locus-tag	class	description
SCL_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SCL_RS00010	COG0592	DNA-directed DNA polymerase activity
SCL_RS00015	COG0187	DNA topoisomerase II activity
SCL_RS00020	COG2967	ApaG domain
SCL_RS00030	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SCL_RS00045	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SCL_RS00050	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SCL_RS00055	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SCL_RS00065	COG0037	tRNA processing
SCL_RS00095	COG1560	Kdo2-lipid A biosynthetic process
SCL_RS00100	COG1560	Kdo2-lipid A biosynthetic process
SCL_RS00115	COG2204	response regulator
SCL_RS00120	COG5000	phosphorelay sensor kinase activity
SCL_RS00130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SCL_RS00135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SCL_RS00140	COG0242	peptide deformylase activity
SCL_RS00150	COG0758	DNA mediated transformation
SCL_RS00155	COG2922	Belongs to the Smg family
SCL_RS00165	COG0730	response to heat
SCL_RS00180	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SCL_RS00195	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SCL_RS00200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SCL_RS00225	COG3245	cytochrome
SCL_RS00235	COG2960	long-chain fatty acid transporting porin activity
SCL_RS00250	COG0004	ammonium transporteR
SCL_RS00260	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SCL_RS00265	COG1166	arginine decarboxylase activity
SCL_RS00275	COG0018	arginyl-trna synthetase
SCL_RS00315	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SCL_RS00320	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SCL_RS00325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SCL_RS00330	COG0070	glutamate synthase
SCL_RS00330	COG0069	glutamate synthase activity
SCL_RS00330	COG0067	glutamate synthase
SCL_RS00340	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SCL_RS00355	COG5001	Diguanylate cyclase
SCL_RS00355	COG2203	Gaf domain
SCL_RS00355	COG4251	negative regulation of phosphorylation
SCL_RS00355	COG3706	GGDEF domain
SCL_RS00365	COG3347	Dehydrogenase
SCL_RS00365	COG1028	Short-chain dehydrogenase reductase Sdr
SCL_RS00380	COG1051	belongs to the nudix hydrolase family
SCL_RS00385	COG0446	pyridine nucleotide-disulphide oxidoreductase
SCL_RS00395	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SCL_RS00400	COG3001	Fructosamine kinase
SCL_RS00420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SCL_RS00440	COG0425	Belongs to the sulfur carrier protein TusA family
SCL_RS00450	COG2210	Belongs to the sulfur carrier protein TusA family
SCL_RS00470	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SCL_RS00495	COG1981	membrane
SCL_RS00505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SCL_RS00510	COG0697	spore germination
SCL_RS00520	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SCL_RS00525	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SCL_RS00530	COG0631	protein serine/threonine phosphatase activity
SCL_RS00540	COG1561	YicC-like family, N-terminal region
SCL_RS00550	COG1758	RNA polymerase activity
SCL_RS00555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SCL_RS00565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SCL_RS00575	COG3161	chorismate lyase activity
SCL_RS00580	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SCL_RS00585	COG0625	glutathione transferase activity
SCL_RS00595	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SCL_RS00615	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SCL_RS00620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SCL_RS00625	COG0339	signal peptide processing
SCL_RS00660	COG0672	)-iron permease
SCL_RS00675	COG1178	ABC-type Fe3 transport system permease component
SCL_RS00685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SCL_RS00695	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SCL_RS00700	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SCL_RS00705	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SCL_RS00710	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SCL_RS00725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SCL_RS00730	COG1331	Highly conserved protein containing a thioredoxin domain
SCL_RS00735	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SCL_RS00745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SCL_RS00755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SCL_RS00755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SCL_RS00760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SCL_RS00760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SCL_RS00765	COG0726	polysaccharide deacetylase
SCL_RS00780	COG1012	belongs to the aldehyde dehydrogenase family
SCL_RS00785	COG0741	lytic transglycosylase activity
SCL_RS00810	COG0617	tRNA 3'-terminal CCA addition
SCL_RS00820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SCL_RS00825	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SCL_RS00840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SCL_RS00845	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SCL_RS00850	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SCL_RS00855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SCL_RS00860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SCL_RS00865	COG1610	YqeY-like protein
SCL_RS00870	COG0358	DNA primase activity
SCL_RS00895	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
SCL_RS00925	COG2022	thiamine diphosphate biosynthetic process
SCL_RS00930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SCL_RS00935	COG2827	Endonuclease containing a URI domain
SCL_RS00965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SCL_RS00970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SCL_RS00980	COG0425	Belongs to the sulfur carrier protein TusA family
SCL_RS00995	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SCL_RS01000	COG0321	lipoyl(octanoyl) transferase activity
SCL_RS01020	COG2951	lytic endotransglycosylase activity
SCL_RS01025	COG0772	Belongs to the SEDS family
SCL_RS01030	COG0768	penicillin binding
SCL_RS01035	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
SCL_RS01040	COG1792	Involved in formation and maintenance of cell shape
SCL_RS01045	COG1077	Cell shape determining protein MreB Mrl
SCL_RS01050	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SCL_RS01055	COG0154	amidase activity
SCL_RS01060	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SCL_RS01065	COG3158	transport of potassium into the cell
SCL_RS01085	COG4191	Histidine kinase
SCL_RS01090	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
SCL_RS01095	COG2915	High frequency lysogenization protein hflD homolog
SCL_RS01130	COG0543	2 iron, 2 sulfur cluster binding
SCL_RS01130	COG0493	'glutamate synthase
SCL_RS01140	COG0315	cyclic pyranopterin monophosphate synthase activity
SCL_RS01145	COG0521	Mo-molybdopterin cofactor biosynthetic process
SCL_RS01150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SCL_RS01160	COG0303	'Molybdopterin
SCL_RS01165	COG0746	molybdenum cofactor guanylyltransferase activity
SCL_RS01170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SCL_RS01220	COG1612	heme a metabolic process
SCL_RS01235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SCL_RS01250	COG2703	oxygen carrier activity
SCL_RS01260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SCL_RS01265	COG2221	Nitrite and sulphite reductase 4Fe-4S
SCL_RS01270	COG2221	Nitrite and sulphite reductase 4Fe-4S
SCL_RS01335	COG0535	radical SAM domain protein
SCL_RS01355	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
SCL_RS01375	COG2716	regulation of RNA biosynthetic process
SCL_RS01395	COG0483	inositol monophosphate 1-phosphatase activity
SCL_RS01415	COG1131	(ABC) transporter
SCL_RS01420	COG3773	Cell wall hydrolase
SCL_RS01430	COG1538	Outer membrane efflux protein
SCL_RS01440	COG1028	Short-chain dehydrogenase reductase Sdr
SCL_RS01445	COG1252	NADH dehydrogenase
SCL_RS01455	COG0625	glutathione transferase activity
SCL_RS01465	COG0435	Glutathione S-transferase
SCL_RS01475	COG1741	Belongs to the pirin family
SCL_RS01480	COG0583	DNA-binding transcription factor activity
SCL_RS01485	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SCL_RS01485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SCL_RS01510	COG0826	peptidase U32
SCL_RS01515	COG0826	peptidase U32
SCL_RS01520	COG3154	lipid carrier protein
SCL_RS01525	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SCL_RS01540	COG1970	mechanosensitive ion channel activity
SCL_RS01545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SCL_RS01550	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SCL_RS01560	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
SCL_RS01570	COG0205	6-phosphofructokinase activity
SCL_RS01580	COG0563	adenylate kinase activity
SCL_RS01590	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
SCL_RS01600	COG5001	Diguanylate cyclase
SCL_RS01600	COG5002	protein histidine kinase activity
SCL_RS01620	COG1217	gtp-binding protein TYPA
SCL_RS01625	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SCL_RS01630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SCL_RS01635	COG0306	phosphate transporter
SCL_RS01645	COG0704	Plays a role in the regulation of phosphate uptake
