locus-tag	class	description
FIU94_RS00035	COG0640	Transcriptional regulator
FIU94_RS00055	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIU94_RS00065	COG3220	belongs to the UPF0276 family
FIU94_RS00080	COG1393	Belongs to the ArsC family
FIU94_RS00085	COG1278	Cold shock
FIU94_RS00105	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FIU94_RS00120	COG0346	lactoylglutathione lyase activity
FIU94_RS00135	COG1846	Transcriptional regulator
FIU94_RS00165	COG0534	Mate efflux family protein
FIU94_RS00185	COG0596	Alpha beta hydrolase
FIU94_RS00190	COG0662	Cupin 2, conserved barrel domain protein
FIU94_RS00195	COG0187	DNA topoisomerase II activity
FIU94_RS00220	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FIU94_RS00225	COG1136	(ABC) transporter
FIU94_RS00240	COG0442	prolyl-tRNA aminoacylation
FIU94_RS00250	COG2195	Cleaves the N-terminal amino acid of tripeptides
FIU94_RS00280	COG0628	permease
FIU94_RS00290	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FIU94_RS00310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FIU94_RS00325	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU94_RS00325	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU94_RS00345	COG4770	biotin carboxylase activity
FIU94_RS00370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU94_RS00375	COG2814	Major facilitator Superfamily
FIU94_RS00380	COG3800	Transcriptional regulator
FIU94_RS00380	COG1396	sequence-specific DNA binding
FIU94_RS00395	COG1012	belongs to the aldehyde dehydrogenase family
FIU94_RS00400	COG3119	arylsulfatase activity
FIU94_RS00405	COG1309	transcriptional regulator
FIU94_RS00430	COG0217	transcriptional regulatory protein
FIU94_RS00435	COG3273	potassium ion transport
FIU94_RS00435	COG0471	metal ion transport
FIU94_RS00450	COG3273	potassium ion transport
FIU94_RS00450	COG0471	metal ion transport
FIU94_RS00455	COG1692	metallophosphoesterase
FIU94_RS00465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FIU94_RS00470	COG2239	Acts as a magnesium transporter
FIU94_RS00475	COG0402	S-adenosylhomocysteine deaminase activity
FIU94_RS00485	COG0483	inositol monophosphate 1-phosphatase activity
FIU94_RS00490	COG1396	sequence-specific DNA binding
FIU94_RS00495	COG0583	DNA-binding transcription factor activity
FIU94_RS00505	COG0670	Belongs to the BI1 family
FIU94_RS00510	COG3813	Protein conserved in bacteria
FIU94_RS00520	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FIU94_RS00530	COG3023	N-Acetylmuramoyl-L-alanine amidase
FIU94_RS00540	COG0154	amidase activity
FIU94_RS00545	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIU94_RS00565	COG0590	tRNA wobble adenosine to inosine editing
FIU94_RS00575	COG0861	Integral membrane protein TerC family
FIU94_RS00590	COG3853	Toxic anion resistance protein (TelA)
FIU94_RS00620	COG1490	D-aminoacyl-tRNA deacylase activity
FIU94_RS00630	COG0747	negative chemotaxis
FIU94_RS00635	COG0601	transmembrane transport
FIU94_RS00640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU94_RS00645	COG4172	Belongs to the ABC transporter superfamily
FIU94_RS00655	COG0657	acetylesterase activity
FIU94_RS00660	COG0318	PFAM AMP-dependent synthetase and ligase
FIU94_RS00665	COG1132	(ABC) transporter
FIU94_RS00685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIU94_RS00700	COG1522	sequence-specific DNA binding
FIU94_RS00715	COG1070	Carbohydrate kinase
FIU94_RS00720	COG1129	ABC transporter
FIU94_RS00725	COG4214	carbohydrate transport
FIU94_RS00730	COG4213	ABC transporter substrate-binding protein
FIU94_RS00735	COG1940	carbohydrate kinase activity
FIU94_RS00745	COG1858	cytochrome C peroxidase
FIU94_RS00750	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FIU94_RS00760	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FIU94_RS00770	COG0366	Alpha amylase catalytic
FIU94_RS00780	COG1228	amidohydrolase
FIU94_RS00785	COG0583	DNA-binding transcription factor activity
FIU94_RS00790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU94_RS00800	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU94_RS00800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU94_RS00805	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FIU94_RS00815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FIU94_RS00820	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FIU94_RS00825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FIU94_RS00830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FIU94_RS00835	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIU94_RS00840	COG1253	flavin adenine dinucleotide binding
FIU94_RS00845	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FIU94_RS00850	COG1702	phosphate starvation-inducible protein PhoH
FIU94_RS00865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIU94_RS00880	COG0735	belongs to the Fur family
FIU94_RS00890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIU94_RS00900	COG1012	belongs to the aldehyde dehydrogenase family
FIU94_RS00905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIU94_RS00910	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIU94_RS00925	COG1047	Peptidyl-prolyl cis-trans
FIU94_RS00950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FIU94_RS00970	COG4948	Mandelate Racemase Muconate Lactonizing
FIU94_RS00980	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS00985	COG0583	DNA-binding transcription factor activity
FIU94_RS00995	COG2135	peptidase activity
FIU94_RS01000	COG0737	Belongs to the 5'-nucleotidase family
FIU94_RS01015	COG0167	dihydroorotate dehydrogenase activity
FIU94_RS01025	COG0534	Mate efflux family protein
FIU94_RS01050	COG2197	response regulator
FIU94_RS01055	COG0789	Transcriptional regulator
FIU94_RS01060	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS01070	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS01075	COG0625	glutathione transferase activity
FIU94_RS01080	COG0183	Belongs to the thiolase family
FIU94_RS01090	COG1024	Enoyl-CoA hydratase
FIU94_RS01090	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU94_RS01150	COG0318	PFAM AMP-dependent synthetase and ligase
FIU94_RS01170	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FIU94_RS01175	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FIU94_RS01180	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FIU94_RS01190	COG0281	malic enzyme
FIU94_RS01190	COG0280	phosphate acetyltransferase
FIU94_RS01215	COG3237	CsbD-like
FIU94_RS01220	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FIU94_RS01225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIU94_RS01245	COG0596	Alpha beta hydrolase
FIU94_RS01250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU94_RS01260	COG1716	ATPase activity
FIU94_RS01260	COG5001	Diguanylate cyclase
FIU94_RS01280	COG1435	thymidine kinase activity
FIU94_RS01285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU94_RS01305	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FIU94_RS01315	COG1496	oxidoreductase activity
FIU94_RS01325	COG1522	sequence-specific DNA binding
FIU94_RS01330	COG0492	ferredoxin-NADP+ reductase activity
FIU94_RS01340	COG0529	Catalyzes the synthesis of activated sulfate
FIU94_RS01340	COG2046	Belongs to the sulfate adenylyltransferase family
FIU94_RS01350	COG0384	phenazine biosynthesis protein PhzF
FIU94_RS01360	COG0071	Belongs to the small heat shock protein (HSP20) family
FIU94_RS01370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FIU94_RS01375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FIU94_RS01380	COG3454	Phosphonate metabolism
FIU94_RS01395	COG1309	transcriptional regulator
FIU94_RS01405	COG0459	protein refolding
FIU94_RS01410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FIU94_RS01425	COG1227	inorganic diphosphatase activity
FIU94_RS01435	COG2030	dehydratase
FIU94_RS01440	COG0196	riboflavin kinase activity
FIU94_RS01445	COG2983	Belongs to the UPF0260 family
FIU94_RS01455	COG2267	carboxylic ester hydrolase activity
FIU94_RS01475	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FIU94_RS01480	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FIU94_RS01485	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FIU94_RS01490	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FIU94_RS01495	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIU94_RS01505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU94_RS01530	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FIU94_RS01545	COG0287	Prephenate dehydrogenase
FIU94_RS01550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIU94_RS01555	COG5310	Homospermidine synthase
FIU94_RS01570	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FIU94_RS01575	COG3920	Histidine kinase
FIU94_RS01585	COG2818	Glycosylase
FIU94_RS01610	COG0583	DNA-binding transcription factor activity
FIU94_RS01635	COG0142	geranyltranstransferase activity
FIU94_RS01640	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FIU94_RS01655	COG0789	Transcriptional regulator
FIU94_RS01665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIU94_RS01675	COG0303	'Molybdopterin
FIU94_RS01680	COG1763	Mo-molybdopterin cofactor biosynthetic process
FIU94_RS01685	COG0746	molybdenum cofactor guanylyltransferase activity
FIU94_RS01690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FIU94_RS01725	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS01730	COG0009	L-threonylcarbamoyladenylate synthase
FIU94_RS01735	COG1678	Uncharacterized ACR, COG1678
FIU94_RS01745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU94_RS01755	COG3768	UPF0283 membrane protein
FIU94_RS01765	COG3106	COG3106 Predicted ATPase
FIU94_RS01770	COG0101	tRNA pseudouridine synthase activity
FIU94_RS01775	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FIU94_RS01785	COG0306	phosphate transporter
FIU94_RS01800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FIU94_RS01815	COG0028	Belongs to the TPP enzyme family
FIU94_RS01820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU94_RS01840	COG2943	transferase activity, transferring hexosyl groups
FIU94_RS01890	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FIU94_RS01900	COG0521	Mo-molybdopterin cofactor biosynthetic process
FIU94_RS01905	COG1280	lysine exporter protein (LysE YggA)
FIU94_RS01910	COG1573	uracil-dna glycosylase
FIU94_RS01915	COG0540	Belongs to the ATCase OTCase family
FIU94_RS01930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FIU94_RS01935	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FIU94_RS01980	COG0314	molybdopterin synthase activity
FIU94_RS01990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIU94_RS01995	COG0322	excinuclease ABC activity
FIU94_RS02000	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS02015	COG0842	Transport permease protein
FIU94_RS02020	COG1131	(ABC) transporter
FIU94_RS02030	COG0697	spore germination
FIU94_RS02035	COG3321	synthase
FIU94_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS02035	COG0604	alcohol dehydrogenase
FIU94_RS02045	COG1294	oxidase, subunit
FIU94_RS02050	COG1271	oxidase subunit
FIU94_RS02055	COG2205	protein histidine kinase activity
FIU94_RS02060	COG0745	RESPONSE REGULATOR receiver
FIU94_RS02075	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FIU94_RS02080	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIU94_RS02090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU94_RS02105	COG3971	2-oxopent-4-enoate hydratase activity
FIU94_RS02110	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIU94_RS02120	COG1012	belongs to the aldehyde dehydrogenase family
FIU94_RS02140	COG2212	antiporter activity
FIU94_RS02145	COG1863	multisubunit Na H antiporter MnhE subunit
FIU94_RS02150	COG0651	ATP synthesis coupled electron transport
FIU94_RS02155	COG1006	Multisubunit Na H antiporter MnhC subunit
FIU94_RS02160	COG2111	Na H antiporter
FIU94_RS02160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FIU94_RS02165	COG0318	PFAM AMP-dependent synthetase and ligase
FIU94_RS02170	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU94_RS02170	COG1024	Enoyl-CoA hydratase
FIU94_RS02175	COG1024	Enoyl-CoA hydratase
FIU94_RS02185	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS02190	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS02200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FIU94_RS02205	COG1946	Acyl-CoA thioesterase
FIU94_RS02210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU94_RS02265	COG0183	Belongs to the thiolase family
FIU94_RS02270	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS02280	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS02285	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS02300	COG2130	NADP-dependent
FIU94_RS02320	COG0174	glutamine synthetase
FIU94_RS02325	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU94_RS02355	COG2217	Heavy metal translocating P-type atpase
FIU94_RS02365	COG0348	domain, Protein
FIU94_RS02370	COG2010	Cytochrome c
