locus-tag	class	description
EWF20_RS00030	ENOG4108EHY	type IV secretion system
EWF20_RS00085	ENOG4105C3U	ABC transporter
EWF20_RS00090	ENOG4108JQ7	(ABC) transporter
EWF20_RS00110	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EWF20_RS00115	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EWF20_RS00120	ENOG4105C3U	ABC transporter
EWF20_RS00125	ENOG4108JQ7	(ABC) transporter
EWF20_RS00135	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
EWF20_RS00140	ENOG4105CE4	GlcNAc 6-P deacetylase
EWF20_RS00190	ENOG4105KHC	sulfurtransferase
EWF20_RS00200	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
EWF20_RS00205	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
EWF20_RS00210	ENOG4107RIQ	Sulfate adenylate transferase
EWF20_RS00240	ENOG4107QN2	dihydrolipoyl dehydrogenase
EWF20_RS00425	ENOG4105PEJ	SchA CurD domain protein
EWF20_RS00435	ENOG4105DP8	Major facilitator superfamily MFS_1
EWF20_RS00445	ENOG4105CPQ	Dehydrogenase
EWF20_RS00520	ENOG4105DQQ	Major facilitator superfamily MFS_1
EWF20_RS00530	ENOG4108IUE	nitrate reductase beta subunit
EWF20_RS00710	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
EWF20_RS00760	ENOG4105CSH	Transporter
EWF20_RS00765	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EWF20_RS00810	ENOG4105DCI	Phosphohydrolase
EWF20_RS00950	ENOG4105CUG	Oligopeptidase b
EWF20_RS00990	ENOG4105E39	Enoyl-CoA hydratase
EWF20_RS01015	ENOG4105CSH	Transporter
EWF20_RS01035	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
EWF20_RS01055	ENOG4105CEY	Amp-dependent synthetase and ligase
EWF20_RS01065	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
EWF20_RS01070	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
EWF20_RS01115	ENOG4107GD3	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity)
EWF20_RS01120	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EWF20_RS01130	ENOG4105C54	Major Facilitator superfamily
EWF20_RS01135	ENOG4105CXK	mandelate racemase muconate lactonizing
EWF20_RS01140	ENOG4105CEY	Amp-dependent synthetase and ligase
EWF20_RS01145	ENOG4108Z7G	MaoC domain protein dehydratase
EWF20_RS01155	ENOG4105CHU	acetyl-coa acetyltransferase
EWF20_RS01170	ENOG41069FQ	Metallo-beta-lactamase superfamily
EWF20_RS01180	ENOG4105C1G	acyl-Coa dehydrogenase
EWF20_RS01185	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
EWF20_RS01195	ENOG4105E39	Enoyl-CoA hydratase
EWF20_RS01215	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EWF20_RS01240	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EWF20_RS01250	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
EWF20_RS01285	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EWF20_RS01290	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
EWF20_RS01310	ENOG4105CPQ	Dehydrogenase
EWF20_RS01315	ENOG4105C1G	acyl-Coa dehydrogenase
EWF20_RS01320	ENOG4105CEY	Amp-dependent synthetase and ligase
EWF20_RS01325	ENOG4105CHU	acetyl-coa acetyltransferase
EWF20_RS01335	ENOG4108IEG	Formate dehydrogenase Alpha subunit
EWF20_RS01345	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
EWF20_RS01350	ENOG4105C1G	acyl-Coa dehydrogenase
EWF20_RS01360	ENOG4105CC9	acyl-Coa dehydrogenase
EWF20_RS01385	ENOG4105C54	Major Facilitator superfamily
EWF20_RS01395	ENOG4105C7W	Xanthine dehydrogenase
EWF20_RS01405	ENOG4106YT9	Enoyl-CoA hydratase
EWF20_RS01410	ENOG4105CHU	acetyl-coa acetyltransferase
EWF20_RS01425	ENOG4105D82	Glutamate dehydrogenase
EWF20_RS01440	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EWF20_RS01470	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EWF20_RS01485	ENOG4107WJM	-acetyltransferase
EWF20_RS01490	ENOG4105C6K	Malic enzyme
EWF20_RS01500	ENOG4105K4P	CoA-binding domain protein
EWF20_RS01550	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
EWF20_RS01555	ENOG4105CV8	reductase
EWF20_RS01590	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EWF20_RS01595	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EWF20_RS01630	ENOG4105C1J	atp-dependent rna helicase
EWF20_RS01675	ENOG4105C5F	glutamine synthetase
EWF20_RS01720	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EWF20_RS01765	ENOG4105D1F	ATP-binding protein
EWF20_RS01815	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
EWF20_RS01820	ENOG4107TSN	permease
EWF20_RS01840	ENOG4108IAJ	Nad-dependent epimerase dehydratase
EWF20_RS01865	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
EWF20_RS01870	ENOG4108KB0	deacetylase
EWF20_RS01875	ENOG4105C8Y	Acetylornithine aminotransferase
EWF20_RS01880	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EWF20_RS01895	ENOG4105CAS	nag kinase
EWF20_RS01900	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
EWF20_RS01915	ENOG41080HJ	6-phospho 3-hexuloisomerase
EWF20_RS01950	ENOG4105C7K	acetolactate synthase
EWF20_RS01975	ENOG4105C5S	asparaginyl-tRNA synthetase
EWF20_RS01980	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
EWF20_RS02000	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EWF20_RS02020	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
EWF20_RS02025	ENOG4105D52	delta-aminolevulinic acid dehydratase
EWF20_RS02030	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
EWF20_RS02035	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
EWF20_RS02060	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
EWF20_RS02070	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
