locus-tag class description SIRE_RS00020 PF01329 Pterin 4 alpha carbinolamine dehydratase SIRE_RS00060 PF01145 SPFH domain / Band 7 family SIRE_RS00100 PF03190 Protein of unknown function, DUF255 SIRE_RS00110 PF03070 TENA/THI-4/PQQC family SIRE_RS00120 PF01939 Endonuclease NucS SIRE_RS00145 PF02277 Phosphoribosyltransferase SIRE_RS00155 PF00266 Aminotransferase class-V SIRE_RS00160 PF00501 AMP-binding enzyme SIRE_RS00160 PF16177 Acetyl-coenzyme A synthetase N-terminus SIRE_RS00160 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS00170 PF01513 ATP-NAD kinase SIRE_RS00175 PF07690 Major Facilitator Superfamily SIRE_RS00185 PF07992 Pyridine nucleotide-disulphide oxidoreductase SIRE_RS00195 PF01985 CRS1 / YhbY (CRM) domain SIRE_RS00240 PF00085 Thioredoxin SIRE_RS00255 PF00300 Histidine phosphatase superfamily (branch 1) SIRE_RS00275 PF01156 Inosine-uridine preferring nucleoside hydrolase SIRE_RS00295 PF16916 Dimerisation domain of Zinc Transporter SIRE_RS00295 PF01545 Cation efflux family SIRE_RS00305 PF00005 ABC transporter SIRE_RS00325 PF03853 YjeF-related protein N-terminus SIRE_RS00325 PF01256 Carbohydrate kinase SIRE_RS00330 PF00578 AhpC/TSA family SIRE_RS00335 PF14010 Phosphoenolpyruvate carboxylase SIRE_RS00355 PF00561 alpha/beta hydrolase fold SIRE_RS00370 PF02310 B12 binding domain SIRE_RS00400 PF01925 Sulfite exporter TauE/SafE SIRE_RS00410 PF00701 Dihydrodipicolinate synthetase family SIRE_RS00415 PF03167 Uracil DNA glycosylase superfamily SIRE_RS00440 PF00293 NUDIX domain SIRE_RS00440 PF13344 Haloacid dehalogenase-like hydrolase SIRE_RS00445 PF09190 DALR domain SIRE_RS00445 PF01406 tRNA synthetases class I (C) catalytic domain SIRE_RS00450 PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain SIRE_RS00450 PF01380 SIS domain SIRE_RS00460 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SIRE_RS00460 PF07992 Pyridine nucleotide-disulphide oxidoreductase SIRE_RS00470 PF09378 HAS barrel domain SIRE_RS00470 PF01935 Helicase HerA, central domain SIRE_RS00480 PF03061 Thioesterase superfamily SIRE_RS00495 PF03372 Endonuclease/Exonuclease/phosphatase family SIRE_RS00500 PF00069 Protein kinase domain SIRE_RS00500 PF03793 PASTA domain SIRE_RS00520 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SIRE_RS00530 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SIRE_RS00535 PF14824 Sirohaem biosynthesis protein central SIRE_RS00535 PF10414 Sirohaem synthase dimerisation region SIRE_RS00535 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SIRE_RS00540 PF05175 Methyltransferase small domain SIRE_RS00545 PF01888 CbiD SIRE_RS00550 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SIRE_RS00550 PF01077 Nitrite and sulphite reductase 4Fe-4S domain SIRE_RS00555 PF02570 Precorrin-8X methylmutase SIRE_RS00575 PF04055 Radical SAM superfamily SIRE_RS00575 PF13186 Iron-sulfur cluster-binding domain SIRE_RS00580 PF00753 Metallo-beta-lactamase superfamily SIRE_RS00590 PF00437 Type II/IV secretion system protein SIRE_RS00670 PF00107 Zinc-binding dehydrogenase SIRE_RS00670 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS00700 PF00156 Phosphoribosyl transferase domain SIRE_RS00705 PF01048 Phosphorylase superfamily SIRE_RS00715 PF00348 Polyprenyl synthetase SIRE_RS00720 PF08443 RimK-like ATP-grasp domain SIRE_RS00740 PF01112 Asparaginase SIRE_RS00760 PF01134 Glucose inhibited division protein A SIRE_RS00775 PF13344 Haloacid dehalogenase-like hydrolase SIRE_RS00780 PF02910 Fumarate reductase flavoprotein C-term SIRE_RS00780 PF00890 FAD binding domain SIRE_RS00785 PF13183 4Fe-4S dicluster domain SIRE_RS00785 PF13085 2Fe-2S iron-sulfur cluster binding domain SIRE_RS00800 PF00092 von Willebrand factor type A domain SIRE_RS00805 PF17868 AAA lid domain SIRE_RS00805 PF12592 Protein of unknown function (DUF3763) SIRE_RS00805 PF07728 AAA domain (dynein-related subfamily) SIRE_RS00830 PF08544 GHMP kinases C terminal SIRE_RS00830 PF00288 GHMP kinases N terminal domain SIRE_RS00835 PF01053 Cys/Met metabolism PLP-dependent enzyme SIRE_RS00875 PF00108 Thiolase, N-terminal domain SIRE_RS00875 PF02803 Thiolase, C-terminal domain SIRE_RS00880 PF01938 TRAM domain SIRE_RS00880 PF04055 Radical SAM superfamily SIRE_RS00880 PF00919 Uncharacterized protein family UPF0004 SIRE_RS00900 PF01351 Ribonuclease HII SIRE_RS00915 PF00437 Type II/IV secretion system protein SIRE_RS00920 PF03552 Cellulose synthase SIRE_RS00920 PF07238 PilZ domain SIRE_RS00920 PF00535 Glycosyl transferase family 2 SIRE_RS00925 PF00719 Inorganic pyrophosphatase SIRE_RS00935 PF08543 Phosphomethylpyrimidine kinase SIRE_RS00940 PF02391 MoaE protein SIRE_RS00965 PF02548 Ketopantoate hydroxymethyltransferase SIRE_RS00975 PF00005 ABC transporter SIRE_RS01005 PF08502 LeuA allosteric (dimerisation) domain SIRE_RS01005 PF00682 HMGL-like SIRE_RS01035 PF01242 6-pyruvoyl tetrahydropterin synthase SIRE_RS01050 PF07992 Pyridine nucleotide-disulphide oxidoreductase SIRE_RS01055 PF00459 Inositol monophosphatase family SIRE_RS01060 PF06480 FtsH Extracellular SIRE_RS01060 PF01434 Peptidase family M41 SIRE_RS01060 PF17862 AAA+ lid domain SIRE_RS01060 PF00004 ATPase family associated with various cellular activities (AAA) SIRE_RS01075 PF00156 Phosphoribosyl transferase domain SIRE_RS01080 PF02310 B12 binding domain SIRE_RS01080 PF01642 Methylmalonyl-CoA mutase SIRE_RS01090 PF00011 Hsp20/alpha crystallin family SIRE_RS01100 PF09106 Elongation factor SelB, winged helix SIRE_RS01100 PF09105 Elongation factor SelB, winged helix SIRE_RS01100 PF03144 Elongation factor Tu domain 2 SIRE_RS01100 PF00009 Elongation factor Tu GTP binding domain SIRE_RS01100 PF09107 Elongation factor SelB, winged helix SIRE_RS01115 PF00132 Bacterial transferase hexapeptide (six repeats) SIRE_RS01115 PF12804 MobA-like NTP transferase domain SIRE_RS01120 PF00111 2Fe-2S iron-sulfur cluster binding domain SIRE_RS01120 PF01799 [2Fe-2S] binding domain SIRE_RS01125 PF03450 CO dehydrogenase flavoprotein C-terminal domain SIRE_RS01125 PF00941 FAD binding domain in molybdopterin dehydrogenase SIRE_RS01130 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SIRE_RS01150 PF01979 Amidohydrolase family SIRE_RS01160 PF00120 Glutamine synthetase, catalytic domain SIRE_RS01165 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS01165 PF00107 Zinc-binding dehydrogenase SIRE_RS01175 PF01137 RNA 3'-terminal phosphate cyclase SIRE_RS01175 PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain SIRE_RS01185 PF11799 impB/mucB/samB family C-terminal domain SIRE_RS01185 PF00817 impB/mucB/samB family SIRE_RS01190 PF00294 pfkB family carbohydrate kinase SIRE_RS01195 PF17862 AAA+ lid domain SIRE_RS01195 PF00004 ATPase family associated with various cellular activities (AAA) SIRE_RS01195 PF06480 FtsH Extracellular SIRE_RS01195 PF01434 Peptidase family M41 SIRE_RS01200 PF00117 Glutamine amidotransferase class-I SIRE_RS01200 PF00958 GMP synthase C terminal domain SIRE_RS01200 PF02540 NAD synthase SIRE_RS01205 PF06745 KaiC SIRE_RS01215 PF04493 Endonuclease V SIRE_RS01220 PF00857 Isochorismatase family SIRE_RS01225 PF02272 DHHA1 domain SIRE_RS01225 PF01368 DHH family SIRE_RS01255 PF00270 DEAD/DEAH box helicase SIRE_RS01255 PF00271 Helicase conserved C-terminal domain SIRE_RS01255 PF08148 DSHCT (NUC185) domain SIRE_RS01265 PF01039 Carboxyl transferase domain SIRE_RS01275 PF02785 Biotin carboxylase C-terminal domain SIRE_RS01275 PF00289 Biotin carboxylase, N-terminal domain SIRE_RS01275 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SIRE_RS01295 PF00005 ABC transporter SIRE_RS01305 PF00694 Aconitase C-terminal domain SIRE_RS01310 PF00330 Aconitase family (aconitate hydratase) SIRE_RS01315 PF00875 DNA photolyase SIRE_RS01315 PF03441 FAD binding domain of DNA photolyase SIRE_RS01345 PF00474 Sodium:solute symporter family SIRE_RS01350 PF02146 Sir2 family SIRE_RS01360 PF00483 Nucleotidyl transferase SIRE_RS01390 PF00549 CoA-ligase SIRE_RS01390 PF02629 CoA binding domain SIRE_RS01395 PF00549 CoA-ligase SIRE_RS01395 PF08442 ATP-grasp domain SIRE_RS01410 PF03129 Anticodon binding domain SIRE_RS01410 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SIRE_RS01410 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SIRE_RS01410 PF02824 TGS domain SIRE_RS01415 PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain SIRE_RS01415 PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain SIRE_RS01465 PF07859 alpha/beta hydrolase fold SIRE_RS01470 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS01470 PF00107 Zinc-binding dehydrogenase SIRE_RS01475 PF02803 Thiolase, C-terminal domain SIRE_RS01475 PF00108 Thiolase, N-terminal domain SIRE_RS01480 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SIRE_RS01480 PF02770 Acyl-CoA dehydrogenase, middle domain SIRE_RS01480 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SIRE_RS01485 PF00268 Ribonucleotide reductase, small chain SIRE_RS01495 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS01495 PF00107 Zinc-binding dehydrogenase SIRE_RS01505 PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal SIRE_RS01505 PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal SIRE_RS01510 PF07690 Major Facilitator Superfamily SIRE_RS01515 PF16925 Tetracyclin repressor-like, C-terminal domain SIRE_RS01515 PF00440 Bacterial regulatory proteins, tetR family SIRE_RS01535 PF00501 AMP-binding enzyme SIRE_RS01535 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS01540 PF02770 Acyl-CoA dehydrogenase, middle domain SIRE_RS01540 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SIRE_RS01540 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SIRE_RS01545 PF00378 Enoyl-CoA hydratase/isomerase SIRE_RS01550 PF00753 Metallo-beta-lactamase superfamily SIRE_RS01555 PF00083 Sugar (and other) transporter SIRE_RS01580 PF07859 alpha/beta hydrolase fold SIRE_RS01585 PF02126 Phosphotriesterase family SIRE_RS01590 PF00501 AMP-binding enzyme SIRE_RS01590 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS01600 PF04324 BFD-like [2Fe-2S] binding domain SIRE_RS01600 PF01266 FAD dependent oxidoreductase SIRE_RS01605 PF00370 FGGY family of carbohydrate kinases, N-terminal domain SIRE_RS01605 PF02782 FGGY family of carbohydrate kinases, C-terminal domain SIRE_RS01625 PF00005 ABC transporter SIRE_RS01675 PF14759 Reductase C-terminal SIRE_RS01675 PF07992 Pyridine nucleotide-disulphide oxidoreductase SIRE_RS01690 PF01894 Uncharacterised protein family UPF0047 SIRE_RS01695 PF01841 Transglutaminase-like superfamily SIRE_RS01695 PF08379 Bacterial transglutaminase-like N-terminal region SIRE_RS01710 PF01037 Lrp/AsnC ligand binding domain SIRE_RS01715 