locus-tag	class	description
SULA_RS00005	COG0538	isocitrate dehydrogenase activity
SULA_RS00025	COG2154	pterin-4-alpha-carbinolamine dehydratase
SULA_RS00105	COG1331	Highly conserved protein containing a thioredoxin domain
SULA_RS00110	COG1028	Short-chain dehydrogenase reductase Sdr
SULA_RS00115	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SULA_RS00125	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
SULA_RS00150	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SULA_RS00165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULA_RS00190	COG0492	ferredoxin-NADP+ reductase activity
SULA_RS00235	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
SULA_RS00260	COG0588	phosphoglycerate mutase activity
SULA_RS00290	COG1957	nucleoside hydrolase
SULA_RS00295	COG0735	belongs to the Fur family
SULA_RS00320	COG0497	DNA recombination
SULA_RS00340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SULA_RS00340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SULA_RS00345	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SULA_RS00350	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
SULA_RS00385	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULA_RS00430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SULA_RS00435	COG1573	uracil-dna glycosylase
SULA_RS00440	COG1028	Short-chain dehydrogenase reductase Sdr
SULA_RS00465	COG0215	cysteine-tRNA ligase activity
SULA_RS00470	COG2222	sugar isomerase
SULA_RS00480	COG0446	pyridine nucleotide-disulphide oxidoreductase
SULA_RS00490	COG0433	COG0433 Predicted ATPase
SULA_RS00500	COG1607	acyl-coa hydrolase
SULA_RS00515	COG0708	Exodeoxyribonuclease III
SULA_RS00520	COG0515	serine threonine protein kinase
SULA_RS00520	COG2815	serine threonine protein kinase
SULA_RS00585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SULA_RS00730	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SULA_RS00735	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SULA_RS00750	COG0189	ligase activity
SULA_RS00790	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SULA_RS00810	COG1053	succinate dehydrogenase
SULA_RS00830	COG2304	oxidoreductase activity
SULA_RS00835	COG0714	Associated with various cellular activities
SULA_RS00855	COG0083	homoserine kinase activity
SULA_RS00860	COG0626	cystathionine gamma-synthase activity
SULA_RS00900	COG0183	Belongs to the thiolase family
SULA_RS00905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SULA_RS00950	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SULA_RS00960	COG0351	phosphomethylpyrimidine kinase
SULA_RS00965	COG0314	molybdopterin synthase activity
SULA_RS01000	COG1131	(ABC) transporter
SULA_RS01005	COG1668	transmembrane transport
SULA_RS01025	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SULA_RS01030	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SULA_RS01060	COG0720	synthase
SULA_RS01075	COG0492	ferredoxin-NADP+ reductase activity
SULA_RS01080	COG0483	inositol monophosphate 1-phosphatase activity
SULA_RS01085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULA_RS01100	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SULA_RS01105	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULA_RS01105	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
SULA_RS01115	COG0071	Belongs to the small heat shock protein (HSP20) family
SULA_RS01175	COG0402	S-adenosylhomocysteine deaminase activity
SULA_RS01200	COG0430	RNA-3'-phosphate cyclase activity
SULA_RS01215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SULA_RS01220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULA_RS01230	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SULA_RS01240	COG1515	deoxyribonuclease V activity
SULA_RS01285	COG4581	dead DEAH box helicase
SULA_RS01290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SULA_RS01300	COG0439	Biotin carboxylase
SULA_RS01310	COG1116	anion transmembrane transporter activity
SULA_RS01315	COG0066	3-isopropylmalate dehydratase activity
SULA_RS01320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SULA_RS01325	COG0415	Belongs to the DNA photolyase family
SULA_RS01380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SULA_RS01400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SULA_RS01405	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SULA_RS01420	COG0045	succinate-CoA ligase (ADP-forming) activity
SULA_RS01490	COG1063	alcohol dehydrogenase
SULA_RS01495	COG0183	Belongs to the thiolase family
SULA_RS01500	COG1960	acyl-CoA dehydrogenase activity
SULA_RS01505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SULA_RS01510	COG1028	Short-chain dehydrogenase reductase Sdr
SULA_RS01515	COG1064	alcohol dehydrogenase
SULA_RS01535	COG1309	transcriptional regulator
SULA_RS01560	COG0318	PFAM AMP-dependent synthetase and ligase
SULA_RS01565	COG1960	acyl-CoA dehydrogenase activity
SULA_RS01570	COG1024	Enoyl-CoA hydratase
SULA_RS01575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SULA_RS01580	COG0477	Major facilitator Superfamily
SULA_RS01605	COG0657	acetylesterase activity
SULA_RS01615	COG0318	PFAM AMP-dependent synthetase and ligase
SULA_RS01625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SULA_RS01630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SULA_RS01635	COG0477	Major facilitator Superfamily
SULA_RS01655	COG0432	Pfam Uncharacterised protein family UPF0047
SULA_RS01665	COG1024	Enoyl-CoA hydratase
SULA_RS01675	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
SULA_RS01815	COG0477	Major facilitator Superfamily
SULA_RS01820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULA_RS01825	COG0778	Nitroreductase
SULA_RS01880	COG1489	DNA binding
SULA_RS01900	COG0750	zinc metalloprotease