FIU94_RS02390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIU94_RS02395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU94_RS02400	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FIU94_RS02410	COG4638	Rieske (2fe-2S)
FIU94_RS02415	COG1902	pentaerythritol trinitrate reductase activity
FIU94_RS02415	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU94_RS02430	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FIU94_RS02435	COG1530	ribonuclease E activity
FIU94_RS02445	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FIU94_RS02450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU94_RS02455	COG0583	DNA-binding transcription factor activity
FIU94_RS02480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIU94_RS02495	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FIU94_RS02500	COG1183	phosphatidylcholine synthase activity
FIU94_RS02510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIU94_RS02520	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FIU94_RS02525	COG0135	phosphoribosylanthranilate isomerase activity
FIU94_RS02535	COG0776	regulation of translation
FIU94_RS02540	COG0539	negative regulation of cytoplasmic translation
FIU94_RS02545	COG1376	ErfK ybiS ycfS ynhG family protein
FIU94_RS02565	COG3842	ATPase activity
FIU94_RS02580	COG1177	transmembrane transport
FIU94_RS02600	COG0427	acetyl-CoA hydrolase
FIU94_RS02605	COG3608	succinylglutamate desuccinylase aspartoacylase
FIU94_RS02610	COG0006	proline dipeptidase activity
FIU94_RS02615	COG1522	sequence-specific DNA binding
FIU94_RS02620	COG1012	belongs to the aldehyde dehydrogenase family
FIU94_RS02625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU94_RS02650	COG0667	Aldo Keto reductase
FIU94_RS02675	COG2951	lytic endotransglycosylase activity
FIU94_RS02700	COG3852	Histidine kinase
FIU94_RS02715	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FIU94_RS02720	COG0594	ribonuclease P activity
FIU94_RS02725	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FIU94_RS02735	COG0037	tRNA processing
FIU94_RS02745	COG0706	membrane insertase activity
FIU94_RS02755	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FIU94_RS02760	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FIU94_RS02775	COG1126	abc transporter atp-binding protein
FIU94_RS02780	COG0765	amino acid transport
FIU94_RS02785	COG4597	amino acid ABC transporter
FIU94_RS02790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU94_RS02800	COG0546	phosphoglycolate phosphatase activity
FIU94_RS02810	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FIU94_RS02815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FIU94_RS02820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU94_RS02825	COG0203	ribosomal protein L17
FIU94_RS02830	COG0202	RNA polymerase activity
FIU94_RS02835	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FIU94_RS02840	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIU94_RS02845	COG0563	adenylate kinase activity
FIU94_RS02850	COG0201	protein transport
FIU94_RS02855	COG0200	Binds to the 23S rRNA
FIU94_RS02875	COG1841	ribosomal large subunit assembly
FIU94_RS02880	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FIU94_RS02885	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FIU94_RS02890	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FIU94_RS02895	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FIU94_RS02900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FIU94_RS02905	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FIU94_RS02910	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FIU94_RS02915	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FIU94_RS02920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FIU94_RS02925	COG0255	Belongs to the universal ribosomal protein uL29 family
FIU94_RS02950	COG0051	transcription antitermination factor activity, RNA binding
FIU94_RS02955	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FIU94_RS02960	COG0088	Forms part of the polypeptide exit tunnel
FIU94_RS02965	COG0089	rRNA binding
FIU94_RS02970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FIU94_RS02975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FIU94_RS02980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FIU94_RS02985	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FIU94_RS02990	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FIU94_RS03000	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU94_RS03010	COG2124	cytochrome p450
FIU94_RS03010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FIU94_RS03015	COG0501	Belongs to the peptidase M48B family
FIU94_RS03025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIU94_RS03035	COG0300	oxidoreductase activity
FIU94_RS03045	COG2096	Adenosyltransferase
FIU94_RS03065	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU94_RS03075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU94_RS03085	COG1660	Displays ATPase and GTPase activities
FIU94_RS03095	COG2205	protein histidine kinase activity
FIU94_RS03100	COG0745	RESPONSE REGULATOR receiver
FIU94_RS03105	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FIU94_RS03120	COG1396	sequence-specific DNA binding
FIU94_RS03145	COG1381	Involved in DNA repair and RecF pathway recombination
FIU94_RS03155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FIU94_RS03160	COG0571	ribonuclease III activity
FIU94_RS03165	COG0681	Belongs to the peptidase S26 family
FIU94_RS03170	COG0736	holo-[acyl-carrier-protein] synthase activity
FIU94_RS03180	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FIU94_RS03190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIU94_RS03195	COG1758	RNA polymerase activity
FIU94_RS03200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FIU94_RS03210	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FIU94_RS03225	COG4106	trans-aconitate 2-methyltransferase activity
FIU94_RS03230	COG0328	RNA-DNA hybrid ribonuclease activity
FIU94_RS03235	COG2860	membrane
FIU94_RS03245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FIU94_RS03260	COG0242	peptide deformylase activity
FIU94_RS03265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FIU94_RS03275	COG0435	Glutathione S-transferase
FIU94_RS03290	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FIU94_RS03320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FIU94_RS03330	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FIU94_RS03335	COG0356	it plays a direct role in the translocation of protons across the membrane
FIU94_RS03345	COG0583	DNA-binding transcription factor activity
FIU94_RS03370	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FIU94_RS03375	COG0471	metal ion transport
FIU94_RS03375	COG3273	potassium ion transport
FIU94_RS03380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FIU94_RS03395	COG0228	four-way junction DNA binding
FIU94_RS03400	COG0778	Nitroreductase
FIU94_RS03405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FIU94_RS03415	COG0336	Belongs to the RNA methyltransferase TrmD family
FIU94_RS03420	COG2151	metal-sulfur cluster biosynthetic enzyme
FIU94_RS03420	COG0489	protein tyrosine kinase activity
FIU94_RS03430	COG0254	rRNA binding
FIU94_RS03435	COG0335	large ribosomal subunit rRNA binding
FIU94_RS03455	COG4948	Mandelate Racemase Muconate Lactonizing
FIU94_RS03465	COG2301	Belongs to the HpcH HpaI aldolase family
FIU94_RS03470	COG0825	malonyl-CoA metabolic process
FIU94_RS03510	COG0583	DNA-binding transcription factor activity
FIU94_RS03515	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FIU94_RS03525	COG0587	DNA-directed DNA polymerase activity
FIU94_RS03545	COG0513	Belongs to the DEAD box helicase family
FIU94_RS03550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU94_RS03555	COG1116	anion transmembrane transporter activity
FIU94_RS03565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU94_RS03575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU94_RS03580	COG0028	Belongs to the TPP enzyme family
FIU94_RS03585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FIU94_RS03595	COG0243	molybdopterin cofactor binding
FIU94_RS03600	COG0437	4 iron, 4 sulfur cluster binding
FIU94_RS03610	COG1473	amidohydrolase
FIU94_RS03615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIU94_RS03620	COG0741	lytic transglycosylase activity
FIU94_RS03625	COG0697	spore germination
FIU94_RS03650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIU94_RS03650	COG2169	Transcriptional regulator
FIU94_RS03655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FIU94_RS03660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIU94_RS03670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIU94_RS03675	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIU94_RS03680	COG0049	tRNA binding
FIU94_RS03685	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FIU94_RS03700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FIU94_RS03705	COG0085	RNA polymerase activity
FIU94_RS03710	COG0222	ribosome binding
FIU94_RS03715	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FIU94_RS03720	COG0081	regulation of translation
FIU94_RS03725	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FIU94_RS03730	COG0250	Participates in transcription elongation, termination and antitermination
FIU94_RS03755	COG1137	ATPase activity
FIU94_RS03775	COG0154	amidase activity
FIU94_RS03800	COG1051	belongs to the nudix hydrolase family
FIU94_RS03810	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU94_RS03810	COG1902	pentaerythritol trinitrate reductase activity
FIU94_RS03820	COG0583	DNA-binding transcription factor activity
FIU94_RS03840	COG1546	Belongs to the CinA family
FIU94_RS03840	COG1058	Belongs to the CinA family
FIU94_RS03845	COG1489	DNA binding
FIU94_RS03850	COG0024	Methionine aminopeptidase
FIU94_RS03855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU94_RS03860	COG0742	ribosomal rna small subunit methyltransferase
FIU94_RS03870	COG0678	peroxiredoxin activity
FIU94_RS03875	COG0668	transmembrane transport
FIU94_RS03880	COG2154	pterin-4-alpha-carbinolamine dehydratase
FIU94_RS03900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIU94_RS03910	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FIU94_RS03920	COG0004	ammonium transporteR
FIU94_RS03935	COG2897	thiosulfate sulfurtransferase activity
FIU94_RS03940	COG0625	glutathione transferase activity
FIU94_RS03945	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FIU94_RS04015	COG1012	belongs to the aldehyde dehydrogenase family
FIU94_RS04040	COG0247	lactate metabolic process
FIU94_RS04050	COG0277	FAD linked oxidase domain protein
FIU94_RS04055	COG0277	FAD linked oxidase domain protein
FIU94_RS04070	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FIU94_RS04075	COG0799	negative regulation of ribosome biogenesis
FIU94_RS04085	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FIU94_RS04085	COG3264	Mechanosensitive ion channel
FIU94_RS04090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FIU94_RS04100	COG0066	3-isopropylmalate dehydratase activity
FIU94_RS04115	COG0473	3-isopropylmalate dehydrogenase activity
FIU94_RS04120	COG0697	spore germination
FIU94_RS04150	COG1609	Transcriptional regulator
FIU94_RS04155	COG3214	Protein conserved in bacteria
FIU94_RS04160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU94_RS04165	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU94_RS04175	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU94_RS04175	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU94_RS04185	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FIU94_RS04195	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FIU94_RS04210	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FIU94_RS04215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIU94_RS04235	COG0625	glutathione transferase activity
FIU94_RS04240	COG2808	Putative FMN-binding domain
FIU94_RS04250	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FIU94_RS04260	COG4143	(ABC) transporter
FIU94_RS04265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FIU94_RS04280	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS04295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FIU94_RS04300	COG1846	Transcriptional regulator
FIU94_RS04305	COG0745	RESPONSE REGULATOR receiver
FIU94_RS04310	COG1722	exodeoxyribonuclease VII activity
FIU94_RS04315	COG0142	geranyltranstransferase activity
FIU94_RS04320	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FIU94_RS04345	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU94_RS04385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FIU94_RS04390	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FIU94_RS04410	COG0438	transferase activity, transferring glycosyl groups
FIU94_RS04415	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FIU94_RS04425	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU94_RS04430	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU94_RS04445	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FIU94_RS04455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FIU94_RS04670	COG3008	intermembrane lipid transfer
