locus-tag	class	description
K3756_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K3756_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K3756_RS00050	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K3756_RS00055	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K3756_RS00085	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
K3756_RS00095	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
K3756_RS00105	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
K3756_RS00110	COG1999	signal sequence binding
K3756_RS00125	COG0802	atpase or kinase
K3756_RS00130	COG3178	'Phosphotransferase
K3756_RS00135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K3756_RS00140	COG2887	Belongs to the helicase family. UvrD subfamily
K3756_RS00160	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
K3756_RS00165	COG0667	Aldo Keto reductase
K3756_RS00170	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
K3756_RS00195	COG3030	protein affecting phage T7 exclusion by the F plasmid
K3756_RS00200	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
K3756_RS00205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K3756_RS00210	COG0237	dephospho-CoA kinase activity
K3756_RS00220	COG0424	maF-like protein
K3756_RS00225	COG1981	membrane
K3756_RS00230	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K3756_RS00235	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
K3756_RS00240	COG0445	tRNA wobble uridine modification
K3756_RS00245	COG0357	Ribosomal RNA small subunit methyltransferase G
K3756_RS00260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K3756_RS00265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K3756_RS00270	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K3756_RS00275	COG1420	regulation of RNA biosynthetic process
K3756_RS00280	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K3756_RS00285	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K3756_RS00295	COG0280	phosphate acetyltransferase
K3756_RS00295	COG0281	malic enzyme
K3756_RS00305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K3756_RS00315	COG0137	argininosuccinate synthase activity
K3756_RS00320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K3756_RS00325	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS00335	COG0745	RESPONSE REGULATOR receiver
K3756_RS00340	COG0494	nUDIX hydrolase
K3756_RS00345	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
K3756_RS00350	COG0494	nUDIX hydrolase
K3756_RS00355	COG0617	tRNA 3'-terminal CCA addition
K3756_RS00360	COG1132	(ABC) transporter
K3756_RS00365	COG1132	(ABC) transporter
K3756_RS00375	COG3034	peptidoglycan biosynthetic process
K3756_RS00400	COG2226	methyltransferase
K3756_RS00415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K3756_RS00425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K3756_RS00440	COG0779	Required for maturation of 30S ribosomal subunits
K3756_RS00455	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
K3756_RS00460	COG0494	nUDIX hydrolase
K3756_RS00465	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K3756_RS00470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K3756_RS00475	COG0653	protein targeting
K3756_RS00490	COG2003	Belongs to the UPF0758 family
K3756_RS00495	COG0484	heat shock protein binding
K3756_RS00500	COG0443	Heat shock 70 kDa protein
K3756_RS00520	COG1218	3'(2'),5'-bisphosphate nucleotidase
K3756_RS00525	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
K3756_RS00565	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K3756_RS00570	COG1137	ATPase activity
K3756_RS00590	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
K3756_RS00595	COG3327	negative regulation of DNA-templated transcription, initiation
K3756_RS00600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K3756_RS00610	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K3756_RS00615	COG2258	MOSC domain
K3756_RS00670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K3756_RS00680	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K3756_RS00690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K3756_RS00695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K3756_RS00705	COG0697	spore germination
K3756_RS00715	COG0776	regulation of translation
K3756_RS00720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K3756_RS00725	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
K3756_RS00750	COG1960	acyl-CoA dehydrogenase activity
K3756_RS00760	COG1024	Enoyl-CoA hydratase
K3756_RS00770	COG1596	polysaccharide export
K3756_RS00780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K3756_RS00785	COG1086	Polysaccharide biosynthesis protein
K3756_RS00790	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K3756_RS00820	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K3756_RS00825	COG0142	geranyltranstransferase activity
K3756_RS00830	COG1722	exodeoxyribonuclease VII activity
K3756_RS00835	COG0745	RESPONSE REGULATOR receiver
K3756_RS00840	COG1846	Transcriptional regulator
K3756_RS00845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K3756_RS00870	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K3756_RS00875	COG4143	(ABC) transporter
K3756_RS00885	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
K3756_RS00895	COG2808	Putative FMN-binding domain
K3756_RS00900	COG0625	glutathione transferase activity
K3756_RS00920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K3756_RS00925	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
K3756_RS00945	COG2838	Isocitrate dehydrogenase
K3756_RS00950	COG1653	transport
K3756_RS00955	COG1175	transmembrane transport
K3756_RS00960	COG0395	ABC-type sugar transport system, permease component
K3756_RS00965	COG3842	ATPase activity
K3756_RS00975	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
K3756_RS00980	COG1984	allophanate hydrolase subunit 2
K3756_RS00985	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K3756_RS01015	COG1414	Transcriptional regulator
K3756_RS01025	COG1609	Transcriptional regulator
K3756_RS01070	COG3093	addiction module antidote protein HigA
K3756_RS01080	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
K3756_RS01100	COG0732	type I restriction modification DNA specificity domain
K3756_RS01105	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
K3756_RS01135	COG4695	Portal protein
K3756_RS01170	COG1802	Transcriptional regulator
K3756_RS01170	COG4626	Terminase
K3756_RS01185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K3756_RS01190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K3756_RS01210	COG2010	Cytochrome c
K3756_RS01215	COG0348	domain, Protein
K3756_RS01240	COG0697	spore germination
K3756_RS01245	COG0473	3-isopropylmalate dehydrogenase activity
K3756_RS01260	COG0066	3-isopropylmalate dehydratase activity
K3756_RS01265	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K3756_RS01270	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
K3756_RS01270	COG3264	Mechanosensitive ion channel
K3756_RS01280	COG0799	negative regulation of ribosome biogenesis
K3756_RS01285	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
K3756_RS01310	COG0277	FAD linked oxidase domain protein
K3756_RS01315	COG0277	FAD linked oxidase domain protein
K3756_RS01325	COG0247	lactate metabolic process
K3756_RS01425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K3756_RS01445	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
K3756_RS01450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K3756_RS01460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K3756_RS01465	COG2116	formate transmembrane transporter activity
K3756_RS01470	COG1295	ribonuclease BN
K3756_RS01475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K3756_RS01495	COG0784	Response regulator, receiver
K3756_RS01525	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K3756_RS01535	COG0069	glutamate synthase activity
K3756_RS01570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K3756_RS01580	COG2995	paraquat-inducible protein a
K3756_RS01585	COG3008	intermembrane lipid transfer
K3756_RS01585	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K3756_RS01595	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K3756_RS01600	COG2897	thiosulfate sulfurtransferase activity
K3756_RS01610	COG0004	ammonium transporteR
K3756_RS01620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K3756_RS01625	COG0384	phenazine biosynthesis protein PhzF
K3756_RS01645	COG2154	pterin-4-alpha-carbinolamine dehydratase
K3756_RS01650	COG0668	transmembrane transport
K3756_RS01655	COG0678	peroxiredoxin activity
K3756_RS01665	COG0742	ribosomal rna small subunit methyltransferase
K3756_RS01675	COG0024	Methionine aminopeptidase
K3756_RS01680	COG1489	DNA binding
K3756_RS01685	COG1058	Belongs to the CinA family
K3756_RS01685	COG1546	Belongs to the CinA family
K3756_RS01710	COG0583	DNA-binding transcription factor activity
K3756_RS01715	COG2326	polyphosphate kinase activity
K3756_RS01725	COG0446	pyridine nucleotide-disulphide oxidoreductase
K3756_RS01725	COG1902	pentaerythritol trinitrate reductase activity
K3756_RS01735	COG1051	belongs to the nudix hydrolase family
K3756_RS01750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K3756_RS01755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K3756_RS01760	COG2169	Transcriptional regulator
K3756_RS01760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K3756_RS01765	COG2885	chlorophyll binding
K3756_RS01780	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
K3756_RS01795	COG0697	spore germination
K3756_RS01800	COG0741	lytic transglycosylase activity
K3756_RS01805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K3756_RS01820	COG0437	4 iron, 4 sulfur cluster binding
K3756_RS01825	COG0243	molybdopterin cofactor binding
K3756_RS01835	COG0028	Belongs to the TPP enzyme family
K3756_RS01840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K3756_RS01855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K3756_RS01885	COG0587	DNA-directed DNA polymerase activity
K3756_RS01905	COG1280	lysine exporter protein (LysE YggA)
K3756_RS01940	COG0825	malonyl-CoA metabolic process
K3756_RS01970	COG4948	Mandelate Racemase Muconate Lactonizing
K3756_RS01995	COG0469	pyruvate kinase activity
K3756_RS02005	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K3756_RS02010	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K3756_RS02020	COG1309	transcriptional regulator
K3756_RS02030	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K3756_RS02040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K3756_RS02040	COG0072	phenylalanine-tRNA ligase activity
K3756_RS02050	COG1280	lysine exporter protein (LysE YggA)
K3756_RS02055	COG0625	glutathione transferase activity
K3756_RS02060	COG1970	mechanosensitive ion channel activity
K3756_RS02075	COG0686	Belongs to the AlaDH PNT family
K3756_RS02080	COG1522	sequence-specific DNA binding
K3756_RS02095	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K3756_RS02105	COG1122	ATPase activity
K3756_RS02110	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K3756_RS02115	COG1268	BioY protein
K3756_RS02120	COG0183	Belongs to the thiolase family
K3756_RS02155	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K3756_RS02160	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
K3756_RS02165	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K3756_RS02175	COG2321	neutral zinc metallopeptidase
K3756_RS02190	COG2816	NAD+ diphosphatase activity
K3756_RS02205	COG3474	cytochrome
K3756_RS02210	COG4166	transmembrane transport
K3756_RS02215	COG4174	ABC transporter (Permease)
K3756_RS02220	COG4239	(ABC) transporter, permease
K3756_RS02225	COG4172	Belongs to the ABC transporter superfamily
K3756_RS02235	COG1686	Belongs to the peptidase S11 family
K3756_RS02245	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
K3756_RS02250	COG2813	Specifically methylates the guanine in position
K3756_RS02255	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS02260	COG0408	coproporphyrinogen oxidase activity
K3756_RS02300	COG2151	metal-sulfur cluster biosynthetic enzyme
K3756_RS02300	COG0489	protein tyrosine kinase activity
K3756_RS02320	COG0254	rRNA binding