SULA_RS01935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SULA_RS01940	COG0039	L-malate dehydrogenase activity
SULA_RS01945	COG2079	MmgE PrpD family protein
SULA_RS01950	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SULA_RS01955	COG0516	GMP reductase activity
SULA_RS01955	COG0517	IMP dehydrogenase activity
SULA_RS01960	COG0372	Belongs to the citrate synthase family
SULA_RS01975	COG0149	triose-phosphate isomerase activity
SULA_RS02005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SULA_RS02010	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SULA_RS02040	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SULA_RS02060	COG0438	transferase activity, transferring glycosyl groups
SULA_RS02075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SULA_RS02080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SULA_RS02090	COG4608	Belongs to the ABC transporter superfamily
SULA_RS02095	COG0444	Belongs to the ABC transporter superfamily
SULA_RS02100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULA_RS02105	COG0601	transmembrane transport
SULA_RS02140	COG0183	Belongs to the thiolase family
SULA_RS02225	COG1592	Rubrerythrin
SULA_RS02250	COG4555	ABC transporter
SULA_RS02260	COG2217	Heavy metal translocating P-type atpase
SULA_RS02320	COG1028	Short-chain dehydrogenase reductase Sdr
SULA_RS02325	COG4948	Mandelate Racemase Muconate Lactonizing
SULA_RS02365	COG0444	Belongs to the ABC transporter superfamily
SULA_RS02370	COG4608	Belongs to the ABC transporter superfamily
SULA_RS02375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SULA_RS02420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SULA_RS02460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULA_RS02470	COG2239	Acts as a magnesium transporter
SULA_RS02475	COG4946	Tricorn protease homolog
SULA_RS02475	COG1506	peptidase
SULA_RS02475	COG0823	Involved in the tonB-independent uptake of proteins
SULA_RS02480	COG0501	Belongs to the peptidase M48B family
SULA_RS02485	COG4274	PFAM GYD family protein
SULA_RS02530	COG2814	Major facilitator Superfamily
SULA_RS02535	COG3386	PFAM SMP-30 Gluconolaconase
SULA_RS02540	COG0813	purine-nucleoside phosphorylase activity
SULA_RS02575	COG0395	ABC-type sugar transport system, permease component
SULA_RS02580	COG2814	Major facilitator Superfamily
SULA_RS02585	COG1063	alcohol dehydrogenase
SULA_RS02595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULA_RS02670	COG1573	uracil-dna glycosylase
SULA_RS02695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULA_RS02705	COG0517	IMP dehydrogenase activity
SULA_RS02715	COG3387	PFAM Glycoside hydrolase 15-related
SULA_RS02775	COG3387	PFAM Glycoside hydrolase 15-related
SULA_RS02780	COG0438	transferase activity, transferring glycosyl groups
SULA_RS02785	COG1013	pyruvate-flavodoxin oxidoreductase activity
SULA_RS02790	COG0674	pyruvate-flavodoxin oxidoreductase activity
SULA_RS02795	COG1144	Oxidoreductase
SULA_RS02800	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SULA_RS02805	COG0437	4 iron, 4 sulfur cluster binding
SULA_RS02820	COG1960	acyl-CoA dehydrogenase activity
SULA_RS02830	COG2086	electron transfer activity
SULA_RS02840	COG0492	ferredoxin-NADP+ reductase activity
SULA_RS02860	COG0668	transmembrane transport
SULA_RS02865	COG0402	S-adenosylhomocysteine deaminase activity
SULA_RS02880	COG3962	Belongs to the TPP enzyme family
SULA_RS02885	COG0438	transferase activity, transferring glycosyl groups
SULA_RS02895	COG0644	oxidoreductase
SULA_RS02905	COG0589	response to stress
SULA_RS02910	COG0656	L-ascorbic acid biosynthetic process
SULA_RS02960	COG0668	transmembrane transport
SULA_RS02965	COG0586	Pfam SNARE associated Golgi protein
SULA_RS02975	COG3511	phospholipase C
SULA_RS03000	COG0437	4 iron, 4 sulfur cluster binding
SULA_RS03005	COG0243	molybdopterin cofactor binding
SULA_RS03030	COG1063	alcohol dehydrogenase
SULA_RS03050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SULA_RS03075	COG0318	PFAM AMP-dependent synthetase and ligase
SULA_RS03110	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SULA_RS03110	COG0674	pyruvate-flavodoxin oxidoreductase activity
SULA_RS03115	COG1013	pyruvate-flavodoxin oxidoreductase activity
SULA_RS03120	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SULA_RS03125	COG0644	oxidoreductase
SULA_RS03135	COG0574	Belongs to the PEP-utilizing enzyme family
SULA_RS03135	COG3848	Pyruvate phosphate dikinase
SULA_RS03140	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SULA_RS03150	COG3383	formate dehydrogenase (NAD+) activity
SULA_RS03190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULA_RS03240	COG0395	ABC-type sugar transport system, permease component
SULA_RS03245	COG3842	ATPase activity
SULA_RS03250	COG0477	Major facilitator Superfamily
SULA_RS03285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULA_RS03290	COG1584	GPR1 FUN34 yaaH family protein
SULA_RS03315	COG0281	malic enzyme
SULA_RS03325	COG1250	3-hydroxyacyl-CoA dehydrogenase
SULA_RS03340	COG0318	PFAM AMP-dependent synthetase and ligase
SULA_RS03345	COG1960	acyl-CoA dehydrogenase activity
SULA_RS03355	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SULA_RS03355	COG3608	succinylglutamate desuccinylase aspartoacylase
SULA_RS03410	COG2217	Heavy metal translocating P-type atpase
SULA_RS03435	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SULA_RS03435	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SULA_RS03445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SULA_RS03485	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SULA_RS03605	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
SULA_RS03620	COG0477	Major facilitator Superfamily
SULA_RS03625	COG3473	Maleate cis-trans isomerase
SULA_RS03635	COG0179	Fumarylacetoacetate (FAA) hydrolase
