locus-tag	class	description
YN1551_RS00020	COG2154	pterin-4-alpha-carbinolamine dehydratase
YN1551_RS00100	COG1331	Highly conserved protein containing a thioredoxin domain
YN1551_RS00110	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
YN1551_RS00120	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
YN1551_RS00145	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
YN1551_RS00160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YN1551_RS00170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YN1551_RS00175	COG2814	Major facilitator Superfamily
YN1551_RS00185	COG0492	ferredoxin-NADP+ reductase activity
YN1551_RS00255	COG0588	phosphoglycerate mutase activity
YN1551_RS00275	COG1957	nucleoside hydrolase
YN1551_RS00325	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YN1551_RS00325	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YN1551_RS00330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YN1551_RS00335	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
YN1551_RS00355	COG0596	Alpha beta hydrolase
YN1551_RS00370	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YN1551_RS00410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YN1551_RS00415	COG1573	uracil-dna glycosylase
YN1551_RS00420	COG1028	Short-chain dehydrogenase reductase Sdr
YN1551_RS00445	COG0215	cysteine-tRNA ligase activity
YN1551_RS00450	COG2222	sugar isomerase
YN1551_RS00460	COG0446	pyridine nucleotide-disulphide oxidoreductase
YN1551_RS00470	COG0433	COG0433 Predicted ATPase
YN1551_RS00480	COG1607	acyl-coa hydrolase
YN1551_RS00490	COG1028	Short-chain dehydrogenase reductase Sdr
YN1551_RS00495	COG0708	Exodeoxyribonuclease III
YN1551_RS00535	COG1648	precorrin-2 dehydrogenase activity
YN1551_RS00535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YN1551_RS00545	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
YN1551_RS00565	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS00585	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS00590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YN1551_RS00670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YN1551_RS00680	COG0517	IMP dehydrogenase activity
YN1551_RS00680	COG0617	tRNA 3'-terminal CCA addition
YN1551_RS00680	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
YN1551_RS00690	COG3387	PFAM Glycoside hydrolase 15-related
YN1551_RS00735	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS00760	COG3387	PFAM Glycoside hydrolase 15-related
YN1551_RS00765	COG0438	transferase activity, transferring glycosyl groups
YN1551_RS00770	COG1013	pyruvate-flavodoxin oxidoreductase activity
YN1551_RS00775	COG0674	pyruvate-flavodoxin oxidoreductase activity
YN1551_RS00780	COG1144	Oxidoreductase
YN1551_RS00785	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YN1551_RS00790	COG0437	4 iron, 4 sulfur cluster binding
YN1551_RS00805	COG1960	acyl-CoA dehydrogenase activity
YN1551_RS00815	COG2086	electron transfer activity
YN1551_RS00825	COG0492	ferredoxin-NADP+ reductase activity
YN1551_RS00845	COG0402	S-adenosylhomocysteine deaminase activity
YN1551_RS00860	COG0028	Belongs to the TPP enzyme family
YN1551_RS00875	COG0644	oxidoreductase
YN1551_RS00885	COG0589	response to stress
YN1551_RS00890	COG0656	L-ascorbic acid biosynthetic process
YN1551_RS00895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
YN1551_RS00920	COG2002	toxin-antitoxin pair type II binding
YN1551_RS00930	COG0586	Pfam SNARE associated Golgi protein
YN1551_RS00935	COG0668	transmembrane transport
YN1551_RS00985	COG1968	undecaprenyl-diphosphatase activity
YN1551_RS01090	COG0437	4 iron, 4 sulfur cluster binding
YN1551_RS01130	COG1063	alcohol dehydrogenase
YN1551_RS01165	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS01205	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
YN1551_RS01255	COG0318	PFAM AMP-dependent synthetase and ligase
YN1551_RS01285	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YN1551_RS01285	COG0674	pyruvate-flavodoxin oxidoreductase activity
YN1551_RS01290	COG1013	pyruvate-flavodoxin oxidoreductase activity
YN1551_RS01300	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
YN1551_RS01305	COG0644	oxidoreductase
YN1551_RS01365	COG3848	Pyruvate phosphate dikinase
YN1551_RS01365	COG0574	Belongs to the PEP-utilizing enzyme family
YN1551_RS01370	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
YN1551_RS01380	COG3383	formate dehydrogenase (NAD+) activity
YN1551_RS01420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YN1551_RS01445	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS01460	COG0395	ABC-type sugar transport system, permease component
YN1551_RS01470	COG0477	Major facilitator Superfamily
YN1551_RS01505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YN1551_RS01510	COG1584	GPR1 FUN34 yaaH family protein
YN1551_RS01535	COG0281	malic enzyme
YN1551_RS01545	COG1250	3-hydroxyacyl-CoA dehydrogenase
YN1551_RS01560	COG0318	PFAM AMP-dependent synthetase and ligase
YN1551_RS01565	COG1960	acyl-CoA dehydrogenase activity
YN1551_RS01575	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
YN1551_RS01575	COG3608	succinylglutamate desuccinylase aspartoacylase
YN1551_RS01595	COG0667	Aldo Keto reductase
YN1551_RS01625	COG2897	thiosulfate sulfurtransferase activity
YN1551_RS01635	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YN1551_RS01760	COG4608	Belongs to the ABC transporter superfamily
YN1551_RS01765	COG0444	Belongs to the ABC transporter superfamily
YN1551_RS01770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YN1551_RS01775	COG0601	transmembrane transport
YN1551_RS01825	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
YN1551_RS01825	COG2857	Cytochrome c1
YN1551_RS01840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YN1551_RS01865	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
YN1551_RS01945	COG1914	H( )-stimulated, divalent metal cation uptake system
YN1551_RS01950	COG1250	3-hydroxyacyl-CoA dehydrogenase
YN1551_RS01955	COG4948	Mandelate Racemase Muconate Lactonizing
YN1551_RS01960	COG0459	protein refolding
YN1551_RS01975	COG1028	Short-chain dehydrogenase reductase Sdr
YN1551_RS01990	COG0673	inositol 2-dehydrogenase activity
YN1551_RS02025	COG1132	(ABC) transporter
YN1551_RS02035	COG0667	Aldo Keto reductase