K3756_RS02325	COG0335	large ribosomal subunit rRNA binding
K3756_RS02330	COG0336	Belongs to the RNA methyltransferase TrmD family
K3756_RS02345	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K3756_RS02355	COG0778	Nitroreductase
K3756_RS02360	COG0228	four-way junction DNA binding
K3756_RS02380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K3756_RS02385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K3756_RS02400	COG0640	Transcriptional regulator
K3756_RS02410	COG0356	it plays a direct role in the translocation of protons across the membrane
K3756_RS02415	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K3756_RS02420	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K3756_RS02425	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K3756_RS02465	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
K3756_RS02480	COG0435	Glutathione S-transferase
K3756_RS02490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K3756_RS02495	COG0242	peptide deformylase activity
K3756_RS02505	COG0242	peptide deformylase activity
K3756_RS02510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K3756_RS02520	COG2860	membrane
K3756_RS02525	COG0328	RNA-DNA hybrid ribonuclease activity
K3756_RS02540	COG1280	lysine exporter protein (LysE YggA)
K3756_RS02545	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K3756_RS02560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K3756_RS02565	COG1758	RNA polymerase activity
K3756_RS02570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K3756_RS02580	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
K3756_RS02585	COG0736	holo-[acyl-carrier-protein] synthase activity
K3756_RS02590	COG0681	Belongs to the peptidase S26 family
K3756_RS02595	COG0571	ribonuclease III activity
K3756_RS02600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K3756_RS02610	COG1381	Involved in DNA repair and RecF pathway recombination
K3756_RS02635	COG1396	sequence-specific DNA binding
K3756_RS02650	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
K3756_RS02655	COG0745	RESPONSE REGULATOR receiver
K3756_RS02660	COG2205	protein histidine kinase activity
K3756_RS02670	COG1660	Displays ATPase and GTPase activities
K3756_RS02690	COG1250	3-hydroxyacyl-CoA dehydrogenase
K3756_RS02720	COG0300	oxidoreductase activity
K3756_RS02730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K3756_RS02740	COG0501	Belongs to the peptidase M48B family
K3756_RS02755	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K3756_RS02765	COG0110	maltose O-acetyltransferase activity
K3756_RS02770	COG3685	Protein conserved in bacteria
K3756_RS02785	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K3756_RS02790	COG0250	Participates in transcription elongation, termination and antitermination
K3756_RS02800	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K3756_RS02805	COG0081	regulation of translation
K3756_RS02820	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K3756_RS02825	COG0222	ribosome binding
K3756_RS02830	COG0085	RNA polymerase activity
K3756_RS02835	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K3756_RS02855	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K3756_RS02860	COG0049	tRNA binding
K3756_RS02865	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K3756_RS02875	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K3756_RS02885	COG0051	transcription antitermination factor activity, RNA binding
K3756_RS02890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K3756_RS02895	COG0088	Forms part of the polypeptide exit tunnel
K3756_RS02900	COG0089	rRNA binding
K3756_RS02905	COG1278	Cold shock
K3756_RS02920	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K3756_RS02925	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
K3756_RS02930	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K3756_RS02935	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K3756_RS02940	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
K3756_RS02970	COG0255	Belongs to the universal ribosomal protein uL29 family
K3756_RS02975	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K3756_RS02980	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
K3756_RS02985	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K3756_RS02990	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K3756_RS02995	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K3756_RS03000	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K3756_RS03005	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K3756_RS03010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
K3756_RS03015	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
K3756_RS03020	COG1841	ribosomal large subunit assembly
K3756_RS03030	COG0200	Binds to the 23S rRNA
K3756_RS03035	COG0201	protein transport
K3756_RS03040	COG0563	adenylate kinase activity
K3756_RS03045	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K3756_RS03050	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K3756_RS03055	COG0202	RNA polymerase activity
K3756_RS03060	COG0203	ribosomal protein L17
K3756_RS03065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K3756_RS03070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K3756_RS03075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K3756_RS03080	COG0564	pseudouridine synthase activity
K3756_RS03085	COG0546	phosphoglycolate phosphatase activity
K3756_RS03095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K3756_RS03100	COG4597	amino acid ABC transporter
K3756_RS03105	COG0765	amino acid transport
K3756_RS03110	COG1126	abc transporter atp-binding protein
K3756_RS03125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K3756_RS03130	COG0218	Necessary for normal cell division and for the maintenance of normal septation
K3756_RS03140	COG0706	membrane insertase activity
K3756_RS03145	COG3300	MHYT domain
K3756_RS03145	COG5001	Diguanylate cyclase
K3756_RS03150	COG0037	tRNA processing
K3756_RS03160	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
K3756_RS03165	COG0594	ribonuclease P activity
K3756_RS03170	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K3756_RS03180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K3756_RS03185	COG3852	Histidine kinase
K3756_RS03200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K3756_RS03205	COG1414	Transcriptional regulator
K3756_RS03215	COG1116	anion transmembrane transporter activity
K3756_RS03220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K3756_RS03245	COG4176	ABC-type proline glycine betaine transport system permease component
K3756_RS03275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K3756_RS03285	COG0179	Fumarylacetoacetate (FAA) hydrolase
K3756_RS03295	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
K3756_RS03315	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
K3756_RS03325	COG1917	Cupin 2, conserved barrel domain protein
K3756_RS03330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K3756_RS03340	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K3756_RS03345	COG2847	Copper chaperone PCu(A)C
K3756_RS03355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K3756_RS03365	COG2205	protein histidine kinase activity
K3756_RS03370	COG1271	oxidase subunit
K3756_RS03375	COG1294	oxidase, subunit
K3756_RS03385	COG0604	alcohol dehydrogenase
K3756_RS03385	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS03385	COG3321	synthase
K3756_RS03395	COG1131	(ABC) transporter
K3756_RS03400	COG0842	Transport permease protein
K3756_RS03420	COG0322	excinuclease ABC activity
K3756_RS03425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K3756_RS03435	COG0314	molybdopterin synthase activity
K3756_RS03440	COG0589	response to stress
K3756_RS03460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K3756_RS03485	COG1510	regulation of RNA biosynthetic process
K3756_RS03495	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
K3756_RS03515	COG0540	Belongs to the ATCase OTCase family
K3756_RS03520	COG1573	uracil-dna glycosylase
K3756_RS03525	COG0521	Mo-molybdopterin cofactor biosynthetic process
K3756_RS03530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K3756_RS03545	COG1678	Uncharacterized ACR, COG1678
K3756_RS03550	COG0009	L-threonylcarbamoyladenylate synthase
K3756_RS03555	COG1960	acyl-CoA dehydrogenase activity
K3756_RS03590	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K3756_RS03595	COG0746	molybdenum cofactor guanylyltransferase activity
K3756_RS03600	COG1763	Mo-molybdopterin cofactor biosynthetic process
K3756_RS03605	COG0303	'Molybdopterin
K3756_RS03620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K3756_RS03630	COG0789	Transcriptional regulator
K3756_RS03650	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K3756_RS03655	COG0142	geranyltranstransferase activity
K3756_RS03680	COG0583	DNA-binding transcription factor activity
K3756_RS03695	COG5002	protein histidine kinase activity
K3756_RS03695	COG5001	Diguanylate cyclase
K3756_RS03700	COG2818	Glycosylase
K3756_RS03705	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K3756_RS03715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K3756_RS03720	COG0287	Prephenate dehydrogenase
K3756_RS03735	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
K3756_RS03760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K3756_RS03770	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K3756_RS03775	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
K3756_RS03780	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
K3756_RS03785	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K3756_RS03790	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K3756_RS03820	COG2983	Belongs to the UPF0260 family
K3756_RS03825	COG0196	riboflavin kinase activity
K3756_RS03830	COG2030	dehydratase
K3756_RS03840	COG1227	inorganic diphosphatase activity
K3756_RS03860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K3756_RS03865	COG0459	protein refolding
K3756_RS03875	COG2204	response regulator
K3756_RS03885	COG1056	cytidyltransferase-related domain
K3756_RS03885	COG1051	belongs to the nudix hydrolase family
K3756_RS03895	COG3454	Phosphonate metabolism
K3756_RS03900	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K3756_RS03915	COG0071	Belongs to the small heat shock protein (HSP20) family
K3756_RS03925	COG2046	Belongs to the sulfate adenylyltransferase family
K3756_RS03925	COG0529	Catalyzes the synthesis of activated sulfate
K3756_RS03930	COG0492	ferredoxin-NADP+ reductase activity
K3756_RS03935	COG1522	sequence-specific DNA binding
K3756_RS03950	COG1496	oxidoreductase activity
K3756_RS03960	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K3756_RS03980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K3756_RS03990	COG1435	thymidine kinase activity
K3756_RS04000	COG0431	NADPH-dependent FMN reductase
K3756_RS04020	COG0583	DNA-binding transcription factor activity
K3756_RS04040	COG3485	protocatechuate 3,4-dioxygenase
K3756_RS04060	COG4177	L-phenylalanine transmembrane transporter activity
K3756_RS04065	COG3246	L-lysine catabolic process to acetate
K3756_RS04070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K3756_RS04075	COG0596	Alpha beta hydrolase
K3756_RS04090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K3756_RS04095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K3756_RS04135	COG0281	malic enzyme
K3756_RS04135	COG0280	phosphate acetyltransferase
K3756_RS04145	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K3756_RS04150	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
K3756_RS04155	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K3756_RS04180	COG0318	PFAM AMP-dependent synthetase and ligase
K3756_RS04215	COG0183	Belongs to the thiolase family
K3756_RS04220	COG0625	glutathione transferase activity
K3756_RS04225	COG1960	acyl-CoA dehydrogenase activity
K3756_RS04235	COG1960	acyl-CoA dehydrogenase activity
K3756_RS04245	COG2197	response regulator
K3756_RS04270	COG0534	Mate efflux family protein
K3756_RS04275	COG1393	Belongs to the ArsC family
K3756_RS04300	COG0737	Belongs to the 5'-nucleotidase family
K3756_RS04305	COG2135	peptidase activity