SULA_RS03705	COG4608	Belongs to the ABC transporter superfamily
SULA_RS03710	COG0444	Belongs to the ABC transporter superfamily
SULA_RS03715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULA_RS03720	COG0601	transmembrane transport
SULA_RS03770	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SULA_RS03770	COG2857	Cytochrome c1
SULA_RS03785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SULA_RS03805	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SULA_RS03885	COG1914	H( )-stimulated, divalent metal cation uptake system
SULA_RS03890	COG1250	3-hydroxyacyl-CoA dehydrogenase
SULA_RS03895	COG4948	Mandelate Racemase Muconate Lactonizing
SULA_RS03900	COG0459	protein refolding
SULA_RS03915	COG1028	Short-chain dehydrogenase reductase Sdr
SULA_RS03930	COG0673	inositol 2-dehydrogenase activity
SULA_RS03950	COG1132	(ABC) transporter
SULA_RS03960	COG0667	Aldo Keto reductase
SULA_RS03985	COG2723	6-phospho-beta-galactosidase activity
SULA_RS03995	COG1501	Belongs to the glycosyl hydrolase 31 family
SULA_RS04045	COG1472	Belongs to the glycosyl hydrolase 3 family
SULA_RS04065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SULA_RS04070	COG3250	beta-galactosidase activity
SULA_RS04090	COG3386	PFAM SMP-30 Gluconolaconase
SULA_RS04105	COG4608	Belongs to the ABC transporter superfamily
SULA_RS04110	COG0444	Belongs to the ABC transporter superfamily
SULA_RS04115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULA_RS04125	COG0673	inositol 2-dehydrogenase activity
SULA_RS04155	COG0667	Aldo Keto reductase
SULA_RS04205	COG0318	PFAM AMP-dependent synthetase and ligase
SULA_RS04220	COG0395	ABC-type sugar transport system, permease component
SULA_RS04225	COG3842	ATPase activity
SULA_RS04235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SULA_RS04305	COG1136	(ABC) transporter
SULA_RS04325	COG0425	Belongs to the sulfur carrier protein TusA family
SULA_RS04365	COG1122	ATPase activity
SULA_RS04410	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SULA_RS04425	COG0805	protein transport
SULA_RS04455	COG1028	Short-chain dehydrogenase reductase Sdr
SULA_RS04465	COG2267	carboxylic ester hydrolase activity
SULA_RS04475	COG0179	Fumarylacetoacetate (FAA) hydrolase
SULA_RS04480	COG2271	Major facilitator Superfamily
SULA_RS04495	COG4948	Mandelate Racemase Muconate Lactonizing
SULA_RS04520	COG2814	Major facilitator Superfamily
SULA_RS04525	COG1139	Iron-sulfur cluster binding protein
SULA_RS04535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SULA_RS04550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SULA_RS04580	COG2271	Major facilitator Superfamily
SULA_RS04610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULA_RS04645	COG0655	NAD(P)H dehydrogenase (quinone) activity
SULA_RS04660	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SULA_RS04665	COG0095	Lipoate-protein ligase
SULA_RS04670	COG0247	lactate metabolic process
SULA_RS04675	COG0277	FAD linked oxidase domain protein
SULA_RS04715	COG1720	tRNA m6t6A37 methyltransferase activity
SULA_RS04730	COG0516	GMP reductase activity
SULA_RS04730	COG0517	IMP dehydrogenase activity
SULA_RS04740	COG1733	regulation of RNA biosynthetic process
SULA_RS04760	COG2814	Major facilitator Superfamily
SULA_RS04770	COG0515	serine threonine protein kinase
SULA_RS04770	COG2815	serine threonine protein kinase
SULA_RS04775	COG0589	response to stress
SULA_RS04780	COG0833	amino acid
SULA_RS04810	COG0243	molybdopterin cofactor binding
SULA_RS04815	COG0530	calcium, potassium:sodium antiporter activity
SULA_RS04820	COG1012	belongs to the aldehyde dehydrogenase family
SULA_RS04830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SULA_RS04835	COG4948	Mandelate Racemase Muconate Lactonizing
SULA_RS04850	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SULA_RS04860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULA_RS04865	COG1063	alcohol dehydrogenase
SULA_RS04870	COG0516	GMP reductase activity
SULA_RS04870	COG0517	IMP dehydrogenase activity
SULA_RS04890	COG0656	L-ascorbic acid biosynthetic process
SULA_RS04905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SULA_RS04920	COG1444	tRNA N-acetyltransferase activity
SULA_RS04935	COG0405	Gamma-glutamyltransferase
SULA_RS04970	COG1830	Aldolase
SULA_RS04980	COG0516	GMP reductase activity
SULA_RS04980	COG0517	IMP dehydrogenase activity
SULA_RS04985	COG0501	Belongs to the peptidase M48B family
SULA_RS04990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SULA_RS04990	COG0519	Catalyzes the synthesis of GMP from XMP
SULA_RS05000	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SULA_RS05010	COG1063	alcohol dehydrogenase
SULA_RS05030	COG0463	Glycosyl transferase, family 2
SULA_RS05080	COG1215	transferase activity, transferring glycosyl groups
SULA_RS05090	COG0351	phosphomethylpyrimidine kinase
SULA_RS05090	COG0352	thiamine-phosphate diphosphorylase activity
SULA_RS05095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SULA_RS05115	COG0123	including yeast histone deacetylase and acetoin utilization protein
SULA_RS05130	COG2860	membrane
SULA_RS05155	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SULA_RS05165	COG1201	RNA secondary structure unwinding
SULA_RS05210	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SULA_RS05220	COG0617	tRNA 3'-terminal CCA addition
SULA_RS05220	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SULA_RS05220	COG3620	sequence-specific DNA binding
SULA_RS05240	COG1192	Involved in chromosome partitioning
SULA_RS05340	COG1131	(ABC) transporter
SULA_RS05395	COG1304	FMN binding
SULA_RS05410	COG1355	regulation of microtubule-based process
SULA_RS05415	COG0052	Belongs to the universal ribosomal protein uS2 family