FIU94_RS04675	COG2995	paraquat-inducible protein a
FIU94_RS04685	COG0693	protein deglycase activity
FIU94_RS04690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU94_RS04700	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU94_RS04720	COG2358	TRAP transporter, solute receptor (TAXI family
FIU94_RS04725	COG0069	glutamate synthase activity
FIU94_RS04735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIU94_RS04760	COG0784	Response regulator, receiver
FIU94_RS04765	COG4575	ribosome binding
FIU94_RS04785	COG1295	ribonuclease BN
FIU94_RS04790	COG2116	formate transmembrane transporter activity
FIU94_RS04805	COG0443	Heat shock 70 kDa protein
FIU94_RS04810	COG0747	negative chemotaxis
FIU94_RS04815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FIU94_RS04825	COG2226	methyltransferase
FIU94_RS04830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIU94_RS04835	COG1024	Enoyl-CoA hydratase
FIU94_RS04840	COG0268	Binds directly to 16S ribosomal RNA
FIU94_RS04845	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIU94_RS04855	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FIU94_RS04870	COG0183	Belongs to the thiolase family
FIU94_RS04875	COG3396	Phenylacetate-CoA oxygenase
FIU94_RS04880	COG3460	Phenylacetate-CoA oxygenase
FIU94_RS04885	COG3396	Phenylacetate-CoA oxygenase
FIU94_RS04890	COG2151	metal-sulfur cluster biosynthetic enzyme
FIU94_RS04895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU94_RS04900	COG2030	dehydratase
FIU94_RS04900	COG1012	belongs to the aldehyde dehydrogenase family
FIU94_RS04905	COG3327	negative regulation of DNA-templated transcription, initiation
FIU94_RS04910	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FIU94_RS04915	COG0517	IMP dehydrogenase activity
FIU94_RS04915	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FIU94_RS04930	COG1137	ATPase activity
FIU94_RS04935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FIU94_RS04940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FIU94_RS04965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIU94_RS04980	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FIU94_RS04985	COG1218	3'(2'),5'-bisphosphate nucleotidase
FIU94_RS04995	COG0443	Heat shock 70 kDa protein
FIU94_RS05000	COG0484	heat shock protein binding
FIU94_RS05005	COG2003	Belongs to the UPF0758 family
FIU94_RS05020	COG0653	protein targeting
FIU94_RS05025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIU94_RS05030	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FIU94_RS05035	COG0494	nUDIX hydrolase
FIU94_RS05050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FIU94_RS05065	COG0779	Required for maturation of 30S ribosomal subunits
FIU94_RS05080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIU94_RS05090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU94_RS05100	COG1040	competence protein
FIU94_RS05130	COG3034	peptidoglycan biosynthetic process
FIU94_RS05135	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FIU94_RS05140	COG1132	(ABC) transporter
FIU94_RS05145	COG1132	(ABC) transporter
FIU94_RS05150	COG0617	tRNA 3'-terminal CCA addition
FIU94_RS05155	COG0494	nUDIX hydrolase
FIU94_RS05165	COG0494	nUDIX hydrolase
FIU94_RS05180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FIU94_RS05185	COG0137	argininosuccinate synthase activity
FIU94_RS05210	COG0444	Belongs to the ABC transporter superfamily
FIU94_RS05215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU94_RS05220	COG0601	transmembrane transport
FIU94_RS05225	COG4533	DNA binding
FIU94_RS05235	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FIU94_RS05275	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS05280	COG3246	L-lysine catabolic process to acetate
FIU94_RS05285	COG3485	protocatechuate 3,4-dioxygenase
FIU94_RS05290	COG3485	protocatechuate 3,4-dioxygenase
FIU94_RS05295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FIU94_RS05300	COG0583	DNA-binding transcription factor activity
FIU94_RS05305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIU94_RS05315	COG0281	malic enzyme
FIU94_RS05315	COG0280	phosphate acetyltransferase
FIU94_RS05325	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FIU94_RS05330	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FIU94_RS05335	COG1420	regulation of RNA biosynthetic process
FIU94_RS05340	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FIU94_RS05345	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FIU94_RS05350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIU94_RS05365	COG0357	Ribosomal RNA small subunit methyltransferase G
FIU94_RS05370	COG0445	tRNA wobble uridine modification
FIU94_RS05375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FIU94_RS05380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FIU94_RS05385	COG1981	membrane
FIU94_RS05390	COG0424	maF-like protein
FIU94_RS05395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIU94_RS05400	COG0237	dephospho-CoA kinase activity
FIU94_RS05405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FIU94_RS05410	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FIU94_RS05440	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FIU94_RS05445	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FIU94_RS05470	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FIU94_RS05475	COG3178	'Phosphotransferase
FIU94_RS05480	COG0802	atpase or kinase
FIU94_RS05495	COG1999	signal sequence binding
FIU94_RS05500	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FIU94_RS05510	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FIU94_RS05520	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FIU94_RS05550	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FIU94_RS05555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FIU94_RS05585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU94_RS05610	COG3191	aminopeptidase activity
FIU94_RS05625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU94_RS05640	COG0183	Belongs to the thiolase family
FIU94_RS05645	COG1396	sequence-specific DNA binding
FIU94_RS05650	COG0156	8-amino-7-oxononanoate synthase activity
FIU94_RS05655	COG1063	alcohol dehydrogenase
FIU94_RS05665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FIU94_RS05680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU94_RS05685	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FIU94_RS05690	COG3830	Belongs to the UPF0237 family
FIU94_RS05690	COG0560	Phosphoserine phosphatase
FIU94_RS05710	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FIU94_RS05725	COG2171	N-acyltransferase activity
FIU94_RS05755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU94_RS05760	COG2153	protein acetylation
FIU94_RS05770	COG0557	exoribonuclease II activity
FIU94_RS05780	COG2951	lytic endotransglycosylase activity
FIU94_RS05790	COG1802	Transcriptional regulator
FIU94_RS05800	COG3842	ATPase activity
FIU94_RS05805	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU94_RS05810	COG1177	transmembrane transport
FIU94_RS05815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU94_RS05820	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FIU94_RS05840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FIU94_RS05865	COG1815	bacterial-type flagellum-dependent cell motility
FIU94_RS05870	COG1558	bacterial-type flagellum-dependent cell motility
FIU94_RS05875	COG1677	Flagellar hook-basal body complex protein FliE
FIU94_RS05880	COG1987	bacterial-type flagellum assembly
FIU94_RS05885	COG4786	Flagellar basal body rod
FIU94_RS05890	COG4786	Flagellar basal body rod
FIU94_RS05900	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FIU94_RS05915	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIU94_RS05925	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FIU94_RS05935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FIU94_RS05955	COG1766	The M ring may be actively involved in energy transduction
FIU94_RS05965	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FIU94_RS05970	COG1338	Plays a role in the flagellum-specific transport system
FIU94_RS05980	COG1706	bacterial-type flagellum-dependent cell motility
FIU94_RS06000	COG1360	Flagellar Motor Protein
FIU94_RS06005	COG1054	Belongs to the UPF0176 family
FIU94_RS06010	COG1335	isochorismatase
FIU94_RS06015	COG2095	MarC family integral membrane protein
FIU94_RS06025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FIU94_RS06085	COG2099	Precorrin-6x reductase
FIU94_RS06100	COG2875	Belongs to the precorrin methyltransferase family
FIU94_RS06105	COG1797	cobyrinic acid a,c-diamide synthase activity
FIU94_RS06110	COG1648	precorrin-2 dehydrogenase activity
FIU94_RS06110	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU94_RS06130	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FIU94_RS06140	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FIU94_RS06165	COG0514	ATP-dependent DNA helicase (RecQ)
FIU94_RS06175	COG3022	response to hydroperoxide
FIU94_RS06180	COG0784	Response regulator, receiver
FIU94_RS06180	COG5002	protein histidine kinase activity
FIU94_RS06180	COG2205	protein histidine kinase activity
FIU94_RS06185	COG2373	Large extracellular alpha-helical protein
FIU94_RS06190	COG4953	penicillin-binding protein 1C
FIU94_RS06220	COG0714	Associated with various cellular activities
FIU94_RS06230	COG3622	Belongs to the hyi family
FIU94_RS06245	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU94_RS06245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIU94_RS06255	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FIU94_RS06265	COG0793	Belongs to the peptidase S41A family
FIU94_RS06290	COG0129	dihydroxy-acid dehydratase activity
FIU94_RS06305	COG2274	protein secretion by the type I secretion system
FIU94_RS06310	COG1266	CAAX protease self-immunity
FIU94_RS06315	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FIU94_RS06320	COG0285	dihydrofolate synthase activity
FIU94_RS06330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FIU94_RS06340	COG2423	ornithine cyclodeaminase activity
FIU94_RS06350	COG1671	Belongs to the UPF0178 family
FIU94_RS06355	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FIU94_RS06360	COG0679	Auxin Efflux Carrier
FIU94_RS06380	COG2050	protein possibly involved in aromatic compounds catabolism
FIU94_RS06390	COG0791	NLP P60 protein
FIU94_RS06395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIU94_RS06405	COG0288	reversible hydration of carbon dioxide
FIU94_RS06415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIU94_RS06450	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FIU94_RS06470	COG1194	a g-specific adenine glycosylase
FIU94_RS06485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU94_RS06490	COG1663	tetraacyldisaccharide 4'-kinase activity
FIU94_RS06510	COG0312	modulator of DNA gyrase
FIU94_RS06520	COG0300	oxidoreductase activity
FIU94_RS06555	COG0495	leucyl-tRNA aminoacylation
FIU94_RS06570	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FIU94_RS06590	COG0745	RESPONSE REGULATOR receiver
FIU94_RS06605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU94_RS06610	COG2835	tetraacyldisaccharide 4'-kinase activity
FIU94_RS06615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU94_RS06620	COG0154	amidase activity
FIU94_RS06625	COG0436	Aminotransferase
FIU94_RS06630	COG1674	ftsk spoiiie
FIU94_RS06660	COG0405	Gamma-glutamyltransferase
FIU94_RS06670	COG1366	Belongs to the anti-sigma-factor antagonist family
FIU94_RS06690	COG1280	lysine exporter protein (LysE YggA)
FIU94_RS06725	COG0450	alkyl hydroperoxide reductase
FIU94_RS06745	COG0564	pseudouridine synthase activity
FIU94_RS06765	COG1185	polyribonucleotide nucleotidyltransferase activity
FIU94_RS06780	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FIU94_RS06795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FIU94_RS06805	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FIU94_RS06810	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FIU94_RS06825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIU94_RS06825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU94_RS06840	COG0138	bifunctional purine biosynthesis protein purh
FIU94_RS06845	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FIU94_RS06855	COG0612	Peptidase, M16
FIU94_RS06860	COG0612	Peptidase, M16
FIU94_RS06865	COG1012	belongs to the aldehyde dehydrogenase family
FIU94_RS06880	COG0745	RESPONSE REGULATOR receiver
FIU94_RS06885	COG5002	protein histidine kinase activity
FIU94_RS06890	COG0803	Belongs to the bacterial solute-binding protein 9 family
FIU94_RS06895	COG1121	(ABC) transporter
FIU94_RS06900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU94_RS06905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU94_RS06910	COG2351	hydroxyisourate hydrolase activity
FIU94_RS06920	COG3257	ureidoglycine aminohydrolase activity
