locus-tag	class	description
SSOL_RS00005	COG0538	isocitrate dehydrogenase activity
SSOL_RS00030	COG2154	pterin-4-alpha-carbinolamine dehydratase
SSOL_RS00110	COG1331	Highly conserved protein containing a thioredoxin domain
SSOL_RS00115	COG1028	Short-chain dehydrogenase reductase Sdr
SSOL_RS00120	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SSOL_RS00130	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SSOL_RS00155	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SSOL_RS00170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SSOL_RS00195	COG0492	ferredoxin-NADP+ reductase activity
SSOL_RS00240	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
SSOL_RS00265	COG0588	phosphoglycerate mutase activity
SSOL_RS00295	COG1957	nucleoside hydrolase
SSOL_RS00325	COG0497	DNA recombination
SSOL_RS00345	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SSOL_RS00345	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SSOL_RS00350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SSOL_RS00355	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
SSOL_RS00390	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SSOL_RS00435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SSOL_RS00440	COG1573	uracil-dna glycosylase
SSOL_RS00445	COG1028	Short-chain dehydrogenase reductase Sdr
SSOL_RS00470	COG0215	cysteine-tRNA ligase activity
SSOL_RS00475	COG2222	sugar isomerase
SSOL_RS00485	COG0446	pyridine nucleotide-disulphide oxidoreductase
SSOL_RS00495	COG0433	COG0433 Predicted ATPase
SSOL_RS00505	COG1607	acyl-coa hydrolase
SSOL_RS00520	COG0708	Exodeoxyribonuclease III
SSOL_RS00525	COG0515	serine threonine protein kinase
SSOL_RS00525	COG2815	serine threonine protein kinase
SSOL_RS00590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SSOL_RS00735	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SSOL_RS00740	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SSOL_RS00755	COG0189	ligase activity
SSOL_RS00795	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SSOL_RS00815	COG1053	succinate dehydrogenase
SSOL_RS00835	COG2304	oxidoreductase activity
SSOL_RS00840	COG0714	Associated with various cellular activities
SSOL_RS00860	COG0083	homoserine kinase activity
SSOL_RS00865	COG0626	cystathionine gamma-synthase activity
SSOL_RS00905	COG0183	Belongs to the thiolase family
SSOL_RS00910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SSOL_RS00955	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SSOL_RS00965	COG0351	phosphomethylpyrimidine kinase
SSOL_RS00970	COG0314	molybdopterin synthase activity
SSOL_RS01005	COG1131	(ABC) transporter
SSOL_RS01010	COG1668	transmembrane transport
SSOL_RS01030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SSOL_RS01035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SSOL_RS01065	COG0720	synthase
SSOL_RS01080	COG0492	ferredoxin-NADP+ reductase activity
SSOL_RS01085	COG0483	inositol monophosphate 1-phosphatase activity
SSOL_RS01090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SSOL_RS01105	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SSOL_RS01110	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SSOL_RS01110	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SSOL_RS01120	COG0071	Belongs to the small heat shock protein (HSP20) family
SSOL_RS01180	COG0402	S-adenosylhomocysteine deaminase activity
SSOL_RS01205	COG0430	RNA-3'-phosphate cyclase activity
SSOL_RS01220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SSOL_RS01225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SSOL_RS01235	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SSOL_RS01245	COG1515	deoxyribonuclease V activity
SSOL_RS01290	COG4581	dead DEAH box helicase
SSOL_RS01295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SSOL_RS01305	COG0439	Biotin carboxylase
SSOL_RS01315	COG1116	anion transmembrane transporter activity
SSOL_RS01320	COG0066	3-isopropylmalate dehydratase activity
SSOL_RS01325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SSOL_RS01330	COG0415	Belongs to the DNA photolyase family
SSOL_RS01385	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SSOL_RS01405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SSOL_RS01410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SSOL_RS01425	COG0045	succinate-CoA ligase (ADP-forming) activity
SSOL_RS01495	COG1063	alcohol dehydrogenase
SSOL_RS01500	COG0183	Belongs to the thiolase family
SSOL_RS01505	COG1960	acyl-CoA dehydrogenase activity
SSOL_RS01510	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SSOL_RS01515	COG1028	Short-chain dehydrogenase reductase Sdr
SSOL_RS01520	COG1064	alcohol dehydrogenase
SSOL_RS01540	COG1309	transcriptional regulator
SSOL_RS01565	COG0318	PFAM AMP-dependent synthetase and ligase
SSOL_RS01570	COG1960	acyl-CoA dehydrogenase activity
SSOL_RS01575	COG1024	Enoyl-CoA hydratase
SSOL_RS01580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SSOL_RS01585	COG0477	Major facilitator Superfamily
SSOL_RS01610	COG0657	acetylesterase activity
SSOL_RS01620	COG0318	PFAM AMP-dependent synthetase and ligase
SSOL_RS01630	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SSOL_RS01635	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SSOL_RS01640	COG0477	Major facilitator Superfamily
SSOL_RS01660	COG0432	Pfam Uncharacterised protein family UPF0047
SSOL_RS01670	COG1024	Enoyl-CoA hydratase
SSOL_RS01680	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SSOL_RS01820	COG0477	Major facilitator Superfamily
SSOL_RS01825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SSOL_RS01830	COG0778	Nitroreductase
SSOL_RS01885	COG1489	DNA binding
SSOL_RS01905	COG0750	zinc metalloprotease