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SIRE_RS01720 PF17147 Pyruvate:ferredoxin oxidoreductase core domain II SIRE_RS01720 PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg SIRE_RS01725 PF00037 4Fe-4S binding domain SIRE_RS01730 PF07690 Major Facilitator Superfamily SIRE_RS01735 PF02652 L-lactate permease SIRE_RS01750 PF01425 Amidase SIRE_RS01755 PF00578 AhpC/TSA family SIRE_RS01755 PF10417 C-terminal domain of 1-Cys peroxiredoxin SIRE_RS01775 PF00474 Sodium:solute symporter family SIRE_RS01800 PF00890 FAD binding domain SIRE_RS01820 PF02223 Thymidylate kinase SIRE_RS01825 PF02223 Thymidylate kinase SIRE_RS01835 PF00300 Histidine phosphatase superfamily (branch 1) SIRE_RS01840 PF12837 4Fe-4S binding domain SIRE_RS01840 PF13247 4Fe-4S dicluster domain SIRE_RS01840 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SIRE_RS01845 PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg SIRE_RS01845 PF17147 Pyruvate:ferredoxin oxidoreductase core domain II SIRE_RS01855 PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase SIRE_RS01890 PF02913 FAD linked oxidases, C-terminal domain SIRE_RS01890 PF01565 FAD binding domain SIRE_RS01905 PF00171 Aldehyde dehydrogenase family SIRE_RS01915 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS01915 PF00107 Zinc-binding dehydrogenase SIRE_RS01930 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SIRE_RS01935 PF03928 Haem-degrading SIRE_RS01940 PF14759 Reductase C-terminal SIRE_RS01940 PF07992 Pyridine nucleotide-disulphide oxidoreductase SIRE_RS01950 PF02332 Methane/Phenol/Toluene Hydroxylase SIRE_RS01955 PF02332 Methane/Phenol/Toluene Hydroxylase SIRE_RS01955 PF04945 YHS domain SIRE_RS01980 PF01883 Iron-sulfur cluster assembly protein SIRE_RS01985 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SIRE_RS01985 PF00205 Thiamine pyrophosphate enzyme, central domain SIRE_RS01985 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SIRE_RS02000 PF02678 Pirin SIRE_RS02000 PF05726 Pirin C-terminal cupin domain SIRE_RS02010 PF07690 Major Facilitator Superfamily SIRE_RS02015 PF00378 Enoyl-CoA hydratase/isomerase SIRE_RS02020 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS02020 PF00107 Zinc-binding dehydrogenase SIRE_RS02025 PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain SIRE_RS02025 PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain SIRE_RS02040 PF00171 Aldehyde dehydrogenase family SIRE_RS02075 PF02585 GlcNAc-PI de-N-acetylase SIRE_RS02085 PF12002 MgsA AAA+ ATPase C terminal SIRE_RS02085 PF01661 Macro domain SIRE_RS02085 PF16193 AAA C-terminal domain SIRE_RS02085 PF05496 Holliday junction DNA helicase RuvB P-loop domain SIRE_RS02090 PF01385 Probable transposase SIRE_RS02090 PF12323 Helix-turn-helix domain SIRE_RS02090 PF07282 Putative transposase DNA-binding domain SIRE_RS02100 PF00042 Globin SIRE_RS02135 PF00005 ABC transporter SIRE_RS02135 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SIRE_RS02140 PF00005 ABC transporter SIRE_RS02140 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SIRE_RS02150 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS02165 PF02272 DHHA1 domain SIRE_RS02165 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SIRE_RS02165 PF01411 tRNA synthetases class II (A) SIRE_RS02180 PF01380 SIS domain SIRE_RS02185 PF13732 Domain of unknown function (DUF4162) SIRE_RS02185 PF00005 ABC transporter SIRE_RS02210 PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus SIRE_RS02210 PF08666 SAF domain SIRE_RS02215 PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus SIRE_RS02220 PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SIRE_RS02220 PF13378 Enolase C-terminal domain-like SIRE_RS02230 PF03824 High-affinity nickel-transport protein SIRE_RS02235 PF00392 Bacterial regulatory proteins, gntR family SIRE_RS02235 PF07729 FCD domain SIRE_RS02240 PF03328 HpcH/HpaI aldolase/citrate lyase family SIRE_RS02245 PF03061 Thioesterase superfamily SIRE_RS02245 PF01008 Initiation factor 2 subunit family SIRE_RS02275 PF02665 Nitrate reductase gamma subunit SIRE_RS02280 PF02613 Nitrate reductase delta subunit SIRE_RS02285 PF14711 Respiratory nitrate reductase beta C-terminal SIRE_RS02285 PF13247 4Fe-4S dicluster domain SIRE_RS02305 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS02305 PF00501 AMP-binding enzyme SIRE_RS02335 PF01566 Natural resistance-associated macrophage protein SIRE_RS02415 PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase SIRE_RS02415 PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SIRE_RS02470 PF01738 Dienelactone hydrolase family SIRE_RS02485 PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase SIRE_RS02485 PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain SIRE_RS02495 PF00128 Alpha amylase, catalytic domain SIRE_RS02495 PF11941 Domain of unknown function (DUF3459) SIRE_RS02500 PF18390 Glycogen debranching enzyme C-terminal domain SIRE_RS02500 PF00128 Alpha amylase, catalytic domain SIRE_RS02500 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SIRE_RS02510 PF00128 Alpha amylase, catalytic domain SIRE_RS02510 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SIRE_RS02515 PF00128 Alpha amylase, catalytic domain SIRE_RS02520 PF03572 Peptidase family S41 SIRE_RS02520 PF14685 Tricorn protease PDZ domain SIRE_RS02520 PF07676 WD40-like Beta Propeller Repeat SIRE_RS02520 PF14684 Tricorn protease C1 domain SIRE_RS02525 PF01872 RibD C-terminal domain SIRE_RS02590 PF01470 Pyroglutamyl peptidase SIRE_RS02605 PF00230 Major intrinsic protein SIRE_RS02610 PF00370 FGGY family of carbohydrate kinases, N-terminal domain SIRE_RS02610 PF02782 FGGY family of carbohydrate kinases, C-terminal domain SIRE_RS02625 PF03176 MMPL family SIRE_RS02630 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SIRE_RS02630 PF12806 Acetyl-CoA dehydrogenase C-terminal like SIRE_RS02630 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SIRE_RS02630 PF02770 Acyl-CoA dehydrogenase, middle domain SIRE_RS02635 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS02635 PF00501 AMP-binding enzyme SIRE_RS02650 PF07690 Major Facilitator Superfamily SIRE_RS02720 PF00384 Molybdopterin oxidoreductase SIRE_RS02720 PF01568 Molydopterin dinucleotide binding domain SIRE_RS02725 PF13247 4Fe-4S dicluster domain SIRE_RS02745 PF00115 Cytochrome C and Quinol oxidase polypeptide I SIRE_RS02765 PF16123 Hydroxyacylglutathione hydrolase C-terminus SIRE_RS02765 PF00753 Metallo-beta-lactamase superfamily SIRE_RS02825 PF02538 Hydantoinase B/oxoprolinase SIRE_RS02830 PF05378 Hydantoinase/oxoprolinase N-terminal region SIRE_RS02830 PF01968 Hydantoinase/oxoprolinase SIRE_RS02840 PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin SIRE_RS02870 PF07690 Major Facilitator Superfamily SIRE_RS02875 PF13378 Enolase C-terminal domain-like SIRE_RS02875 PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SIRE_RS02880 PF00107 Zinc-binding dehydrogenase SIRE_RS02880 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS02900 PF00005 ABC transporter SIRE_RS02910 PF01546 Peptidase family M20/M25/M40 SIRE_RS02910 PF07687 Peptidase dimerisation domain SIRE_RS02915 PF00083 Sugar (and other) transporter SIRE_RS02915 PF08946 Osmosensory transporter coiled coil SIRE_RS02940 PF00753 Metallo-beta-lactamase superfamily SIRE_RS02955 PF00296 Luciferase-like monooxygenase SIRE_RS03005 PF00005 ABC transporter SIRE_RS03020 PF00271 Helicase conserved C-terminal domain SIRE_RS03020 PF00176 SNF2 family N-terminal domain SIRE_RS03155 PF04851 Type III restriction enzyme, res subunit SIRE_RS03155 PF02151 UvrB/uvrC motif SIRE_RS03155 PF00271 Helicase conserved C-terminal domain SIRE_RS03155 PF12344 Ultra-violet resistance protein B SIRE_RS03155 PF17757 UvrB interaction domain SIRE_RS03210 PF04343 Protein of unknown function, DUF488 SIRE_RS03225 PF12323 Helix-turn-helix domain SIRE_RS03225 PF07282 Putative transposase DNA-binding domain SIRE_RS03225 PF01385 Probable transposase SIRE_RS03235 PF00582 Universal stress protein family SIRE_RS03250 PF06745 KaiC SIRE_RS03255 PF02673 Bacitracin resistance protein BacA SIRE_RS03260 PF01435 Peptidase family M48 SIRE_RS03265 PF00117 Glutamine amidotransferase class-I SIRE_RS03280 PF01979 Amidohydrolase family SIRE_RS03305 PF01209 ubiE/COQ5 methyltransferase family SIRE_RS03325 PF13380 CoA binding domain SIRE_RS03325 PF00583 Acetyltransferase (GNAT) family SIRE_RS03325 PF13607 Succinyl-CoA ligase like flavodoxin domain SIRE_RS03360 PF01206 Sulfurtransferase TusA SIRE_RS03370 PF00378 Enoyl-CoA hydratase/isomerase SIRE_RS03400 PF07992 Pyridine nucleotide-disulphide oxidoreductase SIRE_RS03400 PF00724 NADH:flavin oxidoreductase / NADH oxidase family SIRE_RS03430 PF13419 Haloacid dehalogenase-like hydrolase SIRE_RS03440 PF12558 ATP-binding cassette cobalt transporter SIRE_RS03440 PF00005 ABC transporter SIRE_RS03465 PF03880 DbpA RNA binding domain SIRE_RS03465 PF00270 DEAD/DEAH box helicase SIRE_RS03465 PF00271 Helicase conserved C-terminal domain SIRE_RS03480 PF07690 Major Facilitator Superfamily SIRE_RS03480 PF00083 Sugar (and other) transporter SIRE_RS03485 PF01979 Amidohydrolase family SIRE_RS03490 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS03490 PF00501 AMP-binding enzyme SIRE_RS03495 PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin SIRE_RS03500 PF13520 Amino acid permease SIRE_RS03505 PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SIRE_RS03505 PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SIRE_RS03520 PF07282 Putative transposase DNA-binding domain SIRE_RS03520 PF01385 Probable transposase SIRE_RS03520 PF12323 Helix-turn-helix domain SIRE_RS03545 PF07690 Major Facilitator Superfamily SIRE_RS03590 PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal SIRE_RS03590 PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal SIRE_RS03595 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SIRE_RS03600 PF01613 Flavin reductase like domain SIRE_RS03605 PF00083 Sugar (and other) transporter SIRE_RS03615 PF16177 Acetyl-coenzyme A synthetase N-terminus SIRE_RS03615 PF00501 AMP-binding enzyme SIRE_RS03615 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS03620 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SIRE_RS03620 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SIRE_RS03620 PF02770 Acyl-CoA dehydrogenase, middle domain SIRE_RS03665 PF00501 AMP-binding enzyme SIRE_RS03665 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS03665 PF16177 Acetyl-coenzyme A synthetase N-terminus SIRE_RS03670 PF00578 AhpC/TSA family SIRE_RS03705 PF00005 ABC transporter SIRE_RS03715 PF12323 Helix-turn-helix domain SIRE_RS03715 PF01385 Probable