YN1551_RS02065	COG2723	6-phospho-beta-galactosidase activity
YN1551_RS02075	COG1501	Belongs to the glycosyl hydrolase 31 family
YN1551_RS02100	COG3408	Glycogen debranching enzyme
YN1551_RS02165	COG1472	Belongs to the glycosyl hydrolase 3 family
YN1551_RS02170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YN1551_RS02175	COG3250	beta-galactosidase activity
YN1551_RS02225	COG4608	Belongs to the ABC transporter superfamily
YN1551_RS02230	COG0444	Belongs to the ABC transporter superfamily
YN1551_RS02235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YN1551_RS02245	COG0673	inositol 2-dehydrogenase activity
YN1551_RS02310	COG0318	PFAM AMP-dependent synthetase and ligase
YN1551_RS02325	COG0395	ABC-type sugar transport system, permease component
YN1551_RS02330	COG3842	ATPase activity
YN1551_RS02340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YN1551_RS02390	COG1136	(ABC) transporter
YN1551_RS02410	COG0425	Belongs to the sulfur carrier protein TusA family
YN1551_RS02450	COG1122	ATPase activity
YN1551_RS02495	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YN1551_RS02555	COG2267	carboxylic ester hydrolase activity
YN1551_RS02565	COG0179	Fumarylacetoacetate (FAA) hydrolase
YN1551_RS02570	COG2271	Major facilitator Superfamily
YN1551_RS02575	COG0477	Major facilitator Superfamily
YN1551_RS02585	COG4948	Mandelate Racemase Muconate Lactonizing
YN1551_RS02600	COG2814	Major facilitator Superfamily
YN1551_RS02605	COG1139	Iron-sulfur cluster binding protein
YN1551_RS02615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YN1551_RS02645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YN1551_RS02700	COG1960	acyl-CoA dehydrogenase activity
YN1551_RS02710	COG0477	Major facilitator Superfamily
YN1551_RS02740	COG0655	NAD(P)H dehydrogenase (quinone) activity
YN1551_RS02755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
YN1551_RS02760	COG0095	Lipoate-protein ligase
YN1551_RS02765	COG0247	lactate metabolic process
YN1551_RS02770	COG0277	FAD linked oxidase domain protein
YN1551_RS02805	COG1720	tRNA m6t6A37 methyltransferase activity
YN1551_RS02810	COG0517	IMP dehydrogenase activity
YN1551_RS02810	COG0516	GMP reductase activity
YN1551_RS02820	COG1733	regulation of RNA biosynthetic process
YN1551_RS02920	COG2814	Major facilitator Superfamily
YN1551_RS02935	COG0589	response to stress
YN1551_RS02940	COG0833	amino acid
YN1551_RS02980	COG0243	molybdopterin cofactor binding
YN1551_RS02990	COG1012	belongs to the aldehyde dehydrogenase family
YN1551_RS02995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YN1551_RS03000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YN1551_RS03005	COG4948	Mandelate Racemase Muconate Lactonizing
YN1551_RS03015	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
YN1551_RS03025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YN1551_RS03030	COG1063	alcohol dehydrogenase
YN1551_RS03035	COG0517	IMP dehydrogenase activity
YN1551_RS03035	COG0516	GMP reductase activity
YN1551_RS03040	COG0251	oxidation-reduction process
YN1551_RS03055	COG0656	L-ascorbic acid biosynthetic process
YN1551_RS03065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YN1551_RS03080	COG1444	tRNA N-acetyltransferase activity
YN1551_RS03095	COG0405	Gamma-glutamyltransferase
YN1551_RS03120	COG1830	Aldolase
YN1551_RS03130	COG0517	IMP dehydrogenase activity
YN1551_RS03130	COG0516	GMP reductase activity
YN1551_RS03135	COG0501	Belongs to the peptidase M48B family
YN1551_RS03140	COG0519	Catalyzes the synthesis of GMP from XMP
YN1551_RS03140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
YN1551_RS03160	COG1063	alcohol dehydrogenase
YN1551_RS03180	COG0463	Glycosyl transferase, family 2
YN1551_RS03230	COG1215	transferase activity, transferring glycosyl groups
YN1551_RS03240	COG0351	phosphomethylpyrimidine kinase
YN1551_RS03240	COG0352	thiamine-phosphate diphosphorylase activity
YN1551_RS03245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YN1551_RS03265	COG0123	including yeast histone deacetylase and acetoin utilization protein
YN1551_RS03280	COG2860	membrane
YN1551_RS03305	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
YN1551_RS03315	COG1201	RNA secondary structure unwinding
YN1551_RS03360	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
YN1551_RS03370	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
YN1551_RS03370	COG0617	tRNA 3'-terminal CCA addition
YN1551_RS03370	COG3620	sequence-specific DNA binding
YN1551_RS03390	COG1192	Involved in chromosome partitioning
YN1551_RS03430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YN1551_RS03450	COG0084	hydrolase, TatD family'
YN1551_RS03480	COG1131	(ABC) transporter
YN1551_RS03540	COG1304	FMN binding
YN1551_RS03555	COG1355	regulation of microtubule-based process
YN1551_RS03560	COG0052	Belongs to the universal ribosomal protein uS2 family
YN1551_RS03570	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
YN1551_RS03575	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
YN1551_RS03580	COG0200	Binds to the 23S rRNA
YN1551_RS03590	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
YN1551_RS03595	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YN1551_RS03600	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
YN1551_RS03615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
YN1551_RS03630	COG0456	acetyltransferase
YN1551_RS03630	COG1214	PFAM Peptidase M22, glycoprotease
YN1551_RS03660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
YN1551_RS03675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YN1551_RS03680	COG0561	phosphatase activity
YN1551_RS03685	COG1078	dGTPase activity
YN1551_RS03710	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
YN1551_RS03725	COG2267	carboxylic ester hydrolase activity
YN1551_RS03730	COG1058	Belongs to the CinA family
YN1551_RS03730	COG1546	Belongs to the CinA family
YN1551_RS03735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YN1551_RS03760	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
YN1551_RS03760	COG0617	tRNA 3'-terminal CCA addition
YN1551_RS03760	COG0517	IMP dehydrogenase activity
YN1551_RS03765	COG1201	RNA secondary structure unwinding
