locus-tag	class	description
G6548_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
G6548_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
G6548_RS00030	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
G6548_RS00040	ENOG4107JPU	
G6548_RS00050	ENOG4105C5Q	Transcriptional regulator
G6548_RS00060	ENOG4105E39	Enoyl-CoA hydratase
G6548_RS00100	ENOG4105EXG	Transcriptional regulator
G6548_RS00115	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
G6548_RS00120	ENOG4105CHF	Glutathione S-transferase
G6548_RS00125	ENOG4105EW9	transcriptional regulator AsnC family
G6548_RS00145	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
G6548_RS00160	ENOG4105F27	Major Facilitator
G6548_RS00170	ENOG4105CV8	reductase
G6548_RS00285	ENOG4105Y7M	Transcriptional regulator, TetR family
G6548_RS00290	ENOG4105EMU	Dehydrogenase
G6548_RS00295	ENOG4107QM5	aconitate hydratase
G6548_RS00360	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
G6548_RS00365	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
G6548_RS00380	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
G6548_RS00385	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G6548_RS00400	ENOG4105YK5	50S ribosomal protein L36
G6548_RS00405	ENOG4105CYM	Glutathione S-transferase
G6548_RS00415	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
G6548_RS00420	ENOG4105DZS	Phenylacetate-CoA ligase
G6548_RS00425	ENOG4108IV0	ABC, transporter
G6548_RS00440	ENOG4105C32	Amino acid ABC transporter (Permease)
G6548_RS00445	ENOG4105C0Z	ABC transporter
G6548_RS00460	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G6548_RS00480	ENOG4108IEG	Formate dehydrogenase Alpha subunit
G6548_RS00490	ENOG4108K3A	Glutathione S-transferase
G6548_RS00500	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
G6548_RS00545	ENOG4108Z2U	ureidoglycolate hydrolase
G6548_RS00550	ENOG4105S0E	allantoin catabolism protein
G6548_RS00565	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
G6548_RS00570	ENOG4105C26	Dehydrogenase
G6548_RS00590	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
G6548_RS00595	ENOG4105DC1	bifunctional purine biosynthesis protein purh
G6548_RS00605	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
G6548_RS00620	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
G6548_RS00625	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
G6548_RS00630	ENOG4108T58	Mg2 transport protein CorA
G6548_RS00635	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
G6548_RS00650	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
G6548_RS00660	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
G6548_RS00725	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
G6548_RS00730	ENOG4105QAX	Iron-sulfur
G6548_RS00745	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G6548_RS00760	ENOG4105D3R	alkyl hydroperoxide reductase
G6548_RS00770	ENOG4105D3G	Pseudouridine synthase
G6548_RS00795	ENOG4105CHU	acetyl-coa acetyltransferase
G6548_RS00800	ENOG4105WN5	stage II sporulation protein
G6548_RS00810	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
G6548_RS00840	ENOG4105CHM	Aminotransferase
G6548_RS00845	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
G6548_RS00865	ENOG4105K63	Thioredoxin
G6548_RS00870	ENOG4105CGK	Exodeoxyribonuclease III
G6548_RS00875	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G6548_RS00880	ENOG4107QJN	gtp cyclohydrolase ii
G6548_RS00890	ENOG4105DFA	alanine racemase domain protein
G6548_RS00905	ENOG4105C8T	Leucyl-tRNA synthetase
G6548_RS00920	ENOG4108K3A	Glutathione S-transferase
G6548_RS00945	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
G6548_RS00960	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
G6548_RS00965	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
G6548_RS00985	ENOG4105CEN	a g-specific adenine glycosylase
G6548_RS00990	ENOG4105EEF	Alkane 1-monooxygenase
G6548_RS01000	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G6548_RS01020	ENOG4105DIQ	Transcriptional regulator
G6548_RS01025	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
G6548_RS01035	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS01060	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
G6548_RS01070	ENOG41077A9	carbonic anhydrase
G6548_RS01080	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
G6548_RS01095	ENOG4108ZJI	phenylacetic acid degradation protein
G6548_RS01110	ENOG4105RK9	auxin efflux carrier
G6548_RS01115	ENOG4105C4W	S-formylglutathione hydrolase
G6548_RS01120	ENOG4108UPT	UPF0178 protein
G6548_RS01130	ENOG4105CIF	Ornithine Cyclodeaminase
G6548_RS01135	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
G6548_RS01145	ENOG4105D6Z	AFG1 family ATPase
G6548_RS01155	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
G6548_RS01160	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
G6548_RS01170	ENOG4108JJA	ABC, transporter
G6548_RS01175	ENOG4105C01	Dihydroxy-acid dehydratase
G6548_RS01200	ENOG4105CZN	Potassium uptake protein
G6548_RS01205	ENOG4105CN1	protease
G6548_RS01215	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G6548_RS01230	ENOG4105C2M	dna polymerase I
G6548_RS01235	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
G6548_RS01245	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G6548_RS01265	ENOG4105BZU	Histidine kinase
G6548_RS01270	ENOG4105D1Q	UPF0246 protein
G6548_RS01275	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G6548_RS01295	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
G6548_RS01310	ENOG4108YZN	class I peptide chain release factor
G6548_RS01320	ENOG4107RH7	Nicotinate phosphoribosyltransferase
G6548_RS01325	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
G6548_RS01330	ENOG4108RWI	nicotinamidase
G6548_RS01335	ENOG4105C72	UPF0176 protein
G6548_RS01340	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
G6548_RS01345	ENOG4105CJP	fad dependent oxidoreductase
G6548_RS01350	ENOG4105D38	putrescine abc transporter
G6548_RS01355	ENOG4105F38	ABC transporter, permease
G6548_RS01360	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G6548_RS01370	ENOG4108WYP	Transcriptional regulator
G6548_RS01375	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
G6548_RS01380	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G6548_RS01400	ENOG4105CVE	Lytic murein transglycosylase
G6548_RS01405	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
G6548_RS01420	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
G6548_RS01435	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
G6548_RS01450	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
G6548_RS01465	ENOG4105EAC	phosphoserine phosphatase
G6548_RS01470	ENOG4105CHU	acetyl-coa acetyltransferase
G6548_RS01475	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
G6548_RS01480	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
G6548_RS01485	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
G6548_RS01490	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
G6548_RS01495	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
G6548_RS01500	ENOG4105DXM	phenylacetic acid degradation protein
G6548_RS01515	ENOG4105C2X	Arabinose 5-phosphate isomerase
G6548_RS01530	ENOG4108IUZ	ABC transporter
G6548_RS01535	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
G6548_RS01540	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
G6548_RS01575	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
G6548_RS01580	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
G6548_RS01595	ENOG4105CFG	Acts as a chaperone (By similarity)
G6548_RS01600	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G6548_RS01605	ENOG4105W5Q	DNA repair protein (RadC
G6548_RS01635	ENOG4105DY2	Paraquat-inducible protein b
G6548_RS01640	ENOG4105F1S	paraquat-inducible protein a
G6548_RS01650	ENOG4108Z0Z	intracellular protease Pfpi family
G6548_RS01665	ENOG4105CXN	decarboxylase
G6548_RS01685	ENOG4105CBC	glutamate synthase
G6548_RS01690	ENOG4108JPW	Aminotransferase
G6548_RS01695	ENOG4108JCI	Transcriptional regulator
G6548_RS01720	ENOG41074H6	response regulator
G6548_RS01745	ENOG4107U9T	Pfam:Ribonuclease_BN
G6548_RS01750	ENOG4105S64	Formate nitrite transporter
G6548_RS01760	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
G6548_RS01765	ENOG4105CFG	Acts as a chaperone (By similarity)
G6548_RS01770	ENOG4105DEF	Extracellular solute-binding protein, family 5
G6548_RS01825	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G6548_RS01835	ENOG4105KXX	peptidase s58 dmpa
G6548_RS01840	ENOG4105KNK	cytochrome C
G6548_RS01870	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G6548_RS01875	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
G6548_RS01880	ENOG4105K9H	YciI-like protein
G6548_RS01895	ENOG4105CA0	peroxidase
G6548_RS01905	ENOG4105E2R	ROK family
G6548_RS01910	ENOG4105DFW	ABC transporter
G6548_RS01915	ENOG4108HWW	ABC transporter
G6548_RS01920	ENOG4105C2J	ABC transporter
G6548_RS01925	ENOG4105CMG	Carbohydrate kinase
G6548_RS01930	ENOG4105C93	Xylose Isomerase
G6548_RS01940	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
G6548_RS01950	ENOG4108R7K	Metal Dependent Phosphohydrolase
G6548_RS01960	ENOG4108UYB	regulatoR
G6548_RS01965	ENOG4108ZX6	Electron transport protein SCO1 SenC
G6548_RS01970	ENOG4105TX3	Histidine kinase
G6548_RS01975	ENOG4105I8F	Histidine kinase
G6548_RS01985	ENOG4105EHM	Aminoglycoside phosphotransferase
G6548_RS01990	ENOG4108S0S	Nucleotidyl transferase
G6548_RS02000	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
G6548_RS02005	ENOG4105K63	Thioredoxin
G6548_RS02015	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
G6548_RS02020	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
G6548_RS02050	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
G6548_RS02055	ENOG4107RZZ	dna polymerase iii epsilon subunit
G6548_RS02060	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
G6548_RS02070	ENOG4108UHJ	MAF-like protein
G6548_RS02075	ENOG4108YXA	Membrane
G6548_RS02080	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
G6548_RS02085	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
G6548_RS02090	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
G6548_RS02095	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
G6548_RS02110	ENOG4105CSA	Coproporphyrinogen iii oxidase
G6548_RS02115	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
G6548_RS02120	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
G6548_RS02130	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G6548_RS02135	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
G6548_RS02140	ENOG4105C6K	Malic enzyme
G6548_RS02145	ENOG4105D7K	pfkb domain protein
G6548_RS02150	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
G6548_RS02155	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G6548_RS02170	ENOG4105CDH	Citrulline--aspartate ligase
G6548_RS02175	ENOG4105C7B	Threonine dehydratase
G6548_RS02200	ENOG4105P8F	nudix hydrolase
G6548_RS02205	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
G6548_RS02210	ENOG4105BZ1	(ABC) transporter
G6548_RS02215	ENOG4105BZ1	(ABC) transporter
G6548_RS02230	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
G6548_RS02250	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
G6548_RS02260	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
G6548_RS02265	ENOG4105VW4	glutaredoxin 3
G6548_RS02280	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G6548_RS02295	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
G6548_RS02310	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
G6548_RS02325	ENOG4105M6F	mutator MutT protein
G6548_RS02330	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
G6548_RS02335	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