K3756_RS04315	COG0583	DNA-binding transcription factor activity
K3756_RS04320	COG1960	acyl-CoA dehydrogenase activity
K3756_RS04330	COG3842	ATPase activity
K3756_RS04340	COG1175	transmembrane transport
K3756_RS04345	COG0395	ABC-type sugar transport system, permease component
K3756_RS04355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K3756_RS04385	COG1902	pentaerythritol trinitrate reductase activity
K3756_RS04400	COG0179	Fumarylacetoacetate (FAA) hydrolase
K3756_RS04405	COG4948	Mandelate Racemase Muconate Lactonizing
K3756_RS04425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K3756_RS04430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K3756_RS04455	COG1047	Peptidyl-prolyl cis-trans
K3756_RS04475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K3756_RS04480	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K3756_RS04490	COG0116	Belongs to the methyltransferase superfamily
K3756_RS04505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K3756_RS04520	COG1702	phosphate starvation-inducible protein PhoH
K3756_RS04525	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K3756_RS04530	COG1253	flavin adenine dinucleotide binding
K3756_RS04535	COG0815	Transfers the fatty acyl group on membrane lipoproteins
K3756_RS04540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K3756_RS04550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K3756_RS04560	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K3756_RS04570	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
K3756_RS04585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K3756_RS04590	COG0765	amino acid transport
K3756_RS04600	COG0539	negative regulation of cytoplasmic translation
K3756_RS04605	COG0776	regulation of translation
K3756_RS04615	COG0135	phosphoribosylanthranilate isomerase activity
K3756_RS04620	COG0133	tryptophan synthase activity
K3756_RS04635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K3756_RS04645	COG0193	aminoacyl-tRNA hydrolase activity
K3756_RS04660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K3756_RS04680	COG0159	tryptophan synthase activity
K3756_RS04690	COG0012	GTP binding
K3756_RS04710	COG2391	methyltransferase activity
K3756_RS04725	COG0785	Cytochrome C biogenesis protein
K3756_RS04750	COG3258	Cytochrome c
K3756_RS04755	COG0737	Belongs to the 5'-nucleotidase family
K3756_RS04770	COG3474	cytochrome
K3756_RS04775	COG0446	pyridine nucleotide-disulphide oxidoreductase
K3756_RS04785	COG0156	8-amino-7-oxononanoate synthase activity
K3756_RS04860	COG1175	transmembrane transport
K3756_RS04865	COG1653	transport
K3756_RS04875	COG0673	inositol 2-dehydrogenase activity
K3756_RS04885	COG1609	Transcriptional regulator
K3756_RS04895	COG3842	ATPase activity
K3756_RS04900	COG3842	ATPase activity
K3756_RS04910	COG0395	ABC-type sugar transport system, permease component
K3756_RS04915	COG1175	transmembrane transport
K3756_RS04925	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K3756_RS04930	COG1462	curli production assembly transport component CsgG
K3756_RS04975	COG0577	efflux transmembrane transporter activity
K3756_RS04980	COG1136	(ABC) transporter
K3756_RS04995	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K3756_RS05025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K3756_RS05050	COG0101	tRNA pseudouridine synthase activity
K3756_RS05055	COG3106	COG3106 Predicted ATPase
K3756_RS05065	COG3768	UPF0283 membrane protein
K3756_RS05080	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K3756_RS05085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K3756_RS05090	COG1183	phosphatidylcholine synthase activity
K3756_RS05105	COG0745	RESPONSE REGULATOR receiver
K3756_RS05110	COG4251	negative regulation of phosphorylation
K3756_RS05115	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K3756_RS05135	COG2264	protein methyltransferase activity
K3756_RS05155	COG0632	four-way junction helicase activity
K3756_RS05160	COG2255	four-way junction helicase activity
K3756_RS05170	COG0824	Thioesterase
K3756_RS05180	COG0848	biopolymer transport protein
K3756_RS05190	COG0823	Involved in the tonB-independent uptake of proteins
K3756_RS05195	COG2885	chlorophyll binding
K3756_RS05205	COG0037	tRNA processing
K3756_RS05210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K3756_RS05220	COG2759	Belongs to the formate--tetrahydrofolate ligase family
K3756_RS05230	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K3756_RS05245	COG1201	RNA secondary structure unwinding
K3756_RS05250	COG2084	Dehydrogenase
K3756_RS05300	COG4964	Belongs to the GSP D family
K3756_RS05325	COG0741	lytic transglycosylase activity
K3756_RS05335	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K3756_RS05350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K3756_RS05350	COG1754	DNA topoisomerase type I activity
K3756_RS05355	COG0758	DNA mediated transformation
K3756_RS05360	COG0312	modulator of DNA gyrase
K3756_RS05370	COG0109	protoheme IX farnesyltransferase activity
K3756_RS05380	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
K3756_RS05390	COG3346	SURF1 family
K3756_RS05425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K3756_RS05430	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
K3756_RS05440	COG0659	secondary active sulfate transmembrane transporter activity
K3756_RS05445	COG5002	protein histidine kinase activity
K3756_RS05450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K3756_RS05465	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
K3756_RS05470	COG4149	molybdate abc transporter
K3756_RS05475	COG0725	ABC transporter, periplasmic molybdate-binding protein
K3756_RS05500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K3756_RS05515	COG0583	DNA-binding transcription factor activity
K3756_RS05565	COG3657	addiction module killer protein
K3756_RS05640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K3756_RS05655	COG1492	cobalamin metabolic process
K3756_RS05670	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K3756_RS05675	COG0354	folic acid binding
K3756_RS05685	COG1132	(ABC) transporter
K3756_RS05690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K3756_RS05700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K3756_RS05720	COG0525	valine-tRNA ligase activity
K3756_RS05725	COG4251	negative regulation of phosphorylation
K3756_RS05745	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K3756_RS05750	COG0583	DNA-binding transcription factor activity
K3756_RS05755	COG2130	NADP-dependent
K3756_RS05760	COG0483	inositol monophosphate 1-phosphatase activity
K3756_RS05780	COG1522	sequence-specific DNA binding
K3756_RS05795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K3756_RS05805	COG0667	Aldo Keto reductase
K3756_RS05810	COG3246	L-lysine catabolic process to acetate
K3756_RS05820	COG1250	3-hydroxyacyl-CoA dehydrogenase
K3756_RS05820	COG0824	Thioesterase
K3756_RS05930	COG2977	Belongs to the P-Pant transferase superfamily
K3756_RS05950	COG0438	transferase activity, transferring glycosyl groups
K3756_RS05965	COG0489	protein tyrosine kinase activity
K3756_RS05965	COG3206	protein involved in exopolysaccharide biosynthesis
K3756_RS05980	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K3756_RS06035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K3756_RS06050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K3756_RS06060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K3756_RS06060	COG0446	pyridine nucleotide-disulphide oxidoreductase
K3756_RS06075	COG0358	DNA primase activity
K3756_RS06080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K3756_RS06085	COG0432	Pfam Uncharacterised protein family UPF0047
K3756_RS06105	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K3756_RS06110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K3756_RS06110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K3756_RS06135	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K3756_RS06135	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K3756_RS06140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
K3756_RS06145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K3756_RS06190	COG0564	pseudouridine synthase activity
K3756_RS06200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K3756_RS06225	COG1793	dna ligase
K3756_RS06260	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
K3756_RS06265	COG1329	Transcriptional regulator
K3756_RS06270	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
K3756_RS06275	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
K3756_RS06285	COG1522	sequence-specific DNA binding
K3756_RS06300	COG2873	o-acetylhomoserine
K3756_RS06325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K3756_RS06335	COG1832	CoA-binding protein
K3756_RS06340	COG0140	phosphoribosyl-ATP diphosphatase activity
K3756_RS06345	COG0107	imidazoleglycerol-phosphate synthase activity
K3756_RS06350	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K3756_RS06360	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K3756_RS06365	COG0131	Imidazoleglycerol-phosphate dehydratase
K3756_RS06380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K3756_RS06415	COG0438	transferase activity, transferring glycosyl groups
K3756_RS06420	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K3756_RS06430	COG1304	FMN binding
K3756_RS06435	COG0210	DNA helicase
K3756_RS06460	COG0489	protein tyrosine kinase activity
K3756_RS06470	COG2001	Belongs to the MraZ family
K3756_RS06475	COG0275	rRNA processing
K3756_RS06485	COG0768	penicillin binding
K3756_RS06490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K3756_RS06495	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K3756_RS06500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K3756_RS06505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K3756_RS06510	COG2081	HI0933 family
K3756_RS06525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K3756_RS06530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K3756_RS06555	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K3756_RS06560	COG1181	Belongs to the D-alanine--D-alanine ligase family
K3756_RS06565	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K3756_RS06570	COG0849	cell division
K3756_RS06575	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K3756_RS06580	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
K3756_RS06585	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K3756_RS06630	COG0484	heat shock protein binding
K3756_RS06660	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K3756_RS06690	COG0308	aminopeptidase N
K3756_RS06705	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K3756_RS06715	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K3756_RS06725	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS06740	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
K3756_RS06750	COG0534	Mate efflux family protein
K3756_RS06760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K3756_RS06765	COG0601	transmembrane transport
K3756_RS06775	COG4172	Belongs to the ABC transporter superfamily
K3756_RS06785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K3756_RS06790	COG1473	amidohydrolase
K3756_RS06795	COG1473	amidohydrolase
K3756_RS06800	COG0438	transferase activity, transferring glycosyl groups
K3756_RS06805	COG1519	Transferase
K3756_RS06810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K3756_RS06825	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K3756_RS06830	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K3756_RS06835	COG0546	phosphoglycolate phosphatase activity
K3756_RS06850	COG1960	acyl-CoA dehydrogenase activity
K3756_RS06860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K3756_RS06865	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K3756_RS06885	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K3756_RS06890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K3756_RS06895	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
K3756_RS06905	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K3756_RS06915	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K3756_RS06920	COG0649	NAD binding