YN1551_RS03780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YN1551_RS03835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YN1551_RS03870	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YN1551_RS03915	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YN1551_RS03930	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YN1551_RS03935	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YN1551_RS03950	COG0189	ligase activity
YN1551_RS03955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YN1551_RS03960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YN1551_RS03965	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YN1551_RS04000	COG1122	ATPase activity
YN1551_RS04015	COG0028	Belongs to the TPP enzyme family
YN1551_RS04030	COG0017	Asparaginyl-tRNA synthetase
YN1551_RS04035	COG0585	pseudouridine synthase activity
YN1551_RS04055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YN1551_RS04075	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
YN1551_RS04080	COG0113	porphobilinogen synthase activity
YN1551_RS04085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
YN1551_RS04090	COG0181	hydroxymethylbilane synthase activity
YN1551_RS04115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YN1551_RS04120	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
YN1551_RS04120	COG1793	dna ligase
YN1551_RS04125	COG1793	dna ligase
YN1551_RS04130	COG0717	Belongs to the dCTP deaminase family
YN1551_RS04145	COG2078	PFAM AMMECR1 domain protein
YN1551_RS04175	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
YN1551_RS04190	COG0504	CTP synthase activity
YN1551_RS04195	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
YN1551_RS04215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YN1551_RS04305	COG1489	DNA binding
YN1551_RS04310	COG1401	restriction endodeoxyribonuclease activity
YN1551_RS04425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YN1551_RS04430	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
YN1551_RS04470	COG0051	transcription antitermination factor activity, RNA binding
YN1551_RS04475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YN1551_RS04480	COG0049	tRNA binding
YN1551_RS04505	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YN1551_RS04510	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YN1551_RS04515	COG0085	RNA polymerase activity
YN1551_RS04530	COG0105	UTP biosynthetic process
YN1551_RS04545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
YN1551_RS04550	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
YN1551_RS04565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YN1551_RS04580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YN1551_RS04595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
YN1551_RS04610	COG0077	Prephenate dehydratase
YN1551_RS04610	COG1605	Chorismate mutase
YN1551_RS04635	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
YN1551_RS04635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
YN1551_RS04650	COG1051	belongs to the nudix hydrolase family
YN1551_RS04650	COG1056	cytidyltransferase-related domain
YN1551_RS04685	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
YN1551_RS04725	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YN1551_RS04735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YN1551_RS04770	COG0124	histidyl-tRNA synthetase
YN1551_RS04785	COG0459	protein refolding
YN1551_RS04810	COG1980	fructose-bisphosphate aldolase activity
YN1551_RS04815	COG1121	(ABC) transporter
YN1551_RS04830	COG0477	Major facilitator Superfamily
YN1551_RS04865	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YN1551_RS04885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YN1551_RS04890	COG3959	Transketolase, thiamine diphosphate binding domain
YN1551_RS04895	COG3958	Transketolase
YN1551_RS04900	COG1605	Chorismate mutase
YN1551_RS04900	COG0077	Prephenate dehydratase
YN1551_RS04905	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
YN1551_RS04910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
YN1551_RS04915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YN1551_RS04920	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
YN1551_RS04930	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
YN1551_RS04975	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
YN1551_RS04995	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
YN1551_RS05005	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YN1551_RS05010	COG0649	NAD binding
YN1551_RS05015	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
YN1551_RS05020	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YN1551_RS05030	COG0713	ATP synthesis coupled electron transport
YN1551_RS05035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YN1551_RS05040	COG1007	ATP synthesis coupled electron transport
YN1551_RS05045	COG1260	myo-inositol-1-phosphate synthase
YN1551_RS05050	COG0301	tRNA thio-modification
YN1551_RS05075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YN1551_RS05085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
YN1551_RS05095	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
YN1551_RS05110	COG0552	protein localization to endoplasmic reticulum
YN1551_RS05175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YN1551_RS05190	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YN1551_RS05200	COG0302	gtp cyclohydrolase
YN1551_RS05215	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
YN1551_RS05220	COG3118	belongs to the thioredoxin family
YN1551_RS05225	COG0318	PFAM AMP-dependent synthetase and ligase
YN1551_RS05235	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
YN1551_RS05235	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
YN1551_RS05240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YN1551_RS05245	COG0535	radical SAM domain protein
YN1551_RS05255	COG0475	glutathione-regulated potassium exporter activity
YN1551_RS05275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YN1551_RS05280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YN1551_RS05290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YN1551_RS05295	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
YN1551_RS05340	COG1444	tRNA N-acetyltransferase activity
YN1551_RS05350	COG2813	Specifically methylates the guanine in position
YN1551_RS05355	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YN1551_RS05370	COG1201	RNA secondary structure unwinding
