locus-tag	class	description
SULPSESMR1_RS00005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SULPSESMR1_RS00030	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS00035	COG0183	Belongs to the thiolase family
SULPSESMR1_RS00045	COG0427	acetyl-CoA hydrolase
SULPSESMR1_RS00060	COG1522	sequence-specific DNA binding
SULPSESMR1_RS00065	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS00085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULPSESMR1_RS00095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SULPSESMR1_RS00110	COG1215	transferase activity, transferring glycosyl groups
SULPSESMR1_RS00120	COG1737	Transcriptional regulator
SULPSESMR1_RS00145	COG0174	glutamine synthetase
SULPSESMR1_RS00160	COG2951	lytic endotransglycosylase activity
SULPSESMR1_RS00165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SULPSESMR1_RS00185	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS00190	COG0346	lactoylglutathione lyase activity
SULPSESMR1_RS00205	COG0778	Nitroreductase
SULPSESMR1_RS00215	COG2514	catechol 2,3-dioxygenase activity
SULPSESMR1_RS00220	COG0180	Tryptophanyl-tRNA synthetase
SULPSESMR1_RS00235	COG1473	amidohydrolase
SULPSESMR1_RS00245	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SULPSESMR1_RS00255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SULPSESMR1_RS00260	COG0792	nuclease activity
SULPSESMR1_RS00265	COG0189	ligase activity
SULPSESMR1_RS00275	COG0606	chelatase, subunit chli
SULPSESMR1_RS00290	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
SULPSESMR1_RS00305	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SULPSESMR1_RS00310	COG0756	dUTP diphosphatase activity
SULPSESMR1_RS00315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SULPSESMR1_RS00325	COG0484	heat shock protein binding
SULPSESMR1_RS00335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SULPSESMR1_RS00340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SULPSESMR1_RS00345	COG0772	Belongs to the SEDS family
SULPSESMR1_RS00350	COG0768	penicillin binding
SULPSESMR1_RS00380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SULPSESMR1_RS00390	COG3046	protein related to deoxyribodipyrimidine photolyase
SULPSESMR1_RS00410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SULPSESMR1_RS00420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SULPSESMR1_RS00425	COG0509	glycine decarboxylation via glycine cleavage system
SULPSESMR1_RS00430	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SULPSESMR1_RS00430	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SULPSESMR1_RS00440	COG1136	(ABC) transporter
SULPSESMR1_RS00450	COG1278	Cold shock
SULPSESMR1_RS00455	COG0493	'glutamate synthase
SULPSESMR1_RS00465	COG1309	transcriptional regulator
SULPSESMR1_RS00490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SULPSESMR1_RS00495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SULPSESMR1_RS00505	COG3916	Acyl-homoserine-lactone synthase
SULPSESMR1_RS00510	COG2197	response regulator
SULPSESMR1_RS00515	COG1376	ErfK ybiS ycfS ynhG family protein
SULPSESMR1_RS00520	COG0488	(ABC) transporter
SULPSESMR1_RS00530	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SULPSESMR1_RS00550	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
SULPSESMR1_RS00580	COG0556	nucleotide-excision repair
SULPSESMR1_RS00585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SULPSESMR1_RS00595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SULPSESMR1_RS00605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SULPSESMR1_RS00610	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SULPSESMR1_RS00615	COG1733	regulation of RNA biosynthetic process
SULPSESMR1_RS00620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SULPSESMR1_RS00625	COG2085	NADP oxidoreductase coenzyme F420-dependent
SULPSESMR1_RS00630	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS00635	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS00660	COG1268	BioY protein
SULPSESMR1_RS00685	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS00690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS00705	COG0601	transmembrane transport
SULPSESMR1_RS00710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS00725	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS00745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SULPSESMR1_RS00750	COG4608	Belongs to the ABC transporter superfamily
SULPSESMR1_RS00775	COG2205	protein histidine kinase activity
SULPSESMR1_RS00795	COG4774	siderophore transport
SULPSESMR1_RS00805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SULPSESMR1_RS00810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SULPSESMR1_RS00815	COG1120	ATPase activity
SULPSESMR1_RS00820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SULPSESMR1_RS00835	COG0626	cystathionine gamma-synthase activity
SULPSESMR1_RS00840	COG2819	hydrolase of the alpha beta superfamily
SULPSESMR1_RS00870	COG1280	lysine exporter protein (LysE YggA)
SULPSESMR1_RS00890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SULPSESMR1_RS00910	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS00915	COG2814	Major facilitator Superfamily
SULPSESMR1_RS00935	COG1072	(Pantothenic acid kinase))
SULPSESMR1_RS00970	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS01005	COG1609	Transcriptional regulator
SULPSESMR1_RS01010	COG2233	PERMEase
SULPSESMR1_RS01015	COG0402	S-adenosylhomocysteine deaminase activity
SULPSESMR1_RS01035	COG2032	superoxide dismutase activity
SULPSESMR1_RS01050	COG2205	protein histidine kinase activity
SULPSESMR1_RS01055	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
SULPSESMR1_RS01060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SULPSESMR1_RS01065	COG4191	Histidine kinase
SULPSESMR1_RS01065	COG0784	Response regulator, receiver
SULPSESMR1_RS01080	COG0729	surface antigen
SULPSESMR1_RS01100	COG0284	orotidine-5'-phosphate decarboxylase activity
SULPSESMR1_RS01105	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS01120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SULPSESMR1_RS01130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SULPSESMR1_RS01135	COG5328	Belongs to the UPF0262 family
SULPSESMR1_RS01165	COG0784	Response regulator, receiver
SULPSESMR1_RS01165	COG2205	protein histidine kinase activity
SULPSESMR1_RS01175	COG0481	GTPase activity
SULPSESMR1_RS01210	COG0438	transferase activity, transferring glycosyl groups
SULPSESMR1_RS01225	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SULPSESMR1_RS01230	COG0668	transmembrane transport
SULPSESMR1_RS01240	COG0513	Belongs to the DEAD box helicase family
SULPSESMR1_RS01245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS01250	COG0601	transmembrane transport
SULPSESMR1_RS01255	COG0747	negative chemotaxis
SULPSESMR1_RS01270	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS01270	COG1250	3-hydroxyacyl-CoA dehydrogenase
SULPSESMR1_RS01275	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS01280	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS01290	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS01295	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS01305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SULPSESMR1_RS01310	COG1070	Carbohydrate kinase
SULPSESMR1_RS01330	COG4213	ABC transporter substrate-binding protein
SULPSESMR1_RS01335	COG4214	carbohydrate transport
SULPSESMR1_RS01345	COG0837	glucose binding
SULPSESMR1_RS01350	COG3971	2-oxopent-4-enoate hydratase activity
SULPSESMR1_RS01355	COG0179	Fumarylacetoacetate (FAA) hydrolase
SULPSESMR1_RS01370	COG1012	belongs to the aldehyde dehydrogenase family
SULPSESMR1_RS01385	COG1012	belongs to the aldehyde dehydrogenase family
SULPSESMR1_RS01390	COG1414	Transcriptional regulator
SULPSESMR1_RS01395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SULPSESMR1_RS01415	COG0604	alcohol dehydrogenase
SULPSESMR1_RS01430	COG2814	Major facilitator Superfamily
SULPSESMR1_RS01440	COG1940	carbohydrate kinase activity
SULPSESMR1_RS01450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SULPSESMR1_RS01470	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS01475	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SULPSESMR1_RS01490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SULPSESMR1_RS01490	COG0300	oxidoreductase activity
SULPSESMR1_RS01490	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS01490	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS01490	COG3321	synthase
SULPSESMR1_RS01515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SULPSESMR1_RS01525	COG0277	FAD linked oxidase domain protein
SULPSESMR1_RS01545	COG0667	Aldo Keto reductase
SULPSESMR1_RS01560	COG3443	Belongs to the bacterial solute-binding protein 9 family
SULPSESMR1_RS01570	COG1079	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS01575	COG4603	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS01580	COG3845	ABC transporter
SULPSESMR1_RS01590	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SULPSESMR1_RS01615	COG0124	histidyl-tRNA synthetase
SULPSESMR1_RS01620	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SULPSESMR1_RS01625	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SULPSESMR1_RS01675	COG2963	transposase activity
SULPSESMR1_RS01690	COG0747	negative chemotaxis
SULPSESMR1_RS01695	COG0601	transmembrane transport
SULPSESMR1_RS01700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS01710	COG1473	amidohydrolase
SULPSESMR1_RS01715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULPSESMR1_RS01745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SULPSESMR1_RS01840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SULPSESMR1_RS01845	COG0165	Argininosuccinate lyase
SULPSESMR1_RS01860	COG0019	diaminopimelate decarboxylase activity
SULPSESMR1_RS01880	COG2884	Cell division ATP-binding protein ftsE
SULPSESMR1_RS01915	COG0508	dehydrogenase complex catalyzes the overall conversion of
SULPSESMR1_RS01920	COG0567	Dehydrogenase, E1 component
SULPSESMR1_RS01940	COG0045	succinate-CoA ligase (ADP-forming) activity
SULPSESMR1_RS01950	COG0039	L-malate dehydrogenase activity
SULPSESMR1_RS01980	COG2030	dehydratase
SULPSESMR1_RS02020	COG0813	purine-nucleoside phosphorylase activity
SULPSESMR1_RS02030	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULPSESMR1_RS02030	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULPSESMR1_RS02035	COG2937	Belongs to the GPAT DAPAT family
SULPSESMR1_RS02040	COG0604	alcohol dehydrogenase
SULPSESMR1_RS02060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SULPSESMR1_RS02070	COG0730	response to heat
SULPSESMR1_RS02075	COG1079	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS02080	COG4603	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS02085	COG3845	ABC transporter
SULPSESMR1_RS02090	COG1744	ABC transporter substrate-binding protein PnrA-like
SULPSESMR1_RS02105	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SULPSESMR1_RS02140	COG1272	protein, Hemolysin III
SULPSESMR1_RS02155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SULPSESMR1_RS02165	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SULPSESMR1_RS02170	COG3524	carbohydrate:proton symporter activity
SULPSESMR1_RS02180	COG1230	cation diffusion facilitator family transporter
SULPSESMR1_RS02190	COG1573	uracil-dna glycosylase
SULPSESMR1_RS02215	COG2943	transferase activity, transferring hexosyl groups
SULPSESMR1_RS02220	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
SULPSESMR1_RS02235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SULPSESMR1_RS02260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SULPSESMR1_RS02275	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SULPSESMR1_RS02280	COG1643	Atp-dependent helicase
SULPSESMR1_RS02285	COG1703	isobutyryl-CoA mutase activity
SULPSESMR1_RS02290	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SULPSESMR1_RS02310	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS02315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SULPSESMR1_RS02320	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SULPSESMR1_RS02325	COG0424	maF-like protein
SULPSESMR1_RS02335	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
SULPSESMR1_RS02385	COG0463	Glycosyl transferase, family 2
SULPSESMR1_RS02390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SULPSESMR1_RS02415	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SULPSESMR1_RS02425	COG3387	PFAM Glycoside hydrolase 15-related
SULPSESMR1_RS02435	COG2323	membrane
SULPSESMR1_RS02445	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SULPSESMR1_RS02450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SULPSESMR1_RS02455	COG3842	ATPase activity
SULPSESMR1_RS02470	COG2186	Transcriptional regulator
SULPSESMR1_RS02480	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS02480	COG1250	3-hydroxyacyl-CoA dehydrogenase
SULPSESMR1_RS02505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SULPSESMR1_RS02510	COG4608	Belongs to the ABC transporter superfamily
SULPSESMR1_RS02515	COG0444	Belongs to the ABC transporter superfamily
SULPSESMR1_RS02520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS02525	COG0601	transmembrane transport
SULPSESMR1_RS02530	COG0747	negative chemotaxis
SULPSESMR1_RS02540	COG0402	S-adenosylhomocysteine deaminase activity
SULPSESMR1_RS02545	COG1295	ribonuclease BN
SULPSESMR1_RS02550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SULPSESMR1_RS02555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SULPSESMR1_RS02560	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SULPSESMR1_RS02590	COG5002	protein histidine kinase activity
SULPSESMR1_RS02605	COG2194	sulfuric ester hydrolase activity
SULPSESMR1_RS02615	COG0688	phosphatidylethanolamine metabolic process
SULPSESMR1_RS02635	COG3454	Phosphonate metabolism
SULPSESMR1_RS02645	COG4778	phosphonate C-P lyase system protein PhnL
SULPSESMR1_RS02650	COG4107	phosphonate C-P lyase system protein PhnK
SULPSESMR1_RS02655	COG3627	carbon phosphorus lyase activity
SULPSESMR1_RS02660	COG3626	phosphonate metabolism
SULPSESMR1_RS02665	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
SULPSESMR1_RS02670	COG3624	Phosphonate C-P lyase system protein PhnG
SULPSESMR1_RS02675	COG2188	Transcriptional regulator
SULPSESMR1_RS02680	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS02695	COG3959	Transketolase, thiamine diphosphate binding domain
SULPSESMR1_RS02700	COG3958	Transketolase
SULPSESMR1_RS02705	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS02715	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS02720	COG1802	Transcriptional regulator
SULPSESMR1_RS02725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SULPSESMR1_RS02735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS02745	COG0697	spore germination
SULPSESMR1_RS02750	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS02755	COG0179	Fumarylacetoacetate (FAA) hydrolase
SULPSESMR1_RS02765	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS02785	COG1414	Transcriptional regulator
SULPSESMR1_RS02805	COG5441	Belongs to the UPF0261 family
SULPSESMR1_RS02815	COG0129	dihydroxy-acid dehydratase activity
SULPSESMR1_RS02830	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SULPSESMR1_RS02870	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SULPSESMR1_RS02875	COG0830	nickel cation binding
SULPSESMR1_RS02880	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SULPSESMR1_RS02885	COG0804	urea catabolic process
SULPSESMR1_RS02895	COG0832	Belongs to the urease beta subunit family
SULPSESMR1_RS02905	COG0831	urea catabolic process
SULPSESMR1_RS02910	COG0829	nickel cation binding
SULPSESMR1_RS02920	COG0559	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS02925	COG1172	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS02950	COG1132	(ABC) transporter
SULPSESMR1_RS02955	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS02960	COG0657	acetylesterase activity
SULPSESMR1_RS02965	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SULPSESMR1_RS02975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS02980	COG0601	transmembrane transport
SULPSESMR1_RS02995	COG2379	hydroxypyruvate reductase
SULPSESMR1_RS03000	COG1490	D-aminoacyl-tRNA deacylase activity
SULPSESMR1_RS03030	COG3853	Toxic anion resistance protein (TelA)
SULPSESMR1_RS03045	COG1187	pseudouridine synthase activity
SULPSESMR1_RS03050	COG0590	tRNA wobble adenosine to inosine editing
SULPSESMR1_RS03055	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SULPSESMR1_RS03060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SULPSESMR1_RS03065	COG0154	amidase activity
SULPSESMR1_RS03085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULPSESMR1_RS03090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SULPSESMR1_RS03100	COG3813	Protein conserved in bacteria
SULPSESMR1_RS03105	COG0670	Belongs to the BI1 family
SULPSESMR1_RS03115	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS03120	COG1396	sequence-specific DNA binding