G6548_RS02340	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
G6548_RS02350	ENOG4105D3Q	Sugar transferase
G6548_RS02355	ENOG4105MEW	serine threonine protein phosphatase
G6548_RS02360	ENOG4105E3R	(LipO)protein
G6548_RS02370	ENOG4105DAY	polysaccharide export protein
G6548_RS02375	ENOG4105CKK	Glycosyl transferase, family 2
G6548_RS02450	ENOG4105EVB	acetyltransferase
G6548_RS02460	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
G6548_RS02470	ENOG4106D4I	domain protein
G6548_RS02520	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
G6548_RS02540	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
G6548_RS02550	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
G6548_RS02560	ENOG4107RFB	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
G6548_RS02570	ENOG4107RT3	EamA-like transporter family
G6548_RS02580	ENOG4105FYV	Amp nucleosidase
G6548_RS02585	ENOG4105CPN	adenine deaminase
G6548_RS02590	ENOG4107SBE	Glycosyl transferase (Group 1
G6548_RS02605	ENOG4107T0D	ABC, transporter
G6548_RS02610	ENOG4106SMU	thiamine transporter membrane protein
G6548_RS02615	ENOG4105DP9	ABC transporter
G6548_RS02620	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
G6548_RS02635	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G6548_RS02640	ENOG41090HR	transcriptional regulator
G6548_RS02645	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G6548_RS02650	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G6548_RS02655	ENOG4105CTB	Polyprenyl synthetase
G6548_RS02660	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
G6548_RS02675	ENOG4108U78	Glutathione S-transferase
G6548_RS02680	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
G6548_RS02685	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
G6548_RS02690	ENOG4105EIX	cytochrome c1
G6548_RS02700	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
G6548_RS02705	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
G6548_RS02715	ENOG4105E7W	lamb ycsf family protein
G6548_RS02725	ENOG4105P4J	Allophanate hydrolase, subunit 1
G6548_RS02730	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS02740	ENOG4105CH5	extracellular solute-binding protein, family 7
G6548_RS02745	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G6548_RS02750	ENOG4105T0Z	Conserved Protein
G6548_RS02755	ENOG4105DIQ	Transcriptional regulator
G6548_RS02800	ENOG4108IFG	nitrite reductase, (NAD(P)H)
G6548_RS02805	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
G6548_RS02815	ENOG4108I0Q	anthranilate phosphoribosyltransferase
G6548_RS02820	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
G6548_RS02830	ENOG4105E0K	tonB-dependent siderophore receptor
G6548_RS02835	ENOG4105J76	Periplasmic binding protein
G6548_RS02840	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
G6548_RS02845	ENOG4105E0A	ABC, transporter
G6548_RS02850	ENOG4105BZ1	(ABC) transporter
G6548_RS02855	ENOG4105DHQ	Histidine kinase
G6548_RS02870	ENOG4105DIJ	Phosphoethanolamine transferase
G6548_RS02880	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G6548_RS02895	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G6548_RS02900	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G6548_RS02905	ENOG4105EGS	Mechanosensitive ion channel
G6548_RS02915	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
G6548_RS02930	ENOG4105CQB	FAD linked oxidase domain protein
G6548_RS02935	ENOG4105EU8	FAD linked oxidase domain protein
G6548_RS02945	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
G6548_RS02960	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
G6548_RS02965	ENOG4105C26	Dehydrogenase
G6548_RS02990	ENOG4105RX8	Protein of unknown function (DUF1523)
G6548_RS02995	ENOG4105K59	histidine triad (HIT) protein
G6548_RS03010	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
G6548_RS03015	ENOG4105KHC	sulfurtransferase
G6548_RS03020	ENOG4105CGF	Aromatic amino acid aminotransferase
G6548_RS03030	ENOG4108YZA	Nitrogen regulatory protein pii
G6548_RS03035	ENOG4108JQC	penicillin-binding protein 1A
G6548_RS03045	ENOG4107653	Transcriptional regulator
G6548_RS03050	ENOG410903C	(LipO)protein
G6548_RS03060	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
G6548_RS03070	ENOG4105KZX	Pterin carbinolamine dehydratase
G6548_RS03085	ENOG4106H78	methyltransferase
G6548_RS03095	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
G6548_RS03100	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
G6548_RS03105	ENOG4105PW4	Sugar fermentation stimulation protein homolog
G6548_RS03110	ENOG4108I62	cina-like protein
G6548_RS03130	ENOG4105CC0	LysR family Transcriptional regulator
G6548_RS03140	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G6548_RS03145	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
G6548_RS03165	ENOG4105CSM	endonuclease III
G6548_RS03170	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
G6548_RS03175	ENOG4105UYK	outer membrane protein a
G6548_RS03185	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
G6548_RS03190	ENOG4108SXK	Transporter Drug Metabolite Exporter family
G6548_RS03195	ENOG4107SC1	transglycosylase
G6548_RS03200	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
G6548_RS03210	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
G6548_RS03230	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
G6548_RS03235	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
G6548_RS03240	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
G6548_RS03245	ENOG4105CQM	Urea amidohydrolase subunit alpha
G6548_RS03250	ENOG4105KI2	Urea amidohydrolase subunit beta
G6548_RS03260	ENOG4108YZ9	Urea amidohydrolase subunit gamma
G6548_RS03265	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
G6548_RS03270	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS03285	ENOG4106HBX	Transcriptional Regulator AraC Family
G6548_RS03300	ENOG4108WUH	Transcriptional regulator, TetR family
G6548_RS03330	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
G6548_RS03340	ENOG4105CI0	Citrate lyase
G6548_RS03350	ENOG4107S8C	mandelate racemase muconate lactonizing
G6548_RS03365	ENOG4105CA9	Pyruvate kinase
G6548_RS03375	ENOG41082BR	50S ribosomal protein L35
G6548_RS03380	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
G6548_RS03390	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
G6548_RS03405	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
G6548_RS03410	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
G6548_RS03415	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
G6548_RS03420	ENOG4105DCF	alanine dehydrogenase
G6548_RS03425	ENOG4108YXU	transcriptional regulator AsnC family
G6548_RS03435	ENOG4105K5G	30S ribosomal protein S21
G6548_RS03445	ENOG4108JJB	ABC transporter
G6548_RS03450	ENOG4107YZB	Cobalt transport protein
G6548_RS03460	ENOG4105BZU	Histidine kinase
G6548_RS03470	ENOG4105WH1	Two component transcriptional regulator luxr family
G6548_RS03490	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
G6548_RS03495	ENOG4105C9M	aspartyl-trna synthetase
G6548_RS03510	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
G6548_RS03530	ENOG41069NU	Nitroreductase
G6548_RS03535	ENOG4105DGU	Histone deacetylase
G6548_RS03540	ENOG4105C31	Tryptophanyl-tRNA synthetase
G6548_RS03550	ENOG4105CJR	Integral membrane protein (MviN
G6548_RS03555	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
G6548_RS03565	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
G6548_RS03575	ENOG4105D7Z	glutathione synthase
G6548_RS03585	ENOG4105C0P	Mg chelatase subunit ChlI
G6548_RS03610	ENOG4105D5T	phosphonate abc transporter
G6548_RS03615	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
G6548_RS03620	ENOG4105S7S	phosphonate abc transporter
G6548_RS03645	ENOG4105KZ6	phosphonate C-P lyase system protein PhnH
G6548_RS03660	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
G6548_RS03665	ENOG4105HRV	phosphonate c-p lyase system protein phnl
G6548_RS03675	ENOG4105FD8	phosphonate metabolism protein PhnM
G6548_RS03680	ENOG4105D06	uba thif-type nad fad binding protein
G6548_RS03685	ENOG4105DGW	oligopeptidase A
G6548_RS03690	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
G6548_RS03695	ENOG4105CNI	cell division protein FtsW
G6548_RS03700	ENOG4105CJN	penicillin-binding protein
G6548_RS03710	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
G6548_RS03730	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G6548_RS03740	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
G6548_RS03750	ENOG4105C4K	Nad synthetase
G6548_RS03755	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
G6548_RS03770	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
G6548_RS03775	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
G6548_RS03780	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6548_RS03785	ENOG4105ECY	inositol monophosphatase
G6548_RS03790	ENOG4105CV6	ABC transporter, permease
G6548_RS03795	ENOG4108I0Y	(ABC) transporter
G6548_RS03800	ENOG4108UJV	acyl-CoA thioesterase i
G6548_RS03810	ENOG4105BZ8	glutamate synthase
G6548_RS03815	ENOG4107SJI	Dehydrogenase
G6548_RS03820	ENOG4108R86	Transcriptional regulator
G6548_RS03825	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
G6548_RS03830	ENOG4105CD3	dihydroorotase
G6548_RS03840	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
G6548_RS03845	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
G6548_RS03850	ENOG4107Z6I	Thiamine biosynthesis protein
G6548_RS03855	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
G6548_RS03865	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G6548_RS03870	ENOG4105C5H	ABC transporter
G6548_RS03880	ENOG4105BZG	amino acid carrier protein
G6548_RS03885	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
G6548_RS03895	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
G6548_RS03905	ENOG4105DK7	lysyl-tRNA synthetase
G6548_RS03915	ENOG4107MV2	Inherit from COG: Hemolysin-type calcium-binding
G6548_RS03945	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
G6548_RS03965	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
G6548_RS03970	ENOG4105EM7	Selenocysteine-specific translation elongation factor
G6548_RS03995	ENOG4105CE4	GlcNAc 6-P deacetylase
G6548_RS04000	ENOG4105RD7	BadF BadG BcrA BcrD
G6548_RS04005	ENOG4105C01	Dihydroxy-acid dehydratase
G6548_RS04010	ENOG4108UHU	Aldolase
G6548_RS04030	ENOG4107ZT5	Thiol disulfide interchange protein
G6548_RS04035	ENOG4105CH7	arginosuccinase
G6548_RS04050	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
G6548_RS04065	ENOG4105CAK	Cell division ATP-binding protein ftsE
G6548_RS04080	ENOG4107QN2	dihydrolipoyl dehydrogenase
G6548_RS04095	ENOG4105C7S	Dehydrogenase
G6548_RS04120	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
G6548_RS04125	ENOG4105DJG	MaoC domain protein dehydratase
G6548_RS04155	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
G6548_RS04160	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
G6548_RS04165	ENOG4105PDA	succinate dehydrogenase, hydrophobic membrane anchor protein
G6548_RS04170	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
G6548_RS04185	ENOG4105E33	succinate dehydrogenase
G6548_RS04200	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
G6548_RS04205	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
G6548_RS04215	ENOG4105E55	glycerol-3-phosphate acyltransferase
G6548_RS04225	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
G6548_RS04245	ENOG4105UIB	(ABC) transporter
G6548_RS04250	ENOG4108JQ9	ABC transporter
G6548_RS04255	ENOG4105DIH	basic membrane
G6548_RS04260	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
G6548_RS04265	ENOG41072GX	Peptidase M22 Glycoprotease