K3756_RS06930	COG3743	rRNA binding
K3756_RS06930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K3756_RS06975	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K3756_RS06980	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K3756_RS06995	COG0713	ATP synthesis coupled electron transport
K3756_RS07010	COG1007	ATP synthesis coupled electron transport
K3756_RS07020	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
K3756_RS07030	COG0513	Belongs to the DEAD box helicase family
K3756_RS07040	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
K3756_RS07050	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS07055	COG4335	DNA alkylation repair
K3756_RS07060	COG3842	ATPase activity
K3756_RS07075	COG2378	regulation of single-species biofilm formation
K3756_RS07085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K3756_RS07090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K3756_RS07095	COG0805	protein transport
K3756_RS07105	COG0739	heme binding
K3756_RS07105	COG1388	LysM domain
K3756_RS07110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K3756_RS07115	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
K3756_RS07120	COG4221	oxidoreductase activity
K3756_RS07135	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K3756_RS07140	COG0642	Histidine kinase
K3756_RS07165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K3756_RS07180	COG0305	Participates in initiation and elongation during chromosome replication
K3756_RS07185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K3756_RS07190	COG0418	dihydroorotase activity
K3756_RS07225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K3756_RS07235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K3756_RS07260	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K3756_RS07265	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K3756_RS07270	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
K3756_RS07285	COG1138	Cytochrome C-type biogenesis protein
K3756_RS07290	COG3088	subunit of a heme lyase
K3756_RS07295	COG1024	Enoyl-CoA hydratase
K3756_RS07315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K3756_RS07320	COG0658	competence protein
K3756_RS07320	COG2333	competence protein COMEC
K3756_RS07325	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K3756_RS07330	COG0303	'Molybdopterin
K3756_RS07335	COG0315	cyclic pyranopterin monophosphate synthase activity
K3756_RS07340	COG0134	indole-3-glycerol-phosphate synthase activity
K3756_RS07345	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K3756_RS07350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K3756_RS07365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K3756_RS07375	COG0436	Aminotransferase
K3756_RS07380	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
K3756_RS07385	COG1280	lysine exporter protein (LysE YggA)
K3756_RS07395	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K3756_RS07400	COG0259	pyridoxamine-phosphate oxidase activity
K3756_RS07405	COG1278	Cold shock
K3756_RS07420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K3756_RS07450	COG0215	cysteine-tRNA ligase activity
K3756_RS07455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K3756_RS07470	COG2814	Major facilitator Superfamily
K3756_RS07510	COG0316	Belongs to the HesB IscA family
K3756_RS07515	COG0232	Belongs to the dGTPase family. Type 2 subfamily
K3756_RS07525	COG0018	arginyl-trna synthetase
K3756_RS07535	COG1472	Belongs to the glycosyl hydrolase 3 family
K3756_RS07540	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
K3756_RS07545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K3756_RS07555	COG0717	Belongs to the dCTP deaminase family
K3756_RS07570	COG0776	regulation of translation
K3756_RS07575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K3756_RS07580	COG0416	fatty acid biosynthetic process
K3756_RS07585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K3756_RS07605	COG0488	(ABC) transporter
K3756_RS07620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K3756_RS07625	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
K3756_RS07640	COG0148	phosphopyruvate hydratase activity
K3756_RS07645	COG0697	spore germination
K3756_RS07660	COG0513	Belongs to the DEAD box helicase family
K3756_RS07675	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
K3756_RS07690	COG3956	TIGRFAM MazG family protein
K3756_RS07695	COG1473	amidohydrolase
K3756_RS07700	COG0010	Belongs to the arginase family
K3756_RS07720	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K3756_RS07725	COG2890	protein-(glutamine-N5) methyltransferase activity
K3756_RS07735	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K3756_RS07740	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
K3756_RS07750	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
K3756_RS07765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K3756_RS07770	COG2927	DNA polymerase III (CHI subunit)
K3756_RS07780	COG3577	Aspartyl protease
K3756_RS07785	COG2095	MarC family integral membrane protein
K3756_RS07790	COG0488	(ABC) transporter
K3756_RS07795	COG0105	UTP biosynthetic process
K3756_RS07810	COG1858	cytochrome C peroxidase
K3756_RS07825	COG4213	ABC transporter substrate-binding protein
K3756_RS07830	COG4214	carbohydrate transport
K3756_RS07835	COG1129	ABC transporter
K3756_RS07840	COG1070	Carbohydrate kinase
K3756_RS07845	COG2115	Belongs to the xylose isomerase family
K3756_RS07855	COG2207	Transcriptional regulator
K3756_RS07865	COG0601	transmembrane transport
K3756_RS07870	COG4166	transmembrane transport
K3756_RS07900	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
K3756_RS07905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K3756_RS07910	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
K3756_RS07920	COG2166	iron-sulfur cluster assembly
K3756_RS07940	COG5012	cobalamin binding
K3756_RS07945	COG0646	methionine synthase
K3756_RS07945	COG1410	methionine synthase
K3756_RS07950	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K3756_RS07955	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K3756_RS07960	COG0047	phosphoribosylformylglycinamidine synthase activity
K3756_RS07970	COG2204	response regulator
K3756_RS07980	COG1530	ribonuclease E activity
K3756_RS07985	COG0425	Belongs to the sulfur carrier protein TusA family
K3756_RS07990	COG0785	Cytochrome C biogenesis protein
K3756_RS08005	COG3588	fructose-bisphosphate aldolase
K3756_RS08020	COG0114	fumarate hydratase activity
K3756_RS08030	COG2059	Chromate
K3756_RS08050	COG2186	Transcriptional regulator
K3756_RS08070	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K3756_RS08075	COG0604	alcohol dehydrogenase
K3756_RS08080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K3756_RS08085	COG0415	Belongs to the DNA photolyase family
K3756_RS08090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K3756_RS08100	COG0494	nUDIX hydrolase
K3756_RS08110	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
K3756_RS08110	COG3264	Mechanosensitive ion channel
K3756_RS08115	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K3756_RS08125	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
K3756_RS08125	COG1672	PFAM Archaeal ATPase
K3756_RS08145	COG0028	Belongs to the TPP enzyme family
K3756_RS08155	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K3756_RS08160	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K3756_RS08165	COG0297	glycogen (starch) synthase activity
K3756_RS08175	COG0033	Phosphoglucomutase
K3756_RS08180	COG0366	Alpha amylase catalytic
K3756_RS08215	COG3842	ATPase activity
K3756_RS08220	COG0366	Alpha amylase catalytic
K3756_RS08225	COG0395	ABC-type sugar transport system, permease component
K3756_RS08230	COG1175	transmembrane transport
K3756_RS08235	COG1653	transport
K3756_RS08240	COG1609	Transcriptional regulator
K3756_RS08260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K3756_RS08275	COG0346	lactoylglutathione lyase activity
K3756_RS08285	COG0433	COG0433 Predicted ATPase
K3756_RS08325	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
K3756_RS08335	COG1561	YicC-like family, N-terminal region
K3756_RS08340	COG0194	GDP metabolic process
K3756_RS08350	COG5002	protein histidine kinase activity
K3756_RS08360	COG0573	inorganic phosphate transmembrane transporter activity
K3756_RS08370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K3756_RS08380	COG0745	RESPONSE REGULATOR receiver
K3756_RS08385	COG0028	Belongs to the TPP enzyme family
K3756_RS08390	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K3756_RS08395	COG2771	luxR family
K3756_RS08400	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K3756_RS08405	COG0052	Belongs to the universal ribosomal protein uS2 family
K3756_RS08435	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K3756_RS08440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K3756_RS08445	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K3756_RS08460	COG0211	Belongs to the bacterial ribosomal protein bL27 family
K3756_RS08465	COG3743	rRNA binding
K3756_RS08465	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K3756_RS08485	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
K3756_RS08490	COG0248	Ppx GppA phosphatase
K3756_RS08500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K3756_RS08520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K3756_RS08535	COG0719	Fe-S assembly protein
K3756_RS08540	COG0396	ATPase activity
K3756_RS08550	COG0393	Putative heavy-metal-binding
K3756_RS08560	COG0719	Fe-S assembly protein
K3756_RS08575	COG2945	thiolester hydrolase activity
K3756_RS08590	COG0538	isocitrate dehydrogenase activity
K3756_RS08595	COG0668	transmembrane transport
K3756_RS08600	COG1217	gtp-binding protein TYPA
K3756_RS08610	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K3756_RS08615	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K3756_RS08640	COG0010	Belongs to the arginase family
K3756_RS08660	COG0166	Belongs to the GPI family
K3756_RS08670	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K3756_RS08675	COG5425	PFAM Usg family protein
K3756_RS08690	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K3756_RS08695	COG1612	heme a metabolic process
K3756_RS08705	COG0352	thiamine-phosphate diphosphorylase activity
K3756_RS08725	COG2313	pseudouridylate synthase activity
K3756_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS08745	COG4166	transmembrane transport
K3756_RS08780	COG2814	Major facilitator Superfamily
K3756_RS08785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K3756_RS08805	COG2084	Dehydrogenase
K3756_RS08810	COG2366	antibiotic biosynthetic process
K3756_RS08815	COG1187	pseudouridine synthase activity
K3756_RS08825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K3756_RS08830	COG1923	regulation of RNA biosynthetic process
K3756_RS08835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K3756_RS08840	COG0569	domain protein
K3756_RS08850	COG2204	response regulator
K3756_RS08855	COG5000	phosphorelay sensor kinase activity
K3756_RS08860	COG2204	response regulator
K3756_RS08865	COG3852	Histidine kinase
K3756_RS08870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K3756_RS08875	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
K3756_RS08875	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K3756_RS08880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K3756_RS08885	COG1058	Belongs to the CinA family
K3756_RS08885	COG1546	Belongs to the CinA family
K3756_RS08890	COG0004	ammonium transporteR
K3756_RS08900	COG2867	negative regulation of translational initiation
K3756_RS08905	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K3756_RS08915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K3756_RS08930	COG5598	trimethylamine methyltransferase
K3756_RS08935	COG0519	Catalyzes the synthesis of GMP from XMP
K3756_RS08935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K3756_RS08960	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
K3756_RS08965	COG2267	carboxylic ester hydrolase activity
K3756_RS08970	COG2326	polyphosphate kinase activity
K3756_RS08975	COG1309	transcriptional regulator