SULPSESMR1_RS03125	COG0483	inositol monophosphate 1-phosphatase activity
SULPSESMR1_RS03135	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SULPSESMR1_RS03140	COG0402	S-adenosylhomocysteine deaminase activity
SULPSESMR1_RS03145	COG2239	Acts as a magnesium transporter
SULPSESMR1_RS03150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SULPSESMR1_RS03155	COG1692	metallophosphoesterase
SULPSESMR1_RS03160	COG0471	metal ion transport
SULPSESMR1_RS03160	COG3273	potassium ion transport
SULPSESMR1_RS03165	COG0628	permease
SULPSESMR1_RS03175	COG0471	metal ion transport
SULPSESMR1_RS03175	COG3273	potassium ion transport
SULPSESMR1_RS03180	COG0217	transcriptional regulatory protein
SULPSESMR1_RS03205	COG1309	transcriptional regulator
SULPSESMR1_RS03210	COG3119	arylsulfatase activity
SULPSESMR1_RS03235	COG3800	Transcriptional regulator
SULPSESMR1_RS03235	COG1396	sequence-specific DNA binding
SULPSESMR1_RS03245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SULPSESMR1_RS03270	COG4770	biotin carboxylase activity
SULPSESMR1_RS03285	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULPSESMR1_RS03285	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULPSESMR1_RS03300	COG0484	heat shock protein binding
SULPSESMR1_RS03315	COG0248	Ppx GppA phosphatase
SULPSESMR1_RS03330	COG0628	permease
SULPSESMR1_RS03340	COG2195	Cleaves the N-terminal amino acid of tripeptides
SULPSESMR1_RS03345	COG0442	prolyl-tRNA aminoacylation
SULPSESMR1_RS03360	COG1136	(ABC) transporter
SULPSESMR1_RS03380	COG2824	Alkylphosphonate utilization operon protein PhnA
SULPSESMR1_RS03390	COG0187	DNA topoisomerase II activity
SULPSESMR1_RS03405	COG3128	pkhd-type hydroxylase
SULPSESMR1_RS03415	COG2267	carboxylic ester hydrolase activity
SULPSESMR1_RS03430	COG0534	Mate efflux family protein
SULPSESMR1_RS03440	COG2826	transposase and inactivated derivatives, IS30 family
SULPSESMR1_RS03445	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS03450	COG2826	transposase and inactivated derivatives, IS30 family
SULPSESMR1_RS03485	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS03520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SULPSESMR1_RS03540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SULPSESMR1_RS03555	COG1136	(ABC) transporter
SULPSESMR1_RS03640	COG0398	Pfam SNARE associated Golgi protein
SULPSESMR1_RS03670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULPSESMR1_RS03680	COG3842	ATPase activity
SULPSESMR1_RS03685	COG1176	ABC-type spermidine putrescine transport system, permease component I
SULPSESMR1_RS03690	COG4149	molybdate abc transporter
SULPSESMR1_RS03695	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SULPSESMR1_RS03700	COG4948	Mandelate Racemase Muconate Lactonizing
SULPSESMR1_RS03730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SULPSESMR1_RS03735	COG0667	Aldo Keto reductase
SULPSESMR1_RS03745	COG1172	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS03750	COG1129	ABC transporter
SULPSESMR1_RS03765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SULPSESMR1_RS03790	COG1609	Transcriptional regulator
SULPSESMR1_RS03820	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
SULPSESMR1_RS03855	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SULPSESMR1_RS03865	COG1278	Cold shock
SULPSESMR1_RS03870	COG1393	Belongs to the ArsC family
SULPSESMR1_RS03885	COG3220	belongs to the UPF0276 family
SULPSESMR1_RS03895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SULPSESMR1_RS03900	COG2814	Major facilitator Superfamily
SULPSESMR1_RS03930	COG4166	transmembrane transport
SULPSESMR1_RS03940	COG3243	poly(R)-hydroxyalkanoic acid synthase
SULPSESMR1_RS03955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SULPSESMR1_RS03960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULPSESMR1_RS03965	COG0174	glutamine synthetase
SULPSESMR1_RS03970	COG0519	Catalyzes the synthesis of GMP from XMP
SULPSESMR1_RS03975	COG0174	glutamine synthetase
SULPSESMR1_RS03980	COG4160	amino acid transport
SULPSESMR1_RS03985	COG4215	(ABC) transporter
SULPSESMR1_RS04025	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
SULPSESMR1_RS04030	COG0504	CTP synthase activity
SULPSESMR1_RS04060	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SULPSESMR1_RS04090	COG1760	l-serine dehydratase
SULPSESMR1_RS04100	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SULPSESMR1_RS04110	COG0330	HflC and HflK could
SULPSESMR1_RS04115	COG0330	HflC and HflK could
SULPSESMR1_RS04125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SULPSESMR1_RS04145	COG0151	Belongs to the GarS family
SULPSESMR1_RS04150	COG1570	exodeoxyribonuclease VII activity
SULPSESMR1_RS04160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SULPSESMR1_RS04170	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SULPSESMR1_RS04175	COG0552	protein localization to endoplasmic reticulum
SULPSESMR1_RS04185	COG2917	probably involved in intracellular septation
SULPSESMR1_RS04200	COG1469	GTP cyclohydrolase I activity
SULPSESMR1_RS04210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SULPSESMR1_RS04230	COG0752	glycyl-tRNA synthetase alpha subunit
SULPSESMR1_RS04240	COG0751	glycine-tRNA ligase activity
SULPSESMR1_RS04245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SULPSESMR1_RS04245	COG0574	Belongs to the PEP-utilizing enzyme family
SULPSESMR1_RS04255	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SULPSESMR1_RS04260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SULPSESMR1_RS04265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SULPSESMR1_RS04280	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SULPSESMR1_RS04295	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SULPSESMR1_RS04310	COG1802	Transcriptional regulator
SULPSESMR1_RS04320	COG0505	Belongs to the CarA family
SULPSESMR1_RS04325	COG1610	YqeY-like protein
SULPSESMR1_RS04345	COG0321	lipoyl(octanoyl) transferase activity
SULPSESMR1_RS04360	COG1295	ribonuclease BN
SULPSESMR1_RS04370	COG1234	tRNA 3'-trailer cleavage
SULPSESMR1_RS04375	COG0084	hydrolase, TatD family'
SULPSESMR1_RS04385	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SULPSESMR1_RS04390	COG1686	Belongs to the peptidase S11 family
SULPSESMR1_RS04410	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS04415	COG1250	3-hydroxyacyl-CoA dehydrogenase
SULPSESMR1_RS04425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SULPSESMR1_RS04435	COG1574	metal-dependent hydrolase with the TIM-barrel fold
SULPSESMR1_RS04440	COG1309	transcriptional regulator
SULPSESMR1_RS04445	COG3842	ATPase activity
SULPSESMR1_RS04450	COG1176	ABC-type spermidine putrescine transport system, permease component I
SULPSESMR1_RS04455	COG1177	transmembrane transport
SULPSESMR1_RS04465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SULPSESMR1_RS04475	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SULPSESMR1_RS04475	COG3008	intermembrane lipid transfer
SULPSESMR1_RS04480	COG2995	paraquat-inducible protein a
SULPSESMR1_RS04495	COG1294	oxidase, subunit
SULPSESMR1_RS04500	COG1271	oxidase subunit
SULPSESMR1_RS04510	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SULPSESMR1_RS04515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SULPSESMR1_RS04520	COG4558	Periplasmic binding protein
SULPSESMR1_RS04525	COG3720	iron ion transport
SULPSESMR1_RS04530	COG1629	transport
SULPSESMR1_RS04540	COG0811	peptide transport
SULPSESMR1_RS04590	COG1175	transmembrane transport
SULPSESMR1_RS04605	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS04610	COG1454	alcohol dehydrogenase
SULPSESMR1_RS04620	COG1162	GTPase activity
SULPSESMR1_RS04630	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS04635	COG1846	Transcriptional regulator
SULPSESMR1_RS04640	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS04640	COG1250	3-hydroxyacyl-CoA dehydrogenase
SULPSESMR1_RS04655	COG3483	tryptophan 2,3-dioxygenase activity
SULPSESMR1_RS04670	COG0559	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS04695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SULPSESMR1_RS04700	COG1121	(ABC) transporter
SULPSESMR1_RS04720	COG0740	serine-type endopeptidase activity
SULPSESMR1_RS04725	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SULPSESMR1_RS04750	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
SULPSESMR1_RS04755	COG0439	Biotin carboxylase
SULPSESMR1_RS04760	COG0511	ligase activity, forming carbon-carbon bonds
SULPSESMR1_RS04775	COG0410	ABC transporter
SULPSESMR1_RS04790	COG0559	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS04800	COG3800	Transcriptional regulator
SULPSESMR1_RS04800	COG1396	sequence-specific DNA binding
SULPSESMR1_RS04805	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS04830	COG2391	methyltransferase activity
SULPSESMR1_RS04860	COG0811	peptide transport
SULPSESMR1_RS04875	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SULPSESMR1_RS04880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SULPSESMR1_RS04890	COG4206	TonB-dependent receptor
SULPSESMR1_RS04895	COG3750	Belongs to the UPF0335 family
SULPSESMR1_RS04900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SULPSESMR1_RS04900	COG1648	precorrin-2 dehydrogenase activity
SULPSESMR1_RS04905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SULPSESMR1_RS04910	COG0243	molybdopterin cofactor binding
SULPSESMR1_RS04920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SULPSESMR1_RS04925	COG1116	anion transmembrane transporter activity
SULPSESMR1_RS04925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SULPSESMR1_RS04930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SULPSESMR1_RS04935	COG1116	anion transmembrane transporter activity
SULPSESMR1_RS04935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SULPSESMR1_RS04940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SULPSESMR1_RS04945	COG3707	response regulator
SULPSESMR1_RS04960	COG0800	Aldolase
SULPSESMR1_RS04965	COG0129	dihydroxy-acid dehydratase activity
SULPSESMR1_RS04970	COG1840	ABC-type Fe3 transport system, periplasmic component
SULPSESMR1_RS04975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SULPSESMR1_RS04985	COG0563	adenylate kinase activity
SULPSESMR1_RS04990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULPSESMR1_RS05010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SULPSESMR1_RS05015	COG2814	Major facilitator Superfamily
SULPSESMR1_RS05020	COG0730	response to heat
SULPSESMR1_RS05025	COG2205	protein histidine kinase activity
SULPSESMR1_RS05035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SULPSESMR1_RS05040	COG4235	cytochrome complex assembly
SULPSESMR1_RS05045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULPSESMR1_RS05060	COG0446	pyridine nucleotide-disulphide oxidoreductase
SULPSESMR1_RS05060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SULPSESMR1_RS05090	COG5265	(ABC) transporter
SULPSESMR1_RS05120	COG1160	GTP binding
SULPSESMR1_RS05135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SULPSESMR1_RS05140	COG1862	Preprotein translocase
SULPSESMR1_RS05145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SULPSESMR1_RS05150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SULPSESMR1_RS05160	COG3737	Protein of unknown function (DUF498/DUF598)
SULPSESMR1_RS05165	COG4133	protoheme IX ABC transporter activity
SULPSESMR1_RS05170	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SULPSESMR1_RS05175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SULPSESMR1_RS05185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SULPSESMR1_RS05190	COG2031	fatty acid transporter
SULPSESMR1_RS05195	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS05235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SULPSESMR1_RS05235	COG3453	Protein conserved in bacteria
SULPSESMR1_RS05240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SULPSESMR1_RS05250	COG1268	BioY protein
SULPSESMR1_RS05285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SULPSESMR1_RS05285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SULPSESMR1_RS05295	COG0544	peptidyl-prolyl cis-trans isomerase activity
SULPSESMR1_RS05320	COG0544	peptidyl-prolyl cis-trans isomerase activity
SULPSESMR1_RS05325	COG1196	nuclear chromosome segregation
SULPSESMR1_RS05325	COG0741	lytic transglycosylase activity
SULPSESMR1_RS05325	COG0739	heme binding
SULPSESMR1_RS05330	COG0737	Belongs to the 5'-nucleotidase family
SULPSESMR1_RS05335	COG0359	binds to the 23S rRNA
SULPSESMR1_RS05340	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SULPSESMR1_RS05345	COG0360	Binds together with S18 to 16S ribosomal RNA
SULPSESMR1_RS05355	COG2353	YceI-like domain
SULPSESMR1_RS05360	COG3038	cytochrome b561
SULPSESMR1_RS05365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SULPSESMR1_RS05375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SULPSESMR1_RS05385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SULPSESMR1_RS05390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SULPSESMR1_RS05460	COG0508	dehydrogenase complex catalyzes the overall conversion of
SULPSESMR1_RS05465	COG0508	dehydrogenase complex catalyzes the overall conversion of
SULPSESMR1_RS05465	COG0022	dehydrogenase e1 component
SULPSESMR1_RS05470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SULPSESMR1_RS05475	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
SULPSESMR1_RS05480	COG0126	phosphoglycerate kinase activity
SULPSESMR1_RS05505	COG0739	heme binding
SULPSESMR1_RS05510	COG2833	Protein of unknown function (DUF455)
SULPSESMR1_RS05515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SULPSESMR1_RS05525	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SULPSESMR1_RS05530	COG2814	Major facilitator Superfamily
SULPSESMR1_RS05540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULPSESMR1_RS05545	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS05560	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SULPSESMR1_RS05585	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS05605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SULPSESMR1_RS05630	COG2354	Protein conserved in bacteria
SULPSESMR1_RS05635	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SULPSESMR1_RS05655	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SULPSESMR1_RS05670	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SULPSESMR1_RS05695	COG2885	chlorophyll binding
SULPSESMR1_RS05700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SULPSESMR1_RS05720	COG0175	sulfate reduction
SULPSESMR1_RS05725	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SULPSESMR1_RS05735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SULPSESMR1_RS05735	COG1648	precorrin-2 dehydrogenase activity
SULPSESMR1_RS05740	COG1522	sequence-specific DNA binding
SULPSESMR1_RS05745	COG2124	cytochrome p450
SULPSESMR1_RS05760	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SULPSESMR1_RS05765	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
SULPSESMR1_RS05770	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS05780	COG1280	lysine exporter protein (LysE YggA)
SULPSESMR1_RS05785	COG0149	triose-phosphate isomerase activity
SULPSESMR1_RS05800	COG0316	Belongs to the HesB IscA family
SULPSESMR1_RS05825	COG2151	metal-sulfur cluster biosynthetic enzyme
SULPSESMR1_RS05830	COG0189	ligase activity
SULPSESMR1_RS05830	COG4067	protein conserved in archaea
SULPSESMR1_RS05850	COG0343	queuine tRNA-ribosyltransferase activity
SULPSESMR1_RS05855	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SULPSESMR1_RS05870	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SULPSESMR1_RS05880	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SULPSESMR1_RS05940	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS05965	COG2188	Transcriptional regulator
SULPSESMR1_RS05970	COG3618	amidohydrolase
SULPSESMR1_RS05985	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS05990	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULPSESMR1_RS05990	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULPSESMR1_RS06000	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULPSESMR1_RS06000	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULPSESMR1_RS06005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SULPSESMR1_RS06010	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS06050	COG1741	Belongs to the pirin family
SULPSESMR1_RS06075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULPSESMR1_RS06085	COG0156	8-amino-7-oxononanoate synthase activity
SULPSESMR1_RS06095	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SULPSESMR1_RS06110	COG0436	Aminotransferase
SULPSESMR1_RS06115	COG0860	N-Acetylmuramoyl-L-alanine amidase
SULPSESMR1_RS06120	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SULPSESMR1_RS06125	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SULPSESMR1_RS06160	COG0028	Belongs to the TPP enzyme family