EWF20_RS02090	ENOG4105NBF	ammecr1 domain protein
EWF20_RS02120	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
EWF20_RS02135	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EWF20_RS02140	ENOG4108VA3	3-hexulose-6-phosphate synthase
EWF20_RS02160	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
EWF20_RS02170	ENOG4105VUC	UPF0237 protein
EWF20_RS02235	ENOG4108PBA	serine threonine protein kinase
EWF20_RS02310	ENOG4105CIG	ABC transporter
EWF20_RS02330	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
EWF20_RS02335	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EWF20_RS02360	ENOG4105XPM	ribosomal protein
EWF20_RS02365	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EWF20_RS02370	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EWF20_RS02375	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EWF20_RS02385	ENOG4105C6K	Malic enzyme
EWF20_RS02390	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EWF20_RS02395	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
EWF20_RS02410	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
EWF20_RS02415	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EWF20_RS02420	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
EWF20_RS02430	ENOG4105WCJ	ec 1.1.1.193
EWF20_RS02435	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EWF20_RS02450	ENOG4105C83	adenylosuccinate lyase
EWF20_RS02465	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
EWF20_RS02480	ENOG4105CQC	Prephenate dehydratase
EWF20_RS02485	ENOG4105C7B	Threonine dehydratase
EWF20_RS02505	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EWF20_RS02525	ENOG4105NAU	thioesterase Superfamily protein
EWF20_RS02600	ENOG4108FPN	Integrase
EWF20_RS02630	ENOG4105FDK	ABC transporter
EWF20_RS02635	ENOG4107NFR	Fructose-1,6-bisphosphatase
EWF20_RS02660	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EWF20_RS02675	ENOG4105CUT	histidyl-tRNA synthetase
EWF20_RS02695	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
EWF20_RS02710	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EWF20_RS02720	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
EWF20_RS02765	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
EWF20_RS02775	ENOG4105CSH	Transporter
EWF20_RS02795	ENOG4105CY0	Metallo-Beta-Lactamase
EWF20_RS02800	ENOG4108MDK	Dehydrogenase
EWF20_RS02805	ENOG4108YZY	peptidylprolyl cis-trans isomerase
EWF20_RS02815	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
EWF20_RS02880	ENOG4105CJ1	ABC, transporter
EWF20_RS02905	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EWF20_RS02910	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EWF20_RS02925	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
EWF20_RS02945	ENOG4108ZJT	translation initiation factor, Sui1
EWF20_RS02960	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
EWF20_RS02990	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
EWF20_RS03000	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
EWF20_RS03015	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EWF20_RS03025	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
EWF20_RS03030	ENOG4105CPC	Aldo Keto reductase
EWF20_RS03075	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
EWF20_RS03080	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EWF20_RS03085	ENOG4105E3H	phosphoglycerate mutase
EWF20_RS03110	ENOG4105EM7	Selenocysteine-specific translation elongation factor
EWF20_RS03120	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
EWF20_RS03130	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
EWF20_RS03135	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
EWF20_RS03145	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
EWF20_RS03165	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
EWF20_RS03195	ENOG4107QRT	dEAD DEAH box helicase
EWF20_RS03205	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EWF20_RS03210	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EWF20_RS03215	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
EWF20_RS03225	ENOG41088YS	Glycosyl transferase (Group 1
EWF20_RS03320	ENOG4105CAT	Cytidine monophosphate kinase
EWF20_RS03345	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
EWF20_RS03355	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EWF20_RS03375	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EWF20_RS03380	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
EWF20_RS03405	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
EWF20_RS03425	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
EWF20_RS03430	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
EWF20_RS03435	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EWF20_RS03440	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EWF20_RS03445	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
EWF20_RS03450	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
EWF20_RS03455	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EWF20_RS03470	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EWF20_RS03490	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EWF20_RS03500	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
EWF20_RS03530	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EWF20_RS03570	ENOG4105C3G	gtp-binding protein
EWF20_RS03575	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
