locus-tag	class	description
C1J03_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C1J03_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C1J03_RS00145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C1J03_RS00150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C1J03_RS00155	COG2350	Protein conserved in bacteria
C1J03_RS00175	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1J03_RS00190	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C1J03_RS00200	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C1J03_RS00260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1J03_RS00270	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
C1J03_RS00275	COG1999	signal sequence binding
C1J03_RS00290	COG0802	atpase or kinase
C1J03_RS00295	COG3178	'Phosphotransferase
C1J03_RS00300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C1J03_RS00305	COG2887	Belongs to the helicase family. UvrD subfamily
C1J03_RS00310	COG1074	ATP-dependent DNA helicase activity
C1J03_RS00325	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C1J03_RS00330	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C1J03_RS00355	COG3030	protein affecting phage T7 exclusion by the F plasmid
C1J03_RS00360	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C1J03_RS00365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C1J03_RS00370	COG0237	dephospho-CoA kinase activity
C1J03_RS00375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C1J03_RS00380	COG0424	maF-like protein
C1J03_RS00390	COG1981	membrane
C1J03_RS00395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C1J03_RS00400	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C1J03_RS00405	COG0445	tRNA wobble uridine modification
C1J03_RS00410	COG0357	Ribosomal RNA small subunit methyltransferase G
C1J03_RS00425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1J03_RS00430	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C1J03_RS00435	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C1J03_RS00440	COG1420	regulation of RNA biosynthetic process
C1J03_RS00445	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C1J03_RS00450	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C1J03_RS00455	COG0281	malic enzyme
C1J03_RS00455	COG0280	phosphate acetyltransferase
C1J03_RS00460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1J03_RS00465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1J03_RS00470	COG0137	argininosuccinate synthase activity
C1J03_RS00475	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C1J03_RS00480	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS00505	COG0494	nUDIX hydrolase
C1J03_RS00510	COG0617	tRNA 3'-terminal CCA addition
C1J03_RS00515	COG1132	(ABC) transporter
C1J03_RS00520	COG1132	(ABC) transporter
C1J03_RS00525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1J03_RS00530	COG3034	peptidoglycan biosynthetic process
C1J03_RS00555	COG2226	methyltransferase
C1J03_RS00570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1J03_RS00580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1J03_RS00590	COG0747	negative chemotaxis
C1J03_RS00595	COG0779	Required for maturation of 30S ribosomal subunits
C1J03_RS00610	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C1J03_RS00615	COG0494	nUDIX hydrolase
C1J03_RS00620	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C1J03_RS00625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1J03_RS00630	COG0653	protein targeting
C1J03_RS00645	COG0484	heat shock protein binding
C1J03_RS00650	COG0443	Heat shock 70 kDa protein
C1J03_RS00665	COG1218	3'(2'),5'-bisphosphate nucleotidase
C1J03_RS00670	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C1J03_RS00685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1J03_RS00710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1J03_RS00715	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C1J03_RS00720	COG1137	ATPase activity
C1J03_RS00725	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C1J03_RS00735	COG0517	IMP dehydrogenase activity
C1J03_RS00735	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C1J03_RS00745	COG3327	negative regulation of DNA-templated transcription, initiation
C1J03_RS00750	COG0668	transmembrane transport
C1J03_RS00780	COG0800	Aldolase
C1J03_RS00785	COG3734	2-keto-3-deoxy-galactonokinase
C1J03_RS00790	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS00795	COG0129	dihydroxy-acid dehydratase activity
C1J03_RS00810	COG1175	transmembrane transport
C1J03_RS00820	COG1414	Transcriptional regulator
C1J03_RS00865	COG2390	Transcriptional regulator
C1J03_RS00870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1J03_RS00900	COG2828	Protein conserved in bacteria
C1J03_RS00910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1J03_RS00915	COG3180	Ammonia monooxygenase
C1J03_RS00920	COG1802	Transcriptional regulator
C1J03_RS00925	COG1053	succinate dehydrogenase
C1J03_RS00980	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C1J03_RS00985	COG3119	arylsulfatase activity
C1J03_RS00995	COG0714	Associated with various cellular activities
C1J03_RS01015	COG2304	oxidoreductase activity
C1J03_RS01040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1J03_RS01050	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1J03_RS01055	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C1J03_RS01060	COG3064	Membrane
C1J03_RS01075	COG0583	DNA-binding transcription factor activity
C1J03_RS01090	COG1228	amidohydrolase
C1J03_RS01095	COG2986	histidine ammonia-lyase
C1J03_RS01105	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C1J03_RS01110	COG2020	methyltransferase activity
C1J03_RS01115	COG1473	amidohydrolase
C1J03_RS01120	COG0181	hydroxymethylbilane synthase activity
C1J03_RS01125	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C1J03_RS01130	COG2723	6-phospho-beta-galactosidase activity
C1J03_RS01135	COG1609	Transcriptional regulator
C1J03_RS01140	COG1653	transport
C1J03_RS01145	COG1175	transmembrane transport
C1J03_RS01150	COG0395	ABC-type sugar transport system, permease component
C1J03_RS01155	COG0366	Alpha amylase catalytic
C1J03_RS01160	COG3842	ATPase activity
C1J03_RS01170	COG1846	Transcriptional regulator
C1J03_RS01175	COG0709	Synthesizes selenophosphate from selenide and ATP
C1J03_RS01180	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
C1J03_RS01195	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C1J03_RS01200	COG3474	cytochrome
C1J03_RS01215	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1J03_RS01220	COG0509	glycine decarboxylation via glycine cleavage system
C1J03_RS01225	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C1J03_RS01225	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C1J03_RS01250	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
C1J03_RS01260	COG1917	Cupin 2, conserved barrel domain protein
C1J03_RS01265	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1J03_RS01275	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1J03_RS01280	COG3485	protocatechuate 3,4-dioxygenase
C1J03_RS01305	COG0778	Nitroreductase
C1J03_RS01310	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1J03_RS01320	COG1802	Transcriptional regulator
C1J03_RS01330	COG0318	PFAM AMP-dependent synthetase and ligase
C1J03_RS01340	COG1706	bacterial-type flagellum-dependent cell motility
C1J03_RS01365	COG2271	Major facilitator Superfamily
C1J03_RS01370	COG1054	Belongs to the UPF0176 family
C1J03_RS01375	COG1335	isochorismatase
C1J03_RS01390	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C1J03_RS01450	COG2099	Precorrin-6x reductase
C1J03_RS01465	COG2875	Belongs to the precorrin methyltransferase family
C1J03_RS01470	COG1797	cobyrinic acid a,c-diamide synthase activity
C1J03_RS01475	COG1648	precorrin-2 dehydrogenase activity
C1J03_RS01475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C1J03_RS01505	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
C1J03_RS01525	COG0514	ATP-dependent DNA helicase (RecQ)
C1J03_RS01530	COG3022	response to hydroperoxide
C1J03_RS01535	COG2205	protein histidine kinase activity
C1J03_RS01535	COG5002	protein histidine kinase activity
C1J03_RS01535	COG0784	Response regulator, receiver
C1J03_RS01540	COG2373	Large extracellular alpha-helical protein
C1J03_RS01545	COG4953	penicillin-binding protein 1C
C1J03_RS01565	COG0714	Associated with various cellular activities
C1J03_RS01575	COG3622	Belongs to the hyi family
C1J03_RS01590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1J03_RS01590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1J03_RS01610	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C1J03_RS01620	COG0793	Belongs to the peptidase S41A family
C1J03_RS01640	COG0129	dihydroxy-acid dehydratase activity
C1J03_RS01645	COG2274	protein secretion by the type I secretion system
C1J03_RS01655	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C1J03_RS01660	COG0285	dihydrofolate synthase activity
C1J03_RS01665	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C1J03_RS01675	COG2423	ornithine cyclodeaminase activity
C1J03_RS01685	COG1671	Belongs to the UPF0178 family
C1J03_RS01690	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C1J03_RS01695	COG0679	Auxin Efflux Carrier
C1J03_RS01715	COG2050	protein possibly involved in aromatic compounds catabolism
C1J03_RS01725	COG0791	NLP P60 protein
C1J03_RS01730	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C1J03_RS01740	COG0288	reversible hydration of carbon dioxide
C1J03_RS01760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1J03_RS01790	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C1J03_RS01810	COG1194	a g-specific adenine glycosylase
C1J03_RS01820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1J03_RS01825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C1J03_RS01830	COG1663	tetraacyldisaccharide 4'-kinase activity
C1J03_RS01835	COG1519	Transferase
C1J03_RS01850	COG0312	modulator of DNA gyrase
C1J03_RS01875	COG1196	nuclear chromosome segregation
C1J03_RS01875	COG3264	Mechanosensitive ion channel
C1J03_RS01905	COG0495	leucyl-tRNA aminoacylation
C1J03_RS01935	COG0745	RESPONSE REGULATOR receiver
C1J03_RS01950	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C1J03_RS01955	COG2835	tetraacyldisaccharide 4'-kinase activity
C1J03_RS01960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1J03_RS01970	COG0436	Aminotransferase
C1J03_RS01975	COG1674	ftsk spoiiie
C1J03_RS02000	COG0405	Gamma-glutamyltransferase
C1J03_RS02005	COG3920	Histidine kinase
C1J03_RS02040	COG1366	Belongs to the anti-sigma-factor antagonist family
C1J03_RS02085	COG0564	pseudouridine synthase activity
C1J03_RS02095	COG0450	alkyl hydroperoxide reductase
C1J03_RS02115	COG1185	polyribonucleotide nucleotidyltransferase activity
C1J03_RS02125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1J03_RS02135	COG1116	anion transmembrane transporter activity
C1J03_RS02140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1J03_RS02145	COG0513	Belongs to the DEAD box helicase family
C1J03_RS02160	COG0587	DNA-directed DNA polymerase activity
C1J03_RS02220	COG0825	malonyl-CoA metabolic process
C1J03_RS02240	COG4948	Mandelate Racemase Muconate Lactonizing
C1J03_RS02265	COG0469	pyruvate kinase activity
C1J03_RS02280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C1J03_RS02285	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C1J03_RS02290	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C1J03_RS02310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1J03_RS02310	COG0072	phenylalanine-tRNA ligase activity
C1J03_RS02320	COG0625	glutathione transferase activity
C1J03_RS02325	COG1970	mechanosensitive ion channel activity
C1J03_RS02330	COG0686	Belongs to the AlaDH PNT family
C1J03_RS02335	COG1522	sequence-specific DNA binding
C1J03_RS02350	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C1J03_RS02360	COG1122	ATPase activity
C1J03_RS02365	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C1J03_RS02370	COG1268	BioY protein
C1J03_RS02375	COG0183	Belongs to the thiolase family
C1J03_RS02380	COG1021	2,3-dihydroxybenzoate-AMP ligase
C1J03_RS02385	COG0604	alcohol dehydrogenase
C1J03_RS02385	COG3321	synthase
C1J03_RS02385	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS02400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C1J03_RS02405	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C1J03_RS02410	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C1J03_RS02415	COG2321	neutral zinc metallopeptidase
C1J03_RS02425	COG0737	Belongs to the 5'-nucleotidase family
C1J03_RS02430	COG2816	NAD+ diphosphatase activity
C1J03_RS02450	COG4166	transmembrane transport
C1J03_RS02455	COG4174	ABC transporter (Permease)
C1J03_RS02460	COG4239	(ABC) transporter, permease
C1J03_RS02465	COG4172	Belongs to the ABC transporter superfamily
C1J03_RS02470	COG0583	DNA-binding transcription factor activity
C1J03_RS02475	COG1686	Belongs to the peptidase S11 family
C1J03_RS02485	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C1J03_RS02500	COG0408	coproporphyrinogen oxidase activity
C1J03_RS02510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1J03_RS02525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1J03_RS02530	COG0596	Alpha beta hydrolase
C1J03_RS02565	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C1J03_RS02590	COG2151	metal-sulfur cluster biosynthetic enzyme
C1J03_RS02590	COG0489	protein tyrosine kinase activity
C1J03_RS02595	COG0254	rRNA binding
C1J03_RS02600	COG0335	large ribosomal subunit rRNA binding
C1J03_RS02605	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C1J03_RS02610	COG0336	Belongs to the RNA methyltransferase TrmD family
C1J03_RS02625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C1J03_RS02630	COG0778	Nitroreductase
C1J03_RS02635	COG0228	four-way junction DNA binding
C1J03_RS02650	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C1J03_RS02675	COG0356	it plays a direct role in the translocation of protons across the membrane
C1J03_RS02680	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C1J03_RS02685	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C1J03_RS02690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C1J03_RS02695	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C1J03_RS02700	COG2186	Transcriptional regulator
C1J03_RS02730	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C1J03_RS02745	COG0435	Glutathione S-transferase
