD1155_RS02995	COG1785	Belongs to the alkaline phosphatase family
SD1155_RS03005	COG4195	phage-related replication protein
SD1155_RS03015	COG3961	Belongs to the TPP enzyme family
SD1155_RS03030	COG2843	Capsule synthesis protein
SD1155_RS03035	COG3227	Zinc metalloprotease (Elastase)
SD1155_RS03040	COG0739	heme binding
SD1155_RS03050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SD1155_RS03070	COG3942	CHAP domain
SD1155_RS03070	COG1705	Flagellar rod assembly protein muramidase FlgJ
SD1155_RS03080	COG1764	response to oxidative stress
SD1155_RS03085	COG2409	Drug exporters of the RND superfamily
SD1155_RS03090	COG2113	Glycine betaine
SD1155_RS03110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SD1155_RS03185	COG0737	Belongs to the 5'-nucleotidase family
SD1155_RS03190	COG2814	Major facilitator Superfamily
SD1155_RS03205	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SD1155_RS03240	COG1288	antiporter activity
SD1155_RS03265	COG1054	Belongs to the UPF0176 family
SD1155_RS03270	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SD1155_RS03285	COG1695	Transcriptional regulator
SD1155_RS03295	COG0471	metal ion transport
SD1155_RS03300	COG2962	Rard protein
SD1155_RS03305	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
SD1155_RS03310	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SD1155_RS03315	COG4221	oxidoreductase activity
SD1155_RS03330	COG1136	(ABC) transporter
SD1155_RS03340	COG2205	protein histidine kinase activity
SD1155_RS03350	COG1131	(ABC) transporter
SD1155_RS03355	COG0745	RESPONSE REGULATOR receiver
SD1155_RS03440	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SD1155_RS03455	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SD1155_RS03455	COG0463	Glycosyl transferase, family 2
SD1155_RS03460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SD1155_RS03465	COG1288	antiporter activity
SD1155_RS03475	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SD1155_RS03480	COG1882	Formate acetyltransferase
SD1155_RS03485	COG1876	peptidase activity
SD1155_RS03490	COG2910	NAD(P)H-binding
SD1155_RS03495	COG1959	2 iron, 2 sulfur cluster binding
SD1155_RS03505	COG2259	Doxx family
SD1155_RS03520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SD1155_RS03525	COG0656	L-ascorbic acid biosynthetic process
SD1155_RS03530	COG0789	Transcriptional regulator
SD1155_RS03535	COG1124	(ABC) transporter
SD1155_RS03545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SD1155_RS03550	COG0601	transmembrane transport
SD1155_RS03555	COG0747	negative chemotaxis
SD1155_RS03570	COG0201	protein transport
SD1155_RS03580	COG1073	alpha beta
SD1155_RS03590	COG0653	protein targeting
SD1155_RS03595	COG0438	transferase activity, transferring glycosyl groups
SD1155_RS03620	COG0659	secondary active sulfate transmembrane transporter activity
SD1155_RS03625	COG1438	arginine binding
SD1155_RS03630	COG2235	arginine
SD1155_RS03650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SD1155_RS03655	COG1250	3-hydroxyacyl-CoA dehydrogenase
SD1155_RS03675	COG0706	membrane insertase activity
SD1155_RS03680	COG1482	cell wall glycoprotein biosynthetic process
SD1155_RS03685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SD1155_RS03685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SD1155_RS03685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SD1155_RS03690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SD1155_RS03690	COG3711	transcriptional antiterminator
SD1155_RS03715	COG1518	maintenance of DNA repeat elements
SD1155_RS03725	COG0346	lactoylglutathione lyase activity
SD1155_RS03740	COG1124	(ABC) transporter
SD1155_RS03745	COG0444	Belongs to the ABC transporter superfamily
SD1155_RS03755	COG0601	transmembrane transport
SD1155_RS03785	COG1131	(ABC) transporter
SD1155_RS03805	COG2814	Major facilitator Superfamily
SD1155_RS03830	COG1869	D-ribose catabolic process
SD1155_RS03840	COG1609	Transcriptional regulator
SD1155_RS03845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SD1155_RS03890	COG2814	Major facilitator Superfamily
SD1155_RS03895	COG1114	Component of the transport system for branched-chain amino acids
SD1155_RS03905	COG0110	maltose O-acetyltransferase activity
SD1155_RS03910	COG0583	DNA-binding transcription factor activity
SD1155_RS03920	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SD1155_RS03925	COG0583	DNA-binding transcription factor activity
SD1155_RS03935	COG0025	NhaP-type Na H and K H
SD1155_RS03940	COG0789	Transcriptional regulator
SD1155_RS03950	COG0656	L-ascorbic acid biosynthetic process
SD1155_RS03955	COG0110	maltose O-acetyltransferase activity
SD1155_RS03960	COG2808	Putative FMN-binding domain
SD1155_RS03985	COG2226	methyltransferase
SD1155_RS03990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SD1155_RS03995	COG2814	Major facilitator Superfamily
SD1155_RS04000	COG0300	oxidoreductase activity
SD1155_RS04005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SD1155_RS04010	COG2851	Citrate transporter
SD1155_RS04055	COG1733	regulation of RNA biosynthetic process
SD1155_RS04060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SD1155_RS04070	COG3223	Belongs to the PsiE family
SD1155_RS04105	COG1401	restriction endodeoxyribonuclease activity
SD1155_RS04115	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SD1155_RS04130	COG5002	protein histidine kinase activity
SD1155_RS04135	COG0745	RESPONSE REGULATOR receiver
SD1155_RS04155	COG0305	Participates in initiation and elongation during chromosome replication
SD1155_RS04160	COG0359	binds to the 23S rRNA
SD1155_RS04165	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SD1155_RS04175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SD1155_RS04185	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SD1155_RS04200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SD1155_RS04205	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SD1155_RS04210	COG0187	DNA topoisomerase II activity
SD1155_RS04215	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SD1155_RS04220	COG2501	S4 domain
SD1155_RS04225	COG0592	DNA-directed DNA polymerase activity
SD1155_RS04230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SD1155_RS04240	COG0594	ribonuclease P activity
SD1155_RS04245	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SD1155_RS04250	COG0445	tRNA wobble uridine modification
SD1155_RS04255	COG0357	Ribosomal RNA small subunit methyltransferase G
SD1155_RS04260	COG1475	DNA binding
SD1155_RS04300	COG1136	(ABC) transporter
SD1155_RS04305	COG0577	efflux transmembrane transporter activity
SD1155_RS04330	COG1073	alpha beta
SD1155_RS04345	COG1063	alcohol dehydrogenase
SD1155_RS04355	COG2348	transferase activity, transferring amino-acyl groups
SD1155_RS04370	COG1682	transport, permease protein
SD1155_RS04425	COG0577	efflux transmembrane transporter activity
SD1155_RS04430	COG1136	(ABC) transporter
SD1155_RS04450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SD1155_RS04465	COG1131	(ABC) transporter
SD1155_RS04475	COG1476	TRANSCRIPTIONal
SD1155_RS04505	COG0183	Belongs to the thiolase family
SD1155_RS04535	COG2814	Major facilitator Superfamily
SD1155_RS04540	COG0640	Transcriptional regulator
SD1155_RS04545	COG3942	CHAP domain
SD1155_RS04560	COG1309	transcriptional regulator
SD1155_RS04590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SD1155_RS04595	COG0646	methionine synthase