EWF20_RS03585	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
EWF20_RS03590	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EWF20_RS03595	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EWF20_RS03650	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EWF20_RS03710	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EWF20_RS03715	ENOG4105D1H	recombination factor protein RarA
EWF20_RS03725	ENOG4108V1U	phospholipid-binding protein
EWF20_RS03730	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
EWF20_RS03735	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
EWF20_RS03745	ENOG4105CPQ	Dehydrogenase
EWF20_RS03770	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
EWF20_RS03775	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
EWF20_RS03790	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EWF20_RS03795	ENOG4108VVK	transcriptional Regulator, AsnC
EWF20_RS03825	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
EWF20_RS03855	ENOG41086B8	CoB-CoM heterodisulfide reductase
EWF20_RS03870	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
EWF20_RS03885	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EWF20_RS03890	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
EWF20_RS03895	ENOG4105C28	cystathionine
EWF20_RS03940	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EWF20_RS03995	ENOG4105DWF	phosphomethylpyrimidine kinase
EWF20_RS04000	ENOG4108ZAF	Molybdopterin
EWF20_RS04065	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EWF20_RS04115	ENOG4105ECY	inositol monophosphatase
EWF20_RS04120	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EWF20_RS04135	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
EWF20_RS04160	ENOG4105EM7	Selenocysteine-specific translation elongation factor
EWF20_RS04175	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
EWF20_RS04195	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EWF20_RS04240	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
EWF20_RS04250	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
EWF20_RS04255	ENOG4108RVA	ribokinase
EWF20_RS04265	ENOG4108Z4K	mutator MutT protein
EWF20_RS04270	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EWF20_RS04275	ENOG4105EHU	Circadian clock protein KaiC
EWF20_RS04280	ENOG410641W	Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear
EWF20_RS04285	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
EWF20_RS04290	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
EWF20_RS04300	ENOG4105D3R	alkyl hydroperoxide reductase
EWF20_RS04315	ENOG4105BZN	citrate synthase
EWF20_RS04350	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EWF20_RS04360	ENOG4105D7T	ABC transporter
EWF20_RS04375	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
EWF20_RS04380	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EWF20_RS04385	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EWF20_RS04390	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
EWF20_RS04420	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
EWF20_RS04430	ENOG4105CJ1	ABC, transporter
EWF20_RS04445	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EWF20_RS04520	ENOG4105C8T	Leucyl-tRNA synthetase
EWF20_RS04530	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EWF20_RS04550	ENOG4107R56	PP-loop domain protein
EWF20_RS04560	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EWF20_RS04640	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
EWF20_RS04645	ENOG4105CQB	FAD linked oxidase domain protein
EWF20_RS04655	ENOG4105CEP	NADH dehydrogenase
EWF20_RS04700	ENOG4105BZU	Histidine kinase
EWF20_RS04740	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
EWF20_RS04765	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EWF20_RS04770	ENOG4105BZ9	Cytochrome C oxidase, subunit I
EWF20_RS04800	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EWF20_RS04815	ENOG4107QPV	Serine Threonine protein kinase
EWF20_RS04820	ENOG4107QN2	dihydrolipoyl dehydrogenase
EWF20_RS04845	ENOG4107QNK	)-transporter
EWF20_RS04880	ENOG4108RCM	Nitroreductase
EWF20_RS04885	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
EWF20_RS04900	ENOG4108JQ7	(ABC) transporter
EWF20_RS04905	ENOG4105C3U	ABC transporter
EWF20_RS04910	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EWF20_RS04915	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EWF20_RS04950	ENOG4105D2S	major facilitator superfamily
EWF20_RS04970	ENOG4105DIK	(ABC) transporter
EWF20_RS05020	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EWF20_RS05040	ENOG4105EFA	4-hydroxyphenylacetate
EWF20_RS05050	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EWF20_RS05055	ENOG4106HK8	GPR1 FUN34 yaaH family protein
EWF20_RS05060	ENOG41067KJ	GYD family
EWF20_RS05075	ENOG4105C8Y	Acetylornithine aminotransferase
EWF20_RS05105	ENOG4105EKN	Major Facilitator
EWF20_RS05205	ENOG4105VG1	fes assembly suf system protein
EWF20_RS05250	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
EWF20_RS05270	ENOG4108IUW	ABC transporter
EWF20_RS05350	ENOG41080XP	Cbs domain
EWF20_RS05375	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EWF20_RS05395	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
EWF20_RS05410	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EWF20_RS05510	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