SULA_RS05425	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SULA_RS05430	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SULA_RS05435	COG0200	Binds to the 23S rRNA
SULA_RS05445	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SULA_RS05450	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SULA_RS05455	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SULA_RS05470	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SULA_RS05485	COG0456	acetyltransferase
SULA_RS05485	COG1214	PFAM Peptidase M22, glycoprotease
SULA_RS05510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SULA_RS05515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SULA_RS05530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SULA_RS05535	COG0561	phosphatase activity
SULA_RS05540	COG1078	dGTPase activity
SULA_RS05565	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SULA_RS05580	COG2267	carboxylic ester hydrolase activity
SULA_RS05585	COG1546	Belongs to the CinA family
SULA_RS05585	COG1058	Belongs to the CinA family
SULA_RS05590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SULA_RS05615	COG0517	IMP dehydrogenase activity
SULA_RS05615	COG0617	tRNA 3'-terminal CCA addition
SULA_RS05615	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SULA_RS05620	COG1201	RNA secondary structure unwinding
SULA_RS05635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SULA_RS05690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SULA_RS05795	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SULA_RS05840	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SULA_RS05845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SULA_RS05860	COG0189	ligase activity
SULA_RS05865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SULA_RS05870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULA_RS05875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SULA_RS05900	COG1129	ABC transporter
SULA_RS05915	COG0028	Belongs to the TPP enzyme family
SULA_RS05930	COG0017	Asparaginyl-tRNA synthetase
SULA_RS05935	COG0585	pseudouridine synthase activity
SULA_RS05955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULA_RS05970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SULA_RS05970	COG1648	precorrin-2 dehydrogenase activity
SULA_RS05975	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SULA_RS05980	COG0113	porphobilinogen synthase activity
SULA_RS05985	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SULA_RS05990	COG0181	hydroxymethylbilane synthase activity
SULA_RS06015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULA_RS06025	COG1793	dna ligase
SULA_RS06030	COG0717	Belongs to the dCTP deaminase family
SULA_RS06075	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
SULA_RS06090	COG0504	CTP synthase activity
SULA_RS06095	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SULA_RS06115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SULA_RS06125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SULA_RS06130	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SULA_RS06170	COG0051	transcription antitermination factor activity, RNA binding
SULA_RS06175	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SULA_RS06180	COG0049	tRNA binding
SULA_RS06205	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SULA_RS06210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SULA_RS06215	COG0085	RNA polymerase activity
SULA_RS06245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SULA_RS06250	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SULA_RS06265	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SULA_RS06280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SULA_RS06295	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SULA_RS06310	COG1605	Chorismate mutase
SULA_RS06310	COG0077	Prephenate dehydratase
SULA_RS06335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SULA_RS06335	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SULA_RS06350	COG1051	belongs to the nudix hydrolase family
SULA_RS06350	COG1056	cytidyltransferase-related domain
SULA_RS06385	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SULA_RS06425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SULA_RS06435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULA_RS06450	COG0343	queuine tRNA-ribosyltransferase activity
SULA_RS06470	COG0124	histidyl-tRNA synthetase
SULA_RS06485	COG0459	protein refolding
SULA_RS06510	COG1980	fructose-bisphosphate aldolase activity
SULA_RS06515	COG1121	(ABC) transporter
SULA_RS06525	COG0477	Major facilitator Superfamily
SULA_RS06550	COG1185	polyribonucleotide nucleotidyltransferase activity
SULA_RS06560	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SULA_RS06580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SULA_RS06585	COG3959	Transketolase, thiamine diphosphate binding domain
SULA_RS06590	COG3958	Transketolase
SULA_RS06595	COG0077	Prephenate dehydratase
SULA_RS06595	COG1605	Chorismate mutase
SULA_RS06600	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SULA_RS06605	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SULA_RS06610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SULA_RS06615	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SULA_RS06625	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SULA_RS06645	COG1199	ATP-dependent helicase activity
SULA_RS06665	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SULA_RS06670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SULA_RS06700	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULA_RS06705	COG0649	NAD binding
SULA_RS06710	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SULA_RS06715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULA_RS06725	COG0713	ATP synthesis coupled electron transport