C1J03_RS02750	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C1J03_RS02755	COG0242	peptide deformylase activity
C1J03_RS02760	COG0242	peptide deformylase activity
C1J03_RS02765	COG0242	peptide deformylase activity
C1J03_RS02770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C1J03_RS02780	COG2860	membrane
C1J03_RS02785	COG0328	RNA-DNA hybrid ribonuclease activity
C1J03_RS02790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1J03_RS02795	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C1J03_RS02800	COG2197	response regulator
C1J03_RS02810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C1J03_RS02815	COG1758	RNA polymerase activity
C1J03_RS02830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C1J03_RS02835	COG0736	holo-[acyl-carrier-protein] synthase activity
C1J03_RS02840	COG0681	Belongs to the peptidase S26 family
C1J03_RS02845	COG0571	ribonuclease III activity
C1J03_RS02850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C1J03_RS02860	COG1381	Involved in DNA repair and RecF pathway recombination
C1J03_RS02885	COG1396	sequence-specific DNA binding
C1J03_RS02900	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C1J03_RS02905	COG0745	RESPONSE REGULATOR receiver
C1J03_RS02910	COG2205	protein histidine kinase activity
C1J03_RS02915	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C1J03_RS02920	COG1660	Displays ATPase and GTPase activities
C1J03_RS02940	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1J03_RS02960	COG2096	Adenosyltransferase
C1J03_RS02970	COG0300	oxidoreductase activity
C1J03_RS02980	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C1J03_RS02995	COG2124	cytochrome p450
C1J03_RS02995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C1J03_RS03005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C1J03_RS03045	COG0596	Alpha beta hydrolase
C1J03_RS03150	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1J03_RS03155	COG0250	Participates in transcription elongation, termination and antitermination
C1J03_RS03160	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C1J03_RS03165	COG0081	regulation of translation
C1J03_RS03170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C1J03_RS03175	COG0222	ribosome binding
C1J03_RS03180	COG0085	RNA polymerase activity
C1J03_RS03185	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C1J03_RS03205	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C1J03_RS03210	COG0049	tRNA binding
C1J03_RS03215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C1J03_RS03220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C1J03_RS03235	COG0051	transcription antitermination factor activity, RNA binding
C1J03_RS03240	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C1J03_RS03245	COG0088	Forms part of the polypeptide exit tunnel
C1J03_RS03250	COG0089	rRNA binding
C1J03_RS03255	COG1278	Cold shock
C1J03_RS03270	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C1J03_RS03275	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C1J03_RS03280	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C1J03_RS03285	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C1J03_RS03290	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C1J03_RS03305	COG0255	Belongs to the universal ribosomal protein uL29 family
C1J03_RS03310	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C1J03_RS03315	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C1J03_RS03320	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C1J03_RS03325	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C1J03_RS03330	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C1J03_RS03335	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C1J03_RS03340	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C1J03_RS03345	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C1J03_RS03350	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C1J03_RS03355	COG1841	ribosomal large subunit assembly
C1J03_RS03365	COG0200	Binds to the 23S rRNA
C1J03_RS03370	COG0201	protein transport
C1J03_RS03375	COG0563	adenylate kinase activity
C1J03_RS03385	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C1J03_RS03390	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C1J03_RS03395	COG0202	RNA polymerase activity
C1J03_RS03400	COG0203	ribosomal protein L17
C1J03_RS03405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C1J03_RS03410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C1J03_RS03415	COG0564	pseudouridine synthase activity
C1J03_RS03420	COG0546	phosphoglycolate phosphatase activity
C1J03_RS03430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1J03_RS03435	COG4597	amino acid ABC transporter
C1J03_RS03440	COG0765	amino acid transport
C1J03_RS03445	COG1126	abc transporter atp-binding protein
C1J03_RS03460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C1J03_RS03465	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C1J03_RS03475	COG0706	membrane insertase activity
C1J03_RS03485	COG0037	tRNA processing
C1J03_RS03490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C1J03_RS03495	COG0594	ribonuclease P activity
C1J03_RS03500	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C1J03_RS03510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1J03_RS03515	COG4191	Histidine kinase
C1J03_RS03555	COG3254	rhamnose metabolic process
C1J03_RS03560	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS03565	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS03570	COG1129	ABC transporter
C1J03_RS03585	COG3347	Dehydrogenase
C1J03_RS03585	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS03590	COG4952	isomerase
C1J03_RS03610	COG0346	lactoylglutathione lyase activity
C1J03_RS03625	COG1741	Belongs to the pirin family
C1J03_RS03630	COG1741	Belongs to the pirin family
C1J03_RS03655	COG2826	transposase and inactivated derivatives, IS30 family
C1J03_RS03660	COG0668	transmembrane transport
C1J03_RS03665	COG2207	Transcriptional regulator
C1J03_RS03705	COG3119	arylsulfatase activity
C1J03_RS03740	COG2826	transposase and inactivated derivatives, IS30 family
C1J03_RS03745	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS03760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1J03_RS03765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1J03_RS03785	COG2010	Cytochrome c
C1J03_RS03790	COG0348	domain, Protein
C1J03_RS03830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1J03_RS03840	COG1335	isochorismatase
C1J03_RS03890	COG0789	Transcriptional regulator
C1J03_RS03920	COG4191	Histidine kinase
C1J03_RS03920	COG0784	Response regulator, receiver
C1J03_RS03925	COG0589	response to stress
C1J03_RS03965	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
C1J03_RS03970	COG1609	Transcriptional regulator
C1J03_RS03975	COG2115	Belongs to the xylose isomerase family
C1J03_RS03985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1J03_RS03990	COG0745	RESPONSE REGULATOR receiver
C1J03_RS03995	COG2205	protein histidine kinase activity
C1J03_RS04000	COG1271	oxidase subunit
C1J03_RS04005	COG1294	oxidase, subunit
C1J03_RS04015	COG3321	synthase
C1J03_RS04015	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS04015	COG0604	alcohol dehydrogenase
C1J03_RS04025	COG1131	(ABC) transporter
C1J03_RS04030	COG0842	Transport permease protein
C1J03_RS04055	COG0322	excinuclease ABC activity
C1J03_RS04060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C1J03_RS04070	COG0314	molybdopterin synthase activity
C1J03_RS04080	COG2885	chlorophyll binding
C1J03_RS04085	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C1J03_RS04090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C1J03_RS04125	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C1J03_RS04145	COG0540	Belongs to the ATCase OTCase family
C1J03_RS04150	COG1573	uracil-dna glycosylase
C1J03_RS04155	COG1280	lysine exporter protein (LysE YggA)
C1J03_RS04160	COG0521	Mo-molybdopterin cofactor biosynthetic process
C1J03_RS04170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1J03_RS04180	COG1678	Uncharacterized ACR, COG1678
C1J03_RS04185	COG0009	L-threonylcarbamoyladenylate synthase
C1J03_RS04190	COG1960	acyl-CoA dehydrogenase activity
C1J03_RS04235	COG0746	molybdenum cofactor guanylyltransferase activity
C1J03_RS04240	COG1763	Mo-molybdopterin cofactor biosynthetic process
C1J03_RS04245	COG0303	'Molybdopterin
C1J03_RS04260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1J03_RS04270	COG0789	Transcriptional regulator
C1J03_RS04290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C1J03_RS04295	COG0142	geranyltranstransferase activity
C1J03_RS04320	COG0583	DNA-binding transcription factor activity
C1J03_RS04325	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS04335	COG2200	EAL domain
C1J03_RS04340	COG2818	Glycosylase
C1J03_RS04345	COG0402	S-adenosylhomocysteine deaminase activity
C1J03_RS04350	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C1J03_RS04360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C1J03_RS04365	COG0287	Prephenate dehydrogenase
C1J03_RS04380	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C1J03_RS04405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1J03_RS04420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C1J03_RS04430	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C1J03_RS04435	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C1J03_RS04440	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C1J03_RS04445	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C1J03_RS04450	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C1J03_RS04480	COG2983	Belongs to the UPF0260 family
C1J03_RS04485	COG0196	riboflavin kinase activity
C1J03_RS04490	COG2030	dehydratase
C1J03_RS04515	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C1J03_RS04520	COG0459	protein refolding
C1J03_RS04540	COG3454	Phosphonate metabolism
C1J03_RS04545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C1J03_RS04550	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C1J03_RS04560	COG0071	Belongs to the small heat shock protein (HSP20) family
C1J03_RS04575	COG2046	Belongs to the sulfate adenylyltransferase family
C1J03_RS04575	COG0529	Catalyzes the synthesis of activated sulfate
C1J03_RS04580	COG0492	ferredoxin-NADP+ reductase activity
C1J03_RS04585	COG1522	sequence-specific DNA binding
C1J03_RS04605	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C1J03_RS04625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1J03_RS04630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1J03_RS04635	COG1435	thymidine kinase activity
C1J03_RS04645	COG0431	NADPH-dependent FMN reductase
C1J03_RS04655	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C1J03_RS04670	COG1566	PFAM secretion protein HlyD family protein
C1J03_RS04675	COG2226	methyltransferase
C1J03_RS04680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C1J03_RS04685	COG0596	Alpha beta hydrolase
C1J03_RS04700	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C1J03_RS04705	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C1J03_RS04730	COG0281	malic enzyme
C1J03_RS04730	COG0280	phosphate acetyltransferase
C1J03_RS04735	COG0295	cytidine deaminase activity
C1J03_RS04740	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C1J03_RS04745	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C1J03_RS04750	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C1J03_RS04770	COG0318	PFAM AMP-dependent synthetase and ligase
C1J03_RS04790	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1J03_RS04790	COG1024	Enoyl-CoA hydratase
C1J03_RS04800	COG0183	Belongs to the thiolase family
C1J03_RS04805	COG0625	glutathione transferase activity
C1J03_RS04815	COG1960	acyl-CoA dehydrogenase activity
C1J03_RS04820	COG0789	Transcriptional regulator
C1J03_RS04825	COG2197	response regulator
C1J03_RS04850	COG0534	Mate efflux family protein
C1J03_RS04870	COG0737	Belongs to the 5'-nucleotidase family
C1J03_RS04875	COG2135	peptidase activity
C1J03_RS04885	COG0583	DNA-binding transcription factor activity
C1J03_RS04890	COG1960	acyl-CoA dehydrogenase activity
C1J03_RS04895	COG3842	ATPase activity
C1J03_RS04905	COG1175	transmembrane transport
C1J03_RS04910	COG0395	ABC-type sugar transport system, permease component
C1J03_RS04920	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1J03_RS04975	COG4948	Mandelate Racemase Muconate Lactonizing
C1J03_RS04990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C1J03_RS05010	COG1047	Peptidyl-prolyl cis-trans
C1J03_RS05025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C1J03_RS05035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1J03_RS05040	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C1J03_RS05045	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C1J03_RS05050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C1J03_RS05055	COG2188	Transcriptional regulator
C1J03_RS05060	COG2971	BadF BadG BcrA BcrD
C1J03_RS05065	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C1J03_RS05075	COG1175	transmembrane transport
C1J03_RS05080	COG0395	ABC-type sugar transport system, permease component
C1J03_RS05085	COG0673	inositol 2-dehydrogenase activity
C1J03_RS05110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C1J03_RS05115	COG2885	chlorophyll binding
C1J03_RS05125	COG1702	phosphate starvation-inducible protein PhoH
C1J03_RS05130	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C1J03_RS05135	COG1253	flavin adenine dinucleotide binding
C1J03_RS05140	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C1J03_RS05145	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C1J03_RS05150	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C1J03_RS05155	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C1J03_RS05160	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C1J03_RS05175	COG0539	negative regulation of cytoplasmic translation
C1J03_RS05180	COG0776	regulation of translation
C1J03_RS05190	COG0135	phosphoribosylanthranilate isomerase activity
C1J03_RS05200	COG0133	tryptophan synthase activity
C1J03_RS05205	COG0517	IMP dehydrogenase activity
C1J03_RS05205	COG1994	Peptidase M50
C1J03_RS05230	COG0193	aminoacyl-tRNA hydrolase activity
C1J03_RS05240	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C1J03_RS05255	COG1304	FMN binding
C1J03_RS05260	COG0159	tryptophan synthase activity