EWF20_RS05515	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
EWF20_RS05530	ENOG4105D9P	serine threonine protein kinase
EWF20_RS05540	ENOG4105KME	endoribonuclease L-psp
EWF20_RS05550	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EWF20_RS05565	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
EWF20_RS05575	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EWF20_RS05615	ENOG4105T58	Dithiol-disulfide isomerase
EWF20_RS05645	ENOG4107QM5	aconitate hydratase
EWF20_RS05660	ENOG4105D0M	Protease HtpX homolog
EWF20_RS05700	ENOG4108I9K	permease protein
EWF20_RS05705	ENOG4105FDK	ABC transporter
EWF20_RS05745	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EWF20_RS05780	ENOG4105CUB	amino acid
EWF20_RS05790	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EWF20_RS05820	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EWF20_RS05840	ENOG4105CS1	NAD(P)H quinone oxidoreductase
EWF20_RS05915	ENOG4107RA4	Glycosyl transferase (Group 1
EWF20_RS05950	ENOG4108Z0Z	intracellular protease Pfpi family
EWF20_RS05995	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EWF20_RS06005	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EWF20_RS06050	ENOG4105C0D	helicase
EWF20_RS06070	ENOG4106A3M	Cytochrome p-450
EWF20_RS06180	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EWF20_RS06195	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
EWF20_RS06200	ENOG4105BZP	glycoside hydrolase 15-related
EWF20_RS06365	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
EWF20_RS06375	ENOG4108Z7G	MaoC domain protein dehydratase
EWF20_RS06380	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
EWF20_RS06385	ENOG4105CHR	reductase
EWF20_RS06395	ENOG4105CNN	ABC, transporter
EWF20_RS06400	ENOG4105C2J	ABC transporter
EWF20_RS06440	ENOG4105CXK	mandelate racemase muconate lactonizing
EWF20_RS06445	ENOG4105CHR	reductase
EWF20_RS06460	ENOG4105DU0	nucleoside hydrolase
EWF20_RS06475	ENOG4107QNK	)-transporter
EWF20_RS06485	ENOG4105CEY	Amp-dependent synthetase and ligase
EWF20_RS06490	ENOG4105C8Y	Acetylornithine aminotransferase
EWF20_RS06535	ENOG4105K8R	UPF0145 protein
EWF20_RS06580	ENOG4107QN2	dihydrolipoyl dehydrogenase
EWF20_RS06615	ENOG4105DIK	(ABC) transporter
EWF20_RS06670	ENOG4108RDQ	ABC transporter
EWF20_RS06845	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
EWF20_RS06855	ENOG4107ZMQ	sugar fermentation stimulation protein
EWF20_RS06945	ENOG4105E3S	small subunit
EWF20_RS06980	ENOG4105C8H	hydrogenase maturation protein Hypf
EWF20_RS06990	ENOG4105KVH	Transcriptional regulator
EWF20_RS06995	ENOG4105DPX	Hydrogenase, large subunit
EWF20_RS07050	ENOG4105DPX	Hydrogenase, large subunit
EWF20_RS07110	ENOG4108JJB	ABC transporter
EWF20_RS07165	ENOG4105CEU	Arginine dihydrolase
EWF20_RS07170	ENOG4107S2W	Nitric oxide dioxygenase
EWF20_RS07180	ENOG4105DQQ	Major facilitator superfamily MFS_1
EWF20_RS07210	ENOG4105CQM	Urea amidohydrolase subunit alpha
EWF20_RS07225	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
EWF20_RS07235	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
EWF20_RS07245	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
EWF20_RS07255	ENOG4107YZX	Universal stress protein
EWF20_RS07330	ENOG4105C7W	Xanthine dehydrogenase
EWF20_RS07350	ENOG4105CD3	dihydroorotase
EWF20_RS07380	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
EWF20_RS07390	ENOG4105C8I	hydrolase, family 38
EWF20_RS07395	ENOG4105DWF	phosphomethylpyrimidine kinase
EWF20_RS07400	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EWF20_RS07450	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EWF20_RS07500	ENOG4108SZE	gCN5-related N-acetyltransferase
EWF20_RS07590	ENOG4105DCI	Phosphohydrolase
EWF20_RS07595	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
EWF20_RS07605	ENOG4105CPK	Glycosyl transferase (Group 1
EWF20_RS07610	ENOG4105BZP	glycoside hydrolase 15-related
EWF20_RS07620	ENOG4105CEP	NADH dehydrogenase
EWF20_RS07665	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
EWF20_RS07675	ENOG4105C22	threonyL-tRNA synthetase
EWF20_RS07685	ENOG4105CSM	endonuclease III
EWF20_RS07690	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
EWF20_RS07695	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
EWF20_RS07725	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
EWF20_RS07730	ENOG4105DB1	molybdopterin oxidoreductase
EWF20_RS07760	ENOG4105CQS	hydrogenase expression formation protein HypD
EWF20_RS07775	ENOG4105DPX	Hydrogenase, large subunit
EWF20_RS07850	ENOG4105M7V	2'-5' rna ligase
EWF20_RS07875	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
EWF20_RS07910	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EWF20_RS07935	ENOG4108IXY	short-chain dehydrogenase reductase
EWF20_RS07940	ENOG4108RE7	deoxyribonuclease
EWF20_RS07950	ENOG4105JHE	Major Facilitator Superfamily
EWF20_RS08015	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
EWF20_RS08025	ENOG4105C0H	protease
EWF20_RS08035	ENOG4105C1G	acyl-Coa dehydrogenase
EWF20_RS08060	ENOG4105C54	Major Facilitator superfamily
EWF20_RS08075	ENOG4107RE3	peptidase, S41
EWF20_RS08085	ENOG4107TE1	transport protein
EWF20_RS08095	ENOG4108EHY	type IV secretion system
EWF20_RS08220	ENOG4108IYU	L-aspartate oxidase
EWF20_RS08225	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
EWF20_RS08250	ENOG4105DIW	FeS assembly protein SUFB
EWF20_RS08255	ENOG4105C3K	feS assembly ATPase SufC