K3756_RS08990	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K3756_RS08995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K3756_RS09015	COG1858	cytochrome C peroxidase
K3756_RS09020	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
K3756_RS09025	COG2226	methyltransferase
K3756_RS09030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K3756_RS09035	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K3756_RS09050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K3756_RS09055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K3756_RS09060	COG0745	RESPONSE REGULATOR receiver
K3756_RS09070	COG0482	sulfurtransferase activity
K3756_RS09075	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K3756_RS09080	COG3494	Protein of unknown function (DUF1009)
K3756_RS09085	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K3756_RS09090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K3756_RS09100	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K3756_RS09110	COG0750	zinc metalloprotease
K3756_RS09115	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
K3756_RS09125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K3756_RS09130	COG0233	cytoplasmic translational termination
K3756_RS09135	COG0528	UMP kinase activity
K3756_RS09140	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K3756_RS09150	COG0601	transmembrane transport
K3756_RS09155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K3756_RS09170	COG0741	lytic transglycosylase activity
K3756_RS09175	COG0629	single-stranded DNA binding
K3756_RS09185	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K3756_RS09190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K3756_RS09205	COG4974	Belongs to the 'phage' integrase family
K3756_RS09210	COG4536	flavin adenine dinucleotide binding
K3756_RS09270	COG2814	Major facilitator Superfamily
K3756_RS09295	COG1238	metal cluster binding
K3756_RS09300	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
K3756_RS09310	COG0010	Belongs to the arginase family
K3756_RS09315	COG2423	ornithine cyclodeaminase activity
K3756_RS09330	COG0542	response to heat
K3756_RS09360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K3756_RS09390	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
K3756_RS09405	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
K3756_RS09425	COG0028	Belongs to the TPP enzyme family
K3756_RS09430	COG0440	acetolactate synthase activity
K3756_RS09450	COG4638	Rieske (2fe-2S)
K3756_RS09465	COG0154	amidase activity
K3756_RS09470	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
K3756_RS09475	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K3756_RS09480	COG0860	N-Acetylmuramoyl-L-alanine amidase
K3756_RS09485	COG0436	Aminotransferase
K3756_RS09490	COG0501	Belongs to the peptidase M48B family
K3756_RS09535	COG1335	isochorismatase
K3756_RS09545	COG0776	regulation of translation
K3756_RS09550	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K3756_RS09555	COG3396	Phenylacetate-CoA oxygenase
K3756_RS09560	COG3460	Phenylacetate-CoA oxygenase
K3756_RS09565	COG3396	Phenylacetate-CoA oxygenase
K3756_RS09570	COG2151	metal-sulfur cluster biosynthetic enzyme
K3756_RS09575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K3756_RS09585	COG1012	belongs to the aldehyde dehydrogenase family
K3756_RS09585	COG2030	dehydratase
K3756_RS09590	COG0343	queuine tRNA-ribosyltransferase activity
K3756_RS09605	COG2151	metal-sulfur cluster biosynthetic enzyme
K3756_RS09625	COG0149	triose-phosphate isomerase activity
K3756_RS09630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K3756_RS09635	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K3756_RS09640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K3756_RS09655	COG2124	cytochrome p450
K3756_RS09660	COG1522	sequence-specific DNA binding
K3756_RS09665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K3756_RS09665	COG1648	precorrin-2 dehydrogenase activity
K3756_RS09675	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K3756_RS09680	COG0175	sulfate reduction
K3756_RS09705	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K3756_RS09710	COG2885	chlorophyll binding
K3756_RS09735	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
K3756_RS09740	COG0271	Belongs to the BolA IbaG family
K3756_RS09745	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
K3756_RS09760	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K3756_RS09770	COG2354	Protein conserved in bacteria
K3756_RS09790	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K3756_RS09810	COG1960	acyl-CoA dehydrogenase activity
K3756_RS09815	COG1024	Enoyl-CoA hydratase
K3756_RS09825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K3756_RS09845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K3756_RS09855	COG2814	Major facilitator Superfamily
K3756_RS09860	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K3756_RS09870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K3756_RS09875	COG2833	Protein of unknown function (DUF455)
K3756_RS09880	COG0739	heme binding
K3756_RS09900	COG0126	phosphoglycerate kinase activity
K3756_RS09910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K3756_RS09915	COG0508	dehydrogenase complex catalyzes the overall conversion of
K3756_RS09915	COG0022	dehydrogenase e1 component
K3756_RS09920	COG0508	dehydrogenase complex catalyzes the overall conversion of
K3756_RS10005	COG4695	Portal protein
K3756_RS10020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K3756_RS10025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K3756_RS10040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K3756_RS10055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K3756_RS10060	COG3038	cytochrome b561
K3756_RS10065	COG2353	YceI-like domain
K3756_RS10075	COG0360	Binds together with S18 to 16S ribosomal RNA
K3756_RS10080	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
K3756_RS10085	COG0359	binds to the 23S rRNA
K3756_RS10095	COG0544	peptidyl-prolyl cis-trans isomerase activity
K3756_RS10100	COG3750	Belongs to the UPF0335 family
K3756_RS10145	COG0745	RESPONSE REGULATOR receiver
K3756_RS10150	COG3800	Transcriptional regulator
K3756_RS10150	COG1396	sequence-specific DNA binding
K3756_RS10160	COG0559	Belongs to the binding-protein-dependent transport system permease family
K3756_RS10175	COG0410	ABC transporter
K3756_RS10180	COG0511	ligase activity, forming carbon-carbon bonds
K3756_RS10185	COG0439	Biotin carboxylase
K3756_RS10190	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
K3756_RS10220	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K3756_RS10225	COG0740	serine-type endopeptidase activity
K3756_RS10260	COG1121	(ABC) transporter
K3756_RS10265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K3756_RS10275	COG3485	protocatechuate 3,4-dioxygenase
K3756_RS10280	COG3485	protocatechuate 3,4-dioxygenase
K3756_RS10285	COG0251	oxidation-reduction process
K3756_RS10305	COG1024	Enoyl-CoA hydratase
K3756_RS10310	COG1846	Transcriptional regulator
K3756_RS10420	COG0318	PFAM AMP-dependent synthetase and ligase
K3756_RS10425	COG1012	belongs to the aldehyde dehydrogenase family
K3756_RS10440	COG0747	negative chemotaxis
K3756_RS10445	COG4608	Belongs to the ABC transporter superfamily
K3756_RS10450	COG0444	Belongs to the ABC transporter superfamily
K3756_RS10455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K3756_RS10460	COG0601	transmembrane transport
K3756_RS10465	COG0747	negative chemotaxis
K3756_RS10475	COG0583	DNA-binding transcription factor activity
K3756_RS10480	COG4608	Belongs to the ABC transporter superfamily
K3756_RS10485	COG0444	Belongs to the ABC transporter superfamily
K3756_RS10490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K3756_RS10495	COG0601	transmembrane transport
K3756_RS10505	COG0747	negative chemotaxis
K3756_RS10520	COG0174	glutamine synthetase
K3756_RS10525	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
K3756_RS10570	COG1012	belongs to the aldehyde dehydrogenase family
K3756_RS10575	COG0318	PFAM AMP-dependent synthetase and ligase
K3756_RS10630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K3756_RS10640	COG2133	pyrroloquinoline quinone binding
K3756_RS10650	COG0488	(ABC) transporter
K3756_RS10655	COG0318	PFAM AMP-dependent synthetase and ligase
K3756_RS10675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K3756_RS10690	COG0583	DNA-binding transcription factor activity
K3756_RS10755	COG4249	Peptidase C14 caspase catalytic subunit p20
K3756_RS10755	COG2319	Wd-40 repeat
K3756_RS10765	COG3920	Histidine kinase
K3756_RS10765	COG2202	Pas domain
K3756_RS10770	COG2003	Belongs to the UPF0758 family
K3756_RS10790	COG0297	glycogen (starch) synthase activity
K3756_RS10805	COG0438	transferase activity, transferring glycosyl groups
K3756_RS10840	COG1840	ABC-type Fe3 transport system, periplasmic component
K3756_RS10850	COG0784	Response regulator, receiver
K3756_RS10850	COG4191	Histidine kinase
K3756_RS10875	COG2267	carboxylic ester hydrolase activity
K3756_RS10920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K3756_RS10920	COG1648	precorrin-2 dehydrogenase activity
K3756_RS10925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K3756_RS10930	COG0243	molybdopterin cofactor binding
K3756_RS10935	COG2146	nitrite reductase [NAD(P)H] activity
K3756_RS10940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K3756_RS10945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K3756_RS10945	COG1116	anion transmembrane transporter activity
K3756_RS10950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K3756_RS10955	COG1116	anion transmembrane transporter activity
K3756_RS10955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K3756_RS10960	COG1116	anion transmembrane transporter activity
K3756_RS10960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K3756_RS10965	COG3707	response regulator
K3756_RS10975	COG3920	Histidine kinase
K3756_RS10990	COG2202	Pas domain
K3756_RS10990	COG3920	Histidine kinase
K3756_RS11085	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K3756_RS11095	COG0019	diaminopimelate decarboxylase activity
K3756_RS11110	COG1285	pathogenesis
K3756_RS11145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K3756_RS11185	COG4251	negative regulation of phosphorylation
K3756_RS11190	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
K3756_RS11235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K3756_RS11240	COG0601	transmembrane transport
K3756_RS11255	COG0747	negative chemotaxis
K3756_RS11270	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
K3756_RS11315	COG0582	viral genome integration into host DNA
K3756_RS11330	COG1686	Belongs to the peptidase S11 family
K3756_RS11335	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K3756_RS11345	COG0084	hydrolase, TatD family'
K3756_RS11350	COG1234	tRNA 3'-trailer cleavage
K3756_RS11360	COG0544	peptidyl-prolyl cis-trans isomerase activity
K3756_RS11370	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K3756_RS11405	COG0006	proline dipeptidase activity
K3756_RS11425	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K3756_RS11460	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS11465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K3756_RS11475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K3756_RS11480	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K3756_RS11485	COG4133	protoheme IX ABC transporter activity
K3756_RS11490	COG3737	Protein of unknown function (DUF498/DUF598)
K3756_RS11500	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K3756_RS11505	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K3756_RS11510	COG1862	Preprotein translocase
K3756_RS11515	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K3756_RS11530	COG1160	GTP binding
K3756_RS11550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K3756_RS11565	COG5265	(ABC) transporter
K3756_RS11605	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K3756_RS11605	COG0446	pyridine nucleotide-disulphide oxidoreductase
K3756_RS11620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K3756_RS11630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K3756_RS11650	COG0730	response to heat