G6548_RS04270	ENOG41083MR	nifu domain-containing protein
G6548_RS04280	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G6548_RS04300	ENOG4108UT2	hemolysin iii
G6548_RS04310	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
G6548_RS04320	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
G6548_RS04345	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
G6548_RS04350	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
G6548_RS04360	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
G6548_RS04370	ENOG4105C3G	gtp-binding protein
G6548_RS04380	ENOG4105EMU	Dehydrogenase
G6548_RS04385	ENOG4105E9Z	Nad-dependent epimerase dehydratase
G6548_RS04405	ENOG4105E0X	reductase
G6548_RS04415	ENOG4105CQ7	ATP-dependent helicase
G6548_RS04420	ENOG4105DJT	lAO AO transport system ATPase
G6548_RS04435	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
G6548_RS04440	ENOG4105C25	Primosomal protein n'
G6548_RS04470	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
G6548_RS04475	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
G6548_RS04485	ENOG4107YD3	Thioesterase
G6548_RS04490	ENOG4105E02	MotA TolQ exbB proton channel
G6548_RS04495	ENOG4105M8F	Biopolymer transport protein exbD tolR
G6548_RS04505	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
G6548_RS04510	ENOG4105KCK	Peptidoglycan-associated lipoprotein
G6548_RS04520	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
G6548_RS04525	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G6548_RS04535	ENOG4105CKU	formyltetrahydrofolate synthetase
G6548_RS04540	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
G6548_RS04555	ENOG4107QRT	dEAD DEAH box helicase
G6548_RS04620	ENOG4105E4C	Lytic transglycosylase catalytic
G6548_RS04625	ENOG4107QNJ	CoA-transferase subunit B
G6548_RS04645	ENOG4105C79	DNA protecting protein DprA
G6548_RS04650	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
G6548_RS04655	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
G6548_RS04660	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
G6548_RS04670	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
G6548_RS04675	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
G6548_RS04685	ENOG4105D98	threonine synthase
G6548_RS04710	ENOG4105C8Y	Acetylornithine aminotransferase
G6548_RS04715	ENOG4105DBV	ornithine carbamoyltransferase
G6548_RS04725	ENOG4105CJ3	phosphate transporter
G6548_RS04735	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
G6548_RS04740	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
G6548_RS04745	ENOG4105CM6	amino acid regulated cytosolic protein
G6548_RS04755	ENOG4106K28	UPF0283 membrane protein
G6548_RS04760	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
G6548_RS04770	ENOG4105VE1	Phosphatidylcholine synthase
G6548_RS04775	ENOG4105KDC	50s ribosomal protein l28
G6548_RS04790	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
G6548_RS04795	ENOG4105DND	Transcriptional regulator
G6548_RS04800	ENOG4105ES4	Nitrilase
G6548_RS04810	ENOG4108Z03	MAF-like protein
G6548_RS04960	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G6548_RS04965	ENOG4105BZS	acriflavin resistance protein
G6548_RS04990	ENOG4105ECR	NmrA family
G6548_RS05005	ENOG4105JQN	Transcriptional regulator
G6548_RS05015	ENOG4105CC0	LysR family Transcriptional regulator
G6548_RS05030	ENOG4107EFR	Flavocytochrome c
G6548_RS05035	ENOG4105DRR	Transcriptional regulator, GntR family
G6548_RS05045	ENOG4108JQ1	Dehydrogenase
G6548_RS05060	ENOG4105C7F	AcnD-accessory protein PrpF
G6548_RS05080	ENOG41062D9	Histidine kinase
G6548_RS05090	ENOG4105EJC	lysr family transcriptional regulator
G6548_RS05095	ENOG410830R	acetyltransferase
G6548_RS05100	ENOG4105C3M	thioredoxin reductase
G6548_RS05110	ENOG4108JA1	polyketide synthase
G6548_RS05115	ENOG4105E39	Enoyl-CoA hydratase
G6548_RS05120	ENOG4107RUY	(E1 component), alpha subunit
G6548_RS05125	ENOG4105CPP	Dehydrogenase, E1 component
G6548_RS05135	ENOG4105C7S	Dehydrogenase
G6548_RS05140	ENOG4108KMH	lipoate-protein ligase a
G6548_RS05150	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G6548_RS05180	ENOG4105DG4	malate L-lactate dehydrogenase
G6548_RS05200	ENOG4105C32	Amino acid ABC transporter (Permease)
G6548_RS05205	ENOG4105CNN	ABC, transporter
G6548_RS05210	ENOG4105C0Z	ABC transporter
G6548_RS05215	ENOG4108IV0	ABC, transporter
G6548_RS05220	ENOG4105BZU	Histidine kinase
G6548_RS05230	ENOG4108QY0	Membrane
G6548_RS05245	ENOG4108ZZF	transport protein (ExbD)
G6548_RS05255	ENOG4107E2E	PKHD-type hydroxylase
G6548_RS05260	ENOG4108ESX	Receptor
G6548_RS05275	ENOG4105C94	Transporter
G6548_RS05285	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
G6548_RS05305	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
G6548_RS05320	ENOG4108ZTZ	UPF0262 protein
G6548_RS05340	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
G6548_RS05355	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G6548_RS05365	ENOG4107T8Q	Glycosyl transferase (Group 1
G6548_RS05375	ENOG4105D8X	mechanosensitive ion channel
G6548_RS05380	ENOG4107T8T	UPF0173 metal-dependent hydrolase
G6548_RS05385	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G6548_RS05390	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
G6548_RS05400	ENOG4108JQ5	ABC transporter
G6548_RS05420	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS05430	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G6548_RS05435	ENOG4105X7H	acyl-CoA dehydrogenase
G6548_RS05440	ENOG4105C1G	acyl-Coa dehydrogenase
G6548_RS05450	ENOG4105CGU	Enoyl-CoA hydratase
G6548_RS05455	ENOG4105CEY	Amp-dependent synthetase and ligase
G6548_RS05460	ENOG4105DJV	ribulose-phosphate 3-epimerase
G6548_RS05475	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
G6548_RS05490	ENOG41080HT	Transcriptional regulator, arsr family
G6548_RS05500	ENOG4107QIV	Cytochrome c biogenesis protein
G6548_RS05530	ENOG4105CGH	5'-nucleotidase
G6548_RS05560	ENOG4105CEY	Amp-dependent synthetase and ligase
G6548_RS05570	ENOG4105D8X	mechanosensitive ion channel
G6548_RS05580	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
G6548_RS05590	ENOG4105DJ9	glucan biosynthesis protein
G6548_RS05595	ENOG4105DFD	Na H antiporter
G6548_RS05600	ENOG4105CEY	Amp-dependent synthetase and ligase
G6548_RS05605	ENOG4105C8Y	Acetylornithine aminotransferase
G6548_RS05610	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
G6548_RS05615	ENOG4105ENR	peptidase, M24
G6548_RS05635	ENOG4105BZU	Histidine kinase
G6548_RS05670	ENOG4105C7W	Xanthine dehydrogenase
G6548_RS05675	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
G6548_RS05680	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
G6548_RS05685	ENOG4105ETT	transcriptional Regulator, LysR family
G6548_RS05690	ENOG4105CHR	reductase
G6548_RS05765	ENOG4105CQB	FAD linked oxidase domain protein
G6548_RS05780	ENOG4108UQ1	hydrolase, family 25
G6548_RS05790	ENOG4105FC8	fad dependent oxidoreductase
G6548_RS05820	ENOG4105UIB	(ABC) transporter
G6548_RS05825	ENOG4108JQ9	ABC transporter
G6548_RS05835	ENOG4105C7W	Xanthine dehydrogenase
G6548_RS05855	ENOG4105CUT	histidyl-tRNA synthetase
G6548_RS05860	ENOG4105P5X	ATP phosphoribosyltransferase regulatory subunit
G6548_RS05865	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
G6548_RS05885	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
G6548_RS05895	ENOG4105EXG	Transcriptional regulator
G6548_RS05910	ENOG4105D6J	arsenicaL-resistance protein
G6548_RS05920	ENOG4105CAU	Arsenical resistance protein, ArsH
G6548_RS05930	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
G6548_RS05965	ENOG4105DRS	transport system, permease
G6548_RS05975	ENOG4105C01	Dihydroxy-acid dehydratase
G6548_RS05980	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
G6548_RS05985	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
G6548_RS05990	ENOG4108RTU	Aldolase
G6548_RS05995	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
G6548_RS06005	ENOG4105D01	(LipO)protein
G6548_RS06010	ENOG4108UMI	ABC transporter, permease
G6548_RS06015	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
G6548_RS06030	ENOG4108YXU	transcriptional regulator AsnC family
G6548_RS06040	ENOG4105CGF	Aromatic amino acid aminotransferase
G6548_RS06050	ENOG4105EG6	Saccharopine dehydrogenase
G6548_RS06060	ENOG4105HDK	L-asparaginase
G6548_RS06070	ENOG4105K7W	phage-related replication protein
G6548_RS06085	ENOG4108MEK	Metal-binding protein YodA
G6548_RS06090	ENOG4105CH5	extracellular solute-binding protein, family 7
G6548_RS06100	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS06105	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
G6548_RS06135	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
G6548_RS06145	ENOG4105DUM	transcriptional regulator, lysR family
G6548_RS06175	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
G6548_RS06200	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
G6548_RS06205	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
G6548_RS06220	ENOG4105CVE	Lytic murein transglycosylase
G6548_RS06225	ENOG4105C5Q	Transcriptional regulator
G6548_RS06230	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
G6548_RS06270	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
G6548_RS06275	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
G6548_RS06280	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
G6548_RS06285	ENOG4107QPD	alcohol dehydrogenase
G6548_RS06290	ENOG4108XHQ	(2Fe-2S)-binding domain protein
G6548_RS06295	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
G6548_RS06305	ENOG4105CEY	Amp-dependent synthetase and ligase
G6548_RS06315	ENOG4105BZ1	(ABC) transporter
G6548_RS06320	ENOG4109066	lysm domain bon superfamily protein
G6548_RS06325	ENOG4105CEY	Amp-dependent synthetase and ligase
G6548_RS06340	ENOG4108JQ6	ABC transporter
G6548_RS06345	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G6548_RS06385	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
G6548_RS06430	ENOG4105FE9	pseudouridine synthase
G6548_RS06435	ENOG4108Z6B	deaminase
G6548_RS06450	ENOG4107T8T	UPF0173 metal-dependent hydrolase
G6548_RS06455	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G6548_RS06460	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
G6548_RS06480	ENOG4105W0E	50S ribosomal protein L33
G6548_RS06490	ENOG4105HFZ	Membrane
G6548_RS06495	ENOG4108WRK	Transcriptional regulator
G6548_RS06500	ENOG4105ECY	inositol monophosphatase
G6548_RS06505	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
G6548_RS06515	ENOG4107QUY	Guanine deaminase
G6548_RS06520	ENOG4105CJW	magnesium transporter
G6548_RS06525	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
G6548_RS06530	ENOG4105D48	metallophosphoesterase
G6548_RS06545	ENOG4105CDY	transcriptional regulatory protein
G6548_RS06565	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
G6548_RS06570	ENOG4105CBG	Sulfatase
G6548_RS06595	ENOG4105CFF	transcriptional regulator
G6548_RS06600	ENOG4105CZQ	inner membrane transport protein YdhC
G6548_RS06660	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
G6548_RS06675	ENOG4107R33	ppx gppa phosphatase
G6548_RS06680	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
G6548_RS06690	ENOG4105C02	permease
G6548_RS06700	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
G6548_RS06715	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G6548_RS06745	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G6548_RS06750	ENOG4108MYF	
G6548_RS06765	ENOG4107QI1	Mate efflux family protein
G6548_RS06805	ENOG4107XDR	Lactoylglutathione lyase
G6548_RS06820	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
G6548_RS06840	ENOG4105KUZ	arsenate reductase
G6548_RS06855	ENOG4105E18	UPF0276 protein
G6548_RS06865	ENOG4105C22	threonyL-tRNA synthetase