SSOL_RS01940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SSOL_RS01945	COG0039	L-malate dehydrogenase activity
SSOL_RS01950	COG2079	MmgE PrpD family protein
SSOL_RS01955	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SSOL_RS01960	COG0516	GMP reductase activity
SSOL_RS01960	COG0517	IMP dehydrogenase activity
SSOL_RS01965	COG0372	Belongs to the citrate synthase family
SSOL_RS01980	COG0149	triose-phosphate isomerase activity
SSOL_RS02010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SSOL_RS02015	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SSOL_RS02045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SSOL_RS02065	COG0438	transferase activity, transferring glycosyl groups
SSOL_RS02080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SSOL_RS02085	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SSOL_RS02095	COG4608	Belongs to the ABC transporter superfamily
SSOL_RS02100	COG0444	Belongs to the ABC transporter superfamily
SSOL_RS02105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SSOL_RS02110	COG0601	transmembrane transport
SSOL_RS02145	COG0183	Belongs to the thiolase family
SSOL_RS02230	COG1592	Rubrerythrin
SSOL_RS02255	COG4555	ABC transporter
SSOL_RS02265	COG2217	Heavy metal translocating P-type atpase
SSOL_RS02325	COG1028	Short-chain dehydrogenase reductase Sdr
SSOL_RS02330	COG4948	Mandelate Racemase Muconate Lactonizing
SSOL_RS02370	COG0444	Belongs to the ABC transporter superfamily
SSOL_RS02375	COG4608	Belongs to the ABC transporter superfamily
SSOL_RS02380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SSOL_RS02425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SSOL_RS02465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SSOL_RS02475	COG2239	Acts as a magnesium transporter
SSOL_RS02480	COG0823	Involved in the tonB-independent uptake of proteins
SSOL_RS02480	COG1506	peptidase
SSOL_RS02480	COG4946	Tricorn protease homolog
SSOL_RS02485	COG0501	Belongs to the peptidase M48B family
SSOL_RS02490	COG4274	PFAM GYD family protein
SSOL_RS02535	COG2814	Major facilitator Superfamily
SSOL_RS02540	COG3386	PFAM SMP-30 Gluconolaconase
SSOL_RS02545	COG0813	purine-nucleoside phosphorylase activity
SSOL_RS02580	COG0395	ABC-type sugar transport system, permease component
SSOL_RS02585	COG2814	Major facilitator Superfamily
SSOL_RS02590	COG1063	alcohol dehydrogenase
SSOL_RS02600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SSOL_RS02675	COG1573	uracil-dna glycosylase
SSOL_RS02700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SSOL_RS02710	COG0517	IMP dehydrogenase activity
SSOL_RS02720	COG3387	PFAM Glycoside hydrolase 15-related
SSOL_RS02780	COG3387	PFAM Glycoside hydrolase 15-related
SSOL_RS02785	COG0438	transferase activity, transferring glycosyl groups
SSOL_RS02790	COG1013	pyruvate-flavodoxin oxidoreductase activity
SSOL_RS02795	COG0674	pyruvate-flavodoxin oxidoreductase activity
SSOL_RS02800	COG1144	Oxidoreductase
SSOL_RS02805	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SSOL_RS02810	COG0437	4 iron, 4 sulfur cluster binding
SSOL_RS02825	COG1960	acyl-CoA dehydrogenase activity
SSOL_RS02835	COG2086	electron transfer activity
SSOL_RS02845	COG0492	ferredoxin-NADP+ reductase activity
SSOL_RS02865	COG0668	transmembrane transport
SSOL_RS02870	COG0402	S-adenosylhomocysteine deaminase activity
SSOL_RS02885	COG3962	Belongs to the TPP enzyme family
SSOL_RS02890	COG0438	transferase activity, transferring glycosyl groups
SSOL_RS02900	COG0644	oxidoreductase
SSOL_RS02910	COG0589	response to stress
SSOL_RS02915	COG0656	L-ascorbic acid biosynthetic process
SSOL_RS02965	COG0668	transmembrane transport
SSOL_RS02970	COG0586	Pfam SNARE associated Golgi protein
SSOL_RS02980	COG3511	phospholipase C
SSOL_RS03005	COG0437	4 iron, 4 sulfur cluster binding
SSOL_RS03010	COG0243	molybdopterin cofactor binding
SSOL_RS03035	COG1063	alcohol dehydrogenase
SSOL_RS03055	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SSOL_RS03080	COG0318	PFAM AMP-dependent synthetase and ligase
SSOL_RS03115	COG0674	pyruvate-flavodoxin oxidoreductase activity
SSOL_RS03115	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SSOL_RS03120	COG1013	pyruvate-flavodoxin oxidoreductase activity
SSOL_RS03125	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SSOL_RS03130	COG0644	oxidoreductase
SSOL_RS03140	COG3848	Pyruvate phosphate dikinase
SSOL_RS03140	COG0574	Belongs to the PEP-utilizing enzyme family
SSOL_RS03145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SSOL_RS03155	COG3383	formate dehydrogenase (NAD+) activity
SSOL_RS03195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SSOL_RS03245	COG0395	ABC-type sugar transport system, permease component
SSOL_RS03250	COG3842	ATPase activity
SSOL_RS03255	COG0477	Major facilitator Superfamily
SSOL_RS03290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SSOL_RS03295	COG1584	GPR1 FUN34 yaaH family protein
SSOL_RS03320	COG0281	malic enzyme
SSOL_RS03330	COG1250	3-hydroxyacyl-CoA dehydrogenase
SSOL_RS03345	COG0318	PFAM AMP-dependent synthetase and ligase
SSOL_RS03350	COG1960	acyl-CoA dehydrogenase activity
SSOL_RS03360	COG3608	succinylglutamate desuccinylase aspartoacylase
SSOL_RS03360	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SSOL_RS03415	COG2217	Heavy metal translocating P-type atpase
SSOL_RS03440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SSOL_RS03440	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SSOL_RS03450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SSOL_RS03490	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SSOL_RS03610	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