SULPSESMR1_RS06175	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SULPSESMR1_RS06190	COG2070	2-Nitropropane dioxygenase
SULPSESMR1_RS06195	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
SULPSESMR1_RS06275	COG0542	response to heat
SULPSESMR1_RS06285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SULPSESMR1_RS06295	COG0316	Belongs to the HesB IscA family
SULPSESMR1_RS06300	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SULPSESMR1_RS06305	COG0018	arginyl-trna synthetase
SULPSESMR1_RS06315	COG1472	Belongs to the glycosyl hydrolase 3 family
SULPSESMR1_RS06320	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SULPSESMR1_RS06325	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SULPSESMR1_RS06335	COG0717	Belongs to the dCTP deaminase family
SULPSESMR1_RS06350	COG0776	regulation of translation
SULPSESMR1_RS06355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SULPSESMR1_RS06360	COG0416	fatty acid biosynthetic process
SULPSESMR1_RS06365	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SULPSESMR1_RS06385	COG0488	(ABC) transporter
SULPSESMR1_RS06400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SULPSESMR1_RS06405	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SULPSESMR1_RS06420	COG2198	Histidine kinase
SULPSESMR1_RS06420	COG5002	protein histidine kinase activity
SULPSESMR1_RS06420	COG0784	Response regulator, receiver
SULPSESMR1_RS06430	COG0148	phosphopyruvate hydratase activity
SULPSESMR1_RS06435	COG0697	spore germination
SULPSESMR1_RS06450	COG0513	Belongs to the DEAD box helicase family
SULPSESMR1_RS06455	COG0697	spore germination
SULPSESMR1_RS06460	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
SULPSESMR1_RS06480	COG3956	TIGRFAM MazG family protein
SULPSESMR1_RS06485	COG1473	amidohydrolase
SULPSESMR1_RS06505	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SULPSESMR1_RS06510	COG2890	protein-(glutamine-N5) methyltransferase activity
SULPSESMR1_RS06525	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SULPSESMR1_RS06530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SULPSESMR1_RS06540	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
SULPSESMR1_RS06555	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SULPSESMR1_RS06565	COG3577	Aspartyl protease
SULPSESMR1_RS06570	COG2095	MarC family integral membrane protein
SULPSESMR1_RS06575	COG0488	(ABC) transporter
SULPSESMR1_RS06580	COG0105	UTP biosynthetic process
SULPSESMR1_RS06620	COG0348	domain, Protein
SULPSESMR1_RS06625	COG2010	Cytochrome c
SULPSESMR1_RS06650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SULPSESMR1_RS06655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SULPSESMR1_RS06665	COG1177	transmembrane transport
SULPSESMR1_RS06670	COG1176	ABC-type spermidine putrescine transport system, permease component I
SULPSESMR1_RS06675	COG3842	ATPase activity
SULPSESMR1_RS06680	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SULPSESMR1_RS06685	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS06700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULPSESMR1_RS06705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SULPSESMR1_RS06710	COG0277	FAD linked oxidase domain protein
SULPSESMR1_RS06720	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS06730	COG2267	carboxylic ester hydrolase activity
SULPSESMR1_RS06735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SULPSESMR1_RS06745	COG4221	oxidoreductase activity
SULPSESMR1_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS06755	COG2084	Dehydrogenase
SULPSESMR1_RS06760	COG3395	kinase activity
SULPSESMR1_RS06765	COG0235	Class ii aldolase
SULPSESMR1_RS06770	COG2721	sulfolactate sulfo-lyase activity
SULPSESMR1_RS06775	COG3622	Belongs to the hyi family
SULPSESMR1_RS06790	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS06795	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS06805	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SULPSESMR1_RS06810	COG3639	organic phosphonate transmembrane transporter activity
SULPSESMR1_RS06820	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SULPSESMR1_RS06830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SULPSESMR1_RS06845	COG1238	metal cluster binding
SULPSESMR1_RS06850	COG0287	Prephenate dehydrogenase
SULPSESMR1_RS06855	COG2186	Transcriptional regulator
SULPSESMR1_RS06865	COG1850	ribulose-bisphosphate carboxylase activity
SULPSESMR1_RS06870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SULPSESMR1_RS06880	COG2072	flavoprotein involved in K transport
SULPSESMR1_RS06885	COG0385	Bile acid
SULPSESMR1_RS06890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SULPSESMR1_RS06895	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS06900	COG4372	Transposase
SULPSESMR1_RS06910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SULPSESMR1_RS06930	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SULPSESMR1_RS06935	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SULPSESMR1_RS06940	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SULPSESMR1_RS06950	COG2166	iron-sulfur cluster assembly
SULPSESMR1_RS06965	COG0393	Putative heavy-metal-binding
SULPSESMR1_RS06975	COG5012	cobalamin binding
SULPSESMR1_RS06985	COG1410	methionine synthase
SULPSESMR1_RS06985	COG0646	methionine synthase
SULPSESMR1_RS06995	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SULPSESMR1_RS07000	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SULPSESMR1_RS07005	COG0047	phosphoribosylformylglycinamidine synthase activity
SULPSESMR1_RS07015	COG2204	response regulator
SULPSESMR1_RS07020	COG1530	ribonuclease E activity
SULPSESMR1_RS07030	COG0659	secondary active sulfate transmembrane transporter activity
SULPSESMR1_RS07040	COG0425	Belongs to the sulfur carrier protein TusA family
SULPSESMR1_RS07045	COG0785	Cytochrome C biogenesis protein
SULPSESMR1_RS07055	COG2124	cytochrome p450
SULPSESMR1_RS07060	COG3588	fructose-bisphosphate aldolase
SULPSESMR1_RS07075	COG0114	fumarate hydratase activity
SULPSESMR1_RS07115	COG0604	alcohol dehydrogenase
SULPSESMR1_RS07125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SULPSESMR1_RS07130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SULPSESMR1_RS07135	COG0415	Belongs to the DNA photolyase family
SULPSESMR1_RS07140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SULPSESMR1_RS07150	COG0494	nUDIX hydrolase
SULPSESMR1_RS07160	COG3264	Mechanosensitive ion channel
SULPSESMR1_RS07160	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SULPSESMR1_RS07165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SULPSESMR1_RS07175	COG1228	amidohydrolase
SULPSESMR1_RS07185	COG1177	transmembrane transport
SULPSESMR1_RS07195	COG3842	ATPase activity
SULPSESMR1_RS07215	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SULPSESMR1_RS07230	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS07235	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SULPSESMR1_RS07240	COG0835	chemotaxis
SULPSESMR1_RS07250	COG0643	Histidine kinase
SULPSESMR1_RS07250	COG2198	Histidine kinase
SULPSESMR1_RS07250	COG0784	Response regulator, receiver
SULPSESMR1_RS07265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SULPSESMR1_RS07275	COG0248	Ppx GppA phosphatase
SULPSESMR1_RS07280	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
SULPSESMR1_RS07300	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS07315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS07320	COG0747	negative chemotaxis
SULPSESMR1_RS07330	COG4172	Belongs to the ABC transporter superfamily
SULPSESMR1_RS07335	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SULPSESMR1_RS07370	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SULPSESMR1_RS07370	COG3743	rRNA binding
SULPSESMR1_RS07375	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SULPSESMR1_RS07385	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SULPSESMR1_RS07390	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SULPSESMR1_RS07395	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SULPSESMR1_RS07420	COG0052	Belongs to the universal ribosomal protein uS2 family
SULPSESMR1_RS07425	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SULPSESMR1_RS07430	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SULPSESMR1_RS07435	COG2771	luxR family
SULPSESMR1_RS07440	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SULPSESMR1_RS07450	COG2130	NADP-dependent
SULPSESMR1_RS07465	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS07470	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS07480	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS07485	COG0183	Belongs to the thiolase family
SULPSESMR1_RS07545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULPSESMR1_RS07550	COG1946	Acyl-CoA thioesterase
SULPSESMR1_RS07560	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS07565	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS07580	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS07585	COG0033	Phosphoglucomutase
SULPSESMR1_RS07590	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS07600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SULPSESMR1_RS07605	COG5002	protein histidine kinase activity
SULPSESMR1_RS07610	COG0626	cystathionine gamma-synthase activity
SULPSESMR1_RS07620	COG0194	GDP metabolic process
SULPSESMR1_RS07625	COG1561	YicC-like family, N-terminal region
SULPSESMR1_RS07635	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SULPSESMR1_RS07645	COG2133	pyrroloquinoline quinone binding
SULPSESMR1_RS07680	COG0433	COG0433 Predicted ATPase
SULPSESMR1_RS07700	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SULPSESMR1_RS07705	COG2989	Protein conserved in bacteria
SULPSESMR1_RS07720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SULPSESMR1_RS07735	COG0719	Fe-S assembly protein
SULPSESMR1_RS07740	COG0396	ATPase activity
SULPSESMR1_RS07750	COG0719	Fe-S assembly protein
SULPSESMR1_RS07760	COG1959	2 iron, 2 sulfur cluster binding
SULPSESMR1_RS07765	COG2945	thiolester hydrolase activity
SULPSESMR1_RS07785	COG0538	isocitrate dehydrogenase activity
SULPSESMR1_RS07790	COG0121	glutamine amidotransferase
SULPSESMR1_RS07800	COG1522	sequence-specific DNA binding
SULPSESMR1_RS07805	COG2076	Multidrug Resistance protein
SULPSESMR1_RS07810	COG1217	gtp-binding protein TYPA
SULPSESMR1_RS07820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SULPSESMR1_RS07825	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SULPSESMR1_RS07845	COG0517	IMP dehydrogenase activity
SULPSESMR1_RS07845	COG0516	GMP reductase activity
SULPSESMR1_RS07860	COG2226	methyltransferase
SULPSESMR1_RS07880	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS07890	COG0166	Belongs to the GPI family
SULPSESMR1_RS07895	COG0363	glucosamine-6-phosphate deaminase activity
SULPSESMR1_RS07900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SULPSESMR1_RS07910	COG5425	PFAM Usg family protein
SULPSESMR1_RS07915	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SULPSESMR1_RS07925	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SULPSESMR1_RS07930	COG1612	heme a metabolic process
SULPSESMR1_RS07940	COG0352	thiamine-phosphate diphosphorylase activity
SULPSESMR1_RS07960	COG2313	pseudouridylate synthase activity
SULPSESMR1_RS07975	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS07980	COG4166	transmembrane transport
SULPSESMR1_RS08000	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SULPSESMR1_RS08005	COG2814	Major facilitator Superfamily
SULPSESMR1_RS08010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SULPSESMR1_RS08035	COG2084	Dehydrogenase
SULPSESMR1_RS08050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SULPSESMR1_RS08055	COG1923	regulation of RNA biosynthetic process
SULPSESMR1_RS08060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SULPSESMR1_RS08065	COG0569	domain protein
SULPSESMR1_RS08075	COG2204	response regulator
SULPSESMR1_RS08080	COG5000	phosphorelay sensor kinase activity
SULPSESMR1_RS08085	COG2204	response regulator
SULPSESMR1_RS08090	COG3852	Histidine kinase
SULPSESMR1_RS08095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SULPSESMR1_RS08100	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SULPSESMR1_RS08100	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SULPSESMR1_RS08105	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SULPSESMR1_RS08105	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SULPSESMR1_RS08120	COG0004	ammonium transporteR
SULPSESMR1_RS08130	COG2867	negative regulation of translational initiation
SULPSESMR1_RS08135	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SULPSESMR1_RS08145	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SULPSESMR1_RS08150	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SULPSESMR1_RS08165	COG5598	trimethylamine methyltransferase
SULPSESMR1_RS08170	COG0519	Catalyzes the synthesis of GMP from XMP
SULPSESMR1_RS08170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SULPSESMR1_RS08175	COG0697	spore germination
SULPSESMR1_RS08195	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SULPSESMR1_RS08205	COG2326	polyphosphate kinase activity
SULPSESMR1_RS08210	COG1309	transcriptional regulator
SULPSESMR1_RS08225	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SULPSESMR1_RS08230	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SULPSESMR1_RS08255	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SULPSESMR1_RS08265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SULPSESMR1_RS08270	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SULPSESMR1_RS08280	COG0840	transmembrane signaling receptor activity
SULPSESMR1_RS08285	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SULPSESMR1_RS08290	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SULPSESMR1_RS08405	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS08415	COG0482	sulfurtransferase activity
SULPSESMR1_RS08420	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SULPSESMR1_RS08425	COG3494	Protein of unknown function (DUF1009)
SULPSESMR1_RS08430	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SULPSESMR1_RS08435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SULPSESMR1_RS08445	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SULPSESMR1_RS08450	COG0750	zinc metalloprotease
SULPSESMR1_RS08455	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SULPSESMR1_RS08465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SULPSESMR1_RS08470	COG0233	cytoplasmic translational termination
SULPSESMR1_RS08475	COG0528	UMP kinase activity
SULPSESMR1_RS08480	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SULPSESMR1_RS08490	COG0601	transmembrane transport
SULPSESMR1_RS08495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS08500	COG4172	Belongs to the ABC transporter superfamily
SULPSESMR1_RS08510	COG1196	nuclear chromosome segregation
SULPSESMR1_RS08510	COG0741	lytic transglycosylase activity
SULPSESMR1_RS08510	COG0739	heme binding
SULPSESMR1_RS08515	COG0629	single-stranded DNA binding
SULPSESMR1_RS08520	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SULPSESMR1_RS08525	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SULPSESMR1_RS08540	COG4974	Belongs to the 'phage' integrase family
SULPSESMR1_RS08545	COG4536	flavin adenine dinucleotide binding
SULPSESMR1_RS08565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SULPSESMR1_RS08590	COG1238	metal cluster binding
SULPSESMR1_RS08605	COG0010	Belongs to the arginase family
SULPSESMR1_RS08610	COG2423	ornithine cyclodeaminase activity
SULPSESMR1_RS08635	COG2099	Precorrin-6x reductase
SULPSESMR1_RS08640	COG0698	ribose 5-phosphate isomerase
SULPSESMR1_RS08645	COG2814	Major facilitator Superfamily
SULPSESMR1_RS08665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SULPSESMR1_RS08670	COG0215	cysteine-tRNA ligase activity
SULPSESMR1_RS08680	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
SULPSESMR1_RS08710	COG0019	diaminopimelate decarboxylase activity
SULPSESMR1_RS08715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SULPSESMR1_RS08730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SULPSESMR1_RS08750	COG1278	Cold shock
SULPSESMR1_RS08755	COG0259	pyridoxamine-phosphate oxidase activity
SULPSESMR1_RS08760	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SULPSESMR1_RS08770	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SULPSESMR1_RS08785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SULPSESMR1_RS08805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SULPSESMR1_RS08810	COG0134	indole-3-glycerol-phosphate synthase activity
SULPSESMR1_RS08815	COG0315	cyclic pyranopterin monophosphate synthase activity
SULPSESMR1_RS08820	COG0303	'Molybdopterin
SULPSESMR1_RS08825	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SULPSESMR1_RS08835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SULPSESMR1_RS08840	COG0372	Belongs to the citrate synthase family