G6548_RS06905	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
G6548_RS06920	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G6548_RS06925	ENOG4105CJP	fad dependent oxidoreductase
G6548_RS06930	ENOG4105CFQ	glutamine synthetase
G6548_RS06935	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G6548_RS06940	ENOG4105CFQ	glutamine synthetase
G6548_RS06945	ENOG4105E5Q	amino acid AbC transporter
G6548_RS06950	ENOG4105GBT	ABC transporter
G6548_RS06960	ENOG4108JEH	abc transporter atp-binding protein
G6548_RS06980	ENOG4105D6S	protein involved in catabolism of external DNA
G6548_RS06985	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
G6548_RS07000	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
G6548_RS07035	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G6548_RS07045	ENOG4105BZU	Histidine kinase
G6548_RS07055	ENOG4105C3Q	Glycosyl transferase, family 2
G6548_RS07070	ENOG4105DEF	Extracellular solute-binding protein, family 5
G6548_RS07080	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
G6548_RS07085	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G6548_RS07090	ENOG4105C3U	ABC transporter
G6548_RS07095	ENOG4108JQ7	(ABC) transporter
G6548_RS07115	ENOG4108IJ7	Glycine betaine
G6548_RS07125	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
G6548_RS07130	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
G6548_RS07135	ENOG4105CH6	catalase
G6548_RS07145	ENOG4105EHG	Permease protein
G6548_RS07160	ENOG4105EMU	Dehydrogenase
G6548_RS07165	ENOG4105UEI	Transcriptional Regulator AraC Family
G6548_RS07180	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
G6548_RS07185	ENOG4105D6E	homoserine dehydrogenase
G6548_RS07205	ENOG4105EJQ	L-serine dehydratase
G6548_RS07210	ENOG4105CYM	Glutathione S-transferase
G6548_RS07215	ENOG4105E66	phosphoriboisomerase A
G6548_RS07225	ENOG4107QJR	hflk protein
G6548_RS07230	ENOG4105EPW	hflc protein
G6548_RS07235	ENOG4105C0H	protease
G6548_RS07255	ENOG4105DIK	(ABC) transporter
G6548_RS07260	ENOG4105CC5	ABC transporter
G6548_RS07265	ENOG4105CC5	ABC transporter
G6548_RS07280	ENOG4105E98	transcriptional regulator DeoR family
G6548_RS07285	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
G6548_RS07290	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G6548_RS07295	ENOG4108IJ9	(ABC) transporter
G6548_RS07305	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
G6548_RS07320	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
G6548_RS07325	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G6548_RS07330	ENOG4105C0A	alcohol dehydrogenase
G6548_RS07335	ENOG4105HF0	Membrane
G6548_RS07340	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G6548_RS07355	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
G6548_RS07360	ENOG4106FI7	cytochrome c-type biogenesis protein
G6548_RS07365	ENOG4105DDR	sarcosine oxidase (Beta subunit)
G6548_RS07380	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
G6548_RS07390	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G6548_RS07405	ENOG4108URH	decarboxylase
G6548_RS07415	ENOG4108JJ7	ABC transporter
G6548_RS07425	ENOG4105C2C	drug resistance transporter, Bcr CflA
G6548_RS07430	ENOG4105BZS	acriflavin resistance protein
G6548_RS07450	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
G6548_RS07460	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
G6548_RS07465	ENOG4105VIE	preprotein translocase, subunit YajC
G6548_RS07470	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G6548_RS07475	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G6548_RS07480	ENOG4108UIV	Protein of unknown function (DUF498/DUF598)
G6548_RS07485	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
G6548_RS07490	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
G6548_RS07495	ENOG41060IM	Heme exporter protein
G6548_RS07505	ENOG4107QX9	Thiol disulfide interChange protein
G6548_RS07525	ENOG4105C5F	glutamine synthetase
G6548_RS07530	ENOG4108YZA	Nitrogen regulatory protein pii
G6548_RS07535	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
G6548_RS07540	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
G6548_RS07570	ENOG4107YM4	Beta-lactamase domain-containing protein
G6548_RS07575	ENOG4105F8V	Hydrolase, tatD family
G6548_RS07580	ENOG4107QRG	dna polymerase iii
G6548_RS07585	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
G6548_RS07590	ENOG4105DZ1	carboxypeptidase
G6548_RS07840	ENOG4105BZU	Histidine kinase
G6548_RS07845	ENOG4105E98	transcriptional regulator DeoR family
G6548_RS07860	ENOG4105S7S	phosphonate abc transporter
G6548_RS07870	ENOG4105PAD	Hydrolase
G6548_RS07900	ENOG4105YHG	TonB family
G6548_RS07910	ENOG4105BZU	Histidine kinase
G6548_RS07915	ENOG4105FAV	ABC, transporter
G6548_RS07920	ENOG4105FDK	ABC transporter
G6548_RS07950	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G6548_RS07955	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
G6548_RS07975	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
G6548_RS07980	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
G6548_RS07985	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
G6548_RS07990	ENOG4108IV0	ABC, transporter
G6548_RS07995	ENOG4105C0Z	ABC transporter
G6548_RS08005	ENOG4105C32	Amino acid ABC transporter (Permease)
G6548_RS08015	ENOG4105CFF	transcriptional regulator
G6548_RS08020	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G6548_RS08055	ENOG4105Y2X	UPF0335 protein
G6548_RS08060	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
G6548_RS08075	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
G6548_RS08080	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
G6548_RS08085	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
G6548_RS08095	ENOG4108YYC	ycei family
G6548_RS08100	ENOG4105DS1	cytochrome b561
G6548_RS08105	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
G6548_RS08115	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
G6548_RS08125	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
G6548_RS08130	ENOG4105HHA	aminodeoxychorismate lyase
G6548_RS08220	ENOG4105D7W	serine acetyltransferase
G6548_RS08225	ENOG4105C7S	Dehydrogenase
G6548_RS08230	ENOG4105CPP	Dehydrogenase, E1 component
G6548_RS08235	ENOG4108JYK	Dehydrogenase
G6548_RS08245	ENOG4105BZA	Phosphoglycerate kinase
G6548_RS08265	ENOG4105DR5	peptidase
G6548_RS08270	ENOG4105ED9	Protein of unknown function (DUF455)
G6548_RS08275	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G6548_RS08285	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
G6548_RS08290	ENOG4105D2S	major facilitator superfamily
G6548_RS08300	ENOG4107QN2	dihydrolipoyl dehydrogenase
G6548_RS08305	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G6548_RS08330	ENOG4105C26	Dehydrogenase
G6548_RS08345	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
G6548_RS08350	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
G6548_RS08360	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
G6548_RS08365	ENOG4105CKW	Inner membrane protein yedI
G6548_RS08375	ENOG4105CV1	Transketolase (EC 2.2.1.1)
G6548_RS08410	ENOG4107XAN	XdhC and CoxI family
G6548_RS08435	ENOG4105KCK	Peptidoglycan-associated lipoprotein
G6548_RS08440	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
G6548_RS08450	ENOG4105DP0	ferredoxin-NADP reductase
G6548_RS08460	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
G6548_RS08465	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
G6548_RS08475	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
G6548_RS08480	ENOG4108XM1	transcriptional regulator AsnC family
G6548_RS08490	ENOG4105CQZ	Histidine kinase
G6548_RS08495	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G6548_RS08500	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
G6548_RS08505	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
G6548_RS08510	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS08515	ENOG4105CP7	Triose-phosphate isomerase
G6548_RS08520	ENOG4108Z4V	iron-sulfur cluster assembly
G6548_RS08530	ENOG4105VG1	fes assembly suf system protein
G6548_RS08535	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
G6548_RS08540	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
G6548_RS08545	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G6548_RS08550	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
G6548_RS08555	ENOG4105K70	DNA-binding protein
G6548_RS08565	ENOG4105E9F	Enoyl-CoA hydratase
G6548_RS08570	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
G6548_RS08575	ENOG4105D7T	ABC transporter
G6548_RS08580	ENOG4105ETU	transcriptional activator (TenA
G6548_RS08585	ENOG4107Z6I	Thiamine biosynthesis protein
G6548_RS08590	ENOG4105D06	uba thif-type nad fad binding protein
G6548_RS08600	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
G6548_RS08635	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
G6548_RS08650	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
G6548_RS08655	ENOG4105VKD	bioY protein
G6548_RS08665	ENOG4105D7X	high-affinity nickel-transporter
G6548_RS08675	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
G6548_RS08680	ENOG4108IJ8	ABC transporter
G6548_RS08685	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
G6548_RS08690	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
G6548_RS08695	ENOG41066YJ	Beta-lactamase
G6548_RS08700	ENOG4105CH2	amidohydrolase
G6548_RS08720	ENOG4108VWS	Yaeq family
G6548_RS08745	ENOG4105E0F	Histidine kinase
G6548_RS08770	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
G6548_RS08785	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
G6548_RS08790	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
G6548_RS08800	ENOG4105CI3	gtp-binding protein typa
G6548_RS08805	ENOG4105D64	Mechanosensitive ion channel
G6548_RS08810	ENOG410814C	multidrug resistance protein
G6548_RS08835	ENOG4105DHZ	alpha beta
G6548_RS08840	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
G6548_RS08845	ENOG4105C3J	Cysteine desulfurase
G6548_RS08865	ENOG4105C3K	feS assembly ATPase SufC
G6548_RS08870	ENOG4105JRK	feS assembly protein SufD
G6548_RS08885	ENOG4105C9B	Cysteine desulfurase
G6548_RS08895	ENOG4105BZU	Histidine kinase
G6548_RS08905	ENOG4105DAE	Methylenetetrahydrofolate reductase
G6548_RS08915	ENOG4105C9X	ppx gppa phosphatase
G6548_RS08920	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
G6548_RS08925	ENOG4105D65	subunit l
G6548_RS08930	ENOG4108ZE9	Monovalent cation H antiporter subunit C
G6548_RS08935	ENOG4107R4Z	monovalent cation h antiporter subunit d
G6548_RS08940	ENOG4105SC1	monovalent cation H antiporter subunit E
G6548_RS08945	ENOG4105W4C	monovalent cation H antiporter subunit F
G6548_RS08950	ENOG4105KJM	monovalent cation h antiporter subunit g
G6548_RS08965	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
G6548_RS08970	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
G6548_RS08980	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
G6548_RS09010	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
G6548_RS09020	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
G6548_RS09025	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
G6548_RS09040	ENOG4108ZP8	Acetolactate synthase small subunit
G6548_RS09045	ENOG4105C7K	acetolactate synthase
G6548_RS09060	ENOG4105CH5	extracellular solute-binding protein, family 7
G6548_RS09075	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
G6548_RS09090	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
G6548_RS09105	ENOG4105DR4	Methyltransferase
G6548_RS09120	ENOG4108Z9K	Osmotically inducible protein
G6548_RS09150	ENOG4105MSY	salicylate hydroxylase
G6548_RS09160	ENOG41066UZ	arginase EC 3.5.3.1
G6548_RS09175	ENOG4108UM1	dedA family