SSOL_RS03625	COG0477	Major facilitator Superfamily
SSOL_RS03630	COG3473	Maleate cis-trans isomerase
SSOL_RS03640	COG0179	Fumarylacetoacetate (FAA) hydrolase
SSOL_RS03710	COG4608	Belongs to the ABC transporter superfamily
SSOL_RS03715	COG0444	Belongs to the ABC transporter superfamily
SSOL_RS03720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SSOL_RS03725	COG0601	transmembrane transport
SSOL_RS03775	COG2857	Cytochrome c1
SSOL_RS03775	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SSOL_RS03790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SSOL_RS03810	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SSOL_RS03890	COG1914	H( )-stimulated, divalent metal cation uptake system
SSOL_RS03895	COG1250	3-hydroxyacyl-CoA dehydrogenase
SSOL_RS03900	COG4948	Mandelate Racemase Muconate Lactonizing
SSOL_RS03905	COG0459	protein refolding
SSOL_RS03940	COG0667	Aldo Keto reductase
SSOL_RS03990	COG0318	PFAM AMP-dependent synthetase and ligase
SSOL_RS04005	COG0395	ABC-type sugar transport system, permease component
SSOL_RS04010	COG3842	ATPase activity
SSOL_RS04020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SSOL_RS04090	COG1136	(ABC) transporter
SSOL_RS04110	COG0425	Belongs to the sulfur carrier protein TusA family
SSOL_RS04150	COG1122	ATPase activity
SSOL_RS04195	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SSOL_RS04210	COG0805	protein transport
SSOL_RS04240	COG1028	Short-chain dehydrogenase reductase Sdr
SSOL_RS04250	COG2267	carboxylic ester hydrolase activity
SSOL_RS04260	COG0179	Fumarylacetoacetate (FAA) hydrolase
SSOL_RS04265	COG2271	Major facilitator Superfamily
SSOL_RS04280	COG4948	Mandelate Racemase Muconate Lactonizing
SSOL_RS04305	COG2814	Major facilitator Superfamily
SSOL_RS04310	COG1139	Iron-sulfur cluster binding protein
SSOL_RS04320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SSOL_RS04335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SSOL_RS04365	COG2271	Major facilitator Superfamily
SSOL_RS04395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SSOL_RS04430	COG0655	NAD(P)H dehydrogenase (quinone) activity
SSOL_RS04445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SSOL_RS04450	COG0095	Lipoate-protein ligase
SSOL_RS04455	COG0247	lactate metabolic process
SSOL_RS04460	COG0277	FAD linked oxidase domain protein
SSOL_RS04500	COG1720	tRNA m6t6A37 methyltransferase activity
SSOL_RS04515	COG0517	IMP dehydrogenase activity
SSOL_RS04515	COG0516	GMP reductase activity
SSOL_RS04525	COG1733	regulation of RNA biosynthetic process
SSOL_RS04545	COG2814	Major facilitator Superfamily
SSOL_RS04555	COG0515	serine threonine protein kinase
SSOL_RS04555	COG2815	serine threonine protein kinase
SSOL_RS04560	COG0589	response to stress
SSOL_RS04565	COG0833	amino acid
SSOL_RS04595	COG0243	molybdopterin cofactor binding
SSOL_RS04600	COG0530	calcium, potassium:sodium antiporter activity
SSOL_RS04605	COG1012	belongs to the aldehyde dehydrogenase family
SSOL_RS04615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SSOL_RS04620	COG4948	Mandelate Racemase Muconate Lactonizing
SSOL_RS04635	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SSOL_RS04645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SSOL_RS04650	COG1063	alcohol dehydrogenase
SSOL_RS04655	COG0517	IMP dehydrogenase activity
SSOL_RS04655	COG0516	GMP reductase activity
SSOL_RS04675	COG0656	L-ascorbic acid biosynthetic process
SSOL_RS04690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SSOL_RS04705	COG1444	tRNA N-acetyltransferase activity
SSOL_RS04720	COG0405	Gamma-glutamyltransferase
SSOL_RS04755	COG1830	Aldolase
SSOL_RS04765	COG0517	IMP dehydrogenase activity
SSOL_RS04765	COG0516	GMP reductase activity
SSOL_RS04770	COG0501	Belongs to the peptidase M48B family
SSOL_RS04775	COG0519	Catalyzes the synthesis of GMP from XMP
SSOL_RS04775	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SSOL_RS04785	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SSOL_RS04795	COG1063	alcohol dehydrogenase
SSOL_RS04815	COG0463	Glycosyl transferase, family 2
SSOL_RS04865	COG1215	transferase activity, transferring glycosyl groups
SSOL_RS04875	COG0351	phosphomethylpyrimidine kinase
SSOL_RS04875	COG0352	thiamine-phosphate diphosphorylase activity
SSOL_RS04880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SSOL_RS04900	COG0123	including yeast histone deacetylase and acetoin utilization protein
SSOL_RS04915	COG2860	membrane
SSOL_RS04940	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SSOL_RS04950	COG1201	RNA secondary structure unwinding
SSOL_RS04995	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SSOL_RS05005	COG3620	sequence-specific DNA binding
SSOL_RS05005	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SSOL_RS05005	COG0617	tRNA 3'-terminal CCA addition
SSOL_RS05025	COG1192	Involved in chromosome partitioning
SSOL_RS05120	COG1131	(ABC) transporter
SSOL_RS05175	COG1304	FMN binding
SSOL_RS05190	COG1355	regulation of microtubule-based process
SSOL_RS05195	COG0052	Belongs to the universal ribosomal protein uS2 family
SSOL_RS05205	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SSOL_RS05210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SSOL_RS05215	COG0200	Binds to the 23S rRNA
SSOL_RS05225	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SSOL_RS05230	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SSOL_RS05235	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SSOL_RS05250	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SSOL_RS05265	COG0456	acetyltransferase
SSOL_RS05265	COG1214	PFAM Peptidase M22, glycoprotease