EWF20_RS08275	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
EWF20_RS08280	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EWF20_RS08285	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EWF20_RS08290	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EWF20_RS08305	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
EWF20_RS08325	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EWF20_RS08330	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
EWF20_RS08345	ENOG4108JQ1	Dehydrogenase
EWF20_RS08350	ENOG4105GRF	N-glycosylase DNA lyase
EWF20_RS08380	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
EWF20_RS08385	ENOG4105CHM	Aminotransferase
EWF20_RS08390	ENOG4105DK0	Indole-3-glycerol phosphate synthase
EWF20_RS08395	ENOG4105DDQ	anthranilate synthase
EWF20_RS08400	ENOG4105CRQ	synthase (Component I)
EWF20_RS08405	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
EWF20_RS08415	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
EWF20_RS08420	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
EWF20_RS08425	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
EWF20_RS08440	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
EWF20_RS08460	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
EWF20_RS08465	ENOG4105CFH	Aspartokinase
EWF20_RS08470	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
EWF20_RS08475	ENOG4105C0B	DNA polymerase III (alpha subunit)
EWF20_RS08485	ENOG4105DBV	ornithine carbamoyltransferase
EWF20_RS08520	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EWF20_RS08555	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EWF20_RS08570	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EWF20_RS08575	ENOG4105HDK	L-asparaginase
EWF20_RS08605	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
EWF20_RS08655	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
EWF20_RS08670	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
EWF20_RS08675	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EWF20_RS08680	ENOG4105VF7	tolerance protein
EWF20_RS08715	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
EWF20_RS08725	ENOG4107QRT	dEAD DEAH box helicase
EWF20_RS08775	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
EWF20_RS08795	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EWF20_RS08810	ENOG4105E66	phosphoriboisomerase A
EWF20_RS08830	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
EWF20_RS08850	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
EWF20_RS08875	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EWF20_RS08880	ENOG4107YZX	Universal stress protein
EWF20_RS08890	ENOG4105BZA	Phosphoglycerate kinase
EWF20_RS08925	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EWF20_RS08935	ENOG4108VZM	50s ribosomal protein L10
EWF20_RS08945	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EWF20_RS08960	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EWF20_RS09025	ENOG4105C6T	cysteine synthase
EWF20_RS09045	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EWF20_RS09050	ENOG4105DC7	peptidase M24
EWF20_RS09055	ENOG4105EUJ	GTP cyclohydrolase i
EWF20_RS09065	ENOG4105C5F	glutamine synthetase
EWF20_RS09070	ENOG4105K63	Thioredoxin
EWF20_RS09075	ENOG4105CEY	Amp-dependent synthetase and ligase
EWF20_RS09085	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EWF20_RS09090	ENOG4108Z0R	Transferase
EWF20_RS09100	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EWF20_RS09125	ENOG4107QHF	type ii secretion system protein e
EWF20_RS09160	ENOG4107R8N	Glycosyl transferase, family 2
EWF20_RS09165	ENOG4107QRT	dEAD DEAH box helicase
EWF20_RS09195	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EWF20_RS09200	ENOG4105CEV	competence damage-inducible protein
EWF20_RS09205	ENOG4105F2Z	3-oxoadipate enol-lactonase
EWF20_RS09220	ENOG4105E8R	UPF0173 metal-dependent hydrolase
EWF20_RS09250	ENOG4108KP7	hydrolase
EWF20_RS09255	ENOG4105CX6	glutaminyL-tRNA synthetase
EWF20_RS09275	ENOG4105CQ2	DNA polymerase
EWF20_RS09305	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EWF20_RS09325	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
EWF20_RS09335	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
EWF20_RS09360	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
EWF20_RS09365	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
EWF20_RS09380	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
EWF20_RS09390	ENOG4105C7K	acetolactate synthase
EWF20_RS09400	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
EWF20_RS09425	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
EWF20_RS09435	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
EWF20_RS09445	ENOG4105C8T	Leucyl-tRNA synthetase
EWF20_RS09455	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EWF20_RS09460	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
EWF20_RS09470	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
EWF20_RS09475	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
EWF20_RS09480	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
EWF20_RS09485	ENOG41083RF	phosphoribosyl-ATP pyrophosphatase
EWF20_RS09490	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
EWF20_RS09495	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
EWF20_RS09500	ENOG4105VG1	fes assembly suf system protein