SD1155_RS04595	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SD1155_RS04600	COG0626	cystathionine gamma-synthase activity
SD1155_RS04605	COG0626	cystathionine gamma-synthase activity
SD1155_RS04615	COG1475	DNA binding
SD1155_RS04620	COG0668	transmembrane transport
SD1155_RS04625	COG4481	Protein conserved in bacteria
SD1155_RS04630	COG0012	GTP binding
SD1155_RS04645	COG0360	Binds together with S18 to 16S ribosomal RNA
SD1155_RS04655	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SD1155_RS04665	COG0582	viral genome integration into host DNA
SD1155_RS04735	COG5484	DNA packaging
SD1155_RS04735	COG3728	DNA packaging
SD1155_RS04755	COG1280	lysine exporter protein (LysE YggA)
SD1155_RS04780	COG3634	alkyl hydroperoxide reductase activity
SD1155_RS04785	COG0450	alkyl hydroperoxide reductase
SD1155_RS04790	COG0778	Nitroreductase
SD1155_RS04795	COG1823	symporter activity
SD1155_RS04800	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SD1155_RS04805	COG5183	chlorophyll binding
SD1155_RS04820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SD1155_RS04825	COG2233	PERMEase
SD1155_RS04830	COG0517	IMP dehydrogenase activity
SD1155_RS04830	COG0516	GMP reductase activity
SD1155_RS04835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SD1155_RS04835	COG0519	Catalyzes the synthesis of GMP from XMP
SD1155_RS04845	COG0523	cobalamin synthesis protein
SD1155_RS04860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SD1155_RS04865	COG3002	Belongs to the UPF0753 family
SD1155_RS04870	COG5609	conserved protein (DUF2294)
SD1155_RS04885	COG0671	phosphoesterase, PA-phosphatase related
SD1155_RS04890	COG1647	Serine aminopeptidase, S33
SD1155_RS04900	COG0733	neurotransmitter:sodium symporter activity
SD1155_RS04905	COG1279	arginine transmembrane transporter activity
SD1155_RS04920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SD1155_RS04925	COG0626	cystathionine gamma-synthase activity
SD1155_RS04930	COG1846	Transcriptional regulator
SD1155_RS04955	COG3759	membrane
SD1155_RS04960	COG1278	Cold shock
SD1155_RS04970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SD1155_RS04975	COG0438	transferase activity, transferring glycosyl groups
SD1155_RS04985	COG0494	nUDIX hydrolase
SD1155_RS04990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SD1155_RS05010	COG0067	glutamate synthase
SD1155_RS05010	COG0069	glutamate synthase activity
SD1155_RS05010	COG0070	glutamate synthase
SD1155_RS05015	COG0493	'glutamate synthase
SD1155_RS05030	COG0366	Alpha amylase catalytic
SD1155_RS05035	COG2188	Transcriptional regulator
SD1155_RS05050	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SD1155_RS05060	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SD1155_RS05080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SD1155_RS05085	COG1982	Orn Lys Arg decarboxylase major
SD1155_RS05095	COG3870	Protein conserved in bacteria
SD1155_RS05100	COG0470	DNA polymerase III
SD1155_RS05105	COG1774	PSP1 C-terminal conserved region
SD1155_RS05110	COG4467	Involved in initiation control of chromosome replication
SD1155_RS05115	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SD1155_RS05120	COG2827	Endonuclease containing a URI domain
SD1155_RS05125	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SD1155_RS05130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SD1155_RS05130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SD1155_RS05135	COG0084	hydrolase, TatD family'
SD1155_RS05140	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SD1155_RS05145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SD1155_RS05150	COG4466	Protein conserved in bacteria
SD1155_RS05155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SD1155_RS05160	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SD1155_RS05165	COG0251	oxidation-reduction process
SD1155_RS05170	COG2088	sporulation resulting in formation of a cellular spore
SD1155_RS05175	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SD1155_RS05180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SD1155_RS05185	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SD1155_RS05190	COG0193	aminoacyl-tRNA hydrolase activity
SD1155_RS05195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SD1155_RS05200	COG2244	polysaccharide biosynthetic process
SD1155_RS05205	COG3956	TIGRFAM MazG family protein
SD1155_RS05210	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SD1155_RS05220	COG1098	S1 RNA binding domain
SD1155_RS05235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SD1155_RS05255	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SD1155_RS05260	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SD1155_RS05265	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SD1155_RS05330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SD1155_RS05335	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SD1155_RS05340	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SD1155_RS05345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SD1155_RS05355	COG3880	PFAM UvrB UvrC protein
SD1155_RS05360	COG3869	Catalyzes the specific phosphorylation of arginine residues in
SD1155_RS05365	COG0542	response to heat
SD1155_RS05370	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SD1155_RS05375	COG4956	integral membrane protein (PIN domain superfamily)
SD1155_RS05380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SD1155_RS05390	COG0215	cysteine-tRNA ligase activity
SD1155_RS05395	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SD1155_RS05405	COG3688	RNA-binding protein containing a PIN domain
SD1155_RS05415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SD1155_RS05425	COG0250	Participates in transcription elongation, termination and antitermination
SD1155_RS05430	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SD1155_RS05435	COG0081	regulation of translation
SD1155_RS05445	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SD1155_RS05450	COG0222	ribosome binding
SD1155_RS05455	COG2813	Specifically methylates the guanine in position
SD1155_RS05460	COG0085	RNA polymerase activity
SD1155_RS05465	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SD1155_RS05475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SD1155_RS05480	COG0049	tRNA binding
SD1155_RS05485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SD1155_RS05490	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SD1155_RS05495	COG1473	amidohydrolase
SD1155_RS05520	COG1349	DNA-binding transcription factor activity
SD1155_RS05525	COG2814	Major facilitator Superfamily
SD1155_RS05530	COG1063	alcohol dehydrogenase
SD1155_RS05555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SD1155_RS05560	COG0546	phosphoglycolate phosphatase activity
SD1155_RS05565	COG1428	Deoxynucleoside kinase
SD1155_RS05570	COG1428	Deoxynucleoside kinase
SD1155_RS05580	COG0561	phosphatase activity
SD1155_RS05585	COG0431	NADPH-dependent FMN reductase
SD1155_RS05605	COG0438	transferase activity, transferring glycosyl groups
SD1155_RS05610	COG2271	Major facilitator Superfamily
SD1155_RS05615	COG1469	GTP cyclohydrolase I activity
SD1155_RS05620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SD1155_RS05630	COG0363	glucosamine-6-phosphate deaminase activity
SD1155_RS05635	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SD1155_RS05650	COG0477	Major facilitator Superfamily