SCL_RS01655	COG0581	inorganic phosphate transmembrane transporter activity
SCL_RS01660	COG0573	inorganic phosphate transmembrane transporter activity
SCL_RS01685	COG0798	PFAM Bile acid sodium symporter
SCL_RS01690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SCL_RS01700	COG2897	thiosulfate sulfurtransferase activity
SCL_RS01740	COG0640	Transcriptional regulator
SCL_RS01760	COG0745	RESPONSE REGULATOR receiver
SCL_RS01780	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SCL_RS01790	COG0693	protein deglycase activity
SCL_RS01795	COG0793	Belongs to the peptidase S41A family
SCL_RS01800	COG4942	peptidase
SCL_RS01805	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SCL_RS01810	COG0640	Transcriptional regulator
SCL_RS01815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SCL_RS01825	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
SCL_RS01830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SCL_RS01835	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SCL_RS01845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SCL_RS01850	COG1459	type II secretion system
SCL_RS01860	COG2165	general secretion pathway protein
SCL_RS01865	COG2165	general secretion pathway protein
SCL_RS01955	COG3409	Peptidoglycan-binding domain 1 protein
SCL_RS01955	COG3267	Type II secretory pathway component ExeA
SCL_RS01965	COG1040	competence protein
SCL_RS01970	COG0156	8-amino-7-oxononanoate synthase activity
SCL_RS01975	COG2267	carboxylic ester hydrolase activity
SCL_RS01980	COG2226	methyltransferase
SCL_RS01985	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SCL_RS01995	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SCL_RS02000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SCL_RS02005	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
SCL_RS02030	COG1612	heme a metabolic process
SCL_RS02035	COG0109	protoheme IX farnesyltransferase activity
SCL_RS02040	COG1999	signal sequence binding
SCL_RS02045	COG0450	alkyl hydroperoxide reductase
SCL_RS02065	COG0598	Magnesium transport protein CorA
SCL_RS02075	COG1366	Belongs to the anti-sigma-factor antagonist family
SCL_RS02085	COG3706	GGDEF domain
SCL_RS02090	COG0433	COG0433 Predicted ATPase
SCL_RS02095	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SCL_RS02105	COG3960	tartronate-semialdehyde synthase activity
SCL_RS02110	COG3622	Belongs to the hyi family
SCL_RS02115	COG2084	Dehydrogenase
SCL_RS02120	COG0247	lactate metabolic process
SCL_RS02155	COG0217	transcriptional regulatory protein
SCL_RS02160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SCL_RS02195	COG2226	methyltransferase
SCL_RS02235	COG2204	response regulator
SCL_RS02240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SCL_RS02250	COG0683	leucine binding
SCL_RS02255	COG1172	Belongs to the binding-protein-dependent transport system permease family
SCL_RS02260	COG1079	Belongs to the binding-protein-dependent transport system permease family
SCL_RS02275	COG1331	Highly conserved protein containing a thioredoxin domain
SCL_RS02285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SCL_RS02290	COG0425	Belongs to the sulfur carrier protein TusA family
SCL_RS02295	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SCL_RS02300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SCL_RS02315	COG2258	MOSC domain
SCL_RS02325	COG3706	GGDEF domain
SCL_RS02330	COG0756	dUTP diphosphatase activity
SCL_RS02335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SCL_RS02340	COG2003	Belongs to the UPF0758 family
SCL_RS02345	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SCL_RS02365	COG2816	NAD+ diphosphatase activity
SCL_RS02385	COG1595	DNA-templated transcription, initiation
SCL_RS02390	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SCL_RS02395	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SCL_RS02400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SCL_RS02405	COG0628	permease
SCL_RS02410	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SCL_RS02420	COG1393	Belongs to the ArsC family
SCL_RS02425	COG1295	ribonuclease BN
SCL_RS02425	COG1959	2 iron, 2 sulfur cluster binding
SCL_RS02435	COG1027	Aspartate ammonia-lyase
SCL_RS02440	COG0450	alkyl hydroperoxide reductase
SCL_RS02445	COG1254	Belongs to the acylphosphatase family
SCL_RS02455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SCL_RS02465	COG0442	prolyl-tRNA aminoacylation
SCL_RS02480	COG1940	carbohydrate kinase activity
SCL_RS02485	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SCL_RS02490	COG3577	Aspartyl protease
SCL_RS02500	COG0277	FAD linked oxidase domain protein
SCL_RS02505	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SCL_RS02510	COG2823	Periplasmic or secreted lipoprotein
SCL_RS02515	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SCL_RS02520	COG0792	nuclease activity
SCL_RS02550	COG1192	Involved in chromosome partitioning
SCL_RS02560	COG0243	molybdopterin cofactor binding
SCL_RS02565	COG0437	4 iron, 4 sulfur cluster binding
SCL_RS02570	COG3302	dmso reductase anchor subunit
SCL_RS02585	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
SCL_RS02590	COG4181	ATPase activity
SCL_RS02610	COG3409	Peptidoglycan-binding domain 1 protein
SCL_RS02610	COG3267	Type II secretory pathway component ExeA
SCL_RS02625	COG0563	adenylate kinase activity
SCL_RS02655	COG2001	Belongs to the MraZ family
SCL_RS02660	COG0275	rRNA processing
SCL_RS02680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SCL_RS02685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SCL_RS02690	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SCL_RS02695	COG0772	Belongs to the SEDS family
SCL_RS02700	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SCL_RS02705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SCL_RS02710	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SCL_RS02715	COG1181	Belongs to the D-alanine--D-alanine ligase family
SCL_RS02720	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SCL_RS02730	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SCL_RS02735	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SCL_RS02740	COG0739	heme binding
SCL_RS02745	COG0653	protein targeting
SCL_RS02750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SCL_RS02755	COG0237	dephospho-CoA kinase activity
SCL_RS02760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SCL_RS02825	COG0101	tRNA pseudouridine synthase activity
SCL_RS02835	COG0135	phosphoribosylanthranilate isomerase activity
SCL_RS02840	COG0133	tryptophan synthase activity
SCL_RS02845	COG0159	tryptophan synthase activity
SCL_RS02850	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SCL_RS02855	COG0285	dihydrofolate synthase activity
SCL_RS02885	COG2226	methyltransferase
SCL_RS02895	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SCL_RS02895	COG1918	ferrous iron import across plasma membrane
SCL_RS02910	COG3093	addiction module antidote protein HigA
SCL_RS02925	COG1047	Peptidyl-prolyl cis-trans
SCL_RS02980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SCL_RS02995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SCL_RS03005	COG1686	Belongs to the peptidase S11 family
SCL_RS03015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SCL_RS03015	COG0116	Belongs to the methyltransferase superfamily
SCL_RS03035	COG2884	Cell division ATP-binding protein ftsE
SCL_RS03040	COG0552	protein localization to endoplasmic reticulum
SCL_RS03055	COG0742	ribosomal rna small subunit methyltransferase
SCL_RS03060	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SCL_RS03065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SCL_RS03070	COG0405	Gamma-glutamyltransferase
SCL_RS03080	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SCL_RS03085	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SCL_RS03105	COG1131	(ABC) transporter
SCL_RS03115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SCL_RS03115	COG0543	2 iron, 2 sulfur cluster binding
SCL_RS03135	COG2959	enzyme of heme biosynthesis
SCL_RS03140	COG1587	Uroporphyrinogen-III synthase
SCL_RS03145	COG0181	hydroxymethylbilane synthase activity
SCL_RS03155	COG3275	phosphorelay sensor kinase activity
SCL_RS03165	COG0165	Argininosuccinate lyase
SCL_RS03170	COG3706	GGDEF domain
SCL_RS03220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SCL_RS03230	COG1965	Belongs to the frataxin family
SCL_RS03250	COG1832	CoA-binding protein
SCL_RS03255	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SCL_RS03265	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SCL_RS03285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SCL_RS03300	COG1278	Cold shock
SCL_RS03310	COG0004	ammonium transporteR
SCL_RS03330	COG1047	Peptidyl-prolyl cis-trans
SCL_RS03335	COG0432	Pfam Uncharacterised protein family UPF0047
SCL_RS03345	COG0543	2 iron, 2 sulfur cluster binding
SCL_RS03345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SCL_RS03350	COG0724	RNA recognition motif
SCL_RS03355	COG0513	Belongs to the DEAD box helicase family
SCL_RS03365	COG1515	deoxyribonuclease V activity
SCL_RS03380	COG2095	MarC family integral membrane protein
SCL_RS03390	COG3360	Dodecin
SCL_RS03405	COG0501	Belongs to the peptidase M48B family
SCL_RS03410	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SCL_RS03415	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
