locus-tag	class	description
SULKU_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SULKU_RS00010	COG0592	DNA-directed DNA polymerase activity
SULKU_RS00015	COG0187	DNA topoisomerase II activity
SULKU_RS00020	COG4943	cyclic-guanylate-specific phosphodiesterase activity
SULKU_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SULKU_RS00030	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SULKU_RS00040	COG0573	inorganic phosphate transmembrane transporter activity
SULKU_RS00050	COG2205	protein histidine kinase activity
SULKU_RS00060	COG0704	Plays a role in the regulation of phosphate uptake
SULKU_RS00090	COG2911	Protein conserved in bacteria
SULKU_RS00115	COG1492	cobalamin metabolic process
SULKU_RS00120	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SULKU_RS00125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SULKU_RS00135	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SULKU_RS00145	COG0778	Nitroreductase
SULKU_RS00150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SULKU_RS00155	COG1122	ATPase activity
SULKU_RS00160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SULKU_RS00175	COG0840	transmembrane signaling receptor activity
SULKU_RS00190	COG0575	Belongs to the CDS family
SULKU_RS00195	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SULKU_RS00205	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SULKU_RS00210	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SULKU_RS00225	COG0148	phosphopyruvate hydratase activity
SULKU_RS00230	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SULKU_RS00245	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SULKU_RS00255	COG0348	domain, Protein
SULKU_RS00260	COG2081	HI0933 family
SULKU_RS00265	COG1217	gtp-binding protein TYPA
SULKU_RS00275	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SULKU_RS00285	COG1749	Flagellar hook protein flgE
SULKU_RS00295	COG2814	Major facilitator Superfamily
SULKU_RS00300	COG0668	transmembrane transport
SULKU_RS00305	COG0778	Nitroreductase
SULKU_RS00320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SULKU_RS00340	COG1666	GTP binding
SULKU_RS00345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SULKU_RS00365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SULKU_RS00370	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SULKU_RS00375	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SULKU_RS00385	COG0358	DNA primase activity
SULKU_RS00390	COG0482	sulfurtransferase activity
SULKU_RS00470	COG0582	viral genome integration into host DNA
SULKU_RS00480	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SULKU_RS00500	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SULKU_RS00505	COG0237	dephospho-CoA kinase activity
SULKU_RS00510	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SULKU_RS00515	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SULKU_RS00520	COG0268	Binds directly to 16S ribosomal RNA
SULKU_RS00525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SULKU_RS00530	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SULKU_RS00545	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SULKU_RS00550	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SULKU_RS00565	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
SULKU_RS00570	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SULKU_RS00575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SULKU_RS00580	COG0107	imidazoleglycerol-phosphate synthase activity
SULKU_RS00590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SULKU_RS00600	COG0739	heme binding
SULKU_RS00615	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
SULKU_RS00630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SULKU_RS00650	COG0439	Biotin carboxylase
SULKU_RS00655	COG2076	Multidrug Resistance protein
SULKU_RS00695	COG0531	amino acid
SULKU_RS00700	COG2814	Major facilitator Superfamily
SULKU_RS00705	COG2022	thiamine diphosphate biosynthetic process
SULKU_RS00710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SULKU_RS00715	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SULKU_RS00715	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SULKU_RS00720	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SULKU_RS00720	COG0517	IMP dehydrogenase activity
SULKU_RS00725	COG1187	pseudouridine synthase activity
SULKU_RS00730	COG0432	Pfam Uncharacterised protein family UPF0047
SULKU_RS00735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SULKU_RS00740	COG1410	methionine synthase
SULKU_RS00740	COG0646	methionine synthase
SULKU_RS00745	COG2205	protein histidine kinase activity
SULKU_RS00745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SULKU_RS00765	COG4221	oxidoreductase activity
SULKU_RS00770	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
SULKU_RS00780	COG1086	Polysaccharide biosynthesis protein
SULKU_RS00785	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SULKU_RS00790	COG1083	cytidylyl-transferase
SULKU_RS00795	COG3980	spore coat polysaccharide biosynthesis protein
SULKU_RS00800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SULKU_RS00805	COG2089	acid synthase