SULPSESMR1_RS08855	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS08860	COG3088	subunit of a heme lyase
SULPSESMR1_RS08865	COG1138	Cytochrome C-type biogenesis protein
SULPSESMR1_RS08880	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
SULPSESMR1_RS08885	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SULPSESMR1_RS08890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SULPSESMR1_RS08920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SULPSESMR1_RS08965	COG0418	dihydroorotase activity
SULPSESMR1_RS08970	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SULPSESMR1_RS08975	COG0305	Participates in initiation and elongation during chromosome replication
SULPSESMR1_RS08980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SULPSESMR1_RS08985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SULPSESMR1_RS08990	COG1127	ABC transporter
SULPSESMR1_RS09015	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SULPSESMR1_RS09030	COG4221	oxidoreductase activity
SULPSESMR1_RS09035	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SULPSESMR1_RS09040	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SULPSESMR1_RS09045	COG1388	LysM domain
SULPSESMR1_RS09045	COG0739	heme binding
SULPSESMR1_RS09060	COG0805	protein transport
SULPSESMR1_RS09065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SULPSESMR1_RS09070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SULPSESMR1_RS09075	COG2378	regulation of single-species biofilm formation
SULPSESMR1_RS09090	COG3842	ATPase activity
SULPSESMR1_RS09095	COG4335	DNA alkylation repair
SULPSESMR1_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS09110	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SULPSESMR1_RS09125	COG0513	Belongs to the DEAD box helicase family
SULPSESMR1_RS09130	COG1764	response to oxidative stress
SULPSESMR1_RS09140	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SULPSESMR1_RS09150	COG1007	ATP synthesis coupled electron transport
SULPSESMR1_RS09165	COG0713	ATP synthesis coupled electron transport
SULPSESMR1_RS09180	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULPSESMR1_RS09185	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SULPSESMR1_RS09235	COG0649	NAD binding
SULPSESMR1_RS09240	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULPSESMR1_RS09245	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULPSESMR1_RS09275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SULPSESMR1_RS09280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULPSESMR1_RS09295	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS09315	COG0546	phosphoglycolate phosphatase activity
SULPSESMR1_RS09320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SULPSESMR1_RS09325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SULPSESMR1_RS09345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SULPSESMR1_RS09350	COG1519	Transferase
SULPSESMR1_RS09360	COG1473	amidohydrolase
SULPSESMR1_RS09365	COG1473	amidohydrolase
SULPSESMR1_RS09370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULPSESMR1_RS09375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULPSESMR1_RS09380	COG4172	Belongs to the ABC transporter superfamily
SULPSESMR1_RS09390	COG0601	transmembrane transport
SULPSESMR1_RS09395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS09410	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
SULPSESMR1_RS09435	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SULPSESMR1_RS09445	COG0308	aminopeptidase N
SULPSESMR1_RS09450	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS09480	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SULPSESMR1_RS09505	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
SULPSESMR1_RS09545	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SULPSESMR1_RS09550	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SULPSESMR1_RS09555	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SULPSESMR1_RS09560	COG0849	cell division
SULPSESMR1_RS09565	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SULPSESMR1_RS09570	COG1181	Belongs to the D-alanine--D-alanine ligase family
SULPSESMR1_RS09575	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SULPSESMR1_RS09595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SULPSESMR1_RS09600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SULPSESMR1_RS09615	COG2081	HI0933 family
SULPSESMR1_RS09620	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SULPSESMR1_RS09625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SULPSESMR1_RS09635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SULPSESMR1_RS09650	COG0275	rRNA processing
SULPSESMR1_RS09655	COG2001	Belongs to the MraZ family
SULPSESMR1_RS09660	COG0489	protein tyrosine kinase activity
SULPSESMR1_RS09675	COG0210	DNA helicase
SULPSESMR1_RS09685	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SULPSESMR1_RS09690	COG0346	lactoylglutathione lyase activity
SULPSESMR1_RS09705	COG2115	Belongs to the xylose isomerase family
SULPSESMR1_RS09715	COG0673	inositol 2-dehydrogenase activity
SULPSESMR1_RS09720	COG1129	ABC transporter
SULPSESMR1_RS09725	COG1172	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS09740	COG0131	Imidazoleglycerol-phosphate dehydratase
SULPSESMR1_RS09745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SULPSESMR1_RS09760	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SULPSESMR1_RS09765	COG0107	imidazoleglycerol-phosphate synthase activity
SULPSESMR1_RS09770	COG0140	phosphoribosyl-ATP diphosphatase activity
SULPSESMR1_RS09775	COG1832	CoA-binding protein
SULPSESMR1_RS09785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SULPSESMR1_RS09795	COG2132	Multicopper oxidase
SULPSESMR1_RS09820	COG2873	o-acetylhomoserine
SULPSESMR1_RS09855	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SULPSESMR1_RS09860	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SULPSESMR1_RS09865	COG1329	Transcriptional regulator
SULPSESMR1_RS09870	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SULPSESMR1_RS09875	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SULPSESMR1_RS09905	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SULPSESMR1_RS09905	COG1793	dna ligase
SULPSESMR1_RS09920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SULPSESMR1_RS09940	COG0564	pseudouridine synthase activity
SULPSESMR1_RS09985	COG1741	Belongs to the pirin family
SULPSESMR1_RS10010	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SULPSESMR1_RS10165	COG1250	3-hydroxyacyl-CoA dehydrogenase
SULPSESMR1_RS10165	COG0824	Thioesterase
SULPSESMR1_RS10175	COG3246	L-lysine catabolic process to acetate
SULPSESMR1_RS10185	COG0667	Aldo Keto reductase
SULPSESMR1_RS10195	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SULPSESMR1_RS10200	COG0840	transmembrane signaling receptor activity
SULPSESMR1_RS10225	COG1280	lysine exporter protein (LysE YggA)
SULPSESMR1_RS10235	COG1741	Belongs to the pirin family
SULPSESMR1_RS10290	COG1522	sequence-specific DNA binding
SULPSESMR1_RS10310	COG0483	inositol monophosphate 1-phosphatase activity
SULPSESMR1_RS10315	COG2130	NADP-dependent
SULPSESMR1_RS10320	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS10345	COG0525	valine-tRNA ligase activity
SULPSESMR1_RS10360	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SULPSESMR1_RS10365	COG1132	(ABC) transporter
SULPSESMR1_RS10375	COG0354	folic acid binding
SULPSESMR1_RS10385	COG1574	metal-dependent hydrolase with the TIM-barrel fold
SULPSESMR1_RS10390	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS10400	COG0601	transmembrane transport
SULPSESMR1_RS10405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS10410	COG0444	Belongs to the ABC transporter superfamily
SULPSESMR1_RS10415	COG4608	Belongs to the ABC transporter superfamily
SULPSESMR1_RS10420	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SULPSESMR1_RS10430	COG1492	cobalamin metabolic process
SULPSESMR1_RS10445	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SULPSESMR1_RS10490	COG0270	DNA (cytosine-5-)-methyltransferase activity
SULPSESMR1_RS10550	COG0586	Pfam SNARE associated Golgi protein
SULPSESMR1_RS10560	COG1597	lipid kinase activity
SULPSESMR1_RS10565	COG3386	PFAM SMP-30 Gluconolaconase
SULPSESMR1_RS10570	COG0800	Aldolase
SULPSESMR1_RS10575	COG3734	2-keto-3-deoxy-galactonokinase
SULPSESMR1_RS10580	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS10585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SULPSESMR1_RS10590	COG0527	aspartate kinase activity
SULPSESMR1_RS10610	COG0725	ABC transporter, periplasmic molybdate-binding protein
SULPSESMR1_RS10615	COG4149	molybdate abc transporter
SULPSESMR1_RS10620	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SULPSESMR1_RS10640	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SULPSESMR1_RS10655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SULPSESMR1_RS10675	COG0612	Peptidase, M16
SULPSESMR1_RS10685	COG3346	SURF1 family
SULPSESMR1_RS10695	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
SULPSESMR1_RS10705	COG0109	protoheme IX farnesyltransferase activity
SULPSESMR1_RS10715	COG0312	modulator of DNA gyrase
SULPSESMR1_RS10720	COG0758	DNA mediated transformation
SULPSESMR1_RS10725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SULPSESMR1_RS10725	COG1754	DNA topoisomerase type I activity
SULPSESMR1_RS10735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SULPSESMR1_RS10760	COG4964	Belongs to the GSP D family
SULPSESMR1_RS10810	COG1201	RNA secondary structure unwinding
SULPSESMR1_RS10825	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SULPSESMR1_RS10830	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SULPSESMR1_RS10840	COG0024	Methionine aminopeptidase
SULPSESMR1_RS10845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULPSESMR1_RS10850	COG0037	tRNA processing
SULPSESMR1_RS10860	COG2885	chlorophyll binding
SULPSESMR1_RS10865	COG0823	Involved in the tonB-independent uptake of proteins
SULPSESMR1_RS10885	COG0824	Thioesterase
SULPSESMR1_RS10895	COG2255	four-way junction helicase activity
SULPSESMR1_RS10900	COG0632	four-way junction helicase activity
SULPSESMR1_RS10940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SULPSESMR1_RS10955	COG1183	phosphatidylcholine synthase activity
SULPSESMR1_RS10960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SULPSESMR1_RS10965	COG1953	Uracil, thiamine, allantoin
SULPSESMR1_RS10970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SULPSESMR1_RS10980	COG3768	UPF0283 membrane protein
SULPSESMR1_RS10990	COG3106	COG3106 Predicted ATPase
SULPSESMR1_RS10995	COG0101	tRNA pseudouridine synthase activity
SULPSESMR1_RS11010	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SULPSESMR1_RS11015	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
SULPSESMR1_RS11035	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
SULPSESMR1_RS11040	COG2986	histidine ammonia-lyase
SULPSESMR1_RS11045	COG1228	amidohydrolase
SULPSESMR1_RS11140	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS11170	COG4608	Belongs to the ABC transporter superfamily
SULPSESMR1_RS11175	COG0747	negative chemotaxis
SULPSESMR1_RS11180	COG0601	transmembrane transport
SULPSESMR1_RS11185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS11190	COG0405	Gamma-glutamyltransferase
SULPSESMR1_RS11200	COG0730	response to heat
SULPSESMR1_RS11205	COG2186	Transcriptional regulator
SULPSESMR1_RS11215	COG0012	GTP binding
SULPSESMR1_RS11225	COG0159	tryptophan synthase activity
SULPSESMR1_RS11245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SULPSESMR1_RS11255	COG0193	aminoacyl-tRNA hydrolase activity
SULPSESMR1_RS11275	COG0133	tryptophan synthase activity
SULPSESMR1_RS11280	COG0135	phosphoribosylanthranilate isomerase activity
SULPSESMR1_RS11290	COG0776	regulation of translation
SULPSESMR1_RS11295	COG0539	negative regulation of cytoplasmic translation
SULPSESMR1_RS11300	COG0667	Aldo Keto reductase
SULPSESMR1_RS11305	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SULPSESMR1_RS11315	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SULPSESMR1_RS11320	COG1012	belongs to the aldehyde dehydrogenase family
SULPSESMR1_RS11325	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SULPSESMR1_RS11335	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SULPSESMR1_RS11340	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SULPSESMR1_RS11345	COG1253	flavin adenine dinucleotide binding
SULPSESMR1_RS11350	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SULPSESMR1_RS11355	COG1702	phosphate starvation-inducible protein PhoH
SULPSESMR1_RS11365	COG2885	chlorophyll binding
SULPSESMR1_RS11370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SULPSESMR1_RS11390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SULPSESMR1_RS11395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SULPSESMR1_RS11400	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SULPSESMR1_RS11410	COG1047	Peptidyl-prolyl cis-trans
SULPSESMR1_RS11420	COG2267	carboxylic ester hydrolase activity
SULPSESMR1_RS11435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SULPSESMR1_RS11455	COG4948	Mandelate Racemase Muconate Lactonizing
SULPSESMR1_RS11470	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS11475	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SULPSESMR1_RS11480	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS11505	COG0737	Belongs to the 5'-nucleotidase family
SULPSESMR1_RS11525	COG0534	Mate efflux family protein
SULPSESMR1_RS11550	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS11560	COG0625	glutathione transferase activity
SULPSESMR1_RS11565	COG0183	Belongs to the thiolase family
SULPSESMR1_RS11575	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS11575	COG1250	3-hydroxyacyl-CoA dehydrogenase
SULPSESMR1_RS11580	COG3239	Fatty acid desaturase
SULPSESMR1_RS11585	COG0471	metal ion transport
SULPSESMR1_RS11585	COG3273	potassium ion transport
SULPSESMR1_RS11595	COG0697	spore germination
SULPSESMR1_RS11600	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS11615	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SULPSESMR1_RS11620	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SULPSESMR1_RS11625	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SULPSESMR1_RS11640	COG0281	malic enzyme
SULPSESMR1_RS11640	COG0280	phosphate acetyltransferase
SULPSESMR1_RS11650	COG3237	CsbD-like
SULPSESMR1_RS11660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SULPSESMR1_RS11685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SULPSESMR1_RS11690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SULPSESMR1_RS11700	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
SULPSESMR1_RS11700	COG0028	Belongs to the TPP enzyme family
SULPSESMR1_RS11710	COG0431	NADPH-dependent FMN reductase
SULPSESMR1_RS11720	COG1435	thymidine kinase activity
SULPSESMR1_RS11730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SULPSESMR1_RS11750	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SULPSESMR1_RS11760	COG1496	oxidoreductase activity
SULPSESMR1_RS11770	COG1522	sequence-specific DNA binding
SULPSESMR1_RS11775	COG0492	ferredoxin-NADP+ reductase activity
SULPSESMR1_RS11790	COG2046	Belongs to the sulfate adenylyltransferase family
SULPSESMR1_RS11790	COG0529	Catalyzes the synthesis of activated sulfate
SULPSESMR1_RS11800	COG0384	phenazine biosynthesis protein PhzF
SULPSESMR1_RS11810	COG0071	Belongs to the small heat shock protein (HSP20) family
SULPSESMR1_RS11820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SULPSESMR1_RS11825	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SULPSESMR1_RS11830	COG3454	Phosphonate metabolism
SULPSESMR1_RS11855	COG0459	protein refolding
SULPSESMR1_RS11860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SULPSESMR1_RS11880	COG1227	inorganic diphosphatase activity
SULPSESMR1_RS11890	COG2030	dehydratase
SULPSESMR1_RS11895	COG0196	riboflavin kinase activity
SULPSESMR1_RS11900	COG2983	Belongs to the UPF0260 family
SULPSESMR1_RS11910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SULPSESMR1_RS11930	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SULPSESMR1_RS11935	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SULPSESMR1_RS11940	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SULPSESMR1_RS11945	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SULPSESMR1_RS11950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SULPSESMR1_RS11955	COG0235	Class ii aldolase
SULPSESMR1_RS11965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SULPSESMR1_RS11990	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
SULPSESMR1_RS12005	COG0287	Prephenate dehydrogenase
SULPSESMR1_RS12010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SULPSESMR1_RS12015	COG1573	uracil-dna glycosylase
SULPSESMR1_RS12020	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SULPSESMR1_RS12025	COG2818	Glycosylase
SULPSESMR1_RS12030	COG2200	EAL domain