transposase SIRE_RS03715 PF07282 Putative transposase DNA-binding domain SIRE_RS03730 PF02515 CoA-transferase family III SIRE_RS03735 PF00501 AMP-binding enzyme SIRE_RS03735 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS03740 PF00083 Sugar (and other) transporter SIRE_RS03745 PF01274 Malate synthase SIRE_RS03750 PF00463 Isocitrate lyase family SIRE_RS03765 PF01544 CorA-like Mg2+ transporter protein SIRE_RS03770 PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase SIRE_RS03795 PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SIRE_RS03795 PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SIRE_RS03815 PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain SIRE_RS03815 PF01450 Acetohydroxy acid isomeroreductase, catalytic domain SIRE_RS03850 PF01867 CRISPR associated protein Cas1 SIRE_RS03890 PF17191 RecG wedge domain SIRE_RS03890 PF00271 Helicase conserved C-terminal domain SIRE_RS03890 PF00270 DEAD/DEAH box helicase SIRE_RS03915 PF07282 Putative transposase DNA-binding domain SIRE_RS03915 PF01385 Probable transposase SIRE_RS03915 PF12323 Helix-turn-helix domain SIRE_RS03935 PF13173 AAA domain SIRE_RS03935 PF13635 Domain of unknown function (DUF4143) SIRE_RS03975 PF00535 Glycosyl transferase family 2 SIRE_RS03985 PF07687 Peptidase dimerisation domain SIRE_RS03985 PF01546 Peptidase family M20/M25/M40 SIRE_RS04040 PF00005 ABC transporter SIRE_RS04110 PF02463 RecF/RecN/SMC N terminal domain SIRE_RS04190 PF08402 TOBE domain SIRE_RS04190 PF00005 ABC transporter SIRE_RS04250 PF16363 GDP-mannose 4,6 dehydratase SIRE_RS04255 PF00483 Nucleotidyl transferase SIRE_RS04260 PF04321 RmlD substrate binding domain SIRE_RS04265 PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase SIRE_RS04270 PF08241 Methyltransferase domain SIRE_RS04300 PF00535 Glycosyl transferase family 2 SIRE_RS04310 PF05958 tRNA (Uracil-5-)-methyltransferase SIRE_RS04310 PF01938 TRAM domain SIRE_RS04320 PF13439 Glycosyltransferase Family 4 SIRE_RS04320 PF00534 Glycosyl transferases group 1 SIRE_RS04355 PF01501 Glycosyl transferase family 8 SIRE_RS04355 PF00535 Glycosyl transferase family 2 SIRE_RS04380 PF00534 Glycosyl transferases group 1 SIRE_RS04380 PF13439 Glycosyltransferase Family 4 SIRE_RS04415 PF00884 Sulfatase SIRE_RS04415 PF16347 Domain of unknown function (DUF4976) SIRE_RS04420 PF00535 Glycosyl transferase family 2 SIRE_RS04435 PF01507 Phosphoadenosine phosphosulfate reductase family SIRE_RS04445 PF05958 tRNA (Uracil-5-)-methyltransferase SIRE_RS04460 PF01385 Probable transposase SIRE_RS04460 PF07282 Putative transposase DNA-binding domain SIRE_RS04460 PF12323 Helix-turn-helix domain SIRE_RS04590 PF04055 Radical SAM superfamily SIRE_RS04590 PF13186 Iron-sulfur cluster-binding domain SIRE_RS04595 PF13186 Iron-sulfur cluster-binding domain SIRE_RS04595 PF04055 Radical SAM superfamily SIRE_RS04600 PF00171 Aldehyde dehydrogenase family SIRE_RS04715 PF00083 Sugar (and other) transporter SIRE_RS04720 PF08241 Methyltransferase domain SIRE_RS04725 PF00155 Aminotransferase class I and II SIRE_RS04765 PF07690 Major Facilitator Superfamily SIRE_RS04780 PF13419 Haloacid dehalogenase-like hydrolase SIRE_RS04800 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SIRE_RS04800 PF02770 Acyl-CoA dehydrogenase, middle domain SIRE_RS04800 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SIRE_RS04805 PF07521 Zn-dependent metallo-hydrolase RNA specificity domain SIRE_RS04805 PF17770 Ribonuclease J C-terminal domain SIRE_RS04805 PF00753 Metallo-beta-lactamase superfamily SIRE_RS04830 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SIRE_RS04830 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SIRE_RS04830 PF02770 Acyl-CoA dehydrogenase, middle domain SIRE_RS04870 PF00083 Sugar (and other) transporter SIRE_RS04870 PF07690 Major Facilitator Superfamily SIRE_RS04875 PF00291 Pyridoxal-phosphate dependent enzyme SIRE_RS04880 PF00005 ABC transporter SIRE_RS04905 PF00999 Sodium/hydrogen exchanger family SIRE_RS04920 PF02754 Cysteine-rich domain SIRE_RS04935 PF01593 Flavin containing amine oxidoreductase SIRE_RS04950 PF01206 Sulfurtransferase TusA SIRE_RS04955 PF13686 DsrE/DsrF/DrsH-like family SIRE_RS04965 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SIRE_RS04965 PF07992 Pyridine nucleotide-disulphide oxidoreductase SIRE_RS04990 PF00850 Histone deacetylase domain SIRE_RS05000 PF04055 Radical SAM superfamily SIRE_RS05000 PF06968 Biotin and Thiamin Synthesis associated domain SIRE_RS05010 PF03099 Biotin/lipoate A/B protein ligase family SIRE_RS05015 PF13380 CoA binding domain SIRE_RS05045 PF01597 Glycine cleavage H-protein SIRE_RS05095 PF00694 Aconitase C-terminal domain SIRE_RS05095 PF00330 Aconitase family (aconitate hydratase) SIRE_RS05115 PF00149 Calcineurin-like phosphoesterase SIRE_RS05120 PF16697 Inner membrane component of T3SS, cytoplasmic domain SIRE_RS05140 PF01144 Coenzyme A transferase SIRE_RS05150 PF01047 MarR family SIRE_RS05155 PF12704 MacB-like periplasmic core domain SIRE_RS05155 PF02687 FtsX-like permease family SIRE_RS05155 PF00005 ABC transporter SIRE_RS05165 PF00005 ABC transporter SIRE_RS05170 PF10415 Fumarase C C-terminus SIRE_RS05170 PF00206 Lyase SIRE_RS05180 PF00571 CBS domain SIRE_RS05185 PF13462 Thioredoxin SIRE_RS05185 PF06965 Na+/H+ antiporter 1 SIRE_RS05190 PF13520 Amino acid permease SIRE_RS05195 PF01965 DJ-1/PfpI family SIRE_RS05205 PF17769 Phosphoribosylaminoimidazole carboxylase C-terminal domain SIRE_RS05205 PF02222 ATP-grasp domain SIRE_RS05210 PF00731 AIR carboxylase SIRE_RS05230 PF01597 Glycine cleavage H-protein SIRE_RS05270 PF00909 Ammonium Transporter Family SIRE_RS05290 PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain SIRE_RS05290 PF01138 3' exoribonuclease family, domain 1 SIRE_RS05290 PF03725 3' exoribonuclease family, domain 2 SIRE_RS05290 PF00575 S1 RNA binding domain SIRE_RS05290 PF00013 KH domain SIRE_RS05325 PF13793 N-terminal domain of ribose phosphate pyrophosphokinase SIRE_RS05325 PF14572 Phosphoribosyl synthetase-associated domain SIRE_RS05335 PF12706 Beta-lactamase superfamily domain SIRE_RS05350 PF02834 LigT like Phosphoesterase SIRE_RS05385 PF16326 ABC transporter C-terminal domain SIRE_RS05385 PF00005 ABC transporter SIRE_RS05385 PF12848 ABC transporter SIRE_RS05400 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS05410 PF00106 short chain dehydrogenase SIRE_RS05415 PF00384 Molybdopterin oxidoreductase SIRE_RS05415 PF01568 Molydopterin dinucleotide binding domain SIRE_RS05415 PF04879 Molybdopterin oxidoreductase Fe4S4 domain SIRE_RS05440 PF00361 Proton-conducting membrane transporter SIRE_RS05440 PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus SIRE_RS05445 PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit SIRE_RS05450 PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit SIRE_RS05455 PF00361 Proton-conducting membrane transporter SIRE_RS05465 PF00581 Rhodanese-like domain SIRE_RS05470 PF03824 High-affinity nickel-transport protein SIRE_RS05490 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SIRE_RS05490 PF00205 Thiamine pyrophosphate enzyme, central domain SIRE_RS05490 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SIRE_RS05495 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SIRE_RS05495 PF07992 Pyridine nucleotide-disulphide oxidoreductase SIRE_RS05500 PF08402 TOBE domain SIRE_RS05500 PF00005 ABC transporter SIRE_RS05505 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS05510 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS05520 PF02445 Quinolinate synthetase A protein SIRE_RS05525 PF02910 Fumarate reductase flavoprotein C-term SIRE_RS05525 PF00890 FAD binding domain SIRE_RS05530 PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain SIRE_RS05530 PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain SIRE_RS05560 PF00483 Nucleotidyl transferase SIRE_RS05560 PF00132 Bacterial transferase hexapeptide (six repeats) SIRE_RS05570 PF08323 Starch synthase catalytic domain SIRE_RS05570 PF00534 Glycosyl transferases group 1 SIRE_RS05580 PF01266 FAD dependent oxidoreductase SIRE_RS05595 PF02887 Pyruvate kinase, alpha/beta domain SIRE_RS05595 PF00224 Pyruvate kinase, barrel domain SIRE_RS05610 PF08502 LeuA allosteric (dimerisation) domain SIRE_RS05610 PF00682 HMGL-like SIRE_RS05620 PF00696 Amino acid kinase family SIRE_RS05635 PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase SIRE_RS05635 PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SIRE_RS05645 PF02881 SRP54-type protein, helical bundle domain SIRE_RS05645 PF00448 SRP54-type protein, GTPase domain SIRE_RS05645 PF02978 Signal peptide binding domain SIRE_RS05650 PF09285 Elongation factor P, C-terminal SIRE_RS05650 PF08207 Elongation factor P (EF-P) KOW-like domain SIRE_RS05650 PF01132 Elongation factor P (EF-P) OB domain SIRE_RS05660 PF00416 Ribosomal protein S13/S18 SIRE_RS05670 PF01139 tRNA-splicing ligase RtcB SIRE_RS05690 PF00270 DEAD/DEAH box helicase SIRE_RS05690 PF17915 Reverse gyrase zinc finger SIRE_RS05690 PF01131 DNA topoisomerase SIRE_RS05690 PF01751 Toprim domain SIRE_RS05725 PF02686 Glu-tRNAGln amidotransferase C subunit SIRE_RS05730 PF01425 Amidase SIRE_RS05745 PF00294 pfkB family carbohydrate kinase SIRE_RS05745 PF01467 Cytidylyltransferase-like SIRE_RS05800 PF02005 N2,N2-dimethylguanosine tRNA methyltransferase SIRE_RS05830 PF17763 Glutaminase/Asparaginase C-terminal domain SIRE_RS05830 PF00710 Asparaginase, N-terminal SIRE_RS05835 PF02637 GatB domain SIRE_RS05835 PF02934 GatB/GatE catalytic domain SIRE_RS05850 PF00317 Ribonucleotide reductase, all-alpha domain SIRE_RS05850 PF02867 Ribonucleotide reductase, barrel domain SIRE_RS05850 PF03477 ATP cone domain SIRE_RS05865 PF01458 Uncharacterized protein family (UPF0051) SIRE_RS05865 PF14528 LAGLIDADG-like domain SIRE_RS05870 PF01458 Uncharacterized protein family (UPF0051) SIRE_RS05875 PF00005 ABC transporter SIRE_RS05895 PF01597 Glycine cleavage H-protein SIRE_RS05900 PF08669 Glycine cleavage T-protein C-terminal barrel domain SIRE_RS05900 PF01571 Aminomethyltransferase folate-binding domain SIRE_RS05905 PF02347 Glycine cleavage system P-protein SIRE_RS05910 PF02347 Glycine cleavage system P-protein SIRE_RS05930 PF03952 Enolase, N-terminal domain SIRE_RS05930 PF00113 Enolase, C-terminal TIM barrel domain SIRE_RS05950 PF00004 ATPase family associated with various cellular activities (AAA) SIRE_RS05950 PF01434 Peptidase family M41 SIRE_RS05950 PF06480 FtsH Extracellular SIRE_RS05950 PF17862 AAA+ lid domain SIRE_RS05955 PF01751 Toprim domain SIRE_RS05955 PF01131 DNA topoisomerase SIRE_RS05965 PF00266 Aminotransferase class-V SIRE_RS05970 PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain SIRE_RS05970 PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SIRE_RS06000 PF01494 FAD binding domain SIRE_RS06005 PF00133 tRNA synthetases class I (I, L, M and V) SIRE_RS06005 PF08264 Anticodon-binding domain of tRNA SIRE_RS06010 PF00155 Aminotransferase class I and II SIRE_RS06015 PF00218 Indole-3-glycerol phosphate synthase SIRE_RS06020 PF00117 Glutamine amidotransferase class-I SIRE_RS06020 PF00591 Glycosyl transferase family, a/b domain SIRE_RS06020 PF02885 Glycosyl transferase family, helical bundle domain SIRE_RS06025 PF00425 chorismate binding enzyme SIRE_RS06025 PF04715 Anthranilate synthase component I, N terminal region SIRE_RS06030 PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase SIRE_RS06035 PF00591 Glycosyl transferase family, a/b domain SIRE_RS06035 PF02885 Glycosyl transferase family, helical bundle domain SIRE_RS06040 PF00290 Tryptophan synthase alpha chain SIRE_RS06045 PF00291 Pyridoxal-phosphate dependent enzyme SIRE_RS06050 PF00708 Acylphosphatase SIRE_RS06055 PF01658 Myo-inositol-1-phosphate synthase SIRE_RS06060 PF00391 PEP-utilising enzyme, mobile domain SIRE_RS06060 PF02896 PEP-utilising enzyme, TIM barrel domain SIRE_RS06060 PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain SIRE_RS06075 PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase SIRE_RS06080 PF00291 Pyridoxal-phosphate dependent enzyme SIRE_RS06085 PF00696 Amino acid kinase family SIRE_RS06085 PF03447 Homoserine dehydrogenase, NAD binding domain SIRE_RS06085 PF00742 Homoserine dehydrogenase SIRE_RS06090 PF01118 Semialdehyde dehydrogenase, NAD binding domain SIRE_RS06090 PF02774 Semialdehyde dehydrogenase, dimerisation domain SIRE_RS06105 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SIRE_RS06105 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SIRE_RS06140 PF00118 TCP-1/cpn60 chaperonin family SIRE_RS06160 PF05746 DALR anticodon binding domain SIRE_RS06160 PF00750 tRNA synthetases class I (R) SIRE_RS06160 PF03485 Arginyl tRNA synthetase N terminal domain SIRE_RS06185 PF02223 Thymidylate kinase SIRE_RS06245 PF01967 MoaC family SIRE_RS06250 PF16193 AAA C-terminal domain SIRE_RS06250 PF12002 MgsA AAA+ ATPase C terminal SIRE_RS06250 PF05496 Holliday junction DNA helicase RuvB P-loop domain SIRE_RS06255 PF17864 RuvB AAA lid domain SIRE_RS06255 PF05496 Holliday junction DNA helicase RuvB P-loop domain SIRE_RS06255 PF05491 RuvB C-terminal winged helix domain SIRE_RS06260 PF01161 Phosphatidylethanolamine-binding protein SIRE_RS06265 PF00227 Proteasome subunit SIRE_RS06270 PF01425 Amidase SIRE_RS06275 PF00107 Zinc-binding dehydrogenase SIRE_RS06275 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS06320 PF02899 Phage integrase, N-terminal SAM-like domain SIRE_RS06320 PF00589 Phage integrase family SIRE_RS06330 PF00753 Metallo-beta-lactamase superfamily SIRE_RS06330 PF07521 Zn-dependent metallo-hydrolase RNA specificity domain SIRE_RS06330 PF10996 Beta-Casp domain SIRE_RS06335 PF13685 Iron-containing alcohol dehydrogenase SIRE_RS06340 PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase SIRE_RS06355 PF17284 Spermidine synthase tetramerisation domain SIRE_RS06370 PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain SIRE_RS06370 PF05221 S-adenosyl-L-homocysteine hydrolase SIRE_RS06410 PF00398 Ribosomal RNA adenine dimethylase SIRE_RS06420 PF00588 SpoU rRNA Methylase family SIRE_RS06430 PF00483 Nucleotidyl transferase SIRE_RS06435 PF06071 Protein of unknown function (DUF933) SIRE_RS06435 PF01926 50S ribosome-binding GTPase SIRE_RS06475 PF00013 KH domain SIRE_RS06475 PF03725 3' exoribonuclease family, domain 2 SIRE_RS06475 PF01138 3' exoribonuclease family, domain 1 SIRE_RS06475 PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain SIRE_RS06475 PF00575 S1 RNA binding domain SIRE_RS06480 PF03725 3' exoribonuclease family, domain 2 SIRE_RS06480 PF01138 3' exoribonuclease family, domain 1 SIRE_RS06500 PF12826 Helix-hairpin-helix motif SIRE_RS06500 PF02151 UvrB/uvrC motif SIRE_RS06500 PF08459 UvrC Helix-hairpin-helix N-terminal SIRE_RS06500 PF01541 GIY-YIG catalytic domain SIRE_RS06505 PF03144 Elongation factor Tu domain 2 SIRE_RS06505 PF00009 Elongation factor Tu GTP binding domain SIRE_RS06505 PF03764 Elongation factor G, domain IV SIRE_RS06505 PF14492 Elongation Factor G, domain II SIRE_RS06505 PF00679 Elongation factor G C-terminus SIRE_RS06525 PF00180 Isocitrate/isopropylmalate dehydrogenase SIRE_RS06530 PF08264 Anticodon-binding domain of tRNA SIRE_RS06530 PF00133 tRNA synthetases class I (I, L, M and V) SIRE_RS06540 PF00297 Ribosomal protein L3 SIRE_RS06550 PF00276 Ribosomal protein L23 SIRE_RS06555 PF00181 Ribosomal Proteins L2, RNA binding domain SIRE_RS06555 PF03947 Ribosomal Proteins L2, C-terminal domain SIRE_RS06560 PF00203 Ribosomal protein S19 SIRE_RS06565 PF00237 Ribosomal protein L22p/L17e SIRE_RS06570 PF07650 KH domain SIRE_RS06570 PF00189 Ribosomal protein S3, C-terminal domain SIRE_RS06575 PF00831 Ribosomal L29 protein SIRE_RS06585 PF00366 Ribosomal protein S17 SIRE_RS06590 PF00238 Ribosomal protein L14p/L23e SIRE_RS06595 PF00467 KOW motif SIRE_RS06595 PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 SIRE_RS06605 PF00673 ribosomal L5P family C-terminus SIRE_RS06605 PF00281 Ribosomal protein L5 SIRE_RS06615 PF00410 Ribosomal protein S8 SIRE_RS06620 PF00347 Ribosomal protein L6 SIRE_RS06640 PF00333 Ribosomal protein S5, N-terminal domain SIRE_RS06640 PF03719 Ribosomal protein S5, C-terminal domain SIRE_RS06655 PF00344 SecY translocase SIRE_RS06675 PF05191 Adenylate kinase, active site lid SIRE_RS06750 PF12704 MacB-like periplasmic core domain SIRE_RS06750 PF00005 ABC transporter SIRE_RS06750 PF02687 FtsX-like permease family SIRE_RS06760 PF01645 Conserved region in glutamate synthase SIRE_RS06760 PF13187 4Fe-4S dicluster domain SIRE_RS06765 PF00310 Glutamine amidotransferases class-II SIRE_RS06780 PF01979 Amidohydrolase family SIRE_RS06785 PF00764 Arginosuccinate synthase SIRE_RS06795 PF00994 Probable molybdopterin binding domain SIRE_RS06795 PF03453 MoeA N-terminal region (domain I and II) SIRE_RS06795 PF03454 MoeA C-terminal region (domain IV) SIRE_RS06810 PF01209 ubiE/COQ5 methyltransferase family SIRE_RS06830 PF02742 Iron dependent repressor, metal binding and dimerisation domain SIRE_RS06830 PF01325 Iron dependent repressor, N-terminal DNA binding domain SIRE_RS06830 PF18357 Diphteria toxin repressor SH3 domain SIRE_RS06840 PF05161 MOFRL family SIRE_RS06840 PF13660 Domain of unknown function (DUF4147) SIRE_RS06845 PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit SIRE_RS06850 PF03481 Putative GTP-binding controlling metal-binding SIRE_RS06850 PF01300 Telomere recombination SIRE_RS06855 PF02237 Biotin protein ligase C terminal domain SIRE_RS06855 PF08279 HTH domain SIRE_RS06855 PF03099 Biotin/lipoate A/B protein ligase family SIRE_RS06865 PF01523 Putative modulator of DNA gyrase SIRE_RS06870 PF01523 Putative modulator of DNA gyrase SIRE_RS06875 PF01402 Ribbon-helix-helix protein, copG family SIRE_RS06875 PF08753 NikR C terminal nickel binding domain SIRE_RS06885 PF01842 ACT domain SIRE_RS06885 PF03447 Homoserine dehydrogenase, NAD binding domain SIRE_RS06885 PF00742 Homoserine dehydrogenase SIRE_RS06890 PF01040 UbiA prenyltransferase family SIRE_RS06900 PF00378 Enoyl-CoA hydratase/isomerase SIRE_RS06940 PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SIRE_RS06940 PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SIRE_RS06950 PF08443 RimK-like ATP-grasp domain SIRE_RS06955 PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain SIRE_RS06955 PF02142 MGS-like domain SIRE_RS06955 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SIRE_RS06960 PF00117 Glutamine amidotransferase class-I SIRE_RS06960 PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain SIRE_RS06965 PF14698 Argininosuccinate lyase C-terminal SIRE_RS06965 PF00206 Lyase SIRE_RS06970 PF00764 Arginosuccinate synthase SIRE_RS06985 PF02769 AIR synthase related protein, C-terminal domain SIRE_RS06985 PF00586 AIR synthase related protein, N-terminal domain SIRE_RS06990 PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SIRE_RS06990 PF02843 Phosphoribosylglycinamide synthetase, C domain SIRE_RS06990 PF02844 Phosphoribosylglycinamide synthetase, N domain SIRE_RS06995 PF00156 Phosphoribosyl transferase domain SIRE_RS07000 PF00156 Phosphoribosyl transferase domain SIRE_RS07005 PF00586 AIR synthase related protein, N-terminal domain SIRE_RS07005 PF02769 AIR synthase related protein, C-terminal domain SIRE_RS07005 PF18072 Formylglycinamide ribonucleotide amidotransferase linker domain SIRE_RS07020 PF01259 SAICAR synthetase SIRE_RS07025 PF01588 Putative tRNA binding domain SIRE_RS07025 PF09334 tRNA synthetases class I (M) SIRE_RS07025 PF08264 Anticodon-binding domain of tRNA SIRE_RS07030 PF01926 50S ribosome-binding GTPase SIRE_RS07030 PF09269 Domain of unknown function (DUF1967) SIRE_RS07030 PF01018 GTP1/OBG SIRE_RS07035 PF04055 Radical SAM superfamily SIRE_RS07070 PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family SIRE_RS07075 PF00156 Phosphoribosyl transferase domain SIRE_RS07080 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SIRE_RS07080 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SIRE_RS07085 PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain SIRE_RS07085 PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain SIRE_RS07095 PF01979 Amidohydrolase family SIRE_RS07100 PF01180 Dihydroorotate dehydrogenase SIRE_RS07115 PF01914 MarC family integral membrane protein SIRE_RS07120 PF01037 Lrp/AsnC ligand binding domain SIRE_RS07120 PF13404 AsnC-type helix-turn-helix domain SIRE_RS07135 PF00919 Uncharacterized protein family UPF0004 SIRE_RS07135 PF04055 Radical SAM superfamily SIRE_RS07135 PF01938 TRAM domain SIRE_RS07140 PF02403 Seryl-tRNA synthetase N-terminal domain SIRE_RS07140 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SIRE_RS07145 PF01883 Iron-sulfur cluster assembly protein SIRE_RS07150 PF01502 Phosphoribosyl-AMP cyclohydrolase SIRE_RS07155 PF00117 Glutamine amidotransferase class-I SIRE_RS07160 PF01503 Phosphoribosyl-ATP pyrophosphohydrolase SIRE_RS07160 PF01502 Phosphoribosyl-AMP cyclohydrolase SIRE_RS07165 PF00815 Histidinol dehydrogenase SIRE_RS07170 PF00977 Histidine biosynthesis protein SIRE_RS07175 PF00475 Imidazoleglycerol-phosphate dehydratase SIRE_RS07180 PF00977 Histidine biosynthesis protein SIRE_RS07185 PF08029 HisG, C-terminal domain SIRE_RS07185 PF01634 ATP phosphoribosyltransferase SIRE_RS07190 PF00155 Aminotransferase