C1J03_RS05270	COG0012	GTP binding
C1J03_RS05280	COG0668	transmembrane transport
C1J03_RS05285	COG3119	arylsulfatase activity
C1J03_RS05290	COG0583	DNA-binding transcription factor activity
C1J03_RS05375	COG3550	peptidyl-serine autophosphorylation
C1J03_RS05380	COG0210	DNA helicase
C1J03_RS05410	COG2207	Transcriptional regulator
C1J03_RS05415	COG3119	arylsulfatase activity
C1J03_RS05450	COG1175	transmembrane transport
C1J03_RS05455	COG0395	ABC-type sugar transport system, permease component
C1J03_RS05465	COG3842	ATPase activity
C1J03_RS05480	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C1J03_RS05490	COG3707	response regulator
C1J03_RS05500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1J03_RS05505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1J03_RS05510	COG1116	anion transmembrane transporter activity
C1J03_RS05515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1J03_RS05525	COG0243	molybdopterin cofactor binding
C1J03_RS05530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C1J03_RS05535	COG1648	precorrin-2 dehydrogenase activity
C1J03_RS05535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C1J03_RS05545	COG0583	DNA-binding transcription factor activity
C1J03_RS05595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1J03_RS05615	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS05625	COG0251	oxidation-reduction process
C1J03_RS05650	COG2826	transposase and inactivated derivatives, IS30 family
C1J03_RS05665	COG1360	Flagellar Motor Protein
C1J03_RS05730	COG1959	2 iron, 2 sulfur cluster binding
C1J03_RS05745	COG1454	alcohol dehydrogenase
C1J03_RS05765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C1J03_RS05785	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS05815	COG1538	Outer membrane efflux protein
C1J03_RS05820	COG2274	protein secretion by the type I secretion system
C1J03_RS05865	COG0489	protein tyrosine kinase activity
C1J03_RS05905	COG3383	formate dehydrogenase (NAD+) activity
C1J03_RS05905	COG0243	molybdopterin cofactor binding
C1J03_RS05910	COG0437	4 iron, 4 sulfur cluster binding
C1J03_RS05920	COG2204	response regulator
C1J03_RS05925	COG4191	Histidine kinase
C1J03_RS05930	COG0583	DNA-binding transcription factor activity
C1J03_RS05945	COG1741	Belongs to the pirin family
C1J03_RS05960	COG2226	methyltransferase
C1J03_RS05980	COG0668	transmembrane transport
C1J03_RS05985	COG1840	ABC-type Fe3 transport system, periplasmic component
C1J03_RS05995	COG3842	ATPase activity
C1J03_RS06000	COG0483	inositol monophosphate 1-phosphatase activity
C1J03_RS06015	COG1283	sodium-dependent phosphate transmembrane transporter activity
C1J03_RS06025	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS06030	COG0174	glutamine synthetase
C1J03_RS06065	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS06070	COG0673	inositol 2-dehydrogenase activity
C1J03_RS06080	COG1082	Xylose isomerase domain protein TIM barrel
C1J03_RS06090	COG4948	Mandelate Racemase Muconate Lactonizing
C1J03_RS06100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1J03_RS06105	COG3842	ATPase activity
C1J03_RS06110	COG3842	ATPase activity
C1J03_RS06120	COG0395	ABC-type sugar transport system, permease component
C1J03_RS06125	COG1175	transmembrane transport
C1J03_RS06135	COG5441	Belongs to the UPF0261 family
C1J03_RS06140	COG5564	TIM-barrel signal transduction protein
C1J03_RS06150	COG0024	Methionine aminopeptidase
C1J03_RS06155	COG1858	cytochrome C peroxidase
C1J03_RS06165	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1J03_RS06185	COG4989	oxidoreductase activity
C1J03_RS06210	COG2197	response regulator
C1J03_RS06230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1J03_RS06240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1J03_RS06280	COG0101	tRNA pseudouridine synthase activity
C1J03_RS06285	COG3106	COG3106 Predicted ATPase
C1J03_RS06295	COG3768	UPF0283 membrane protein
C1J03_RS06305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C1J03_RS06310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C1J03_RS06315	COG1183	phosphatidylcholine synthase activity
C1J03_RS06325	COG4974	Belongs to the 'phage' integrase family
C1J03_RS06335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C1J03_RS06375	COG0632	four-way junction helicase activity
C1J03_RS06380	COG2255	four-way junction helicase activity
C1J03_RS06390	COG0824	Thioesterase
C1J03_RS06400	COG0848	biopolymer transport protein
C1J03_RS06410	COG0823	Involved in the tonB-independent uptake of proteins
C1J03_RS06415	COG2885	chlorophyll binding
C1J03_RS06425	COG0037	tRNA processing
C1J03_RS06430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C1J03_RS06445	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C1J03_RS06455	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C1J03_RS06470	COG1201	RNA secondary structure unwinding
C1J03_RS06525	COG4964	Belongs to the GSP D family
C1J03_RS06540	COG0741	lytic transglycosylase activity
C1J03_RS06545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C1J03_RS06560	COG1754	DNA topoisomerase type I activity
C1J03_RS06560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1J03_RS06565	COG0758	DNA mediated transformation
C1J03_RS06570	COG0312	modulator of DNA gyrase
C1J03_RS06580	COG0109	protoheme IX farnesyltransferase activity
C1J03_RS06590	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C1J03_RS06600	COG3346	SURF1 family
C1J03_RS06630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C1J03_RS06640	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C1J03_RS06645	COG0659	secondary active sulfate transmembrane transporter activity
C1J03_RS06675	COG4149	molybdate abc transporter
C1J03_RS06680	COG0725	ABC transporter, periplasmic molybdate-binding protein
C1J03_RS06710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C1J03_RS06735	COG0601	transmembrane transport
C1J03_RS06740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1J03_RS06745	COG4172	Belongs to the ABC transporter superfamily
C1J03_RS06750	COG0583	DNA-binding transcription factor activity
C1J03_RS06765	COG3119	arylsulfatase activity
C1J03_RS06770	COG2207	Transcriptional regulator
C1J03_RS06775	COG0668	transmembrane transport
C1J03_RS06780	COG0668	transmembrane transport
C1J03_RS06785	COG4638	Rieske (2fe-2S)
C1J03_RS06790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1J03_RS06800	COG1802	Transcriptional regulator
C1J03_RS06820	COG0625	glutathione transferase activity
C1J03_RS06835	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C1J03_RS06850	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C1J03_RS06850	COG3608	succinylglutamate desuccinylase aspartoacylase
C1J03_RS06900	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
C1J03_RS06925	COG0697	spore germination
C1J03_RS06960	COG4983	Phage plasmid primase, P4 family domain protein
C1J03_RS06970	COG0647	UMP catabolic process
C1J03_RS06980	COG3842	ATPase activity
C1J03_RS06985	COG1178	ABC-type Fe3 transport system permease component
C1J03_RS06990	COG1672	PFAM Archaeal ATPase
C1J03_RS06990	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
C1J03_RS07025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1J03_RS07035	COG0745	RESPONSE REGULATOR receiver
C1J03_RS07080	COG3550	peptidyl-serine autophosphorylation
C1J03_RS07100	COG0747	negative chemotaxis
C1J03_RS07105	COG0601	transmembrane transport
C1J03_RS07110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1J03_RS07115	COG0444	Belongs to the ABC transporter superfamily
C1J03_RS07140	COG0741	lytic transglycosylase activity
C1J03_RS07155	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS07160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1J03_RS07175	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1J03_RS07180	COG0022	dehydrogenase e1 component
C1J03_RS07185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C1J03_RS07190	COG0006	proline dipeptidase activity
C1J03_RS07205	COG1879	ABC-type sugar transport system periplasmic component
C1J03_RS07215	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS07220	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS07225	COG1129	ABC transporter
C1J03_RS07255	COG0420	3'-5' exonuclease activity
C1J03_RS07275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1J03_RS07305	COG1538	Outer membrane efflux protein
C1J03_RS07315	COG1492	cobalamin metabolic process
C1J03_RS07325	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C1J03_RS07330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1J03_RS07340	COG1132	(ABC) transporter
C1J03_RS07345	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C1J03_RS07355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C1J03_RS07370	COG0525	valine-tRNA ligase activity
C1J03_RS07395	COG0583	DNA-binding transcription factor activity
C1J03_RS07400	COG2130	NADP-dependent
C1J03_RS07405	COG0483	inositol monophosphate 1-phosphatase activity
C1J03_RS07420	COG0506	proline dehydrogenase activity
C1J03_RS07420	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C1J03_RS07420	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C1J03_RS07425	COG1522	sequence-specific DNA binding
C1J03_RS07440	COG0582	viral genome integration into host DNA
C1J03_RS07495	COG1609	Transcriptional regulator
C1J03_RS07500	COG1653	transport
C1J03_RS07505	COG1175	transmembrane transport
C1J03_RS07510	COG3833	ABC-type maltose transport systems, permease component
C1J03_RS07535	COG0673	inositol 2-dehydrogenase activity
C1J03_RS07575	COG1573	uracil-dna glycosylase
C1J03_RS07590	COG0840	transmembrane signaling receptor activity
C1J03_RS07595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1J03_RS07600	COG2814	Major facilitator Superfamily
C1J03_RS07605	COG0667	Aldo Keto reductase
C1J03_RS07610	COG3246	L-lysine catabolic process to acetate
C1J03_RS07620	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1J03_RS07620	COG0824	Thioesterase
C1J03_RS07705	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS07710	COG3976	FMN-binding domain protein
C1J03_RS07710	COG1053	succinate dehydrogenase
C1J03_RS07740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1J03_RS07795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C1J03_RS07815	COG1741	Belongs to the pirin family
C1J03_RS07845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C1J03_RS07855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1J03_RS07860	COG4311	Sarcosine oxidase, delta subunit
C1J03_RS07865	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1J03_RS07865	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1J03_RS07885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1J03_RS07895	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C1J03_RS07900	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1J03_RS07900	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1J03_RS07930	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C1J03_RS07935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C1J03_RS07980	COG0564	pseudouridine synthase activity
C1J03_RS08015	COG1793	dna ligase
C1J03_RS08045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C1J03_RS08050	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C1J03_RS08055	COG1329	Transcriptional regulator
C1J03_RS08060	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C1J03_RS08065	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C1J03_RS08075	COG1522	sequence-specific DNA binding
C1J03_RS08090	COG2873	o-acetylhomoserine
C1J03_RS08125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1J03_RS08135	COG1832	CoA-binding protein
C1J03_RS08140	COG0140	phosphoribosyl-ATP diphosphatase activity
C1J03_RS08145	COG0107	imidazoleglycerol-phosphate synthase activity
C1J03_RS08150	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C1J03_RS08170	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C1J03_RS08175	COG0131	Imidazoleglycerol-phosphate dehydratase
C1J03_RS08195	COG0346	lactoylglutathione lyase activity
C1J03_RS08200	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C1J03_RS08220	COG0489	protein tyrosine kinase activity
C1J03_RS08230	COG2001	Belongs to the MraZ family
C1J03_RS08235	COG0275	rRNA processing
C1J03_RS08250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C1J03_RS08260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1J03_RS08265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C1J03_RS08270	COG2081	HI0933 family
C1J03_RS08280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C1J03_RS08285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C1J03_RS08305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C1J03_RS08310	COG1181	Belongs to the D-alanine--D-alanine ligase family
C1J03_RS08315	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C1J03_RS08320	COG0849	cell division
C1J03_RS08325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C1J03_RS08335	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1J03_RS08380	COG0484	heat shock protein binding
C1J03_RS08400	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C1J03_RS08425	COG0308	aminopeptidase N
C1J03_RS08430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C1J03_RS08440	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C1J03_RS08445	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS08460	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C1J03_RS08475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1J03_RS08480	COG0601	transmembrane transport
C1J03_RS08505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1J03_RS08510	COG1473	amidohydrolase
C1J03_RS08515	COG1473	amidohydrolase
C1J03_RS08520	COG0438	transferase activity, transferring glycosyl groups
C1J03_RS08525	COG1519	Transferase
C1J03_RS08530	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C1J03_RS08545	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C1J03_RS08550	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C1J03_RS08555	COG0546	phosphoglycolate phosphatase activity
C1J03_RS08565	COG1960	acyl-CoA dehydrogenase activity
C1J03_RS08570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1J03_RS08580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C1J03_RS08605	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C1J03_RS08610	COG2826	transposase and inactivated derivatives, IS30 family