SD1155_RS05670	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
SD1155_RS05685	COG2363	Small membrane protein
SD1155_RS05705	COG3253	May function as heme-dependent peroxidase
SD1155_RS05710	COG0280	phosphate acetyltransferase
SD1155_RS05715	COG0095	Lipoate-protein ligase
SD1155_RS05720	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SD1155_RS05735	COG4844	belongs to the
SD1155_RS05740	COG0667	Aldo Keto reductase
SD1155_RS05745	COG0655	NAD(P)H dehydrogenase (quinone) activity
SD1155_RS05750	COG0519	Catalyzes the synthesis of GMP from XMP
SD1155_RS05755	COG1078	dGTPase activity
SD1155_RS05765	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SD1155_RS05770	COG1691	(AIR) carboxylase
SD1155_RS05775	COG1606	tRNA processing
SD1155_RS05780	COG3875	lactate racemase activity
SD1155_RS05795	COG0018	arginyl-trna synthetase
SD1155_RS05800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SD1155_RS05815	COG0534	Mate efflux family protein
SD1155_RS05820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SD1155_RS05825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD1155_RS05830	COG0546	phosphoglycolate phosphatase activity
SD1155_RS05850	COG2267	carboxylic ester hydrolase activity
SD1155_RS05885	COG2111	Na H antiporter
SD1155_RS05885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SD1155_RS05890	COG2111	Na H antiporter
SD1155_RS05895	COG1006	Multisubunit Na H antiporter MnhC subunit
SD1155_RS05900	COG0651	ATP synthesis coupled electron transport
SD1155_RS05905	COG1863	multisubunit Na H antiporter MnhE subunit
SD1155_RS05915	COG1320	monovalent cation:proton antiporter activity
SD1155_RS05925	COG0803	Belongs to the bacterial solute-binding protein 9 family
SD1155_RS05930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SD1155_RS05935	COG1121	(ABC) transporter
SD1155_RS05950	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SD1155_RS05955	COG1134	teichoic acid transport
SD1155_RS05960	COG1682	transport, permease protein
SD1155_RS05965	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SD1155_RS05975	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SD1155_RS05980	COG1686	Belongs to the peptidase S11 family
SD1155_RS05985	COG1132	(ABC) transporter
SD1155_RS05990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SD1155_RS05995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SD1155_RS06000	COG1120	ATPase activity
SD1155_RS06005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD1155_RS06010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD1155_RS06015	COG2376	Dihydroxyacetone kinase
SD1155_RS06025	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SD1155_RS06035	COG3949	Membrane
SD1155_RS06040	COG0657	acetylesterase activity
SD1155_RS06050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SD1155_RS06060	COG2205	protein histidine kinase activity
SD1155_RS06065	COG1136	(ABC) transporter
SD1155_RS06070	COG0577	efflux transmembrane transporter activity
SD1155_RS06080	COG1392	Phosphate transport regulator
SD1155_RS06085	COG0306	phosphate transporter
SD1155_RS06095	COG3942	CHAP domain
SD1155_RS06095	COG1388	LysM domain
SD1155_RS06105	COG2169	Transcriptional regulator
SD1155_RS06115	COG0217	transcriptional regulatory protein
SD1155_RS06130	COG0583	DNA-binding transcription factor activity
SD1155_RS06135	COG2814	Major facilitator Superfamily
SD1155_RS06140	COG2839	Protein conserved in bacteria
SD1155_RS06165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SD1155_RS06175	COG1959	2 iron, 2 sulfur cluster binding
SD1155_RS06180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SD1155_RS06190	COG1671	Belongs to the UPF0178 family
SD1155_RS06200	COG1968	undecaprenyl-diphosphatase activity
SD1155_RS06205	COG4988	ABC transporter
SD1155_RS06210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SD1155_RS06220	COG0523	cobalamin synthesis protein
SD1155_RS06225	COG4989	oxidoreductase activity
SD1155_RS06235	COG0039	L-malate dehydrogenase activity
SD1155_RS06240	COG0471	metal ion transport
SD1155_RS06245	COG0415	Belongs to the DNA photolyase family
SD1155_RS06270	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SD1155_RS06275	COG1349	DNA-binding transcription factor activity
SD1155_RS06280	COG1105	Belongs to the carbohydrate kinase PfkB family
SD1155_RS06285	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SD1155_RS06285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SD1155_RS06285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SD1155_RS06290	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SD1155_RS06295	COG1253	flavin adenine dinucleotide binding
SD1155_RS06300	COG0656	L-ascorbic acid biosynthetic process
SD1155_RS06305	COG0463	Glycosyl transferase, family 2
SD1155_RS06320	COG0720	synthase
SD1155_RS06325	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SD1155_RS06330	COG0512	Glutamine amidotransferase of anthranilate synthase
SD1155_RS06330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SD1155_RS06360	COG1368	sulfuric ester hydrolase activity
SD1155_RS06370	COG0488	(ABC) transporter
SD1155_RS06375	COG0514	ATP-dependent DNA helicase (RecQ)
SD1155_RS06385	COG1174	glycine betaine transport
SD1155_RS06390	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SD1155_RS06400	COG1597	lipid kinase activity
SD1155_RS06405	COG3104	oligopeptide transport
SD1155_RS06420	COG1780	Probably involved in ribonucleotide reductase function
SD1155_RS06425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SD1155_RS06430	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SD1155_RS06435	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SD1155_RS06440	COG4605	iron ion homeostasis
SD1155_RS06445	COG4604	ABC transporter, ATP-binding protein
SD1155_RS06460	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SD1155_RS06480	COG1929	Belongs to the glycerate kinase type-1 family
SD1155_RS06485	COG2195	Cleaves the N-terminal amino acid of tripeptides
SD1155_RS06505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SD1155_RS06510	COG1739	Uncharacterized protein family UPF0029
SD1155_RS06520	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SD1155_RS06525	COG1040	competence protein
SD1155_RS06530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SD1155_RS06535	COG0653	protein targeting
SD1155_RS06545	COG3942	CHAP domain
SD1155_RS06545	COG1388	LysM domain
SD1155_RS06560	COG0556	nucleotide-excision repair
SD1155_RS06565	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SD1155_RS06575	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SD1155_RS06590	COG0492	ferredoxin-NADP+ reductase activity
SD1155_RS06595	COG1660	Displays ATPase and GTPase activities
SD1155_RS06600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SD1155_RS06605	COG1481	regulation of sporulation
SD1155_RS06615	COG0740	serine-type endopeptidase activity
SD1155_RS06640	COG2390	Transcriptional regulator
SD1155_RS06650	COG0126	phosphoglycerate kinase activity
SD1155_RS06655	COG0149	triose-phosphate isomerase activity
SD1155_RS06660	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SD1155_RS06665	COG0148	phosphopyruvate hydratase activity
SD1155_RS06675	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SD1155_RS06680	COG1647	Serine aminopeptidase, S33
SD1155_RS06685	COG0557	exoribonuclease II activity
SD1155_RS06755	COG1309	transcriptional regulator
SD1155_RS06760	COG0656	L-ascorbic acid biosynthetic process