YN1551_RS05390	COG0402	S-adenosylhomocysteine deaminase activity
YN1551_RS05400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
YN1551_RS05420	COG1797	cobyrinic acid a,c-diamide synthase activity
YN1551_RS05435	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
YN1551_RS05465	COG0539	negative regulation of cytoplasmic translation
YN1551_RS05480	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
YN1551_RS05485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YN1551_RS05490	COG1110	DNA topoisomerase II activity
YN1551_RS05535	COG0667	Aldo Keto reductase
YN1551_RS05540	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YN1551_RS05565	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
YN1551_RS05570	COG0163	prenyltransferase activity
YN1551_RS05600	COG0423	glycine-tRNA ligase activity
YN1551_RS05605	COG0010	Belongs to the arginase family
YN1551_RS05640	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YN1551_RS05650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YN1551_RS05680	COG1280	lysine exporter protein (LysE YggA)
YN1551_RS05700	COG0489	protein tyrosine kinase activity
YN1551_RS05730	COG0351	phosphomethylpyrimidine kinase
YN1551_RS05730	COG1992	Thiamine-phosphate synthase
YN1551_RS05750	COG3276	selenocysteine insertion sequence binding
YN1551_RS05760	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
YN1551_RS05765	COG0556	nucleotide-excision repair
YN1551_RS05775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YN1551_RS05800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YN1551_RS05810	COG0805	protein transport
YN1551_RS05820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YN1551_RS05825	COG1121	(ABC) transporter
YN1551_RS05830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
YN1551_RS05845	COG0581	inorganic phosphate transmembrane transporter activity
YN1551_RS05860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YN1551_RS05910	COG0495	leucyl-tRNA aminoacylation
YN1551_RS06015	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
YN1551_RS06040	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
YN1551_RS06045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YN1551_RS06065	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YN1551_RS06070	COG0589	response to stress
YN1551_RS06080	COG0126	phosphoglycerate kinase activity
YN1551_RS06090	COG0668	transmembrane transport
YN1551_RS06105	COG0417	DNA replication proofreading
YN1551_RS06135	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YN1551_RS06155	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
YN1551_RS06165	COG1394	ATPase activity, coupled to movement of substances
YN1551_RS06180	COG0442	prolyl-tRNA aminoacylation
YN1551_RS06190	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
YN1551_RS06195	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
YN1551_RS06210	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
YN1551_RS06220	COG0028	Belongs to the TPP enzyme family
YN1551_RS06230	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
YN1551_RS06255	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
YN1551_RS06265	COG0037	tRNA processing
YN1551_RS06270	COG2096	Adenosyltransferase
YN1551_RS06275	COG0495	leucyl-tRNA aminoacylation
YN1551_RS06285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YN1551_RS06290	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
YN1551_RS06295	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
YN1551_RS06300	COG0131	Imidazoleglycerol-phosphate dehydratase
YN1551_RS06305	COG0107	imidazoleglycerol-phosphate synthase activity
YN1551_RS06310	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YN1551_RS06315	COG0140	phosphoribosyl-ATP diphosphatase activity
YN1551_RS06315	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YN1551_RS06320	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
YN1551_RS06330	COG2151	metal-sulfur cluster biosynthetic enzyme
YN1551_RS06335	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
YN1551_RS06340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YN1551_RS06355	COG1522	sequence-specific DNA binding
YN1551_RS06360	COG2095	MarC family integral membrane protein
YN1551_RS06375	COG0167	dihydroorotate dehydrogenase activity
YN1551_RS06390	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
YN1551_RS06395	COG0540	Belongs to the ATCase OTCase family
YN1551_RS06400	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
YN1551_RS06405	COG0284	orotidine-5'-phosphate decarboxylase activity
YN1551_RS06440	COG0602	queuosine metabolic process
YN1551_RS06445	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YN1551_RS06450	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YN1551_RS06450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YN1551_RS06455	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
YN1551_RS06465	COG0047	phosphoribosylformylglycinamidine synthase activity
YN1551_RS06475	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YN1551_RS06480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YN1551_RS06485	COG0151	Belongs to the GarS family
YN1551_RS06490	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
YN1551_RS06505	COG0137	argininosuccinate synthase activity
YN1551_RS06510	COG0165	Argininosuccinate lyase
YN1551_RS06515	COG0505	Belongs to the CarA family
YN1551_RS06525	COG0189	ligase activity
YN1551_RS06535	COG1250	3-hydroxyacyl-CoA dehydrogenase
YN1551_RS06570	COG1024	Enoyl-CoA hydratase
YN1551_RS06585	COG0460	homoserine dehydrogenase
YN1551_RS06595	COG0864	Transcriptional regulator
YN1551_RS06600	COG0312	modulator of DNA gyrase
YN1551_RS06605	COG0312	modulator of DNA gyrase
YN1551_RS06615	COG0009	L-threonylcarbamoyladenylate synthase
YN1551_RS06620	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YN1551_RS06625	COG2379	hydroxypyruvate reductase
YN1551_RS06635	COG1321	iron dependent repressor
YN1551_RS06670	COG0303	'Molybdopterin
YN1551_RS06685	COG0402	S-adenosylhomocysteine deaminase activity
YN1551_RS06700	COG0067	glutamate synthase
YN1551_RS06705	COG0069	glutamate synthase activity
YN1551_RS06715	COG0577	efflux transmembrane transporter activity
YN1551_RS06725	COG1136	(ABC) transporter
YN1551_RS06815	COG0563	adenylate kinase activity
YN1551_RS06850	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