C1J03_RS08625	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1J03_RS08630	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1J03_RS08635	COG0649	NAD binding
C1J03_RS08645	COG3743	rRNA binding
C1J03_RS08645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C1J03_RS08700	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C1J03_RS08705	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1J03_RS08720	COG0713	ATP synthesis coupled electron transport
C1J03_RS08735	COG1007	ATP synthesis coupled electron transport
C1J03_RS08745	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C1J03_RS08765	COG0513	Belongs to the DEAD box helicase family
C1J03_RS08775	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C1J03_RS08790	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS08795	COG4335	DNA alkylation repair
C1J03_RS08825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1J03_RS08830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1J03_RS08835	COG0805	protein transport
C1J03_RS08845	COG0739	heme binding
C1J03_RS08845	COG1388	LysM domain
C1J03_RS08850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C1J03_RS08855	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C1J03_RS08860	COG4221	oxidoreductase activity
C1J03_RS08875	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C1J03_RS08900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1J03_RS08920	COG0305	Participates in initiation and elongation during chromosome replication
C1J03_RS08925	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C1J03_RS08930	COG0418	dihydroorotase activity
C1J03_RS08965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C1J03_RS08975	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C1J03_RS08980	COG0583	DNA-binding transcription factor activity
C1J03_RS08995	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C1J03_RS09000	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C1J03_RS09005	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
C1J03_RS09020	COG1138	Cytochrome C-type biogenesis protein
C1J03_RS09025	COG3088	subunit of a heme lyase
C1J03_RS09030	COG1024	Enoyl-CoA hydratase
C1J03_RS09045	COG0372	Belongs to the citrate synthase family
C1J03_RS09050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C1J03_RS09055	COG0658	competence protein
C1J03_RS09055	COG2333	competence protein COMEC
C1J03_RS09060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C1J03_RS09065	COG0303	'Molybdopterin
C1J03_RS09070	COG0315	cyclic pyranopterin monophosphate synthase activity
C1J03_RS09080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C1J03_RS09085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C1J03_RS09105	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1J03_RS09115	COG0436	Aminotransferase
C1J03_RS09120	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
C1J03_RS09130	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C1J03_RS09135	COG0259	pyridoxamine-phosphate oxidase activity
C1J03_RS09155	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1J03_RS09170	COG1238	metal cluster binding
C1J03_RS09185	COG0395	ABC-type sugar transport system, permease component
C1J03_RS09195	COG3842	ATPase activity
C1J03_RS09200	COG3842	ATPase activity
C1J03_RS09210	COG1349	DNA-binding transcription factor activity
C1J03_RS09215	COG1162	GTPase activity
C1J03_RS09250	COG0215	cysteine-tRNA ligase activity
C1J03_RS09255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C1J03_RS09270	COG2814	Major facilitator Superfamily
C1J03_RS09320	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C1J03_RS09330	COG0018	arginyl-trna synthetase
C1J03_RS09340	COG1472	Belongs to the glycosyl hydrolase 3 family
C1J03_RS09345	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C1J03_RS09350	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C1J03_RS09360	COG0717	Belongs to the dCTP deaminase family
C1J03_RS09375	COG0776	regulation of translation
C1J03_RS09380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1J03_RS09385	COG0416	fatty acid biosynthetic process
C1J03_RS09390	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C1J03_RS09410	COG0488	(ABC) transporter
C1J03_RS09425	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C1J03_RS09430	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C1J03_RS09450	COG0148	phosphopyruvate hydratase activity
C1J03_RS09470	COG0513	Belongs to the DEAD box helicase family
C1J03_RS09480	COG0697	spore germination
C1J03_RS09485	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C1J03_RS09490	COG0454	-acetyltransferase
C1J03_RS09490	COG0456	acetyltransferase
C1J03_RS09500	COG3956	TIGRFAM MazG family protein
C1J03_RS09505	COG1473	amidohydrolase
C1J03_RS09510	COG0010	Belongs to the arginase family
C1J03_RS09530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C1J03_RS09535	COG2890	protein-(glutamine-N5) methyltransferase activity
C1J03_RS09550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C1J03_RS09555	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C1J03_RS09565	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C1J03_RS09580	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C1J03_RS09590	COG3577	Aspartyl protease
C1J03_RS09595	COG2095	MarC family integral membrane protein
C1J03_RS09600	COG0488	(ABC) transporter
C1J03_RS09605	COG0105	UTP biosynthetic process
C1J03_RS09630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C1J03_RS09660	COG1126	abc transporter atp-binding protein
C1J03_RS09665	COG0765	amino acid transport
C1J03_RS09670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C1J03_RS09715	COG2326	polyphosphate kinase activity
C1J03_RS09730	COG0745	RESPONSE REGULATOR receiver
C1J03_RS09745	COG3064	Membrane
C1J03_RS09750	COG3128	pkhd-type hydroxylase
C1J03_RS09775	COG2826	transposase and inactivated derivatives, IS30 family
C1J03_RS09780	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS09795	COG0277	FAD linked oxidase domain protein
C1J03_RS09810	COG2070	2-Nitropropane dioxygenase
C1J03_RS09815	COG2070	2-Nitropropane dioxygenase
C1J03_RS09845	COG1136	(ABC) transporter
C1J03_RS09845	COG0577	efflux transmembrane transporter activity
C1J03_RS09850	COG1136	(ABC) transporter
C1J03_RS09850	COG0577	efflux transmembrane transporter activity
C1J03_RS09860	COG0735	belongs to the Fur family
C1J03_RS09870	COG0559	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS09875	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS09880	COG0411	ABC transporter
C1J03_RS09910	COG1672	PFAM Archaeal ATPase
C1J03_RS09910	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
C1J03_RS09935	COG1733	regulation of RNA biosynthetic process
C1J03_RS09960	COG2826	transposase and inactivated derivatives, IS30 family
C1J03_RS09970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1J03_RS09990	COG2274	protein secretion by the type I secretion system
C1J03_RS09995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1J03_RS10030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1J03_RS10030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1J03_RS10045	COG3311	Transcriptional regulator
C1J03_RS10050	COG1569	PIN domain
C1J03_RS10110	COG2925	Exonuclease
C1J03_RS10140	COG1061	Type III restriction enzyme res subunit
C1J03_RS10200	COG1196	nuclear chromosome segregation
C1J03_RS10200	COG0741	lytic transglycosylase activity
C1J03_RS10200	COG0739	heme binding
C1J03_RS10205	COG3451	type IV secretory pathway VirB4
C1J03_RS10220	COG0741	lytic transglycosylase activity
C1J03_RS10245	COG0402	S-adenosylhomocysteine deaminase activity
C1J03_RS10375	COG3657	addiction module killer protein
C1J03_RS10410	COG2130	NADP-dependent
C1J03_RS10445	COG0596	Alpha beta hydrolase
C1J03_RS10460	COG1902	pentaerythritol trinitrate reductase activity
C1J03_RS10465	COG0583	DNA-binding transcription factor activity
C1J03_RS10495	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C1J03_RS10500	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C1J03_RS10505	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C1J03_RS10515	COG2166	iron-sulfur cluster assembly
C1J03_RS10530	COG0393	Putative heavy-metal-binding
C1J03_RS10540	COG5012	cobalamin binding
C1J03_RS10550	COG0646	methionine synthase
C1J03_RS10550	COG1410	methionine synthase
C1J03_RS10560	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C1J03_RS10565	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C1J03_RS10570	COG0047	phosphoribosylformylglycinamidine synthase activity
C1J03_RS10580	COG2204	response regulator
C1J03_RS10595	COG1530	ribonuclease E activity
C1J03_RS10600	COG0425	Belongs to the sulfur carrier protein TusA family
C1J03_RS10605	COG0785	Cytochrome C biogenesis protein
C1J03_RS10620	COG3588	fructose-bisphosphate aldolase
C1J03_RS10635	COG0114	fumarate hydratase activity
C1J03_RS10645	COG2059	Chromate
C1J03_RS10685	COG2318	DinB family
C1J03_RS10690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1J03_RS10695	COG0604	alcohol dehydrogenase
C1J03_RS10700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C1J03_RS10705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C1J03_RS10710	COG0415	Belongs to the DNA photolyase family
C1J03_RS10715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C1J03_RS10725	COG0494	nUDIX hydrolase
C1J03_RS10735	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C1J03_RS10735	COG3264	Mechanosensitive ion channel
C1J03_RS10740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C1J03_RS10800	COG2267	carboxylic ester hydrolase activity
C1J03_RS10810	COG2072	flavoprotein involved in K transport
C1J03_RS10915	COG3813	Protein conserved in bacteria
C1J03_RS10945	COG0318	PFAM AMP-dependent synthetase and ligase
C1J03_RS10950	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS10970	COG1609	Transcriptional regulator
C1J03_RS10975	COG2515	1-aminocyclopropane-1-carboxylate deaminase
C1J03_RS11035	COG0811	peptide transport
C1J03_RS11050	COG2832	Protein of unknown function (DUF454)
C1J03_RS11055	COG1959	2 iron, 2 sulfur cluster binding
C1J03_RS11100	COG0789	Transcriptional regulator
C1J03_RS11130	COG2010	Cytochrome c
C1J03_RS11140	COG0582	viral genome integration into host DNA
C1J03_RS11185	COG4974	Belongs to the 'phage' integrase family
C1J03_RS11190	COG0517	IMP dehydrogenase activity
C1J03_RS11235	COG3743	rRNA binding
C1J03_RS11235	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C1J03_RS11240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C1J03_RS11245	COG1280	lysine exporter protein (LysE YggA)
C1J03_RS11255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C1J03_RS11260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C1J03_RS11265	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C1J03_RS11300	COG0052	Belongs to the universal ribosomal protein uS2 family
C1J03_RS11305	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C1J03_RS11325	COG2771	luxR family
C1J03_RS11330	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C1J03_RS11350	COG0745	RESPONSE REGULATOR receiver
C1J03_RS11355	COG0704	Plays a role in the regulation of phosphate uptake
C1J03_RS11360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C1J03_RS11370	COG0573	inorganic phosphate transmembrane transporter activity
C1J03_RS11380	COG5002	protein histidine kinase activity
C1J03_RS11390	COG0194	GDP metabolic process
C1J03_RS11395	COG1561	YicC-like family, N-terminal region
C1J03_RS11405	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C1J03_RS11445	COG0433	COG0433 Predicted ATPase
C1J03_RS11465	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1J03_RS11480	COG3971	2-oxopent-4-enoate hydratase activity
C1J03_RS11485	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1J03_RS11500	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS11515	COG5441	Belongs to the UPF0261 family
C1J03_RS11520	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS11545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1J03_RS11550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1J03_RS11555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C1J03_RS11565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C1J03_RS11580	COG0719	Fe-S assembly protein
C1J03_RS11585	COG0396	ATPase activity
C1J03_RS11600	COG0719	Fe-S assembly protein
C1J03_RS11610	COG1959	2 iron, 2 sulfur cluster binding
C1J03_RS11615	COG2945	thiolester hydrolase activity
C1J03_RS11630	COG0538	isocitrate dehydrogenase activity
C1J03_RS11635	COG0121	glutamine amidotransferase
C1J03_RS11645	COG1522	sequence-specific DNA binding
C1J03_RS11650	COG2076	Multidrug Resistance protein
C1J03_RS11655	COG1217	gtp-binding protein TYPA
C1J03_RS11665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C1J03_RS11670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C1J03_RS11700	COG2264	protein methyltransferase activity
C1J03_RS11760	COG1126	abc transporter atp-binding protein
C1J03_RS11765	COG0765	amino acid transport
C1J03_RS11790	COG0668	transmembrane transport
C1J03_RS11815	COG3152	Membrane
C1J03_RS11845	COG1733	regulation of RNA biosynthetic process
C1J03_RS11875	COG1686	Belongs to the peptidase S11 family
C1J03_RS11880	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C1J03_RS11895	COG0084	hydrolase, TatD family'
C1J03_RS11900	COG1234	tRNA 3'-trailer cleavage
C1J03_RS11910	COG1609	Transcriptional regulator
C1J03_RS11925	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1J03_RS11930	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1J03_RS11930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1J03_RS11935	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1J03_RS11940	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS11965	COG1304	FMN binding
C1J03_RS11970	COG1609	Transcriptional regulator
C1J03_RS11980	COG0028	Belongs to the TPP enzyme family
C1J03_RS12005	COG0069	glutamate synthase activity
C1J03_RS12015	COG2226	methyltransferase
C1J03_RS12025	COG1309	transcriptional regulator
C1J03_RS12040	COG0596	Alpha beta hydrolase
C1J03_RS12100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1J03_RS12105	COG0489	protein tyrosine kinase activity
C1J03_RS12105	COG3206	protein involved in exopolysaccharide biosynthesis
C1J03_RS12115	COG0438	transferase activity, transferring glycosyl groups
C1J03_RS12145	COG0438	transferase activity, transferring glycosyl groups
C1J03_RS12165	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
C1J03_RS12175	COG3257	ureidoglycine aminohydrolase activity