class I and II SIRE_RS07200 PF08264 Anticodon-binding domain of tRNA SIRE_RS07200 PF00133 tRNA synthetases class I (I, L, M and V) SIRE_RS07200 PF13603 Leucyl-tRNA synthetase, Domain 2 SIRE_RS07200 PF09334 tRNA synthetases class I (M) SIRE_RS07205 PF01923 Cobalamin adenosyltransferase SIRE_RS07210 PF01171 PP-loop family SIRE_RS07220 PF02675 S-adenosylmethionine decarboxylase SIRE_RS07245 PF01926 50S ribosome-binding GTPase SIRE_RS07255 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SIRE_RS07255 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SIRE_RS07255 PF00205 Thiamine pyrophosphate enzyme, central domain SIRE_RS07265 PF01450 Acetohydroxy acid isomeroreductase, catalytic domain SIRE_RS07265 PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain SIRE_RS07280 PF01174 SNO glutamine amidotransferase family SIRE_RS07285 PF01680 SOR/SNZ family SIRE_RS07295 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SIRE_RS07295 PF09180 Prolyl-tRNA synthetase, C-terminal SIRE_RS07295 PF03129 Anticodon binding domain SIRE_RS07310 PF01813 ATP synthase subunit D SIRE_RS07315 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SIRE_RS07315 PF02874 ATP synthase alpha/beta family, beta-barrel domain SIRE_RS07320 PF16886 ATPsynthase alpha/beta subunit N-term extension SIRE_RS07320 PF02874 ATP synthase alpha/beta family, beta-barrel domain SIRE_RS07320 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SIRE_RS07340 PF08264 Anticodon-binding domain of tRNA SIRE_RS07340 PF09334 tRNA synthetases class I (M) SIRE_RS07370 PF03104 DNA polymerase family B, exonuclease domain SIRE_RS07370 PF00136 DNA polymerase family B SIRE_RS07385 PF05552 Conserved TM helix SIRE_RS07385 PF00924 Mechanosensitive ion channel SIRE_RS07395 PF00162 Phosphoglycerate kinase SIRE_RS07405 PF00582 Universal stress protein family SIRE_RS07410 PF00464 Serine hydroxymethyltransferase SIRE_RS07430 PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SIRE_RS07430 PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SIRE_RS07435 PF02675 S-adenosylmethionine decarboxylase SIRE_RS07600 PF01156 Inosine-uridine preferring nucleoside hydrolase SIRE_RS07605 PF13603 Leucyl-tRNA synthetase, Domain 2 SIRE_RS07605 PF09334 tRNA synthetases class I (M) SIRE_RS07605 PF00133 tRNA synthetases class I (I, L, M and V) SIRE_RS07605 PF08264 Anticodon-binding domain of tRNA SIRE_RS07655 PF03807 NADP oxidoreductase coenzyme F420-dependent SIRE_RS07655 PF14748 Pyrroline-5-carboxylate reductase dimerisation SIRE_RS07680 PF00291 Pyridoxal-phosphate dependent enzyme SIRE_RS07685 PF00005 ABC transporter SIRE_RS07690 PF00005 ABC transporter SIRE_RS07695 PF01032 FecCD transport family SIRE_RS07705 PF00902 Sec-independent protein translocase protein (TatC) SIRE_RS07715 PF02416 mttA/Hcf106 family SIRE_RS07720 PF13419 Haloacid dehalogenase-like hydrolase SIRE_RS07725 PF04055 Radical SAM superfamily SIRE_RS07725 PF00583 Acetyltransferase (GNAT) family SIRE_RS07725 PF16199 Radical_SAM C-terminal domain SIRE_RS07740 PF04055 Radical SAM superfamily SIRE_RS07740 PF01938 TRAM domain SIRE_RS07740 PF00919 Uncharacterized protein family UPF0004 SIRE_RS07750 PF17757 UvrB interaction domain SIRE_RS07750 PF00271 Helicase conserved C-terminal domain SIRE_RS07750 PF12344 Ultra-violet resistance protein B SIRE_RS07750 PF04851 Type III restriction enzyme, res subunit SIRE_RS07750 PF02151 UvrB/uvrC motif SIRE_RS07755 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS07755 PF00107 Zinc-binding dehydrogenase SIRE_RS07765 PF03144 Elongation factor Tu domain 2 SIRE_RS07765 PF09106 Elongation factor SelB, winged helix SIRE_RS07765 PF09107 Elongation factor SelB, winged helix SIRE_RS07765 PF00009 Elongation factor Tu GTP binding domain SIRE_RS07785 PF08543 Phosphomethylpyrimidine kinase SIRE_RS07785 PF10120 Thiamine-phosphate synthase SIRE_RS07790 PF03176 MMPL family SIRE_RS07815 PF10609 NUBPL iron-transfer P-loop NTPase SIRE_RS07835 PF01810 LysE type translocator SIRE_RS07850 PF00579 tRNA synthetases class I (W and Y) SIRE_RS07865 PF02272 DHHA1 domain SIRE_RS07865 PF01411 tRNA synthetases class II (A) SIRE_RS07865 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SIRE_RS07875 PF00155 Aminotransferase class I and II SIRE_RS07910 PF00491 Arginase family SIRE_RS07915 PF03129 Anticodon binding domain SIRE_RS07915 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SIRE_RS07945 PF02441 Flavoprotein SIRE_RS07960 PF00814 Glycoprotease family SIRE_RS07965 PF03793 PASTA domain SIRE_RS07965 PF00069 Protein kinase domain SIRE_RS07970 PF01725 Ham1 family SIRE_RS07975 PF00248 Aldo/keto reductase family SIRE_RS07995 PF08704 tRNA methyltransferase complex GCD14 subunit SIRE_RS08020 PF01131 DNA topoisomerase SIRE_RS08020 PF01751 Toprim domain SIRE_RS08020 PF17915 Reverse gyrase zinc finger SIRE_RS08020 PF00270 DEAD/DEAH box helicase SIRE_RS08025 PF01434 Peptidase family M41 SIRE_RS08025 PF17862 AAA+ lid domain SIRE_RS08025 PF00004 ATPase family associated with various cellular activities (AAA) SIRE_RS08030 PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase SIRE_RS08030 PF01676 Metalloenzyme superfamily SIRE_RS08045 PF00575 S1 RNA binding domain SIRE_RS08055 PF09106 Elongation factor SelB, winged helix SIRE_RS08055 PF09107 Elongation factor SelB, winged helix SIRE_RS08055 PF03144 Elongation factor Tu domain 2 SIRE_RS08055 PF09105 Elongation factor SelB, winged helix SIRE_RS08055 PF00009 Elongation factor Tu GTP binding domain SIRE_RS08065 PF01903 CbiX SIRE_RS08075 PF01717 Cobalamin-independent synthase, Catalytic domain SIRE_RS08075 PF08267 Cobalamin-independent synthase, N-terminal domain SIRE_RS08090 PF07685 CobB/CobQ-like glutamine amidotransferase domain SIRE_RS08090 PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain SIRE_RS08100 PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase SIRE_RS08100 PF00925 GTP cyclohydrolase II SIRE_RS08110 PF00885 6,7-dimethyl-8-ribityllumazine synthase SIRE_RS08120 PF01979 Amidohydrolase family SIRE_RS08135 PF00005 ABC transporter SIRE_RS08135 PF00664 ABC transporter transmembrane region SIRE_RS08140 PF08494 DEAD/H associated SIRE_RS08140 PF00270 DEAD/DEAH box helicase SIRE_RS08140 PF00271 Helicase conserved C-terminal domain SIRE_RS08150 PF01509 TruB family pseudouridylate synthase (N terminal domain) SIRE_RS08150 PF16198 tRNA pseudouridylate synthase B C-terminal domain SIRE_RS08155 PF01509 TruB family pseudouridylate synthase (N terminal domain) SIRE_RS08155 PF16198 tRNA pseudouridylate synthase B C-terminal domain SIRE_RS08160 PF08468 Methyltransferase small domain N-terminal SIRE_RS08160 PF05175 Methyltransferase small domain SIRE_RS08170 PF17176 tRNA-binding domain SIRE_RS08170 PF05127 Helicase SIRE_RS08170 PF08351 Domain of unknown function (DUF1726) SIRE_RS08170 PF13718 GNAT acetyltransferase 2 SIRE_RS08215 PF12706 Beta-lactamase superfamily domain SIRE_RS08215 PF07521 Zn-dependent metallo-hydrolase RNA specificity domain SIRE_RS08215 PF17770 Ribonuclease J C-terminal domain SIRE_RS08220 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SIRE_RS08220 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SIRE_RS08220 PF03129 Anticodon binding domain SIRE_RS08220 PF02824 TGS domain SIRE_RS08230 PF01380 SIS domain SIRE_RS08235 PF00483 Nucleotidyl transferase SIRE_RS08245 PF02423 Ornithine cyclodeaminase/mu-crystallin family SIRE_RS08255 PF00999 Sodium/hydrogen exchanger family SIRE_RS08260 PF02899 Phage integrase, N-terminal SAM-like domain SIRE_RS08260 PF00589 Phage integrase family SIRE_RS08265 PF04055 Radical SAM superfamily SIRE_RS08265 PF13186 Iron-sulfur cluster-binding domain SIRE_RS08270 PF00132 Bacterial transferase hexapeptide (six repeats) SIRE_RS08275 PF13636 RNA-binding PUA-like domain of methyltransferase RsmF SIRE_RS08275 PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF SIRE_RS08275 PF01189 16S rRNA methyltransferase RsmB/F SIRE_RS08285 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS08285 PF00501 AMP-binding enzyme SIRE_RS08290 PF00085 Thioredoxin SIRE_RS08295 PF00005 ABC transporter SIRE_RS08295 PF03459 TOBE domain SIRE_RS08300 PF03951 Glutamine synthetase, beta-Grasp domain SIRE_RS08300 PF00120 Glutamine synthetase, catalytic domain SIRE_RS08310 PF01227 GTP cyclohydrolase I SIRE_RS08315 PF01321 Creatinase/Prolidase N-terminal domain SIRE_RS08315 PF00557 Metallopeptidase family M24 SIRE_RS08320 PF06463 Molybdenum Cofactor Synthesis C SIRE_RS08320 PF04055 Radical SAM superfamily SIRE_RS08335 PF00291 Pyridoxal-phosphate dependent enzyme SIRE_RS08400 PF02881 SRP54-type protein, helical bundle domain SIRE_RS08400 PF00448 SRP54-type protein, GTPase domain SIRE_RS08415 PF00298 Ribosomal protein L11, RNA binding domain SIRE_RS08415 PF03946 Ribosomal protein L11, N-terminal domain SIRE_RS08425 PF00466 Ribosomal protein L10 SIRE_RS08435 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SIRE_RS08435 PF01411 tRNA synthetases class II (A) SIRE_RS08435 PF02272 DHHA1 domain SIRE_RS08465 PF02568 Thiamine biosynthesis protein (ThiI) SIRE_RS08465 PF02926 THUMP domain SIRE_RS08470 PF01658 Myo-inositol-1-phosphate synthase SIRE_RS08475 PF00361 Proton-conducting membrane transporter SIRE_RS08480 PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus SIRE_RS08480 PF00361 Proton-conducting membrane transporter SIRE_RS08485 PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L SIRE_RS08495 PF12838 4Fe-4S dicluster domain SIRE_RS08500 PF00146 NADH dehydrogenase SIRE_RS08505 PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit SIRE_RS08510 PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit SIRE_RS08520 PF02511 Thymidylate synthase complementing protein SIRE_RS08540 PF00483 Nucleotidyl transferase SIRE_RS08545 PF02777 Iron/manganese superoxide dismutases, C-terminal domain SIRE_RS08545 PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain SIRE_RS08585 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SIRE_RS08595 PF01264 Chorismate synthase SIRE_RS08600 PF08501 Shikimate dehydrogenase substrate binding domain SIRE_RS08600 PF01488 Shikimate / quinate 5-dehydrogenase SIRE_RS08600 PF18317 Shikimate 5'-dehydrogenase C-terminal domain SIRE_RS08605 PF01761 3-dehydroquinate synthase SIRE_RS08610 PF18152 DAHP synthase ferredoxin-like domain SIRE_RS08610 PF00793 DAHP synthetase I family SIRE_RS08615 PF01842 ACT domain SIRE_RS08615 PF01817 Chorismate mutase type II SIRE_RS08615 PF00800 Prephenate dehydratase SIRE_RS08620 PF02779 Transketolase, pyrimidine binding domain SIRE_RS08620 PF02780 Transketolase, C-terminal domain SIRE_RS08625 PF00456 Transketolase, thiamine diphosphate