SULKU_RS00820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SULKU_RS00825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SULKU_RS00835	COG0154	amidase activity
SULKU_RS00870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SULKU_RS00920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SULKU_RS00930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SULKU_RS00940	COG0492	ferredoxin-NADP+ reductase activity
SULKU_RS00960	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SULKU_RS00975	COG0051	transcription antitermination factor activity, RNA binding
SULKU_RS00980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SULKU_RS00985	COG0088	Forms part of the polypeptide exit tunnel
SULKU_RS00990	COG0089	rRNA binding
SULKU_RS00995	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SULKU_RS01000	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SULKU_RS01005	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SULKU_RS01010	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SULKU_RS01015	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SULKU_RS01020	COG0255	Belongs to the universal ribosomal protein uL29 family
SULKU_RS01025	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SULKU_RS01030	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SULKU_RS01035	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SULKU_RS01040	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SULKU_RS01045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SULKU_RS01050	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SULKU_RS01055	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SULKU_RS01060	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SULKU_RS01065	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SULKU_RS01070	COG0200	Binds to the 23S rRNA
SULKU_RS01075	COG0201	protein transport
SULKU_RS01080	COG0024	Methionine aminopeptidase
SULKU_RS01085	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SULKU_RS01095	COG3123	guanosine phosphorylase activity
SULKU_RS01115	COG3383	formate dehydrogenase (NAD+) activity
SULKU_RS01120	COG0792	nuclease activity
SULKU_RS01130	COG1858	cytochrome C peroxidase
SULKU_RS01135	COG3118	belongs to the thioredoxin family
SULKU_RS01140	COG0492	ferredoxin-NADP+ reductase activity
SULKU_RS01145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SULKU_RS01150	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SULKU_RS01155	COG1242	4 iron, 4 sulfur cluster binding
SULKU_RS01170	COG0140	phosphoribosyl-ATP diphosphatase activity
SULKU_RS01170	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SULKU_RS01175	COG0330	HflC and HflK could
SULKU_RS01190	COG1012	belongs to the aldehyde dehydrogenase family
SULKU_RS01195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SULKU_RS01205	COG0052	Belongs to the universal ribosomal protein uS2 family
SULKU_RS01210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SULKU_RS01215	COG1136	(ABC) transporter
SULKU_RS01220	COG1684	flagellar biosynthetic protein fliR
SULKU_RS01235	COG0194	GDP metabolic process
SULKU_RS01240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SULKU_RS01245	COG0018	arginyl-trna synthetase
SULKU_RS01250	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SULKU_RS01260	COG4753	response regulator
SULKU_RS01260	COG2207	Transcriptional regulator
SULKU_RS01275	COG0484	heat shock protein binding
SULKU_RS01290	COG0667	Aldo Keto reductase
SULKU_RS01305	COG0436	Aminotransferase
SULKU_RS01325	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SULKU_RS01335	COG0318	PFAM AMP-dependent synthetase and ligase
SULKU_RS01350	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULKU_RS01355	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULKU_RS01360	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULKU_RS01365	COG0649	NAD binding
SULKU_RS01385	COG1034	ATP synthesis coupled electron transport
SULKU_RS01390	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SULKU_RS01395	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULKU_RS01400	COG0839	Belongs to the complex I subunit 6 family
SULKU_RS01405	COG0713	ATP synthesis coupled electron transport
SULKU_RS01410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SULKU_RS01420	COG1007	ATP synthesis coupled electron transport
SULKU_RS01430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SULKU_RS01460	COG0799	negative regulation of ribosome biogenesis
SULKU_RS01465	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SULKU_RS01475	COG0126	phosphoglycerate kinase activity
SULKU_RS01480	COG0149	triose-phosphate isomerase activity
SULKU_RS01485	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SULKU_RS01505	COG0195	Participates in both transcription termination and antitermination
SULKU_RS01515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SULKU_RS01520	COG2121	Domain of unknown function (DUF374)
SULKU_RS01525	COG4974	Belongs to the 'phage' integrase family
SULKU_RS01545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SULKU_RS01550	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