SD1155_RS06785	COG1278	Cold shock
SD1155_RS06845	COG0406	alpha-ribazole phosphatase activity
SD1155_RS06855	COG1764	response to oxidative stress
SD1155_RS06860	COG0710	3-dehydroquinate dehydratase activity
SD1155_RS06870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SD1155_RS06875	COG1393	Belongs to the ArsC family
SD1155_RS06880	COG0509	glycine decarboxylation via glycine cleavage system
SD1155_RS06885	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SD1155_RS06895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SD1155_RS06900	COG2011	ABC-type metal ion transport system permease component
SD1155_RS06905	COG1464	Belongs to the NlpA lipoprotein family
SD1155_RS06910	COG3237	CsbD-like
SD1155_RS06920	COG0396	ATPase activity
SD1155_RS06925	COG0719	Fe-S assembly protein
SD1155_RS06930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SD1155_RS06935	COG0822	iron-sulfur transferase activity
SD1155_RS06940	COG0719	Fe-S assembly protein
SD1155_RS06945	COG1253	flavin adenine dinucleotide binding
SD1155_RS06950	COG2070	2-Nitropropane dioxygenase
SD1155_RS06955	COG1801	Protein of unknown function DUF72
SD1155_RS06960	COG0730	response to heat
SD1155_RS06965	COG0737	Belongs to the 5'-nucleotidase family
SD1155_RS06970	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SD1155_RS06975	COG4470	Protein conserved in bacteria
SD1155_RS06985	COG2445	Protein of unknown function DUF86
SD1155_RS07005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SD1155_RS07010	COG1696	Membrane protein involved in D-alanine export
SD1155_RS07020	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SD1155_RS07030	COG0583	DNA-binding transcription factor activity
SD1155_RS07035	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SD1155_RS07040	COG4837	Protein of unknown function (DUF1462)
SD1155_RS07045	COG1252	NADH dehydrogenase
SD1155_RS07050	COG4844	belongs to the
SD1155_RS07055	COG0316	Belongs to the HesB IscA family
SD1155_RS07070	COG2056	Na+-H+ antiporter family
SD1155_RS07075	COG2050	protein possibly involved in aromatic compounds catabolism
SD1155_RS07085	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SD1155_RS07095	COG2212	antiporter activity
SD1155_RS07105	COG0651	ATP synthesis coupled electron transport
SD1155_RS07110	COG1006	Multisubunit Na H antiporter MnhC subunit
SD1155_RS07115	COG2111	Na H antiporter
SD1155_RS07135	COG1098	S1 RNA binding domain
SD1155_RS07140	COG1902	pentaerythritol trinitrate reductase activity
SD1155_RS07160	COG0584	glycerophosphoryl diester phosphodiesterase
SD1155_RS07165	COG0584	glycerophosphoryl diester phosphodiesterase
SD1155_RS07170	COG0165	Argininosuccinate lyase
SD1155_RS07175	COG0137	argininosuccinate synthase activity
SD1155_RS07185	COG0398	Pfam SNARE associated Golgi protein
SD1155_RS07210	COG1074	ATP-dependent DNA helicase activity
SD1155_RS07235	COG0561	phosphatase activity
SD1155_RS07250	COG0542	response to heat
SD1155_RS07260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SD1155_RS07275	COG0601	transmembrane transport
SD1155_RS07280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SD1155_RS07285	COG0444	Belongs to the ABC transporter superfamily
SD1155_RS07290	COG4608	Belongs to the ABC transporter superfamily
SD1155_RS07295	COG4166	transmembrane transport
SD1155_RS07300	COG0180	Tryptophanyl-tRNA synthetase
SD1155_RS07305	COG1393	Belongs to the ArsC family
SD1155_RS07310	COG4862	establishment of competence for transformation
SD1155_RS07320	COG1164	Oligoendopeptidase f
SD1155_RS07325	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SD1155_RS07330	COG2346	COG2346, Truncated hemoglobins
SD1155_RS07345	COG2357	RelA SpoT domain protein
SD1155_RS07350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SD1155_RS07355	COG0564	pseudouridine synthase activity
SD1155_RS07360	COG2239	Acts as a magnesium transporter
SD1155_RS07365	COG0569	domain protein
SD1155_RS07365	COG0475	glutathione-regulated potassium exporter activity
SD1155_RS07375	COG0628	permease
SD1155_RS07380	COG1115	amino acid carrier protein
SD1155_RS07385	COG2382	esterase
SD1155_RS07390	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SD1155_RS07395	COG2814	Major facilitator Superfamily
SD1155_RS07400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SD1155_RS07405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SD1155_RS07415	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SD1155_RS07425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SD1155_RS07430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SD1155_RS07445	COG4873	Protein conserved in bacteria
SD1155_RS07480	COG2314	TM2 domain
SD1155_RS07490	COG1575	Belongs to the MenA family. Type 1 subfamily
SD1155_RS07495	COG1169	isochorismate synthase
SD1155_RS07510	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SD1155_RS07515	COG0436	Aminotransferase
SD1155_RS07520	COG3594	Acyltransferase
SD1155_RS07545	COG1316	TRANSCRIPTIONal
SD1155_RS07560	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
SD1155_RS07575	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SD1155_RS07585	COG1017	nitric oxide dioxygenase activity
SD1155_RS07585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SD1155_RS07590	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SD1155_RS07595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SD1155_RS07605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SD1155_RS07610	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SD1155_RS07615	COG0047	phosphoribosylformylglycinamidine synthase activity
SD1155_RS07630	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SD1155_RS07640	COG0138	bifunctional purine biosynthesis protein purh
SD1155_RS07645	COG0151	Belongs to the GarS family
SD1155_RS07650	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SD1155_RS07655	COG4172	Belongs to the ABC transporter superfamily
SD1155_RS07680	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SD1155_RS07690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SD1155_RS07695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SD1155_RS07705	COG1271	oxidase subunit
SD1155_RS07710	COG1294	oxidase, subunit
SD1155_RS07715	COG0569	domain protein
SD1155_RS07720	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SD1155_RS07725	COG5503	Protein of unknown function (DUF1447)
SD1155_RS07730	COG0242	peptide deformylase activity
SD1155_RS07750	COG0508	dehydrogenase complex catalyzes the overall conversion of
SD1155_RS07760	COG4476	Belongs to the UPF0223 family
SD1155_RS07775	COG1176	ABC-type spermidine putrescine transport system, permease component I
SD1155_RS07780	COG1177	transmembrane transport
SD1155_RS07805	COG4493	Belongs to the UPF0637 family
SD1155_RS07810	COG0483	inositol monophosphate 1-phosphatase activity
SD1155_RS07820	COG1217	gtp-binding protein TYPA
SD1155_RS07825	COG4896	Protein conserved in bacteria
SD1155_RS07830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SD1155_RS07835	COG4838	Belongs to the UPF0358 family
SD1155_RS07840	COG0772	Belongs to the SEDS family
SD1155_RS07850	COG1612	heme a metabolic process
SD1155_RS07855	COG0109	protoheme IX farnesyltransferase activity
SD1155_RS07870	COG3679	Belongs to the UPF0342 family
SD1155_RS07890	COG0742	ribosomal rna small subunit methyltransferase