EWF20_RS09505	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EWF20_RS09510	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EWF20_RS09520	ENOG4105K59	histidine triad (HIT) protein
EWF20_RS09530	ENOG4108VVK	transcriptional Regulator, AsnC
EWF20_RS09550	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
EWF20_RS09555	ENOG4105CD3	dihydroorotase
EWF20_RS09565	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
EWF20_RS09570	ENOG4105CXT	aspartate transcarbamylase
EWF20_RS09620	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
EWF20_RS09625	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EWF20_RS09630	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EWF20_RS09635	ENOG4105C8V	SAICAR synthetase
EWF20_RS09645	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
EWF20_RS09650	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
EWF20_RS09670	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
EWF20_RS09685	ENOG4105CDH	Citrulline--aspartate ligase
EWF20_RS09690	ENOG4105CH7	arginosuccinase
EWF20_RS09695	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
EWF20_RS09705	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EWF20_RS09715	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
EWF20_RS09760	ENOG4105E39	Enoyl-CoA hydratase
EWF20_RS09770	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
EWF20_RS09775	ENOG4105D6E	homoserine dehydrogenase
EWF20_RS09790	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
EWF20_RS09800	ENOG4107YZX	Universal stress protein
EWF20_RS09805	ENOG4108EKN	Biotin protein ligase C terminal domain
EWF20_RS09810	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EWF20_RS09815	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EWF20_RS09845	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
EWF20_RS09850	ENOG4105DDK	oxidoreductase, beta subunit
EWF20_RS09870	ENOG4105CD5	CoA-binding domain protein
EWF20_RS09915	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EWF20_RS09920	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EWF20_RS09925	ENOG4105C9X	ppx gppa phosphatase
EWF20_RS09935	ENOG4105D0M	Protease HtpX homolog
EWF20_RS09945	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EWF20_RS09965	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
EWF20_RS09970	ENOG4105DB1	molybdopterin oxidoreductase
EWF20_RS10075	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
EWF20_RS10205	ENOG4105E8R	UPF0173 metal-dependent hydrolase
EWF20_RS10220	ENOG4105CJ1	ABC, transporter
EWF20_RS10265	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
EWF20_RS10330	ENOG4105E4P	ATPase (AAA
EWF20_RS10525	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
EWF20_RS10535	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
EWF20_RS10540	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
EWF20_RS10555	ENOG4107QRS	glycosyltransferase group 2 family protein
EWF20_RS10585	ENOG4105DCI	Phosphohydrolase
EWF20_RS10765	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EWF20_RS10790	ENOG4108IUZ	ABC transporter
EWF20_RS10795	ENOG4105ERH	Fumarylacetoacetate hydrolase
EWF20_RS10940	ENOG4105CQ2	DNA polymerase
EWF20_RS10950	ENOG4105EYF	MMPL domain protein
EWF20_RS11005	ENOG4105PEJ	SchA CurD domain protein
EWF20_RS11010	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EWF20_RS11070	ENOG4107QR9	Iron-sulfur cluster binding protein
EWF20_RS11095	ENOG4105CTD	carboxy-peptidase
EWF20_RS11110	ENOG4108JJB	ABC transporter
EWF20_RS11205	ENOG4105C26	Dehydrogenase
EWF20_RS11245	ENOG4105VG1	fes assembly suf system protein
EWF20_RS11250	ENOG4105C7K	acetolactate synthase
EWF20_RS11265	ENOG4107RUY	(E1 component), alpha subunit
EWF20_RS11270	ENOG4105CPP	Dehydrogenase, E1 component
EWF20_RS11320	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EWF20_RS11330	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EWF20_RS11350	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EWF20_RS11390	ENOG4105CB5	ATP-dependent DNA helicase recG
EWF20_RS11420	ENOG4105EN6	Membrane
EWF20_RS11440	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
EWF20_RS11590	ENOG4105CJ1	ABC, transporter
EWF20_RS11610	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
EWF20_RS11615	ENOG4105C10	Electron transfer flavoprotein
EWF20_RS11635	ENOG4105KHC	sulfurtransferase
EWF20_RS11640	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EWF20_RS11650	ENOG4105DDK	oxidoreductase, beta subunit
EWF20_RS11655	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
EWF20_RS11670	ENOG4108IEG	Formate dehydrogenase Alpha subunit
EWF20_RS11685	ENOG4105C1G	acyl-Coa dehydrogenase
EWF20_RS11690	ENOG4105BZJ	Electron transfer flavoprotein
EWF20_RS11700	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
EWF20_RS11725	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EWF20_RS11745	ENOG4105C1G	acyl-Coa dehydrogenase
EWF20_RS11750	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EWF20_RS11760	ENOG4105BZN	citrate synthase
EWF20_RS11765	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EWF20_RS11770	ENOG4105CR4	methylisocitrate lyase
EWF20_RS11775	ENOG4105DXD	2-methylcitrate dehydratase
EWF20_RS11780	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
EWF20_RS11795	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
EWF20_RS11810	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
EWF20_RS11820	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