SULKU_RS01555	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SULKU_RS01560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SULKU_RS01565	COG0037	tRNA processing
SULKU_RS01570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SULKU_RS01575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SULKU_RS01580	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
SULKU_RS01585	COG2081	HI0933 family
SULKU_RS01590	COG1252	NADH dehydrogenase
SULKU_RS01600	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SULKU_RS01605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SULKU_RS01610	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SULKU_RS01615	COG0612	Peptidase, M16
SULKU_RS01620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SULKU_RS01625	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SULKU_RS01655	COG0784	Response regulator, receiver
SULKU_RS01655	COG2205	protein histidine kinase activity
SULKU_RS01655	COG5002	protein histidine kinase activity
SULKU_RS01665	COG0840	transmembrane signaling receptor activity
SULKU_RS01670	COG0322	excinuclease ABC activity
SULKU_RS01675	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SULKU_RS01685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SULKU_RS01685	COG0519	Catalyzes the synthesis of GMP from XMP
SULKU_RS01705	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
SULKU_RS01715	COG1185	polyribonucleotide nucleotidyltransferase activity
SULKU_RS01720	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SULKU_RS01765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SULKU_RS01775	COG0390	transport system, permease component
SULKU_RS01780	COG0450	alkyl hydroperoxide reductase
SULKU_RS01785	COG1132	(ABC) transporter
SULKU_RS01790	COG0628	permease
SULKU_RS01805	COG1192	Involved in chromosome partitioning
SULKU_RS01815	COG2203	Gaf domain
SULKU_RS01815	COG2199	diguanylate cyclase activity
SULKU_RS01830	COG4771	TonB-dependent receptor
SULKU_RS01845	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SULKU_RS01850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SULKU_RS01855	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SULKU_RS01865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SULKU_RS01870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SULKU_RS01875	COG0825	malonyl-CoA metabolic process
SULKU_RS01885	COG0135	phosphoribosylanthranilate isomerase activity
SULKU_RS01890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SULKU_RS01905	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SULKU_RS01910	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SULKU_RS01915	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SULKU_RS01920	COG0481	GTPase activity
SULKU_RS01925	COG1040	competence protein
SULKU_RS01940	COG0471	metal ion transport
SULKU_RS01945	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SULKU_RS01950	COG0443	Heat shock 70 kDa protein
SULKU_RS01960	COG3093	addiction module antidote protein HigA
SULKU_RS01965	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SULKU_RS01970	COG4608	Belongs to the ABC transporter superfamily
SULKU_RS01975	COG0204	Acyl-transferase
SULKU_RS01985	COG0047	phosphoribosylformylglycinamidine synthase activity
SULKU_RS01990	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SULKU_RS01995	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SULKU_RS02000	COG0793	Belongs to the peptidase S41A family
SULKU_RS02010	COG0724	RNA recognition motif
SULKU_RS02015	COG5001	Diguanylate cyclase
SULKU_RS02015	COG3300	MHYT domain
SULKU_RS02020	COG0488	(ABC) transporter
SULKU_RS02040	COG2203	Gaf domain
SULKU_RS02040	COG3706	GGDEF domain
SULKU_RS02040	COG4251	negative regulation of phosphorylation
SULKU_RS02040	COG5001	Diguanylate cyclase
SULKU_RS02070	COG1230	cation diffusion facilitator family transporter
SULKU_RS02090	COG2199	diguanylate cyclase activity
SULKU_RS02090	COG3287	FIST C domain
SULKU_RS02090	COG2200	EAL domain
SULKU_RS02100	COG2199	diguanylate cyclase activity
SULKU_RS02100	COG2203	Gaf domain
SULKU_RS02145	COG0642	Histidine kinase
SULKU_RS02165	COG2304	oxidoreductase activity
SULKU_RS02175	COG0714	Associated with various cellular activities
SULKU_RS02200	COG0287	Prephenate dehydrogenase
SULKU_RS02205	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SULKU_RS02210	COG0248	Ppx GppA phosphatase
SULKU_RS02220	COG0642	Histidine kinase
SULKU_RS02225	COG0745	RESPONSE REGULATOR receiver
SULKU_RS02235	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SULKU_RS02245	COG0157	Belongs to the NadC ModD family
SULKU_RS02250	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SULKU_RS02260	COG0745	RESPONSE REGULATOR receiver
SULKU_RS02265	COG5002	protein histidine kinase activity
SULKU_RS02315	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SULKU_RS02325	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SULKU_RS02335	COG0083	homoserine kinase activity
SULKU_RS02340	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SULKU_RS02350	COG0779	Required for maturation of 30S ribosomal subunits
SULKU_RS02355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SULKU_RS02355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SULKU_RS02365	COG1570	exodeoxyribonuclease VII activity