SCL_RS03420	COG0583	DNA-binding transcription factor activity
SCL_RS03430	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SCL_RS03435	COG0071	Belongs to the small heat shock protein (HSP20) family
SCL_RS03440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SCL_RS03445	COG1309	transcriptional regulator
SCL_RS03455	COG1704	LemA family
SCL_RS03465	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SCL_RS03470	COG2890	protein-(glutamine-N5) methyltransferase activity
SCL_RS03480	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SCL_RS03485	COG1966	Carbon starvation protein
SCL_RS03495	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
SCL_RS03500	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SCL_RS03510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SCL_RS03515	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SCL_RS03520	COG0193	aminoacyl-tRNA hydrolase activity
SCL_RS03525	COG0012	GTP binding
SCL_RS03535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SCL_RS03540	COG1702	phosphate starvation-inducible protein PhoH
SCL_RS03550	COG4535	Mg2 and Co2 transporter CorC
SCL_RS03555	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SCL_RS03570	COG0495	leucyl-tRNA aminoacylation
SCL_RS03580	COG1466	dna polymerase III delta subunit
SCL_RS03585	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SCL_RS03590	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SCL_RS03595	COG0799	negative regulation of ribosome biogenesis
SCL_RS03600	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SCL_RS03605	COG0424	maF-like protein
SCL_RS03625	COG0312	modulator of DNA gyrase
SCL_RS03630	COG0312	modulator of DNA gyrase
SCL_RS03655	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SCL_RS03660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SCL_RS03685	COG1355	regulation of microtubule-based process
SCL_RS03720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SCL_RS03745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SCL_RS03750	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
SCL_RS03760	COG0047	phosphoribosylformylglycinamidine synthase activity
SCL_RS03760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SCL_RS03785	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SCL_RS03790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SCL_RS03795	COG0363	glucosamine-6-phosphate deaminase activity
SCL_RS03805	COG0741	lytic transglycosylase activity
SCL_RS03820	COG3864	Putative metallopeptidase domain
SCL_RS03830	COG3158	transport of potassium into the cell
SCL_RS03840	COG5265	(ABC) transporter
SCL_RS03850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
SCL_RS03870	COG0488	(ABC) transporter
SCL_RS03875	COG3300	MHYT domain
SCL_RS03875	COG5001	Diguanylate cyclase
SCL_RS03880	COG0529	Catalyzes the synthesis of activated sulfate
SCL_RS03880	COG2046	Belongs to the sulfate adenylyltransferase family
SCL_RS03885	COG3842	ATPase activity
SCL_RS03890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SCL_RS03895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SCL_RS03910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SCL_RS03915	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
SCL_RS03920	COG0508	dehydrogenase complex catalyzes the overall conversion of
SCL_RS03925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SCL_RS03930	COG0137	argininosuccinate synthase activity
SCL_RS03935	COG3123	guanosine phosphorylase activity
SCL_RS03950	COG0463	Glycosyl transferase, family 2
SCL_RS03980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SCL_RS03985	COG2878	Part of a membrane complex involved in electron transport
SCL_RS04000	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCL_RS04000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SCL_RS04005	COG0489	protein tyrosine kinase activity
SCL_RS04010	COG0717	Belongs to the dCTP deaminase family
SCL_RS04050	COG3245	cytochrome
SCL_RS04055	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SCL_RS04065	COG0405	Gamma-glutamyltransferase
SCL_RS04070	COG0318	PFAM AMP-dependent synthetase and ligase
SCL_RS04085	COG0277	FAD linked oxidase domain protein
SCL_RS04090	COG0277	FAD linked oxidase domain protein
SCL_RS04100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SCL_RS04115	COG0247	lactate metabolic process
SCL_RS04120	COG1139	Iron-sulfur cluster binding protein
SCL_RS04125	COG1556	Lactate utilization protein
SCL_RS04135	COG2379	hydroxypyruvate reductase
SCL_RS04150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SCL_RS04155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SCL_RS04160	COG0215	cysteine-tRNA ligase activity
SCL_RS04165	COG0028	Belongs to the TPP enzyme family
SCL_RS04170	COG0440	acetolactate synthase activity
SCL_RS04175	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SCL_RS04180	COG0688	phosphatidylethanolamine metabolic process
SCL_RS04185	COG1183	phosphatidylcholine synthase activity
SCL_RS04190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SCL_RS04195	COG1573	uracil-dna glycosylase
SCL_RS04200	COG0456	acetyltransferase
SCL_RS04220	COG0494	nUDIX hydrolase
SCL_RS04255	COG1278	Cold shock
SCL_RS04260	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SCL_RS04280	COG0525	valine-tRNA ligase activity
SCL_RS04300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SCL_RS04330	COG1138	Cytochrome C-type biogenesis protein
SCL_RS04335	COG3088	subunit of a heme lyase
SCL_RS04345	COG0741	lytic transglycosylase activity
SCL_RS04375	COG0492	ferredoxin-NADP+ reductase activity
SCL_RS04380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SCL_RS04385	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
SCL_RS04405	COG4133	protoheme IX ABC transporter activity
SCL_RS04435	COG0463	Glycosyl transferase, family 2
SCL_RS04480	COG0142	geranyltranstransferase activity
SCL_RS04485	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SCL_RS04490	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SCL_RS04495	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SCL_RS04500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SCL_RS04505	COG0268	Binds directly to 16S ribosomal RNA
SCL_RS04510	COG0728	peptidoglycan biosynthetic process
SCL_RS04520	COG0196	riboflavin kinase activity
SCL_RS04525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SCL_RS04540	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SCL_RS04560	COG4966	pilus assembly protein PilW
SCL_RS04570	COG4970	Tfp pilus assembly protein FimT
SCL_RS04575	COG0735	belongs to the Fur family
SCL_RS04645	COG5002	protein histidine kinase activity
SCL_RS04645	COG5001	Diguanylate cyclase
SCL_RS04645	COG3447	MASE1 domain protein
SCL_RS04650	COG1858	cytochrome C peroxidase
SCL_RS04675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SCL_RS04700	COG3706	GGDEF domain
SCL_RS04705	COG0789	Transcriptional regulator
SCL_RS04725	COG2132	Multicopper oxidase
SCL_RS04795	COG0642	Histidine kinase
SCL_RS04835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SCL_RS04840	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SCL_RS04875	COG2217	Heavy metal translocating P-type atpase
SCL_RS04880	COG0058	SHG alpha-glucan phosphorylase activity
SCL_RS04885	COG0033	Phosphoglucomutase
SCL_RS04930	COG3023	N-Acetylmuramoyl-L-alanine amidase
SCL_RS04935	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SCL_RS04945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SCL_RS04950	COG2096	Adenosyltransferase
SCL_RS04960	COG4206	TonB-dependent receptor
SCL_RS04970	COG5001	Diguanylate cyclase
SCL_RS04975	COG1120	ATPase activity
SCL_RS04980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SCL_RS04995	COG0494	nUDIX hydrolase
SCL_RS05045	COG1070	Carbohydrate kinase
SCL_RS05050	COG1196	nuclear chromosome segregation
SCL_RS05055	COG3115	cell septum assembly
SCL_RS05060	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SCL_RS05065	COG1943	Transposase
SCL_RS05085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SCL_RS05095	COG2350	Protein conserved in bacteria
SCL_RS05100	COG2917	probably involved in intracellular septation
SCL_RS05110	COG0613	PHP domain protein
SCL_RS05115	COG0009	L-threonylcarbamoyladenylate synthase
SCL_RS05120	COG1994	Peptidase M50
SCL_RS05125	COG0180	Tryptophanyl-tRNA synthetase
SCL_RS05130	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SCL_RS05135	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SCL_RS05140	COG1187	pseudouridine synthase activity
SCL_RS05180	COG0429	hydrolase of the alpha beta-hydrolase fold
SCL_RS05190	COG3706	GGDEF domain
SCL_RS05200	COG1968	undecaprenyl-diphosphatase activity
SCL_RS05205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SCL_RS05210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SCL_RS05215	COG0436	Aminotransferase
SCL_RS05235	COG0720	synthase
SCL_RS05255	COG0617	tRNA 3'-terminal CCA addition
SCL_RS05260	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SCL_RS05265	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SCL_RS05270	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SCL_RS05275	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SCL_RS05280	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SCL_RS05295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SCL_RS05410	COG0582	viral genome integration into host DNA
SCL_RS05420	COG0837	glucose binding