K3756_RS11655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K3756_RS11680	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
K3756_RS11685	COG0830	nickel cation binding
K3756_RS11690	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
K3756_RS11695	COG0804	urea catabolic process
K3756_RS11705	COG0832	Belongs to the urease beta subunit family
K3756_RS11710	COG0831	urea catabolic process
K3756_RS11715	COG0829	nickel cation binding
K3756_RS11730	COG0628	permease
K3756_RS11750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K3756_RS11760	COG0729	surface antigen
K3756_RS11765	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
K3756_RS11780	COG0321	lipoyl(octanoyl) transferase activity
K3756_RS11810	COG1610	YqeY-like protein
K3756_RS11815	COG0505	Belongs to the CarA family
K3756_RS11825	COG1802	Transcriptional regulator
K3756_RS11840	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K3756_RS11850	COG0156	8-amino-7-oxononanoate synthase activity
K3756_RS11855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K3756_RS11870	COG1522	sequence-specific DNA binding
K3756_RS11880	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K3756_RS11895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K3756_RS11900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K3756_RS11910	COG0574	Belongs to the PEP-utilizing enzyme family
K3756_RS11910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K3756_RS11915	COG0751	glycine-tRNA ligase activity
K3756_RS11935	COG0752	glycyl-tRNA synthetase alpha subunit
K3756_RS11950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K3756_RS11960	COG1469	GTP cyclohydrolase I activity
K3756_RS11975	COG0625	glutathione transferase activity
K3756_RS11990	COG0552	protein localization to endoplasmic reticulum
K3756_RS11995	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
K3756_RS12000	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K3756_RS12010	COG1570	exodeoxyribonuclease VII activity
K3756_RS12015	COG0151	Belongs to the GarS family
K3756_RS12040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K3756_RS12045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K3756_RS12050	COG0330	HflC and HflK could
K3756_RS12055	COG0330	HflC and HflK could
K3756_RS12065	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
K3756_RS12070	COG0625	glutathione transferase activity
K3756_RS12075	COG1760	l-serine dehydratase
K3756_RS12100	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K3756_RS12130	COG0504	CTP synthase activity
K3756_RS12135	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
K3756_RS12165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K3756_RS12170	COG4215	(ABC) transporter
K3756_RS12175	COG0765	amino acid transport
K3756_RS12180	COG0174	glutamine synthetase
K3756_RS12190	COG0174	glutamine synthetase
K3756_RS12195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K3756_RS12200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K3756_RS12215	COG3243	poly(R)-hydroxyalkanoic acid synthase
K3756_RS12255	COG0640	Transcriptional regulator
K3756_RS12275	COG2814	Major facilitator Superfamily
K3756_RS12280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K3756_RS12290	COG3220	belongs to the UPF0276 family
K3756_RS12305	COG1393	Belongs to the ArsC family
K3756_RS12310	COG1278	Cold shock
K3756_RS12320	COG1943	Transposase
K3756_RS12330	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
K3756_RS12370	COG1846	Transcriptional regulator
K3756_RS12395	COG0534	Mate efflux family protein
K3756_RS12405	COG0596	Alpha beta hydrolase
K3756_RS12415	COG0662	Cupin 2, conserved barrel domain protein
K3756_RS12420	COG0187	DNA topoisomerase II activity
K3756_RS12440	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
K3756_RS12445	COG1136	(ABC) transporter
K3756_RS12460	COG2133	pyrroloquinoline quinone binding
K3756_RS12465	COG0442	prolyl-tRNA aminoacylation
K3756_RS12500	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
K3756_RS12505	COG0457	Tetratricopeptide repeat
K3756_RS12510	COG0628	permease
K3756_RS12520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K3756_RS12540	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
K3756_RS12555	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K3756_RS12555	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K3756_RS12570	COG4770	biotin carboxylase activity
K3756_RS12600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K3756_RS12610	COG1396	sequence-specific DNA binding
K3756_RS12610	COG3800	Transcriptional regulator
K3756_RS12635	COG3119	arylsulfatase activity
K3756_RS12655	COG0217	transcriptional regulatory protein
K3756_RS12660	COG0490	domain, Protein
K3756_RS12660	COG0471	metal ion transport
K3756_RS12670	COG0471	metal ion transport
K3756_RS12670	COG3273	potassium ion transport
K3756_RS12675	COG1692	metallophosphoesterase
K3756_RS12680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K3756_RS12685	COG2239	Acts as a magnesium transporter
K3756_RS12690	COG0402	S-adenosylhomocysteine deaminase activity
K3756_RS12705	COG0483	inositol monophosphate 1-phosphatase activity
K3756_RS12710	COG1396	sequence-specific DNA binding
K3756_RS12720	COG0583	DNA-binding transcription factor activity
K3756_RS12725	COG0670	Belongs to the BI1 family
K3756_RS12735	COG3813	Protein conserved in bacteria
K3756_RS12740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K3756_RS12760	COG0154	amidase activity
K3756_RS12765	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K3756_RS12770	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K3756_RS12775	COG0590	tRNA wobble adenosine to inosine editing
K3756_RS12780	COG1187	pseudouridine synthase activity
K3756_RS12785	COG1253	flavin adenine dinucleotide binding
K3756_RS12795	COG3853	Toxic anion resistance protein (TelA)
K3756_RS12830	COG1490	D-aminoacyl-tRNA deacylase activity
K3756_RS12860	COG0747	negative chemotaxis
K3756_RS12870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K3756_RS12875	COG4172	Belongs to the ABC transporter superfamily
K3756_RS12880	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K3756_RS12885	COG0657	acetylesterase activity
K3756_RS12890	COG0318	PFAM AMP-dependent synthetase and ligase
K3756_RS12895	COG1652	LysM domain
K3756_RS12900	COG1132	(ABC) transporter
K3756_RS12915	COG0006	proline dipeptidase activity
K3756_RS12930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K3756_RS12930	COG2010	Cytochrome c
K3756_RS12950	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
K3756_RS12965	COG1320	monovalent cation:proton antiporter activity
K3756_RS12970	COG2212	antiporter activity
K3756_RS12980	COG0651	ATP synthesis coupled electron transport
K3756_RS12985	COG1006	Multisubunit Na H antiporter MnhC subunit
K3756_RS12990	COG2111	Na H antiporter
K3756_RS12990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K3756_RS13040	COG0395	ABC-type sugar transport system, permease component
K3756_RS13045	COG1175	transmembrane transport
K3756_RS13050	COG3842	ATPase activity
K3756_RS13070	COG1271	oxidase subunit
K3756_RS13075	COG1294	oxidase, subunit
K3756_RS13080	COG1181	Belongs to the D-alanine--D-alanine ligase family
K3756_RS13085	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K3756_RS13095	COG0306	phosphate transporter
K3756_RS13155	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
K3756_RS13160	COG1530	ribonuclease E activity
K3756_RS13165	COG0424	maF-like protein
K3756_RS13170	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K3756_RS13175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K3756_RS13185	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K3756_RS13195	COG0227	Belongs to the bacterial ribosomal protein bL28 family
K3756_RS13200	COG1703	isobutyryl-CoA mutase activity
K3756_RS13205	COG1643	Atp-dependent helicase
K3756_RS13225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K3756_RS13245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K3756_RS13260	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
K3756_RS13265	COG2943	transferase activity, transferring hexosyl groups
K3756_RS13280	COG1573	uracil-dna glycosylase
K3756_RS13300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K3756_RS13315	COG1272	protein, Hemolysin III
K3756_RS13350	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K3756_RS13360	COG0456	acetyltransferase
K3756_RS13365	COG1744	ABC transporter substrate-binding protein PnrA-like
K3756_RS13370	COG3845	ABC transporter
K3756_RS13375	COG4603	Belongs to the binding-protein-dependent transport system permease family
K3756_RS13380	COG1079	Belongs to the binding-protein-dependent transport system permease family
K3756_RS13385	COG0730	response to heat
K3756_RS13395	COG4221	oxidoreductase activity
K3756_RS13400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K3756_RS13420	COG0604	alcohol dehydrogenase
K3756_RS13425	COG2937	Belongs to the GPAT DAPAT family
K3756_RS13430	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K3756_RS13430	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K3756_RS13445	COG0813	purine-nucleoside phosphorylase activity
K3756_RS13500	COG0039	L-malate dehydrogenase activity
K3756_RS13520	COG2301	Belongs to the HpcH HpaI aldolase family
K3756_RS13535	COG2030	dehydratase
K3756_RS13545	COG0045	succinate-CoA ligase (ADP-forming) activity
K3756_RS13570	COG0567	Dehydrogenase, E1 component
K3756_RS13575	COG0508	dehydrogenase complex catalyzes the overall conversion of
K3756_RS13620	COG2884	Cell division ATP-binding protein ftsE
K3756_RS13635	COG0019	diaminopimelate decarboxylase activity
K3756_RS13650	COG0165	Argininosuccinate lyase
K3756_RS13655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K3756_RS13670	COG3119	arylsulfatase activity
K3756_RS13675	COG1741	Belongs to the pirin family
K3756_RS13680	COG0583	DNA-binding transcription factor activity
K3756_RS13685	COG0625	glutathione transferase activity
K3756_RS13690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K3756_RS13690	COG1017	nitric oxide dioxygenase activity
K3756_RS13715	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K3756_RS13730	COG4336	lyase activity
K3756_RS13735	COG0583	DNA-binding transcription factor activity
K3756_RS13750	COG0411	ABC transporter
K3756_RS13755	COG1172	Belongs to the binding-protein-dependent transport system permease family
K3756_RS13770	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K3756_RS13775	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
K3756_RS13780	COG2080	2 iron, 2 sulfur cluster binding
K3756_RS13785	COG1295	ribonuclease BN
K3756_RS13810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K3756_RS13815	COG3596	GTP binding
K3756_RS13855	COG0300	oxidoreductase activity
K3756_RS13860	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS13865	COG0583	DNA-binding transcription factor activity
K3756_RS13870	COG0318	PFAM AMP-dependent synthetase and ligase
K3756_RS13875	COG0583	DNA-binding transcription factor activity
K3756_RS13880	COG1063	alcohol dehydrogenase
K3756_RS13885	COG4319	ketosteroid isomerase
K3756_RS13900	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS13905	COG0583	DNA-binding transcription factor activity
K3756_RS13925	COG0667	Aldo Keto reductase
K3756_RS13930	COG0583	DNA-binding transcription factor activity
K3756_RS13935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K3756_RS13945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K3756_RS13950	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
K3756_RS13955	COG0124	histidyl-tRNA synthetase
K3756_RS13980	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K3756_RS13990	COG3845	ABC transporter
K3756_RS13995	COG4603	Belongs to the binding-protein-dependent transport system permease family
K3756_RS14000	COG1079	Belongs to the binding-protein-dependent transport system permease family
K3756_RS14010	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
K3756_RS14020	COG1917	Cupin 2, conserved barrel domain protein
K3756_RS14030	COG0667	Aldo Keto reductase
K3756_RS14060	COG0277	FAD linked oxidase domain protein
K3756_RS14065	COG0405	Gamma-glutamyltransferase