SD1155_RS07895	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SD1155_RS07910	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SD1155_RS07915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SD1155_RS07920	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SD1155_RS07925	COG0072	phenylalanine-tRNA ligase activity
SD1155_RS07925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SD1155_RS07930	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SD1155_RS07935	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
SD1155_RS07945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SD1155_RS07945	COG1796	DNA polymerase
SD1155_RS07950	COG1193	negative regulation of DNA recombination
SD1155_RS07955	COG3118	belongs to the thioredoxin family
SD1155_RS07960	COG0322	excinuclease ABC activity
SD1155_RS07965	COG2009	succinate dehydrogenase
SD1155_RS07970	COG1053	succinate dehydrogenase
SD1155_RS07975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SD1155_RS07985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SD1155_RS08030	COG1011	Hydrolase
SD1155_RS08040	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
SD1155_RS08050	COG0275	rRNA processing
SD1155_RS08055	COG4839	cell division protein FtsL
SD1155_RS08060	COG0768	penicillin binding
SD1155_RS08065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SD1155_RS08075	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SD1155_RS08080	COG0849	cell division
SD1155_RS08085	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SD1155_RS08090	COG1496	oxidoreductase activity
SD1155_RS08095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SD1155_RS08100	COG1799	cell septum assembly
SD1155_RS08105	COG0762	integral membrane protein
SD1155_RS08115	COG3599	regulation of cell shape
SD1155_RS08120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SD1155_RS08130	COG1388	LysM domain
SD1155_RS08130	COG3942	CHAP domain
SD1155_RS08140	COG0564	pseudouridine synthase activity
SD1155_RS08150	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SD1155_RS08155	COG2233	PERMEase
SD1155_RS08160	COG0540	Belongs to the ATCase OTCase family
SD1155_RS08165	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SD1155_RS08170	COG0505	Belongs to the CarA family
SD1155_RS08175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SD1155_RS08180	COG0284	orotidine-5'-phosphate decarboxylase activity
SD1155_RS08185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SD1155_RS08205	COG0194	GDP metabolic process
SD1155_RS08210	COG1758	RNA polymerase activity
SD1155_RS08215	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SD1155_RS08220	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SD1155_RS08235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SD1155_RS08240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SD1155_RS08240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SD1155_RS08245	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SD1155_RS08250	COG0631	protein serine/threonine phosphatase activity
SD1155_RS08265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SD1155_RS08275	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SD1155_RS08280	COG1302	Protein conserved in bacteria
SD1155_RS08285	COG1461	Dihydroxyacetone kinase
SD1155_RS08290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SD1155_RS08295	COG1349	DNA-binding transcription factor activity
SD1155_RS08300	COG0416	fatty acid biosynthetic process
SD1155_RS08320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SD1155_RS08325	COG0571	ribonuclease III activity
SD1155_RS08330	COG1196	nuclear chromosome segregation
SD1155_RS08335	COG0552	protein localization to endoplasmic reticulum
SD1155_RS08340	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SD1155_RS08345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SD1155_RS08350	COG0228	four-way junction DNA binding
SD1155_RS08355	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SD1155_RS08360	COG0336	Belongs to the RNA methyltransferase TrmD family
SD1155_RS08375	COG4485	Bacterial membrane protein, YfhO
SD1155_RS08385	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SD1155_RS08390	COG0045	succinate-CoA ligase (ADP-forming) activity
SD1155_RS08395	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SD1155_RS08400	COG0758	DNA mediated transformation
SD1155_RS08405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SD1155_RS08410	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SD1155_RS08415	COG4974	Belongs to the 'phage' integrase family
SD1155_RS08420	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SD1155_RS08435	COG0052	Belongs to the universal ribosomal protein uS2 family
SD1155_RS08440	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SD1155_RS08445	COG0528	UMP kinase activity
SD1155_RS08450	COG0233	cytoplasmic translational termination
SD1155_RS08455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SD1155_RS08460	COG4589	Belongs to the CDS family
SD1155_RS08470	COG0442	prolyl-tRNA aminoacylation
SD1155_RS08475	COG2176	DNA-directed DNA polymerase activity
SD1155_RS08480	COG0779	Required for maturation of 30S ribosomal subunits
SD1155_RS08485	COG0195	Participates in both transcription termination and antitermination
SD1155_RS08490	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SD1155_RS08495	COG1358	cellular component organization or biogenesis
SD1155_RS08500	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SD1155_RS08505	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SD1155_RS08510	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SD1155_RS08515	COG0196	riboflavin kinase activity
SD1155_RS08520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SD1155_RS08525	COG1185	polyribonucleotide nucleotidyltransferase activity
SD1155_RS08535	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SD1155_RS08545	COG2188	Transcriptional regulator
SD1155_RS08550	COG0612	Peptidase, M16
SD1155_RS08555	COG0612	Peptidase, M16
SD1155_RS08560	COG1028	Short-chain dehydrogenase reductase Sdr
SD1155_RS08580	COG1058	Belongs to the CinA family
SD1155_RS08580	COG1546	Belongs to the CinA family
SD1155_RS08585	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SD1155_RS08590	COG1418	mRNA catabolic process
SD1155_RS08600	COG1692	metallophosphoesterase
SD1155_RS08605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SD1155_RS08605	COG0674	pyruvate-flavodoxin oxidoreductase activity
SD1155_RS08610	COG1013	pyruvate-flavodoxin oxidoreductase activity
SD1155_RS08615	COG4195	phage-related replication protein
SD1155_RS08625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SD1155_RS08630	COG4550	Control of competence regulator ComK, YlbF/YmcA
SD1155_RS08645	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SD1155_RS08650	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SD1155_RS08655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SD1155_RS08665	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SD1155_RS08675	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SD1155_RS08680	COG1923	regulation of RNA biosynthetic process
SD1155_RS08685	COG0386	Belongs to the glutathione peroxidase family
SD1155_RS08690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SD1155_RS08695	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SD1155_RS08700	COG0789	Transcriptional regulator
SD1155_RS08755	COG4585	Histidine kinase
SD1155_RS08760	COG2197	response regulator