SULA_RS06730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SULA_RS06735	COG1007	ATP synthesis coupled electron transport
SULA_RS06740	COG1260	myo-inositol-1-phosphate synthase
SULA_RS06745	COG0301	tRNA thio-modification
SULA_RS06775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SULA_RS06785	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SULA_RS06795	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SULA_RS06810	COG0552	protein localization to endoplasmic reticulum
SULA_RS06875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SULA_RS06890	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SULA_RS06900	COG0302	gtp cyclohydrolase
SULA_RS06920	COG3118	belongs to the thioredoxin family
SULA_RS06925	COG0318	PFAM AMP-dependent synthetase and ligase
SULA_RS06940	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SULA_RS06945	COG0535	radical SAM domain protein
SULA_RS06955	COG0475	glutathione-regulated potassium exporter activity
SULA_RS06985	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SULA_RS07000	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SULA_RS07005	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SULA_RS07025	COG0438	transferase activity, transferring glycosyl groups
SULA_RS07050	COG1444	tRNA N-acetyltransferase activity
SULA_RS07060	COG2813	Specifically methylates the guanine in position
SULA_RS07065	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SULA_RS07070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SULA_RS07080	COG1201	RNA secondary structure unwinding
SULA_RS07100	COG0402	S-adenosylhomocysteine deaminase activity
SULA_RS07110	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SULA_RS07130	COG1797	cobyrinic acid a,c-diamide synthase activity
SULA_RS07145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SULA_RS07175	COG0539	negative regulation of cytoplasmic translation
SULA_RS07190	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
SULA_RS07195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULA_RS07200	COG1110	DNA topoisomerase II activity
SULA_RS07225	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SULA_RS07245	COG0667	Aldo Keto reductase
SULA_RS07250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SULA_RS07260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SULA_RS07270	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
SULA_RS07275	COG0163	prenyltransferase activity
SULA_RS07305	COG0423	glycine-tRNA ligase activity
SULA_RS07310	COG0010	Belongs to the arginase family
SULA_RS07345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SULA_RS07355	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SULA_RS07385	COG1280	lysine exporter protein (LysE YggA)
SULA_RS07405	COG0489	protein tyrosine kinase activity
SULA_RS07445	COG0351	phosphomethylpyrimidine kinase
SULA_RS07445	COG1992	Thiamine-phosphate synthase
SULA_RS07465	COG3276	selenocysteine insertion sequence binding
SULA_RS07475	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
SULA_RS07480	COG0556	nucleotide-excision repair
SULA_RS07490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SULA_RS07510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SULA_RS07515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SULA_RS07525	COG0805	protein transport
SULA_RS07535	COG4139	cobalamin transport
SULA_RS07540	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
SULA_RS07545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SULA_RS07560	COG0581	inorganic phosphate transmembrane transporter activity
SULA_RS07585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SULA_RS07635	COG0495	leucyl-tRNA aminoacylation
SULA_RS07930	COG0433	COG0433 Predicted ATPase
SULA_RS08030	COG4974	Belongs to the 'phage' integrase family
SULA_RS08075	COG0535	radical SAM domain protein
SULA_RS08095	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SULA_RS08145	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SULA_RS08150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SULA_RS08170	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SULA_RS08175	COG0589	response to stress
SULA_RS08185	COG0126	phosphoglycerate kinase activity
SULA_RS08195	COG0668	transmembrane transport
SULA_RS08220	COG0417	DNA replication proofreading
SULA_RS08250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SULA_RS08270	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
SULA_RS08280	COG1394	ATPase activity, coupled to movement of substances
SULA_RS08295	COG0442	prolyl-tRNA aminoacylation
SULA_RS08305	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SULA_RS08310	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SULA_RS08325	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SULA_RS08335	COG0028	Belongs to the TPP enzyme family
SULA_RS08345	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SULA_RS08355	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SULA_RS08370	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SULA_RS08380	COG0037	tRNA processing
SULA_RS08385	COG2096	Adenosyltransferase
SULA_RS08390	COG0495	leucyl-tRNA aminoacylation
SULA_RS08400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SULA_RS08405	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SULA_RS08410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SULA_RS08415	COG0131	Imidazoleglycerol-phosphate dehydratase
SULA_RS08420	COG0107	imidazoleglycerol-phosphate synthase activity
SULA_RS08425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SULA_RS08430	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SULA_RS08430	COG0140	phosphoribosyl-ATP diphosphatase activity
SULA_RS08435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SULA_RS08445	COG2151	metal-sulfur cluster biosynthetic enzyme