G6548_RS09190	ENOG4105DEI	Mannitol dehydrogenase
G6548_RS09195	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G6548_RS09215	ENOG4105ETE	Transcriptional regulator (LacI family
G6548_RS09240	ENOG4108JU6	CBS domain protein
G6548_RS09250	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G6548_RS09265	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
G6548_RS09270	ENOG4105D49	3-dehydroquinate synthase
G6548_RS09275	ENOG4108UUM	single-stranded DNA-binding protein
G6548_RS09280	ENOG4105E4C	Lytic transglycosylase catalytic
G6548_RS09290	ENOG4108JQ6	ABC transporter
G6548_RS09295	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G6548_RS09310	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
G6548_RS09315	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
G6548_RS09320	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
G6548_RS09325	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
G6548_RS09335	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
G6548_RS09340	ENOG4105DZP	Membrane-associated zinc metalloprotease
G6548_RS09345	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6548_RS09355	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
G6548_RS09360	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G6548_RS09365	ENOG4105GYT	Protein of unknown function (DUF1009)
G6548_RS09370	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G6548_RS09375	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
G6548_RS09390	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
G6548_RS09395	ENOG4105CB5	ATP-dependent DNA helicase recG
G6548_RS09405	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
G6548_RS09410	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
G6548_RS09415	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
G6548_RS09435	ENOG4107SQD	Transcriptional regulator, GntR family
G6548_RS09440	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
G6548_RS09445	ENOG4108UJD	30S ribosomal protein S9
G6548_RS09450	ENOG4105DEN	Luciferase family
G6548_RS09455	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
G6548_RS09460	ENOG4105CSR	polyphosphate kinase 2
G6548_RS09465	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
G6548_RS09470	ENOG4105CVG	Homoserine O-transsuccinylase
G6548_RS09485	ENOG4108EHX	EamA-like transporter family
G6548_RS09490	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G6548_RS09495	ENOG4105F5V	trimethylamine methyltransferase
G6548_RS09510	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
G6548_RS09520	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
G6548_RS09525	ENOG4108Z1B	Cyclase dehydrase
G6548_RS09530	ENOG4105BZU	Histidine kinase
G6548_RS09540	ENOG4108ZAI	phosphatidylglycerophosphatase a
G6548_RS09545	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
G6548_RS09550	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G6548_RS09555	ENOG4105CUX	Signal transduction histidine kinase
G6548_RS09565	ENOG4105ES5	Histidine kinase
G6548_RS09570	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G6548_RS09580	ENOG4105C1A	potassium transporter peripheral membrane
G6548_RS09585	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
G6548_RS09590	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
G6548_RS09595	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
G6548_RS09605	ENOG4108R99	pseudouridine synthase
G6548_RS09615	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G6548_RS09625	ENOG4105D52	delta-aminolevulinic acid dehydratase
G6548_RS09645	ENOG4105CNG	UPF0061 protein
G6548_RS09655	ENOG4105DU0	nucleoside hydrolase
G6548_RS09660	ENOG4105DXN	mazG family
G6548_RS09670	ENOG4105CYW	agmatinase
G6548_RS09685	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
G6548_RS09690	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
G6548_RS09700	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
G6548_RS09705	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
G6548_RS09710	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G6548_RS09715	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
G6548_RS09730	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
G6548_RS09740	ENOG4108WIW	Aspartyl protease
G6548_RS09745	ENOG41081FY	multiple antibiotic resistance (MarC)-related
G6548_RS09750	ENOG4105C5H	ABC transporter
G6548_RS09755	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
G6548_RS09780	ENOG4105EAB	amino acid AbC transporter
G6548_RS09785	ENOG4105E5Q	amino acid AbC transporter
G6548_RS09790	ENOG4105CDA	abc transporter atp-binding protein
G6548_RS09800	ENOG4107RUE	extracellular solute-binding protein family 1
G6548_RS09805	ENOG4105F38	ABC transporter, permease
G6548_RS09810	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G6548_RS09820	ENOG4108K79	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G6548_RS09915	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
G6548_RS09920	ENOG4105K46	50S ribosomal protein l27
G6548_RS09940	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G6548_RS09945	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
G6548_RS09950	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
G6548_RS09975	ENOG4105CE9	30S ribosomal protein S2
G6548_RS09980	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
G6548_RS09985	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
G6548_RS09995	ENOG4105ERH	Fumarylacetoacetate hydrolase
G6548_RS10000	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G6548_RS10010	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
G6548_RS10020	ENOG4105C8U	phosphate abc transporter
G6548_RS10030	ENOG4105BZU	Histidine kinase
G6548_RS10035	ENOG4108Z0R	Transferase
G6548_RS10040	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
G6548_RS10045	ENOG4105DSJ	YicC domain protein
G6548_RS10055	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
G6548_RS10060	ENOG4105ECQ	AraC Family Transcriptional Regulator
G6548_RS10075	ENOG4105C0Z	ABC transporter
G6548_RS10085	ENOG4108IV0	ABC, transporter
G6548_RS10095	ENOG4105C32	Amino acid ABC transporter (Permease)
G6548_RS10105	ENOG4105D7A	ATP-binding protein
G6548_RS10125	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G6548_RS10140	ENOG4105W39	Membrane
G6548_RS10150	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
G6548_RS10155	ENOG4105EGS	Mechanosensitive ion channel
G6548_RS10165	ENOG41087AY	ADP-Ribose pyrophosphatase
G6548_RS10175	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
G6548_RS10180	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
G6548_RS10185	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
G6548_RS10215	ENOG4105C9Q	fumarate hydratase class II
G6548_RS10245	ENOG4107QIV	Cytochrome c biogenesis protein
G6548_RS10250	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
G6548_RS10255	ENOG4105C03	ribonuclease
G6548_RS10265	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G6548_RS10270	ENOG4105CQZ	Histidine kinase
G6548_RS10275	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
G6548_RS10280	ENOG410839H	phosphoribosylformylglycinamidine synthase
G6548_RS10285	ENOG4107QPR	SAICAR synthetase
G6548_RS10300	ENOG4108Q52	Methyltransferase cognate corrinoid protein
G6548_RS10310	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
G6548_RS10320	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
G6548_RS10325	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
G6548_RS10330	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
G6548_RS10340	ENOG4105BZU	Histidine kinase
G6548_RS10345	ENOG4105C26	Dehydrogenase
G6548_RS10350	ENOG4105F1G	UPF0441 protein
G6548_RS10355	ENOG4106032	Glutathionylspermidine synthase
G6548_RS10370	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
G6548_RS10375	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
G6548_RS10380	ENOG4107SPB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
G6548_RS10385	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
G6548_RS10390	ENOG4105CEY	Amp-dependent synthetase and ligase
G6548_RS10405	ENOG4107QP8	phosphohexose isomerase
G6548_RS10410	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
G6548_RS10415	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
G6548_RS10440	ENOG4105CTD	carboxy-peptidase
G6548_RS10445	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
G6548_RS10455	ENOG4105DWF	phosphomethylpyrimidine kinase
G6548_RS10470	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
G6548_RS10475	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
G6548_RS10495	ENOG4105E43	Extracellular solute-binding protein, family 5
G6548_RS10520	ENOG4105C2C	drug resistance transporter, Bcr CflA
G6548_RS10525	ENOG4105C1J	atp-dependent rna helicase
G6548_RS10540	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
G6548_RS10550	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
G6548_RS10555	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
G6548_RS10560	ENOG4105C5H	ABC transporter
G6548_RS10580	ENOG41082GS	50S ribosomal protein L32
G6548_RS10585	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
G6548_RS10590	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
G6548_RS10595	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G6548_RS10600	ENOG4105WJX	transcriptional regulator MERR family
G6548_RS10620	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
G6548_RS10625	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
G6548_RS10630	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
G6548_RS10640	ENOG4105C75	arginyL-tRNA synthetase
G6548_RS10645	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
G6548_RS10650	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
G6548_RS10690	ENOG4105DXI	Major Facilitator superfamily
G6548_RS10705	ENOG4105C8N	cysteinyl-tRNA synthetase
G6548_RS10710	ENOG4105CHM	Aminotransferase
G6548_RS10720	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
G6548_RS10735	ENOG4108YXU	transcriptional regulator AsnC family
G6548_RS10740	ENOG4107RTZ	reductase
G6548_RS10755	ENOG4105VEQ	Cold shock protein
G6548_RS10760	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
G6548_RS10765	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
G6548_RS10770	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
G6548_RS10775	ENOG4105CHM	Aminotransferase
G6548_RS10785	ENOG4105CRQ	synthase (Component I)
G6548_RS10800	ENOG4105DDQ	anthranilate synthase
G6548_RS10805	ENOG4108I0Q	anthranilate phosphoribosyltransferase
G6548_RS10810	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
G6548_RS10815	ENOG4105DK0	Indole-3-glycerol phosphate synthase
G6548_RS10820	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G6548_RS10825	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
G6548_RS10830	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
G6548_RS10835	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
G6548_RS10840	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
G6548_RS10845	ENOG4105BZN	citrate synthase
G6548_RS10855	ENOG4105CGU	Enoyl-CoA hydratase
G6548_RS10860	ENOG4105KWW	Biogenesis protein
G6548_RS10865	ENOG4105DA4	cytochrome c-type biogenesis protein
G6548_RS10880	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
G6548_RS10885	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
G6548_RS10890	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
G6548_RS10905	ENOG4105ETT	transcriptional Regulator, LysR family
G6548_RS10910	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
G6548_RS10920	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
G6548_RS10930	ENOG4105EKE	dihydroorotase
G6548_RS10935	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
G6548_RS10940	ENOG4105CDU	Replicative dna helicase