SULKU_RS02375	COG2361	Protein of unknown function DUF86
SULKU_RS02380	COG0616	signal peptide processing
SULKU_RS02385	COG0402	S-adenosylhomocysteine deaminase activity
SULKU_RS02390	COG2201	protein-glutamate methylesterase activity
SULKU_RS02405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SULKU_RS02410	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SULKU_RS02415	COG1419	protein localization to endoplasmic reticulum
SULKU_RS02420	COG0455	bacterial-type flagellum organization
SULKU_RS02430	COG1191	sigma factor activity
SULKU_RS02435	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SULKU_RS02440	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SULKU_RS02440	COG1776	CheC inhibitor of MCP methylation
SULKU_RS02445	COG1611	Belongs to the LOG family
SULKU_RS02450	COG0482	sulfurtransferase activity
SULKU_RS02460	COG0288	reversible hydration of carbon dioxide
SULKU_RS02465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SULKU_RS02470	COG2860	membrane
SULKU_RS02475	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SULKU_RS02480	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SULKU_RS02495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SULKU_RS02505	COG1519	Transferase
SULKU_RS02510	COG0564	pseudouridine synthase activity
SULKU_RS02515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SULKU_RS02520	COG0228	four-way junction DNA binding
SULKU_RS02530	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SULKU_RS02535	COG0336	Belongs to the RNA methyltransferase TrmD family
SULKU_RS02540	COG0335	large ribosomal subunit rRNA binding
SULKU_RS02545	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SULKU_RS02565	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SULKU_RS02570	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
SULKU_RS02575	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SULKU_RS02580	COG0210	DNA helicase
SULKU_RS02585	COG0583	DNA-binding transcription factor activity
SULKU_RS02595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SULKU_RS02605	COG0439	Biotin carboxylase
SULKU_RS02610	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SULKU_RS02615	COG1862	Preprotein translocase
SULKU_RS02620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SULKU_RS02625	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SULKU_RS02630	COG0495	leucyl-tRNA aminoacylation
SULKU_RS02645	COG0285	dihydrofolate synthase activity
SULKU_RS02650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SULKU_RS02655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SULKU_RS02670	COG1451	nucleotide metabolic process
SULKU_RS02680	COG1215	transferase activity, transferring glycosyl groups
SULKU_RS02685	COG0726	polysaccharide deacetylase
SULKU_RS02685	COG1649	PFAM Uncharacterised BCR, COG1649
SULKU_RS02695	COG1692	metallophosphoesterase
SULKU_RS02725	COG4895	conserved protein (DUF2196)
SULKU_RS02735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SULKU_RS02745	COG2264	protein methyltransferase activity
SULKU_RS02755	COG1278	Cold shock
SULKU_RS02760	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SULKU_RS02765	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SULKU_RS02770	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SULKU_RS02775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SULKU_RS02780	COG3012	SEC-C Motif Domain Protein
SULKU_RS02785	COG1322	Protein conserved in bacteria
SULKU_RS02790	COG1183	phosphatidylcholine synthase activity
SULKU_RS02805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SULKU_RS02815	COG0745	RESPONSE REGULATOR receiver
SULKU_RS02820	COG0642	Histidine kinase
SULKU_RS02825	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SULKU_RS02830	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SULKU_RS02840	COG2200	EAL domain
SULKU_RS02845	COG3290	protein histidine kinase activity
SULKU_RS02845	COG0840	transmembrane signaling receptor activity
SULKU_RS02850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SULKU_RS02855	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SULKU_RS02860	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SULKU_RS02865	COG0835	chemotaxis
SULKU_RS02865	COG0784	Response regulator, receiver
SULKU_RS02870	COG2198	Histidine kinase
SULKU_RS02870	COG0784	Response regulator, receiver
SULKU_RS02870	COG0643	Histidine kinase
SULKU_RS02875	COG0835	chemotaxis
SULKU_RS02880	COG0006	proline dipeptidase activity
SULKU_RS02900	COG0542	response to heat
SULKU_RS02920	COG0706	membrane insertase activity
SULKU_RS02930	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SULKU_RS02935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SULKU_RS02945	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SULKU_RS02950	COG2861	carbohydrate metabolic process
SULKU_RS02965	COG0318	PFAM AMP-dependent synthetase and ligase
SULKU_RS03015	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SULKU_RS03020	COG0805	protein transport
SULKU_RS03025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SULKU_RS03030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SULKU_RS03040	COG0527	aspartate kinase activity