SD1155_RS08770	COG1525	nuclease
SD1155_RS08785	COG0527	aspartate kinase activity
SD1155_RS08790	COG0460	homoserine dehydrogenase
SD1155_RS08795	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SD1155_RS08800	COG0083	homoserine kinase activity
SD1155_RS08815	COG0833	amino acid
SD1155_RS08830	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SD1155_RS08855	COG4224	UPF0291 protein
SD1155_RS08870	COG3763	UPF0154 protein
SD1155_RS08880	COG4846	Membrane protein involved in cytochrome C biogenesis
SD1155_RS08895	COG1970	mechanosensitive ion channel activity
SD1155_RS08900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SD1155_RS08905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SD1155_RS08910	COG0824	Thioesterase
SD1155_RS08925	COG0187	DNA topoisomerase II activity
SD1155_RS08930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SD1155_RS08935	COG1115	amino acid carrier protein
SD1155_RS08940	COG3711	transcriptional antiterminator
SD1155_RS08945	COG0628	permease
SD1155_RS08950	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SD1155_RS08950	COG0392	lysyltransferase activity
SD1155_RS08965	COG1942	4-Oxalocrotonate Tautomerase
SD1155_RS08970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SD1155_RS08975	COG0287	Prephenate dehydrogenase
SD1155_RS08980	COG1363	Peptidase, m42
SD1155_RS08985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SD1155_RS08990	COG0512	Glutamine amidotransferase of anthranilate synthase
SD1155_RS09000	COG0134	indole-3-glycerol-phosphate synthase activity
SD1155_RS09020	COG2348	transferase activity, transferring amino-acyl groups
SD1155_RS09025	COG2348	transferase activity, transferring amino-acyl groups
SD1155_RS09030	COG0561	phosphatase activity
SD1155_RS09035	COG4607	ABC-type enterochelin transport system periplasmic component
SD1155_RS09075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SD1155_RS09080	COG0581	inorganic phosphate transmembrane transporter activity
SD1155_RS09085	COG0573	inorganic phosphate transmembrane transporter activity
SD1155_RS09090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SD1155_RS09095	COG2996	Protein conserved in bacteria
SD1155_RS09100	COG0488	(ABC) transporter
SD1155_RS09110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SD1155_RS09115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SD1155_RS09120	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SD1155_RS09130	COG1473	amidohydrolase
SD1155_RS09145	COG1278	Cold shock
SD1155_RS09155	COG1254	Belongs to the acylphosphatase family
SD1155_RS09165	COG3853	Toxic anion resistance protein (TelA)
SD1155_RS09170	COG1114	Component of the transport system for branched-chain amino acids
SD1155_RS09175	COG4548	von Willebrand factor, type A
SD1155_RS09180	COG0714	Associated with various cellular activities
SD1155_RS09205	COG1131	(ABC) transporter
SD1155_RS09210	COG0508	dehydrogenase complex catalyzes the overall conversion of
SD1155_RS09215	COG0567	Dehydrogenase, E1 component
SD1155_RS09220	COG5002	protein histidine kinase activity
SD1155_RS09225	COG0745	RESPONSE REGULATOR receiver
SD1155_RS09230	COG0671	phosphoesterase, PA-phosphatase related
SD1155_RS09245	COG0793	Belongs to the peptidase S41A family
SD1155_RS09255	COG2190	(PTS) system
SD1155_RS09260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SD1155_RS09290	COG1413	lyase activity
SD1155_RS09295	COG1413	lyase activity
SD1155_RS09305	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SD1155_RS09320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SD1155_RS09325	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SD1155_RS09335	COG0116	Belongs to the methyltransferase superfamily
SD1155_RS09345	COG3599	regulation of cell shape
SD1155_RS09360	COG3331	DNA recombination
SD1155_RS09365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SD1155_RS09365	COG4499	WXG100 protein secretion system (Wss), protein YukC
SD1155_RS09375	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SD1155_RS09380	COG3935	DnaD domain protein
SD1155_RS09385	COG0017	Asparaginyl-tRNA synthetase
SD1155_RS09390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SD1155_RS09390	COG1199	ATP-dependent helicase activity
SD1155_RS09395	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SD1155_RS09395	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SD1155_RS09400	COG0617	tRNA 3'-terminal CCA addition
SD1155_RS09405	COG0438	transferase activity, transferring glycosyl groups
SD1155_RS09410	COG1694	Mazg nucleotide pyrophosphohydrolase
SD1155_RS09415	COG2738	Putative neutral zinc metallopeptidase
SD1155_RS09420	COG4347	Protein of unknown function (DUF1405)
SD1155_RS09425	COG5582	Belongs to the UPF0302 family
SD1155_RS09435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SD1155_RS09440	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SD1155_RS09445	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SD1155_RS09460	COG2226	methyltransferase
SD1155_RS09475	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SD1155_RS09480	COG1160	GTP binding
SD1155_RS09485	COG0539	negative regulation of cytoplasmic translation
SD1155_RS09500	COG0492	ferredoxin-NADP+ reductase activity
SD1155_RS09510	COG0514	ATP-dependent DNA helicase (RecQ)
SD1155_RS09520	COG1141	Ferredoxin
SD1155_RS09535	COG0745	RESPONSE REGULATOR receiver
SD1155_RS09540	COG1187	pseudouridine synthase activity
SD1155_RS09545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SD1155_RS09550	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SD1155_RS09560	COG4974	Belongs to the 'phage' integrase family
SD1155_RS09565	COG0735	belongs to the Fur family
SD1155_RS09570	COG0494	nUDIX hydrolase
SD1155_RS09575	COG0667	Aldo Keto reductase
SD1155_RS09580	COG1028	Short-chain dehydrogenase reductase Sdr
SD1155_RS09585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SD1155_RS09595	COG1234	tRNA 3'-trailer cleavage
SD1155_RS09600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SD1155_RS09610	COG0366	Alpha amylase catalytic
SD1155_RS09615	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SD1155_RS09620	COG2195	Cleaves the N-terminal amino acid of tripeptides
SD1155_RS09625	COG4129	membrane
SD1155_RS09635	COG0508	dehydrogenase complex catalyzes the overall conversion of
SD1155_RS09640	COG0022	dehydrogenase e1 component
SD1155_RS09645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SD1155_RS09650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SD1155_RS09655	COG0497	DNA recombination
SD1155_RS09660	COG1438	arginine binding
SD1155_RS09670	COG1722	exodeoxyribonuclease VII activity
SD1155_RS09680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SD1155_RS09685	COG1302	Protein conserved in bacteria
SD1155_RS09690	COG0439	Biotin carboxylase
SD1155_RS09695	COG0511	ligase activity, forming carbon-carbon bonds
SD1155_RS09700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SD1155_RS09705	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SD1155_RS09710	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SD1155_RS09715	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SD1155_RS09720	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SD1155_RS09725	COG0006	proline dipeptidase activity
SD1155_RS09740	COG0095	Lipoate-protein ligase