FIU94_RS06925	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FIU94_RS06940	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FIU94_RS06975	COG0625	glutathione transferase activity
FIU94_RS06985	COG3383	formate dehydrogenase (NAD+) activity
FIU94_RS07005	COG4191	Histidine kinase
FIU94_RS07040	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FIU94_RS07045	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIU94_RS07045	COG0678	peroxiredoxin activity
FIU94_RS07050	COG1178	ABC-type Fe3 transport system permease component
FIU94_RS07055	COG0625	glutathione transferase activity
FIU94_RS07065	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FIU94_RS07085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FIU94_RS07095	COG0284	orotidine-5'-phosphate decarboxylase activity
FIU94_RS07105	COG0542	response to heat
FIU94_RS07110	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FIU94_RS07115	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FIU94_RS07155	COG1063	alcohol dehydrogenase
FIU94_RS07165	COG2072	flavoprotein involved in K transport
FIU94_RS07170	COG3284	Transcriptional regulator
FIU94_RS07175	COG2514	catechol 2,3-dioxygenase activity
FIU94_RS07185	COG0778	Nitroreductase
FIU94_RS07200	COG0346	lactoylglutathione lyase activity
FIU94_RS07205	COG0745	RESPONSE REGULATOR receiver
FIU94_RS07235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FIU94_RS07255	COG0180	Tryptophanyl-tRNA synthetase
FIU94_RS07270	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FIU94_RS07280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FIU94_RS07285	COG0792	nuclease activity
FIU94_RS07300	COG0606	chelatase, subunit chli
FIU94_RS07310	COG0406	alpha-ribazole phosphatase activity
FIU94_RS07330	COG0756	dUTP diphosphatase activity
FIU94_RS07335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FIU94_RS07340	COG0339	signal peptide processing
FIU94_RS07345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIU94_RS07350	COG0772	Belongs to the SEDS family
FIU94_RS07355	COG0768	penicillin binding
FIU94_RS07385	COG0469	pyruvate kinase activity
FIU94_RS07395	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FIU94_RS07400	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FIU94_RS07410	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FIU94_RS07420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU94_RS07420	COG0072	phenylalanine-tRNA ligase activity
FIU94_RS07430	COG0625	glutathione transferase activity
FIU94_RS07435	COG1970	mechanosensitive ion channel activity
FIU94_RS07450	COG0686	Belongs to the AlaDH PNT family
FIU94_RS07455	COG1522	sequence-specific DNA binding
FIU94_RS07465	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FIU94_RS07475	COG1122	ATPase activity
FIU94_RS07480	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FIU94_RS07485	COG1268	BioY protein
FIU94_RS07490	COG0183	Belongs to the thiolase family
FIU94_RS07495	COG0318	PFAM AMP-dependent synthetase and ligase
FIU94_RS07500	COG1063	alcohol dehydrogenase
FIU94_RS07525	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FIU94_RS07530	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FIU94_RS07535	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FIU94_RS07545	COG2321	neutral zinc metallopeptidase
FIU94_RS07560	COG0737	Belongs to the 5'-nucleotidase family
FIU94_RS07565	COG2816	NAD+ diphosphatase activity
FIU94_RS07590	COG0077	Prephenate dehydratase
FIU94_RS07605	COG4174	ABC transporter (Permease)
FIU94_RS07610	COG4239	(ABC) transporter, permease
FIU94_RS07615	COG4172	Belongs to the ABC transporter superfamily
FIU94_RS07620	COG0583	DNA-binding transcription factor activity
FIU94_RS07625	COG1686	Belongs to the peptidase S11 family
FIU94_RS07635	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FIU94_RS07655	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FIU94_RS07680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU94_RS07715	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FIU94_RS07725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU94_RS07740	COG3046	protein related to deoxyribodipyrimidine photolyase
FIU94_RS07750	COG0655	NAD(P)H dehydrogenase (quinone) activity
FIU94_RS07770	COG2070	2-Nitropropane dioxygenase
FIU94_RS07780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU94_RS07795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU94_RS07800	COG0509	glycine decarboxylation via glycine cleavage system
FIU94_RS07805	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIU94_RS07805	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FIU94_RS07820	COG4181	ATPase activity
FIU94_RS07835	COG1278	Cold shock
FIU94_RS07855	COG1309	transcriptional regulator
FIU94_RS07875	COG1116	anion transmembrane transporter activity
FIU94_RS07880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU94_RS07885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU94_RS07895	COG1376	ErfK ybiS ycfS ynhG family protein
FIU94_RS07900	COG0745	RESPONSE REGULATOR receiver
FIU94_RS07905	COG0488	(ABC) transporter
FIU94_RS07910	COG4191	Histidine kinase
FIU94_RS07920	COG1115	amino acid carrier protein
FIU94_RS07925	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FIU94_RS07930	COG0697	spore germination
FIU94_RS07955	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FIU94_RS07990	COG0556	nucleotide-excision repair
FIU94_RS08020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FIU94_RS08030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIU94_RS08035	COG5328	Belongs to the UPF0262 family
FIU94_RS08060	COG0481	GTPase activity
FIU94_RS08090	COG0438	transferase activity, transferring glycosyl groups
FIU94_RS08105	COG0668	transmembrane transport
FIU94_RS08110	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FIU94_RS08115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU94_RS08120	COG0601	transmembrane transport
FIU94_RS08145	COG1024	Enoyl-CoA hydratase
FIU94_RS08145	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU94_RS08150	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS08155	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS08165	COG1024	Enoyl-CoA hydratase
FIU94_RS08170	COG0318	PFAM AMP-dependent synthetase and ligase
FIU94_RS08195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIU94_RS08210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU94_RS08255	COG1840	ABC-type Fe3 transport system, periplasmic component
FIU94_RS08260	COG3454	Phosphonate metabolism
FIU94_RS08265	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FIU94_RS08275	COG4778	phosphonate C-P lyase system protein PhnL
FIU94_RS08280	COG4107	phosphonate C-P lyase system protein PhnK
FIU94_RS08285	COG3627	carbon phosphorus lyase activity
FIU94_RS08290	COG2852	Protein conserved in bacteria
FIU94_RS08295	COG3626	phosphonate metabolism
FIU94_RS08300	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FIU94_RS08305	COG3624	Phosphonate C-P lyase system protein PhnG
FIU94_RS08310	COG2188	Transcriptional regulator
FIU94_RS08320	COG3639	organic phosphonate transmembrane transporter activity
FIU94_RS08325	COG3639	organic phosphonate transmembrane transporter activity
FIU94_RS08330	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FIU94_RS08335	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FIU94_RS08340	COG0129	dihydroxy-acid dehydratase activity
FIU94_RS08345	COG0800	Aldolase
FIU94_RS08370	COG1177	transmembrane transport
FIU94_RS08375	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU94_RS08380	COG3842	ATPase activity
FIU94_RS08390	COG0033	Phosphoglucomutase
FIU94_RS08395	COG0028	Belongs to the TPP enzyme family
FIU94_RS08395	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
FIU94_RS08405	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIU94_RS08410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FIU94_RS08415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU94_RS08430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FIU94_RS08440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FIU94_RS08450	COG0527	aspartate kinase activity
FIU94_RS08455	COG1917	Cupin 2, conserved barrel domain protein
FIU94_RS08460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FIU94_RS08465	COG0456	acetyltransferase
FIU94_RS08485	COG2358	TRAP transporter, solute receptor (TAXI family
FIU94_RS08500	COG4191	Histidine kinase
FIU94_RS08510	COG1120	ATPase activity
FIU94_RS08515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU94_RS08540	COG0604	alcohol dehydrogenase
FIU94_RS08555	COG0405	Gamma-glutamyltransferase
FIU94_RS08560	COG0277	FAD linked oxidase domain protein
FIU94_RS08610	COG1079	Belongs to the binding-protein-dependent transport system permease family
FIU94_RS08615	COG4603	Belongs to the binding-protein-dependent transport system permease family
FIU94_RS08620	COG3845	ABC transporter
FIU94_RS08630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIU94_RS08665	COG0124	histidyl-tRNA synthetase
FIU94_RS08670	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FIU94_RS08675	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FIU94_RS08775	COG1609	Transcriptional regulator
FIU94_RS08785	COG3773	Cell wall hydrolase
FIU94_RS08785	COG3409	Peptidoglycan-binding domain 1 protein
FIU94_RS08805	COG3845	ABC transporter
FIU94_RS08810	COG4603	Belongs to the binding-protein-dependent transport system permease family
FIU94_RS08815	COG1079	Belongs to the binding-protein-dependent transport system permease family
FIU94_RS08820	COG0402	S-adenosylhomocysteine deaminase activity
FIU94_RS08850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU94_RS08855	COG0165	Argininosuccinate lyase
FIU94_RS08870	COG0019	diaminopimelate decarboxylase activity
FIU94_RS08885	COG2884	Cell division ATP-binding protein ftsE
FIU94_RS08930	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU94_RS08935	COG0567	Dehydrogenase, E1 component
FIU94_RS08965	COG0045	succinate-CoA ligase (ADP-forming) activity
FIU94_RS08975	COG2030	dehydratase
FIU94_RS09010	COG0039	L-malate dehydrogenase activity
FIU94_RS09065	COG0813	purine-nucleoside phosphorylase activity
FIU94_RS09075	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU94_RS09075	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FIU94_RS09090	COG0604	alcohol dehydrogenase
FIU94_RS09110	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIU94_RS09115	COG4221	oxidoreductase activity
FIU94_RS09125	COG0730	response to heat
FIU94_RS09135	COG1079	Belongs to the binding-protein-dependent transport system permease family
FIU94_RS09140	COG4603	Belongs to the binding-protein-dependent transport system permease family
FIU94_RS09145	COG3845	ABC transporter
FIU94_RS09150	COG1744	ABC transporter substrate-binding protein PnrA-like
FIU94_RS09160	COG1214	PFAM Peptidase M22, glycoprotease
FIU94_RS09165	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FIU94_RS09215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIU94_RS09225	COG0133	tryptophan synthase activity
FIU94_RS09250	COG0193	aminoacyl-tRNA hydrolase activity
FIU94_RS09260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FIU94_RS09275	COG1304	FMN binding
FIU94_RS09280	COG0159	tryptophan synthase activity
FIU94_RS09290	COG0012	GTP binding
FIU94_RS09370	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU94_RS09385	COG4974	Belongs to the 'phage' integrase family
FIU94_RS09395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU94_RS09420	COG5002	protein histidine kinase activity
FIU94_RS09425	COG5002	protein histidine kinase activity
FIU94_RS09430	COG0745	RESPONSE REGULATOR receiver
FIU94_RS09440	COG0745	RESPONSE REGULATOR receiver
FIU94_RS09445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIU94_RS09485	COG1643	Atp-dependent helicase
FIU94_RS09490	COG1703	isobutyryl-CoA mutase activity
FIU94_RS09505	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIU94_RS09545	COG0632	four-way junction helicase activity
FIU94_RS09550	COG2255	four-way junction helicase activity
FIU94_RS09560	COG0824	Thioesterase
FIU94_RS09580	COG0823	Involved in the tonB-independent uptake of proteins
FIU94_RS09585	COG2885	chlorophyll binding
FIU94_RS09595	COG0037	tRNA processing
FIU94_RS09600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIU94_RS09615	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FIU94_RS09620	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FIU94_RS09640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIU94_RS09660	COG1201	RNA secondary structure unwinding
FIU94_RS09710	COG4964	Belongs to the GSP D family
FIU94_RS09740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FIU94_RS09750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FIU94_RS09750	COG1754	DNA topoisomerase type I activity
FIU94_RS09755	COG0758	DNA mediated transformation
FIU94_RS09760	COG0312	modulator of DNA gyrase
FIU94_RS09770	COG0109	protoheme IX farnesyltransferase activity
FIU94_RS09780	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FIU94_RS09790	COG3346	SURF1 family