SULA_RS08450	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SULA_RS08455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SULA_RS08470	COG1522	sequence-specific DNA binding
SULA_RS08475	COG2095	MarC family integral membrane protein
SULA_RS08490	COG0167	dihydroorotate dehydrogenase activity
SULA_RS08505	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
SULA_RS08515	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SULA_RS08555	COG0602	queuosine metabolic process
SULA_RS08560	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SULA_RS08565	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SULA_RS08565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SULA_RS08570	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SULA_RS08580	COG0047	phosphoribosylformylglycinamidine synthase activity
SULA_RS08585	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SULA_RS08590	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SULA_RS08595	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SULA_RS08605	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SULA_RS08620	COG0137	argininosuccinate synthase activity
SULA_RS08625	COG0165	Argininosuccinate lyase
SULA_RS08640	COG0189	ligase activity
SULA_RS08650	COG1250	3-hydroxyacyl-CoA dehydrogenase
SULA_RS08680	COG1024	Enoyl-CoA hydratase
SULA_RS08695	COG0460	homoserine dehydrogenase
SULA_RS08705	COG0864	Transcriptional regulator
SULA_RS08710	COG0312	modulator of DNA gyrase
SULA_RS08715	COG0312	modulator of DNA gyrase
SULA_RS08720	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SULA_RS08720	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SULA_RS08725	COG0009	L-threonylcarbamoyladenylate synthase
SULA_RS08730	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULA_RS08735	COG2379	hydroxypyruvate reductase
SULA_RS08745	COG1321	iron dependent repressor
SULA_RS08775	COG1763	Mo-molybdopterin cofactor biosynthetic process
SULA_RS08780	COG0303	'Molybdopterin
SULA_RS08795	COG0402	S-adenosylhomocysteine deaminase activity
SULA_RS08810	COG0067	glutamate synthase
SULA_RS08815	COG0069	glutamate synthase activity
SULA_RS08825	COG1136	(ABC) transporter
SULA_RS08825	COG0577	efflux transmembrane transporter activity
SULA_RS08835	COG1136	(ABC) transporter
SULA_RS08900	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SULA_RS08920	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SULA_RS08925	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SULA_RS08935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SULA_RS08945	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SULA_RS08950	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SULA_RS08955	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SULA_RS08965	COG0255	Belongs to the universal ribosomal protein uL29 family
SULA_RS08970	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SULA_RS08975	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SULA_RS08980	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SULA_RS08985	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SULA_RS09000	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SULA_RS09015	COG0473	3-isopropylmalate dehydrogenase activity
SULA_RS09035	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SULA_RS09040	COG0322	excinuclease ABC activity
SULA_RS09070	COG1185	polyribonucleotide nucleotidyltransferase activity
SULA_RS09115	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SULA_RS09125	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
SULA_RS09130	COG2264	protein methyltransferase activity
SULA_RS09135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SULA_RS09170	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SULA_RS09185	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SULA_RS09200	COG1047	Peptidyl-prolyl cis-trans
SULA_RS09205	COG0371	Dehydrogenase
SULA_RS09210	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SULA_RS09245	COG1063	alcohol dehydrogenase
SULA_RS09250	COG0154	amidase activity
SULA_RS09255	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
SULA_RS09260	COG1881	PFAM PEBP family protein
SULA_RS09270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SULA_RS09275	COG0315	cyclic pyranopterin monophosphate synthase activity
SULA_RS09320	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SULA_RS09335	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SULA_RS09390	COG0459	protein refolding
SULA_RS09425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SULA_RS09445	COG0460	homoserine dehydrogenase
SULA_RS09445	COG0527	aspartate kinase activity
SULA_RS09450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SULA_RS09470	COG0574	Belongs to the PEP-utilizing enzyme family
SULA_RS09470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SULA_RS09475	COG1260	myo-inositol-1-phosphate synthase
SULA_RS09480	COG1254	Belongs to the acylphosphatase family
SULA_RS09485	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SULA_RS09490	COG0159	tryptophan synthase activity
SULA_RS09500	COG0135	phosphoribosylanthranilate isomerase activity
SULA_RS09505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SULA_RS09510	COG0512	Glutamine amidotransferase of anthranilate synthase
SULA_RS09510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SULA_RS09520	COG0436	Aminotransferase
SULA_RS09525	COG0525	valine-tRNA ligase activity
SULA_RS09530	COG0644	oxidoreductase
SULA_RS09560	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
SULA_RS09565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SULA_RS09580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SULA_RS09585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULA_RS09605	COG0148	phosphopyruvate hydratase activity