C1J03_RS12185	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C1J03_RS12190	COG0248	Ppx GppA phosphatase
C1J03_RS12205	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C1J03_RS12215	COG0745	RESPONSE REGULATOR receiver
C1J03_RS12225	COG0835	chemotaxis
C1J03_RS12230	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C1J03_RS12240	COG2201	protein-glutamate methylesterase activity
C1J03_RS12260	COG3246	L-lysine catabolic process to acetate
C1J03_RS12265	COG4177	L-phenylalanine transmembrane transporter activity
C1J03_RS12280	COG1137	ATPase activity
C1J03_RS12290	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1J03_RS12315	COG3485	protocatechuate 3,4-dioxygenase
C1J03_RS12330	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
C1J03_RS12330	COG1672	PFAM Archaeal ATPase
C1J03_RS12350	COG1696	Membrane protein involved in D-alanine export
C1J03_RS12360	COG0318	PFAM AMP-dependent synthetase and ligase
C1J03_RS12410	COG0166	Belongs to the GPI family
C1J03_RS12420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C1J03_RS12430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C1J03_RS12440	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C1J03_RS12445	COG1612	heme a metabolic process
C1J03_RS12455	COG0352	thiamine-phosphate diphosphorylase activity
C1J03_RS12475	COG2313	pseudouridylate synthase activity
C1J03_RS12490	COG0492	ferredoxin-NADP+ reductase activity
C1J03_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS12500	COG4166	transmembrane transport
C1J03_RS12510	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1J03_RS12535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C1J03_RS12540	COG2814	Major facilitator Superfamily
C1J03_RS12545	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C1J03_RS12575	COG2084	Dehydrogenase
C1J03_RS12580	COG2366	antibiotic biosynthetic process
C1J03_RS12595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C1J03_RS12600	COG1923	regulation of RNA biosynthetic process
C1J03_RS12610	COG0569	domain protein
C1J03_RS12625	COG2204	response regulator
C1J03_RS12630	COG5000	phosphorelay sensor kinase activity
C1J03_RS12635	COG2204	response regulator
C1J03_RS12640	COG3852	Histidine kinase
C1J03_RS12645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1J03_RS12650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C1J03_RS12650	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C1J03_RS12655	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C1J03_RS12660	COG1546	Belongs to the CinA family
C1J03_RS12660	COG1058	Belongs to the CinA family
C1J03_RS12665	COG2867	negative regulation of translational initiation
C1J03_RS12670	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C1J03_RS12680	COG2010	Cytochrome c
C1J03_RS12685	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C1J03_RS12695	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C1J03_RS12725	COG0697	spore germination
C1J03_RS12740	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C1J03_RS12745	COG0596	Alpha beta hydrolase
C1J03_RS12750	COG2326	polyphosphate kinase activity
C1J03_RS12755	COG1309	transcriptional regulator
C1J03_RS12770	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C1J03_RS12775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C1J03_RS12780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1J03_RS12795	COG1024	Enoyl-CoA hydratase
C1J03_RS12800	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C1J03_RS12805	COG2226	methyltransferase
C1J03_RS12810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C1J03_RS12820	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C1J03_RS12830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C1J03_RS12835	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C1J03_RS12840	COG0745	RESPONSE REGULATOR receiver
C1J03_RS12850	COG0482	sulfurtransferase activity
C1J03_RS12855	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1J03_RS12865	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1J03_RS12870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C1J03_RS12880	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1J03_RS12885	COG0750	zinc metalloprotease
C1J03_RS12890	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C1J03_RS12900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C1J03_RS12905	COG0233	cytoplasmic translational termination
C1J03_RS12915	COG0528	UMP kinase activity
C1J03_RS12920	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C1J03_RS12930	COG0601	transmembrane transport
C1J03_RS12935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1J03_RS12950	COG0741	lytic transglycosylase activity
C1J03_RS12955	COG0629	single-stranded DNA binding
C1J03_RS12965	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C1J03_RS12970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C1J03_RS12980	COG4974	Belongs to the 'phage' integrase family
C1J03_RS12990	COG4536	flavin adenine dinucleotide binding
C1J03_RS13045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1J03_RS13055	COG0022	dehydrogenase e1 component
C1J03_RS13065	COG1522	sequence-specific DNA binding
C1J03_RS13075	COG0028	Belongs to the TPP enzyme family
C1J03_RS13100	COG1129	ABC transporter
C1J03_RS13105	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS13120	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS13125	COG1879	ABC-type sugar transport system periplasmic component
C1J03_RS13140	COG4948	Mandelate Racemase Muconate Lactonizing
C1J03_RS13170	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C1J03_RS13180	COG0010	Belongs to the arginase family
C1J03_RS13190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1J03_RS13200	COG0542	response to heat
C1J03_RS13220	COG1764	response to oxidative stress
C1J03_RS13235	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C1J03_RS13250	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C1J03_RS13270	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C1J03_RS13275	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1J03_RS13285	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C1J03_RS13300	COG0840	transmembrane signaling receptor activity
C1J03_RS13305	COG0028	Belongs to the TPP enzyme family
C1J03_RS13310	COG0440	acetolactate synthase activity
C1J03_RS13335	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C1J03_RS13345	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C1J03_RS13350	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1J03_RS13355	COG0436	Aminotransferase
C1J03_RS13370	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C1J03_RS13380	COG0156	8-amino-7-oxononanoate synthase activity
C1J03_RS13455	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
C1J03_RS13475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1J03_RS13535	COG4191	Histidine kinase
C1J03_RS13570	COG0154	amidase activity
C1J03_RS13590	COG0406	alpha-ribazole phosphatase activity
C1J03_RS13595	COG0406	alpha-ribazole phosphatase activity
C1J03_RS13605	COG0776	regulation of translation
C1J03_RS13610	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C1J03_RS13620	COG3396	Phenylacetate-CoA oxygenase
C1J03_RS13625	COG3460	Phenylacetate-CoA oxygenase
C1J03_RS13630	COG3396	Phenylacetate-CoA oxygenase
C1J03_RS13635	COG2151	metal-sulfur cluster biosynthetic enzyme
C1J03_RS13640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1J03_RS13645	COG2030	dehydratase
C1J03_RS13645	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS13650	COG0343	queuine tRNA-ribosyltransferase activity
C1J03_RS13665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1J03_RS13670	COG0189	ligase activity
C1J03_RS13670	COG4067	protein conserved in archaea
C1J03_RS13675	COG2151	metal-sulfur cluster biosynthetic enzyme
C1J03_RS13700	COG0149	triose-phosphate isomerase activity
C1J03_RS13705	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1J03_RS13710	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1J03_RS13715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1J03_RS13720	COG2204	response regulator
C1J03_RS13730	COG2124	cytochrome p450
C1J03_RS13735	COG1522	sequence-specific DNA binding
C1J03_RS13740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C1J03_RS13740	COG1648	precorrin-2 dehydrogenase activity
C1J03_RS13750	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1J03_RS13755	COG0175	sulfate reduction
C1J03_RS13775	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C1J03_RS13800	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C1J03_RS13810	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C1J03_RS13830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C1J03_RS13835	COG2354	Protein conserved in bacteria
C1J03_RS13850	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C1J03_RS13875	COG1960	acyl-CoA dehydrogenase activity
C1J03_RS13895	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C1J03_RS13905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1J03_RS13920	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C1J03_RS13930	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C1J03_RS13935	COG2833	Protein of unknown function (DUF455)
C1J03_RS13940	COG0739	heme binding
C1J03_RS13955	COG0069	glutamate synthase activity
C1J03_RS13960	COG0471	metal ion transport
C1J03_RS13960	COG3273	potassium ion transport
C1J03_RS13975	COG0126	phosphoglycerate kinase activity
C1J03_RS13980	COG4221	oxidoreductase activity
C1J03_RS13985	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C1J03_RS13995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C1J03_RS14000	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1J03_RS14000	COG0022	dehydrogenase e1 component
C1J03_RS14005	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1J03_RS14090	COG4695	Portal protein
C1J03_RS14105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C1J03_RS14110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1J03_RS14125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C1J03_RS14140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C1J03_RS14145	COG3038	cytochrome b561
C1J03_RS14155	COG2353	YceI-like domain
C1J03_RS14165	COG0360	Binds together with S18 to 16S ribosomal RNA
C1J03_RS14170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C1J03_RS14175	COG0359	binds to the 23S rRNA
C1J03_RS14185	COG0737	Belongs to the 5'-nucleotidase family
C1J03_RS14190	COG0544	peptidyl-prolyl cis-trans isomerase activity
C1J03_RS14195	COG0427	acetyl-CoA hydrolase
C1J03_RS14200	COG2826	transposase and inactivated derivatives, IS30 family
C1J03_RS14215	COG3750	Belongs to the UPF0335 family
C1J03_RS14250	COG5002	protein histidine kinase activity
C1J03_RS14265	COG3800	Transcriptional regulator
C1J03_RS14265	COG1396	sequence-specific DNA binding
C1J03_RS14275	COG0559	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS14290	COG0410	ABC transporter
C1J03_RS14295	COG0511	ligase activity, forming carbon-carbon bonds
C1J03_RS14300	COG0439	Biotin carboxylase
C1J03_RS14305	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C1J03_RS14330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C1J03_RS14335	COG0740	serine-type endopeptidase activity
C1J03_RS14350	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C1J03_RS14365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1J03_RS14405	COG3483	tryptophan 2,3-dioxygenase activity
C1J03_RS14415	COG1960	acyl-CoA dehydrogenase activity
C1J03_RS14430	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS14475	COG3119	arylsulfatase activity
C1J03_RS14490	COG1566	PFAM secretion protein HlyD family protein
C1J03_RS14530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1J03_RS14545	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C1J03_RS14565	COG1752	Esterase of the alpha-beta hydrolase superfamily
C1J03_RS14575	COG3710	Transcriptional regulator
C1J03_RS14590	COG0517	IMP dehydrogenase activity
C1J03_RS14590	COG4175	Glycine betaine
C1J03_RS14600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1J03_RS14605	COG4311	Sarcosine oxidase, delta subunit
C1J03_RS14610	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1J03_RS14610	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1J03_RS14645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1J03_RS14650	COG0004	ammonium transporteR
C1J03_RS14655	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C1J03_RS14660	COG2218	PFAM glutamate synthase alpha subunit domain protein
C1J03_RS14665	COG0069	glutamate synthase activity
C1J03_RS14690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1J03_RS14720	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C1J03_RS14725	COG0668	transmembrane transport
C1J03_RS14735	COG0500	methyltransferase
C1J03_RS14740	COG1132	(ABC) transporter
C1J03_RS14750	COG2124	cytochrome p450
C1J03_RS14775	COG2003	Belongs to the UPF0758 family
C1J03_RS14780	COG4175	Glycine betaine
C1J03_RS14800	COG3842	ATPase activity
C1J03_RS14810	COG1175	transmembrane transport
C1J03_RS14880	COG0306	phosphate transporter
C1J03_RS14885	COG1234	tRNA 3'-trailer cleavage
C1J03_RS14915	COG3424	synthase
C1J03_RS14920	COG1755	Isoprenylcysteine carboxyl methyltransferase
C1J03_RS14935	COG2826	transposase and inactivated derivatives, IS30 family
C1J03_RS14955	COG1127	ABC transporter
C1J03_RS14960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C1J03_RS14975	COG1331	Highly conserved protein containing a thioredoxin domain
C1J03_RS14980	COG4235	cytochrome complex assembly
C1J03_RS14985	COG3088	subunit of a heme lyase
C1J03_RS14990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1J03_RS14995	COG1138	Cytochrome C-type biogenesis protein
C1J03_RS15000	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
C1J03_RS15010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1J03_RS15060	COG2391	methyltransferase activity
C1J03_RS15070	COG0156	8-amino-7-oxononanoate synthase activity
C1J03_RS15080	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1J03_RS15095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C1J03_RS15105	COG0737	Belongs to the 5'-nucleotidase family
C1J03_RS15110	COG3258	Cytochrome c
C1J03_RS15135	COG0785	Cytochrome C biogenesis protein
C1J03_RS15150	COG2391	methyltransferase activity
C1J03_RS15220	COG0006	proline dipeptidase activity