G6548_RS10955	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
G6548_RS10980	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
G6548_RS10990	ENOG4105EMU	Dehydrogenase
G6548_RS10995	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
G6548_RS11000	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
G6548_RS11015	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
G6548_RS11020	ENOG41081BE	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
G6548_RS11025	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
G6548_RS11035	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G6548_RS11070	ENOG4105C1J	atp-dependent rna helicase
G6548_RS11080	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
G6548_RS11085	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
G6548_RS11090	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G6548_RS11095	ENOG4105C8S	subunit m
G6548_RS11100	ENOG4105D65	subunit l
G6548_RS11105	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G6548_RS11110	ENOG4105DF2	NADH dehydrogenase subunit j
G6548_RS11115	ENOG4108048	decarboxylase
G6548_RS11120	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G6548_RS11125	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
G6548_RS11135	ENOG4107R0R	NADH dehydrogenase subunit g
G6548_RS11155	ENOG4107QIZ	NADH dehydrogenase
G6548_RS11165	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
G6548_RS11170	ENOG4105GKE	subunit e
G6548_RS11175	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G6548_RS11185	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6548_RS11190	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G6548_RS11195	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6548_RS11200	ENOG4105CMR	udp-glucose 4-epimerase
G6548_RS11205	ENOG4108UKI	Enoyl-CoA hydratase
G6548_RS11210	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
G6548_RS11225	ENOG4107QX3	carboxylase
G6548_RS11240	ENOG4105C1G	acyl-Coa dehydrogenase
G6548_RS11250	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
G6548_RS11260	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G6548_RS11265	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
G6548_RS11285	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G6548_RS11290	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
G6548_RS11295	ENOG4105CPK	Glycosyl transferase (Group 1
G6548_RS11300	ENOG4105CH2	amidohydrolase
G6548_RS11305	ENOG4105CH2	amidohydrolase
G6548_RS11310	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G6548_RS11315	ENOG4105CWC	Acetylornithine deacetylase
G6548_RS11320	ENOG4108JQ6	ABC transporter
G6548_RS11335	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G6548_RS11350	ENOG4107QPB	Beta-lactamase domain protein
G6548_RS11355	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G6548_RS11360	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G6548_RS11365	ENOG4105DTD	Dehydrogenase
G6548_RS11385	ENOG4107QP3	malate synthase g
G6548_RS11400	ENOG4105CD8	aminopeptidase N
G6548_RS11420	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G6548_RS11440	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G6548_RS11455	ENOG4105DC7	peptidase M24
G6548_RS11480	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6548_RS11485	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G6548_RS11490	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
G6548_RS11495	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
G6548_RS11500	ENOG4108UFP	Essential cell division protein (By similarity)
G6548_RS11505	ENOG4105CPF	Cell wall formation (By similarity)
G6548_RS11510	ENOG4105D4A	Cell wall formation (By similarity)
G6548_RS11530	ENOG4105DFU	Cell wall formation (By similarity)
G6548_RS11535	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
G6548_RS11550	ENOG4105CBX	hi0933 family
G6548_RS11560	ENOG4105DXI	Major Facilitator superfamily
G6548_RS11595	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
G6548_RS11600	ENOG4105CSV	Glutaminase
G6548_RS11605	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
G6548_RS11615	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
G6548_RS11630	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
G6548_RS11635	ENOG4107YZH	Cell division protein mraZ
G6548_RS11640	ENOG4105D1F	ATP-binding protein
G6548_RS11655	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
G6548_RS11660	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
G6548_RS11670	ENOG4105KTH	gatB Yqey
G6548_RS11675	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
G6548_RS11685	ENOG4105DRR	Transcriptional regulator, GntR family
G6548_RS11695	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
G6548_RS11705	ENOG4108XM1	transcriptional regulator AsnC family
G6548_RS11715	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
G6548_RS11725	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
G6548_RS11745	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
G6548_RS11750	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
G6548_RS11760	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
G6548_RS11770	ENOG4105C7K	acetolactate synthase
G6548_RS11775	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
G6548_RS11785	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
G6548_RS11795	ENOG4107835	probably involved in intracellular septation (By similarity)
G6548_RS11805	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
G6548_RS11815	ENOG4107QIZ	NADH dehydrogenase
G6548_RS11820	ENOG4105EEF	Alkane 1-monooxygenase
G6548_RS11830	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G6548_RS11845	ENOG4107Z7P	Ferredoxin
G6548_RS11855	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
G6548_RS11860	ENOG4105EHG	Permease protein
G6548_RS11865	ENOG4105DSF	transport protein
G6548_RS11870	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS11885	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G6548_RS11905	ENOG4105CFU	surface antigen
G6548_RS11910	ENOG4107QM5	aconitate hydratase
G6548_RS11930	ENOG4105C83	adenylosuccinate lyase
G6548_RS11950	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
G6548_RS11985	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
G6548_RS11990	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
G6548_RS12005	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
G6548_RS12010	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
G6548_RS12015	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
G6548_RS12020	ENOG4105K4P	CoA-binding domain protein
G6548_RS12060	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
G6548_RS12065	ENOG4105EW9	transcriptional regulator AsnC family
G6548_RS12070	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G6548_RS12075	ENOG4108VJ1	Transcriptional regulator (CarD family
G6548_RS12080	ENOG4108Z4U	Ferredoxin
G6548_RS12085	ENOG4105VEJ	Heat shock protein
G6548_RS12105	ENOG4108EUD	Lysophospholipase
G6548_RS12115	ENOG4107T0X	DNA ligase
G6548_RS12125	ENOG4105KSC	Transcriptional regulator, TraR DksA family
G6548_RS12175	ENOG4107XZX	Involved in the transcription termination process (By similarity)
G6548_RS12180	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
G6548_RS12185	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
G6548_RS12200	ENOG41084CK	capsule polysaccharide
G6548_RS12210	ENOG4105E12	capsule polysaccharide
G6548_RS12215	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
G6548_RS12220	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
G6548_RS12225	ENOG4105EMU	Dehydrogenase
G6548_RS12245	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G6548_RS12250	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
G6548_RS12295	ENOG4105DU6	RNA polymerase
G6548_RS12320	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
G6548_RS12330	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
G6548_RS12335	ENOG4105CPC	Aldo Keto reductase
G6548_RS12345	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
G6548_RS12350	ENOG4105BZU	Histidine kinase
G6548_RS12360	ENOG4105EW9	transcriptional regulator AsnC family
G6548_RS12380	ENOG4105ECY	inositol monophosphatase
G6548_RS12385	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
G6548_RS12400	ENOG4105DZ2	Transcriptional regulator
G6548_RS12405	ENOG4105SYT	Methylenetetrahydrofolate reductase
G6548_RS12420	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
G6548_RS12430	ENOG4105CIH	Imidazole acetol-phosphate transaminase
G6548_RS12445	ENOG4105BZ1	(ABC) transporter
G6548_RS12455	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
G6548_RS12460	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
G6548_RS12485	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
G6548_RS12505	ENOG4108I1J	Integrase
G6548_RS12575	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
G6548_RS12585	ENOG4105C0A	alcohol dehydrogenase
G6548_RS12590	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
G6548_RS12595	ENOG4105CFH	Aspartokinase
G6548_RS12610	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
G6548_RS12615	ENOG4105E0C	molybdate abc transporter
G6548_RS12620	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
G6548_RS12640	ENOG4105CHH	sulfate transporter
G6548_RS12645	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
G6548_RS12650	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
G6548_RS12675	ENOG4105PGM	cation diffusion facilitator family transporter
G6548_RS12690	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
G6548_RS12695	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
G6548_RS12705	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G6548_RS12710	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
G6548_RS12720	ENOG4105CAT	Cytidine monophosphate kinase
G6548_RS12725	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
G6548_RS12735	ENOG4105C94	Transporter
G6548_RS12740	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
G6548_RS12745	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
G6548_RS12750	ENOG4107RCQ	(CBS) domain
G6548_RS12760	ENOG4105C9A	Phoh family
G6548_RS12770	ENOG4105UYK	outer membrane protein a
G6548_RS12775	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
G6548_RS12790	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
G6548_RS12795	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
G6548_RS12800	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
G6548_RS12805	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
G6548_RS12810	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
G6548_RS12830	ENOG4105F2Z	3-oxoadipate enol-lactonase
G6548_RS12840	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
G6548_RS12855	ENOG4105CXK	mandelate racemase muconate lactonizing
G6548_RS12860	ENOG4105C1G	acyl-Coa dehydrogenase
G6548_RS12865	ENOG4105ETT	transcriptional Regulator, LysR family
G6548_RS12875	ENOG4105CGH	5'-nucleotidase
G6548_RS12895	ENOG4107R73	Mate efflux family protein
G6548_RS12920	ENOG4105WH1	Two component transcriptional regulator luxr family
G6548_RS12925	ENOG4108Z6Z	Transcriptional regulator
G6548_RS12930	ENOG4105CSU	acyl-Coa dehydrogenase
G6548_RS12940	ENOG4108K3A	Glutathione S-transferase
G6548_RS12945	ENOG4105CHU	acetyl-coa acetyltransferase
G6548_RS12965	ENOG4105CEY	Amp-dependent synthetase and ligase
G6548_RS12985	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
G6548_RS12990	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
G6548_RS12995	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
G6548_RS13005	ENOG4105C6K	Malic enzyme
G6548_RS13015	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G6548_RS13020	ENOG4105VDW	Csbd family
G6548_RS13025	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