SSOL_RS05290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SSOL_RS05295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SSOL_RS05310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SSOL_RS05315	COG0561	phosphatase activity
SSOL_RS05320	COG1078	dGTPase activity
SSOL_RS05345	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SSOL_RS05360	COG2267	carboxylic ester hydrolase activity
SSOL_RS05365	COG1546	Belongs to the CinA family
SSOL_RS05365	COG1058	Belongs to the CinA family
SSOL_RS05370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SSOL_RS05395	COG0517	IMP dehydrogenase activity
SSOL_RS05395	COG0617	tRNA 3'-terminal CCA addition
SSOL_RS05395	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SSOL_RS05400	COG1201	RNA secondary structure unwinding
SSOL_RS05415	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SSOL_RS05470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SSOL_RS05575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SSOL_RS05620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SSOL_RS05625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SSOL_RS05640	COG0189	ligase activity
SSOL_RS05645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SSOL_RS05650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SSOL_RS05655	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SSOL_RS05680	COG1129	ABC transporter
SSOL_RS05695	COG0028	Belongs to the TPP enzyme family
SSOL_RS05710	COG0017	Asparaginyl-tRNA synthetase
SSOL_RS05715	COG0585	pseudouridine synthase activity
SSOL_RS05735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SSOL_RS05750	COG1648	precorrin-2 dehydrogenase activity
SSOL_RS05750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SSOL_RS05755	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SSOL_RS05760	COG0113	porphobilinogen synthase activity
SSOL_RS05765	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SSOL_RS05770	COG0181	hydroxymethylbilane synthase activity
SSOL_RS05795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SSOL_RS05805	COG1793	dna ligase
SSOL_RS05810	COG0717	Belongs to the dCTP deaminase family
SSOL_RS05855	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
SSOL_RS05870	COG0504	CTP synthase activity
SSOL_RS05875	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SSOL_RS05895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SSOL_RS05905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SSOL_RS05910	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SSOL_RS05950	COG0051	transcription antitermination factor activity, RNA binding
SSOL_RS05955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SSOL_RS05960	COG0049	tRNA binding
SSOL_RS05985	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SSOL_RS05990	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SSOL_RS05995	COG0085	RNA polymerase activity
SSOL_RS06025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SSOL_RS06030	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SSOL_RS06045	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SSOL_RS06060	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SSOL_RS06075	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SSOL_RS06090	COG1605	Chorismate mutase
SSOL_RS06090	COG0077	Prephenate dehydratase
SSOL_RS06115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SSOL_RS06115	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SSOL_RS06130	COG1051	belongs to the nudix hydrolase family
SSOL_RS06130	COG1056	cytidyltransferase-related domain
SSOL_RS06165	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SSOL_RS06205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SSOL_RS06215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SSOL_RS06230	COG0343	queuine tRNA-ribosyltransferase activity
SSOL_RS06250	COG0124	histidyl-tRNA synthetase
SSOL_RS06265	COG0459	protein refolding
SSOL_RS06290	COG1980	fructose-bisphosphate aldolase activity
SSOL_RS06295	COG1121	(ABC) transporter
SSOL_RS06305	COG0477	Major facilitator Superfamily
SSOL_RS06330	COG1185	polyribonucleotide nucleotidyltransferase activity
SSOL_RS06340	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SSOL_RS06360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SSOL_RS06365	COG3959	Transketolase, thiamine diphosphate binding domain
SSOL_RS06370	COG3958	Transketolase
SSOL_RS06375	COG1605	Chorismate mutase
SSOL_RS06375	COG0077	Prephenate dehydratase
SSOL_RS06380	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SSOL_RS06385	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SSOL_RS06390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SSOL_RS06395	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SSOL_RS06405	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SSOL_RS06425	COG1199	ATP-dependent helicase activity
SSOL_RS06445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SSOL_RS06450	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SSOL_RS06480	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SSOL_RS06485	COG0649	NAD binding
SSOL_RS06490	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SSOL_RS06495	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SSOL_RS06505	COG0713	ATP synthesis coupled electron transport
SSOL_RS06510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SSOL_RS06515	COG1007	ATP synthesis coupled electron transport
SSOL_RS06520	COG1260	myo-inositol-1-phosphate synthase
SSOL_RS06525	COG0301	tRNA thio-modification
SSOL_RS06555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SSOL_RS06565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SSOL_RS06575	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SSOL_RS06590	COG0552	protein localization to endoplasmic reticulum