binding domain SIRE_RS08630 PF00899 ThiF family SIRE_RS08630 PF14461 Prokaryotic E2 family B SIRE_RS08650 PF00252 Ribosomal protein L16p/L10e SIRE_RS08660 PF00575 S1 RNA binding domain SIRE_RS08660 PF03725 3' exoribonuclease family, domain 2 SIRE_RS08660 PF01138 3' exoribonuclease family, domain 1 SIRE_RS08660 PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain SIRE_RS08660 PF00013 KH domain SIRE_RS08685 PF00083 Sugar (and other) transporter SIRE_RS08695 PF00005 ABC transporter SIRE_RS08700 PF01950 Fructose-1,6-bisphosphatase SIRE_RS08725 PF00118 TCP-1/cpn60 chaperonin family SIRE_RS08740 PF03129 Anticodon binding domain SIRE_RS08740 PF13393 Histidyl-tRNA synthetase SIRE_RS08775 PF00004 ATPase family associated with various cellular activities (AAA) SIRE_RS08775 PF01434 Peptidase family M41 SIRE_RS08775 PF06480 FtsH Extracellular SIRE_RS08775 PF17862 AAA+ lid domain SIRE_RS08785 PF01926 50S ribosome-binding GTPase SIRE_RS08785 PF13167 GTP-binding GTPase N-terminal SIRE_RS08785 PF16360 GTP-binding GTPase Middle Region SIRE_RS08800 PF00145 C-5 cytosine-specific DNA methylase SIRE_RS08825 PF01884 PcrB family SIRE_RS08860 PF00293 NUDIX domain SIRE_RS08860 PF01467 Cytidylyltransferase-like SIRE_RS08875 PF13636 RNA-binding PUA-like domain of methyltransferase RsmF SIRE_RS08875 PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF SIRE_RS08875 PF01189 16S rRNA methyltransferase RsmB/F SIRE_RS08890 PF01230 HIT domain SIRE_RS08895 PF00291 Pyridoxal-phosphate dependent enzyme SIRE_RS08900 PF00800 Prephenate dehydratase SIRE_RS08900 PF01817 Chorismate mutase type II SIRE_RS08900 PF01842 ACT domain SIRE_RS08905 PF17805 AsnC-like ligand binding domain SIRE_RS08905 PF13404 AsnC-type helix-turn-helix domain SIRE_RS08915 PF00709 Adenylosuccinate synthetase SIRE_RS08930 PF00206 Lyase SIRE_RS08930 PF10397 Adenylosuccinate lyase C-terminus SIRE_RS08945 PF04055 Radical SAM superfamily SIRE_RS08945 PF06463 Molybdenum Cofactor Synthesis C SIRE_RS08955 PF00156 Phosphoribosyl transferase domain SIRE_RS08960 PF02637 GatB domain SIRE_RS08960 PF02934 GatB/GatE catalytic domain SIRE_RS08980 PF00334 Nucleoside diphosphate kinase SIRE_RS08985 PF04760 Translation initiation factor IF-2, N-terminal region SIRE_RS08985 PF11987 Translation-initiation factor 2 SIRE_RS08985 PF00009 Elongation factor Tu GTP binding domain SIRE_RS08995 PF04561 RNA polymerase Rpb2, domain 2 SIRE_RS08995 PF04563 RNA polymerase beta subunit SIRE_RS08995 PF04565 RNA polymerase Rpb2, domain 3 SIRE_RS08995 PF10385 RNA polymerase beta subunit external 1 domain SIRE_RS08995 PF00562 RNA polymerase Rpb2, domain 6 SIRE_RS08995 PF04560 RNA polymerase Rpb2, domain 7 SIRE_RS09000 PF04998 RNA polymerase Rpb1, domain 5 SIRE_RS09000 PF05000 RNA polymerase Rpb1, domain 4 SIRE_RS09000 PF04983 RNA polymerase Rpb1, domain 3 SIRE_RS09000 PF00623 RNA polymerase Rpb1, domain 2 SIRE_RS09000 PF04997 RNA polymerase Rpb1, domain 1 SIRE_RS09005 PF04997 RNA polymerase Rpb1, domain 1 SIRE_RS09005 PF00623 RNA polymerase Rpb1, domain 2 SIRE_RS09005 PF04983 RNA polymerase Rpb1, domain 3 SIRE_RS09005 PF05000 RNA polymerase Rpb1, domain 4 SIRE_RS09005 PF04998 RNA polymerase Rpb1, domain 5 SIRE_RS09030 PF00177 Ribosomal protein S7p/S5e SIRE_RS09035 PF00009 Elongation factor Tu GTP binding domain SIRE_RS09035 PF03144 Elongation factor Tu domain 2 SIRE_RS09035 PF03143 Elongation factor Tu C-terminal domain SIRE_RS09040 PF00338 Ribosomal protein S10p/S20e SIRE_RS09080 PF00583 Acetyltransferase (GNAT) family SIRE_RS09085 PF04127 DNA / pantothenate metabolism flavoprotein SIRE_RS09085 PF02441 Flavoprotein SIRE_RS09115 PF00326 Prolyl oligopeptidase family SIRE_RS09115 PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region SIRE_RS09160 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SIRE_RS09160 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SIRE_RS09160 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SIRE_RS09160 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain SIRE_RS09180 PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family SIRE_RS09185 PF00117 Glutamine amidotransferase class-I SIRE_RS09185 PF06418 CTP synthase N-terminus SIRE_RS09200 PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) SIRE_RS09230 PF01871 AMMECR1 SIRE_RS09245 PF00692 dUTPase SIRE_RS09250 PF04679 ATP dependent DNA ligase C terminal region SIRE_RS09250 PF01068 ATP dependent DNA ligase domain SIRE_RS09250 PF04675 DNA ligase N terminus SIRE_RS09255 PF04675 DNA ligase N terminus SIRE_RS09255 PF04679 ATP dependent DNA ligase C terminal region SIRE_RS09255 PF01068 ATP dependent DNA ligase domain SIRE_RS09260 PF01266 FAD dependent oxidoreductase SIRE_RS09285 PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain SIRE_RS09285 PF03900 Porphobilinogen deaminase, C-terminal domain SIRE_RS09290 PF00202 Aminotransferase class-III SIRE_RS09295 PF00490 Delta-aminolevulinic acid dehydratase SIRE_RS09300 PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain SIRE_RS09300 PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain SIRE_RS09300 PF01488 Shikimate / quinate 5-dehydrogenase SIRE_RS09305 PF10414 Sirohaem synthase dimerisation region SIRE_RS09305 PF14824 Sirohaem biosynthesis protein central SIRE_RS09305 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SIRE_RS09320 PF01434 Peptidase family M41 SIRE_RS09320 PF00004 ATPase family associated with various cellular activities (AAA) SIRE_RS09320 PF17862 AAA+ lid domain SIRE_RS09320 PF06480 FtsH Extracellular SIRE_RS09340 PF01142 tRNA pseudouridine synthase D (TruD) SIRE_RS09345 PF01336 OB-fold nucleic acid binding domain SIRE_RS09345 PF00152 tRNA synthetases class II (D, K and N) SIRE_RS09360 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SIRE_RS09360 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SIRE_RS09360 PF00205 Thiamine pyrophosphate enzyme, central domain SIRE_RS09375 PF00005 ABC transporter SIRE_RS09390 PF01370 NAD dependent epimerase/dehydratase family SIRE_RS09405 PF01255 Putative undecaprenyl diphosphate synthase SIRE_RS09410 PF01546 Peptidase family M20/M25/M40 SIRE_RS09415 PF00202 Aminotransferase class-III SIRE_RS09420 PF08443 RimK-like ATP-grasp domain SIRE_RS09435 PF00696 Amino acid kinase family SIRE_RS09440 PF01118 Semialdehyde dehydrogenase, NAD binding domain SIRE_RS09440 PF02774 Semialdehyde dehydrogenase, dimerisation domain SIRE_RS09455 PF01380 SIS domain SIRE_RS09500 PF03600 Citrate transporter SIRE_RS09535 PF08502 LeuA allosteric (dimerisation) domain SIRE_RS09535 PF00682 HMGL-like SIRE_RS09540 PF01040 UbiA prenyltransferase family SIRE_RS09555 PF01189 16S rRNA methyltransferase RsmB/F SIRE_RS09555 PF01029 NusB family SIRE_RS09565 PF00437 Type II/IV secretion system protein SIRE_RS09590 PF10576 Iron-sulfur binding domain of endonuclease III SIRE_RS09590 PF00633 Helix-hairpin-helix motif SIRE_RS09590 PF00730 HhH-GPD superfamily base excision DNA repair protein SIRE_RS09605 PF00270 DEAD/DEAH box helicase SIRE_RS09605 PF00271 Helicase conserved C-terminal domain SIRE_RS09605 PF08494 DEAD/H associated SIRE_RS09610 PF00571 CBS domain SIRE_RS09610 PF01743 Poly A polymerase head domain SIRE_RS09635 PF00155 Aminotransferase class I and II SIRE_RS09640 PF18146 Damage-inducible protein CinA KH domain SIRE_RS09640 PF02464 Competence-damaged protein SIRE_RS09640 PF00994 Probable molybdopterin binding domain SIRE_RS09645 PF12697 Alpha/beta hydrolase family SIRE_RS09650 PF03484 tRNA synthetase B5 domain SIRE_RS09650 PF17759 Phenylalanyl tRNA synthetase beta chain CLM domain SIRE_RS09655 PF01409 tRNA synthetases class II core domain (F) SIRE_RS09685 PF01966 HD domain SIRE_RS09695 PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain SIRE_RS09695 PF00749 tRNA synthetases class I (E and Q), catalytic domain SIRE_RS09710 PF01336 OB-fold nucleic acid binding domain SIRE_RS09710 PF00152 tRNA synthetases class II (D, K and N) SIRE_RS09740 PF00814 Glycoprotease family SIRE_RS09740 PF00583 Acetyltransferase (GNAT) family SIRE_RS09755 PF00579 tRNA synthetases class I (W and Y) SIRE_RS09770 PF00416 Ribosomal protein S13/S18 SIRE_RS09775 PF00163 Ribosomal protein S4/S9 N-terminal domain SIRE_RS09775 PF01479 S4 domain SIRE_RS09780 PF00411 Ribosomal protein S11 SIRE_RS09790 PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SIRE_RS09795 PF00572 Ribosomal protein L13 SIRE_RS09800 PF00380 Ribosomal protein S9/S16 SIRE_RS09810 PF00318 Ribosomal protein S2 SIRE_RS09815 PF01875 Memo-like protein SIRE_RS09830 PF01070 FMN-dependent dehydrogenase SIRE_RS09835 PF00348 Polyprenyl synthetase SIRE_RS09840 PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 SIRE_RS09840 PF00953 Glycosyl transferase family 4 SIRE_RS09925 PF00005 ABC transporter SIRE_RS09955 PF01026 TatD related DNase SIRE_RS09970 PF00115 Cytochrome C and Quinol oxidase polypeptide I SIRE_RS10010 PF13614 AAA domain SIRE_RS10025 PF00795 Carbon-nitrogen hydrolase SIRE_RS10030 PF12627 Probable RNA and SrmB- binding site of polymerase A SIRE_RS10030 PF01743 Poly A polymerase head domain SIRE_RS10030 PF01368 DHH family SIRE_RS10030 PF00571 CBS domain SIRE_RS10030 PF02272 DHHA1 domain SIRE_RS10035 PF00850 Histone deacetylase domain SIRE_RS10040 PF02222 ATP-grasp domain SIRE_RS10075 PF00994 Probable molybdopterin binding domain SIRE_RS10085 PF00271 Helicase conserved C-terminal domain SIRE_RS10085 PF00270 DEAD/DEAH box helicase SIRE_RS10085 PF08494 DEAD/H associated SIRE_RS10095 PF06508 Queuosine biosynthesis protein QueC SIRE_RS10120 PF03458 UPF0126 domain SIRE_RS10130 PF01321 Creatinase/Prolidase N-terminal domain SIRE_RS10130 PF00557 Metallopeptidase family M24 SIRE_RS10135 PF00850 Histone deacetylase domain SIRE_RS10155 PF00294 pfkB family carbohydrate kinase SIRE_RS10160 PF02581 Thiamine monophosphate synthase SIRE_RS10160 PF08543 Phosphomethylpyrimidine kinase SIRE_RS10205 PF00155 Aminotransferase class I and II SIRE_RS10205 PF00392 Bacterial regulatory proteins, gntR family SIRE_RS10220 PF00535 Glycosyl transferase family 2 SIRE_RS10230 PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain SIRE_RS10230 PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase SIRE_RS10240 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS10240 PF00107 Zinc-binding dehydrogenase SIRE_RS10245 PF03186 CobD/Cbib protein SIRE_RS10245 PF17113 Regulatory signalling modulator protein AmpE SIRE_RS10250 PF02654 Cobalamin-5-phosphate synthase SIRE_RS10255 PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain SIRE_RS10255 PF07685 CobB/CobQ-like glutamine amidotransferase domain SIRE_RS10260 PF02540 NAD synthase SIRE_RS10260 PF00117 Glutamine