SULA_RS09625	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SULA_RS09635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SULA_RS09640	COG0509	glycine decarboxylation via glycine cleavage system
SULA_RS09660	COG0396	ATPase activity
SULA_RS09665	COG0719	Fe-S assembly protein
SULA_RS09670	COG1372	Participates in initiation and elongation during chromosome replication
SULA_RS09670	COG0719	Fe-S assembly protein
SULA_RS09685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SULA_RS09700	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SULA_RS09705	COG0252	asparaginase activity
SULA_RS09735	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
SULA_RS09790	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SULA_RS09790	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SULA_RS09805	COG0154	amidase activity
SULA_RS09845	COG1110	DNA topoisomerase II activity
SULA_RS09875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SULA_RS09885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SULA_RS09890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SULA_RS09905	COG1028	Short-chain dehydrogenase reductase Sdr
SULA_RS09915	COG0528	UMP kinase activity
SULA_RS09925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SULA_RS09945	COG0469	pyruvate kinase activity
SULA_RS09955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULA_RS09965	COG0297	glycogen (starch) synthase activity
SULA_RS09975	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SULA_RS10005	COG0157	Belongs to the NadC ModD family
SULA_RS10010	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SULA_RS10015	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SULA_RS10030	COG0395	ABC-type sugar transport system, permease component
SULA_RS10050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULA_RS10065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULA_RS10070	COG0028	Belongs to the TPP enzyme family
SULA_RS10085	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SULA_RS10090	COG2897	thiosulfate sulfurtransferase activity
SULA_RS10100	COG0651	ATP synthesis coupled electron transport
SULA_RS10105	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULA_RS10110	COG0649	NAD binding
SULA_RS10115	COG0651	ATP synthesis coupled electron transport
SULA_RS10125	COG0650	Formate hydrogenlyase subunit 4
SULA_RS10140	COG3383	formate dehydrogenase (NAD+) activity
SULA_RS10145	COG0300	oxidoreductase activity
SULA_RS10150	COG0725	ABC transporter, periplasmic molybdate-binding protein
SULA_RS10155	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
SULA_RS10200	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SULA_RS10215	COG1234	tRNA 3'-trailer cleavage
SULA_RS10260	COG1185	polyribonucleotide nucleotidyltransferase activity
SULA_RS10275	COG0004	ammonium transporteR
SULA_RS10310	COG0095	Lipoate-protein ligase
SULA_RS10315	COG0509	glycine decarboxylation via glycine cleavage system
SULA_RS10335	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SULA_RS10340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SULA_RS10345	COG2005	Transcriptional regulator
SULA_RS10360	COG0531	amino acid
SULA_RS10390	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SULA_RS10390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SULA_RS10395	COG0517	IMP dehydrogenase activity
SULA_RS10405	COG0114	fumarate hydratase activity
SULA_RS10410	COG1136	(ABC) transporter
SULA_RS10425	COG1846	Transcriptional regulator
SULA_RS10430	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SULA_RS10435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SULA_RS10480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SULA_RS10520	COG2271	Major facilitator Superfamily
SULA_RS10530	COG0509	glycine decarboxylation via glycine cleavage system
SULA_RS10560	COG1832	CoA-binding protein
SULA_RS10565	COG0095	Lipoate-protein ligase
SULA_RS10610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULA_RS10620	COG2210	Belongs to the sulfur carrier protein TusA family
SULA_RS10625	COG0425	Belongs to the sulfur carrier protein TusA family
SULA_RS10655	COG2048	Heterodisulfide reductase, subunit B
SULA_RS10670	COG0475	glutathione-regulated potassium exporter activity
SULA_RS10700	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SULA_RS10705	COG0477	Major facilitator Superfamily
SULA_RS10745	COG1960	acyl-CoA dehydrogenase activity
SULA_RS10785	COG2814	Major facilitator Superfamily
SULA_RS10805	COG3842	ATPase activity
SULA_RS10810	COG3833	ABC-type maltose transport systems, permease component
SULA_RS10815	COG1175	transmembrane transport
SULA_RS10850	COG0436	Aminotransferase
SULA_RS10885	COG2271	Major facilitator Superfamily
SULA_RS10890	COG1335	isochorismatase
SULA_RS10935	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SULA_RS10940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SULA_RS10950	COG2062	phosphohistidine phosphatase, SixA
SULA_RS11005	COG1013	pyruvate-flavodoxin oxidoreductase activity
SULA_RS11010	COG0674	pyruvate-flavodoxin oxidoreductase activity
SULA_RS11045	COG0277	FAD linked oxidase domain protein
SULA_RS11085	COG3608	succinylglutamate desuccinylase aspartoacylase
SULA_RS11085	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
SULA_RS11125	COG3350	monooxygenase activity
SULA_RS11150	COG2151	metal-sulfur cluster biosynthetic enzyme
SULA_RS11210	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SULA_RS11210	COG2050	protein possibly involved in aromatic compounds catabolism
SULA_RS11215	COG2301	Belongs to the HpcH HpaI aldolase family
SULA_RS11220	COG1802	Transcriptional regulator
SULA_RS11235	COG2721	sulfolactate sulfo-lyase activity
SULA_RS11240	COG2721	sulfolactate sulfo-lyase activity
SULA_RS11260	COG1131	(ABC) transporter