K3756_RS14080	COG1063	alcohol dehydrogenase
K3756_RS14115	COG1136	(ABC) transporter
K3756_RS14130	COG3254	rhamnose metabolic process
K3756_RS14135	COG1172	Belongs to the binding-protein-dependent transport system permease family
K3756_RS14140	COG1172	Belongs to the binding-protein-dependent transport system permease family
K3756_RS14145	COG1129	ABC transporter
K3756_RS14160	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS14160	COG3347	Dehydrogenase
K3756_RS14165	COG4952	isomerase
K3756_RS14170	COG2378	regulation of single-species biofilm formation
K3756_RS14195	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K3756_RS14220	COG1136	(ABC) transporter
K3756_RS14235	COG3243	poly(R)-hydroxyalkanoic acid synthase
K3756_RS14245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K3756_RS14250	COG0530	calcium, potassium:sodium antiporter activity
K3756_RS14265	COG0589	response to stress
K3756_RS14270	COG4191	Histidine kinase
K3756_RS14270	COG0784	Response regulator, receiver
K3756_RS14280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K3756_RS14315	COG0789	Transcriptional regulator
K3756_RS14355	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
K3756_RS14360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K3756_RS14370	COG0737	Belongs to the 5'-nucleotidase family
K3756_RS14380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K3756_RS14385	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
K3756_RS14425	COG2201	protein-glutamate methylesterase activity
K3756_RS14435	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
K3756_RS14440	COG3454	Phosphonate metabolism
K3756_RS14445	COG1129	ABC transporter
K3756_RS14450	COG4214	carbohydrate transport
K3756_RS14460	COG1609	Transcriptional regulator
K3756_RS14465	COG0673	inositol 2-dehydrogenase activity
K3756_RS14475	COG0673	inositol 2-dehydrogenase activity
K3756_RS14480	COG3962	Belongs to the TPP enzyme family
K3756_RS14485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K3756_RS14495	COG0191	fructose-bisphosphate aldolase activity
K3756_RS14500	COG0673	inositol 2-dehydrogenase activity
K3756_RS14510	COG3842	ATPase activity
K3756_RS14515	COG0395	ABC-type sugar transport system, permease component
K3756_RS14520	COG1175	transmembrane transport
K3756_RS14535	COG4989	oxidoreductase activity
K3756_RS14540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K3756_RS14545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K3756_RS14550	COG0673	inositol 2-dehydrogenase activity
K3756_RS14560	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K3756_RS14565	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
K3756_RS14570	COG0535	radical SAM domain protein
K3756_RS14575	COG0535	radical SAM domain protein
K3756_RS14580	COG0784	Response regulator, receiver
K3756_RS14580	COG2198	Histidine kinase
K3756_RS14580	COG2205	protein histidine kinase activity
K3756_RS14660	COG0366	Alpha amylase catalytic
K3756_RS14670	COG3842	ATPase activity
K3756_RS14675	COG0395	ABC-type sugar transport system, permease component
K3756_RS14680	COG1175	transmembrane transport
K3756_RS14705	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K3756_RS14705	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K3756_RS14715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
K3756_RS14720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K3756_RS14725	COG0129	dihydroxy-acid dehydratase activity
K3756_RS14730	COG0800	Aldolase
K3756_RS14735	COG3051	citrate lyase alpha subunit
K3756_RS14740	COG1840	ABC-type Fe3 transport system, periplasmic component
K3756_RS14775	COG0784	Response regulator, receiver
K3756_RS14775	COG2205	protein histidine kinase activity
K3756_RS14775	COG5002	protein histidine kinase activity
K3756_RS14795	COG0745	RESPONSE REGULATOR receiver
K3756_RS14805	COG0745	RESPONSE REGULATOR receiver
K3756_RS14810	COG5002	protein histidine kinase activity
K3756_RS14815	COG2205	protein histidine kinase activity
K3756_RS14815	COG3437	response regulator, receiver
K3756_RS14815	COG3850	Histidine kinase
K3756_RS14815	COG4999	Histidine kinase
K3756_RS14835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K3756_RS14855	COG0318	PFAM AMP-dependent synthetase and ligase
K3756_RS14860	COG1024	Enoyl-CoA hydratase
K3756_RS14870	COG1960	acyl-CoA dehydrogenase activity
K3756_RS14875	COG1960	acyl-CoA dehydrogenase activity
K3756_RS14880	COG0183	Belongs to the thiolase family
K3756_RS14885	COG1250	3-hydroxyacyl-CoA dehydrogenase
K3756_RS14885	COG1024	Enoyl-CoA hydratase
K3756_RS14925	COG0601	transmembrane transport
K3756_RS14930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K3756_RS14940	COG0668	transmembrane transport
K3756_RS14945	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
K3756_RS14960	COG0438	transferase activity, transferring glycosyl groups
K3756_RS14965	COG0588	phosphoglycerate mutase activity
K3756_RS14985	COG3246	L-lysine catabolic process to acetate
K3756_RS15005	COG0481	GTPase activity
K3756_RS15025	COG5328	Belongs to the UPF0262 family
K3756_RS15030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K3756_RS15040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K3756_RS15065	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
K3756_RS15070	COG3265	gluconokinase activity
K3756_RS15075	COG1609	Transcriptional regulator
K3756_RS15085	COG1573	uracil-dna glycosylase
K3756_RS15105	COG2951	lytic endotransglycosylase activity
K3756_RS15115	COG0154	amidase activity
K3756_RS15130	COG1177	transmembrane transport
K3756_RS15135	COG1176	ABC-type spermidine putrescine transport system, permease component I
K3756_RS15140	COG3842	ATPase activity
K3756_RS15145	COG2072	flavoprotein involved in K transport
K3756_RS15170	COG0076	glutamate decarboxylase activity
K3756_RS15175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K3756_RS15205	COG2197	response regulator
K3756_RS15210	COG0784	Response regulator, receiver
K3756_RS15210	COG2205	protein histidine kinase activity
K3756_RS15215	COG1366	Belongs to the anti-sigma-factor antagonist family
K3756_RS15235	COG1215	transferase activity, transferring glycosyl groups
K3756_RS15285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K3756_RS15290	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K3756_RS15290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K3756_RS15295	COG0509	glycine decarboxylation via glycine cleavage system
K3756_RS15300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K3756_RS15330	COG1228	amidohydrolase
K3756_RS15340	COG0601	transmembrane transport
K3756_RS15345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K3756_RS15355	COG4608	Belongs to the ABC transporter superfamily
K3756_RS15365	COG0556	nucleotide-excision repair
K3756_RS15390	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
K3756_RS15405	COG0697	spore germination
K3756_RS15410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K3756_RS15415	COG1115	amino acid carrier protein
K3756_RS15430	COG0488	(ABC) transporter
K3756_RS15440	COG0745	RESPONSE REGULATOR receiver
K3756_RS15450	COG1376	ErfK ybiS ycfS ynhG family protein
K3756_RS15465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K3756_RS15470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K3756_RS15475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K3756_RS15495	COG1309	transcriptional regulator
K3756_RS15510	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K3756_RS15515	COG0493	'glutamate synthase
K3756_RS15525	COG4181	ATPase activity
K3756_RS15540	COG0509	glycine decarboxylation via glycine cleavage system
K3756_RS15550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K3756_RS15600	COG3046	protein related to deoxyribodipyrimidine photolyase
K3756_RS15610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K3756_RS15635	COG0768	penicillin binding
K3756_RS15640	COG0772	Belongs to the SEDS family
K3756_RS15645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K3756_RS15650	COG0339	signal peptide processing
K3756_RS15655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K3756_RS15660	COG0756	dUTP diphosphatase activity
K3756_RS15665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K3756_RS15685	COG0406	alpha-ribazole phosphatase activity
K3756_RS15695	COG0606	chelatase, subunit chli
K3756_RS15710	COG0792	nuclease activity
K3756_RS15715	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K3756_RS15725	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
K3756_RS15750	COG0180	Tryptophanyl-tRNA synthetase
K3756_RS15755	COG2514	catechol 2,3-dioxygenase activity
K3756_RS15765	COG0778	Nitroreductase
K3756_RS15780	COG0346	lactoylglutathione lyase activity
K3756_RS15785	COG0745	RESPONSE REGULATOR receiver
K3756_RS15805	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K3756_RS15825	COG2132	Multicopper oxidase
K3756_RS15835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K3756_RS15860	COG0625	glutathione transferase activity
K3756_RS15905	COG1335	isochorismatase
K3756_RS15920	COG0174	glutamine synthetase
K3756_RS15925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K3756_RS15990	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
K3756_RS15995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K3756_RS16005	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
K3756_RS16020	COG0284	orotidine-5'-phosphate decarboxylase activity
K3756_RS16030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K3756_RS16045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K3756_RS16055	COG0625	glutathione transferase activity
K3756_RS16060	COG1178	ABC-type Fe3 transport system permease component
K3756_RS16065	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
K3756_RS16085	COG0559	Belongs to the binding-protein-dependent transport system permease family
K3756_RS16105	COG0745	RESPONSE REGULATOR receiver
K3756_RS16115	COG3383	formate dehydrogenase (NAD+) activity
K3756_RS16125	COG0625	glutathione transferase activity
K3756_RS16130	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS16150	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
K3756_RS16155	COG1595	DNA-templated transcription, initiation
K3756_RS16160	COG3806	Anti-sigma factor
K3756_RS16175	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K3756_RS16190	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
K3756_RS16195	COG3257	ureidoglycine aminohydrolase activity
K3756_RS16205	COG1652	LysM domain
K3756_RS16215	COG2351	hydroxyisourate hydrolase activity
K3756_RS16220	COG2205	protein histidine kinase activity
K3756_RS16225	COG0745	RESPONSE REGULATOR receiver
K3756_RS16240	COG1012	belongs to the aldehyde dehydrogenase family
K3756_RS16245	COG0612	Peptidase, M16
K3756_RS16250	COG0612	Peptidase, M16
K3756_RS16260	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K3756_RS16265	COG0138	bifunctional purine biosynthesis protein purh
K3756_RS16280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K3756_RS16280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K3756_RS16295	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
K3756_RS16300	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K3756_RS16310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K3756_RS16330	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K3756_RS16350	COG1185	polyribonucleotide nucleotidyltransferase activity
K3756_RS16360	COG0450	alkyl hydroperoxide reductase
K3756_RS16370	COG0564	pseudouridine synthase activity
K3756_RS16400	COG1280	lysine exporter protein (LysE YggA)
K3756_RS16405	COG1396	sequence-specific DNA binding
K3756_RS16430	COG1366	Belongs to the anti-sigma-factor antagonist family
K3756_RS16440	COG0405	Gamma-glutamyltransferase
K3756_RS16460	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K3756_RS16465	COG1674	ftsk spoiiie
K3756_RS16480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K3756_RS16485	COG2835	tetraacyldisaccharide 4'-kinase activity
K3756_RS16490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K3756_RS16505	COG0745	RESPONSE REGULATOR receiver
K3756_RS16520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K3756_RS16535	COG0495	leucyl-tRNA aminoacylation