YN1551_RS06870	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
YN1551_RS06875	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YN1551_RS06885	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
YN1551_RS06895	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
YN1551_RS06900	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YN1551_RS06905	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YN1551_RS06915	COG0255	Belongs to the universal ribosomal protein uL29 family
YN1551_RS06920	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YN1551_RS06925	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
YN1551_RS06930	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YN1551_RS06935	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
YN1551_RS06950	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
YN1551_RS06960	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YN1551_RS06965	COG0473	3-isopropylmalate dehydrogenase activity
YN1551_RS06985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YN1551_RS06990	COG0322	excinuclease ABC activity
YN1551_RS07015	COG1185	polyribonucleotide nucleotidyltransferase activity
YN1551_RS07060	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YN1551_RS07070	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
YN1551_RS07075	COG2264	protein methyltransferase activity
YN1551_RS07080	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
YN1551_RS07115	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
YN1551_RS07130	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
YN1551_RS07145	COG1047	Peptidyl-prolyl cis-trans
YN1551_RS07150	COG0371	Dehydrogenase
YN1551_RS07155	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
YN1551_RS07180	COG1063	alcohol dehydrogenase
YN1551_RS07190	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
YN1551_RS07195	COG1881	PFAM PEBP family protein
YN1551_RS07205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YN1551_RS07210	COG0315	cyclic pyranopterin monophosphate synthase activity
YN1551_RS07270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
YN1551_RS07370	COG0459	protein refolding
YN1551_RS07405	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
YN1551_RS07425	COG0527	aspartate kinase activity
YN1551_RS07425	COG0460	homoserine dehydrogenase
YN1551_RS07430	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
YN1551_RS07450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YN1551_RS07450	COG0574	Belongs to the PEP-utilizing enzyme family
YN1551_RS07455	COG1260	myo-inositol-1-phosphate synthase
YN1551_RS07460	COG1254	Belongs to the acylphosphatase family
YN1551_RS07465	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
YN1551_RS07470	COG0159	tryptophan synthase activity
YN1551_RS07480	COG0135	phosphoribosylanthranilate isomerase activity
YN1551_RS07485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
YN1551_RS07490	COG0512	Glutamine amidotransferase of anthranilate synthase
YN1551_RS07490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YN1551_RS07495	COG0134	indole-3-glycerol-phosphate synthase activity
YN1551_RS07500	COG0436	Aminotransferase
YN1551_RS07505	COG0525	valine-tRNA ligase activity
YN1551_RS07510	COG0644	oxidoreductase
YN1551_RS07545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YN1551_RS07560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YN1551_RS07565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YN1551_RS07585	COG0148	phosphopyruvate hydratase activity
YN1551_RS07605	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YN1551_RS07615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
YN1551_RS07620	COG0509	glycine decarboxylation via glycine cleavage system
YN1551_RS07640	COG0396	ATPase activity
YN1551_RS07645	COG0719	Fe-S assembly protein
YN1551_RS07650	COG0719	Fe-S assembly protein
YN1551_RS07650	COG1372	Participates in initiation and elongation during chromosome replication
YN1551_RS07680	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
YN1551_RS07685	COG0252	asparaginase activity
YN1551_RS07715	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
YN1551_RS07770	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
YN1551_RS07770	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
YN1551_RS07785	COG0154	amidase activity
YN1551_RS07825	COG1110	DNA topoisomerase II activity
YN1551_RS07855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
YN1551_RS07865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
YN1551_RS07870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YN1551_RS07885	COG1028	Short-chain dehydrogenase reductase Sdr
YN1551_RS07895	COG0528	UMP kinase activity
YN1551_RS07905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YN1551_RS07920	COG0469	pyruvate kinase activity
YN1551_RS07940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YN1551_RS07950	COG0297	glycogen (starch) synthase activity
YN1551_RS07990	COG0157	Belongs to the NadC ModD family
YN1551_RS07995	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YN1551_RS08000	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
YN1551_RS08015	COG0395	ABC-type sugar transport system, permease component
YN1551_RS08050	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS08065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YN1551_RS08070	COG0028	Belongs to the TPP enzyme family
YN1551_RS08090	COG2897	thiosulfate sulfurtransferase activity
YN1551_RS08100	COG0651	ATP synthesis coupled electron transport
YN1551_RS08105	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YN1551_RS08110	COG0649	NAD binding
YN1551_RS08115	COG0651	ATP synthesis coupled electron transport
YN1551_RS08125	COG0650	Formate hydrogenlyase subunit 4
YN1551_RS08140	COG3383	formate dehydrogenase (NAD+) activity
YN1551_RS08145	COG0300	oxidoreductase activity
YN1551_RS08150	COG0725	ABC transporter, periplasmic molybdate-binding protein
YN1551_RS08155	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YN1551_RS08200	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YN1551_RS08215	COG1234	tRNA 3'-trailer cleavage
YN1551_RS08260	COG1185	polyribonucleotide nucleotidyltransferase activity
YN1551_RS08280	COG0004	ammonium transporteR
YN1551_RS08320	COG0509	glycine decarboxylation via glycine cleavage system