amidotransferase class-I SIRE_RS10260 PF00958 GMP synthase C terminal domain SIRE_RS10265 PF01435 Peptidase family M48 SIRE_RS10270 PF00478 IMP dehydrogenase / GMP reductase domain SIRE_RS10270 PF00571 CBS domain SIRE_RS10280 PF01791 DeoC/LacD family aldolase SIRE_RS10295 PF00483 Nucleotidyl transferase SIRE_RS10320 PF13718 GNAT acetyltransferase 2 SIRE_RS10320 PF08351 Domain of unknown function (DUF1726) SIRE_RS10320 PF17176 tRNA-binding domain SIRE_RS10320 PF05127 Helicase SIRE_RS10335 PF00202 Aminotransferase class-III SIRE_RS10340 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SIRE_RS10340 PF00205 Thiamine pyrophosphate enzyme, central domain SIRE_RS10340 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SIRE_RS10345 PF00248 Aldo/keto reductase family SIRE_RS10360 PF01042 Endoribonuclease L-PSP SIRE_RS10365 PF01743 Poly A polymerase head domain SIRE_RS10365 PF00571 CBS domain SIRE_RS10370 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS10370 PF00107 Zinc-binding dehydrogenase SIRE_RS10375 PF16177 Acetyl-coenzyme A synthetase N-terminus SIRE_RS10375 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS10375 PF00501 AMP-binding enzyme SIRE_RS10385 PF00174 Oxidoreductase molybdopterin binding domain SIRE_RS10395 PF13378 Enolase C-terminal domain-like SIRE_RS10395 PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SIRE_RS10400 PF00701 Dihydrodipicolinate synthetase family SIRE_RS10405 PF00294 pfkB family carbohydrate kinase SIRE_RS10410 PF00171 Aldehyde dehydrogenase family SIRE_RS10420 PF00384 Molybdopterin oxidoreductase SIRE_RS10420 PF18364 Molybdopterin oxidoreductase N-terminal domain SIRE_RS10420 PF01568 Molydopterin dinucleotide binding domain SIRE_RS10465 PF00324 Amino acid permease SIRE_RS10470 PF00582 Universal stress protein family SIRE_RS10475 PF00069 Protein kinase domain SIRE_RS10475 PF03793 PASTA domain SIRE_RS10485 PF00083 Sugar (and other) transporter SIRE_RS10570 PF01638 HxlR-like helix-turn-helix SIRE_RS10580 PF00478 IMP dehydrogenase / GMP reductase domain SIRE_RS10580 PF00571 CBS domain SIRE_RS10585 PF18389 TrmO C-terminal domain SIRE_RS10585 PF01980 tRNA-methyltransferase O SIRE_RS10590 PF13732 Domain of unknown function (DUF4162) SIRE_RS10590 PF00005 ABC transporter SIRE_RS10630 PF02913 FAD linked oxidases, C-terminal domain SIRE_RS10630 PF01565 FAD binding domain SIRE_RS10635 PF02754 Cysteine-rich domain SIRE_RS10635 PF13183 4Fe-4S dicluster domain SIRE_RS10640 PF03099 Biotin/lipoate A/B protein ligase family SIRE_RS10645 PF04055 Radical SAM superfamily SIRE_RS10645 PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family SIRE_RS10655 PF10437 Bacterial lipoate protein ligase C-terminus SIRE_RS10655 PF03099 Biotin/lipoate A/B protein ligase family SIRE_RS10660 PF03358 NADPH-dependent FMN reductase SIRE_RS10680 PF07992 Pyridine nucleotide-disulphide oxidoreductase SIRE_RS10680 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SIRE_RS10685 PF07690 Major Facilitator Superfamily SIRE_RS10710 PF02515 CoA-transferase family III SIRE_RS10715 PF00083 Sugar (and other) transporter SIRE_RS10745 PF07977 FabA-like domain SIRE_RS10765 PF00753 Metallo-beta-lactamase superfamily SIRE_RS10775 PF11870 Domain of unknown function (DUF3390) SIRE_RS10775 PF02589 LUD domain SIRE_RS10775 PF13183 4Fe-4S dicluster domain SIRE_RS10780 PF07690 Major Facilitator Superfamily SIRE_RS10795 PF01966 HD domain SIRE_RS10800 PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SIRE_RS10800 PF13378 Enolase C-terminal domain-like SIRE_RS10810 PF07690 Major Facilitator Superfamily SIRE_RS10810 PF00083 Sugar (and other) transporter SIRE_RS10815 PF00083 Sugar (and other) transporter SIRE_RS10820 PF01557 Fumarylacetoacetate (FAA) hydrolase family SIRE_RS10825 PF00171 Aldehyde dehydrogenase family SIRE_RS10830 PF00561 alpha/beta hydrolase fold SIRE_RS10870 PF00902 Sec-independent protein translocase protein (TatC) SIRE_RS10880 PF00920 Dehydratase family SIRE_RS10885 PF02074 Carboxypeptidase Taq (M32) metallopeptidase SIRE_RS10935 PF00005 ABC transporter SIRE_RS10975 PF01206 Sulfurtransferase TusA SIRE_RS10995 PF00005 ABC transporter SIRE_RS11020 PF07690 Major Facilitator Superfamily SIRE_RS11060 PF00701 Dihydrodipicolinate synthetase family SIRE_RS11070 PF00005 ABC transporter SIRE_RS11070 PF03459 TOBE domain SIRE_RS11070 PF17912 MalK OB fold domain SIRE_RS11075 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS11080 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS11090 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS11090 PF00501 AMP-binding enzyme SIRE_RS11110 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS11120 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SIRE_RS11120 PF00005 ABC transporter SIRE_RS11125 PF00248 Aldo/keto reductase family SIRE_RS11135 PF13472 GDSL-like Lipase/Acylhydrolase family SIRE_RS11140 PF16338 Domain of unknown function (DUF4968) SIRE_RS11140 PF17137 Domain of unknown function (DUF5110) SIRE_RS11140 PF13802 Galactose mutarotase-like SIRE_RS11140 PF01055 Glycosyl hydrolases family 31 SIRE_RS11150 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SIRE_RS11150 PF02894 Oxidoreductase family, C-terminal alpha/beta domain SIRE_RS11155 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS11160 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS11165 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SIRE_RS11165 PF00005 ABC transporter SIRE_RS11170 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SIRE_RS11170 PF00005 ABC transporter SIRE_RS11175 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle SIRE_RS11180 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS11180 PF00107 Zinc-binding dehydrogenase SIRE_RS11185 PF08450 SMP-30/Gluconolactonase/LRE-like region SIRE_RS11200 PF02837 Glycosyl hydrolases family 2, sugar binding domain SIRE_RS11200 PF00703 Glycosyl hydrolases family 2 SIRE_RS11200 PF02836 Glycosyl hydrolases family 2, TIM barrel domain SIRE_RS11205 PF00701 Dihydrodipicolinate synthetase family SIRE_RS11210 PF14310 Fibronectin type III-like domain SIRE_RS11210 PF00933 Glycosyl hydrolase family 3 N terminal domain SIRE_RS11210 PF01915 Glycosyl hydrolase family 3 C-terminal domain SIRE_RS11260 PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain SIRE_RS11260 PF08531 Alpha-L-rhamnosidase N-terminal domain SIRE_RS11260 PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain SIRE_RS11260 PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain SIRE_RS11285 PF16338 Domain of unknown function (DUF4968) SIRE_RS11285 PF17137 Domain of unknown function (DUF5110) SIRE_RS11285 PF01055 Glycosyl hydrolases family 31 SIRE_RS11295 PF00232 Glycosyl hydrolase family 1 SIRE_RS11315 PF00248 Aldo/keto reductase family SIRE_RS11320 PF02894 Oxidoreductase family, C-terminal alpha/beta domain SIRE_RS11320 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SIRE_RS11325 PF00664 ABC transporter transmembrane region SIRE_RS11325 PF00005 ABC transporter SIRE_RS11330 PF02894 Oxidoreductase family, C-terminal alpha/beta domain SIRE_RS11330 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SIRE_RS11340 PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase SIRE_RS11340 PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain SIRE_RS11345 PF02894 Oxidoreductase family, C-terminal alpha/beta domain SIRE_RS11345 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SIRE_RS11390 PF00118 TCP-1/cpn60 chaperonin family SIRE_RS11395 PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SIRE_RS11395 PF13378 Enolase C-terminal domain-like SIRE_RS11400 PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SIRE_RS11400 PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SIRE_RS11405 PF01566 Natural resistance-associated macrophage protein SIRE_RS11480 PF01008 Initiation factor 2 subunit family SIRE_RS11500 PF00115 Cytochrome C and Quinol oxidase polypeptide I SIRE_RS11515 PF02167 Cytochrome C1 family SIRE_RS11515 PF00032 Cytochrome b(C-terminal)/b6/petD SIRE_RS11515 PF00033 Cytochrome b/b6/petB SIRE_RS11575 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS11580 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS11580 PF12911 N-terminal TM domain of oligopeptide transport permease C SIRE_RS11585 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SIRE_RS11585 PF00005 ABC transporter SIRE_RS11590 PF00005 ABC transporter SIRE_RS11590 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SIRE_RS11675 PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase SIRE_RS11675 PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain SIRE_RS11680 PF01557 Fumarylacetoacetate (FAA) hydrolase family SIRE_RS11690 PF05378 Hydantoinase/oxoprolinase N-terminal region SIRE_RS11690 PF01968 Hydantoinase/oxoprolinase SIRE_RS11695 PF02538 Hydantoinase B/oxoprolinase SIRE_RS11720 PF01747 ATP-sulfurylase SIRE_RS11720 PF14306 PUA-like domain SIRE_RS11725 PF01507 Phosphoadenosine phosphosulfate reductase family SIRE_RS11730 PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain SIRE_RS11730 PF01077 Nitrite and sulphite reductase 4Fe-4S domain SIRE_RS11735 PF10414 Sirohaem synthase dimerisation region SIRE_RS11735 PF14824 Sirohaem biosynthesis protein central SIRE_RS11735 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SIRE_RS11740 PF00581 Rhodanese-like domain SIRE_RS11760 PF00753 Metallo-beta-lactamase superfamily SIRE_RS11760 PF16123 Hydroxyacylglutathione hydrolase C-terminus SIRE_RS11770 PF00248 Aldo/keto reductase family SIRE_RS11790 PF13478 XdhC Rossmann domain SIRE_RS11790 PF02625 XdhC and CoxI family SIRE_RS11795 PF00107 Zinc-binding dehydrogenase SIRE_RS11795 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS11800 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SIRE_RS11800 PF02770 Acyl-CoA dehydrogenase, middle domain SIRE_RS11800 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SIRE_RS11805 PF00501 AMP-binding enzyme SIRE_RS11805 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS11810 PF00108 Thiolase, N-terminal domain SIRE_RS11810 PF02803 Thiolase, C-terminal domain SIRE_RS11820 PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SIRE_RS11820 PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SIRE_RS11830 PF03949 Malic enzyme, NAD binding domain SIRE_RS11830 PF00390 Malic enzyme, N-terminal domain SIRE_RS11855 PF01184 GPR1/FUN34/yaaH family SIRE_RS11860 PF00501 AMP-binding enzyme SIRE_RS11860 PF16177 Acetyl-coenzyme A synthetase N-terminus SIRE_RS11860 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS11895 PF00083 Sugar (and other) transporter SIRE_RS11895 PF07690 Major