SULPSESMR1_RS12040	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS12045	COG1309	transcriptional regulator
SULPSESMR1_RS12070	COG0142	geranyltranstransferase activity
SULPSESMR1_RS12075	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SULPSESMR1_RS12085	COG0640	Transcriptional regulator
SULPSESMR1_RS12100	COG0789	Transcriptional regulator
SULPSESMR1_RS12110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SULPSESMR1_RS12125	COG0667	Aldo Keto reductase
SULPSESMR1_RS12130	COG0303	'Molybdopterin
SULPSESMR1_RS12140	COG0746	molybdenum cofactor guanylyltransferase activity
SULPSESMR1_RS12180	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS12185	COG0009	L-threonylcarbamoyladenylate synthase
SULPSESMR1_RS12200	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS12215	COG1678	Uncharacterized ACR, COG1678
SULPSESMR1_RS12235	COG0521	Mo-molybdopterin cofactor biosynthetic process
SULPSESMR1_RS12240	COG1280	lysine exporter protein (LysE YggA)
SULPSESMR1_RS12250	COG1573	uracil-dna glycosylase
SULPSESMR1_RS12255	COG0540	Belongs to the ATCase OTCase family
SULPSESMR1_RS12270	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SULPSESMR1_RS12275	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SULPSESMR1_RS12290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SULPSESMR1_RS12295	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SULPSESMR1_RS12300	COG2885	chlorophyll binding
SULPSESMR1_RS12310	COG0314	molybdopterin synthase activity
SULPSESMR1_RS12320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SULPSESMR1_RS12330	COG0322	excinuclease ABC activity
SULPSESMR1_RS12350	COG0842	Transport permease protein
SULPSESMR1_RS12355	COG1131	(ABC) transporter
SULPSESMR1_RS12365	COG0697	spore germination
SULPSESMR1_RS12370	COG0604	alcohol dehydrogenase
SULPSESMR1_RS12370	COG3321	synthase
SULPSESMR1_RS12370	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS12375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SULPSESMR1_RS12380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SULPSESMR1_RS12395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SULPSESMR1_RS12415	COG0747	negative chemotaxis
SULPSESMR1_RS12420	COG0601	transmembrane transport
SULPSESMR1_RS12425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS12430	COG4172	Belongs to the ABC transporter superfamily
SULPSESMR1_RS12435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SULPSESMR1_RS12460	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SULPSESMR1_RS12460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SULPSESMR1_RS12470	COG0432	Pfam Uncharacterised protein family UPF0047
SULPSESMR1_RS12485	COG4221	oxidoreductase activity
SULPSESMR1_RS12495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SULPSESMR1_RS12500	COG0358	DNA primase activity
SULPSESMR1_RS12515	COG0446	pyridine nucleotide-disulphide oxidoreductase
SULPSESMR1_RS12515	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SULPSESMR1_RS12525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULPSESMR1_RS12530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SULPSESMR1_RS12630	COG4191	Histidine kinase
SULPSESMR1_RS12635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULPSESMR1_RS12645	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SULPSESMR1_RS12650	COG0594	ribonuclease P activity
SULPSESMR1_RS12655	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SULPSESMR1_RS12660	COG0037	tRNA processing
SULPSESMR1_RS12665	COG5001	Diguanylate cyclase
SULPSESMR1_RS12670	COG0706	membrane insertase activity
SULPSESMR1_RS12680	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SULPSESMR1_RS12685	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SULPSESMR1_RS12705	COG1126	abc transporter atp-binding protein
SULPSESMR1_RS12710	COG0765	amino acid transport
SULPSESMR1_RS12715	COG4597	amino acid ABC transporter
SULPSESMR1_RS12720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SULPSESMR1_RS12730	COG0546	phosphoglycolate phosphatase activity
SULPSESMR1_RS12735	COG0564	pseudouridine synthase activity
SULPSESMR1_RS12740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SULPSESMR1_RS12745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SULPSESMR1_RS12750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SULPSESMR1_RS12765	COG0203	ribosomal protein L17
SULPSESMR1_RS12770	COG0202	RNA polymerase activity
SULPSESMR1_RS12775	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SULPSESMR1_RS12780	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SULPSESMR1_RS12785	COG0563	adenylate kinase activity
SULPSESMR1_RS12790	COG0201	protein transport
SULPSESMR1_RS12795	COG0200	Binds to the 23S rRNA
SULPSESMR1_RS12800	COG1841	ribosomal large subunit assembly
SULPSESMR1_RS12805	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SULPSESMR1_RS12810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SULPSESMR1_RS12815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SULPSESMR1_RS12820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SULPSESMR1_RS12825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SULPSESMR1_RS12830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SULPSESMR1_RS12835	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SULPSESMR1_RS12840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SULPSESMR1_RS12845	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SULPSESMR1_RS12850	COG0255	Belongs to the universal ribosomal protein uL29 family
SULPSESMR1_RS12855	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS12875	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SULPSESMR1_RS12880	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SULPSESMR1_RS12885	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SULPSESMR1_RS12890	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SULPSESMR1_RS12895	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SULPSESMR1_RS12900	COG0089	rRNA binding
SULPSESMR1_RS12905	COG0088	Forms part of the polypeptide exit tunnel
SULPSESMR1_RS12910	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SULPSESMR1_RS12915	COG0051	transcription antitermination factor activity, RNA binding
SULPSESMR1_RS12925	COG0306	phosphate transporter
SULPSESMR1_RS12935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SULPSESMR1_RS12940	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SULPSESMR1_RS12945	COG0049	tRNA binding
SULPSESMR1_RS12950	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SULPSESMR1_RS12960	COG0697	spore germination
SULPSESMR1_RS12970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SULPSESMR1_RS12975	COG0085	RNA polymerase activity
SULPSESMR1_RS12980	COG0222	ribosome binding
SULPSESMR1_RS12985	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SULPSESMR1_RS12990	COG0081	regulation of translation
SULPSESMR1_RS12995	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SULPSESMR1_RS13000	COG0250	Participates in transcription elongation, termination and antitermination
SULPSESMR1_RS13025	COG0662	Cupin 2, conserved barrel domain protein
SULPSESMR1_RS13030	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SULPSESMR1_RS13040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SULPSESMR1_RS13040	COG2124	cytochrome p450
SULPSESMR1_RS13045	COG0501	Belongs to the peptidase M48B family
SULPSESMR1_RS13055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SULPSESMR1_RS13065	COG0300	oxidoreductase activity
SULPSESMR1_RS13075	COG2096	Adenosyltransferase
SULPSESMR1_RS13095	COG1250	3-hydroxyacyl-CoA dehydrogenase
SULPSESMR1_RS13115	COG1660	Displays ATPase and GTPase activities
SULPSESMR1_RS13120	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SULPSESMR1_RS13125	COG2205	protein histidine kinase activity
SULPSESMR1_RS13130	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS13135	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SULPSESMR1_RS13150	COG1396	sequence-specific DNA binding
SULPSESMR1_RS13175	COG1381	Involved in DNA repair and RecF pathway recombination
SULPSESMR1_RS13185	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SULPSESMR1_RS13190	COG0571	ribonuclease III activity
SULPSESMR1_RS13195	COG0681	Belongs to the peptidase S26 family
SULPSESMR1_RS13200	COG0736	holo-[acyl-carrier-protein] synthase activity
SULPSESMR1_RS13210	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SULPSESMR1_RS13220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SULPSESMR1_RS13225	COG1758	RNA polymerase activity
SULPSESMR1_RS13230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SULPSESMR1_RS13240	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SULPSESMR1_RS13260	COG0328	RNA-DNA hybrid ribonuclease activity
SULPSESMR1_RS13270	COG2860	membrane
SULPSESMR1_RS13280	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SULPSESMR1_RS13285	COG0242	peptide deformylase activity
SULPSESMR1_RS13290	COG0242	peptide deformylase activity
SULPSESMR1_RS13295	COG0242	peptide deformylase activity
SULPSESMR1_RS13300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SULPSESMR1_RS13310	COG0435	Glutathione S-transferase
SULPSESMR1_RS13325	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SULPSESMR1_RS13365	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SULPSESMR1_RS13370	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SULPSESMR1_RS13380	COG0356	it plays a direct role in the translocation of protons across the membrane
SULPSESMR1_RS13390	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS13415	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SULPSESMR1_RS13425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SULPSESMR1_RS13440	COG0228	four-way junction DNA binding
SULPSESMR1_RS13450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SULPSESMR1_RS13470	COG0336	Belongs to the RNA methyltransferase TrmD family
SULPSESMR1_RS13475	COG0300	oxidoreductase activity
SULPSESMR1_RS13490	COG0335	large ribosomal subunit rRNA binding
SULPSESMR1_RS13495	COG0254	rRNA binding
SULPSESMR1_RS13505	COG0489	protein tyrosine kinase activity
SULPSESMR1_RS13505	COG2151	metal-sulfur cluster biosynthetic enzyme
SULPSESMR1_RS13515	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SULPSESMR1_RS13535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SULPSESMR1_RS13545	COG0747	negative chemotaxis
SULPSESMR1_RS13555	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SULPSESMR1_RS13590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULPSESMR1_RS13625	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SULPSESMR1_RS13630	COG0181	hydroxymethylbilane synthase activity
SULPSESMR1_RS13640	COG0408	coproporphyrinogen oxidase activity
SULPSESMR1_RS13645	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS13650	COG2813	Specifically methylates the guanine in position
SULPSESMR1_RS13655	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SULPSESMR1_RS13665	COG1686	Belongs to the peptidase S11 family
SULPSESMR1_RS13670	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS13680	COG4172	Belongs to the ABC transporter superfamily
SULPSESMR1_RS13685	COG4239	(ABC) transporter, permease
SULPSESMR1_RS13690	COG4174	ABC transporter (Permease)
SULPSESMR1_RS13695	COG4166	transmembrane transport
SULPSESMR1_RS13705	COG1605	Chorismate mutase
SULPSESMR1_RS13705	COG0077	Prephenate dehydratase
SULPSESMR1_RS13725	COG0737	Belongs to the 5'-nucleotidase family
SULPSESMR1_RS13750	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SULPSESMR1_RS13755	COG0019	diaminopimelate decarboxylase activity
SULPSESMR1_RS13810	COG2099	Precorrin-6x reductase
SULPSESMR1_RS13825	COG2875	Belongs to the precorrin methyltransferase family
SULPSESMR1_RS13830	COG1797	cobyrinic acid a,c-diamide synthase activity
SULPSESMR1_RS13835	COG1648	precorrin-2 dehydrogenase activity
SULPSESMR1_RS13835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SULPSESMR1_RS13875	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS13910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULPSESMR1_RS13925	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
SULPSESMR1_RS13925	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS13945	COG0459	protein refolding
SULPSESMR1_RS13950	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SULPSESMR1_RS13955	COG3047	cAMP biosynthetic process
SULPSESMR1_RS13975	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SULPSESMR1_RS14020	COG0697	spore germination
SULPSESMR1_RS14055	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
SULPSESMR1_RS14060	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SULPSESMR1_RS14065	COG0069	glutamate synthase activity
SULPSESMR1_RS14070	COG0702	epimerase
SULPSESMR1_RS14075	COG1733	regulation of RNA biosynthetic process
SULPSESMR1_RS14095	COG0284	orotidine-5'-phosphate decarboxylase activity
SULPSESMR1_RS14105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SULPSESMR1_RS14125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SULPSESMR1_RS14130	COG0625	glutathione transferase activity
SULPSESMR1_RS14135	COG1178	ABC-type Fe3 transport system permease component
SULPSESMR1_RS14175	COG0559	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS14200	COG4191	Histidine kinase
SULPSESMR1_RS14220	COG0443	Heat shock 70 kDa protein
SULPSESMR1_RS14230	COG3383	formate dehydrogenase (NAD+) activity
SULPSESMR1_RS14245	COG0625	glutathione transferase activity
SULPSESMR1_RS14255	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS14280	COG1595	DNA-templated transcription, initiation
SULPSESMR1_RS14285	COG3806	Anti-sigma factor
SULPSESMR1_RS14295	COG1012	belongs to the aldehyde dehydrogenase family
SULPSESMR1_RS14315	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
SULPSESMR1_RS14320	COG3257	ureidoglycine aminohydrolase activity
SULPSESMR1_RS14330	COG2351	hydroxyisourate hydrolase activity
SULPSESMR1_RS14335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SULPSESMR1_RS14340	COG1321	iron dependent repressor
SULPSESMR1_RS14340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SULPSESMR1_RS14345	COG1121	(ABC) transporter
SULPSESMR1_RS14350	COG0803	Belongs to the bacterial solute-binding protein 9 family
SULPSESMR1_RS14355	COG2205	protein histidine kinase activity
SULPSESMR1_RS14360	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS14370	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SULPSESMR1_RS14375	COG1012	belongs to the aldehyde dehydrogenase family
SULPSESMR1_RS14380	COG0612	Peptidase, M16
SULPSESMR1_RS14385	COG0612	Peptidase, M16
SULPSESMR1_RS14395	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SULPSESMR1_RS14400	COG0138	bifunctional purine biosynthesis protein purh
SULPSESMR1_RS14425	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SULPSESMR1_RS14430	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SULPSESMR1_RS14435	COG3698	Phosphodiester glycosidase
SULPSESMR1_RS14440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SULPSESMR1_RS14455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SULPSESMR1_RS14465	COG1115	amino acid carrier protein
SULPSESMR1_RS14470	COG1185	polyribonucleotide nucleotidyltransferase activity
SULPSESMR1_RS14475	COG1902	pentaerythritol trinitrate reductase activity
SULPSESMR1_RS14490	COG0450	alkyl hydroperoxide reductase
SULPSESMR1_RS14510	COG0564	pseudouridine synthase activity
SULPSESMR1_RS14590	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
SULPSESMR1_RS14600	COG1674	ftsk spoiiie
SULPSESMR1_RS14605	COG0436	Aminotransferase
SULPSESMR1_RS14610	COG0154	amidase activity
SULPSESMR1_RS14615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SULPSESMR1_RS14620	COG2835	tetraacyldisaccharide 4'-kinase activity
SULPSESMR1_RS14625	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SULPSESMR1_RS14640	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS14655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SULPSESMR1_RS14670	COG0495	leucyl-tRNA aminoacylation
SULPSESMR1_RS14695	COG0493	'glutamate synthase
SULPSESMR1_RS14695	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
SULPSESMR1_RS14735	COG0312	modulator of DNA gyrase
SULPSESMR1_RS14755	COG1663	tetraacyldisaccharide 4'-kinase activity
SULPSESMR1_RS14765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SULPSESMR1_RS14775	COG1194	a g-specific adenine glycosylase
SULPSESMR1_RS14780	COG3239	Fatty acid desaturase
SULPSESMR1_RS14790	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SULPSESMR1_RS14795	COG1902	pentaerythritol trinitrate reductase activity
SULPSESMR1_RS14795	COG0446	pyridine nucleotide-disulphide oxidoreductase
SULPSESMR1_RS14830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SULPSESMR1_RS14840	COG0288	reversible hydration of carbon dioxide
SULPSESMR1_RS14855	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SULPSESMR1_RS14860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SULPSESMR1_RS14885	COG2808	Putative FMN-binding domain
SULPSESMR1_RS14895	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