YN1551_RS08340	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YN1551_RS08345	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YN1551_RS08365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YN1551_RS08365	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YN1551_RS08370	COG0517	IMP dehydrogenase activity
YN1551_RS08380	COG0114	fumarate hydratase activity
YN1551_RS08420	COG1136	(ABC) transporter
YN1551_RS08430	COG1136	(ABC) transporter
YN1551_RS08430	COG0577	efflux transmembrane transporter activity
YN1551_RS08435	COG1846	Transcriptional regulator
YN1551_RS08445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
YN1551_RS08495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YN1551_RS08530	COG2271	Major facilitator Superfamily
YN1551_RS08540	COG0509	glycine decarboxylation via glycine cleavage system
YN1551_RS08570	COG1832	CoA-binding protein
YN1551_RS08585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
YN1551_RS08630	COG2210	Belongs to the sulfur carrier protein TusA family
YN1551_RS08635	COG0425	Belongs to the sulfur carrier protein TusA family
YN1551_RS08665	COG2048	Heterodisulfide reductase, subunit B
YN1551_RS08690	COG0475	glutathione-regulated potassium exporter activity
YN1551_RS08715	COG1131	(ABC) transporter
YN1551_RS08720	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
YN1551_RS08760	COG1960	acyl-CoA dehydrogenase activity
YN1551_RS08795	COG0656	L-ascorbic acid biosynthetic process
YN1551_RS08840	COG2814	Major facilitator Superfamily
YN1551_RS08850	COG3842	ATPase activity
YN1551_RS08855	COG3833	ABC-type maltose transport systems, permease component
YN1551_RS08860	COG1175	transmembrane transport
YN1551_RS08895	COG0436	Aminotransferase
YN1551_RS08905	COG2271	Major facilitator Superfamily
YN1551_RS08980	COG1522	sequence-specific DNA binding
YN1551_RS09040	COG0535	radical SAM domain protein
YN1551_RS09045	COG0535	radical SAM domain protein
YN1551_RS09050	COG1012	belongs to the aldehyde dehydrogenase family
YN1551_RS09090	COG1960	acyl-CoA dehydrogenase activity
YN1551_RS09095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YN1551_RS09105	COG2271	Major facilitator Superfamily
YN1551_RS09110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YN1551_RS09120	COG2368	4-hydroxyphenylacetate
YN1551_RS09150	COG2814	Major facilitator Superfamily
YN1551_RS09165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
YN1551_RS09175	COG1953	Uracil, thiamine, allantoin
YN1551_RS09180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YN1551_RS09190	COG0477	Major facilitator Superfamily
YN1551_RS09250	COG1011	Hydrolase
YN1551_RS09325	COG1024	Enoyl-CoA hydratase
YN1551_RS09335	COG0425	Belongs to the sulfur carrier protein TusA family
YN1551_RS09380	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
YN1551_RS09400	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS09430	COG0045	succinate-CoA ligase (ADP-forming) activity
YN1551_RS09430	COG1042	CoA-binding domain protein
YN1551_RS09430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YN1551_RS09450	COG2226	methyltransferase
YN1551_RS09555	COG2151	metal-sulfur cluster biosynthetic enzyme
YN1551_RS09560	COG0589	response to stress
YN1551_RS09580	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
YN1551_RS09720	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
YN1551_RS09720	COG3608	succinylglutamate desuccinylase aspartoacylase
YN1551_RS09740	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YN1551_RS09835	COG1073	alpha beta
YN1551_RS09845	COG0318	PFAM AMP-dependent synthetase and ligase
YN1551_RS09860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YN1551_RS09875	COG4689	acetoacetate decarboxylase
YN1551_RS09890	COG2271	Major facilitator Superfamily
YN1551_RS09895	COG4948	Mandelate Racemase Muconate Lactonizing
YN1551_RS09900	COG0318	PFAM AMP-dependent synthetase and ligase
YN1551_RS09905	COG2030	dehydratase
YN1551_RS09930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YN1551_RS09940	COG1960	acyl-CoA dehydrogenase activity
YN1551_RS09945	COG0095	Lipoate-protein ligase
YN1551_RS09955	COG1024	Enoyl-CoA hydratase
YN1551_RS09975	COG1250	3-hydroxyacyl-CoA dehydrogenase
YN1551_RS09980	COG0318	PFAM AMP-dependent synthetase and ligase
YN1551_RS09990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YN1551_RS10000	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
YN1551_RS10005	COG0022	dehydrogenase e1 component
YN1551_RS10010	COG3199	ATP-NAD kinase
YN1551_RS10015	COG0508	dehydrogenase complex catalyzes the overall conversion of
YN1551_RS10025	COG1454	alcohol dehydrogenase
YN1551_RS10080	COG2814	Major facilitator Superfamily
YN1551_RS10085	COG1063	alcohol dehydrogenase
YN1551_RS10100	COG1028	Short-chain dehydrogenase reductase Sdr
YN1551_RS10115	COG2271	Major facilitator Superfamily
YN1551_RS10145	COG4948	Mandelate Racemase Muconate Lactonizing
YN1551_RS10155	COG3976	FMN-binding domain protein
YN1551_RS10155	COG1053	succinate dehydrogenase
YN1551_RS10165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YN1551_RS10185	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS10200	COG1012	belongs to the aldehyde dehydrogenase family
YN1551_RS10200	COG2030	dehydratase
YN1551_RS10205	COG1960	acyl-CoA dehydrogenase activity
YN1551_RS10220	COG1063	alcohol dehydrogenase
YN1551_RS10255	COG1012	belongs to the aldehyde dehydrogenase family
YN1551_RS10315	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YN1551_RS10440	COG1337	RAMP superfamily
YN1551_RS10560	COG0393	Putative heavy-metal-binding
YN1551_RS10680	COG0243	molybdopterin cofactor binding
YN1551_RS10725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YN1551_RS10875	COG1953	Uracil, thiamine, allantoin
YN1551_RS10920	COG2814	Major facilitator Superfamily
YN1551_RS10925	COG4948	Mandelate Racemase Muconate Lactonizing
YN1551_RS10970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YN1551_RS10975	COG0477	Major facilitator Superfamily
YN1551_RS10985	COG1028	Short-chain dehydrogenase reductase Sdr
YN1551_RS11100	COG1091	dTDP-4-dehydrorhamnose reductase activity
YN1551_RS11105	COG3511	phospholipase C
YN1551_RS11130	COG0438	transferase activity, transferring glycosyl groups
YN1551_RS11145	COG1215	transferase activity, transferring glycosyl groups
YN1551_RS11150	COG0438	transferase activity, transferring glycosyl groups