SULKU_RS03055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SULKU_RS03060	COG0475	glutathione-regulated potassium exporter activity
SULKU_RS03060	COG0569	domain protein
SULKU_RS03065	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SULKU_RS03070	COG1360	Flagellar Motor Protein
SULKU_RS03085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SULKU_RS03090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SULKU_RS03100	COG0776	regulation of translation
SULKU_RS03130	COG2226	methyltransferase
SULKU_RS03140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SULKU_RS03155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SULKU_RS03185	COG1566	PFAM secretion protein HlyD family protein
SULKU_RS03190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SULKU_RS03225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SULKU_RS03240	COG0243	molybdopterin cofactor binding
SULKU_RS03270	COG3706	GGDEF domain
SULKU_RS03275	COG0745	RESPONSE REGULATOR receiver
SULKU_RS03280	COG2205	protein histidine kinase activity
SULKU_RS03295	COG2046	Belongs to the sulfate adenylyltransferase family
SULKU_RS03305	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SULKU_RS03305	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SULKU_RS03310	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SULKU_RS03315	COG0489	protein tyrosine kinase activity
SULKU_RS03320	COG3706	GGDEF domain
SULKU_RS03330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SULKU_RS03335	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SULKU_RS03345	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SULKU_RS03350	COG0512	Glutamine amidotransferase of anthranilate synthase
SULKU_RS03360	COG0045	succinate-CoA ligase (ADP-forming) activity
SULKU_RS03400	COG0456	acetyltransferase
SULKU_RS03405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SULKU_RS03410	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SULKU_RS03415	COG0629	single-stranded DNA binding
SULKU_RS03420	COG0360	Binds together with S18 to 16S ribosomal RNA
SULKU_RS03430	COG0557	exoribonuclease II activity
SULKU_RS03445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SULKU_RS03455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SULKU_RS03460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SULKU_RS03495	COG3043	anaerobic respiration
SULKU_RS03500	COG0348	domain, Protein
SULKU_RS03505	COG0437	4 iron, 4 sulfur cluster binding
SULKU_RS03510	COG0243	molybdopterin cofactor binding
SULKU_RS03530	COG0742	ribosomal rna small subunit methyltransferase
SULKU_RS03535	COG1706	bacterial-type flagellum-dependent cell motility
SULKU_RS03540	COG3951	Flagellar rod assembly protein muramidase FlgJ
SULKU_RS03555	COG1256	bacterial-type flagellum assembly
SULKU_RS03555	COG4786	Flagellar basal body rod
SULKU_RS03560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SULKU_RS03580	COG3287	FIST C domain
SULKU_RS03580	COG2199	diguanylate cyclase activity
SULKU_RS03580	COG2200	EAL domain
SULKU_RS03595	COG0284	orotidine-5'-phosphate decarboxylase activity
SULKU_RS03605	COG5002	protein histidine kinase activity
SULKU_RS03605	COG5001	Diguanylate cyclase
SULKU_RS03615	COG0525	valine-tRNA ligase activity
SULKU_RS03620	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
SULKU_RS03630	COG1459	type II secretion system
SULKU_RS03635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SULKU_RS03695	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SULKU_RS03700	COG0359	binds to the 23S rRNA
SULKU_RS03710	COG0137	argininosuccinate synthase activity
SULKU_RS03745	COG0840	transmembrane signaling receptor activity
SULKU_RS03755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SULKU_RS03765	COG0251	oxidation-reduction process
SULKU_RS03780	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SULKU_RS03785	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SULKU_RS03790	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SULKU_RS03795	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SULKU_RS03800	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SULKU_RS03805	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SULKU_RS03805	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SULKU_RS03810	COG1192	Involved in chromosome partitioning
SULKU_RS03815	COG1475	DNA binding
SULKU_RS03830	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SULKU_RS03835	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SULKU_RS03840	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SULKU_RS03845	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SULKU_RS03850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SULKU_RS03855	COG0811	peptide transport
SULKU_RS03860	COG0848	biopolymer transport protein
SULKU_RS03870	COG0823	Involved in the tonB-independent uptake of proteins
SULKU_RS03885	COG1047	Peptidyl-prolyl cis-trans
SULKU_RS03890	COG2204	response regulator
SULKU_RS03895	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SULKU_RS03905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SULKU_RS03910	COG0037	tRNA processing