EWF20_RS11830	ENOG4105E4R	Precorrin-3B C17-methyltransferase
EWF20_RS11835	ENOG41081F0	Precorrin-8x methylmutase
EWF20_RS11840	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
EWF20_RS11850	ENOG4105D44	asparaginase
EWF20_RS11865	ENOG4105EHU	Circadian clock protein KaiC
EWF20_RS11895	ENOG4105WCA	Ferredoxin
EWF20_RS11905	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
EWF20_RS11910	ENOG4105DB1	molybdopterin oxidoreductase
EWF20_RS11940	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
EWF20_RS12020	ENOG4105FCD	Major Facilitator
EWF20_RS12060	ENOG4107RWR	Sodium hydrogen exchanger
EWF20_RS12080	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
EWF20_RS12135	ENOG4105EWK	phytoene
EWF20_RS12150	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
EWF20_RS12155	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
EWF20_RS12210	ENOG4105DF9	Lipoate-protein, ligase
EWF20_RS12235	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
EWF20_RS12245	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
EWF20_RS12250	ENOG4108UR0	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
EWF20_RS12255	ENOG4105DF9	Lipoate-protein, ligase
EWF20_RS12280	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
EWF20_RS12300	ENOG4105D5M	phosphate starvation-inducible protein
EWF20_RS12305	ENOG4105CGK	Exodeoxyribonuclease III
EWF20_RS12315	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
EWF20_RS12325	ENOG4105EYF	MMPL domain protein
EWF20_RS12355	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EWF20_RS12370	ENOG4105C5X	domain protein
EWF20_RS12375	ENOG4105C9Q	fumarate hydratase class II
EWF20_RS12405	ENOG4105CP7	Triose-phosphate isomerase
EWF20_RS12415	ENOG4105E0C	molybdate abc transporter
EWF20_RS12425	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
EWF20_RS12430	ENOG4105D1Z	hydroxypyruvate reductase
EWF20_RS12440	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
EWF20_RS12460	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EWF20_RS12475	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EWF20_RS12480	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
EWF20_RS12550	ENOG4105ESV	Glycosyl transferase, family 4
EWF20_RS12555	ENOG4105EAH	synthase
EWF20_RS12570	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
EWF20_RS12575	ENOG4105CE9	30S ribosomal protein S2
EWF20_RS12585	ENOG4108UJD	30S ribosomal protein S9
EWF20_RS12590	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
EWF20_RS12595	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
EWF20_RS12605	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
EWF20_RS12610	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
EWF20_RS12615	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EWF20_RS12635	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EWF20_RS12645	ENOG4105CQ2	DNA polymerase
EWF20_RS12680	ENOG4105CRK	lysyL-tRNA synthetase
EWF20_RS12710	ENOG4105DG4	malate L-lactate dehydrogenase
EWF20_RS12735	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EWF20_RS12740	ENOG4105DZS	Phenylacetate-CoA ligase
EWF20_RS12775	ENOG4106HB6	Alpha beta hydrolase
EWF20_RS12785	ENOG4108MYP	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
EWF20_RS12790	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EWF20_RS12795	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
EWF20_RS12820	ENOG4107WZZ	SMC domain protein
EWF20_RS12820	ENOG4107WZZ	SMC domain protein
EWF20_RS12895	ENOG4105K63	Thioredoxin
EWF20_RS12955	ENOG4105CAY	ferredoxin--nadp reductase
EWF20_RS12965	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
EWF20_RS12980	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EWF20_RS12985	ENOG4105C9B	Cysteine desulfurase
EWF20_RS12995	ENOG4108K7V	UPF0284 protein
EWF20_RS13010	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
EWF20_RS13015	ENOG4105J7I	hydrolase
EWF20_RS13030	ENOG4105K59	histidine triad (HIT) protein
EWF20_RS13040	ENOG4107VIJ	nudix hydrolase
EWF20_RS13055	ENOG4105Q33	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency
EWF20_RS13065	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
EWF20_RS13070	ENOG4105C4K	Nad synthetase
EWF20_RS13115	ENOG4108HMX	isocitrate dehydrogenase (NADP)
EWF20_RS13140	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
EWF20_RS13145	ENOG4105C01	Dihydroxy-acid dehydratase
EWF20_RS13155	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EWF20_RS13160	ENOG41088CC	tellurite resistance protein tehB
EWF20_RS13185	ENOG4108WBT	adenosyltransferase
EWF20_RS13190	ENOG4107Y9U	Membrane
EWF20_RS13195	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
EWF20_RS13205	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
EWF20_RS13215	ENOG4105CY0	Metallo-Beta-Lactamase
EWF20_RS13270	ENOG4105CBC	glutamate synthase
EWF20_RS13275	ENOG4105EYU	Glutamine amido-transferase
EWF20_RS13295	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EWF20_RS13300	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
EWF20_RS13360	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
EWF20_RS13370	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EWF20_RS13375	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EWF20_RS13385	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EWF20_RS13395	ENOG41082X4	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EWF20_RS13400	ENOG4105D65	subunit l