SULPSESMR1_RS14900	COG1178	ABC-type Fe3 transport system permease component
SULPSESMR1_RS14905	COG4143	(ABC) transporter
SULPSESMR1_RS14910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SULPSESMR1_RS14920	COG0697	spore germination
SULPSESMR1_RS14935	COG3051	citrate lyase alpha subunit
SULPSESMR1_RS14945	COG1846	Transcriptional regulator
SULPSESMR1_RS14950	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS14955	COG1722	exodeoxyribonuclease VII activity
SULPSESMR1_RS14960	COG0142	geranyltranstransferase activity
SULPSESMR1_RS14965	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SULPSESMR1_RS14995	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS15005	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS15020	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SULPSESMR1_RS15025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SULPSESMR1_RS15065	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS15075	COG1309	transcriptional regulator
SULPSESMR1_RS15080	COG2080	2 iron, 2 sulfur cluster binding
SULPSESMR1_RS15085	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
SULPSESMR1_RS15090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SULPSESMR1_RS15095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SULPSESMR1_RS15135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SULPSESMR1_RS15145	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SULPSESMR1_RS15155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SULPSESMR1_RS15175	COG1968	undecaprenyl-diphosphatase activity
SULPSESMR1_RS15195	COG3396	Phenylacetate-CoA oxygenase
SULPSESMR1_RS15200	COG3460	Phenylacetate-CoA oxygenase
SULPSESMR1_RS15205	COG3396	Phenylacetate-CoA oxygenase
SULPSESMR1_RS15210	COG2151	metal-sulfur cluster biosynthetic enzyme
SULPSESMR1_RS15215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SULPSESMR1_RS15220	COG2030	dehydratase
SULPSESMR1_RS15220	COG1012	belongs to the aldehyde dehydrogenase family
SULPSESMR1_RS15225	COG3327	negative regulation of DNA-templated transcription, initiation
SULPSESMR1_RS15230	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SULPSESMR1_RS15235	COG0517	IMP dehydrogenase activity
SULPSESMR1_RS15235	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SULPSESMR1_RS15250	COG1137	ATPase activity
SULPSESMR1_RS15255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SULPSESMR1_RS15260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SULPSESMR1_RS15285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SULPSESMR1_RS15290	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SULPSESMR1_RS15300	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SULPSESMR1_RS15305	COG1218	3'(2'),5'-bisphosphate nucleotidase
SULPSESMR1_RS15325	COG0443	Heat shock 70 kDa protein
SULPSESMR1_RS15330	COG0484	heat shock protein binding
SULPSESMR1_RS15335	COG2003	Belongs to the UPF0758 family
SULPSESMR1_RS15350	COG0653	protein targeting
SULPSESMR1_RS15355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SULPSESMR1_RS15360	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SULPSESMR1_RS15365	COG0494	nUDIX hydrolase
SULPSESMR1_RS15380	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SULPSESMR1_RS15395	COG0779	Required for maturation of 30S ribosomal subunits
SULPSESMR1_RS15410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SULPSESMR1_RS15420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SULPSESMR1_RS15430	COG1040	competence protein
SULPSESMR1_RS15435	COG2226	methyltransferase
SULPSESMR1_RS15460	COG3034	peptidoglycan biosynthetic process
SULPSESMR1_RS15465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SULPSESMR1_RS15475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SULPSESMR1_RS15485	COG0443	Heat shock 70 kDa protein
SULPSESMR1_RS15500	COG0123	including yeast histone deacetylase and acetoin utilization protein
SULPSESMR1_RS15510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS15530	COG0662	Cupin 2, conserved barrel domain protein
SULPSESMR1_RS15535	COG3191	aminopeptidase activity
SULPSESMR1_RS15545	COG3474	cytochrome
SULPSESMR1_RS15565	COG2116	formate transmembrane transporter activity
SULPSESMR1_RS15580	COG0784	Response regulator, receiver
SULPSESMR1_RS15605	COG1132	(ABC) transporter
SULPSESMR1_RS15610	COG1132	(ABC) transporter
SULPSESMR1_RS15615	COG0617	tRNA 3'-terminal CCA addition
SULPSESMR1_RS15620	COG0494	nUDIX hydrolase
SULPSESMR1_RS15630	COG0494	nUDIX hydrolase
SULPSESMR1_RS15635	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS15645	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS15650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SULPSESMR1_RS15655	COG0137	argininosuccinate synthase activity
SULPSESMR1_RS15665	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SULPSESMR1_RS15670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SULPSESMR1_RS15675	COG0281	malic enzyme
SULPSESMR1_RS15675	COG0280	phosphate acetyltransferase
SULPSESMR1_RS15680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SULPSESMR1_RS15685	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SULPSESMR1_RS15690	COG1420	regulation of RNA biosynthetic process
SULPSESMR1_RS15695	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SULPSESMR1_RS15700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SULPSESMR1_RS15705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SULPSESMR1_RS15715	COG1192	Involved in chromosome partitioning
SULPSESMR1_RS15720	COG0357	Ribosomal RNA small subunit methyltransferase G
SULPSESMR1_RS15725	COG0445	tRNA wobble uridine modification
SULPSESMR1_RS15730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SULPSESMR1_RS15735	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SULPSESMR1_RS15740	COG1981	membrane
SULPSESMR1_RS15745	COG0424	maF-like protein
SULPSESMR1_RS15750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SULPSESMR1_RS15755	COG0237	dephospho-CoA kinase activity
SULPSESMR1_RS15760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SULPSESMR1_RS15765	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
SULPSESMR1_RS15800	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SULPSESMR1_RS15810	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SULPSESMR1_RS15835	COG1074	ATP-dependent DNA helicase activity
SULPSESMR1_RS15845	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SULPSESMR1_RS15850	COG3178	'Phosphotransferase
SULPSESMR1_RS15870	COG1999	signal sequence binding
SULPSESMR1_RS15875	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
SULPSESMR1_RS15885	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
SULPSESMR1_RS15895	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SULPSESMR1_RS15920	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SULPSESMR1_RS15925	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SULPSESMR1_RS15955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SULPSESMR1_RS15965	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SULPSESMR1_RS15970	COG0268	Binds directly to 16S ribosomal RNA
SULPSESMR1_RS15980	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SULPSESMR1_RS15985	COG2226	methyltransferase
SULPSESMR1_RS15995	COG0183	Belongs to the thiolase family
SULPSESMR1_RS16000	COG1396	sequence-specific DNA binding
SULPSESMR1_RS16005	COG0156	8-amino-7-oxononanoate synthase activity
SULPSESMR1_RS16010	COG1063	alcohol dehydrogenase
SULPSESMR1_RS16020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SULPSESMR1_RS16025	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SULPSESMR1_RS16030	COG0560	Phosphoserine phosphatase
SULPSESMR1_RS16030	COG3830	Belongs to the UPF0237 family
SULPSESMR1_RS16045	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SULPSESMR1_RS16070	COG2171	N-acyltransferase activity
SULPSESMR1_RS16085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SULPSESMR1_RS16100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULPSESMR1_RS16105	COG2153	protein acetylation
SULPSESMR1_RS16120	COG2378	regulation of single-species biofilm formation
SULPSESMR1_RS16125	COG2951	lytic endotransglycosylase activity
SULPSESMR1_RS16145	COG3842	ATPase activity
SULPSESMR1_RS16150	COG0006	proline dipeptidase activity
SULPSESMR1_RS16175	COG3842	ATPase activity
SULPSESMR1_RS16180	COG1176	ABC-type spermidine putrescine transport system, permease component I
SULPSESMR1_RS16185	COG1177	transmembrane transport
SULPSESMR1_RS16190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULPSESMR1_RS16195	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SULPSESMR1_RS16220	COG4786	Flagellar basal body rod
SULPSESMR1_RS16225	COG1360	Flagellar Motor Protein
SULPSESMR1_RS16230	COG2271	Major facilitator Superfamily
SULPSESMR1_RS16235	COG1054	Belongs to the UPF0176 family
SULPSESMR1_RS16240	COG1335	isochorismatase
SULPSESMR1_RS16245	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SULPSESMR1_RS16260	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SULPSESMR1_RS16290	COG0514	ATP-dependent DNA helicase (RecQ)
SULPSESMR1_RS16300	COG3022	response to hydroperoxide
SULPSESMR1_RS16305	COG0784	Response regulator, receiver
SULPSESMR1_RS16305	COG5002	protein histidine kinase activity
SULPSESMR1_RS16305	COG2205	protein histidine kinase activity
SULPSESMR1_RS16310	COG2373	Large extracellular alpha-helical protein
SULPSESMR1_RS16315	COG4953	penicillin-binding protein 1C
SULPSESMR1_RS16335	COG0714	Associated with various cellular activities
SULPSESMR1_RS16345	COG3622	Belongs to the hyi family
SULPSESMR1_RS16355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SULPSESMR1_RS16355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SULPSESMR1_RS16370	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SULPSESMR1_RS16380	COG0793	Belongs to the peptidase S41A family
SULPSESMR1_RS16385	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS16405	COG0129	dihydroxy-acid dehydratase activity
SULPSESMR1_RS16420	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SULPSESMR1_RS16425	COG0285	dihydrofolate synthase activity
SULPSESMR1_RS16430	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
SULPSESMR1_RS16435	COG2271	Major facilitator Superfamily
SULPSESMR1_RS16440	COG0596	Alpha beta hydrolase
SULPSESMR1_RS16445	COG2423	ornithine cyclodeaminase activity
SULPSESMR1_RS16455	COG1671	Belongs to the UPF0178 family
SULPSESMR1_RS16465	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
SULPSESMR1_RS16470	COG0679	Auxin Efflux Carrier
SULPSESMR1_RS16490	COG2050	protein possibly involved in aromatic compounds catabolism
SULPSESMR1_RS16500	COG0791	NLP P60 protein
SULPSESMR1_RS16505	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SULPSESMR1_RS16510	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SULPSESMR1_RS16525	COG3214	Protein conserved in bacteria
SULPSESMR1_RS16530	COG1609	Transcriptional regulator
SULPSESMR1_RS16570	COG1476	TRANSCRIPTIONal
SULPSESMR1_RS16590	COG0655	NAD(P)H dehydrogenase (quinone) activity
SULPSESMR1_RS16615	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS16620	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS16625	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS16630	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS16635	COG2070	2-Nitropropane dioxygenase
SULPSESMR1_RS16710	COG2308	Evidence 4 Homologs of previously reported genes of
SULPSESMR1_RS16720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SULPSESMR1_RS16725	COG3485	protocatechuate 3,4-dioxygenase
SULPSESMR1_RS16730	COG3485	protocatechuate 3,4-dioxygenase
SULPSESMR1_RS16740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SULPSESMR1_RS16745	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS16750	COG0154	amidase activity
SULPSESMR1_RS16755	COG2957	Belongs to the agmatine deiminase family
SULPSESMR1_RS16760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SULPSESMR1_RS16770	COG0697	spore germination
SULPSESMR1_RS16775	COG0473	3-isopropylmalate dehydrogenase activity
SULPSESMR1_RS16790	COG0066	3-isopropylmalate dehydratase activity
SULPSESMR1_RS16800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SULPSESMR1_RS16805	COG3264	Mechanosensitive ion channel
SULPSESMR1_RS16805	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SULPSESMR1_RS16815	COG0799	negative regulation of ribosome biogenesis
SULPSESMR1_RS16820	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SULPSESMR1_RS16830	COG0277	FAD linked oxidase domain protein
SULPSESMR1_RS16835	COG0277	FAD linked oxidase domain protein
SULPSESMR1_RS16845	COG0247	lactate metabolic process
SULPSESMR1_RS16850	COG3591	Belongs to the peptidase S1B family
SULPSESMR1_RS16855	COG0071	Belongs to the small heat shock protein (HSP20) family
SULPSESMR1_RS16860	COG1012	belongs to the aldehyde dehydrogenase family
SULPSESMR1_RS16915	COG1376	ErfK ybiS ycfS ynhG family protein
SULPSESMR1_RS16935	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SULPSESMR1_RS16940	COG2897	thiosulfate sulfurtransferase activity
SULPSESMR1_RS16950	COG0004	ammonium transporteR
SULPSESMR1_RS16980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SULPSESMR1_RS16985	COG0251	oxidation-reduction process
SULPSESMR1_RS16990	COG0584	glycerophosphoryl diester phosphodiesterase
SULPSESMR1_RS17000	COG2154	pterin-4-alpha-carbinolamine dehydratase
SULPSESMR1_RS17005	COG0668	transmembrane transport
SULPSESMR1_RS17010	COG0678	peroxiredoxin activity
SULPSESMR1_RS17020	COG0742	ribosomal rna small subunit methyltransferase
SULPSESMR1_RS17030	COG0024	Methionine aminopeptidase
SULPSESMR1_RS17035	COG1489	DNA binding
SULPSESMR1_RS17040	COG1546	Belongs to the CinA family
SULPSESMR1_RS17040	COG1058	Belongs to the CinA family
SULPSESMR1_RS17060	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS17085	COG0446	pyridine nucleotide-disulphide oxidoreductase
SULPSESMR1_RS17085	COG1902	pentaerythritol trinitrate reductase activity
SULPSESMR1_RS17090	COG1051	belongs to the nudix hydrolase family
SULPSESMR1_RS17100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SULPSESMR1_RS17105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SULPSESMR1_RS17115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SULPSESMR1_RS17135	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
SULPSESMR1_RS17145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULPSESMR1_RS17145	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
SULPSESMR1_RS17155	COG0741	lytic transglycosylase activity
SULPSESMR1_RS17160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SULPSESMR1_RS17170	COG0437	4 iron, 4 sulfur cluster binding
SULPSESMR1_RS17175	COG0243	molybdopterin cofactor binding
SULPSESMR1_RS17180	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SULPSESMR1_RS17185	COG0028	Belongs to the TPP enzyme family
SULPSESMR1_RS17190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SULPSESMR1_RS17200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SULPSESMR1_RS17210	COG1116	anion transmembrane transporter activity
SULPSESMR1_RS17215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SULPSESMR1_RS17235	COG1802	Transcriptional regulator
SULPSESMR1_RS17245	COG0825	malonyl-CoA metabolic process
SULPSESMR1_RS17275	COG4948	Mandelate Racemase Muconate Lactonizing
SULPSESMR1_RS17300	COG0469	pyruvate kinase activity
SULPSESMR1_RS17310	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SULPSESMR1_RS17315	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SULPSESMR1_RS17325	COG1309	transcriptional regulator
SULPSESMR1_RS17330	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SULPSESMR1_RS17335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SULPSESMR1_RS17335	COG0072	phenylalanine-tRNA ligase activity
SULPSESMR1_RS17345	COG1970	mechanosensitive ion channel activity
SULPSESMR1_RS17350	COG0686	Belongs to the AlaDH PNT family
SULPSESMR1_RS17355	COG1522	sequence-specific DNA binding
SULPSESMR1_RS17370	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SULPSESMR1_RS17380	COG1063	alcohol dehydrogenase
SULPSESMR1_RS17445	COG1175	transmembrane transport
SULPSESMR1_RS17450	COG0395	ABC-type sugar transport system, permease component
SULPSESMR1_RS17455	COG3842	ATPase activity
SULPSESMR1_RS17480	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS17485	COG0179	Fumarylacetoacetate (FAA) hydrolase
SULPSESMR1_RS17490	COG4948	Mandelate Racemase Muconate Lactonizing
SULPSESMR1_RS17510	COG2197	response regulator
SULPSESMR1_RS17515	COG4585	Histidine kinase
SULPSESMR1_RS17520	COG1879	ABC-type sugar transport system periplasmic component
SULPSESMR1_RS17525	COG1129	ABC transporter
SULPSESMR1_RS17540	COG3386	PFAM SMP-30 Gluconolaconase
SULPSESMR1_RS17545	COG1285	pathogenesis
SULPSESMR1_RS17550	COG4993	Dehydrogenase
SULPSESMR1_RS17555	COG0531	amino acid
SULPSESMR1_RS17560	COG2010	Cytochrome c