K3756_RS16550	COG0625	glutathione transferase activity
K3756_RS16560	COG3264	Mechanosensitive ion channel
K3756_RS16560	COG1196	nuclear chromosome segregation
K3756_RS16570	COG1024	Enoyl-CoA hydratase
K3756_RS16585	COG0312	modulator of DNA gyrase
K3756_RS16600	COG1519	Transferase
K3756_RS16605	COG1663	tetraacyldisaccharide 4'-kinase activity
K3756_RS16615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K3756_RS16625	COG1194	a g-specific adenine glycosylase
K3756_RS16645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K3756_RS16670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K3756_RS16690	COG0288	reversible hydration of carbon dioxide
K3756_RS16700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K3756_RS16705	COG0791	NLP P60 protein
K3756_RS16715	COG2050	protein possibly involved in aromatic compounds catabolism
K3756_RS16735	COG0679	Auxin Efflux Carrier
K3756_RS16740	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
K3756_RS16745	COG1671	Belongs to the UPF0178 family
K3756_RS16755	COG2423	ornithine cyclodeaminase activity
K3756_RS16770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
K3756_RS16780	COG0285	dihydrofolate synthase activity
K3756_RS16785	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K3756_RS16800	COG0129	dihydroxy-acid dehydratase activity
K3756_RS16825	COG0793	Belongs to the peptidase S41A family
K3756_RS16835	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K3756_RS16850	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K3756_RS16850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K3756_RS16865	COG3622	Belongs to the hyi family
K3756_RS16875	COG0714	Associated with various cellular activities
K3756_RS16905	COG3022	response to hydroperoxide
K3756_RS16910	COG0514	ATP-dependent DNA helicase (RecQ)
K3756_RS16945	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
K3756_RS16965	COG1648	precorrin-2 dehydrogenase activity
K3756_RS16965	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K3756_RS16970	COG1797	cobyrinic acid a,c-diamide synthase activity
K3756_RS16975	COG2875	Belongs to the precorrin methyltransferase family
K3756_RS16990	COG2099	Precorrin-6x reductase
K3756_RS17045	COG0697	spore germination
K3756_RS17060	COG1121	(ABC) transporter
K3756_RS17065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K3756_RS17070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K3756_RS17075	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K3756_RS17085	COG1335	isochorismatase
K3756_RS17090	COG1054	Belongs to the UPF0176 family
K3756_RS17095	COG1360	Flagellar Motor Protein
K3756_RS17115	COG1706	bacterial-type flagellum-dependent cell motility
K3756_RS17120	COG1338	Plays a role in the flagellum-specific transport system
K3756_RS17125	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K3756_RS17135	COG1766	The M ring may be actively involved in energy transduction
K3756_RS17155	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K3756_RS17170	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K3756_RS17180	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K3756_RS17195	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
K3756_RS17205	COG4786	Flagellar basal body rod
K3756_RS17210	COG4786	Flagellar basal body rod
K3756_RS17215	COG1987	bacterial-type flagellum assembly
K3756_RS17220	COG1677	Flagellar hook-basal body complex protein FliE
K3756_RS17225	COG1558	bacterial-type flagellum-dependent cell motility
K3756_RS17245	COG5443	negative regulation of bacterial-type flagellum assembly
K3756_RS17255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K3756_RS17280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K3756_RS17285	COG1177	transmembrane transport
K3756_RS17290	COG1176	ABC-type spermidine putrescine transport system, permease component I
K3756_RS17295	COG3842	ATPase activity
K3756_RS17300	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
K3756_RS17310	COG3842	ATPase activity
K3756_RS17320	COG1176	ABC-type spermidine putrescine transport system, permease component I
K3756_RS17330	COG2951	lytic endotransglycosylase activity
K3756_RS17345	COG0557	exoribonuclease II activity
K3756_RS17355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K3756_RS17370	COG0346	lactoylglutathione lyase activity
K3756_RS17390	COG2171	N-acyltransferase activity
K3756_RS17410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K3756_RS17415	COG0569	domain protein
K3756_RS17420	COG0820	rRNA (adenine-C2-)-methyltransferase activity
K3756_RS17440	COG0560	Phosphoserine phosphatase
K3756_RS17445	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
K3756_RS17450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K3756_RS17470	COG1063	alcohol dehydrogenase
K3756_RS17475	COG0156	8-amino-7-oxononanoate synthase activity
K3756_RS17480	COG1396	sequence-specific DNA binding
K3756_RS17485	COG0183	Belongs to the thiolase family
K3756_RS17495	COG2226	methyltransferase
K3756_RS17500	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K3756_RS17505	COG1024	Enoyl-CoA hydratase
K3756_RS17510	COG0268	Binds directly to 16S ribosomal RNA
K3756_RS17585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K3756_RS17590	COG3483	tryptophan 2,3-dioxygenase activity
K3756_RS17605	COG3474	cytochrome
K3756_RS17610	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
K3756_RS17615	COG2211	Major facilitator Superfamily
K3756_RS17620	COG0644	oxidoreductase
K3756_RS17625	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
K3756_RS17630	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K3756_RS17665	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
K3756_RS17670	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
K3756_RS17680	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
K3756_RS17685	COG1063	alcohol dehydrogenase
K3756_RS17690	COG0500	methyltransferase
K3756_RS17695	COG0142	geranyltranstransferase activity
K3756_RS17700	COG1233	COG1233 Phytoene dehydrogenase and related
K3756_RS17705	COG5621	secreted hydrolase
K3756_RS17710	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
K3756_RS17715	COG1562	ergosterol biosynthetic process
K3756_RS17720	COG1233	COG1233 Phytoene dehydrogenase and related
K3756_RS17730	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
K3756_RS17735	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
K3756_RS17750	COG1192	Involved in chromosome partitioning
K3756_RS17760	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K3756_RS17765	COG0181	hydroxymethylbilane synthase activity
K3756_RS17770	COG0156	8-amino-7-oxononanoate synthase activity
K3756_RS17780	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
K3756_RS17815	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
K3756_RS17820	COG1429	ligase activity, forming nitrogen-metal bonds
K3756_RS17825	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
K3756_RS17830	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
K3756_RS17880	COG1846	Transcriptional regulator
K3756_RS17920	COG3708	Transcriptional regulator
K3756_RS17920	COG2207	Transcriptional regulator
K3756_RS17925	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
K3756_RS17960	COG2188	Transcriptional regulator
K3756_RS17965	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K3756_RS17975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K3756_RS18030	COG0277	FAD linked oxidase domain protein
K3756_RS18035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K3756_RS18050	COG1053	succinate dehydrogenase
K3756_RS18060	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
K3756_RS18065	COG0583	DNA-binding transcription factor activity
K3756_RS18085	COG4692	amylo-alpha-1,6-glucosidase activity
K3756_RS18095	COG1960	acyl-CoA dehydrogenase activity
K3756_RS18100	COG1946	Acyl-CoA thioesterase
K3756_RS18155	COG1960	acyl-CoA dehydrogenase activity
K3756_RS18160	COG1960	acyl-CoA dehydrogenase activity
K3756_RS18165	COG0604	alcohol dehydrogenase
K3756_RS18165	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS18165	COG3321	synthase
K3756_RS18190	COG3852	Histidine kinase
K3756_RS18195	COG2204	response regulator
K3756_RS18215	COG0437	4 iron, 4 sulfur cluster binding
K3756_RS18285	COG1088	dTDP-glucose 4,6-dehydratase activity
K3756_RS18315	COG1215	transferase activity, transferring glycosyl groups
K3756_RS18350	COG1192	Involved in chromosome partitioning
K3756_RS18370	COG0662	Cupin 2, conserved barrel domain protein
K3756_RS18370	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
K3756_RS18385	COG2813	Specifically methylates the guanine in position
K3756_RS18395	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
K3756_RS18420	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
K3756_RS18450	COG3386	PFAM SMP-30 Gluconolaconase
K3756_RS18475	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS18490	COG0395	ABC-type sugar transport system, permease component
K3756_RS18495	COG1175	transmembrane transport
K3756_RS18520	COG1192	Involved in chromosome partitioning
K3756_RS18535	COG1802	Transcriptional regulator
K3756_RS18545	COG0444	Belongs to the ABC transporter superfamily
K3756_RS18550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K3756_RS18560	COG4533	DNA binding
K3756_RS18570	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
K3756_RS18595	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K3756_RS18630	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS18650	COG3386	PFAM SMP-30 Gluconolaconase
K3756_RS18655	COG0800	Aldolase
K3756_RS18660	COG3734	2-keto-3-deoxy-galactonokinase
K3756_RS18665	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS18670	COG0129	dihydroxy-acid dehydratase activity
K3756_RS18680	COG0395	ABC-type sugar transport system, permease component
K3756_RS18685	COG1175	transmembrane transport
K3756_RS18710	COG1192	Involved in chromosome partitioning
K3756_RS18740	COG0444	Belongs to the ABC transporter superfamily
K3756_RS18745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K3756_RS18775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K3756_RS18785	COG3668	Plasmid stabilization system
K3756_RS18790	COG3609	addiction module antidote protein, CC2985 family
K3756_RS18810	COG1192	Involved in chromosome partitioning
K3756_RS18855	COG1028	Short-chain dehydrogenase reductase Sdr
K3756_RS18860	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K3756_RS18870	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K3756_RS18895	COG1309	transcriptional regulator
K3756_RS18910	COG0577	efflux transmembrane transporter activity
K3756_RS18910	COG1136	(ABC) transporter
K3756_RS18945	COG2814	Major facilitator Superfamily
K3756_RS18970	COG1228	amidohydrolase
K3756_RS18980	COG2207	Transcriptional regulator
K3756_RS19000	COG1574	metal-dependent hydrolase with the TIM-barrel fold
K3756_RS19005	COG2814	Major facilitator Superfamily
K3756_RS19030	COG0346	lactoylglutathione lyase activity
K3756_RS19050	COG2207	Transcriptional regulator
K3756_RS19075	COG0519	Catalyzes the synthesis of GMP from XMP
K3756_RS19155	COG1104	cysteine desulfurase activity
K3756_RS19240	COG3505	Type IV secretory pathway VirD4
K3756_RS19275	COG1230	cation diffusion facilitator family transporter
K3756_RS19280	COG0789	Transcriptional regulator
K3756_RS19320	COG2132	Multicopper oxidase
K3756_RS19330	COG1937	Protein conserved in bacteria
K3756_RS19365	COG4962	Type ii secretion system protein e
K3756_RS19370	COG2948	multi-organism process
K3756_RS19390	COG1196	nuclear chromosome segregation
K3756_RS19390	COG0741	lytic transglycosylase activity
K3756_RS19390	COG0739	heme binding
K3756_RS19410	COG0739	heme binding
K3756_RS19410	COG0741	lytic transglycosylase activity
K3756_RS19410	COG1196	nuclear chromosome segregation
K3756_RS19430	COG1733	regulation of RNA biosynthetic process
K3756_RS19435	COG0604	alcohol dehydrogenase
K3756_RS19445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K3756_RS19470	COG1012	belongs to the aldehyde dehydrogenase family
K3756_RS19475	COG1959	2 iron, 2 sulfur cluster binding
K3756_RS19530	COG3842	ATPase activity
K3756_RS19535	COG1192	Involved in chromosome partitioning
K3756_RS19545	COG1414	Transcriptional regulator