SD1155_RS09745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SD1155_RS09760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SD1155_RS09765	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SD1155_RS09785	COG4537	Required for transformation and DNA binding
SD1155_RS09790	COG1459	type II secretion system
SD1155_RS09795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SD1155_RS09800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SD1155_RS09805	COG0011	TIGRFAM Protein of
SD1155_RS09810	COG1940	carbohydrate kinase activity
SD1155_RS09815	COG4483	Protein conserved in bacteria
SD1155_RS09825	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SD1155_RS09830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SD1155_RS09835	COG0768	penicillin binding
SD1155_RS09850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SD1155_RS09855	COG1121	(ABC) transporter
SD1155_RS09860	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SD1155_RS09865	COG0513	Belongs to the DEAD box helicase family
SD1155_RS09870	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SD1155_RS09875	COG2384	SAM-dependent methyltransferase
SD1155_RS09880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SD1155_RS09885	COG0358	DNA primase activity
SD1155_RS09890	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SD1155_RS09895	COG0517	IMP dehydrogenase activity
SD1155_RS09900	COG0423	glycine-tRNA ligase activity
SD1155_RS09905	COG1381	Involved in DNA repair and RecF pathway recombination
SD1155_RS09910	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SD1155_RS09930	COG1702	phosphate starvation-inducible protein PhoH
SD1155_RS09940	COG4864	UPF0365 protein
SD1155_RS09945	COG1030	water channel activity
SD1155_RS09955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SD1155_RS09960	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SD1155_RS09970	COG0484	heat shock protein binding
SD1155_RS09975	COG0443	Heat shock 70 kDa protein
SD1155_RS09980	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SD1155_RS09990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SD1155_RS09995	COG0481	GTPase activity
SD1155_RS10000	COG0268	Binds directly to 16S ribosomal RNA
SD1155_RS10005	COG1466	dna polymerase III delta subunit
SD1155_RS10010	COG0658	competence protein
SD1155_RS10010	COG2333	competence protein COMEC
SD1155_RS10015	COG2131	deaminase
SD1155_RS10020	COG1596	polysaccharide export
SD1155_RS10020	COG1555	photosystem II stabilization
SD1155_RS10030	COG0799	negative regulation of ribosome biogenesis
SD1155_RS10035	COG1713	HD superfamily hydrolase involved in NAD metabolism
SD1155_RS10040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SD1155_RS10045	COG1534	Rna-binding protein
SD1155_RS10050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SD1155_RS10055	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SD1155_RS10060	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SD1155_RS10065	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SD1155_RS10070	COG1914	H( )-stimulated, divalent metal cation uptake system
SD1155_RS10075	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SD1155_RS10080	COG0439	Biotin carboxylase
SD1155_RS10085	COG0511	ligase activity, forming carbon-carbon bonds
SD1155_RS10090	COG1984	allophanate hydrolase subunit 2
SD1155_RS10095	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SD1155_RS10100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SD1155_RS10105	COG0572	uridine kinase
SD1155_RS10110	COG0826	peptidase U32
SD1155_RS10115	COG0826	peptidase U32
SD1155_RS10120	COG4122	O-methyltransferase activity
SD1155_RS10125	COG3906	Belongs to the UPF0473 family
SD1155_RS10130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SD1155_RS10135	COG4472	Bacterial protein of unknown function (DUF965)
SD1155_RS10145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SD1155_RS10155	COG0482	sulfurtransferase activity
SD1155_RS10160	COG1104	cysteine desulfurase activity
SD1155_RS10165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SD1155_RS10175	COG1959	2 iron, 2 sulfur cluster binding
SD1155_RS10180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SD1155_RS10185	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SD1155_RS10205	COG0860	N-Acetylmuramoyl-L-alanine amidase
SD1155_RS10215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SD1155_RS10225	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SD1155_RS10225	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SD1155_RS10230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SD1155_RS10230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SD1155_RS10235	COG1862	Preprotein translocase
SD1155_RS10245	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SD1155_RS10255	COG0632	four-way junction helicase activity
SD1155_RS10260	COG4492	Belongs to the UPF0735 family
SD1155_RS10265	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SD1155_RS10270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SD1155_RS10275	COG2868	ribosomal protein
SD1155_RS10280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SD1155_RS10315	COG2003	Belongs to the UPF0758 family
SD1155_RS10325	COG0285	dihydrofolate synthase activity
SD1155_RS10335	COG2818	Glycosylase
SD1155_RS10345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SD1155_RS10350	COG0113	porphobilinogen synthase activity
SD1155_RS10360	COG0181	hydroxymethylbilane synthase activity
SD1155_RS10365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SD1155_RS10375	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SD1155_RS10380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SD1155_RS10385	COG0544	peptidyl-prolyl cis-trans isomerase activity
SD1155_RS10395	COG4112	unkown
SD1155_RS10400	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SD1155_RS10405	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SD1155_RS10410	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SD1155_RS10415	COG0833	amino acid
SD1155_RS10425	COG1484	DNA-dependent DNA replication
SD1155_RS10430	COG3611	Membrane attachment protein
SD1155_RS10435	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SD1155_RS10440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SD1155_RS10445	COG0237	dephospho-CoA kinase activity
SD1155_RS10450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SD1155_RS10455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SD1155_RS10455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SD1155_RS10460	COG5002	protein histidine kinase activity
SD1155_RS10465	COG0745	RESPONSE REGULATOR receiver
SD1155_RS10470	COG0538	isocitrate dehydrogenase activity
SD1155_RS10475	COG0372	Belongs to the citrate synthase family
SD1155_RS10480	COG1113	amino acid transport
SD1155_RS10485	COG0469	pyruvate kinase activity
SD1155_RS10490	COG0205	6-phosphofructokinase activity
SD1155_RS10500	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SD1155_RS10505	COG0281	malic enzyme
SD1155_RS10515	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SD1155_RS10520	COG4109	DRTGG domain
SD1155_RS10530	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SD1155_RS10535	COG0006	proline dipeptidase activity
SD1155_RS10540	COG0686	Belongs to the AlaDH PNT family
SD1155_RS10545	COG0589	response to stress
SD1155_RS10550	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SD1155_RS10555	COG0827	DNA restriction-modification system
SD1155_RS10560	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SD1155_RS10570	COG0301	tRNA thio-modification