SCL_RS05425	COG1543	Belongs to the glycosyl hydrolase 57 family
SCL_RS05455	COG0297	glycogen (starch) synthase activity
SCL_RS05460	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SCL_RS05485	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SCL_RS05490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SCL_RS05510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SCL_RS05515	COG0343	queuine tRNA-ribosyltransferase activity
SCL_RS05520	COG1862	Preprotein translocase
SCL_RS05525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SCL_RS05535	COG3707	response regulator
SCL_RS05540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SCL_RS05545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SCL_RS05550	COG1116	anion transmembrane transporter activity
SCL_RS05580	COG3706	GGDEF domain
SCL_RS05585	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SCL_RS05590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SCL_RS05595	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SCL_RS05595	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SCL_RS05610	COG0515	serine threonine protein kinase
SCL_RS05610	COG2815	serine threonine protein kinase
SCL_RS05620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SCL_RS05625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SCL_RS05635	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SCL_RS05660	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SCL_RS05665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SCL_RS05670	COG4536	flavin adenine dinucleotide binding
SCL_RS05675	COG0659	secondary active sulfate transmembrane transporter activity
SCL_RS05680	COG0659	secondary active sulfate transmembrane transporter activity
SCL_RS05685	COG0589	response to stress
SCL_RS05715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SCL_RS05725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SCL_RS05730	COG2146	nitrite reductase [NAD(P)H] activity
SCL_RS05735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SCL_RS05740	COG1028	Short-chain dehydrogenase reductase Sdr
SCL_RS05745	COG0222	ribosome binding
SCL_RS05755	COG1322	Protein conserved in bacteria
SCL_RS05765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SCL_RS05770	COG0402	S-adenosylhomocysteine deaminase activity
SCL_RS05780	COG0330	HflC and HflK could
SCL_RS05790	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SCL_RS05800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SCL_RS05805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SCL_RS05810	COG0077	Prephenate dehydratase
SCL_RS05810	COG1605	Chorismate mutase
SCL_RS05815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SCL_RS05820	COG0287	Prephenate dehydrogenase
SCL_RS05825	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SCL_RS05840	COG0776	regulation of translation
SCL_RS05850	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
SCL_RS05855	COG0284	orotidine-5'-phosphate decarboxylase activity
SCL_RS05860	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SCL_RS05860	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SCL_RS05865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SCL_RS05880	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SCL_RS05895	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SCL_RS05900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SCL_RS05905	COG1132	(ABC) transporter
SCL_RS05910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SCL_RS05915	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SCL_RS05920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SCL_RS05925	COG2089	acid synthase
SCL_RS05935	COG0189	ligase activity
SCL_RS05945	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SCL_RS05970	COG1028	Short-chain dehydrogenase reductase Sdr
SCL_RS05990	COG0107	imidazoleglycerol-phosphate synthase activity
SCL_RS05995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SCL_RS06020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SCL_RS06055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SCL_RS06080	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SCL_RS06085	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SCL_RS06095	COG0242	peptide deformylase activity
SCL_RS06100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SCL_RS06110	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SCL_RS06115	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SCL_RS06130	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SCL_RS06135	COG2840	Smr protein MutS2
SCL_RS06140	COG0492	ferredoxin-NADP+ reductase activity
SCL_RS06145	COG0686	Belongs to the AlaDH PNT family
SCL_RS06150	COG1674	ftsk spoiiie
SCL_RS06155	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
SCL_RS06160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SCL_RS06170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SCL_RS06175	COG1993	acr, cog1993
SCL_RS06180	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SCL_RS06200	COG1648	precorrin-2 dehydrogenase activity
SCL_RS06200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SCL_RS06205	COG2197	response regulator
SCL_RS06210	COG3850	Histidine kinase
SCL_RS06220	COG1797	cobyrinic acid a,c-diamide synthase activity
SCL_RS06255	COG2920	part of a sulfur-relay system
SCL_RS06260	COG2168	tRNA wobble position uridine thiolation
SCL_RS06265	COG2923	Belongs to the DsrF TusC family
SCL_RS06270	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
SCL_RS06275	COG2221	Nitrite and sulphite reductase 4Fe-4S
SCL_RS06280	COG2221	Nitrite and sulphite reductase 4Fe-4S
SCL_RS06315	COG2070	2-Nitropropane dioxygenase
SCL_RS06330	COG2862	Uncharacterized protein family, UPF0114
SCL_RS06335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SCL_RS06340	COG3128	pkhd-type hydroxylase
SCL_RS06355	COG0517	IMP dehydrogenase activity
SCL_RS06355	COG0516	GMP reductase activity
SCL_RS06390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SCL_RS06400	COG1923	regulation of RNA biosynthetic process
SCL_RS06405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SCL_RS06410	COG0330	HflC and HflK could
SCL_RS06415	COG0330	HflC and HflK could
SCL_RS06420	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
SCL_RS06425	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SCL_RS06430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SCL_RS06445	COG0557	exoribonuclease II activity
SCL_RS06450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SCL_RS06455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SCL_RS06465	COG0360	Binds together with S18 to 16S ribosomal RNA
SCL_RS06470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SCL_RS06475	COG0359	binds to the 23S rRNA
SCL_RS06485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SCL_RS06495	COG1716	ATPase activity
SCL_RS06500	COG0631	protein serine/threonine phosphatase activity
SCL_RS06505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SCL_RS06510	COG2171	N-acyltransferase activity
SCL_RS06515	COG0436	Aminotransferase
SCL_RS06520	COG5001	Diguanylate cyclase
SCL_RS06545	COG2226	methyltransferase
SCL_RS06555	COG2259	Doxx family
SCL_RS06565	COG0425	Belongs to the sulfur carrier protein TusA family
SCL_RS06570	COG0425	Belongs to the sulfur carrier protein TusA family
SCL_RS06590	COG2010	Cytochrome c
SCL_RS06605	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SCL_RS06655	COG0811	peptide transport
SCL_RS06660	COG0848	biopolymer transport protein
SCL_RS06665	COG1132	(ABC) transporter
SCL_RS06670	COG1663	tetraacyldisaccharide 4'-kinase activity
SCL_RS06675	COG1663	tetraacyldisaccharide 4'-kinase activity
SCL_RS06675	COG2835	tetraacyldisaccharide 4'-kinase activity
SCL_RS06680	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SCL_RS06685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SCL_RS06690	COG1530	ribonuclease E activity
SCL_RS06695	COG0564	pseudouridine synthase activity
SCL_RS06710	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SCL_RS06710	COG0616	signal peptide processing
SCL_RS06720	COG0511	ligase activity, forming carbon-carbon bonds
SCL_RS06720	COG5016	pyruvate
SCL_RS06725	COG0439	Biotin carboxylase
SCL_RS06730	COG1399	metal-binding, possibly nucleic acid-binding protein
SCL_RS06735	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SCL_RS06740	COG0416	fatty acid biosynthetic process
SCL_RS06745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SCL_RS06760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SCL_RS06765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SCL_RS06770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SCL_RS06775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SCL_RS06780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SCL_RS06785	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SCL_RS06800	COG0084	hydrolase, TatD family'
SCL_RS06805	COG0589	response to stress
SCL_RS06810	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SCL_RS06820	COG0438	transferase activity, transferring glycosyl groups
SCL_RS06825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SCL_RS06870	COG1671	Belongs to the UPF0178 family
SCL_RS06875	COG3588	fructose-bisphosphate aldolase
SCL_RS06895	COG1652	LysM domain
SCL_RS06910	COG1272	protein, Hemolysin III
SCL_RS06920	COG2223	nitrite transmembrane transporter activity