C1J03_RS15245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C1J03_RS15260	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1J03_RS15270	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C1J03_RS15275	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS15280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1J03_RS15290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1J03_RS15295	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1J03_RS15300	COG4133	protoheme IX ABC transporter activity
C1J03_RS15305	COG3737	Protein of unknown function (DUF498/DUF598)
C1J03_RS15315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1J03_RS15320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1J03_RS15325	COG1862	Preprotein translocase
C1J03_RS15335	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C1J03_RS15350	COG1160	GTP binding
C1J03_RS15400	COG3328	transposase activity
C1J03_RS15420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1J03_RS15455	COG0438	transferase activity, transferring glycosyl groups
C1J03_RS15455	COG0297	glycogen (starch) synthase activity
C1J03_RS15495	COG5265	(ABC) transporter
C1J03_RS15525	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1J03_RS15525	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1J03_RS15540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1J03_RS15555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C1J03_RS15575	COG0730	response to heat
C1J03_RS15580	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1J03_RS15620	COG0673	inositol 2-dehydrogenase activity
C1J03_RS15635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1J03_RS15640	COG3962	Belongs to the TPP enzyme family
C1J03_RS15645	COG0673	inositol 2-dehydrogenase activity
C1J03_RS15655	COG0673	inositol 2-dehydrogenase activity
C1J03_RS15660	COG1609	Transcriptional regulator
C1J03_RS15670	COG4214	carbohydrate transport
C1J03_RS15675	COG1129	ABC transporter
C1J03_RS15685	COG3718	enzyme involved in inositol metabolism
C1J03_RS15740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1J03_RS15750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C1J03_RS15760	COG0729	surface antigen
C1J03_RS15775	COG0583	DNA-binding transcription factor activity
C1J03_RS15780	COG2515	1-aminocyclopropane-1-carboxylate deaminase
C1J03_RS15795	COG4176	ABC-type proline glycine betaine transport system permease component
C1J03_RS15800	COG2267	carboxylic ester hydrolase activity
C1J03_RS15810	COG0604	alcohol dehydrogenase
C1J03_RS15820	COG2989	Protein conserved in bacteria
C1J03_RS15825	COG3228	Belongs to the MtfA family
C1J03_RS15870	COG2826	transposase and inactivated derivatives, IS30 family
C1J03_RS15875	COG0321	lipoyl(octanoyl) transferase activity
C1J03_RS15895	COG1610	YqeY-like protein
C1J03_RS15900	COG0505	Belongs to the CarA family
C1J03_RS15910	COG1802	Transcriptional regulator
C1J03_RS15930	COG1522	sequence-specific DNA binding
C1J03_RS15940	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C1J03_RS15950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1J03_RS15955	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C1J03_RS15960	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C1J03_RS15970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1J03_RS15970	COG0574	Belongs to the PEP-utilizing enzyme family
C1J03_RS15975	COG0751	glycine-tRNA ligase activity
C1J03_RS15985	COG0752	glycyl-tRNA synthetase alpha subunit
C1J03_RS16000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1J03_RS16010	COG1469	GTP cyclohydrolase I activity
C1J03_RS16025	COG0625	glutathione transferase activity
C1J03_RS16040	COG0552	protein localization to endoplasmic reticulum
C1J03_RS16045	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C1J03_RS16060	COG1570	exodeoxyribonuclease VII activity
C1J03_RS16065	COG0151	Belongs to the GarS family
C1J03_RS16085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1J03_RS16090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1J03_RS16095	COG0330	HflC and HflK could
C1J03_RS16100	COG0330	HflC and HflK could
C1J03_RS16110	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C1J03_RS16125	COG0625	glutathione transferase activity
C1J03_RS16130	COG1760	l-serine dehydratase
C1J03_RS16155	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C1J03_RS16190	COG0504	CTP synthase activity
C1J03_RS16195	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C1J03_RS16230	COG4215	(ABC) transporter
C1J03_RS16235	COG0765	amino acid transport
C1J03_RS16240	COG0174	glutamine synthetase
C1J03_RS16245	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C1J03_RS16245	COG0519	Catalyzes the synthesis of GMP from XMP
C1J03_RS16250	COG0174	glutamine synthetase
C1J03_RS16255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1J03_RS16270	COG3243	poly(R)-hydroxyalkanoic acid synthase
C1J03_RS16315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C1J03_RS16325	COG3220	belongs to the UPF0276 family
C1J03_RS16340	COG1393	Belongs to the ArsC family
C1J03_RS16355	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
C1J03_RS16385	COG1846	Transcriptional regulator
C1J03_RS16415	COG0534	Mate efflux family protein
C1J03_RS16435	COG0187	DNA topoisomerase II activity
C1J03_RS16455	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C1J03_RS16465	COG1136	(ABC) transporter
C1J03_RS16485	COG2133	pyrroloquinoline quinone binding
C1J03_RS16490	COG0442	prolyl-tRNA aminoacylation
C1J03_RS16495	COG0628	permease
C1J03_RS16505	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C1J03_RS16510	COG0248	Ppx GppA phosphatase
C1J03_RS16530	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C1J03_RS16545	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C1J03_RS16545	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C1J03_RS16560	COG4770	biotin carboxylase activity
C1J03_RS16590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C1J03_RS16600	COG3800	Transcriptional regulator
C1J03_RS16600	COG1396	sequence-specific DNA binding
C1J03_RS16625	COG3119	arylsulfatase activity
C1J03_RS16630	COG1309	transcriptional regulator
C1J03_RS16650	COG0217	transcriptional regulatory protein
C1J03_RS16655	COG0490	domain, Protein
C1J03_RS16655	COG0471	metal ion transport
C1J03_RS16660	COG3273	potassium ion transport
C1J03_RS16660	COG0471	metal ion transport
C1J03_RS16670	COG1692	metallophosphoesterase
C1J03_RS16675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C1J03_RS16680	COG2239	Acts as a magnesium transporter
C1J03_RS16685	COG0402	S-adenosylhomocysteine deaminase activity
C1J03_RS16700	COG0483	inositol monophosphate 1-phosphatase activity
C1J03_RS16705	COG1396	sequence-specific DNA binding
C1J03_RS16710	COG0583	DNA-binding transcription factor activity
C1J03_RS16715	COG0670	Belongs to the BI1 family
C1J03_RS16720	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C1J03_RS16725	COG0300	oxidoreductase activity
C1J03_RS16735	COG3023	N-Acetylmuramoyl-L-alanine amidase
C1J03_RS16745	COG0154	amidase activity
C1J03_RS16750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C1J03_RS16755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C1J03_RS16760	COG0590	tRNA wobble adenosine to inosine editing
C1J03_RS16765	COG1187	pseudouridine synthase activity
C1J03_RS16770	COG0861	Integral membrane protein TerC family
C1J03_RS16780	COG3853	Toxic anion resistance protein (TelA)
C1J03_RS16805	COG1490	D-aminoacyl-tRNA deacylase activity
C1J03_RS16825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1J03_RS16845	COG0657	acetylesterase activity
C1J03_RS16850	COG0318	PFAM AMP-dependent synthetase and ligase
C1J03_RS16855	COG1652	LysM domain
C1J03_RS16860	COG1132	(ABC) transporter
C1J03_RS16890	COG1960	acyl-CoA dehydrogenase activity
C1J03_RS16895	COG0583	DNA-binding transcription factor activity
C1J03_RS16930	COG1082	Xylose isomerase domain protein TIM barrel
C1J03_RS16930	COG3185	4-Hydroxyphenylpyruvate dioxygenase
C1J03_RS16935	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C1J03_RS16945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1J03_RS16955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1J03_RS16960	COG0673	inositol 2-dehydrogenase activity
C1J03_RS16975	COG1309	transcriptional regulator
C1J03_RS17020	COG0415	Belongs to the DNA photolyase family
C1J03_RS17040	COG0765	amino acid transport
C1J03_RS17070	COG2308	Evidence 4 Homologs of previously reported genes of
C1J03_RS17085	COG2826	transposase and inactivated derivatives, IS30 family
C1J03_RS17095	COG2826	transposase and inactivated derivatives, IS30 family
C1J03_RS17110	COG2358	TRAP transporter, solute receptor (TAXI family
C1J03_RS17140	COG1609	Transcriptional regulator
C1J03_RS17150	COG1175	transmembrane transport
C1J03_RS17155	COG0395	ABC-type sugar transport system, permease component
C1J03_RS17205	COG1401	restriction endodeoxyribonuclease activity
C1J03_RS17210	COG0514	ATP-dependent DNA helicase (RecQ)
C1J03_RS17240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1J03_RS17245	COG1121	(ABC) transporter
C1J03_RS17290	COG0523	cobalamin synthesis protein
C1J03_RS17295	COG0523	cobalamin synthesis protein
C1J03_RS17315	COG3845	ABC transporter
C1J03_RS17320	COG4603	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS17325	COG1079	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS17330	COG0402	S-adenosylhomocysteine deaminase activity
C1J03_RS17360	COG0604	alcohol dehydrogenase
C1J03_RS17365	COG0583	DNA-binding transcription factor activity
C1J03_RS17370	COG0583	DNA-binding transcription factor activity
C1J03_RS17375	COG0625	glutathione transferase activity
C1J03_RS17385	COG1942	4-Oxalocrotonate Tautomerase
C1J03_RS17390	COG2070	2-Nitropropane dioxygenase
C1J03_RS17415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1J03_RS17425	COG0246	Mannitol dehydrogenase
C1J03_RS17435	COG1802	Transcriptional regulator
C1J03_RS17440	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS17450	COG1129	ABC transporter
C1J03_RS17455	COG1063	alcohol dehydrogenase
C1J03_RS17460	COG2721	sulfolactate sulfo-lyase activity
C1J03_RS17470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1J03_RS17485	COG0069	glutamate synthase activity
C1J03_RS17490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C1J03_RS17490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C1J03_RS17520	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
C1J03_RS17530	COG0235	Class ii aldolase
C1J03_RS17535	COG3395	kinase activity
C1J03_RS17555	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1J03_RS17560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1J03_RS17565	COG0473	3-isopropylmalate dehydrogenase activity
C1J03_RS17575	COG2186	Transcriptional regulator
C1J03_RS17620	COG0326	Molecular chaperone. Has ATPase activity
C1J03_RS17625	COG0667	Aldo Keto reductase
C1J03_RS17670	COG5598	trimethylamine methyltransferase
C1J03_RS17680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C1J03_RS17690	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C1J03_RS17720	COG4336	lyase activity
C1J03_RS17725	COG0583	DNA-binding transcription factor activity
C1J03_RS17770	COG2267	carboxylic ester hydrolase activity
C1J03_RS17780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1J03_RS17785	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS17790	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS17815	COG0789	Transcriptional regulator
C1J03_RS17835	COG3119	arylsulfatase activity
C1J03_RS17840	COG0435	Glutathione S-transferase
C1J03_RS17865	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C1J03_RS17870	COG1530	ribonuclease E activity
C1J03_RS17875	COG0424	maF-like protein
C1J03_RS17880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C1J03_RS17885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1J03_RS17890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C1J03_RS17900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C1J03_RS17905	COG1703	isobutyryl-CoA mutase activity
C1J03_RS17910	COG1643	Atp-dependent helicase
C1J03_RS17925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C1J03_RS17940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C1J03_RS17955	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
C1J03_RS17960	COG2943	transferase activity, transferring hexosyl groups
C1J03_RS17970	COG2877	3-deoxy-8-phosphooctulonate synthase activity
C1J03_RS18005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C1J03_RS18020	COG1272	protein, Hemolysin III
C1J03_RS18050	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C1J03_RS18055	COG1214	PFAM Peptidase M22, glycoprotease
C1J03_RS18065	COG1744	ABC transporter substrate-binding protein PnrA-like
C1J03_RS18070	COG3845	ABC transporter
C1J03_RS18075	COG4603	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS18080	COG1079	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS18085	COG0730	response to heat
C1J03_RS18095	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS18100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C1J03_RS18120	COG0604	alcohol dehydrogenase
C1J03_RS18125	COG2937	Belongs to the GPAT DAPAT family
C1J03_RS18130	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C1J03_RS18130	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C1J03_RS18140	COG0813	purine-nucleoside phosphorylase activity
C1J03_RS18200	COG0039	L-malate dehydrogenase activity
C1J03_RS18215	COG2301	Belongs to the HpcH HpaI aldolase family
C1J03_RS18230	COG2030	dehydratase
C1J03_RS18240	COG0045	succinate-CoA ligase (ADP-forming) activity
C1J03_RS18260	COG0567	Dehydrogenase, E1 component
C1J03_RS18265	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1J03_RS18300	COG2884	Cell division ATP-binding protein ftsE
C1J03_RS18315	COG0019	diaminopimelate decarboxylase activity
C1J03_RS18325	COG0165	Argininosuccinate lyase
C1J03_RS18330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1J03_RS18350	COG0800	Aldolase
C1J03_RS18355	COG0129	dihydroxy-acid dehydratase activity
C1J03_RS18365	COG0318	PFAM AMP-dependent synthetase and ligase
C1J03_RS18370	COG0572	uridine kinase
C1J03_RS18395	COG1940	carbohydrate kinase activity
C1J03_RS18395	COG1846	Transcriptional regulator
C1J03_RS18405	COG0028	Belongs to the TPP enzyme family
C1J03_RS18420	COG1011	Hydrolase
C1J03_RS18430	COG3639	organic phosphonate transmembrane transporter activity