SULPSESMR1_RS17560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SULPSESMR1_RS17610	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SULPSESMR1_RS17615	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS17620	COG0439	Biotin carboxylase
SULPSESMR1_RS17625	COG1309	transcriptional regulator
SULPSESMR1_RS17630	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS17635	COG3119	arylsulfatase activity
SULPSESMR1_RS17645	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS17660	COG1653	transport
SULPSESMR1_RS17675	COG3842	ATPase activity
SULPSESMR1_RS17700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SULPSESMR1_RS17710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS17715	COG0601	transmembrane transport
SULPSESMR1_RS17720	COG0747	negative chemotaxis
SULPSESMR1_RS17730	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS17760	COG2249	NAD(P)H dehydrogenase (quinone) activity
SULPSESMR1_RS17775	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS17790	COG0640	Transcriptional regulator
SULPSESMR1_RS17810	COG0640	Transcriptional regulator
SULPSESMR1_RS17825	COG3773	Cell wall hydrolase
SULPSESMR1_RS17835	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS17845	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS17850	COG0183	Belongs to the thiolase family
SULPSESMR1_RS17860	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS17875	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS17880	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS17895	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS17900	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS17905	COG2188	Transcriptional regulator
SULPSESMR1_RS17915	COG2826	transposase and inactivated derivatives, IS30 family
SULPSESMR1_RS17935	COG1192	Involved in chromosome partitioning
SULPSESMR1_RS17960	COG3852	Histidine kinase
SULPSESMR1_RS17975	COG3550	peptidyl-serine autophosphorylation
SULPSESMR1_RS17985	COG4372	Transposase
SULPSESMR1_RS18040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SULPSESMR1_RS18065	COG4608	Belongs to the ABC transporter superfamily
SULPSESMR1_RS18070	COG0444	Belongs to the ABC transporter superfamily
SULPSESMR1_RS18075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS18080	COG0601	transmembrane transport
SULPSESMR1_RS18130	COG2259	Doxx family
SULPSESMR1_RS18155	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS18160	COG2826	transposase and inactivated derivatives, IS30 family
SULPSESMR1_RS18175	COG2433	Pfam Transposase IS66
SULPSESMR1_RS18185	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS18195	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SULPSESMR1_RS18210	COG2132	Multicopper oxidase
SULPSESMR1_RS18235	COG0714	Associated with various cellular activities
SULPSESMR1_RS18245	COG2010	Cytochrome c
SULPSESMR1_RS18260	COG3794	PFAM blue (type 1) copper domain protein
SULPSESMR1_RS18270	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS18275	COG0154	amidase activity
SULPSESMR1_RS18280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS18285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SULPSESMR1_RS18300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SULPSESMR1_RS18310	COG1473	amidohydrolase
SULPSESMR1_RS18320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULPSESMR1_RS18335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS18350	COG4221	oxidoreductase activity
SULPSESMR1_RS18360	COG1522	sequence-specific DNA binding
SULPSESMR1_RS18395	COG5507	3-demethylubiquinone-9 3-methyltransferase
SULPSESMR1_RS18405	COG1120	ATPase activity
SULPSESMR1_RS18410	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SULPSESMR1_RS18415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SULPSESMR1_RS18430	COG4774	siderophore transport
SULPSESMR1_RS18435	COG1132	(ABC) transporter
SULPSESMR1_RS18485	COG0346	lactoylglutathione lyase activity
SULPSESMR1_RS18495	COG0523	cobalamin synthesis protein
SULPSESMR1_RS18510	COG4948	Mandelate Racemase Muconate Lactonizing
SULPSESMR1_RS18520	COG0747	negative chemotaxis
SULPSESMR1_RS18530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS18535	COG0444	Belongs to the ABC transporter superfamily
SULPSESMR1_RS18540	COG4608	Belongs to the ABC transporter superfamily
SULPSESMR1_RS18550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SULPSESMR1_RS18570	COG2205	protein histidine kinase activity
SULPSESMR1_RS18575	COG2204	response regulator
SULPSESMR1_RS18585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SULPSESMR1_RS18600	COG1126	abc transporter atp-binding protein
SULPSESMR1_RS18625	COG0765	amino acid transport
SULPSESMR1_RS18630	COG1126	abc transporter atp-binding protein
SULPSESMR1_RS18640	COG0747	negative chemotaxis
SULPSESMR1_RS18650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS18655	COG0444	Belongs to the ABC transporter superfamily
SULPSESMR1_RS18700	COG0489	protein tyrosine kinase activity
SULPSESMR1_RS18740	COG0437	4 iron, 4 sulfur cluster binding
SULPSESMR1_RS18745	COG2864	formate dehydrogenase
SULPSESMR1_RS18760	COG1609	Transcriptional regulator
SULPSESMR1_RS18770	COG0395	ABC-type sugar transport system, permease component
SULPSESMR1_RS18775	COG1175	transmembrane transport
SULPSESMR1_RS18780	COG3842	ATPase activity
SULPSESMR1_RS18790	COG0673	inositol 2-dehydrogenase activity
SULPSESMR1_RS18805	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS18810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SULPSESMR1_RS18830	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
SULPSESMR1_RS18840	COG2351	hydroxyisourate hydrolase activity
SULPSESMR1_RS18845	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS18865	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SULPSESMR1_RS18880	COG0402	S-adenosylhomocysteine deaminase activity
SULPSESMR1_RS18885	COG3257	ureidoglycine aminohydrolase activity
SULPSESMR1_RS18895	COG1414	Transcriptional regulator
SULPSESMR1_RS18900	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SULPSESMR1_RS18905	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SULPSESMR1_RS18910	COG3616	Alanine racemase, N-terminal domain
SULPSESMR1_RS18915	COG2423	ornithine cyclodeaminase activity
SULPSESMR1_RS18920	COG1414	Transcriptional regulator
SULPSESMR1_RS18930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SULPSESMR1_RS18935	COG0246	Mannitol dehydrogenase
SULPSESMR1_RS18940	COG1312	Catalyzes the dehydration of D-mannonate
SULPSESMR1_RS18945	COG1802	Transcriptional regulator
SULPSESMR1_RS18950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SULPSESMR1_RS18960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS18965	COG1063	alcohol dehydrogenase
SULPSESMR1_RS18970	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SULPSESMR1_RS18975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SULPSESMR1_RS18980	COG1780	Probably involved in ribonucleotide reductase function
SULPSESMR1_RS18985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SULPSESMR1_RS18990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SULPSESMR1_RS19005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SULPSESMR1_RS19020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SULPSESMR1_RS19030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SULPSESMR1_RS19035	COG4948	Mandelate Racemase Muconate Lactonizing
SULPSESMR1_RS19040	COG3618	amidohydrolase
SULPSESMR1_RS19045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SULPSESMR1_RS19055	COG3206	protein involved in exopolysaccharide biosynthesis
SULPSESMR1_RS19055	COG0489	protein tyrosine kinase activity
SULPSESMR1_RS19060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SULPSESMR1_RS19070	COG1086	Polysaccharide biosynthesis protein
SULPSESMR1_RS19075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SULPSESMR1_RS19095	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SULPSESMR1_RS19105	COG2089	acid synthase
SULPSESMR1_RS19160	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
SULPSESMR1_RS19170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SULPSESMR1_RS19180	COG1596	polysaccharide export
SULPSESMR1_RS19190	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SULPSESMR1_RS19205	COG0747	negative chemotaxis
SULPSESMR1_RS19220	COG0601	transmembrane transport
SULPSESMR1_RS19225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS19230	COG0584	glycerophosphoryl diester phosphodiesterase
SULPSESMR1_RS19245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SULPSESMR1_RS19250	COG1116	anion transmembrane transporter activity
SULPSESMR1_RS19260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SULPSESMR1_RS19265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SULPSESMR1_RS19275	COG2022	thiamine diphosphate biosynthetic process
SULPSESMR1_RS19290	COG0351	phosphomethylpyrimidine kinase
SULPSESMR1_RS19295	COG0693	protein deglycase activity
SULPSESMR1_RS19300	COG3852	Histidine kinase
SULPSESMR1_RS19320	COG3639	organic phosphonate transmembrane transporter activity
SULPSESMR1_RS19340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SULPSESMR1_RS19345	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SULPSESMR1_RS19350	COG1120	ATPase activity
SULPSESMR1_RS19355	COG4774	siderophore transport
SULPSESMR1_RS19365	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS19410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SULPSESMR1_RS19445	COG2226	methyltransferase
SULPSESMR1_RS19510	COG1132	(ABC) transporter
SULPSESMR1_RS19525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SULPSESMR1_RS19550	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS19555	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS19565	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS19585	COG0179	Fumarylacetoacetate (FAA) hydrolase
SULPSESMR1_RS19590	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SULPSESMR1_RS19610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS19615	COG0601	transmembrane transport
SULPSESMR1_RS19620	COG0747	negative chemotaxis
SULPSESMR1_RS19625	COG1802	Transcriptional regulator
SULPSESMR1_RS19635	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS19685	COG0174	glutamine synthetase
SULPSESMR1_RS19690	COG1012	belongs to the aldehyde dehydrogenase family
SULPSESMR1_RS19695	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS19700	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
SULPSESMR1_RS19715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SULPSESMR1_RS19720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SULPSESMR1_RS19730	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SULPSESMR1_RS19735	COG2218	PFAM glutamate synthase alpha subunit domain protein
SULPSESMR1_RS19740	COG0069	glutamate synthase activity
SULPSESMR1_RS19745	COG0174	glutamine synthetase
SULPSESMR1_RS19750	COG2826	transposase and inactivated derivatives, IS30 family
SULPSESMR1_RS19755	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS19765	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SULPSESMR1_RS19775	COG2721	sulfolactate sulfo-lyase activity
SULPSESMR1_RS19780	COG1802	Transcriptional regulator
SULPSESMR1_RS19785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SULPSESMR1_RS19790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SULPSESMR1_RS19815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SULPSESMR1_RS19825	COG2186	Transcriptional regulator
SULPSESMR1_RS19830	COG1691	(AIR) carboxylase
SULPSESMR1_RS19840	COG2186	Transcriptional regulator
SULPSESMR1_RS19850	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS19850	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
SULPSESMR1_RS19855	COG0028	Belongs to the TPP enzyme family
SULPSESMR1_RS19860	COG0277	FAD linked oxidase domain protein
SULPSESMR1_RS19865	COG0625	glutathione transferase activity
SULPSESMR1_RS19880	COG1454	alcohol dehydrogenase
SULPSESMR1_RS19885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SULPSESMR1_RS19900	COG0395	ABC-type sugar transport system, permease component
SULPSESMR1_RS19905	COG1175	transmembrane transport
SULPSESMR1_RS19915	COG3842	ATPase activity
SULPSESMR1_RS19925	COG1349	DNA-binding transcription factor activity
SULPSESMR1_RS19930	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS19935	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS19950	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS19955	COG5002	protein histidine kinase activity
SULPSESMR1_RS19960	COG5002	protein histidine kinase activity
SULPSESMR1_RS19965	COG4717	serine-type aminopeptidase activity
SULPSESMR1_RS19970	COG0420	3'-5' exonuclease activity
SULPSESMR1_RS19990	COG1414	Transcriptional regulator
SULPSESMR1_RS19995	COG0402	S-adenosylhomocysteine deaminase activity
SULPSESMR1_RS20005	COG2358	TRAP transporter, solute receptor (TAXI family
SULPSESMR1_RS20025	COG0446	pyridine nucleotide-disulphide oxidoreductase
SULPSESMR1_RS20025	COG1902	pentaerythritol trinitrate reductase activity
SULPSESMR1_RS20030	COG3938	Belongs to the proline racemase family
SULPSESMR1_RS20035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SULPSESMR1_RS20040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SULPSESMR1_RS20045	COG0569	domain protein
SULPSESMR1_RS20050	COG0798	PFAM Bile acid sodium symporter
SULPSESMR1_RS20065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SULPSESMR1_RS20095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SULPSESMR1_RS20100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SULPSESMR1_RS20120	COG0517	IMP dehydrogenase activity
SULPSESMR1_RS20125	COG4974	Belongs to the 'phage' integrase family
SULPSESMR1_RS20130	COG2205	protein histidine kinase activity
SULPSESMR1_RS20140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SULPSESMR1_RS20150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SULPSESMR1_RS20170	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
SULPSESMR1_RS20180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS20190	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SULPSESMR1_RS20195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SULPSESMR1_RS20215	COG0642	Histidine kinase
SULPSESMR1_RS20250	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SULPSESMR1_RS20250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SULPSESMR1_RS20325	COG1192	Involved in chromosome partitioning
SULPSESMR1_RS20365	COG3550	peptidyl-serine autophosphorylation
SULPSESMR1_RS20375	COG4974	Belongs to the 'phage' integrase family
SULPSESMR1_RS20405	COG0573	inorganic phosphate transmembrane transporter activity
SULPSESMR1_RS20410	COG0581	inorganic phosphate transmembrane transporter activity
SULPSESMR1_RS20415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SULPSESMR1_RS20420	COG0704	Plays a role in the regulation of phosphate uptake
SULPSESMR1_RS20425	COG0745	RESPONSE REGULATOR receiver
SULPSESMR1_RS20440	COG0701	Predicted permease
SULPSESMR1_RS20445	COG0640	Transcriptional regulator
SULPSESMR1_RS20450	COG0589	response to stress
SULPSESMR1_RS20455	COG0659	secondary active sulfate transmembrane transporter activity
SULPSESMR1_RS20460	COG4607	ABC-type enterochelin transport system periplasmic component
SULPSESMR1_RS20490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SULPSESMR1_RS20495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SULPSESMR1_RS20505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SULPSESMR1_RS20520	COG3395	kinase activity
SULPSESMR1_RS20525	COG1850	ribulose-bisphosphate carboxylase activity
SULPSESMR1_RS20535	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS20545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SULPSESMR1_RS20550	COG1609	Transcriptional regulator
SULPSESMR1_RS20575	COG0559	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS20580	COG4214	carbohydrate transport
SULPSESMR1_RS20585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SULPSESMR1_RS20590	COG0492	ferredoxin-NADP+ reductase activity
SULPSESMR1_RS20605	COG4964	Belongs to the GSP D family
SULPSESMR1_RS20690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SULPSESMR1_RS20715	COG2111	Na H antiporter
SULPSESMR1_RS20715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SULPSESMR1_RS20720	COG1006	Multisubunit Na H antiporter MnhC subunit
SULPSESMR1_RS20725	COG0651	ATP synthesis coupled electron transport
SULPSESMR1_RS20735	COG2212	antiporter activity
SULPSESMR1_RS20745	COG0671	phosphoesterase, PA-phosphatase related
SULPSESMR1_RS20825	COG0587	DNA-directed DNA polymerase activity
SULPSESMR1_RS20840	COG2183	response to ionizing radiation
SULPSESMR1_RS20850	COG1522	sequence-specific DNA binding
SULPSESMR1_RS20855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULPSESMR1_RS20860	COG0251	oxidation-reduction process
SULPSESMR1_RS20870	COG3048	D-serine ammonia-lyase activity
SULPSESMR1_RS20875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULPSESMR1_RS20890	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS20895	COG3180	Ammonia monooxygenase
SULPSESMR1_RS20910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS20915	COG0444	Belongs to the ABC transporter superfamily