SCL_RS06925	COG0488	(ABC) transporter
SCL_RS06930	COG0513	Belongs to the DEAD box helicase family
SCL_RS06935	COG2900	Belongs to the SlyX family
SCL_RS06960	COG0488	(ABC) transporter
SCL_RS06995	COG2226	methyltransferase
SCL_RS07025	COG1716	ATPase activity
SCL_RS07040	COG2824	Alkylphosphonate utilization operon protein PhnA
SCL_RS07065	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SCL_RS07070	COG3177	Filamentation induced by cAMP protein fic
SCL_RS07095	COG3657	addiction module killer protein
SCL_RS07100	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
SCL_RS07125	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SCL_RS07130	COG2321	neutral zinc metallopeptidase
SCL_RS07175	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SCL_RS07180	COG0322	excinuclease ABC activity
SCL_RS07185	COG1573	uracil-dna glycosylase
SCL_RS07190	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SCL_RS07195	COG1472	Belongs to the glycosyl hydrolase 3 family
SCL_RS07205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SCL_RS07220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SCL_RS07245	COG2198	Histidine kinase
SCL_RS07245	COG2205	protein histidine kinase activity
SCL_RS07245	COG0784	Response regulator, receiver
SCL_RS07255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SCL_RS07260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SCL_RS07275	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
SCL_RS07280	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SCL_RS07285	COG0840	transmembrane signaling receptor activity
SCL_RS07295	COG0643	Histidine kinase
SCL_RS07295	COG2198	Histidine kinase
SCL_RS07300	COG0745	RESPONSE REGULATOR receiver
SCL_RS07315	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SCL_RS07325	COG0436	Aminotransferase
SCL_RS07350	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SCL_RS07365	COG0776	regulation of translation
SCL_RS07375	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SCL_RS07385	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SCL_RS07390	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SCL_RS07395	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SCL_RS07410	COG0436	Aminotransferase
SCL_RS07435	COG1024	Enoyl-CoA hydratase
SCL_RS07435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SCL_RS07440	COG0409	Hydrogenase expression formation protein
SCL_RS07445	COG0298	carbon dioxide binding
SCL_RS07450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SCL_RS07475	COG0736	holo-[acyl-carrier-protein] synthase activity
SCL_RS07480	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SCL_RS07485	COG1381	Involved in DNA repair and RecF pathway recombination
SCL_RS07490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SCL_RS07495	COG0571	ribonuclease III activity
SCL_RS07505	COG0681	Belongs to the peptidase S26 family
SCL_RS07510	COG0481	GTPase activity
SCL_RS07515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SCL_RS07520	COG3026	antisigma factor binding
SCL_RS07550	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SCL_RS07565	COG1053	succinate dehydrogenase
SCL_RS07570	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
SCL_RS07585	COG2855	membrane
SCL_RS07600	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
SCL_RS07605	COG0148	phosphopyruvate hydratase activity
SCL_RS07610	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SCL_RS07615	COG0504	CTP synthase activity
SCL_RS07620	COG0037	tRNA processing
SCL_RS07625	COG0825	malonyl-CoA metabolic process
SCL_RS07635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SCL_RS07765	COG0457	Tetratricopeptide repeat
SCL_RS07795	COG2226	methyltransferase
SCL_RS07835	COG2204	response regulator
SCL_RS07840	COG2198	Histidine kinase
SCL_RS07840	COG2205	protein histidine kinase activity
SCL_RS07840	COG0784	Response regulator, receiver
SCL_RS07850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SCL_RS07900	COG0367	asparagine synthase
SCL_RS07940	COG2046	Belongs to the sulfate adenylyltransferase family
SCL_RS07940	COG0529	Catalyzes the synthesis of activated sulfate
SCL_RS07965	COG2210	Belongs to the sulfur carrier protein TusA family
SCL_RS07970	COG3267	Type II secretory pathway component ExeA
SCL_RS07970	COG3409	Peptidoglycan-binding domain 1 protein
SCL_RS07995	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SCL_RS08000	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SCL_RS08005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SCL_RS08010	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SCL_RS08015	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
SCL_RS08030	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SCL_RS08035	COG0575	Belongs to the CDS family
SCL_RS08040	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SCL_RS08045	COG0233	cytoplasmic translational termination
SCL_RS08050	COG0528	UMP kinase activity
SCL_RS08055	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SCL_RS08060	COG0052	Belongs to the universal ribosomal protein uS2 family
SCL_RS08065	COG0024	Methionine aminopeptidase
SCL_RS08070	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SCL_RS08100	COG0860	N-Acetylmuramoyl-L-alanine amidase
SCL_RS08105	COG0802	atpase or kinase
SCL_RS08110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SCL_RS08110	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SCL_RS08125	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SCL_RS08130	COG0501	Belongs to the peptidase M48B family
SCL_RS08140	COG2154	pterin-4-alpha-carbinolamine dehydratase
SCL_RS08150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SCL_RS08155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SCL_RS08160	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SCL_RS08170	COG0419	ATPase involved in DNA repair
SCL_RS08190	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
SCL_RS08200	COG0519	Catalyzes the synthesis of GMP from XMP
SCL_RS08200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SCL_RS08215	COG1570	exodeoxyribonuclease VII activity
SCL_RS08220	COG0739	heme binding
SCL_RS08225	COG0515	serine threonine protein kinase
SCL_RS08230	COG1160	GTP binding
SCL_RS08240	COG2976	Protein conserved in bacteria
SCL_RS08245	COG0124	histidyl-tRNA synthetase
SCL_RS08250	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SCL_RS08255	COG1426	Protein conserved in bacteria
SCL_RS08265	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SCL_RS08270	COG2975	iron-sulfur cluster assembly
SCL_RS08285	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SCL_RS08290	COG0316	Belongs to the HesB IscA family
SCL_RS08295	COG0822	iron-sulfur transferase activity
SCL_RS08300	COG1104	cysteine desulfurase activity
SCL_RS08305	COG1104	cysteine desulfurase activity
SCL_RS08320	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
SCL_RS08340	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SCL_RS08370	COG5001	Diguanylate cyclase
SCL_RS08370	COG5002	protein histidine kinase activity
SCL_RS08380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SCL_RS08405	COG0438	transferase activity, transferring glycosyl groups
SCL_RS08415	COG1215	transferase activity, transferring glycosyl groups
SCL_RS08425	COG0438	transferase activity, transferring glycosyl groups
SCL_RS08430	COG0367	asparagine synthase
SCL_RS08435	COG0438	transferase activity, transferring glycosyl groups
SCL_RS08445	COG1216	Glycosyl transferase, family 2
SCL_RS08445	COG0438	transferase activity, transferring glycosyl groups
SCL_RS08455	COG2244	polysaccharide biosynthetic process
SCL_RS08465	COG1216	Glycosyl transferase, family 2
SCL_RS08480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SCL_RS08485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SCL_RS08490	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SCL_RS08505	COG3267	Type II secretory pathway component ExeA
SCL_RS08505	COG3409	Peptidoglycan-binding domain 1 protein
SCL_RS08515	COG0489	protein tyrosine kinase activity
SCL_RS08535	COG0484	heat shock protein binding
SCL_RS08540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SCL_RS08555	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
SCL_RS08560	COG0527	aspartate kinase activity
SCL_RS08565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SCL_RS08570	COG2137	regulation of response to DNA damage stimulus
SCL_RS08575	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SCL_RS08580	COG1546	Belongs to the CinA family
SCL_RS08585	COG0730	response to heat
SCL_RS08590	COG0531	amino acid
SCL_RS08595	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SCL_RS08600	COG1199	ATP-dependent helicase activity
SCL_RS08630	COG3852	Histidine kinase
SCL_RS08635	COG2204	response regulator
SCL_RS08645	COG5001	Diguanylate cyclase
SCL_RS08665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SCL_RS08695	COG3420	alginic acid biosynthetic process
SCL_RS08705	COG2823	Periplasmic or secreted lipoprotein
SCL_RS08745	COG0406	alpha-ribazole phosphatase activity
SCL_RS08750	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SCL_RS08755	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SCL_RS08810	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
SCL_RS08835	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SCL_RS08835	COG5297	Belongs to the glycosyl hydrolase family 6