SSOL_RS06655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SSOL_RS06670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SSOL_RS06680	COG0302	gtp cyclohydrolase
SSOL_RS06700	COG3118	belongs to the thioredoxin family
SSOL_RS06705	COG0318	PFAM AMP-dependent synthetase and ligase
SSOL_RS06720	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SSOL_RS06725	COG0535	radical SAM domain protein
SSOL_RS06735	COG0475	glutathione-regulated potassium exporter activity
SSOL_RS06765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SSOL_RS06780	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SSOL_RS06785	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SSOL_RS06805	COG0438	transferase activity, transferring glycosyl groups
SSOL_RS06830	COG1444	tRNA N-acetyltransferase activity
SSOL_RS06840	COG2813	Specifically methylates the guanine in position
SSOL_RS06845	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SSOL_RS06850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SSOL_RS06860	COG1201	RNA secondary structure unwinding
SSOL_RS06880	COG0402	S-adenosylhomocysteine deaminase activity
SSOL_RS06890	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SSOL_RS06910	COG1797	cobyrinic acid a,c-diamide synthase activity
SSOL_RS06925	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SSOL_RS06955	COG0539	negative regulation of cytoplasmic translation
SSOL_RS06970	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
SSOL_RS06975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SSOL_RS06980	COG1110	DNA topoisomerase II activity
SSOL_RS07005	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SSOL_RS07025	COG0667	Aldo Keto reductase
SSOL_RS07030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SSOL_RS07040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SSOL_RS07050	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
SSOL_RS07055	COG0163	prenyltransferase activity
SSOL_RS07085	COG0423	glycine-tRNA ligase activity
SSOL_RS07090	COG0010	Belongs to the arginase family
SSOL_RS07125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SSOL_RS07135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SSOL_RS07165	COG1280	lysine exporter protein (LysE YggA)
SSOL_RS07185	COG0489	protein tyrosine kinase activity
SSOL_RS07225	COG0351	phosphomethylpyrimidine kinase
SSOL_RS07225	COG1992	Thiamine-phosphate synthase
SSOL_RS07245	COG3276	selenocysteine insertion sequence binding
SSOL_RS07255	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SSOL_RS07260	COG0556	nucleotide-excision repair
SSOL_RS07270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SSOL_RS07290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SSOL_RS07295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SSOL_RS07305	COG0805	protein transport
SSOL_RS07315	COG4139	cobalamin transport
SSOL_RS07320	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SSOL_RS07325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SSOL_RS07340	COG0581	inorganic phosphate transmembrane transporter activity
SSOL_RS07365	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SSOL_RS07415	COG0495	leucyl-tRNA aminoacylation
SSOL_RS07710	COG0433	COG0433 Predicted ATPase
SSOL_RS07810	COG4974	Belongs to the 'phage' integrase family
SSOL_RS07855	COG0535	radical SAM domain protein
SSOL_RS07875	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SSOL_RS07925	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SSOL_RS07930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SSOL_RS07950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SSOL_RS07955	COG0589	response to stress
SSOL_RS07965	COG0126	phosphoglycerate kinase activity
SSOL_RS07975	COG0668	transmembrane transport
SSOL_RS08000	COG0417	DNA replication proofreading
SSOL_RS08030	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SSOL_RS08050	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
SSOL_RS08060	COG1394	ATPase activity, coupled to movement of substances
SSOL_RS08075	COG0442	prolyl-tRNA aminoacylation
SSOL_RS08085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SSOL_RS08090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SSOL_RS08105	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SSOL_RS08115	COG0028	Belongs to the TPP enzyme family
SSOL_RS08125	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SSOL_RS08135	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SSOL_RS08150	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SSOL_RS08160	COG0037	tRNA processing
SSOL_RS08165	COG2096	Adenosyltransferase
SSOL_RS08170	COG0495	leucyl-tRNA aminoacylation
SSOL_RS08180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SSOL_RS08185	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SSOL_RS08190	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SSOL_RS08195	COG0131	Imidazoleglycerol-phosphate dehydratase
SSOL_RS08200	COG0107	imidazoleglycerol-phosphate synthase activity
SSOL_RS08205	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SSOL_RS08210	COG0140	phosphoribosyl-ATP diphosphatase activity
SSOL_RS08210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SSOL_RS08215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SSOL_RS08225	COG2151	metal-sulfur cluster biosynthetic enzyme
SSOL_RS08230	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SSOL_RS08235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SSOL_RS08250	COG1522	sequence-specific DNA binding
SSOL_RS08255	COG2095	MarC family integral membrane protein
SSOL_RS08270	COG0167	dihydroorotate dehydrogenase activity
SSOL_RS08285	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