C1J03_RS18435	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C1J03_RS18445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1J03_RS18455	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C1J03_RS18465	COG0124	histidyl-tRNA synthetase
C1J03_RS18490	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C1J03_RS18500	COG3845	ABC transporter
C1J03_RS18505	COG4603	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS18515	COG1079	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS18565	COG0277	FAD linked oxidase domain protein
C1J03_RS18650	COG0653	protein targeting
C1J03_RS18675	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS18690	COG0747	negative chemotaxis
C1J03_RS18695	COG0601	transmembrane transport
C1J03_RS18700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1J03_RS18705	COG0444	Belongs to the ABC transporter superfamily
C1J03_RS18710	COG4608	Belongs to the ABC transporter superfamily
C1J03_RS18820	COG2826	transposase and inactivated derivatives, IS30 family
C1J03_RS18830	COG0701	Predicted permease
C1J03_RS18840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1J03_RS18840	COG3453	Protein conserved in bacteria
C1J03_RS18880	COG4974	Belongs to the 'phage' integrase family
C1J03_RS18885	COG0517	IMP dehydrogenase activity
C1J03_RS18890	COG0583	DNA-binding transcription factor activity
C1J03_RS18895	COG2226	methyltransferase
C1J03_RS18965	COG0435	Glutathione S-transferase
C1J03_RS18990	COG2259	Doxx family
C1J03_RS19020	COG2207	Transcriptional regulator
C1J03_RS19040	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
C1J03_RS19060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1J03_RS19095	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C1J03_RS19105	COG2226	methyltransferase
C1J03_RS19220	COG2197	response regulator
C1J03_RS19235	COG0583	DNA-binding transcription factor activity
C1J03_RS19240	COG0154	amidase activity
C1J03_RS19245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1J03_RS19250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1J03_RS19260	COG0277	FAD linked oxidase domain protein
C1J03_RS19315	COG1162	GTPase activity
C1J03_RS19345	COG3842	ATPase activity
C1J03_RS19355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1J03_RS19365	COG0738	Major facilitator superfamily
C1J03_RS19380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1J03_RS19385	COG0006	proline dipeptidase activity
C1J03_RS19390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1J03_RS19415	COG0688	phosphatidylethanolamine metabolic process
C1J03_RS19430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1J03_RS19435	COG1858	cytochrome C peroxidase
C1J03_RS19445	COG1940	carbohydrate kinase activity
C1J03_RS19450	COG4213	ABC transporter substrate-binding protein
C1J03_RS19455	COG4214	carbohydrate transport
C1J03_RS19460	COG1129	ABC transporter
C1J03_RS19465	COG1070	Carbohydrate kinase
C1J03_RS19485	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C1J03_RS19490	COG0830	nickel cation binding
C1J03_RS19495	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
C1J03_RS19500	COG0804	urea catabolic process
C1J03_RS19505	COG0832	Belongs to the urease beta subunit family
C1J03_RS19510	COG0831	urea catabolic process
C1J03_RS19515	COG0829	nickel cation binding
C1J03_RS19520	COG0837	glucose binding
C1J03_RS19540	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C1J03_RS19545	COG0363	glucosamine-6-phosphate deaminase activity
C1J03_RS19555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1J03_RS19570	COG0673	inositol 2-dehydrogenase activity
C1J03_RS19575	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C1J03_RS19585	COG1218	3'(2'),5'-bisphosphate nucleotidase
C1J03_RS19635	COG1442	glycosyl transferase family 8
C1J03_RS19635	COG1216	Glycosyl transferase, family 2
C1J03_RS19680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1J03_RS19690	COG0318	PFAM AMP-dependent synthetase and ligase
C1J03_RS19700	COG1024	Enoyl-CoA hydratase
C1J03_RS19710	COG1960	acyl-CoA dehydrogenase activity
C1J03_RS19715	COG1960	acyl-CoA dehydrogenase activity
C1J03_RS19720	COG0183	Belongs to the thiolase family
C1J03_RS19725	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1J03_RS19725	COG1024	Enoyl-CoA hydratase
C1J03_RS19760	COG0747	negative chemotaxis
C1J03_RS19765	COG0601	transmembrane transport
C1J03_RS19770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1J03_RS19775	COG0668	transmembrane transport
C1J03_RS19785	COG0438	transferase activity, transferring glycosyl groups
C1J03_RS19795	COG0588	phosphoglycerate mutase activity
C1J03_RS19815	COG2824	Alkylphosphonate utilization operon protein PhnA
C1J03_RS19830	COG0481	GTPase activity
C1J03_RS19855	COG5328	Belongs to the UPF0262 family
C1J03_RS19860	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1J03_RS19875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C1J03_RS19890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1J03_RS19900	COG2226	methyltransferase
C1J03_RS19905	COG2095	MarC family integral membrane protein
C1J03_RS19910	COG0730	response to heat
C1J03_RS19920	COG0583	DNA-binding transcription factor activity
C1J03_RS19925	COG2095	MarC family integral membrane protein
C1J03_RS19935	COG1309	transcriptional regulator
C1J03_RS19955	COG2951	lytic endotransglycosylase activity
C1J03_RS19960	COG1024	Enoyl-CoA hydratase
C1J03_RS19970	COG1022	Amp-dependent synthetase and ligase
C1J03_RS19970	COG3320	Male sterility
C1J03_RS19980	COG0582	viral genome integration into host DNA
C1J03_RS20010	COG4974	Belongs to the 'phage' integrase family
C1J03_RS20020	COG1902	pentaerythritol trinitrate reductase activity
C1J03_RS20020	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1J03_RS20040	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C1J03_RS20060	COG0556	nucleotide-excision repair
C1J03_RS20080	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
C1J03_RS20100	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C1J03_RS20105	COG1115	amino acid carrier protein
C1J03_RS20135	COG0488	(ABC) transporter
C1J03_RS20145	COG1278	Cold shock
C1J03_RS20160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1J03_RS20165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1J03_RS20170	COG1116	anion transmembrane transporter activity
C1J03_RS20190	COG1309	transcriptional regulator
C1J03_RS20205	COG5507	3-demethylubiquinone-9 3-methyltransferase
C1J03_RS20235	COG0509	glycine decarboxylation via glycine cleavage system
C1J03_RS20245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C1J03_RS20290	COG3046	protein related to deoxyribodipyrimidine photolyase
C1J03_RS20305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C1J03_RS20335	COG0768	penicillin binding
C1J03_RS20340	COG0772	Belongs to the SEDS family
C1J03_RS20350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1J03_RS20355	COG0339	signal peptide processing
C1J03_RS20360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C1J03_RS20365	COG0756	dUTP diphosphatase activity
C1J03_RS20370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C1J03_RS20395	COG0606	chelatase, subunit chli
C1J03_RS20405	COG0189	ligase activity
C1J03_RS20410	COG0792	nuclease activity
C1J03_RS20415	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C1J03_RS20425	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C1J03_RS20435	COG0728	peptidoglycan biosynthetic process
C1J03_RS20445	COG0180	Tryptophanyl-tRNA synthetase
C1J03_RS20450	COG1335	isochorismatase
C1J03_RS20460	COG0778	Nitroreductase
C1J03_RS20475	COG0346	lactoylglutathione lyase activity
C1J03_RS20480	COG0745	RESPONSE REGULATOR receiver
C1J03_RS20505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C1J03_RS20515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C1J03_RS20525	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C1J03_RS20535	COG0110	maltose O-acetyltransferase activity
C1J03_RS20580	COG2132	Multicopper oxidase
C1J03_RS20590	COG0786	glutamate:sodium symporter activity
C1J03_RS20595	COG1802	Transcriptional regulator
C1J03_RS20600	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS20610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1J03_RS20630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1J03_RS20645	COG0246	Mannitol dehydrogenase
C1J03_RS20650	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS20660	COG1904	glucuronate isomerase
C1J03_RS20670	COG1802	Transcriptional regulator
C1J03_RS20685	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1J03_RS20685	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1J03_RS20690	COG1312	Catalyzes the dehydration of D-mannonate
C1J03_RS20710	COG0583	DNA-binding transcription factor activity
C1J03_RS20715	COG0318	PFAM AMP-dependent synthetase and ligase
C1J03_RS20765	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
C1J03_RS20775	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C1J03_RS20785	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C1J03_RS20800	COG0284	orotidine-5'-phosphate decarboxylase activity
C1J03_RS20810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C1J03_RS20825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C1J03_RS20835	COG1840	ABC-type Fe3 transport system, periplasmic component
C1J03_RS20840	COG0625	glutathione transferase activity
C1J03_RS20850	COG1178	ABC-type Fe3 transport system permease component
C1J03_RS20855	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C1J03_RS20880	COG0559	Belongs to the binding-protein-dependent transport system permease family
C1J03_RS20900	COG4191	Histidine kinase
C1J03_RS20920	COG3383	formate dehydrogenase (NAD+) activity
C1J03_RS20930	COG0625	glutathione transferase activity
C1J03_RS20965	COG1595	DNA-templated transcription, initiation
C1J03_RS20970	COG3806	Anti-sigma factor
C1J03_RS20990	COG2351	hydroxyisourate hydrolase activity
C1J03_RS20995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1J03_RS21000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1J03_RS21000	COG1321	iron dependent repressor
C1J03_RS21005	COG1121	(ABC) transporter
C1J03_RS21010	COG0803	Belongs to the bacterial solute-binding protein 9 family
C1J03_RS21015	COG2205	protein histidine kinase activity
C1J03_RS21020	COG0745	RESPONSE REGULATOR receiver
C1J03_RS21035	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS21040	COG0612	Peptidase, M16
C1J03_RS21045	COG0612	Peptidase, M16
C1J03_RS21060	COG0138	bifunctional purine biosynthesis protein purh
C1J03_RS21090	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C1J03_RS21095	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C1J03_RS21105	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C1J03_RS21125	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C1J03_RS21155	COG3239	Fatty acid desaturase
C1J03_RS21160	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
C1J03_RS21175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1J03_RS21180	COG0028	Belongs to the TPP enzyme family
C1J03_RS21190	COG0243	molybdopterin cofactor binding
C1J03_RS21195	COG0437	4 iron, 4 sulfur cluster binding
C1J03_RS21205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C1J03_RS21210	COG0741	lytic transglycosylase activity
C1J03_RS21220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1J03_RS21220	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C1J03_RS21230	COG0431	NADPH-dependent FMN reductase
C1J03_RS21240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C1J03_RS21240	COG2169	Transcriptional regulator
C1J03_RS21245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C1J03_RS21250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1J03_RS21265	COG1051	belongs to the nudix hydrolase family
C1J03_RS21275	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1J03_RS21275	COG1902	pentaerythritol trinitrate reductase activity
C1J03_RS21280	COG0583	DNA-binding transcription factor activity
C1J03_RS21300	COG1546	Belongs to the CinA family
C1J03_RS21300	COG1058	Belongs to the CinA family
C1J03_RS21305	COG1489	DNA binding
C1J03_RS21310	COG0024	Methionine aminopeptidase
C1J03_RS21315	COG0742	ribosomal rna small subunit methyltransferase
C1J03_RS21325	COG0678	peroxiredoxin activity
C1J03_RS21330	COG0668	transmembrane transport
C1J03_RS21335	COG2154	pterin-4-alpha-carbinolamine dehydratase
C1J03_RS21355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1J03_RS21365	COG0384	phenazine biosynthesis protein PhzF
C1J03_RS21380	COG0004	ammonium transporteR
C1J03_RS21390	COG2897	thiosulfate sulfurtransferase activity
C1J03_RS21400	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C1J03_RS21410	COG3008	intermembrane lipid transfer
C1J03_RS21410	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C1J03_RS21415	COG2995	paraquat-inducible protein a
C1J03_RS21470	COG4191	Histidine kinase
C1J03_RS21495	COG2175	clavaminate synthase activity
C1J03_RS21500	COG0583	DNA-binding transcription factor activity
C1J03_RS21520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1J03_RS21525	COG1396	sequence-specific DNA binding
C1J03_RS21530	COG1295	ribonuclease BN
C1J03_RS21535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1J03_RS21545	COG0747	negative chemotaxis
C1J03_RS21560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1J03_RS21570	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS21575	COG3191	aminopeptidase activity
C1J03_RS21655	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS21675	COG3591	Belongs to the peptidase S1B family
C1J03_RS21685	COG0247	lactate metabolic process
C1J03_RS21695	COG0277	FAD linked oxidase domain protein
C1J03_RS21700	COG0277	FAD linked oxidase domain protein
C1J03_RS21715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C1J03_RS21720	COG0799	negative regulation of ribosome biogenesis
C1J03_RS21730	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C1J03_RS21730	COG3264	Mechanosensitive ion channel
C1J03_RS21740	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C1J03_RS21760	COG0066	3-isopropylmalate dehydratase activity
C1J03_RS21775	COG0473	3-isopropylmalate dehydrogenase activity
C1J03_RS21785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C1J03_RS21835	COG1609	Transcriptional regulator
C1J03_RS21840	COG3214	Protein conserved in bacteria
C1J03_RS21845	COG1414	Transcriptional regulator
C1J03_RS21870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1J03_RS21875	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C1J03_RS21885	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1J03_RS21885	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1J03_RS21895	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C1J03_RS21900	COG1984	allophanate hydrolase subunit 2