FIU94_RS09815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FIU94_RS09830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIU94_RS09835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIU94_RS09840	COG1280	lysine exporter protein (LysE YggA)
FIU94_RS09845	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FIU94_RS09855	COG0659	secondary active sulfate transmembrane transporter activity
FIU94_RS09860	COG1162	GTPase activity
FIU94_RS09865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIU94_RS09885	COG4149	molybdate abc transporter
FIU94_RS09890	COG0725	ABC transporter, periplasmic molybdate-binding protein
FIU94_RS09915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIU94_RS09925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU94_RS09930	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS09935	COG0318	PFAM AMP-dependent synthetase and ligase
FIU94_RS09960	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FIU94_RS10020	COG1396	sequence-specific DNA binding
FIU94_RS10055	COG0582	viral genome integration into host DNA
FIU94_RS10070	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FIU94_RS10085	COG1492	cobalamin metabolic process
FIU94_RS10095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FIU94_RS10100	COG0354	folic acid binding
FIU94_RS10110	COG1132	(ABC) transporter
FIU94_RS10115	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FIU94_RS10120	COG0698	ribose 5-phosphate isomerase
FIU94_RS10140	COG0525	valine-tRNA ligase activity
FIU94_RS10170	COG2130	NADP-dependent
FIU94_RS10175	COG0483	inositol monophosphate 1-phosphatase activity
FIU94_RS10200	COG1522	sequence-specific DNA binding
FIU94_RS10230	COG1072	(Pantothenic acid kinase))
FIU94_RS10275	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FIU94_RS10285	COG0840	transmembrane signaling receptor activity
FIU94_RS10290	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIU94_RS10300	COG0667	Aldo Keto reductase
FIU94_RS10310	COG3246	L-lysine catabolic process to acetate
FIU94_RS10320	COG0824	Thioesterase
FIU94_RS10320	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU94_RS10355	COG1595	DNA-templated transcription, initiation
FIU94_RS10390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIU94_RS10395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU94_RS10400	COG4311	Sarcosine oxidase, delta subunit
FIU94_RS10405	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU94_RS10405	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU94_RS10420	COG0358	DNA primase activity
FIU94_RS10425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIU94_RS10435	COG0432	Pfam Uncharacterised protein family UPF0047
FIU94_RS10440	COG4221	oxidoreductase activity
FIU94_RS10445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FIU94_RS10450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU94_RS10450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIU94_RS10480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU94_RS10480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIU94_RS10485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FIU94_RS10490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIU94_RS10535	COG0564	pseudouridine synthase activity
FIU94_RS10555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FIU94_RS10570	COG0671	phosphoesterase, PA-phosphatase related
FIU94_RS10575	COG1793	dna ligase
FIU94_RS10575	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FIU94_RS10605	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FIU94_RS10610	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FIU94_RS10615	COG1329	Transcriptional regulator
FIU94_RS10620	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FIU94_RS10625	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FIU94_RS10670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIU94_RS10685	COG0140	phosphoribosyl-ATP diphosphatase activity
FIU94_RS10690	COG0107	imidazoleglycerol-phosphate synthase activity
FIU94_RS10695	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIU94_RS10710	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIU94_RS10715	COG0131	Imidazoleglycerol-phosphate dehydratase
FIU94_RS10730	COG0745	RESPONSE REGULATOR receiver
FIU94_RS10740	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FIU94_RS10755	COG0321	lipoyl(octanoyl) transferase activity
FIU94_RS10780	COG1136	(ABC) transporter
FIU94_RS10805	COG0729	surface antigen
FIU94_RS10830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU94_RS10835	COG0569	domain protein
FIU94_RS10840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU94_RS10845	COG0628	permease
FIU94_RS10850	COG0028	Belongs to the TPP enzyme family
FIU94_RS10860	COG1846	Transcriptional regulator
FIU94_RS10910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU94_RS10915	COG1024	Enoyl-CoA hydratase
FIU94_RS10930	COG3781	membrane
FIU94_RS10935	COG1609	Transcriptional regulator
FIU94_RS10940	COG1653	transport
FIU94_RS10945	COG1175	transmembrane transport
FIU94_RS10970	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FIU94_RS10980	COG2986	histidine ammonia-lyase
FIU94_RS10985	COG1228	amidohydrolase
FIU94_RS10995	COG5002	protein histidine kinase activity
FIU94_RS11010	COG0392	lysyltransferase activity
FIU94_RS11010	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FIU94_RS11015	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIU94_RS11020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIU94_RS11025	COG1845	cytochrome c oxidase, subunit III
FIU94_RS11030	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FIU94_RS11040	COG1566	PFAM secretion protein HlyD family protein
FIU94_RS11060	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS11065	COG4689	acetoacetate decarboxylase
FIU94_RS11085	COG2010	Cytochrome c
FIU94_RS11085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIU94_RS11090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIU94_RS11110	COG0210	DNA helicase
FIU94_RS11125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FIU94_RS11130	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FIU94_RS11135	COG2080	2 iron, 2 sulfur cluster binding
FIU94_RS11170	COG0596	Alpha beta hydrolase
FIU94_RS11220	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FIU94_RS11225	COG0732	type I restriction modification DNA specificity domain
FIU94_RS11240	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FIU94_RS11255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU94_RS11260	COG0730	response to heat
FIU94_RS11280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FIU94_RS11285	COG4235	cytochrome complex assembly
FIU94_RS11290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU94_RS11305	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU94_RS11305	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIU94_RS11340	COG5265	(ABC) transporter
FIU94_RS11355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU94_RS11370	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU94_RS11375	COG1160	GTP binding
FIU94_RS11385	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIU94_RS11395	COG1862	Preprotein translocase
FIU94_RS11400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU94_RS11405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIU94_RS11415	COG3737	Protein of unknown function (DUF498/DUF598)
FIU94_RS11420	COG4133	protoheme IX ABC transporter activity
FIU94_RS11425	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU94_RS11430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FIU94_RS11440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU94_RS11475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIU94_RS11520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FIU94_RS11525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FIU94_RS11525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FIU94_RS11535	COG0544	peptidyl-prolyl cis-trans isomerase activity
FIU94_RS11550	COG0318	PFAM AMP-dependent synthetase and ligase
FIU94_RS11565	COG0747	negative chemotaxis
FIU94_RS11575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU94_RS11580	COG4172	Belongs to the ABC transporter superfamily
FIU94_RS11590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FIU94_RS11595	COG3048	D-serine ammonia-lyase activity
FIU94_RS11605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU94_RS11610	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS11620	COG1234	tRNA 3'-trailer cleavage
FIU94_RS11625	COG0084	hydrolase, TatD family'
FIU94_RS11655	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FIU94_RS11660	COG1686	Belongs to the peptidase S11 family
FIU94_RS11725	COG1079	Belongs to the binding-protein-dependent transport system permease family
FIU94_RS11730	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU94_RS11785	COG1764	response to oxidative stress
FIU94_RS11790	COG0583	DNA-binding transcription factor activity
FIU94_RS11825	COG0747	negative chemotaxis
FIU94_RS11830	COG0601	transmembrane transport
FIU94_RS11835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU94_RS11840	COG4172	Belongs to the ABC transporter superfamily
FIU94_RS11880	COG3448	diguanylate cyclase activity
FIU94_RS11880	COG4175	Glycine betaine
FIU94_RS11895	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS11905	COG4335	DNA alkylation repair
FIU94_RS11910	COG3842	ATPase activity
FIU94_RS11925	COG2378	regulation of single-species biofilm formation
FIU94_RS11930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU94_RS11935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FIU94_RS11940	COG0805	protein transport
FIU94_RS11955	COG0739	heme binding
FIU94_RS11955	COG1388	LysM domain
FIU94_RS11960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FIU94_RS11965	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FIU94_RS11970	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS11985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FIU94_RS12010	COG5441	Belongs to the UPF0261 family
FIU94_RS12015	COG1012	belongs to the aldehyde dehydrogenase family
FIU94_RS12040	COG0174	glutamine synthetase
FIU94_RS12045	COG0519	Catalyzes the synthesis of GMP from XMP
FIU94_RS12045	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIU94_RS12055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU94_RS12090	COG0028	Belongs to the TPP enzyme family
FIU94_RS12120	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS12135	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS12145	COG3483	tryptophan 2,3-dioxygenase activity
FIU94_RS12170	COG0740	serine-type endopeptidase activity
FIU94_RS12175	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FIU94_RS12185	COG2264	protein methyltransferase activity
FIU94_RS12200	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FIU94_RS12205	COG0439	Biotin carboxylase
FIU94_RS12215	COG0318	PFAM AMP-dependent synthetase and ligase
FIU94_RS12220	COG2032	superoxide dismutase activity
FIU94_RS12225	COG0410	ABC transporter
FIU94_RS12250	COG3800	Transcriptional regulator
FIU94_RS12250	COG1396	sequence-specific DNA binding
FIU94_RS12255	COG0745	RESPONSE REGULATOR receiver
FIU94_RS12265	COG5002	protein histidine kinase activity
FIU94_RS12285	COG3750	Belongs to the UPF0335 family
FIU94_RS12295	COG0544	peptidyl-prolyl cis-trans isomerase activity
FIU94_RS12310	COG0739	heme binding
FIU94_RS12310	COG0741	lytic transglycosylase activity
FIU94_RS12310	COG1196	nuclear chromosome segregation
FIU94_RS12315	COG0488	(ABC) transporter
FIU94_RS12320	COG0359	binds to the 23S rRNA
FIU94_RS12325	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FIU94_RS12330	COG0360	Binds together with S18 to 16S ribosomal RNA
FIU94_RS12345	COG2353	YceI-like domain
FIU94_RS12350	COG3038	cytochrome b561
FIU94_RS12355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FIU94_RS12370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIU94_RS12385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIU94_RS12390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FIU94_RS12405	COG4695	Portal protein
FIU94_RS12490	COG0583	DNA-binding transcription factor activity
FIU94_RS12495	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU94_RS12505	COG0022	dehydrogenase e1 component
FIU94_RS12505	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIU94_RS12510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FIU94_RS12515	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FIU94_RS12525	COG0126	phosphoglycerate kinase activity
FIU94_RS12550	COG0739	heme binding
FIU94_RS12555	COG2833	Protein of unknown function (DUF455)
FIU94_RS12560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FIU94_RS12570	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FIU94_RS12575	COG2814	Major facilitator Superfamily