SSOL_RS08295	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SSOL_RS08335	COG0602	queuosine metabolic process
SSOL_RS08340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SSOL_RS08345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SSOL_RS08345	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SSOL_RS08350	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SSOL_RS08360	COG0047	phosphoribosylformylglycinamidine synthase activity
SSOL_RS08365	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SSOL_RS08370	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SSOL_RS08375	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SSOL_RS08385	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SSOL_RS08400	COG0137	argininosuccinate synthase activity
SSOL_RS08405	COG0165	Argininosuccinate lyase
SSOL_RS08420	COG0189	ligase activity
SSOL_RS08430	COG1250	3-hydroxyacyl-CoA dehydrogenase
SSOL_RS08460	COG1024	Enoyl-CoA hydratase
SSOL_RS08475	COG0460	homoserine dehydrogenase
SSOL_RS08485	COG0864	Transcriptional regulator
SSOL_RS08490	COG0312	modulator of DNA gyrase
SSOL_RS08495	COG0312	modulator of DNA gyrase
SSOL_RS08500	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SSOL_RS08500	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SSOL_RS08505	COG0009	L-threonylcarbamoyladenylate synthase
SSOL_RS08510	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SSOL_RS08515	COG2379	hydroxypyruvate reductase
SSOL_RS08525	COG1321	iron dependent repressor
SSOL_RS08555	COG1763	Mo-molybdopterin cofactor biosynthetic process
SSOL_RS08560	COG0303	'Molybdopterin
SSOL_RS08575	COG0402	S-adenosylhomocysteine deaminase activity
SSOL_RS08590	COG0067	glutamate synthase
SSOL_RS08595	COG0069	glutamate synthase activity
SSOL_RS08605	COG0577	efflux transmembrane transporter activity
SSOL_RS08605	COG1136	(ABC) transporter
SSOL_RS08615	COG1136	(ABC) transporter
SSOL_RS08680	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SSOL_RS08700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SSOL_RS08705	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SSOL_RS08715	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SSOL_RS08725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SSOL_RS08730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SSOL_RS08735	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SSOL_RS08745	COG0255	Belongs to the universal ribosomal protein uL29 family
SSOL_RS08750	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SSOL_RS08755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SSOL_RS08760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SSOL_RS08765	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SSOL_RS08780	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SSOL_RS08795	COG0473	3-isopropylmalate dehydrogenase activity
SSOL_RS08815	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SSOL_RS08820	COG0322	excinuclease ABC activity
SSOL_RS08850	COG1185	polyribonucleotide nucleotidyltransferase activity
SSOL_RS08895	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SSOL_RS08905	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
SSOL_RS08910	COG2264	protein methyltransferase activity
SSOL_RS08915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SSOL_RS08950	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SSOL_RS08965	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SSOL_RS08980	COG1047	Peptidyl-prolyl cis-trans
SSOL_RS08985	COG0371	Dehydrogenase
SSOL_RS08990	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SSOL_RS09025	COG1063	alcohol dehydrogenase
SSOL_RS09030	COG0154	amidase activity
SSOL_RS09035	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SSOL_RS09040	COG1881	PFAM PEBP family protein
SSOL_RS09050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SSOL_RS09055	COG0315	cyclic pyranopterin monophosphate synthase activity
SSOL_RS09100	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SSOL_RS09115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SSOL_RS09170	COG0459	protein refolding
SSOL_RS09205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SSOL_RS09225	COG0460	homoserine dehydrogenase
SSOL_RS09225	COG0527	aspartate kinase activity
SSOL_RS09230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SSOL_RS09250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SSOL_RS09250	COG0574	Belongs to the PEP-utilizing enzyme family
SSOL_RS09255	COG1260	myo-inositol-1-phosphate synthase
SSOL_RS09260	COG1254	Belongs to the acylphosphatase family
SSOL_RS09265	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SSOL_RS09270	COG0159	tryptophan synthase activity
SSOL_RS09280	COG0135	phosphoribosylanthranilate isomerase activity
SSOL_RS09285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SSOL_RS09290	COG0512	Glutamine amidotransferase of anthranilate synthase
SSOL_RS09290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SSOL_RS09300	COG0436	Aminotransferase
SSOL_RS09305	COG0525	valine-tRNA ligase activity
SSOL_RS09310	COG0644	oxidoreductase
SSOL_RS09340	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
SSOL_RS09345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SSOL_RS09360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SSOL_RS09365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SSOL_RS09385	COG0148	phosphopyruvate hydratase activity
SSOL_RS09405	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SSOL_RS09415	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SSOL_RS09420	COG0509	glycine decarboxylation via glycine cleavage system
SSOL_RS09440	COG0396	ATPase activity
SSOL_RS09445	COG0719	Fe-S assembly protein
SSOL_RS09450	COG0719	Fe-S assembly protein