EWF20_RS13405	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EWF20_RS13410	ENOG4105CZA	synthase
EWF20_RS13415	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
EWF20_RS13455	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EWF20_RS13465	ENOG4108VCT	Sulfite exporter TauE/SafE
EWF20_RS13475	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
EWF20_RS13480	ENOG4105CHR	reductase
EWF20_RS13485	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
EWF20_RS13495	ENOG4105D82	Glutamate dehydrogenase
EWF20_RS13510	ENOG4105C8N	cysteinyl-tRNA synthetase
EWF20_RS13515	ENOG41086CI	Bifunctional phosphoglucose phosphomannose isomerase
EWF20_RS13545	ENOG4108S4H	thioesterase Superfamily protein
EWF20_RS13550	ENOG4105CPQ	Dehydrogenase
EWF20_RS13570	ENOG4105C1G	acyl-Coa dehydrogenase
EWF20_RS13640	ENOG4105D06	uba thif-type nad fad binding protein
EWF20_RS13645	ENOG4108HHA	Transketolase
EWF20_RS13650	ENOG4108IUS	Transketolase
EWF20_RS13655	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
EWF20_RS13660	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
EWF20_RS13665	ENOG4105D49	3-dehydroquinate synthase
EWF20_RS13670	ENOG4108237	shikimate dehydrogenase
EWF20_RS13675	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
EWF20_RS13680	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
EWF20_RS13685	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
EWF20_RS13705	ENOG4105DVT	helicase
EWF20_RS13725	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EWF20_RS13740	ENOG4105C7Z	Conserved Protein
EWF20_RS13745	ENOG4105CHR	reductase
EWF20_RS13760	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
EWF20_RS13780	ENOG4107QJE	Chromosome Partitioning Protein
EWF20_RS13790	ENOG4105CQB	FAD linked oxidase domain protein
EWF20_RS13805	ENOG4105DQU	oxidoreductase, subunit beta
EWF20_RS13810	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
EWF20_RS13835	ENOG4105DGU	Histone deacetylase
EWF20_RS13840	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
EWF20_RS13875	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
EWF20_RS13885	ENOG4107QRT	dEAD DEAH box helicase
EWF20_RS13890	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
EWF20_RS13925	ENOG4105DC7	peptidase M24
EWF20_RS13930	ENOG4105DGU	Histone deacetylase
EWF20_RS13945	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
EWF20_RS13950	ENOG4108RVA	ribokinase
EWF20_RS13955	ENOG4105DWF	phosphomethylpyrimidine kinase
EWF20_RS13975	ENOG4105CIF	Ornithine Cyclodeaminase
EWF20_RS13985	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
EWF20_RS14005	ENOG4105CPQ	Dehydrogenase
EWF20_RS14010	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
EWF20_RS14025	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EWF20_RS14030	ENOG4105D0M	Protease HtpX homolog
EWF20_RS14045	ENOG41061GT	Aldolase
EWF20_RS14070	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EWF20_RS14085	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
EWF20_RS14095	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
EWF20_RS14115	ENOG4105C54	Major Facilitator superfamily
EWF20_RS14135	ENOG4105MEW	serine threonine protein phosphatase
EWF20_RS14155	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EWF20_RS14205	ENOG4105D1H	recombination factor protein RarA
EWF20_RS14220	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
EWF20_RS14230	ENOG410834F	Transcriptional regulator
EWF20_RS14305	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EWF20_RS14320	ENOG4105DZC	cytosine deaminase
EWF20_RS14325	ENOG4105EUB	pirin domain protein
EWF20_RS14330	ENOG4105E50	uracil-dna glycosylase
EWF20_RS14355	ENOG4105C7K	acetolactate synthase
EWF20_RS14365	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
EWF20_RS14370	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EWF20_RS14390	ENOG4105CGU	Enoyl-CoA hydratase
EWF20_RS14395	ENOG4105CHU	acetyl-coa acetyltransferase
EWF20_RS14405	ENOG4105DZS	Phenylacetate-CoA ligase
EWF20_RS14420	ENOG4105JHE	Major Facilitator Superfamily
EWF20_RS14425	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EWF20_RS14450	ENOG4105C54	Major Facilitator superfamily
EWF20_RS14460	ENOG4105DQU	oxidoreductase, subunit beta
EWF20_RS14465	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
EWF20_RS14470	ENOG4105CIG	ABC transporter
EWF20_RS14485	ENOG4105D9P	serine threonine protein kinase
EWF20_RS14495	ENOG4105CEU	Arginine dihydrolase
EWF20_RS14500	ENOG4105D3R	alkyl hydroperoxide reductase
EWF20_RS14525	ENOG4108R96	Methyltransferase, YaeB family
EWF20_RS14555	ENOG4105D2S	major facilitator superfamily
EWF20_RS14590	ENOG4105C1J	atp-dependent rna helicase
EWF20_RS14615	ENOG4105FEU	K -dependent Na -Ca exchanger
EWF20_RS14620	ENOG4105VG5	Membrane
EWF20_RS14625	ENOG4105EM7	Selenocysteine-specific translation elongation factor
EWF20_RS14660	ENOG4107QTZ	amino acid
EWF20_RS14665	ENOG4105C26	Dehydrogenase
EWF20_RS14670	ENOG4105EDK	PfkB domain protein
EWF20_RS14675	ENOG4107SCR	N-acetylneuraminate lyase
EWF20_RS14680	ENOG4108594	Permease of the drug metabolite transporter
EWF20_RS14695	ENOG4105CEP	NADH dehydrogenase
EWF20_RS14710	ENOG4107ZTW	SNARE associated Golgi
EWF20_RS14730	ENOG4105D3W	isochorismatase
EWF20_RS14735	ENOG4105CJ1	ABC, transporter
EWF20_RS14750	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)