FIU94_RS12585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIU94_RS12600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FIU94_RS12620	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS12625	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FIU94_RS12645	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FIU94_RS12665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FIU94_RS12680	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FIU94_RS12685	COG1280	lysine exporter protein (LysE YggA)
FIU94_RS12690	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FIU94_RS12695	COG0259	pyridoxamine-phosphate oxidase activity
FIU94_RS12700	COG1278	Cold shock
FIU94_RS12720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FIU94_RS12755	COG0215	cysteine-tRNA ligase activity
FIU94_RS12760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIU94_RS12780	COG2814	Major facilitator Superfamily
FIU94_RS12810	COG0316	Belongs to the HesB IscA family
FIU94_RS12815	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FIU94_RS12820	COG0018	arginyl-trna synthetase
FIU94_RS12830	COG1472	Belongs to the glycosyl hydrolase 3 family
FIU94_RS12835	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FIU94_RS12840	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FIU94_RS12850	COG0717	Belongs to the dCTP deaminase family
FIU94_RS12865	COG0776	regulation of translation
FIU94_RS12870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIU94_RS12875	COG0416	fatty acid biosynthetic process
FIU94_RS12880	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FIU94_RS12900	COG0488	(ABC) transporter
FIU94_RS12925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FIU94_RS12930	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FIU94_RS12950	COG0148	phosphopyruvate hydratase activity
FIU94_RS12980	COG0513	Belongs to the DEAD box helicase family
FIU94_RS12995	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FIU94_RS13010	COG3956	TIGRFAM MazG family protein
FIU94_RS13015	COG1473	amidohydrolase
FIU94_RS13020	COG0010	Belongs to the arginase family
FIU94_RS13040	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FIU94_RS13045	COG2890	protein-(glutamine-N5) methyltransferase activity
FIU94_RS13065	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FIU94_RS13070	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FIU94_RS13080	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FIU94_RS13095	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIU94_RS13110	COG2095	MarC family integral membrane protein
FIU94_RS13115	COG0488	(ABC) transporter
FIU94_RS13120	COG0105	UTP biosynthetic process
FIU94_RS13135	COG0829	nickel cation binding
FIU94_RS13140	COG0831	urea catabolic process
FIU94_RS13150	COG0832	Belongs to the urease beta subunit family
FIU94_RS13155	COG0804	urea catabolic process
FIU94_RS13160	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FIU94_RS13165	COG0830	nickel cation binding
FIU94_RS13170	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FIU94_RS13180	COG1741	Belongs to the pirin family
FIU94_RS13220	COG2814	Major facilitator Superfamily
FIU94_RS13225	COG0156	8-amino-7-oxononanoate synthase activity
FIU94_RS13235	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FIU94_RS13250	COG0436	Aminotransferase
FIU94_RS13255	COG0860	N-Acetylmuramoyl-L-alanine amidase
FIU94_RS13260	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FIU94_RS13265	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FIU94_RS13295	COG0440	acetolactate synthase activity
FIU94_RS13300	COG0028	Belongs to the TPP enzyme family
FIU94_RS13305	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FIU94_RS13315	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU94_RS13320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FIU94_RS13330	COG1309	transcriptional regulator
FIU94_RS13335	COG2326	polyphosphate kinase activity
FIU94_RS13340	COG0596	Alpha beta hydrolase
FIU94_RS13345	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FIU94_RS13365	COG0697	spore germination
FIU94_RS13370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIU94_RS13370	COG0519	Catalyzes the synthesis of GMP from XMP
FIU94_RS13390	COG3909	cytochrome
FIU94_RS13395	COG2010	Cytochrome c
FIU94_RS13405	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FIU94_RS13410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FIU94_RS13415	COG2867	negative regulation of translational initiation
FIU94_RS13425	COG0004	ammonium transporteR
FIU94_RS13435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FIU94_RS13440	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FIU94_RS13440	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FIU94_RS13445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIU94_RS13450	COG3852	Histidine kinase
FIU94_RS13455	COG2204	response regulator
FIU94_RS13460	COG5000	phosphorelay sensor kinase activity
FIU94_RS13465	COG2204	response regulator
FIU94_RS13475	COG0569	domain protein
FIU94_RS13480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU94_RS13485	COG1923	regulation of RNA biosynthetic process
FIU94_RS13490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIU94_RS13510	COG2084	Dehydrogenase
FIU94_RS13540	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FIU94_RS13545	COG2814	Major facilitator Superfamily
FIU94_RS13575	COG4166	transmembrane transport
FIU94_RS13580	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS13595	COG2313	pseudouridylate synthase activity
FIU94_RS13615	COG0352	thiamine-phosphate diphosphorylase activity
FIU94_RS13625	COG1612	heme a metabolic process
FIU94_RS13630	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FIU94_RS13640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIU94_RS13645	COG5425	PFAM Usg family protein
FIU94_RS13655	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FIU94_RS13665	COG0166	Belongs to the GPI family
FIU94_RS13680	COG0318	PFAM AMP-dependent synthetase and ligase
FIU94_RS13700	COG2226	methyltransferase
FIU94_RS13710	COG0516	GMP reductase activity
FIU94_RS13710	COG0517	IMP dehydrogenase activity
FIU94_RS13730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FIU94_RS13735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FIU94_RS13745	COG1217	gtp-binding protein TYPA
FIU94_RS13750	COG2076	Multidrug Resistance protein
FIU94_RS13755	COG1522	sequence-specific DNA binding
FIU94_RS13765	COG0121	glutamine amidotransferase
FIU94_RS13770	COG0538	isocitrate dehydrogenase activity
FIU94_RS13785	COG2945	thiolester hydrolase activity
FIU94_RS13790	COG1959	2 iron, 2 sulfur cluster binding
FIU94_RS13800	COG0719	Fe-S assembly protein
FIU94_RS13805	COG0396	ATPase activity
FIU94_RS13810	COG0719	Fe-S assembly protein
FIU94_RS13825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIU94_RS13845	COG0655	NAD(P)H dehydrogenase (quinone) activity
FIU94_RS13850	COG2308	Evidence 4 Homologs of previously reported genes of
FIU94_RS13905	COG1129	ABC transporter
FIU94_RS13920	COG1846	Transcriptional regulator
FIU94_RS13965	COG2205	protein histidine kinase activity
FIU94_RS13965	COG0784	Response regulator, receiver
FIU94_RS13965	COG2198	Histidine kinase
FIU94_RS13975	COG2201	protein-glutamate methylesterase activity
FIU94_RS13980	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FIU94_RS13990	COG0745	RESPONSE REGULATOR receiver
FIU94_RS13995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FIU94_RS14000	COG0835	chemotaxis
FIU94_RS14010	COG0643	Histidine kinase
FIU94_RS14010	COG0784	Response regulator, receiver
FIU94_RS14010	COG2198	Histidine kinase
FIU94_RS14025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FIU94_RS14035	COG0248	Ppx GppA phosphatase
FIU94_RS14040	COG5507	3-demethylubiquinone-9 3-methyltransferase
FIU94_RS14045	COG1733	regulation of RNA biosynthetic process
FIU94_RS14050	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FIU94_RS14075	COG3743	rRNA binding
FIU94_RS14075	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FIU94_RS14080	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FIU94_RS14090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FIU94_RS14095	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FIU94_RS14100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FIU94_RS14130	COG0052	Belongs to the universal ribosomal protein uS2 family
FIU94_RS14135	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FIU94_RS14140	COG2771	luxR family
FIU94_RS14145	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FIU94_RS14150	COG0745	RESPONSE REGULATOR receiver
FIU94_RS14160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU94_RS14170	COG0573	inorganic phosphate transmembrane transporter activity
FIU94_RS14180	COG5002	protein histidine kinase activity
FIU94_RS14190	COG0194	GDP metabolic process
FIU94_RS14195	COG1561	YicC-like family, N-terminal region
FIU94_RS14205	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FIU94_RS14215	COG2133	pyrroloquinoline quinone binding
FIU94_RS14255	COG0433	COG0433 Predicted ATPase
FIU94_RS14275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIU94_RS14280	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU94_RS14285	COG2989	Protein conserved in bacteria
FIU94_RS14300	COG2197	response regulator
FIU94_RS14305	COG0683	leucine binding
FIU94_RS14330	COG0596	Alpha beta hydrolase
FIU94_RS14340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FIU94_RS14345	COG3264	Mechanosensitive ion channel
FIU94_RS14345	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FIU94_RS14355	COG0494	nUDIX hydrolase
FIU94_RS14365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIU94_RS14370	COG0415	Belongs to the DNA photolyase family
FIU94_RS14375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FIU94_RS14380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU94_RS14385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIU94_RS14390	COG0537	adenosine 5'-monophosphoramidase activity
FIU94_RS14400	COG0604	alcohol dehydrogenase
FIU94_RS14425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FIU94_RS14445	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FIU94_RS14450	COG2226	methyltransferase
FIU94_RS14455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU94_RS14460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FIU94_RS14475	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FIU94_RS14480	COG0745	RESPONSE REGULATOR receiver
FIU94_RS14490	COG0482	sulfurtransferase activity
FIU94_RS14495	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU94_RS14500	COG3494	Protein of unknown function (DUF1009)
FIU94_RS14505	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIU94_RS14510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FIU94_RS14520	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU94_RS14525	COG0750	zinc metalloprotease
FIU94_RS14535	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FIU94_RS14540	COG0233	cytoplasmic translational termination
FIU94_RS14545	COG3920	Histidine kinase
FIU94_RS14550	COG0528	UMP kinase activity
FIU94_RS14555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FIU94_RS14565	COG0601	transmembrane transport
FIU94_RS14570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU94_RS14585	COG0741	lytic transglycosylase activity
FIU94_RS14590	COG0629	single-stranded DNA binding
FIU94_RS14595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FIU94_RS14600	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FIU94_RS14610	COG4974	Belongs to the 'phage' integrase family
FIU94_RS14615	COG4536	flavin adenine dinucleotide binding
FIU94_RS14620	COG1183	phosphatidylcholine synthase activity
FIU94_RS14645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIU94_RS14665	COG1238	metal cluster binding
FIU94_RS14670	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FIU94_RS14680	COG0010	Belongs to the arginase family
FIU94_RS14685	COG2423	ornithine cyclodeaminase activity
FIU94_RS14690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU94_RS14700	COG0542	response to heat
FIU94_RS14720	COG1764	response to oxidative stress
FIU94_RS14725	COG2323	membrane
FIU94_RS14740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIU94_RS14775	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FIU94_RS14785	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FIU94_RS14805	COG3437	response regulator, receiver
FIU94_RS14805	COG4999	Histidine kinase
FIU94_RS14805	COG3850	Histidine kinase
FIU94_RS14805	COG2205	protein histidine kinase activity
FIU94_RS14810	COG2059	Chromate
FIU94_RS14840	COG0114	fumarate hydratase activity
FIU94_RS14860	COG3588	fructose-bisphosphate aldolase
FIU94_RS14875	COG0785	Cytochrome C biogenesis protein
FIU94_RS14880	COG0425	Belongs to the sulfur carrier protein TusA family
FIU94_RS14885	COG1530	ribonuclease E activity
FIU94_RS14895	COG2204	response regulator
FIU94_RS14905	COG0047	phosphoribosylformylglycinamidine synthase activity
FIU94_RS14915	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIU94_RS14920	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FIU94_RS14935	COG0646	methionine synthase