G6548_RS13030	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
G6548_RS13040	ENOG4105EV9	Alpha Beta Hydrolase
G6548_RS13045	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
G6548_RS13055	ENOG4107104	thymidine kinase
G6548_RS13065	ENOG4108Z7R	Chaperone CsaA
G6548_RS13070	ENOG4105II7	pyrroline-5-carboxylate reductase
G6548_RS13085	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
G6548_RS13095	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
G6548_RS13110	ENOG4105F7P	transcriptional regulator AsnC family
G6548_RS13115	ENOG4105C3M	thioredoxin reductase
G6548_RS13120	ENOG4107RIQ	Sulfate adenylate transferase
G6548_RS13130	ENOG4108ZNX	Heat shock protein
G6548_RS13145	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
G6548_RS13150	ENOG4105FD8	phosphonate metabolism protein PhnM
G6548_RS13170	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
G6548_RS13175	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
G6548_RS13185	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
G6548_RS13205	ENOG4108Z7G	MaoC domain protein dehydratase
G6548_RS13210	ENOG4105DTN	riboflavin biosynthesis protein ribF
G6548_RS13215	ENOG4108ZZ3	UPF0260 protein
G6548_RS13220	ENOG4105C5W	Aldolase
G6548_RS13245	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
G6548_RS13250	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
G6548_RS13255	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
G6548_RS13260	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
G6548_RS13265	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G6548_RS13275	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
G6548_RS13290	ENOG4105UYK	outer membrane protein a
G6548_RS13300	ENOG4108NH8	Cation transport protein
G6548_RS13320	ENOG4105CIH	Imidazole acetol-phosphate transaminase
G6548_RS13325	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
G6548_RS13330	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G6548_RS13335	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G6548_RS13340	ENOG4105BZU	Histidine kinase
G6548_RS13360	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
G6548_RS13370	ENOG4105EAH	synthase
G6548_RS13375	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
G6548_RS13380	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
G6548_RS13385	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
G6548_RS13390	ENOG4108Z4X	TRANSCRIPTIONal
G6548_RS13400	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
G6548_RS13410	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
G6548_RS13420	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
G6548_RS13460	ENOG4105CSU	acyl-Coa dehydrogenase
G6548_RS13465	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G6548_RS13470	ENOG4108UJU	UPF0301 protein
G6548_RS13480	ENOG4105BZS	acriflavin resistance protein
G6548_RS13490	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
G6548_RS13495	ENOG410829K	Lysine exporter protein (Lyse ygga)
G6548_RS13500	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
G6548_RS13505	ENOG4105CXT	aspartate transcarbamylase
G6548_RS13530	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
G6548_RS13550	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
G6548_RS13555	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
G6548_RS13560	ENOG4108ZG0	Ompa motb domain protein
G6548_RS13570	ENOG4108ZAF	Molybdopterin
G6548_RS13580	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
G6548_RS13585	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
G6548_RS13590	ENOG4105CHR	reductase
G6548_RS13605	ENOG4105E3A	(ABC) transporter
G6548_RS13610	ENOG4105DA5	(ABC) transporter
G6548_RS13630	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
G6548_RS13635	ENOG4105C4M	(Ubiquinol oxidase) subunit I
G6548_RS13640	ENOG4107ZY3	Histidine kinase
G6548_RS13665	ENOG4105C5F	glutamine synthetase
G6548_RS13675	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS13690	ENOG4105HX0	Transcriptional regulator
G6548_RS13695	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
G6548_RS13710	ENOG41065SU	Two-component system sensor kinase
G6548_RS13715	ENOG4107QN2	dihydrolipoyl dehydrogenase
G6548_RS13725	ENOG4105VG0	50S ribosomal protein l34
G6548_RS13730	ENOG4105KK3	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
G6548_RS13735	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
G6548_RS13740	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
G6548_RS13750	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
G6548_RS13760	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
G6548_RS13765	ENOG4105CAS	nag kinase
G6548_RS13775	ENOG4105CDA	abc transporter atp-binding protein
G6548_RS13780	ENOG4105DRP	amino acid AbC transporter
G6548_RS13785	ENOG4105EZ7	amino acid ABC transporter
G6548_RS13790	ENOG4107QXX	ABC transporter
G6548_RS13800	ENOG4105EI2	Pseudouridine synthase
G6548_RS13805	ENOG41082CG	Protein CrcB homolog
G6548_RS13810	ENOG4105D1H	recombination factor protein RarA
G6548_RS13815	ENOG4105C0H	protease
G6548_RS13820	ENOG4108ZT0	50S ribosomal protein l17
G6548_RS13825	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G6548_RS13830	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
G6548_RS13835	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G6548_RS13840	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
G6548_RS13850	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
G6548_RS13855	ENOG41084HQ	50S ribosomal protein L30
G6548_RS13860	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
G6548_RS13865	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
G6548_RS13870	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
G6548_RS13875	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
G6548_RS13880	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
G6548_RS13885	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G6548_RS13890	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
G6548_RS13895	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
G6548_RS13900	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
G6548_RS13905	ENOG41083MP	50s ribosomal protein l29
G6548_RS13925	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
G6548_RS13930	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
G6548_RS13935	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
G6548_RS13940	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
G6548_RS13945	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G6548_RS13955	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
G6548_RS13960	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
G6548_RS13965	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
G6548_RS13970	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
G6548_RS13975	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G6548_RS13980	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
G6548_RS13985	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
G6548_RS13990	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
G6548_RS14000	ENOG4105DFI	Membrane
G6548_RS14005	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G6548_RS14010	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G6548_RS14015	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
G6548_RS14020	ENOG4108VZM	50s ribosomal protein L10
G6548_RS14025	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
G6548_RS14030	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
G6548_RS14035	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
G6548_RS14050	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G6548_RS14075	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G6548_RS14085	ENOG4105E1F	short-chain dehydrogenase reductase
G6548_RS14095	ENOG4108WBT	adenosyltransferase
G6548_RS14100	ENOG4105TPV	
G6548_RS14115	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G6548_RS14125	ENOG41080Z8	PHOSPHOCARRIER protein
G6548_RS14135	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
G6548_RS14145	ENOG4105EB3	Histidine kinase
G6548_RS14150	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
G6548_RS14155	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
G6548_RS14180	ENOG4105C1G	acyl-Coa dehydrogenase
G6548_RS14190	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
G6548_RS14200	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
G6548_RS14205	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
G6548_RS14210	ENOG4105C3F	Signal peptidase i
G6548_RS14215	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
G6548_RS14220	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
G6548_RS14230	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G6548_RS14235	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
G6548_RS14250	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
G6548_RS14260	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G6548_RS14265	ENOG4105EN6	Membrane
G6548_RS14275	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
G6548_RS14280	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G6548_RS14285	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G6548_RS14290	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G6548_RS14295	ENOG4105C87	Aminotransferase class I and II
G6548_RS14305	ENOG4105CHF	Glutathione S-transferase
G6548_RS14325	ENOG4105N5Q	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
G6548_RS14330	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G6548_RS14335	ENOG4105VD1	ATP synthase subunit C
G6548_RS14340	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
G6548_RS14365	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
G6548_RS14380	ENOG4105K5M	30s ribosomal protein S16
G6548_RS14390	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
G6548_RS14395	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
G6548_RS14400	ENOG4105C8V	SAICAR synthetase
G6548_RS14405	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
G6548_RS14410	ENOG41082FS	50S ribosomal protein L31
G6548_RS14420	ENOG4105D1F	ATP-binding protein
G6548_RS14430	ENOG4105ERH	Fumarylacetoacetate hydrolase
G6548_RS14440	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS14460	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
G6548_RS14465	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
G6548_RS14475	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
G6548_RS14480	ENOG4105CHR	reductase
G6548_RS14485	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
G6548_RS14490	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
G6548_RS14500	ENOG4105DZ1	carboxypeptidase
G6548_RS14505	ENOG4108JQ5	ABC transporter
G6548_RS14510	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
G6548_RS14515	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
G6548_RS14525	ENOG4105G9V	cytochrome C
G6548_RS14530	ENOG4105CQC	Prephenate dehydratase
G6548_RS14540	ENOG4105E09	nadh pyrophosphatase
G6548_RS14550	ENOG4105CGZ	zinc metallopeptidase
G6548_RS14560	ENOG4107QMP	dna polymerase iii subunits gamma and tau
G6548_RS14570	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
G6548_RS14575	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
G6548_RS14590	ENOG4105E9K	Isocitrate dehydrogenase
G6548_RS14605	ENOG4105C30	Nad-dependent epimerase dehydratase
G6548_RS14615	ENOG4107ZYJ	bioY protein
G6548_RS14620	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G6548_RS14660	ENOG4105QUC	reductase
G6548_RS14675	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
G6548_RS14680	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G6548_RS14685	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
G6548_RS14715	ENOG4107R51	Glycosyl transferase, family 2