SCL_RS08855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SCL_RS08870	COG2197	response regulator
SCL_RS08885	COG2172	sigma factor antagonist activity
SCL_RS08890	COG1366	Belongs to the anti-sigma-factor antagonist family
SCL_RS08895	COG1366	Belongs to the anti-sigma-factor antagonist family
SCL_RS08945	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SCL_RS08945	COG2755	lipolytic protein G-D-S-L family
SCL_RS08955	COG1215	transferase activity, transferring glycosyl groups
SCL_RS09000	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SCL_RS09020	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SCL_RS09030	COG5001	Diguanylate cyclase
SCL_RS09030	COG3300	MHYT domain
SCL_RS09040	COG3459	Glycosyltransferase 36 associated
SCL_RS09075	COG2823	Periplasmic or secreted lipoprotein
SCL_RS09095	COG1032	radical SAM domain protein
SCL_RS09155	COG0328	RNA-DNA hybrid ribonuclease activity
SCL_RS09160	COG2226	methyltransferase
SCL_RS09165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SCL_RS09170	COG1388	LysM domain
SCL_RS09170	COG0741	lytic transglycosylase activity
SCL_RS09175	COG4172	Belongs to the ABC transporter superfamily
SCL_RS09180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SCL_RS09185	COG0601	transmembrane transport
SCL_RS09200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SCL_RS09220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SCL_RS09225	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SCL_RS09230	COG0740	serine-type endopeptidase activity
SCL_RS09235	COG0544	peptidyl-prolyl cis-trans isomerase activity
SCL_RS09265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SCL_RS09270	COG0166	Belongs to the GPI family
SCL_RS09275	COG3228	Belongs to the MtfA family
SCL_RS09285	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SCL_RS09310	COG0473	3-isopropylmalate dehydrogenase activity
SCL_RS09315	COG0066	3-isopropylmalate dehydratase activity
SCL_RS09320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SCL_RS09335	COG2814	Major facilitator Superfamily
SCL_RS09345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SCL_RS09370	COG1181	Belongs to the D-alanine--D-alanine ligase family
SCL_RS09395	COG2020	methyltransferase activity
SCL_RS09410	COG0784	Response regulator, receiver
SCL_RS09410	COG4191	Histidine kinase
SCL_RS09425	COG1942	4-Oxalocrotonate Tautomerase
SCL_RS09485	COG5002	protein histidine kinase activity
SCL_RS09485	COG5001	Diguanylate cyclase
SCL_RS09485	COG3447	MASE1 domain protein
SCL_RS09490	COG1643	Atp-dependent helicase
SCL_RS09500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SCL_RS09505	COG0542	response to heat
SCL_RS09510	COG0204	Acyl-transferase
SCL_RS09510	COG0318	PFAM AMP-dependent synthetase and ligase
SCL_RS09520	COG0640	Transcriptional regulator
SCL_RS09525	COG0475	glutathione-regulated potassium exporter activity
SCL_RS09545	COG1073	alpha beta
SCL_RS09580	COG1496	oxidoreductase activity
SCL_RS09605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SCL_RS09610	COG0045	succinate-CoA ligase (ADP-forming) activity
SCL_RS09615	COG0577	efflux transmembrane transporter activity
SCL_RS09615	COG1136	(ABC) transporter
SCL_RS09645	COG1538	Outer membrane efflux protein
SCL_RS09655	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
SCL_RS09660	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
SCL_RS09670	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SCL_RS09675	COG0542	response to heat
SCL_RS09685	COG1278	Cold shock
SCL_RS09720	COG0791	NLP P60 protein
SCL_RS09730	COG3118	belongs to the thioredoxin family
SCL_RS09745	COG2226	methyltransferase
SCL_RS09755	COG5002	protein histidine kinase activity
SCL_RS09755	COG5001	Diguanylate cyclase
SCL_RS09770	COG3267	Type II secretory pathway component ExeA
SCL_RS09770	COG3409	Peptidoglycan-binding domain 1 protein
SCL_RS09800	COG0129	dihydroxy-acid dehydratase activity
SCL_RS09810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SCL_RS09810	COG0561	phosphatase activity
SCL_RS09815	COG0668	transmembrane transport
SCL_RS09825	COG0167	dihydroorotate dehydrogenase activity
SCL_RS09845	COG5001	Diguanylate cyclase
SCL_RS09845	COG1716	ATPase activity
SCL_RS09855	COG0673	inositol 2-dehydrogenase activity
SCL_RS09860	COG0300	oxidoreductase activity
SCL_RS09865	COG4251	negative regulation of phosphorylation
SCL_RS09870	COG0784	Response regulator, receiver
SCL_RS09880	COG5001	Diguanylate cyclase
SCL_RS09880	COG3300	MHYT domain
SCL_RS09890	COG2957	Belongs to the agmatine deiminase family
SCL_RS09905	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SCL_RS09905	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SCL_RS09910	COG0586	Pfam SNARE associated Golgi protein
SCL_RS09915	COG1278	Cold shock
SCL_RS09920	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SCL_RS09925	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SCL_RS09925	COG1605	Chorismate mutase
SCL_RS09935	COG0372	Belongs to the citrate synthase family
SCL_RS09940	COG2027	D-alanyl-D-alanine carboxypeptidase
SCL_RS09950	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SCL_RS09970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SCL_RS09975	COG0335	large ribosomal subunit rRNA binding
SCL_RS09985	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SCL_RS09990	COG0228	four-way junction DNA binding
SCL_RS09995	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SCL_RS10000	COG2853	Lipoprotein
SCL_RS10005	COG1881	PFAM PEBP family protein
SCL_RS10010	COG0243	molybdopterin cofactor binding
SCL_RS10015	COG1943	Transposase
SCL_RS10020	COG1185	polyribonucleotide nucleotidyltransferase activity
SCL_RS10025	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SCL_RS10035	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SCL_RS10040	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SCL_RS10045	COG0195	Participates in both transcription termination and antitermination
SCL_RS10045	COG2251	uridine kinase activity
SCL_RS10075	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SCL_RS10085	COG1007	ATP synthesis coupled electron transport
SCL_RS10100	COG0713	ATP synthesis coupled electron transport
SCL_RS10110	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SCL_RS10115	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SCL_RS10120	COG1034	ATP synthesis coupled electron transport
SCL_RS10130	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
SCL_RS10135	COG0649	NAD binding
SCL_RS10140	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SCL_RS10145	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SCL_RS10150	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SCL_RS10160	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SCL_RS10165	COG0149	triose-phosphate isomerase activity
SCL_RS10170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SCL_RS10175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SCL_RS10185	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
SCL_RS10195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SCL_RS10200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SCL_RS10205	COG0505	Belongs to the CarA family
SCL_RS10215	COG1285	pathogenesis
SCL_RS10225	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
SCL_RS10230	COG1704	LemA family
SCL_RS10235	COG0741	lytic transglycosylase activity
SCL_RS10240	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SCL_RS10270	COG0484	heat shock protein binding
SCL_RS10275	COG0443	Heat shock 70 kDa protein
SCL_RS10280	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SCL_RS10285	COG1420	regulation of RNA biosynthetic process
SCL_RS10290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SCL_RS10295	COG0497	DNA recombination
SCL_RS10300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SCL_RS10310	COG3746	phosphate-selective porin O and P
SCL_RS10325	COG0735	belongs to the Fur family
SCL_RS10330	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SCL_RS10335	COG2914	Belongs to the UPF0125 (RnfH) family
SCL_RS10345	COG0733	neurotransmitter:sodium symporter activity
SCL_RS10350	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SCL_RS10355	COG0842	Transport permease protein
SCL_RS10360	COG0842	Transport permease protein
SCL_RS10365	COG1131	(ABC) transporter
SCL_RS10370	COG1131	(ABC) transporter
SCL_RS10375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SCL_RS10405	COG1722	exodeoxyribonuclease VII activity
SCL_RS10410	COG0142	geranyltranstransferase activity
SCL_RS10415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SCL_RS10420	COG1469	GTP cyclohydrolase I activity
SCL_RS10425	COG5002	protein histidine kinase activity
SCL_RS10425	COG5001	Diguanylate cyclase
SCL_RS10480	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
SCL_RS10490	COG2391	methyltransferase activity
SCL_RS10505	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SCL_RS10510	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SCL_RS10515	COG5557	Pfam Polysulphide reductase, NrfD
SCL_RS10520	COG0437	4 iron, 4 sulfur cluster binding
SCL_RS10525	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SCL_RS10535	COG0375	protein maturation
SCL_RS10550	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SCL_RS10555	COG3300	MHYT domain
SCL_RS10555	COG5001	Diguanylate cyclase