FIU94_RS14935	COG1410	methionine synthase
FIU94_RS14945	COG5012	cobalamin binding
FIU94_RS14965	COG2166	iron-sulfur cluster assembly
FIU94_RS14975	COG0251	oxidation-reduction process
FIU94_RS14980	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FIU94_RS14985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FIU94_RS14990	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FIU94_RS15005	COG0798	PFAM Bile acid sodium symporter
FIU94_RS15040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FIU94_RS15070	COG0406	alpha-ribazole phosphatase activity
FIU94_RS15075	COG0406	alpha-ribazole phosphatase activity
FIU94_RS15090	COG0776	regulation of translation
FIU94_RS15095	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIU94_RS15100	COG1902	pentaerythritol trinitrate reductase activity
FIU94_RS15105	COG0343	queuine tRNA-ribosyltransferase activity
FIU94_RS15125	COG0189	ligase activity
FIU94_RS15125	COG4067	protein conserved in archaea
FIU94_RS15130	COG2151	metal-sulfur cluster biosynthetic enzyme
FIU94_RS15150	COG0149	triose-phosphate isomerase activity
FIU94_RS15155	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU94_RS15160	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU94_RS15165	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU94_RS15180	COG2124	cytochrome p450
FIU94_RS15185	COG1522	sequence-specific DNA binding
FIU94_RS15190	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FIU94_RS15190	COG1648	precorrin-2 dehydrogenase activity
FIU94_RS15200	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FIU94_RS15205	COG0175	sulfate reduction
FIU94_RS15225	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FIU94_RS15230	COG2885	chlorophyll binding
FIU94_RS15255	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FIU94_RS15265	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FIU94_RS15280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FIU94_RS15285	COG2354	Protein conserved in bacteria
FIU94_RS15305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FIU94_RS15310	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FIU94_RS15320	COG0315	cyclic pyranopterin monophosphate synthase activity
FIU94_RS15325	COG0303	'Molybdopterin
FIU94_RS15330	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FIU94_RS15335	COG2333	competence protein COMEC
FIU94_RS15335	COG0658	competence protein
FIU94_RS15340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIU94_RS15345	COG0372	Belongs to the citrate synthase family
FIU94_RS15355	COG1024	Enoyl-CoA hydratase
FIU94_RS15360	COG3088	subunit of a heme lyase
FIU94_RS15365	COG1138	Cytochrome C-type biogenesis protein
FIU94_RS15380	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FIU94_RS15385	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FIU94_RS15390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FIU94_RS15410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIU94_RS15455	COG0418	dihydroorotase activity
FIU94_RS15460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FIU94_RS15465	COG0305	Participates in initiation and elongation during chromosome replication
FIU94_RS15485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FIU94_RS15500	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FIU94_RS15510	COG0513	Belongs to the DEAD box helicase family
FIU94_RS15525	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FIU94_RS15535	COG1007	ATP synthesis coupled electron transport
FIU94_RS15550	COG0713	ATP synthesis coupled electron transport
FIU94_RS15565	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU94_RS15570	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FIU94_RS15615	COG3743	rRNA binding
FIU94_RS15615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FIU94_RS15625	COG0649	NAD binding
FIU94_RS15630	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU94_RS15635	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIU94_RS15645	COG1090	epimerase
FIU94_RS15655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FIU94_RS15680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU94_RS15695	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS15705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIU94_RS15710	COG0546	phosphoglycolate phosphatase activity
FIU94_RS15715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FIU94_RS15740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FIU94_RS15745	COG1519	Transferase
FIU94_RS15750	COG0438	transferase activity, transferring glycosyl groups
FIU94_RS15755	COG1473	amidohydrolase
FIU94_RS15760	COG1473	amidohydrolase
FIU94_RS15765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU94_RS15775	COG4172	Belongs to the ABC transporter superfamily
FIU94_RS15785	COG0601	transmembrane transport
FIU94_RS15790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU94_RS15810	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FIU94_RS15825	COG1943	Transposase
FIU94_RS15850	COG0308	aminopeptidase N
FIU94_RS15855	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS15875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIU94_RS15895	COG0484	heat shock protein binding
FIU94_RS15935	COG0006	proline dipeptidase activity
FIU94_RS15955	COG0038	chloride channel
FIU94_RS15965	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIU94_RS15970	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FIU94_RS15975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FIU94_RS15980	COG0849	cell division
FIU94_RS15985	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FIU94_RS15990	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIU94_RS15995	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FIU94_RS16015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIU94_RS16020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FIU94_RS16030	COG5285	phytanoyl-CoA dioxygenase
FIU94_RS16035	COG2081	HI0933 family
FIU94_RS16040	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FIU94_RS16045	COG2066	Belongs to the glutaminase family
FIU94_RS16050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FIU94_RS16060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIU94_RS16065	COG0768	penicillin binding
FIU94_RS16075	COG0275	rRNA processing
FIU94_RS16080	COG2001	Belongs to the MraZ family
FIU94_RS16090	COG0489	protein tyrosine kinase activity
FIU94_RS16100	COG0210	DNA helicase
FIU94_RS16110	COG1304	FMN binding
FIU94_RS16115	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FIU94_RS16120	COG0346	lactoylglutathione lyase activity
FIU94_RS16125	COG1629	transport
FIU94_RS16130	COG3720	iron ion transport
FIU94_RS16135	COG4558	Periplasmic binding protein
FIU94_RS16140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIU94_RS16145	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FIU94_RS16185	COG1610	YqeY-like protein
FIU94_RS16190	COG0505	Belongs to the CarA family
FIU94_RS16195	COG1215	transferase activity, transferring glycosyl groups
FIU94_RS16200	COG1802	Transcriptional regulator
FIU94_RS16210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU94_RS16220	COG1522	sequence-specific DNA binding
FIU94_RS16230	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FIU94_RS16240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FIU94_RS16245	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIU94_RS16250	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIU94_RS16260	COG0574	Belongs to the PEP-utilizing enzyme family
FIU94_RS16260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIU94_RS16265	COG0751	glycine-tRNA ligase activity
FIU94_RS16280	COG0752	glycyl-tRNA synthetase alpha subunit
FIU94_RS16295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIU94_RS16305	COG1469	GTP cyclohydrolase I activity
FIU94_RS16315	COG0625	glutathione transferase activity
FIU94_RS16330	COG1285	pathogenesis
FIU94_RS16335	COG0552	protein localization to endoplasmic reticulum
FIU94_RS16340	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FIU94_RS16365	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FIU94_RS16370	COG3239	Fatty acid desaturase
FIU94_RS16385	COG1570	exodeoxyribonuclease VII activity
FIU94_RS16390	COG0151	Belongs to the GarS family
FIU94_RS16415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FIU94_RS16425	COG0330	HflC and HflK could
FIU94_RS16430	COG0330	HflC and HflK could
FIU94_RS16440	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FIU94_RS16450	COG1760	l-serine dehydratase
FIU94_RS16455	COG1278	Cold shock
FIU94_RS16470	COG1741	Belongs to the pirin family
FIU94_RS16505	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FIU94_RS16520	COG4983	Phage plasmid primase, P4 family domain protein
FIU94_RS16540	COG0582	viral genome integration into host DNA
FIU94_RS16545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIU94_RS16550	COG3206	protein involved in exopolysaccharide biosynthesis
FIU94_RS16550	COG0489	protein tyrosine kinase activity
FIU94_RS16565	COG0297	glycogen (starch) synthase activity
FIU94_RS16565	COG0438	transferase activity, transferring glycosyl groups
FIU94_RS16590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FIU94_RS16640	COG0546	phosphoglycolate phosphatase activity
FIU94_RS16670	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FIU94_RS16700	COG0504	CTP synthase activity
FIU94_RS16705	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FIU94_RS16740	COG4215	(ABC) transporter
FIU94_RS16745	COG4160	amino acid transport
FIU94_RS16750	COG0174	glutamine synthetase
FIU94_RS16755	COG0519	Catalyzes the synthesis of GMP from XMP
FIU94_RS16755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FIU94_RS16760	COG0174	glutamine synthetase
FIU94_RS16765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIU94_RS16770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIU94_RS16785	COG3243	poly(R)-hydroxyalkanoic acid synthase
FIU94_RS16795	COG0183	Belongs to the thiolase family
FIU94_RS16800	COG2030	dehydratase
FIU94_RS16805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU94_RS16820	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS16825	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS16840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIU94_RS16850	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS16860	COG1024	Enoyl-CoA hydratase
FIU94_RS16870	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS16890	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIU94_RS16905	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FIU94_RS16910	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS16920	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS16935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU94_RS16940	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FIU94_RS16950	COG1024	Enoyl-CoA hydratase
FIU94_RS16955	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS16960	COG1902	pentaerythritol trinitrate reductase activity
FIU94_RS16960	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIU94_RS16965	COG0318	PFAM AMP-dependent synthetase and ligase
FIU94_RS16970	COG0625	glutathione transferase activity
FIU94_RS16975	COG2259	Doxx family
FIU94_RS16985	COG0519	Catalyzes the synthesis of GMP from XMP
FIU94_RS17005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIU94_RS17010	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS17015	COG1309	transcriptional regulator
FIU94_RS17035	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS17040	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS17045	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS17050	COG1024	Enoyl-CoA hydratase
FIU94_RS17065	COG0511	ligase activity, forming carbon-carbon bonds
FIU94_RS17065	COG5016	pyruvate
FIU94_RS17085	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS17090	COG1309	transcriptional regulator
FIU94_RS17095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FIU94_RS17100	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FIU94_RS17110	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS17115	COG1268	BioY protein
FIU94_RS17120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU94_RS17135	COG0251	oxidation-reduction process
FIU94_RS17155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU94_RS17235	COG0741	lytic transglycosylase activity
FIU94_RS17235	COG1196	nuclear chromosome segregation
FIU94_RS17235	COG0739	heme binding
FIU94_RS17250	COG3451	type IV secretory pathway VirB4
FIU94_RS17260	COG0741	lytic transglycosylase activity
FIU94_RS17260	COG0739	heme binding
FIU94_RS17260	COG1196	nuclear chromosome segregation
FIU94_RS17280	COG3736	Type IV secretory pathway, component VirB8
FIU94_RS17290	COG2948	multi-organism process
FIU94_RS17295	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FIU94_RS17320	COG0702	epimerase
FIU94_RS17340	COG3177	Filamentation induced by cAMP protein fic
FIU94_RS17440	COG0785	Cytochrome C biogenesis protein