YN1551_RS11180	COG1215	transferase activity, transferring glycosyl groups
YN1551_RS11185	COG0438	transferase activity, transferring glycosyl groups
YN1551_RS11190	COG0438	transferase activity, transferring glycosyl groups
YN1551_RS11200	COG0438	transferase activity, transferring glycosyl groups
YN1551_RS11245	COG1216	Glycosyl transferase, family 2
YN1551_RS11285	COG0463	Glycosyl transferase, family 2
YN1551_RS11290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YN1551_RS11295	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
YN1551_RS11315	COG0463	Glycosyl transferase, family 2
YN1551_RS11345	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS11380	COG2224	Isocitrate lyase
YN1551_RS11385	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YN1551_RS11405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YN1551_RS11410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YN1551_RS11415	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
YN1551_RS11415	COG2146	nitrite reductase [NAD(P)H] activity
YN1551_RS11450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YN1551_RS11455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YN1551_RS11460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YN1551_RS11555	COG1215	transferase activity, transferring glycosyl groups
YN1551_RS11565	COG2264	protein methyltransferase activity
YN1551_RS11590	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS11620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YN1551_RS11625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
YN1551_RS11650	COG1216	Glycosyl transferase, family 2
YN1551_RS11925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
YN1551_RS11945	COG1131	(ABC) transporter
YN1551_RS11975	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS11995	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
YN1551_RS12025	COG1473	amidohydrolase
YN1551_RS12085	COG1725	Transcriptional regulator
YN1551_RS12115	COG0318	PFAM AMP-dependent synthetase and ligase
YN1551_RS12120	COG1960	acyl-CoA dehydrogenase activity
YN1551_RS12140	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YN1551_RS12165	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
YN1551_RS12240	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YN1551_RS12250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YN1551_RS12250	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
YN1551_RS12280	COG4608	Belongs to the ABC transporter superfamily
YN1551_RS12285	COG0444	Belongs to the ABC transporter superfamily
YN1551_RS12295	COG0601	transmembrane transport
YN1551_RS12310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YN1551_RS12325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YN1551_RS12330	COG1131	(ABC) transporter
YN1551_RS12355	COG2721	sulfolactate sulfo-lyase activity
YN1551_RS12360	COG2721	sulfolactate sulfo-lyase activity
YN1551_RS12375	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YN1551_RS12390	COG1802	Transcriptional regulator
YN1551_RS12395	COG2301	Belongs to the HpcH HpaI aldolase family
YN1551_RS12400	COG2050	protein possibly involved in aromatic compounds catabolism
YN1551_RS12400	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
YN1551_RS12415	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS12455	COG2084	Dehydrogenase
YN1551_RS12520	COG0412	Dienelactone hydrolase
YN1551_RS12560	COG4946	Tricorn protease homolog
YN1551_RS12560	COG0793	Belongs to the peptidase S41A family
YN1551_RS12565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YN1551_RS12595	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YN1551_RS12630	COG1012	belongs to the aldehyde dehydrogenase family
YN1551_RS12655	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
YN1551_RS12665	COG1024	Enoyl-CoA hydratase
YN1551_RS12700	COG0028	Belongs to the TPP enzyme family
YN1551_RS12705	COG2151	metal-sulfur cluster biosynthetic enzyme
YN1551_RS12740	COG3350	monooxygenase activity
YN1551_RS12785	COG1012	belongs to the aldehyde dehydrogenase family
YN1551_RS12810	COG0277	FAD linked oxidase domain protein
YN1551_RS12865	COG0674	pyruvate-flavodoxin oxidoreductase activity
YN1551_RS12875	COG2062	phosphohistidine phosphatase, SixA
YN1551_RS12885	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
YN1551_RS12890	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
YN1551_RS12910	COG3573	Dehydrogenase
YN1551_RS12955	COG0450	alkyl hydroperoxide reductase
YN1551_RS12980	COG1620	l-lactate permease
YN1551_RS12995	COG0674	pyruvate-flavodoxin oxidoreductase activity
YN1551_RS13000	COG1013	pyruvate-flavodoxin oxidoreductase activity
YN1551_RS13005	COG1522	sequence-specific DNA binding
YN1551_RS13015	COG1305	Transglutaminase-like
YN1551_RS13020	COG0432	Pfam Uncharacterised protein family UPF0047
YN1551_RS13085	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS13135	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
YN1551_RS13140	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YN1551_RS13155	COG0189	ligase activity
YN1551_RS13195	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
YN1551_RS13215	COG1053	succinate dehydrogenase
YN1551_RS13235	COG2304	oxidoreductase activity
YN1551_RS13240	COG0714	Associated with various cellular activities
YN1551_RS13265	COG0083	homoserine kinase activity
YN1551_RS13270	COG0626	cystathionine gamma-synthase activity
YN1551_RS13310	COG0183	Belongs to the thiolase family
YN1551_RS13315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YN1551_RS13355	COG1215	transferase activity, transferring glycosyl groups
YN1551_RS13360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YN1551_RS13370	COG0351	phosphomethylpyrimidine kinase
YN1551_RS13375	COG0314	molybdopterin synthase activity
YN1551_RS13400	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
YN1551_RS13410	COG1131	(ABC) transporter
YN1551_RS13415	COG1668	transmembrane transport
YN1551_RS13445	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
YN1551_RS13450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YN1551_RS13480	COG0720	synthase
YN1551_RS13505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YN1551_RS13525	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YN1551_RS13525	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YN1551_RS13535	COG0071	Belongs to the small heat shock protein (HSP20) family