SCL_RS10565	COG4206	TonB-dependent receptor
SCL_RS10580	COG5001	Diguanylate cyclase
SCL_RS10580	COG3300	MHYT domain
SCL_RS10585	COG2363	Small membrane protein
SCL_RS10605	COG1136	(ABC) transporter
SCL_RS10615	COG0577	efflux transmembrane transporter activity
SCL_RS10625	COG0789	Transcriptional regulator
SCL_RS10640	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SCL_RS10650	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SCL_RS10660	COG2969	positive regulation of protein catabolic process
SCL_RS10665	COG0625	glutathione transferase activity
SCL_RS10670	COG2857	Cytochrome c1
SCL_RS10675	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SCL_RS10680	COG0723	plastoquinol--plastocyanin reductase activity
SCL_RS10685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SCL_RS10695	COG0805	protein transport
SCL_RS10700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SCL_RS10705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SCL_RS10710	COG0140	phosphoribosyl-ATP diphosphatase activity
SCL_RS10715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SCL_RS10720	COG0107	imidazoleglycerol-phosphate synthase activity
SCL_RS10725	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SCL_RS10730	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SCL_RS10735	COG0131	Imidazoleglycerol-phosphate dehydratase
SCL_RS10740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SCL_RS10750	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SCL_RS10755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SCL_RS10760	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SCL_RS10770	COG0842	Transport permease protein
SCL_RS10775	COG1131	(ABC) transporter
SCL_RS10795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SCL_RS10800	COG1127	ABC transporter
SCL_RS10805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SCL_RS10820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SCL_RS10830	COG2176	DNA-directed DNA polymerase activity
SCL_RS10835	COG0517	IMP dehydrogenase activity
SCL_RS10835	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SCL_RS10840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SCL_RS10850	COG2249	NAD(P)H dehydrogenase (quinone) activity
SCL_RS10880	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
SCL_RS10885	COG1137	ATPase activity
SCL_RS10890	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SCL_RS10895	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SCL_RS10900	COG1660	Displays ATPase and GTPase activities
SCL_RS10910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SCL_RS10915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SCL_RS10925	COG2239	Acts as a magnesium transporter
SCL_RS10935	COG0583	DNA-binding transcription factor activity
SCL_RS10955	COG0425	Belongs to the sulfur carrier protein TusA family
SCL_RS10960	COG4783	chaperone-mediated protein folding
SCL_RS10980	COG3258	Cytochrome c
SCL_RS10985	COG0737	Belongs to the 5'-nucleotidase family
SCL_RS10990	COG3954	Phosphoribulokinase
SCL_RS11010	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SCL_RS11020	COG2391	methyltransferase activity
SCL_RS11025	COG0425	Belongs to the sulfur carrier protein TusA family
SCL_RS11030	COG2168	tRNA wobble position uridine thiolation
SCL_RS11035	COG2923	Belongs to the DsrF TusC family
SCL_RS11040	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
SCL_RS11045	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SCL_RS11050	COG0602	queuosine metabolic process
SCL_RS11055	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
SCL_RS11060	COG2885	chlorophyll binding
SCL_RS11065	COG0823	Involved in the tonB-independent uptake of proteins
SCL_RS11085	COG0824	Thioesterase
SCL_RS11090	COG2255	four-way junction helicase activity
SCL_RS11095	COG0632	four-way junction helicase activity
SCL_RS11100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SCL_RS11105	COG0217	transcriptional regulatory protein
SCL_RS11115	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SCL_RS11120	COG0494	nUDIX hydrolase
SCL_RS11125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SCL_RS11150	COG0537	adenosine 5'-monophosphoramidase activity
SCL_RS11155	COG0629	single-stranded DNA binding
SCL_RS11160	COG2814	Major facilitator Superfamily
SCL_RS11170	COG5002	protein histidine kinase activity
SCL_RS11170	COG5001	Diguanylate cyclase
SCL_RS11180	COG0203	ribosomal protein L17
SCL_RS11185	COG0202	RNA polymerase activity
SCL_RS11190	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SCL_RS11195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SCL_RS11200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SCL_RS11210	COG0201	protein transport
SCL_RS11215	COG0200	Binds to the 23S rRNA
SCL_RS11220	COG1841	ribosomal large subunit assembly
SCL_RS11225	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SCL_RS11230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SCL_RS11235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SCL_RS11240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SCL_RS11250	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SCL_RS11255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SCL_RS11260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SCL_RS11265	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SCL_RS11270	COG0255	Belongs to the universal ribosomal protein uL29 family
SCL_RS11275	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SCL_RS11280	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SCL_RS11285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SCL_RS11295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SCL_RS11300	COG0089	rRNA binding
SCL_RS11305	COG0088	Forms part of the polypeptide exit tunnel
SCL_RS11310	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SCL_RS11320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SCL_RS11325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SCL_RS11330	COG0049	tRNA binding
SCL_RS11335	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SCL_RS11340	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SCL_RS11345	COG0085	RNA polymerase activity
SCL_RS11350	COG0222	ribosome binding
SCL_RS11355	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SCL_RS11360	COG0081	regulation of translation
SCL_RS11375	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SCL_RS11385	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SCL_RS11405	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SCL_RS11415	COG0583	DNA-binding transcription factor activity
SCL_RS11430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SCL_RS11435	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SCL_RS11435	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SCL_RS11450	COG2084	Dehydrogenase
SCL_RS11455	COG0154	amidase activity
SCL_RS11475	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SCL_RS11485	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SCL_RS11495	COG1490	D-aminoacyl-tRNA deacylase activity
SCL_RS11535	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SCL_RS11540	COG0739	heme binding
SCL_RS11545	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SCL_RS11550	COG0316	Belongs to the HesB IscA family
SCL_RS11565	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SCL_RS11580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SCL_RS11585	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SCL_RS11590	COG3411	Ferredoxin
SCL_RS11595	COG0247	lactate metabolic process
SCL_RS11600	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
SCL_RS11615	COG0134	indole-3-glycerol-phosphate synthase activity
SCL_RS11620	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SCL_RS11625	COG2814	Major facilitator Superfamily
SCL_RS11630	COG0512	Glutamine amidotransferase of anthranilate synthase
SCL_RS11640	COG0546	phosphoglycolate phosphatase activity
SCL_RS11675	COG2217	Heavy metal translocating P-type atpase
SCL_RS11690	COG5001	Diguanylate cyclase
SCL_RS11700	COG2010	Cytochrome c
SCL_RS11705	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SCL_RS11710	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SCL_RS11715	COG4095	Psort location CytoplasmicMembrane, score
SCL_RS11720	COG0352	thiamine-phosphate diphosphorylase activity
SCL_RS11725	COG0418	dihydroorotase activity
SCL_RS11730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SCL_RS11735	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SCL_RS11745	COG3260	NADH ubiquinone oxidoreductase 20
SCL_RS11750	COG0649	NAD binding
SCL_RS11750	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SCL_RS11755	COG0651	ATP synthesis coupled electron transport
SCL_RS11765	COG0650	Formate hydrogenlyase subunit 4
SCL_RS11770	COG0651	ATP synthesis coupled electron transport
SCL_RS11785	COG4941	Belongs to the sigma-70 factor family
SCL_RS11790	COG3795	YCII-related domain
SCL_RS11800	COG3795	YCII-related domain
SCL_RS11825	COG3795	YCII-related domain
SCL_RS11830	COG1131	(ABC) transporter
SCL_RS11835	COG0842	Transport permease protein
SCL_RS11855	COG3813	Protein conserved in bacteria
SCL_RS11870	COG0288	reversible hydration of carbon dioxide
SCL_RS11875	COG3040	lipid binding
SCL_RS11880	COG1752	Esterase of the alpha-beta hydrolase superfamily
SCL_RS11885	COG0861	Integral membrane protein TerC family