SULPSESMR1_RS20920	COG4608	Belongs to the ABC transporter superfamily
SULPSESMR1_RS20940	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS20950	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS20990	COG0183	Belongs to the thiolase family
SULPSESMR1_RS20995	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS21015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SULPSESMR1_RS21025	COG4598	ABC transporter
SULPSESMR1_RS21030	COG0765	amino acid transport
SULPSESMR1_RS21035	COG0765	amino acid transport
SULPSESMR1_RS21055	COG3119	arylsulfatase activity
SULPSESMR1_RS21070	COG3938	Belongs to the proline racemase family
SULPSESMR1_RS21075	COG1902	pentaerythritol trinitrate reductase activity
SULPSESMR1_RS21075	COG0446	pyridine nucleotide-disulphide oxidoreductase
SULPSESMR1_RS21085	COG2207	Transcriptional regulator
SULPSESMR1_RS21090	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS21115	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS21120	COG1309	transcriptional regulator
SULPSESMR1_RS21125	COG2423	ornithine cyclodeaminase activity
SULPSESMR1_RS21130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULPSESMR1_RS21140	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS21145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SULPSESMR1_RS21150	COG0251	oxidation-reduction process
SULPSESMR1_RS21160	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS21170	COG0673	inositol 2-dehydrogenase activity
SULPSESMR1_RS21175	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS21190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SULPSESMR1_RS21220	COG0446	pyridine nucleotide-disulphide oxidoreductase
SULPSESMR1_RS21220	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SULPSESMR1_RS21250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
SULPSESMR1_RS21250	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS21255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SULPSESMR1_RS21260	COG1012	belongs to the aldehyde dehydrogenase family
SULPSESMR1_RS21275	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS21340	COG1802	Transcriptional regulator
SULPSESMR1_RS21345	COG0747	negative chemotaxis
SULPSESMR1_RS21350	COG0601	transmembrane transport
SULPSESMR1_RS21355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS21360	COG0444	Belongs to the ABC transporter superfamily
SULPSESMR1_RS21365	COG4608	Belongs to the ABC transporter superfamily
SULPSESMR1_RS21370	COG0405	Gamma-glutamyltransferase
SULPSESMR1_RS21385	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS21400	COG2826	transposase and inactivated derivatives, IS30 family
SULPSESMR1_RS21440	COG2198	Histidine kinase
SULPSESMR1_RS21440	COG2205	protein histidine kinase activity
SULPSESMR1_RS21440	COG0784	Response regulator, receiver
SULPSESMR1_RS21440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SULPSESMR1_RS21490	COG3451	type IV secretory pathway VirB4
SULPSESMR1_RS21515	COG3736	Type IV secretory pathway, component VirB8
SULPSESMR1_RS21520	COG3504	Conjugal transfer protein
SULPSESMR1_RS21525	COG2948	multi-organism process
SULPSESMR1_RS21530	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
SULPSESMR1_RS21565	COG1126	abc transporter atp-binding protein
SULPSESMR1_RS21580	COG3634	alkyl hydroperoxide reductase activity
SULPSESMR1_RS21590	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SULPSESMR1_RS21615	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS21620	COG2249	NAD(P)H dehydrogenase (quinone) activity
SULPSESMR1_RS21625	COG3246	L-lysine catabolic process to acetate
SULPSESMR1_RS21630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SULPSESMR1_RS21640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
SULPSESMR1_RS21650	COG3836	Belongs to the HpcH HpaI aldolase family
SULPSESMR1_RS21705	COG4423	Transcription factor
SULPSESMR1_RS21710	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
SULPSESMR1_RS21720	COG1349	DNA-binding transcription factor activity
SULPSESMR1_RS21740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULPSESMR1_RS21750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULPSESMR1_RS21755	COG0154	amidase activity
SULPSESMR1_RS21775	COG3181	Tripartite tricarboxylate transporter family receptor
SULPSESMR1_RS21810	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SULPSESMR1_RS21815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SULPSESMR1_RS21825	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SULPSESMR1_RS21830	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SULPSESMR1_RS21835	COG4974	Belongs to the 'phage' integrase family
SULPSESMR1_RS21870	COG1176	ABC-type spermidine putrescine transport system, permease component I
SULPSESMR1_RS21895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SULPSESMR1_RS21900	COG0235	Class ii aldolase
SULPSESMR1_RS21905	COG1070	Carbohydrate kinase
SULPSESMR1_RS21910	COG0028	Belongs to the TPP enzyme family
SULPSESMR1_RS21930	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS21935	COG0277	FAD linked oxidase domain protein
SULPSESMR1_RS21945	COG4604	ABC transporter, ATP-binding protein
SULPSESMR1_RS21950	COG4605	iron ion homeostasis
SULPSESMR1_RS21955	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SULPSESMR1_RS21960	COG4607	ABC-type enterochelin transport system periplasmic component
SULPSESMR1_RS21990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SULPSESMR1_RS21995	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
SULPSESMR1_RS22030	COG1959	2 iron, 2 sulfur cluster binding
SULPSESMR1_RS22040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SULPSESMR1_RS22050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SULPSESMR1_RS22065	COG1192	Involved in chromosome partitioning
SULPSESMR1_RS22070	COG1475	DNA binding
SULPSESMR1_RS22075	COG0640	Transcriptional regulator
SULPSESMR1_RS22120	COG2124	cytochrome p450
SULPSESMR1_RS22125	COG0633	Ferredoxin
SULPSESMR1_RS22135	COG1846	Transcriptional regulator
SULPSESMR1_RS22160	COG3415	Transposase
SULPSESMR1_RS22160	COG2801	Transposase and inactivated derivatives
SULPSESMR1_RS22165	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS22195	COG3845	ABC transporter
SULPSESMR1_RS22200	COG4603	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS22205	COG1079	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS22215	COG3311	Transcriptional regulator
SULPSESMR1_RS22235	COG2268	Band 7 protein
SULPSESMR1_RS22245	COG0559	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS22290	COG0420	3'-5' exonuclease activity
SULPSESMR1_RS22295	COG4717	serine-type aminopeptidase activity
SULPSESMR1_RS22335	COG1937	Protein conserved in bacteria
SULPSESMR1_RS22345	COG0303	'Molybdopterin
SULPSESMR1_RS22375	COG1733	regulation of RNA biosynthetic process
SULPSESMR1_RS22385	COG3384	dioxygenase
SULPSESMR1_RS22390	COG0702	epimerase
SULPSESMR1_RS22410	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS22425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SULPSESMR1_RS22440	COG1703	isobutyryl-CoA mutase activity
SULPSESMR1_RS22445	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULPSESMR1_RS22450	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULPSESMR1_RS22460	COG2226	methyltransferase
SULPSESMR1_RS22470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SULPSESMR1_RS22485	COG2030	dehydratase
SULPSESMR1_RS22510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SULPSESMR1_RS22540	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS22545	COG2030	dehydratase
SULPSESMR1_RS22550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SULPSESMR1_RS22550	COG1042	CoA-binding domain protein
SULPSESMR1_RS22550	COG0045	succinate-CoA ligase (ADP-forming) activity
SULPSESMR1_RS22555	COG0183	Belongs to the thiolase family
SULPSESMR1_RS22575	COG1309	transcriptional regulator
SULPSESMR1_RS22580	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS22585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULPSESMR1_RS22590	COG0702	epimerase
SULPSESMR1_RS22595	COG1902	pentaerythritol trinitrate reductase activity
SULPSESMR1_RS22595	COG0446	pyridine nucleotide-disulphide oxidoreductase
SULPSESMR1_RS22600	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS22615	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
SULPSESMR1_RS22620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SULPSESMR1_RS22635	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS22665	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
SULPSESMR1_RS22670	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS22675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SULPSESMR1_RS22690	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS22695	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS22700	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS22710	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
SULPSESMR1_RS22720	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS22725	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS22740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SULPSESMR1_RS22745	COG2030	dehydratase
SULPSESMR1_RS22750	COG0183	Belongs to the thiolase family
SULPSESMR1_RS22760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SULPSESMR1_RS22775	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS22780	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS22800	COG0559	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS22815	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS22825	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS22830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SULPSESMR1_RS22835	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS22845	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS22850	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS22855	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS22860	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS22865	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS22880	COG0183	Belongs to the thiolase family
SULPSESMR1_RS22940	COG1309	transcriptional regulator
SULPSESMR1_RS22960	COG0739	heme binding
SULPSESMR1_RS22960	COG0741	lytic transglycosylase activity
SULPSESMR1_RS22960	COG1196	nuclear chromosome segregation
SULPSESMR1_RS22985	COG0739	heme binding
SULPSESMR1_RS22985	COG1196	nuclear chromosome segregation
SULPSESMR1_RS22985	COG0741	lytic transglycosylase activity
SULPSESMR1_RS23005	COG2948	multi-organism process
SULPSESMR1_RS23030	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SULPSESMR1_RS23040	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SULPSESMR1_RS23045	COG3608	succinylglutamate desuccinylase aspartoacylase
SULPSESMR1_RS23045	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SULPSESMR1_RS23115	COG1012	belongs to the aldehyde dehydrogenase family
SULPSESMR1_RS23145	COG3077	Addiction module antitoxin, RelB DinJ family
SULPSESMR1_RS23165	COG3547	Transposase (IS116 IS110 IS902 family)
SULPSESMR1_RS23185	COG1414	Transcriptional regulator
SULPSESMR1_RS23195	COG1192	Involved in chromosome partitioning
SULPSESMR1_RS23215	COG0583	DNA-binding transcription factor activity
SULPSESMR1_RS23245	COG0492	ferredoxin-NADP+ reductase activity
SULPSESMR1_RS23260	COG0625	glutathione transferase activity
SULPSESMR1_RS23315	COG0625	glutathione transferase activity
SULPSESMR1_RS23325	COG0629	single-stranded DNA binding
SULPSESMR1_RS23345	COG1475	DNA binding
SULPSESMR1_RS23355	COG1475	DNA binding
SULPSESMR1_RS23360	COG1192	Involved in chromosome partitioning
SULPSESMR1_RS23375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SULPSESMR1_RS23400	COG2188	Transcriptional regulator
SULPSESMR1_RS23420	COG3627	carbon phosphorus lyase activity
SULPSESMR1_RS23425	COG4107	phosphonate C-P lyase system protein PhnK
SULPSESMR1_RS23430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SULPSESMR1_RS23435	COG3454	Phosphonate metabolism
SULPSESMR1_RS23450	COG3842	ATPase activity
SULPSESMR1_RS23455	COG1177	transmembrane transport
SULPSESMR1_RS23485	COG2801	Transposase and inactivated derivatives
SULPSESMR1_RS23530	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SULPSESMR1_RS23625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SULPSESMR1_RS23630	COG2226	methyltransferase
SULPSESMR1_RS23640	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SULPSESMR1_RS23675	COG1196	nuclear chromosome segregation
SULPSESMR1_RS23675	COG0739	heme binding
SULPSESMR1_RS23675	COG0741	lytic transglycosylase activity
SULPSESMR1_RS23695	COG0739	heme binding
SULPSESMR1_RS23695	COG1196	nuclear chromosome segregation
SULPSESMR1_RS23695	COG0741	lytic transglycosylase activity
SULPSESMR1_RS23730	COG4962	Type ii secretion system protein e
SULPSESMR1_RS23740	COG1487	ribonuclease activity
SULPSESMR1_RS23745	COG1002	Type II restriction enzyme, methylase subunits
SULPSESMR1_RS23760	COG1061	Type III restriction enzyme res subunit
SULPSESMR1_RS23765	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SULPSESMR1_RS23815	COG3831	ATPase activity
SULPSESMR1_RS23905	COG3609	addiction module antidote protein, CC2985 family
SULPSESMR1_RS23910	COG0629	single-stranded DNA binding
SULPSESMR1_RS23940	COG2169	Transcriptional regulator
SULPSESMR1_RS23940	COG1917	Cupin 2, conserved barrel domain protein
SULPSESMR1_RS23945	COG4106	trans-aconitate 2-methyltransferase activity
SULPSESMR1_RS23990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULPSESMR1_RS23995	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SULPSESMR1_RS24010	COG1414	Transcriptional regulator
SULPSESMR1_RS24015	COG1475	DNA binding
SULPSESMR1_RS24020	COG1192	Involved in chromosome partitioning
SULPSESMR1_RS24125	COG3938	Belongs to the proline racemase family
SULPSESMR1_RS24130	COG1902	pentaerythritol trinitrate reductase activity
SULPSESMR1_RS24130	COG0446	pyridine nucleotide-disulphide oxidoreductase
SULPSESMR1_RS24140	COG2423	ornithine cyclodeaminase activity
SULPSESMR1_RS24170	COG1475	DNA binding
SULPSESMR1_RS24175	COG2223	nitrite transmembrane transporter activity
SULPSESMR1_RS24200	COG0559	Belongs to the binding-protein-dependent transport system permease family
SULPSESMR1_RS24220	COG1396	sequence-specific DNA binding
SULPSESMR1_RS24235	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SULPSESMR1_RS24245	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SULPSESMR1_RS24255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SULPSESMR1_RS24260	COG1252	NADH dehydrogenase
SULPSESMR1_RS24285	COG0739	heme binding
SULPSESMR1_RS24285	COG0741	lytic transglycosylase activity
SULPSESMR1_RS24285	COG1196	nuclear chromosome segregation
SULPSESMR1_RS24300	COG3451	type IV secretory pathway VirB4
SULPSESMR1_RS24310	COG1196	nuclear chromosome segregation
SULPSESMR1_RS24310	COG0739	heme binding
SULPSESMR1_RS24310	COG0741	lytic transglycosylase activity
SULPSESMR1_RS24330	COG3736	Type IV secretory pathway, component VirB8
SULPSESMR1_RS24340	COG2948	multi-organism process
SULPSESMR1_RS24345	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
SULPSESMR1_RS24350	COG2176	DNA-directed DNA polymerase activity
SULPSESMR1_RS24350	COG5002	protein histidine kinase activity
SULPSESMR1_RS24390	COG3505	Type IV secretory pathway VirD4
SULPSESMR1_RS24395	COG3843	relaxase mobilization nuclease domain protein
SULPSESMR1_RS24470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULPSESMR1_RS24500	COG3505	Type IV secretory pathway VirD4
SULPSESMR1_RS24525	COG4962	Type ii secretion system protein e
SULPSESMR1_RS24530	COG2948	multi-organism process
SULPSESMR1_RS24550	COG0739	heme binding
SULPSESMR1_RS24550	COG1196	nuclear chromosome segregation
SULPSESMR1_RS24550	COG0741	lytic transglycosylase activity
SULPSESMR1_RS24570	COG1196	nuclear chromosome segregation
SULPSESMR1_RS24570	COG0741	lytic transglycosylase activity
SULPSESMR1_RS24570	COG0739	heme binding
SULPSESMR1_RS24605	COG1487	ribonuclease activity
SULPSESMR1_RS24610	COG1002	Type II restriction enzyme, methylase subunits
SULPSESMR1_RS24625	COG1061	Type III restriction enzyme res subunit
SULPSESMR1_RS24630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SULPSESMR1_RS24645	COG1022	Amp-dependent synthetase and ligase
SULPSESMR1_RS24670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
SULPSESMR1_RS24680	COG1960	acyl-CoA dehydrogenase activity
SULPSESMR1_RS24690	COG1024	Enoyl-CoA hydratase
SULPSESMR1_RS24695	COG1028	Short-chain dehydrogenase reductase Sdr
SULPSESMR1_RS24710	COG0318	PFAM AMP-dependent synthetase and ligase
SULPSESMR1_RS24740	COG2207	Transcriptional regulator
SULPSESMR1_RS24770	COG0420	3'-5' exonuclease activity
SULPSESMR1_RS24775	COG0419	ATPase involved in DNA repair
SULPSESMR1_RS24785	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SULPSESMR1_RS24800	COG1192	Involved in chromosome partitioning
SULPSESMR1_RS24810	COG0640	Transcriptional regulator