SSOL_RS09450	COG1372	Participates in initiation and elongation during chromosome replication
SSOL_RS09465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SSOL_RS09480	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SSOL_RS09485	COG0252	asparaginase activity
SSOL_RS09515	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
SSOL_RS09570	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SSOL_RS09570	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SSOL_RS09585	COG0154	amidase activity
SSOL_RS09625	COG1110	DNA topoisomerase II activity
SSOL_RS09655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SSOL_RS09665	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SSOL_RS09670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SSOL_RS09685	COG1028	Short-chain dehydrogenase reductase Sdr
SSOL_RS09695	COG0528	UMP kinase activity
SSOL_RS09705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SSOL_RS09725	COG0469	pyruvate kinase activity
SSOL_RS09735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SSOL_RS09745	COG0297	glycogen (starch) synthase activity
SSOL_RS09755	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SSOL_RS09785	COG0157	Belongs to the NadC ModD family
SSOL_RS09790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SSOL_RS09795	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SSOL_RS09810	COG0395	ABC-type sugar transport system, permease component
SSOL_RS09830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SSOL_RS09845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SSOL_RS09850	COG0028	Belongs to the TPP enzyme family
SSOL_RS09865	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SSOL_RS09870	COG2897	thiosulfate sulfurtransferase activity
SSOL_RS09880	COG0651	ATP synthesis coupled electron transport
SSOL_RS09885	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SSOL_RS09890	COG0649	NAD binding
SSOL_RS09895	COG0651	ATP synthesis coupled electron transport
SSOL_RS09905	COG0650	Formate hydrogenlyase subunit 4
SSOL_RS09920	COG3383	formate dehydrogenase (NAD+) activity
SSOL_RS09925	COG0300	oxidoreductase activity
SSOL_RS09930	COG0725	ABC transporter, periplasmic molybdate-binding protein
SSOL_RS09935	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SSOL_RS09980	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SSOL_RS09995	COG1234	tRNA 3'-trailer cleavage
SSOL_RS10040	COG1185	polyribonucleotide nucleotidyltransferase activity
SSOL_RS10060	COG0004	ammonium transporteR
SSOL_RS10095	COG0095	Lipoate-protein ligase
SSOL_RS10100	COG0509	glycine decarboxylation via glycine cleavage system
SSOL_RS10120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SSOL_RS10125	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SSOL_RS10130	COG2005	Transcriptional regulator
SSOL_RS10145	COG0531	amino acid
SSOL_RS10175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SSOL_RS10175	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SSOL_RS10180	COG0517	IMP dehydrogenase activity
SSOL_RS10190	COG0114	fumarate hydratase activity
SSOL_RS10195	COG1136	(ABC) transporter
SSOL_RS10205	COG1136	(ABC) transporter
SSOL_RS10205	COG0577	efflux transmembrane transporter activity
SSOL_RS10210	COG1846	Transcriptional regulator
SSOL_RS10215	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SSOL_RS10220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SSOL_RS10265	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SSOL_RS10305	COG2271	Major facilitator Superfamily
SSOL_RS10315	COG0509	glycine decarboxylation via glycine cleavage system
SSOL_RS10345	COG1832	CoA-binding protein
SSOL_RS10350	COG0095	Lipoate-protein ligase
SSOL_RS10395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SSOL_RS10405	COG2210	Belongs to the sulfur carrier protein TusA family
SSOL_RS10410	COG0425	Belongs to the sulfur carrier protein TusA family
SSOL_RS10440	COG2048	Heterodisulfide reductase, subunit B
SSOL_RS10455	COG0475	glutathione-regulated potassium exporter activity
SSOL_RS10485	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SSOL_RS10490	COG0477	Major facilitator Superfamily
SSOL_RS10530	COG1960	acyl-CoA dehydrogenase activity
SSOL_RS10570	COG2814	Major facilitator Superfamily
SSOL_RS10590	COG3842	ATPase activity
SSOL_RS10595	COG3833	ABC-type maltose transport systems, permease component
SSOL_RS10600	COG1175	transmembrane transport
SSOL_RS10635	COG0436	Aminotransferase
SSOL_RS10670	COG2271	Major facilitator Superfamily
SSOL_RS10675	COG1335	isochorismatase
SSOL_RS10720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SSOL_RS10725	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SSOL_RS10735	COG2062	phosphohistidine phosphatase, SixA
SSOL_RS10790	COG1013	pyruvate-flavodoxin oxidoreductase activity
SSOL_RS10795	COG0674	pyruvate-flavodoxin oxidoreductase activity
SSOL_RS10830	COG0277	FAD linked oxidase domain protein
SSOL_RS10870	COG3608	succinylglutamate desuccinylase aspartoacylase
SSOL_RS10870	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SSOL_RS10910	COG3350	monooxygenase activity
SSOL_RS10935	COG2151	metal-sulfur cluster biosynthetic enzyme
SSOL_RS10995	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SSOL_RS10995	COG2050	protein possibly involved in aromatic compounds catabolism
SSOL_RS11000	COG2301	Belongs to the HpcH HpaI aldolase family
SSOL_RS11005	COG1802	Transcriptional regulator
SSOL_RS11020	COG2721	sulfolactate sulfo-lyase activity
SSOL_RS11025	COG2721	sulfolactate sulfo-lyase activity
SSOL_RS11045	COG1131	(ABC) transporter
SSOL_RS11050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SSOL_RS11065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SSOL_RS11080	COG0601	transmembrane transport