C1J03_RS21905	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C1J03_RS21910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C1J03_RS21920	COG3246	L-lysine catabolic process to acetate
C1J03_RS21925	COG3485	protocatechuate 3,4-dioxygenase
C1J03_RS21930	COG3485	protocatechuate 3,4-dioxygenase
C1J03_RS21935	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C1J03_RS21955	COG1368	sulfuric ester hydrolase activity
C1J03_RS21990	COG2808	Putative FMN-binding domain
C1J03_RS22000	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C1J03_RS22005	COG1178	ABC-type Fe3 transport system permease component
C1J03_RS22010	COG4143	(ABC) transporter
C1J03_RS22015	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C1J03_RS22030	COG0697	spore germination
C1J03_RS22050	COG2378	regulation of single-species biofilm formation
C1J03_RS22055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C1J03_RS22060	COG1846	Transcriptional regulator
C1J03_RS22065	COG0745	RESPONSE REGULATOR receiver
C1J03_RS22070	COG1722	exodeoxyribonuclease VII activity
C1J03_RS22075	COG0142	geranyltranstransferase activity
C1J03_RS22080	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C1J03_RS22105	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1J03_RS22125	COG1596	polysaccharide export
C1J03_RS22130	COG0438	transferase activity, transferring glycosyl groups
C1J03_RS22140	COG0045	succinate-CoA ligase (ADP-forming) activity
C1J03_RS22145	COG1960	acyl-CoA dehydrogenase activity
C1J03_RS22155	COG0583	DNA-binding transcription factor activity
C1J03_RS22165	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C1J03_RS22170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C1J03_RS22195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1J03_RS22200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1J03_RS22210	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C1J03_RS22220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1J03_RS22245	COG1231	oxidoreductase activity
C1J03_RS22255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C1J03_RS22270	COG1846	Transcriptional regulator
C1J03_RS22280	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
C1J03_RS22290	COG0747	negative chemotaxis
C1J03_RS22295	COG0601	transmembrane transport
C1J03_RS22300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1J03_RS22305	COG0444	Belongs to the ABC transporter superfamily
C1J03_RS22320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C1J03_RS22325	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1J03_RS22330	COG0297	glycogen (starch) synthase activity
C1J03_RS22340	COG0033	Phosphoglucomutase
C1J03_RS22345	COG0058	SHG alpha-glucan phosphorylase activity
C1J03_RS22355	COG2814	Major facilitator Superfamily
C1J03_RS22365	COG0366	Alpha amylase catalytic
C1J03_RS22370	COG1280	lysine exporter protein (LysE YggA)
C1J03_RS22400	COG0318	PFAM AMP-dependent synthetase and ligase
C1J03_RS22410	COG1696	Membrane protein involved in D-alanine export
C1J03_RS22435	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C1J03_RS22440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C1J03_RS22465	COG0702	epimerase
C1J03_RS22515	COG0583	DNA-binding transcription factor activity
C1J03_RS22525	COG2375	cellular response to nickel ion
C1J03_RS22530	COG3618	amidohydrolase
C1J03_RS22535	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1J03_RS22540	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS22545	COG2721	sulfolactate sulfo-lyase activity
C1J03_RS22550	COG2721	sulfolactate sulfo-lyase activity
C1J03_RS22555	COG4948	Mandelate Racemase Muconate Lactonizing
C1J03_RS22560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C1J03_RS22565	COG3254	rhamnose metabolic process
C1J03_RS22575	COG3842	ATPase activity
C1J03_RS22580	COG0395	ABC-type sugar transport system, permease component
C1J03_RS22585	COG1175	transmembrane transport
C1J03_RS22595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C1J03_RS22620	COG1414	Transcriptional regulator
C1J03_RS22630	COG1560	Kdo2-lipid A biosynthetic process
C1J03_RS22665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1J03_RS22670	COG0436	Aminotransferase
C1J03_RS22685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C1J03_RS22685	COG2111	Na H antiporter
C1J03_RS22690	COG1006	Multisubunit Na H antiporter MnhC subunit
C1J03_RS22695	COG0651	ATP synthesis coupled electron transport
C1J03_RS22700	COG1863	multisubunit Na H antiporter MnhE subunit
C1J03_RS22705	COG2212	antiporter activity
C1J03_RS22710	COG1320	monovalent cation:proton antiporter activity
C1J03_RS22720	COG2378	regulation of single-species biofilm formation
C1J03_RS22740	COG3842	ATPase activity
C1J03_RS22755	COG1177	transmembrane transport
C1J03_RS22760	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS22765	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS22770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1J03_RS22785	COG1840	ABC-type Fe3 transport system, periplasmic component
C1J03_RS22795	COG4191	Histidine kinase
C1J03_RS22795	COG0784	Response regulator, receiver
C1J03_RS22805	COG0583	DNA-binding transcription factor activity
C1J03_RS22815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1J03_RS22825	COG0673	inositol 2-dehydrogenase activity
C1J03_RS22830	COG1609	Transcriptional regulator
C1J03_RS22850	COG3842	ATPase activity
C1J03_RS22860	COG0395	ABC-type sugar transport system, permease component
C1J03_RS22865	COG1175	transmembrane transport
C1J03_RS22870	COG1653	transport
C1J03_RS22875	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS22880	COG1024	Enoyl-CoA hydratase
C1J03_RS22890	COG0346	lactoylglutathione lyase activity
C1J03_RS22905	COG2010	Cytochrome c
C1J03_RS22930	COG1338	Plays a role in the flagellum-specific transport system
C1J03_RS22935	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1J03_RS22945	COG1766	The M ring may be actively involved in energy transduction
C1J03_RS22950	COG4786	Flagellar basal body rod
C1J03_RS22955	COG1987	bacterial-type flagellum assembly
C1J03_RS22960	COG1677	Flagellar hook-basal body complex protein FliE
C1J03_RS22965	COG1558	bacterial-type flagellum-dependent cell motility
C1J03_RS22985	COG5443	negative regulation of bacterial-type flagellum assembly
C1J03_RS22995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1J03_RS23015	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C1J03_RS23020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1J03_RS23025	COG1177	transmembrane transport
C1J03_RS23030	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1J03_RS23035	COG3842	ATPase activity
C1J03_RS23055	COG3842	ATPase activity
C1J03_RS23065	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1J03_RS23075	COG2951	lytic endotransglycosylase activity
C1J03_RS23090	COG0557	exoribonuclease II activity
C1J03_RS23105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1J03_RS23135	COG2171	N-acyltransferase activity
C1J03_RS23155	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C1J03_RS23170	COG0560	Phosphoserine phosphatase
C1J03_RS23170	COG3830	Belongs to the UPF0237 family
C1J03_RS23175	COG2197	response regulator
C1J03_RS23190	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C1J03_RS23190	COG0662	Cupin 2, conserved barrel domain protein
C1J03_RS23205	COG0784	Response regulator, receiver
C1J03_RS23205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1J03_RS23205	COG2198	Histidine kinase
C1J03_RS23205	COG2205	protein histidine kinase activity
C1J03_RS23240	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C1J03_RS23245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1J03_RS23250	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C1J03_RS23260	COG1063	alcohol dehydrogenase
C1J03_RS23265	COG0156	8-amino-7-oxononanoate synthase activity
C1J03_RS23270	COG1396	sequence-specific DNA binding
C1J03_RS23275	COG0183	Belongs to the thiolase family
C1J03_RS23285	COG2226	methyltransferase
C1J03_RS23290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C1J03_RS23295	COG1024	Enoyl-CoA hydratase
C1J03_RS23300	COG0268	Binds directly to 16S ribosomal RNA
C1J03_RS23305	COG1192	Involved in chromosome partitioning
C1J03_RS23310	COG1475	DNA binding
C1J03_RS23365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C1J03_RS23520	COG0010	Belongs to the arginase family
C1J03_RS23570	COG0628	permease
C1J03_RS23585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1J03_RS23595	COG1053	succinate dehydrogenase
C1J03_RS23595	COG3976	FMN-binding domain protein
C1J03_RS23595	COG0431	NADPH-dependent FMN reductase
C1J03_RS23625	COG2188	Transcriptional regulator
C1J03_RS23630	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C1J03_RS23635	COG0066	3-isopropylmalate dehydratase activity
C1J03_RS23640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1J03_RS23715	COG0523	cobalamin synthesis protein
C1J03_RS23760	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1J03_RS23825	COG1067	ATP-dependent peptidase activity
C1J03_RS23835	COG3118	belongs to the thioredoxin family
C1J03_RS23840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C1J03_RS23855	COG0747	negative chemotaxis
C1J03_RS23860	COG0601	transmembrane transport
C1J03_RS23865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1J03_RS23900	COG2116	formate transmembrane transporter activity
C1J03_RS23935	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C1J03_RS23940	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C1J03_RS23945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C1J03_RS23970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C1J03_RS23975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C1J03_RS23985	COG3243	poly(R)-hydroxyalkanoic acid synthase
C1J03_RS23990	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C1J03_RS24015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1J03_RS24020	COG0022	dehydrogenase e1 component
C1J03_RS24020	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1J03_RS24040	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C1J03_RS24065	COG0701	Predicted permease
C1J03_RS24105	COG0577	efflux transmembrane transporter activity
C1J03_RS24105	COG1136	(ABC) transporter
C1J03_RS24115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1J03_RS24120	COG0842	Transport permease protein
C1J03_RS24120	COG1129	ABC transporter
C1J03_RS24125	COG0842	Transport permease protein
C1J03_RS24170	COG0530	calcium, potassium:sodium antiporter activity
C1J03_RS24195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1J03_RS24195	COG0551	DNA topoisomerase type I activity
C1J03_RS24280	COG0243	molybdopterin cofactor binding
C1J03_RS24290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1J03_RS24295	COG0235	Class ii aldolase
C1J03_RS24310	COG4948	Mandelate Racemase Muconate Lactonizing
C1J03_RS24325	COG4176	ABC-type proline glycine betaine transport system permease component
C1J03_RS24340	COG4948	Mandelate Racemase Muconate Lactonizing
C1J03_RS24345	COG1522	sequence-specific DNA binding
C1J03_RS24350	COG0183	Belongs to the thiolase family
C1J03_RS24355	COG1960	acyl-CoA dehydrogenase activity
C1J03_RS24390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C1J03_RS24415	COG3119	arylsulfatase activity
C1J03_RS24460	COG3119	arylsulfatase activity
C1J03_RS24465	COG1304	FMN binding
C1J03_RS24475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C1J03_RS24490	COG1414	Transcriptional regulator
C1J03_RS24495	COG3246	L-lysine catabolic process to acetate
C1J03_RS24500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1J03_RS24515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C1J03_RS24530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1J03_RS24535	COG1028	Short-chain dehydrogenase reductase Sdr
C1J03_RS24540	COG1448	Aminotransferase
C1J03_RS24560	COG3119	arylsulfatase activity
C1J03_RS24565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1J03_RS24590	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C1J03_RS24600	COG1213	nucleotidyl transferase
C1J03_RS24610	COG0459	protein refolding
C1J03_RS24615	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C1J03_RS24620	COG3128	pkhd-type hydroxylase
C1J03_RS24625	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C1J03_RS24675	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C1J03_RS24685	COG3177	Filamentation induced by cAMP protein fic
C1J03_RS24715	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C1J03_RS24720	COG1192	Involved in chromosome partitioning
C1J03_RS24725	COG1475	DNA binding
C1J03_RS24730	COG1414	Transcriptional regulator
C1J03_RS24750	COG3505	Type IV secretory pathway VirD4
C1J03_RS24775	COG1175	transmembrane transport
C1J03_RS24780	COG0395	ABC-type sugar transport system, permease component
C1J03_RS24805	COG0800	Aldolase
C1J03_RS24810	COG3734	2-keto-3-deoxy-galactonokinase
C1J03_RS24815	COG4948	Mandelate Racemase Muconate Lactonizing
C1J03_RS24820	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS24835	COG4214	carbohydrate transport
C1J03_RS24845	COG1879	ABC-type sugar transport system periplasmic component
C1J03_RS24850	COG2186	Transcriptional regulator
C1J03_RS24855	COG0739	heme binding
C1J03_RS24855	COG0741	lytic transglycosylase activity
C1J03_RS24855	COG1196	nuclear chromosome segregation
C1J03_RS24885	COG1012	belongs to the aldehyde dehydrogenase family
C1J03_RS24890	COG4638	Rieske (2fe-2S)
C1J03_RS24905	COG0604	alcohol dehydrogenase
C1J03_RS24910	COG4948	Mandelate Racemase Muconate Lactonizing
C1J03_RS24915	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C1J03_RS24925	COG1234	tRNA 3'-trailer cleavage
C1J03_RS24930	COG3119	arylsulfatase activity
C1J03_RS24960	COG0277	FAD linked oxidase domain protein
C1J03_RS24985	COG2267	carboxylic ester hydrolase activity
C1J03_RS24990	COG2378	regulation of single-species biofilm formation
C1J03_RS25010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1J03_RS25020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1J03_RS25035	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C1J03_RS25115	COG2866	Carboxypeptidase
C1J03_RS25130	COG3842	ATPase activity
C1J03_RS25155	COG0028	Belongs to the TPP enzyme family