YN1551_RS13595	COG0402	S-adenosylhomocysteine deaminase activity
YN1551_RS13620	COG0430	RNA-3'-phosphate cyclase activity
YN1551_RS13630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
YN1551_RS13635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YN1551_RS13650	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
YN1551_RS13655	COG5599	Phosphatase
YN1551_RS13660	COG1515	deoxyribonuclease V activity
YN1551_RS13665	COG1335	isochorismatase
YN1551_RS13700	COG4581	dead DEAH box helicase
YN1551_RS13710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YN1551_RS13720	COG0439	Biotin carboxylase
YN1551_RS13730	COG1116	anion transmembrane transporter activity
YN1551_RS13740	COG0066	3-isopropylmalate dehydratase activity
YN1551_RS13745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YN1551_RS13750	COG0415	Belongs to the DNA photolyase family
YN1551_RS13785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YN1551_RS13830	COG0045	succinate-CoA ligase (ADP-forming) activity
YN1551_RS13845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YN1551_RS13850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YN1551_RS13880	COG0657	acetylesterase activity
YN1551_RS13885	COG1063	alcohol dehydrogenase
YN1551_RS13890	COG0183	Belongs to the thiolase family
YN1551_RS13895	COG1960	acyl-CoA dehydrogenase activity
YN1551_RS13900	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YN1551_RS13905	COG1028	Short-chain dehydrogenase reductase Sdr
YN1551_RS13910	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
YN1551_RS13950	COG0318	PFAM AMP-dependent synthetase and ligase
YN1551_RS13955	COG1960	acyl-CoA dehydrogenase activity
YN1551_RS13960	COG1250	3-hydroxyacyl-CoA dehydrogenase
YN1551_RS13965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YN1551_RS13970	COG2814	Major facilitator Superfamily
YN1551_RS13970	COG0477	Major facilitator Superfamily
YN1551_RS14005	COG0318	PFAM AMP-dependent synthetase and ligase
YN1551_RS14015	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YN1551_RS14020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YN1551_RS14035	COG1131	(ABC) transporter
YN1551_RS14095	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
YN1551_RS14105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YN1551_RS14125	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS14135	COG2217	Heavy metal translocating P-type atpase
YN1551_RS14170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YN1551_RS14185	COG1063	alcohol dehydrogenase
YN1551_RS14195	COG0395	ABC-type sugar transport system, permease component
YN1551_RS14230	COG0813	purine-nucleoside phosphorylase activity
YN1551_RS14235	COG3386	PFAM SMP-30 Gluconolaconase
YN1551_RS14240	COG2814	Major facilitator Superfamily
YN1551_RS14270	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
YN1551_RS14290	COG4274	PFAM GYD family protein
YN1551_RS14300	COG4946	Tricorn protease homolog
YN1551_RS14300	COG1506	peptidase
YN1551_RS14300	COG0823	Involved in the tonB-independent uptake of proteins
YN1551_RS14315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YN1551_RS14400	COG4608	Belongs to the ABC transporter superfamily
YN1551_RS14405	COG0444	Belongs to the ABC transporter superfamily
YN1551_RS14420	COG0601	transmembrane transport
YN1551_RS14435	COG4948	Mandelate Racemase Muconate Lactonizing
YN1551_RS14440	COG1028	Short-chain dehydrogenase reductase Sdr
YN1551_RS14495	COG2217	Heavy metal translocating P-type atpase
YN1551_RS14505	COG4555	ABC transporter
YN1551_RS14535	COG1592	Rubrerythrin
YN1551_RS14570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YN1551_RS14620	COG0183	Belongs to the thiolase family
YN1551_RS14630	COG1024	Enoyl-CoA hydratase
YN1551_RS14665	COG0601	transmembrane transport
YN1551_RS14670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YN1551_RS14675	COG0444	Belongs to the ABC transporter superfamily
YN1551_RS14680	COG4608	Belongs to the ABC transporter superfamily
YN1551_RS14690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YN1551_RS14695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YN1551_RS14710	COG0438	transferase activity, transferring glycosyl groups
YN1551_RS14730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YN1551_RS14755	COG1131	(ABC) transporter
YN1551_RS14760	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
YN1551_RS14765	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS14775	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
YN1551_RS14780	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YN1551_RS14800	COG0149	triose-phosphate isomerase activity
YN1551_RS14815	COG0372	Belongs to the citrate synthase family
YN1551_RS14820	COG0516	GMP reductase activity
YN1551_RS14820	COG0517	IMP dehydrogenase activity
YN1551_RS14825	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
YN1551_RS14830	COG2079	MmgE PrpD family protein
YN1551_RS14835	COG0039	L-malate dehydrogenase activity
YN1551_RS14840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YN1551_RS14870	COG0750	zinc metalloprotease
YN1551_RS14890	COG1489	DNA binding
YN1551_RS14920	COG0778	Nitroreductase
YN1551_RS14925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YN1551_RS15000	COG3547	Transposase (IS116 IS110 IS902 family)
YN1551_RS15085	COG0561	phosphatase activity
YN1551_RS15095	COG1011	Hydrolase
YN1551_RS15110	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YN1551_RS15145	COG0494	nUDIX hydrolase
YN1551_RS15155	COG3253	May function as heme-dependent peroxidase
YN1551_RS15170	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YN1551_RS15200	COG2226	methyltransferase
YN1551_RS15225	COG0538	isocitrate dehydrogenase activity
YN1551_RS15355	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
YN1551_RS15435	COG1192	Involved in chromosome partitioning
YN1551_RS15515	COG1063	alcohol dehydrogenase
YN1551_RS15525	COG0515	serine threonine protein kinase
YN1551_RS15525	COG2815	serine threonine protein kinase
YN1551_RS15855	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YN1551_RS16015	COG4948	Mandelate Racemase Muconate Lactonizing
YN1551_RS16085	COG1305	Transglutaminase-like
YN1551_RS16335	COG0626	cystathionine gamma-synthase activity