SSOL_RS11090	COG0444	Belongs to the ABC transporter superfamily
SSOL_RS11095	COG4608	Belongs to the ABC transporter superfamily
SSOL_RS11110	COG4608	Belongs to the ABC transporter superfamily
SSOL_RS11115	COG0444	Belongs to the ABC transporter superfamily
SSOL_RS11125	COG0601	transmembrane transport
SSOL_RS11150	COG1373	ATPase (AAA superfamily
SSOL_RS11195	COG1215	transferase activity, transferring glycosyl groups
SSOL_RS11225	COG4948	Mandelate Racemase Muconate Lactonizing
SSOL_RS11245	COG2814	Major facilitator Superfamily
SSOL_RS11335	COG1203	CRISPR-associated helicase, Cas3
SSOL_RS11385	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SSOL_RS11410	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SSOL_RS11445	COG0531	amino acid
SSOL_RS11455	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SSOL_RS11475	COG1373	ATPase (AAA superfamily
SSOL_RS11690	COG0813	purine-nucleoside phosphorylase activity
SSOL_RS11720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SSOL_RS11725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SSOL_RS11730	COG0022	dehydrogenase e1 component
SSOL_RS11735	COG3199	ATP-NAD kinase
SSOL_RS11740	COG0508	dehydrogenase complex catalyzes the overall conversion of
SSOL_RS11745	COG0277	FAD linked oxidase domain protein
SSOL_RS11750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SSOL_RS11755	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SSOL_RS11780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SSOL_RS11785	COG0477	Major facilitator Superfamily
SSOL_RS11860	COG2084	Dehydrogenase
SSOL_RS11875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SSOL_RS11940	COG0243	molybdopterin cofactor binding
SSOL_RS12000	COG1725	Transcriptional regulator
SSOL_RS12090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SSOL_RS12095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SSOL_RS12100	COG4279	zinc finger
SSOL_RS12145	COG1953	Uracil, thiamine, allantoin
SSOL_RS12290	COG0531	amino acid
SSOL_RS12300	COG3335	DDE superfamily endonuclease
SSOL_RS12370	COG0438	transferase activity, transferring glycosyl groups
SSOL_RS12540	COG1215	transferase activity, transferring glycosyl groups
SSOL_RS12545	COG1216	Glycosyl transferase, family 2
SSOL_RS12545	COG1442	glycosyl transferase family 8
SSOL_RS12555	COG1216	Glycosyl transferase, family 2
SSOL_RS12555	COG0463	Glycosyl transferase, family 2
SSOL_RS12670	COG2002	toxin-antitoxin pair type II binding
SSOL_RS12735	COG0425	Belongs to the sulfur carrier protein TusA family
SSOL_RS12905	COG1136	(ABC) transporter
SSOL_RS12905	COG0577	efflux transmembrane transporter activity
SSOL_RS12960	COG2151	metal-sulfur cluster biosynthetic enzyme
SSOL_RS12965	COG0589	response to stress
SSOL_RS12985	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SSOL_RS12995	COG0501	Belongs to the peptidase M48B family
SSOL_RS13005	COG0519	Catalyzes the synthesis of GMP from XMP
SSOL_RS13050	COG0535	radical SAM domain protein
SSOL_RS13055	COG0535	radical SAM domain protein
SSOL_RS13175	COG2897	thiosulfate sulfurtransferase activity
SSOL_RS13305	COG0513	Belongs to the DEAD box helicase family
SSOL_RS13335	COG1011	Hydrolase
SSOL_RS13340	COG4106	trans-aconitate 2-methyltransferase activity
SSOL_RS13390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SSOL_RS13395	COG1953	Uracil, thiamine, allantoin
SSOL_RS13400	COG0531	amino acid
SSOL_RS13405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SSOL_RS13415	COG2814	Major facilitator Superfamily
SSOL_RS13565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SSOL_RS13585	COG1131	(ABC) transporter
SSOL_RS13610	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SSOL_RS13615	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SSOL_RS13665	COG1473	amidohydrolase
SSOL_RS13780	COG1960	acyl-CoA dehydrogenase activity
SSOL_RS13790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SSOL_RS13820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SSOL_RS13825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SSOL_RS13830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SSOL_RS13865	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SSOL_RS13865	COG2146	nitrite reductase [NAD(P)H] activity
SSOL_RS13885	COG0412	Dienelactone hydrolase
SSOL_RS13935	COG0793	Belongs to the peptidase S41A family
SSOL_RS13935	COG4946	Tricorn protease homolog
SSOL_RS13940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SSOL_RS14045	COG1121	(ABC) transporter
SSOL_RS14060	COG1305	Transglutaminase-like
SSOL_RS14065	COG0450	alkyl hydroperoxide reductase
SSOL_RS14095	COG1620	l-lactate permease
SSOL_RS14120	COG0674	pyruvate-flavodoxin oxidoreductase activity
SSOL_RS14125	COG1013	pyruvate-flavodoxin oxidoreductase activity
SSOL_RS14130	COG1522	sequence-specific DNA binding
SSOL_RS14145	COG0477	Major facilitator Superfamily
SSOL_RS14155	COG1131	(ABC) transporter
SSOL_RS14250	COG0561	phosphatase activity
SSOL_RS14255	COG2264	protein methyltransferase activity
SSOL_RS14260	COG1011	Hydrolase
SSOL_RS14275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SSOL_RS14310	COG0494	nUDIX hydrolase
SSOL_RS14320	COG3253	May function as heme-dependent peroxidase
SSOL_RS14335	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SSOL_RS14340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SSOL_RS14340	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SSOL_RS14370	COG2226	methyltransferase
SSOL_RS14610	COG1131	(ABC) transporter
SSOL_RS14825	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SSOL_RS14875	COG0675	Transposase, IS605 OrfB family
SSOL_RS15010	COG0275	rRNA processing