FIU94_RS17465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU94_RS17470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FIU94_RS17485	COG2132	Multicopper oxidase
FIU94_RS17495	COG1230	cation diffusion facilitator family transporter
FIU94_RS17510	COG0789	Transcriptional regulator
FIU94_RS17515	COG1999	signal sequence binding
FIU94_RS17525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FIU94_RS17525	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FIU94_RS17535	COG1999	signal sequence binding
FIU94_RS17575	COG3505	Type IV secretory pathway VirD4
FIU94_RS17580	COG3843	relaxase mobilization nuclease domain protein
FIU94_RS17605	COG0433	COG0433 Predicted ATPase
FIU94_RS17660	COG1414	Transcriptional regulator
FIU94_RS17670	COG1192	Involved in chromosome partitioning
FIU94_RS17700	COG2813	Specifically methylates the guanine in position
FIU94_RS17710	COG3609	addiction module antidote protein, CC2985 family
FIU94_RS17740	COG1475	DNA binding
FIU94_RS17770	COG3177	Filamentation induced by cAMP protein fic
FIU94_RS17790	COG0702	epimerase
FIU94_RS17800	COG3384	dioxygenase
FIU94_RS17810	COG1733	regulation of RNA biosynthetic process
FIU94_RS17815	COG1309	transcriptional regulator
FIU94_RS17850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU94_RS17855	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS17860	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS17900	COG1024	Enoyl-CoA hydratase
FIU94_RS17905	COG1024	Enoyl-CoA hydratase
FIU94_RS17925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU94_RS17960	COG0583	DNA-binding transcription factor activity
FIU94_RS17985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU94_RS18000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU94_RS18005	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FIU94_RS18010	COG0156	8-amino-7-oxononanoate synthase activity
FIU94_RS18050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU94_RS18080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FIU94_RS18085	COG4597	amino acid ABC transporter
FIU94_RS18090	COG0765	amino acid transport
FIU94_RS18095	COG1126	abc transporter atp-binding protein
FIU94_RS18100	COG3119	arylsulfatase activity
FIU94_RS18105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIU94_RS18115	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS18125	COG1012	belongs to the aldehyde dehydrogenase family
FIU94_RS18130	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS18135	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS18140	COG3938	Belongs to the proline racemase family
FIU94_RS18155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU94_RS18180	COG2909	trisaccharide binding
FIU94_RS18195	COG0408	coproporphyrinogen oxidase activity
FIU94_RS18200	COG4608	Belongs to the ABC transporter superfamily
FIU94_RS18205	COG0444	Belongs to the ABC transporter superfamily
FIU94_RS18215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU94_RS18225	COG0747	negative chemotaxis
FIU94_RS18245	COG0006	proline dipeptidase activity
FIU94_RS18250	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU94_RS18255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIU94_RS18260	COG1414	Transcriptional regulator
FIU94_RS18270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FIU94_RS18280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIU94_RS18310	COG1192	Involved in chromosome partitioning
FIU94_RS18315	COG1475	DNA binding
FIU94_RS18320	COG0463	Glycosyl transferase, family 2
FIU94_RS18335	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FIU94_RS18350	COG3568	Endonuclease Exonuclease Phosphatase
FIU94_RS18365	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FIU94_RS18370	COG0511	ligase activity, forming carbon-carbon bonds
FIU94_RS18370	COG5016	pyruvate
FIU94_RS18385	COG1984	allophanate hydrolase subunit 2
FIU94_RS18390	COG1879	ABC-type sugar transport system periplasmic component
FIU94_RS18400	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU94_RS18420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FIU94_RS18425	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
FIU94_RS18435	COG0535	radical SAM domain protein
FIU94_RS18440	COG2304	oxidoreductase activity
FIU94_RS18500	COG1116	anion transmembrane transporter activity
FIU94_RS18560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU94_RS18575	COG1414	Transcriptional regulator
FIU94_RS18580	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU94_RS18590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIU94_RS18615	COG4948	Mandelate Racemase Muconate Lactonizing
FIU94_RS18640	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS18645	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS18690	COG2801	Transposase and inactivated derivatives
FIU94_RS18705	COG0436	Aminotransferase
FIU94_RS18745	COG1053	succinate dehydrogenase
FIU94_RS18755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FIU94_RS18760	COG4948	Mandelate Racemase Muconate Lactonizing
FIU94_RS18805	COG0811	peptide transport
FIU94_RS18815	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS18920	COG1192	Involved in chromosome partitioning
FIU94_RS18925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FIU94_RS18955	COG3034	peptidoglycan biosynthetic process
FIU94_RS18965	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FIU94_RS18980	COG1321	iron dependent repressor
FIU94_RS18995	COG2366	antibiotic biosynthetic process
FIU94_RS19000	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIU94_RS19005	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FIU94_RS19025	COG1999	signal sequence binding
FIU94_RS19050	COG0789	Transcriptional regulator
FIU94_RS19055	COG1742	UPF0060 membrane protein
FIU94_RS19060	COG0785	Cytochrome C biogenesis protein
FIU94_RS19070	COG1230	cation diffusion facilitator family transporter
FIU94_RS19105	COG0456	acetyltransferase
FIU94_RS19105	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FIU94_RS19135	COG2226	methyltransferase
FIU94_RS19150	COG2169	Transcriptional regulator
FIU94_RS19150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FIU94_RS19160	COG1280	lysine exporter protein (LysE YggA)
FIU94_RS19170	COG2318	DinB family
FIU94_RS19210	COG0741	lytic transglycosylase activity
FIU94_RS19210	COG1196	nuclear chromosome segregation
FIU94_RS19210	COG0739	heme binding
FIU94_RS19230	COG0739	heme binding
FIU94_RS19230	COG0741	lytic transglycosylase activity
FIU94_RS19230	COG1196	nuclear chromosome segregation
FIU94_RS19255	COG4962	Type ii secretion system protein e
FIU94_RS19300	COG0419	ATPase involved in DNA repair
FIU94_RS19350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FIU94_RS19380	COG3550	peptidyl-serine autophosphorylation
FIU94_RS19385	COG2115	Belongs to the xylose isomerase family
FIU94_RS19395	COG0673	inositol 2-dehydrogenase activity
FIU94_RS19400	COG1129	ABC transporter
FIU94_RS19405	COG1172	Belongs to the binding-protein-dependent transport system permease family
FIU94_RS19430	COG0668	transmembrane transport
FIU94_RS19470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FIU94_RS19480	COG3971	2-oxopent-4-enoate hydratase activity
FIU94_RS19505	COG1024	Enoyl-CoA hydratase
FIU94_RS19510	COG2301	Belongs to the HpcH HpaI aldolase family
FIU94_RS19525	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS19540	COG0427	acetyl-CoA hydrolase
FIU94_RS19545	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FIU94_RS19555	COG1309	transcriptional regulator
FIU94_RS19585	COG1024	Enoyl-CoA hydratase
FIU94_RS19590	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS19600	COG1473	amidohydrolase
FIU94_RS19605	COG0657	acetylesterase activity
FIU94_RS19610	COG0318	PFAM AMP-dependent synthetase and ligase
FIU94_RS19615	COG1024	Enoyl-CoA hydratase
FIU94_RS19635	COG3842	ATPase activity
FIU94_RS19640	COG1309	transcriptional regulator
FIU94_RS19645	COG0395	ABC-type sugar transport system, permease component
FIU94_RS19650	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIU94_RS19655	COG3842	ATPase activity
FIU94_RS19660	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIU94_RS19665	COG3842	ATPase activity
FIU94_RS19670	COG0395	ABC-type sugar transport system, permease component
FIU94_RS19675	COG1175	transmembrane transport
FIU94_RS19710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIU94_RS19715	COG0444	Belongs to the ABC transporter superfamily
FIU94_RS19720	COG4608	Belongs to the ABC transporter superfamily
FIU94_RS19725	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FIU94_RS19740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIU94_RS19750	COG1192	Involved in chromosome partitioning
FIU94_RS19795	COG0277	FAD linked oxidase domain protein
FIU94_RS19800	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU94_RS19810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU94_RS19825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FIU94_RS19830	COG1121	(ABC) transporter
FIU94_RS19835	COG0735	belongs to the Fur family
FIU94_RS19845	COG1609	Transcriptional regulator
FIU94_RS19855	COG0697	spore germination
FIU94_RS19870	COG3474	cytochrome
FIU94_RS19890	COG1129	ABC transporter
FIU94_RS19905	COG0251	oxidation-reduction process
FIU94_RS19915	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIU94_RS19920	COG1846	Transcriptional regulator
FIU94_RS19940	COG3842	ATPase activity
FIU94_RS19945	COG3842	ATPase activity
FIU94_RS19950	COG1175	transmembrane transport
FIU94_RS19955	COG0395	ABC-type sugar transport system, permease component
FIU94_RS19975	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIU94_RS19980	COG1454	alcohol dehydrogenase
FIU94_RS19985	COG4993	Dehydrogenase
FIU94_RS19995	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FIU94_RS20005	COG0352	thiamine-phosphate diphosphorylase activity
FIU94_RS20020	COG1051	belongs to the nudix hydrolase family
FIU94_RS20035	COG0583	DNA-binding transcription factor activity
FIU94_RS20040	COG0697	spore germination
FIU94_RS20045	COG0318	PFAM AMP-dependent synthetase and ligase
FIU94_RS20065	COG0559	Belongs to the binding-protein-dependent transport system permease family
FIU94_RS20075	COG2268	Band 7 protein
FIU94_RS20100	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU94_RS20110	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FIU94_RS20120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FIU94_RS20130	COG0181	hydroxymethylbilane synthase activity
FIU94_RS20135	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FIU94_RS20180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FIU94_RS20210	COG1846	Transcriptional regulator
FIU94_RS20240	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIU94_RS20245	COG3473	Maleate cis-trans isomerase
FIU94_RS20265	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU94_RS20285	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS20290	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FIU94_RS20315	COG4638	Rieske (2fe-2S)
FIU94_RS20325	COG1192	Involved in chromosome partitioning
FIU94_RS20330	COG1475	DNA binding
FIU94_RS20335	COG1414	Transcriptional regulator
FIU94_RS20370	COG4453	Protein conserved in bacteria
FIU94_RS20375	COG3153	acetyltransferase
FIU94_RS20380	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FIU94_RS20385	COG0210	DNA helicase
FIU94_RS20405	COG3843	relaxase mobilization nuclease domain protein
FIU94_RS20415	COG0583	DNA-binding transcription factor activity
FIU94_RS20420	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FIU94_RS20430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FIU94_RS20435	COG1028	Short-chain dehydrogenase reductase Sdr
FIU94_RS20440	COG3958	Transketolase
FIU94_RS20445	COG3959	Transketolase, thiamine diphosphate binding domain
FIU94_RS20450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FIU94_RS20475	COG3831	ATPase activity
FIU94_RS20485	COG1204	response to ionizing radiation
FIU94_RS20495	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FIU94_RS20500	COG2948	multi-organism process
FIU94_RS20510	COG3736	Type IV secretory pathway, component VirB8
FIU94_RS20530	COG0741	lytic transglycosylase activity
FIU94_RS20530	COG1196	nuclear chromosome segregation
FIU94_RS20530	COG0739	heme binding
FIU94_RS20540	COG3451	type IV secretory pathway VirB4
FIU94_RS20555	COG0739	heme binding
FIU94_RS20555	COG1196	nuclear chromosome segregation
FIU94_RS20555	COG0741	lytic transglycosylase activity
FIU94_RS20580	COG0183	Belongs to the thiolase family
FIU94_RS20615	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIU94_RS20615	COG1024	Enoyl-CoA hydratase
FIU94_RS20630	COG1960	acyl-CoA dehydrogenase activity
FIU94_RS20635	COG1454	alcohol dehydrogenase
FIU94_RS20640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FIU94_RS20660	COG1475	DNA binding
FIU94_RS20690	COG3609	addiction module antidote protein, CC2985 family
FIU94_RS20725	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FIU94_RS20745	COG4227	nucleotidyltransferase activity
FIU94_RS20770	COG3505	Type IV secretory pathway VirD4