SCL_RS11890	COG0191	fructose-bisphosphate aldolase activity
SCL_RS11905	COG4451	ribulose bisphosphate carboxylase, small
SCL_RS11910	COG1850	ribulose-bisphosphate carboxylase activity
SCL_RS11915	COG0583	DNA-binding transcription factor activity
SCL_RS11925	COG1368	sulfuric ester hydrolase activity
SCL_RS11950	COG1850	ribulose-bisphosphate carboxylase activity
SCL_RS11970	COG0191	fructose-bisphosphate aldolase activity
SCL_RS11975	COG0469	pyruvate kinase activity
SCL_RS11980	COG0126	phosphoglycerate kinase activity
SCL_RS11985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SCL_RS11990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SCL_RS12025	COG0784	Response regulator, receiver
SCL_RS12025	COG0643	Histidine kinase
SCL_RS12025	COG2198	Histidine kinase
SCL_RS12030	COG0840	transmembrane signaling receptor activity
SCL_RS12055	COG0189	ligase activity
SCL_RS12065	COG1678	Uncharacterized ACR, COG1678
SCL_RS12070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SCL_RS12075	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SCL_RS12080	COG0540	Belongs to the ATCase OTCase family
SCL_RS12110	COG1872	DUF167
SCL_RS12130	COG2223	nitrite transmembrane transporter activity
SCL_RS12135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SCL_RS12145	COG0708	Exodeoxyribonuclease III
SCL_RS12175	COG0314	molybdopterin synthase activity
SCL_RS12180	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SCL_RS12185	COG2046	Belongs to the sulfate adenylyltransferase family
SCL_RS12230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SCL_RS12235	COG2119	membrane
SCL_RS12265	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SCL_RS12275	COG5492	domain, Protein
SCL_RS12275	COG4932	domain protein
SCL_RS12340	COG3209	COG3209 Rhs family protein
SCL_RS12365	COG0348	domain, Protein
SCL_RS12370	COG2010	Cytochrome c
SCL_RS12385	COG3278	Belongs to the heme-copper respiratory oxidase family
SCL_RS12395	COG2217	Heavy metal translocating P-type atpase
SCL_RS12420	COG3706	GGDEF domain
SCL_RS12425	COG2815	serine threonine protein kinase
SCL_RS12425	COG0515	serine threonine protein kinase
SCL_RS12430	COG2048	Heterodisulfide reductase, subunit B
SCL_RS12440	COG1233	COG1233 Phytoene dehydrogenase and related
SCL_RS12445	COG1233	COG1233 Phytoene dehydrogenase and related
SCL_RS12465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SCL_RS12475	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SCL_RS12490	COG3178	'Phosphotransferase
SCL_RS12495	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
SCL_RS12500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SCL_RS12505	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SCL_RS12510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SCL_RS12525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SCL_RS12535	COG0751	glycine-tRNA ligase activity
SCL_RS12540	COG0752	glycyl-tRNA synthetase alpha subunit
SCL_RS12545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SCL_RS12550	COG0482	sulfurtransferase activity
SCL_RS12565	COG0174	glutamine synthetase
SCL_RS12570	COG3852	Histidine kinase
SCL_RS12585	COG2059	Chromate
SCL_RS12625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SCL_RS12630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SCL_RS12635	COG0006	proline dipeptidase activity
SCL_RS12650	COG3079	Belongs to the UPF0149 family
SCL_RS12670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SCL_RS12675	COG1692	metallophosphoesterase
SCL_RS12685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SCL_RS12690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SCL_RS12695	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SCL_RS12700	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SCL_RS12705	COG2204	response regulator
SCL_RS12710	COG4191	Histidine kinase
SCL_RS12730	COG3272	Protein of unknown function (DUF1722)
SCL_RS12770	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SCL_RS12775	COG1218	3'(2'),5'-bisphosphate nucleotidase
SCL_RS12780	COG0494	nUDIX hydrolase
SCL_RS12790	COG1011	Hydrolase
SCL_RS12815	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SCL_RS12850	COG2878	Part of a membrane complex involved in electron transport
SCL_RS12850	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
SCL_RS12855	COG1013	pyruvate-flavodoxin oxidoreductase activity
SCL_RS12855	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SCL_RS12855	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SCL_RS12855	COG0674	pyruvate-flavodoxin oxidoreductase activity
SCL_RS12860	COG4656	Part of a membrane complex involved in electron transport
SCL_RS12865	COG4658	electron transport chain
SCL_RS12870	COG4659	FMN binding
SCL_RS12875	COG4660	Part of a membrane complex involved in electron transport
SCL_RS12880	COG4657	Part of a membrane complex involved in electron transport
SCL_RS12895	COG0247	lactate metabolic process
SCL_RS12910	COG1950	PFAM Membrane protein of
SCL_RS12920	COG0589	response to stress
SCL_RS12935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SCL_RS12935	COG4651	solute:proton antiporter activity
SCL_RS12945	COG0530	calcium, potassium:sodium antiporter activity
SCL_RS12965	COG0564	pseudouridine synthase activity
SCL_RS12995	COG0519	Catalyzes the synthesis of GMP from XMP
SCL_RS13020	COG0702	epimerase
SCL_RS13035	COG2084	Dehydrogenase
SCL_RS13050	COG0583	DNA-binding transcription factor activity
SCL_RS13095	COG3108	Peptidase M15
SCL_RS13100	COG2989	Protein conserved in bacteria
SCL_RS13110	COG2814	Major facilitator Superfamily
SCL_RS13115	COG0514	ATP-dependent DNA helicase (RecQ)
SCL_RS13140	COG3209	COG3209 Rhs family protein
SCL_RS13155	COG1858	cytochrome C peroxidase
SCL_RS13210	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SCL_RS13215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SCL_RS13230	COG1519	Transferase
SCL_RS13235	COG0859	PFAM glycosyl transferase family 9
SCL_RS13270	COG0859	PFAM glycosyl transferase family 9
SCL_RS13285	COG2226	methyltransferase
SCL_RS13300	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SCL_RS13325	COG2226	methyltransferase
SCL_RS13345	COG0459	protein refolding
SCL_RS13350	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SCL_RS13355	COG3030	protein affecting phage T7 exclusion by the F plasmid
SCL_RS13360	COG1324	tolerance protein
SCL_RS13365	COG4232	protein-disulfide reductase activity
SCL_RS13370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SCL_RS13375	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SCL_RS13380	COG0511	ligase activity, forming carbon-carbon bonds
SCL_RS13385	COG0439	Biotin carboxylase
SCL_RS13390	COG2264	protein methyltransferase activity
SCL_RS13400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SCL_RS13410	COG0138	bifunctional purine biosynthesis protein purh
SCL_RS13425	COG0009	L-threonylcarbamoyladenylate synthase
SCL_RS13430	COG0408	coproporphyrinogen oxidase activity
SCL_RS13445	COG0330	HflC and HflK could
SCL_RS13465	COG3189	MarR family transcriptional regulator
SCL_RS13490	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SCL_RS13550	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SCL_RS13555	COG0254	rRNA binding
SCL_RS13560	COG1525	nuclease
SCL_RS13570	COG0281	malic enzyme
SCL_RS13575	COG0039	L-malate dehydrogenase activity
SCL_RS13580	COG2890	protein-(glutamine-N5) methyltransferase activity
SCL_RS13585	COG1022	Amp-dependent synthetase and ligase
SCL_RS13590	COG2067	long-chain fatty acid transport protein
SCL_RS13605	COG1960	acyl-CoA dehydrogenase activity
SCL_RS13610	COG1773	rubredoxin
SCL_RS13615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SCL_RS13630	COG0457	Tetratricopeptide repeat
SCL_RS13635	COG0457	Tetratricopeptide repeat
SCL_RS13645	COG0384	phenazine biosynthesis protein PhzF
SCL_RS13650	COG0352	thiamine-phosphate diphosphorylase activity
SCL_RS13655	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SCL_RS13675	COG1611	Belongs to the LOG family
SCL_RS13710	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
SCL_RS13720	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SCL_RS13730	COG0210	DNA helicase
SCL_RS13735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SCL_RS13740	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SCL_RS13750	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SCL_RS13755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SCL_RS13765	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SCL_RS13770	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SCL_RS13775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SCL_RS13785	COG0356	it plays a direct role in the translocation of protons across the membrane
SCL_RS13795	COG0516	GMP reductase activity
SCL_RS13795	COG0517	IMP dehydrogenase activity
SCL_RS13805	COG1475	DNA binding
SCL_RS13810	COG1192	Involved in chromosome partitioning
SCL_RS13815	COG0357	Ribosomal RNA small subunit methyltransferase G
SCL_RS13830	COG0445	tRNA wobble uridine modification
SCL_RS13835	COG0714	Associated with various cellular activities
SCL_RS13855	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SCL_RS13860	COG0706	membrane insertase activity
SCL_RS13865	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SCL_RS13870	COG0594	ribonuclease P activity
SCL_RS13875	COG0230	Belongs to the bacterial ribosomal protein bL34 family