Facilitator Superfamily SIRE_RS11905 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS11930 PF02633 Creatinine amidohydrolase SIRE_RS11940 PF00491 Arginase family SIRE_RS11945 PF03167 Uracil DNA glycosylase superfamily SIRE_RS11970 PF01546 Peptidase family M20/M25/M40 SIRE_RS11970 PF07687 Peptidase dimerisation domain SIRE_RS11975 PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal SIRE_RS11975 PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal SIRE_RS11980 PF00571 CBS domain SIRE_RS11990 PF00723 Glycosyl hydrolases family 15 SIRE_RS12045 PF00723 Glycosyl hydrolases family 15 SIRE_RS12050 PF00534 Glycosyl transferases group 1 SIRE_RS12050 PF13439 Glycosyltransferase Family 4 SIRE_RS12055 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SIRE_RS12060 PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg SIRE_RS12060 PF17147 Pyruvate:ferredoxin oxidoreductase core domain II SIRE_RS12070 PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase SIRE_RS12075 PF12800 4Fe-4S binding domain SIRE_RS12075 PF13247 4Fe-4S dicluster domain SIRE_RS12085 PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase SIRE_RS12085 PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain SIRE_RS12090 PF02771 Acyl-CoA dehydrogenase, N-terminal domain SIRE_RS12090 PF02770 Acyl-CoA dehydrogenase, middle domain SIRE_RS12090 PF00441 Acyl-CoA dehydrogenase, C-terminal domain SIRE_RS12095 PF01012 Electron transfer flavoprotein domain SIRE_RS12095 PF00766 Electron transfer flavoprotein FAD-binding domain SIRE_RS12100 PF01012 Electron transfer flavoprotein domain SIRE_RS12110 PF07992 Pyridine nucleotide-disulphide oxidoreductase SIRE_RS12130 PF07969 Amidohydrolase family SIRE_RS12140 PF01557 Fumarylacetoacetate (FAA) hydrolase family SIRE_RS12145 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SIRE_RS12145 PF00205 Thiamine pyrophosphate enzyme, central domain SIRE_RS12145 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SIRE_RS12150 PF13439 Glycosyltransferase Family 4 SIRE_RS12150 PF00534 Glycosyl transferases group 1 SIRE_RS12160 PF01494 FAD binding domain SIRE_RS12170 PF00582 Universal stress protein family SIRE_RS12175 PF00248 Aldo/keto reductase family SIRE_RS12180 PF00676 Dehydrogenase E1 component SIRE_RS12185 PF02779 Transketolase, pyrimidine binding domain SIRE_RS12185 PF02780 Transketolase, C-terminal domain SIRE_RS12210 PF09335 SNARE associated Golgi protein SIRE_RS12215 PF05552 Conserved TM helix SIRE_RS12215 PF00924 Mechanosensitive ion channel SIRE_RS12250 PF05506 Domain of unknown function (DUF756) SIRE_RS12250 PF04185 Phosphoesterase family SIRE_RS12275 PF13247 4Fe-4S dicluster domain SIRE_RS12275 PF12800 4Fe-4S binding domain SIRE_RS12280 PF04879 Molybdopterin oxidoreductase Fe4S4 domain SIRE_RS12280 PF00384 Molybdopterin oxidoreductase SIRE_RS12280 PF01568 Molydopterin dinucleotide binding domain SIRE_RS12305 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS12305 PF00107 Zinc-binding dehydrogenase SIRE_RS12345 PF00032 Cytochrome b(C-terminal)/b6/petD SIRE_RS12345 PF00033 Cytochrome b/b6/petB SIRE_RS12395 PF13193 AMP-binding enzyme C-terminal domain SIRE_RS12395 PF00501 AMP-binding enzyme SIRE_RS12400 PF03069 Acetamidase/Formamidase family SIRE_RS12420 PF17147 Pyruvate:ferredoxin oxidoreductase core domain II SIRE_RS12420 PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase SIRE_RS12420 PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg SIRE_RS12425 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SIRE_RS12430 PF01012 Electron transfer flavoprotein domain SIRE_RS12430 PF00766 Electron transfer flavoprotein FAD-binding domain SIRE_RS12445 PF00391 PEP-utilising enzyme, mobile domain SIRE_RS12445 PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain SIRE_RS12450 PF02634 FdhD/NarQ family SIRE_RS12460 PF12838 4Fe-4S dicluster domain SIRE_RS12460 PF00384 Molybdopterin oxidoreductase SIRE_RS12460 PF01568 Molydopterin dinucleotide binding domain SIRE_RS12460 PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region SIRE_RS12460 PF04879 Molybdopterin oxidoreductase Fe4S4 domain SIRE_RS12500 PF01434 Peptidase family M41 SIRE_RS12500 PF00004 ATPase family associated with various cellular activities (AAA) SIRE_RS12500 PF17862 AAA+ lid domain SIRE_RS12500 PF06480 FtsH Extracellular SIRE_RS12510 PF12323 Helix-turn-helix domain SIRE_RS12510 PF01385 Probable transposase SIRE_RS12510 PF07282 Putative transposase DNA-binding domain SIRE_RS12520 PF00202 Aminotransferase class-III SIRE_RS12535 PF00202 Aminotransferase class-III SIRE_RS12540 PF01546 Peptidase family M20/M25/M40 SIRE_RS12540 PF07687 Peptidase dimerisation domain SIRE_RS12550 PF07690 Major Facilitator Superfamily SIRE_RS12555 PF08240 Alcohol dehydrogenase GroES-like domain SIRE_RS12555 PF00107 Zinc-binding dehydrogenase SIRE_RS12560 PF07690 Major Facilitator Superfamily SIRE_RS12565 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS12570 PF00005 ABC transporter SIRE_RS12600 PF01048 Phosphorylase superfamily SIRE_RS12605 PF08450 SMP-30/Gluconolactonase/LRE-like region SIRE_RS12610 PF07690 Major Facilitator Superfamily SIRE_RS12635 PF03070 TENA/THI-4/PQQC family SIRE_RS12670 PF01435 Peptidase family M48 SIRE_RS12675 PF07676 WD40-like Beta Propeller Repeat SIRE_RS12675 PF00326 Prolyl oligopeptidase family SIRE_RS12690 PF07992 Pyridine nucleotide-disulphide oxidoreductase SIRE_RS12690 PF00403 Heavy-metal-associated domain SIRE_RS12690 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SIRE_RS12700 PF01022 Bacterial regulatory protein, arsR family SIRE_RS12765 PF06508 Queuosine biosynthesis protein QueC SIRE_RS12800 PF11838 ERAP1-like C-terminal domain SIRE_RS12800 PF01433 Peptidase family M1 domain SIRE_RS12810 PF01979 Amidohydrolase family SIRE_RS12815 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SIRE_RS12815 PF00005 ABC transporter SIRE_RS12820 PF00005 ABC transporter SIRE_RS12820 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SIRE_RS12825 PF12911 N-terminal TM domain of oligopeptide transport permease C SIRE_RS12825 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS12835 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS12850 PF13378 Enolase C-terminal domain-like SIRE_RS12850 PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SIRE_RS12875 PF00355 Rieske [2Fe-2S] domain SIRE_RS12885 PF00115 Cytochrome C and Quinol oxidase polypeptide I SIRE_RS12890 PF00033 Cytochrome b/b6/petB SIRE_RS12900 PF01569 PAP2 superfamily SIRE_RS12910 PF00403 Heavy-metal-associated domain SIRE_RS12920 PF00005 ABC transporter SIRE_RS12945 PF02915 Rubrerythrin SIRE_RS12960 PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase SIRE_RS12960 PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain SIRE_RS12965 PF01799 [2Fe-2S] binding domain SIRE_RS12965 PF00111 2Fe-2S iron-sulfur cluster binding domain SIRE_RS12970 PF03450 CO dehydrogenase flavoprotein C-terminal domain SIRE_RS12970 PF00941 FAD binding domain in molybdopterin dehydrogenase SIRE_RS12980 PF00581 Rhodanese-like domain SIRE_RS13020 PF00501 AMP-binding enzyme SIRE_RS13020 PF14535 AMP-binding enzyme C-terminal domain SIRE_RS13030 PF00108 Thiolase, N-terminal domain SIRE_RS13030 PF02803 Thiolase, C-terminal domain SIRE_RS13035 PF00378 Enoyl-CoA hydratase/isomerase SIRE_RS13040 PF00378 Enoyl-CoA hydratase/isomerase SIRE_RS13065 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS13070 PF00528 Binding-protein-dependent transport system inner membrane component SIRE_RS13070 PF12911 N-terminal TM domain of oligopeptide transport permease C SIRE_RS13075 PF00005 ABC transporter SIRE_RS13075 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SIRE_RS13080 PF00005 ABC transporter SIRE_RS13080 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SIRE_RS13090 PF00578 AhpC/TSA family SIRE_RS13095 PF13180 PDZ domain SIRE_RS13110 PF00534 Glycosyl transferases group 1 SIRE_RS13130 PF03109 ABC1 family SIRE_RS13160 PF00005 ABC transporter SIRE_RS13160 PF13732 Domain of unknown function (DUF4162) SIRE_RS13170 PF03070 TENA/THI-4/PQQC family SIRE_RS13175 PF00266 Aminotransferase class-V SIRE_RS13195 PF07282 Putative transposase DNA-binding domain SIRE_RS13195 PF01385 Probable transposase SIRE_RS13195 PF12323 Helix-turn-helix domain SIRE_RS13205 PF00121 Triosephosphate isomerase SIRE_RS13220 PF00285 Citrate synthase, C-terminal domain SIRE_RS13225 PF00571 CBS domain SIRE_RS13225 PF00478 IMP dehydrogenase / GMP reductase domain SIRE_RS13235 PF03972 MmgE/PrpD family SIRE_RS13240 PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain SIRE_RS13240 PF00056 lactate/malate dehydrogenase, NAD binding domain SIRE_RS13245 PF16363 GDP-mannose 4,6 dehydratase SIRE_RS13275 PF02163 Peptidase family M50 SIRE_RS13275 PF17820 PDZ domain SIRE_RS13295 PF03749 Sugar fermentation stimulation protein RE domain SIRE_RS13295 PF17746 SfsA N-terminal OB domain SIRE_RS13325 PF00881 Nitroreductase family SIRE_RS13330 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SIRE_RS13330 PF07992 Pyridine nucleotide-disulphide oxidoreductase SIRE_RS13335 PF07690 Major Facilitator Superfamily SIRE_RS13350 PF03951 Glutamine synthetase, beta-Grasp domain SIRE_RS13350 PF00120 Glutamine synthetase, catalytic domain SIRE_RS13365 PF00082 Subtilase family SIRE_RS13365 PF09286 Pro-kumamolisin, activation domain SIRE_RS13445 PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase SIRE_RS13445 PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain SIRE_RS13460 PF11838 ERAP1-like C-terminal domain SIRE_RS13460 PF01433 Peptidase family M1 domain SIRE_RS13485 PF13419 Haloacid dehalogenase-like hydrolase SIRE_RS13505 PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain SIRE_RS13505 PF01565 FAD binding domain SIRE_RS13510 PF01230 HIT domain SIRE_RS13535 PF00293 NUDIX domain SIRE_RS13545 PF06778 Chlorite dismutase SIRE_RS13555 PF03266 NTPase SIRE_RS13560 PF02540 NAD synthase SIRE_RS13590 PF13649 Methyltransferase domain SIRE_RS13595 PF02774 Semialdehyde dehydrogenase, dimerisation domain SIRE_RS13595 PF01118 Semialdehyde dehydrogenase, NAD binding domain SIRE_RS13610 PF04151 Bacterial pre-peptidase C-terminal domain SIRE_RS13610 PF09286 Pro-kumamolisin, activation domain SIRE_RS13615 PF00180 Isocitrate/isopropylmalate dehydrogenase SIRE_RS13765 PF01841 Transglutaminase-like superfamily SIRE_RS13765 PF08379 Bacterial transglutaminase-like N-terminal region SIRE_RS13905 PF00535 Glycosyl transferase family 2 SIRE_RS13980 PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) SIRE_RS14185 PF00005 ABC transporter SIRE_RS14185 PF13732 Domain of unknown function (DUF4162)