SULA_RS11265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SULA_RS11280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SULA_RS11295	COG0601	transmembrane transport
SULA_RS11305	COG0444	Belongs to the ABC transporter superfamily
SULA_RS11310	COG4608	Belongs to the ABC transporter superfamily
SULA_RS11325	COG4608	Belongs to the ABC transporter superfamily
SULA_RS11330	COG0444	Belongs to the ABC transporter superfamily
SULA_RS11340	COG0601	transmembrane transport
SULA_RS11365	COG1373	ATPase (AAA superfamily
SULA_RS11410	COG1215	transferase activity, transferring glycosyl groups
SULA_RS11440	COG4948	Mandelate Racemase Muconate Lactonizing
SULA_RS11460	COG2814	Major facilitator Superfamily
SULA_RS11550	COG1203	CRISPR-associated helicase, Cas3
SULA_RS11600	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
SULA_RS11625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SULA_RS11660	COG0531	amino acid
SULA_RS11670	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SULA_RS11690	COG1373	ATPase (AAA superfamily
SULA_RS11905	COG0813	purine-nucleoside phosphorylase activity
SULA_RS11935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULA_RS11940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SULA_RS11945	COG0022	dehydrogenase e1 component
SULA_RS11950	COG3199	ATP-NAD kinase
SULA_RS11955	COG0508	dehydrogenase complex catalyzes the overall conversion of
SULA_RS11960	COG0277	FAD linked oxidase domain protein
SULA_RS11965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SULA_RS11970	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
SULA_RS11995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULA_RS12000	COG0477	Major facilitator Superfamily
SULA_RS12075	COG2084	Dehydrogenase
SULA_RS12090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SULA_RS12155	COG0243	molybdopterin cofactor binding
SULA_RS12215	COG1725	Transcriptional regulator
SULA_RS12305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SULA_RS12310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SULA_RS12315	COG4279	zinc finger
SULA_RS12360	COG1953	Uracil, thiamine, allantoin
SULA_RS12495	COG0531	amino acid
SULA_RS12505	COG3335	DDE superfamily endonuclease
SULA_RS12575	COG0438	transferase activity, transferring glycosyl groups
SULA_RS12750	COG1215	transferase activity, transferring glycosyl groups
SULA_RS12755	COG1216	Glycosyl transferase, family 2
SULA_RS12755	COG1442	glycosyl transferase family 8
SULA_RS12765	COG1216	Glycosyl transferase, family 2
SULA_RS12765	COG0463	Glycosyl transferase, family 2
SULA_RS12880	COG2002	toxin-antitoxin pair type II binding
SULA_RS12945	COG0425	Belongs to the sulfur carrier protein TusA family
SULA_RS13120	COG0577	efflux transmembrane transporter activity
SULA_RS13120	COG1136	(ABC) transporter
SULA_RS13175	COG2151	metal-sulfur cluster biosynthetic enzyme
SULA_RS13180	COG0589	response to stress
SULA_RS13200	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SULA_RS13210	COG0501	Belongs to the peptidase M48B family
SULA_RS13220	COG0519	Catalyzes the synthesis of GMP from XMP
SULA_RS13265	COG0535	radical SAM domain protein
SULA_RS13270	COG0535	radical SAM domain protein
SULA_RS13390	COG2897	thiosulfate sulfurtransferase activity
SULA_RS13520	COG0513	Belongs to the DEAD box helicase family
SULA_RS13550	COG1011	Hydrolase
SULA_RS13555	COG4106	trans-aconitate 2-methyltransferase activity
SULA_RS13605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULA_RS13610	COG1953	Uracil, thiamine, allantoin
SULA_RS13615	COG0531	amino acid
SULA_RS13620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SULA_RS13630	COG2814	Major facilitator Superfamily
SULA_RS13780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SULA_RS13800	COG1131	(ABC) transporter
SULA_RS13825	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SULA_RS13830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SULA_RS13880	COG1473	amidohydrolase
SULA_RS13995	COG1960	acyl-CoA dehydrogenase activity
SULA_RS14005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SULA_RS14035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULA_RS14040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SULA_RS14045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SULA_RS14080	COG2146	nitrite reductase [NAD(P)H] activity
SULA_RS14080	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SULA_RS14100	COG0412	Dienelactone hydrolase
SULA_RS14150	COG4946	Tricorn protease homolog
SULA_RS14150	COG0793	Belongs to the peptidase S41A family
SULA_RS14155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SULA_RS14265	COG1121	(ABC) transporter
SULA_RS14280	COG1305	Transglutaminase-like
SULA_RS14285	COG0450	alkyl hydroperoxide reductase
SULA_RS14315	COG1620	l-lactate permease
SULA_RS14340	COG0674	pyruvate-flavodoxin oxidoreductase activity
SULA_RS14345	COG1013	pyruvate-flavodoxin oxidoreductase activity
SULA_RS14350	COG1522	sequence-specific DNA binding
SULA_RS14365	COG0477	Major facilitator Superfamily
SULA_RS14375	COG1131	(ABC) transporter
SULA_RS14470	COG0561	phosphatase activity
SULA_RS14475	COG2264	protein methyltransferase activity
SULA_RS14480	COG1011	Hydrolase
SULA_RS14495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SULA_RS14530	COG0494	nUDIX hydrolase
SULA_RS14540	COG3253	May function as heme-dependent peroxidase
SULA_RS14555	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SULA_RS14560	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SULA_RS14560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SULA_RS14590	COG2226	methyltransferase
SULA_RS14845	COG1131	(ABC) transporter
SULA_RS15060	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SULA_RS15115	COG0675	Transposase, IS605 OrfB family
SULA_RS15245	COG0275	rRNA processing