SD1155_RS10575	COG1104	cysteine desulfurase activity
SD1155_RS10580	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SD1155_RS10585	COG1956	GAF domain-containing protein
SD1155_RS10595	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SD1155_RS10600	COG0584	glycerophosphoryl diester phosphodiesterase
SD1155_RS10605	COG1764	response to oxidative stress
SD1155_RS10610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SD1155_RS10615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SD1155_RS10625	COG1263	PTS System
SD1155_RS10625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SD1155_RS10645	COG0204	Acyl-transferase
SD1155_RS10650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SD1155_RS10655	COG2814	Major facilitator Superfamily
SD1155_RS10670	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SD1155_RS10680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SD1155_RS10685	COG0454	-acetyltransferase
SD1155_RS10695	COG1609	Transcriptional regulator
SD1155_RS10700	COG1605	Chorismate mutase
SD1155_RS10700	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SD1155_RS10715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SD1155_RS10720	COG1674	ftsk spoiiie
SD1155_RS10725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SD1155_RS10730	COG4848	Belongs to the UPF0354 family
SD1155_RS10735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SD1155_RS10750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SD1155_RS10755	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SD1155_RS10760	COG0510	thiamine kinase activity
SD1155_RS10765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SD1155_RS10770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SD1155_RS10780	COG1187	pseudouridine synthase activity
SD1155_RS10785	COG2244	polysaccharide biosynthetic process
SD1155_RS10790	COG2081	HI0933 family
SD1155_RS10805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SD1155_RS10810	COG0495	leucyl-tRNA aminoacylation
SD1155_RS10815	COG2814	Major facilitator Superfamily
SD1155_RS10820	COG1242	4 iron, 4 sulfur cluster binding
SD1155_RS10825	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SD1155_RS10835	COG2267	carboxylic ester hydrolase activity
SD1155_RS10840	COG0506	proline dehydrogenase activity
SD1155_RS10845	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SD1155_RS10850	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SD1155_RS10850	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SD1155_RS10855	COG0307	riboflavin synthase, alpha
SD1155_RS10860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SD1155_RS10860	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SD1155_RS10870	COG3266	domain, Protein
SD1155_RS10870	COG5632	N-Acetylmuramoyl-L-alanine amidase
SD1155_RS10870	COG4193	domain, Protein
SD1155_RS10895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SD1155_RS10910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SD1155_RS10915	COG0656	L-ascorbic acid biosynthetic process
SD1155_RS10925	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SD1155_RS10935	COG1506	peptidase
SD1155_RS10955	COG0318	PFAM AMP-dependent synthetase and ligase
SD1155_RS11005	COG3545	Serine hydrolase
SD1155_RS11010	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SD1155_RS11015	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SD1155_RS11025	COG2329	Antibiotic biosynthesis monooxygenase
SD1155_RS11030	COG4473	ABC transporter
SD1155_RS11035	COG1131	(ABC) transporter
SD1155_RS11040	COG0537	adenosine 5'-monophosphoramidase activity
SD1155_RS11055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SD1155_RS11065	COG3481	metal-dependent phosphohydrolase, HD sub domain
SD1155_RS11075	COG0420	3'-5' exonuclease activity
SD1155_RS11080	COG3679	Belongs to the UPF0342 family
SD1155_RS11085	COG4399	Belongs to the UPF0754 family
SD1155_RS11095	COG2197	response regulator
SD1155_RS11100	COG2203	Gaf domain
SD1155_RS11100	COG4585	Histidine kinase
SD1155_RS11105	COG0564	pseudouridine synthase activity
SD1155_RS11110	COG0114	fumarate hydratase activity
SD1155_RS11125	COG0363	glucosamine-6-phosphate deaminase activity
SD1155_RS11135	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SD1155_RS11140	COG1126	abc transporter atp-binding protein
SD1155_RS11145	COG0765	amino acid transport
SD1155_RS11310	COG0735	belongs to the Fur family
SD1155_RS11315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SD1155_RS11320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SD1155_RS11325	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SD1155_RS11330	COG4129	membrane
SD1155_RS11340	COG3557	Belongs to the UPF0374 family
SD1155_RS11345	COG1194	a g-specific adenine glycosylase
SD1155_RS11350	COG1988	membrane-bound metal-dependent
SD1155_RS11360	COG1134	teichoic acid transport
SD1155_RS11360	COG1388	LysM domain
SD1155_RS11375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SD1155_RS11380	COG0693	protein deglycase activity
SD1155_RS11390	COG0535	radical SAM domain protein
SD1155_RS11400	COG2309	aminopeptidase activity
SD1155_RS11405	COG4840	Belongs to the UPF0435 family
SD1155_RS11420	COG1295	ribonuclease BN
SD1155_RS11425	COG2197	response regulator
SD1155_RS11445	COG0024	Methionine aminopeptidase
SD1155_RS11450	COG4129	membrane
SD1155_RS11495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SD1155_RS11500	COG1597	lipid kinase activity
SD1155_RS11505	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SD1155_RS11520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SD1155_RS11530	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SD1155_RS11535	COG0210	DNA helicase
SD1155_RS11540	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
SD1155_RS11545	COG4496	protein, YerC YecD
SD1155_RS11550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SD1155_RS11560	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
SD1155_RS11565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SD1155_RS11570	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SD1155_RS11580	COG0077	Prephenate dehydratase
SD1155_RS11590	COG1335	isochorismatase
SD1155_RS11595	COG1227	inorganic diphosphatase activity
SD1155_RS11600	COG1012	belongs to the aldehyde dehydrogenase family
SD1155_RS11605	COG2706	6-phosphogluconolactonase activity
SD1155_RS11650	COG1131	(ABC) transporter
SD1155_RS11665	COG1725	Transcriptional regulator
SD1155_RS11805	COG0582	viral genome integration into host DNA
SD1155_RS11810	COG0459	protein refolding
SD1155_RS11815	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SD1155_RS11870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SD1155_RS11875	COG1621	beta-fructofuranosidase activity
SD1155_RS11880	COG1609	Transcriptional regulator
SD1155_RS11885	COG0425	Belongs to the sulfur carrier protein TusA family
SD1155_RS11890	COG2391	methyltransferase activity
SD1155_RS11905	COG0488	(ABC) transporter
SD1155_RS11910	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SD1155_RS11915	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SD1155_RS11920	COG0456	acetyltransferase
SD1155_RS11925	COG1214	PFAM Peptidase M22, glycoprotease
SD1155_RS11930	COG0802	atpase or kinase
SD1155_RS11935	COG0129	dihydroxy-acid dehydratase activity
SD1155_RS11940	COG0028	Belongs to the TPP enzyme family
SD1155_RS11960	COG0473	3-isopropylmalate dehydrogenase activity