G6548_RS14720	ENOG4105D3Q	Sugar transferase
G6548_RS14730	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
G6548_RS14735	ENOG4108JQ1	Dehydrogenase
G6548_RS14740	ENOG4105CPQ	Dehydrogenase
G6548_RS14745	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
G6548_RS14750	ENOG4108JCI	Transcriptional regulator
G6548_RS14755	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
G6548_RS14760	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G6548_RS14765	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
G6548_RS14770	ENOG4105E39	Enoyl-CoA hydratase
G6548_RS14775	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
G6548_RS14795	ENOG4107W75	Flagellin
G6548_RS14810	ENOG4108ZC9	flagellar basal-body rod protein flgc
G6548_RS14815	ENOG4105X50	flagellar hook-basal body complex protein fliE
G6548_RS14830	ENOG4105D7B	Flagellar biosynthesis protein flha
G6548_RS14840	ENOG4105D00	flagellar biosynthetic protein flhB
G6548_RS14865	ENOG4107KDV	flagellar M-ring protein FLIF
G6548_RS14875	ENOG4105DD5	Flagellar motor switch protein
G6548_RS14880	ENOG4105CN7	Flagellar biosynthetic protein FliP
G6548_RS14885	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
G6548_RS14920	ENOG4108YXV	Transcriptional regulator
G6548_RS14925	ENOG4105ER2	Ompa motb domain protein
G6548_RS14935	ENOG4107RD7	Flagellar Motor Protein, MotA
G6548_RS14945	ENOG4105BZU	Histidine kinase
G6548_RS14985	ENOG41061H0	Monooxygenase
G6548_RS15010	ENOG4105C2C	drug resistance transporter, Bcr CflA
G6548_RS15020	ENOG4105BZS	acriflavin resistance protein
G6548_RS15045	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
G6548_RS15055	ENOG4105D2B	acyl-CoA dehydrogenase
G6548_RS15060	ENOG4108KC2	acyl-Coa dehydrogenase
G6548_RS15065	ENOG4105CHR	reductase
G6548_RS15070	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
G6548_RS15075	ENOG4105CHU	acetyl-coa acetyltransferase
G6548_RS15080	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G6548_RS15100	ENOG4105C32	Amino acid ABC transporter (Permease)
G6548_RS15110	ENOG4105C0Z	ABC transporter
G6548_RS15115	ENOG4108IV0	ABC, transporter
G6548_RS15120	ENOG4107S1E	Beta-lactamase
G6548_RS15125	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G6548_RS15130	ENOG4105C29	acyl-CoA thioesterase
G6548_RS15145	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
G6548_RS15150	ENOG4107ZQV	short-chain dehydrogenase reductase
G6548_RS15165	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G6548_RS15180	ENOG4105DP0	ferredoxin-NADP reductase
G6548_RS15225	ENOG41083Z3	extracellular ligand-binding receptor
G6548_RS15230	ENOG4105C32	Amino acid ABC transporter (Permease)
G6548_RS15235	ENOG4105C0Z	ABC transporter
G6548_RS15240	ENOG4108IV0	ABC, transporter
G6548_RS15250	ENOG4105C2C	drug resistance transporter, Bcr CflA
G6548_RS15260	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
G6548_RS15270	ENOG4105F1J	Homogentisate 1,2-dioxygenase
G6548_RS15275	ENOG4107XU6	Glycosyl transferase (Group 1
G6548_RS15310	ENOG4105C58	cytochrome c oxidase accessory protein ccog
G6548_RS15315	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
G6548_RS15330	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
G6548_RS15335	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
G6548_RS15340	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
G6548_RS15345	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS15365	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
G6548_RS15375	ENOG41073TP	transcriptional regulator
G6548_RS15385	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS15395	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
G6548_RS15410	ENOG4105G9V	cytochrome C
G6548_RS15420	ENOG4105EMN	RNA polymerase sigma factor
G6548_RS15425	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G6548_RS15435	ENOG4105BZU	Histidine kinase
G6548_RS15450	ENOG4105F2C	Acetyl-CoA acetyltransferase
G6548_RS15485	ENOG4105CYM	Glutathione S-transferase
G6548_RS15495	ENOG4105C7K	acetolactate synthase
G6548_RS15505	ENOG4106A3M	Cytochrome p-450
G6548_RS15520	ENOG4105C26	Dehydrogenase
G6548_RS15525	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G6548_RS15530	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
G6548_RS15540	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS15565	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
G6548_RS15575	ENOG4105CGA	flagellar basal-body rod protein FlgG
G6548_RS15580	ENOG4105KTQ	flagellar basal-body rod protein
G6548_RS15605	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
G6548_RS15630	ENOG4108Q5F	Tetr family transcriptional regulator
G6548_RS15645	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS15665	ENOG4105C08	Histidine kinase
G6548_RS15670	ENOG4105DUM	transcriptional regulator, lysR family
G6548_RS15675	ENOG4105HMI	Membrane
G6548_RS15690	ENOG4105C09	Bile acid
G6548_RS15700	ENOG4108RCM	Nitroreductase
G6548_RS15705	ENOG4105BZS	acriflavin resistance protein
G6548_RS15710	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
G6548_RS15725	ENOG4108UKI	Enoyl-CoA hydratase
G6548_RS15750	ENOG4105EYM	Major Facilitator superfamily
G6548_RS15755	ENOG4105E0K	tonB-dependent siderophore receptor
G6548_RS15775	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G6548_RS15785	ENOG4105KT7	mgtC SapB transporter
G6548_RS15810	ENOG4106RE7	Cytochrome
G6548_RS15815	ENOG4107T5V	SNARE associated Golgi
G6548_RS15820	ENOG4105CUB	amino acid
G6548_RS15825	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
G6548_RS15830	ENOG4105BZ9	Cytochrome C oxidase, subunit I
G6548_RS15860	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS15865	ENOG4105CH5	extracellular solute-binding protein, family 7
G6548_RS15895	ENOG4108J59	Extracellular solute-binding protein, family 5
G6548_RS15915	ENOG4105CH2	amidohydrolase
G6548_RS15920	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
G6548_RS15965	ENOG4105C0B	DNA polymerase III (alpha subunit)
G6548_RS15970	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
G6548_RS15985	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS15990	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
G6548_RS15995	ENOG4105CIF	Ornithine Cyclodeaminase
G6548_RS16000	ENOG4106NZI	LysR family Transcriptional regulator
G6548_RS16005	ENOG4105M4H	endoribonuclease L-psp
G6548_RS16010	ENOG4105JSC	dimethylmenaquinone methyltransferase
G6548_RS16015	ENOG4105DEF	Extracellular solute-binding protein, family 5
G6548_RS16025	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G6548_RS16030	ENOG4105C3U	ABC transporter
G6548_RS16035	ENOG4108JQ7	(ABC) transporter
G6548_RS16065	ENOG4105CEY	Amp-dependent synthetase and ligase
G6548_RS16095	ENOG4105EA8	2-Nitropropane dioxygenase
G6548_RS16100	ENOG4105E39	Enoyl-CoA hydratase
G6548_RS16105	ENOG4105CC9	acyl-Coa dehydrogenase
G6548_RS16110	ENOG4105C1G	acyl-Coa dehydrogenase
G6548_RS16140	ENOG4108UKI	Enoyl-CoA hydratase
G6548_RS16145	ENOG4108UKI	Enoyl-CoA hydratase
G6548_RS16150	ENOG4105CHU	acetyl-coa acetyltransferase
G6548_RS16165	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS16170	ENOG4105CHU	acetyl-coa acetyltransferase
G6548_RS16175	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
G6548_RS16185	ENOG4106YT9	Enoyl-CoA hydratase
G6548_RS16195	ENOG410846T	CoA-transferase family III
G6548_RS16200	ENOG4105CHR	reductase
G6548_RS16220	ENOG4105CHR	reductase
G6548_RS16255	ENOG4108V0P	LemA family
G6548_RS16295	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
G6548_RS16305	ENOG4108JQ9	ABC transporter
G6548_RS16310	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
G6548_RS16350	ENOG410642W	LysR family Transcriptional regulator
G6548_RS16355	ENOG4105CC0	LysR family Transcriptional regulator
G6548_RS16380	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS16400	ENOG4107NQ8	LysR family Transcriptional regulator
G6548_RS16405	ENOG41067SE	Tetr family transcriptional regulator
G6548_RS16410	ENOG4105ENX	hydrolase
G6548_RS16430	ENOG4105E1F	short-chain dehydrogenase reductase
G6548_RS16440	ENOG4105ETT	transcriptional Regulator, LysR family
G6548_RS16445	ENOG4108JEH	abc transporter atp-binding protein
G6548_RS16450	ENOG4105E89	ABC transporter
G6548_RS16455	ENOG4105DSP	amino acid AbC transporter
G6548_RS16460	ENOG4106YG3	ABC transporter
G6548_RS16465	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
G6548_RS16480	ENOG4105CIF	Ornithine Cyclodeaminase
G6548_RS16495	ENOG4105EQR	Transposase IS116 IS110 IS902
G6548_RS16530	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
G6548_RS16535	ENOG4105EUB	pirin domain protein
G6548_RS16560	ENOG4105GVR	general secretion pathway protein D
G6548_RS16570	ENOG4105X5Z	General secretion pathway protein I
G6548_RS16580	ENOG4108VAU	general secretion pathway protein G
G6548_RS16595	ENOG4107QHF	type ii secretion system protein e
G6548_RS16600	ENOG4105D7Q	type ii secretion system
G6548_RS16615	ENOG4108WWZ	General secretion pathway protein J
G6548_RS16650	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS16660	ENOG4108NDG	TRAP dicarboxylate
G6548_RS16665	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G6548_RS16670	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G6548_RS16705	ENOG4107S3R	L-aspartate oxidase
G6548_RS16710	ENOG4105CHR	reductase
G6548_RS16720	ENOG4105CNV	Aldolase
G6548_RS16735	ENOG4105ETE	Transcriptional regulator (LacI family
G6548_RS16755	ENOG4105E39	Enoyl-CoA hydratase
G6548_RS16765	ENOG4107MVR	Transcriptional regulator
G6548_RS16805	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
G6548_RS16820	ENOG4105BZU	Histidine kinase
G6548_RS16825	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
G6548_RS16830	ENOG4105EHG	Permease protein
G6548_RS16835	ENOG4107R4I	Periplasmic binding protein
G6548_RS16840	ENOG4106QJH	hemin transport protein
G6548_RS16845	ENOG4105X58	receptor
G6548_RS16860	ENOG4105E3B	Multicopper oxidase
G6548_RS16890	ENOG4106NZI	LysR family Transcriptional regulator
G6548_RS16910	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
G6548_RS16915	ENOG4105DHU	Bile acid
G6548_RS16930	ENOG41086VY	Fic/DOC family
G6548_RS16940	ENOG4105BZU	Histidine kinase
G6548_RS16985	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
G6548_RS17025	ENOG4105CEY	Amp-dependent synthetase and ligase
G6548_RS17035	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
G6548_RS17050	ENOG4105EQR	Transposase IS116 IS110 IS902
G6548_RS17080	ENOG4107RIQ	Sulfate adenylate transferase
G6548_RS17085	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
G6548_RS17090	ENOG4107QQG	Dehydrogenase
G6548_RS17095	ENOG4107R5Z	Oxidoreductase domain protein
G6548_RS17100	ENOG4105J5G	Transferase hexapeptide repeat containing protein
G6548_RS17105	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G6548_RS17115	ENOG4107RA4	Glycosyl transferase (Group 1
G6548_RS17125	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
G6548_RS17135	ENOG4107STW	synthase
G6548_RS17145	ENOG4105CGN	Glycosyl transferase (Group 1
G6548_RS17150	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
G6548_RS17155	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
G6548_RS17165	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
G6548_RS17170	ENOG4105D3Q	Sugar transferase
G6548_RS17175	ENOG4107WZ3	Transferase
G6548_RS17180	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G6548_RS17240	ENOG4108RAV	Conserved protein
G6548_RS17250	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G6548_RS17255	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
G6548_RS17260	ENOG4105RD8	TRAP dicarboxylate transporter
G6548_RS17265	ENOG4105CEY	Amp-dependent synthetase and ligase
G6548_RS17270	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)