SULKU_RS03915	COG1194	a g-specific adenine glycosylase
SULKU_RS03940	COG1739	Uncharacterized protein family UPF0029
SULKU_RS03960	COG1704	LemA family
SULKU_RS04005	COG1058	Belongs to the CinA family
SULKU_RS04005	COG1546	Belongs to the CinA family
SULKU_RS04010	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SULKU_RS04015	COG0154	amidase activity
SULKU_RS04020	COG0516	GMP reductase activity
SULKU_RS04020	COG0517	IMP dehydrogenase activity
SULKU_RS04030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SULKU_RS04035	COG1722	exodeoxyribonuclease VII activity
SULKU_RS04045	COG4191	Histidine kinase
SULKU_RS04050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SULKU_RS04075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SULKU_RS04085	COG0726	polysaccharide deacetylase
SULKU_RS04095	COG0436	Aminotransferase
SULKU_RS04115	COG1193	negative regulation of DNA recombination
SULKU_RS04140	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SULKU_RS04150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SULKU_RS04155	COG1252	NADH dehydrogenase
SULKU_RS04160	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SULKU_RS04165	COG0196	riboflavin kinase activity
SULKU_RS04170	COG0356	it plays a direct role in the translocation of protons across the membrane
SULKU_RS04180	COG0352	thiamine-phosphate diphosphorylase activity
SULKU_RS04185	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SULKU_RS04190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SULKU_RS04200	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SULKU_RS04225	COG0676	glucose-6-phosphate 1-epimerase activity
SULKU_RS04230	COG0488	(ABC) transporter
SULKU_RS04240	COG1716	ATPase activity
SULKU_RS04240	COG5001	Diguanylate cyclase
SULKU_RS04260	COG1970	mechanosensitive ion channel activity
SULKU_RS04270	COG1136	(ABC) transporter
SULKU_RS04270	COG0577	efflux transmembrane transporter activity
SULKU_RS04275	COG1136	(ABC) transporter
SULKU_RS04275	COG0577	efflux transmembrane transporter activity
SULKU_RS04290	COG1592	Rubrerythrin
SULKU_RS04300	COG1528	Iron-storage protein
SULKU_RS04315	COG3128	pkhd-type hydroxylase
SULKU_RS04320	COG0811	peptide transport
SULKU_RS04325	COG0848	biopolymer transport protein
SULKU_RS04340	COG0501	Belongs to the peptidase M48B family
SULKU_RS04345	COG2890	protein-(glutamine-N5) methyltransferase activity
SULKU_RS04355	COG1127	ABC transporter
SULKU_RS04360	COG0484	heat shock protein binding
SULKU_RS04365	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SULKU_RS04370	COG0849	cell division
SULKU_RS04375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SULKU_RS04380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SULKU_RS04385	COG0275	rRNA processing
SULKU_RS04410	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SULKU_RS04415	COG0442	prolyl-tRNA aminoacylation
SULKU_RS04420	COG3030	protein affecting phage T7 exclusion by the F plasmid
SULKU_RS04430	COG0181	hydroxymethylbilane synthase activity
SULKU_RS04435	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SULKU_RS04445	COG0165	Argininosuccinate lyase
SULKU_RS04460	COG0537	adenosine 5'-monophosphoramidase activity
SULKU_RS04465	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SULKU_RS04470	COG0072	phenylalanine-tRNA ligase activity
SULKU_RS04470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SULKU_RS04475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SULKU_RS04480	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SULKU_RS04485	COG0539	negative regulation of cytoplasmic translation
SULKU_RS04485	COG1185	polyribonucleotide nucleotidyltransferase activity
SULKU_RS04495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SULKU_RS04530	COG0659	secondary active sulfate transmembrane transporter activity
SULKU_RS04535	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SULKU_RS04575	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
SULKU_RS04605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SULKU_RS04630	COG0745	RESPONSE REGULATOR receiver
SULKU_RS04645	COG1671	Belongs to the UPF0178 family
SULKU_RS04655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SULKU_RS04665	COG0587	DNA-directed DNA polymerase activity
SULKU_RS04685	COG1362	aminopeptidase activity
SULKU_RS04690	COG0642	Histidine kinase
SULKU_RS04700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SULKU_RS04705	COG0750	zinc metalloprotease
SULKU_RS04710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SULKU_RS04715	COG1028	Short-chain dehydrogenase reductase Sdr
SULKU_RS04720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SULKU_RS04730	COG0167	dihydroorotate dehydrogenase activity
SULKU_RS04740	COG1132	(ABC) transporter
SULKU_RS04745	COG0215	cysteine-tRNA ligase activity
SULKU_RS04750	COG0728	peptidoglycan biosynthetic process
SULKU_RS04760	COG0632	four-way junction helicase activity
SULKU_RS04765	COG1181	Belongs to the D-alanine--D-alanine ligase family
SULKU_RS04775	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SULKU_RS04800	COG1032	radical SAM domain protein
SULKU_RS04805	COG2200	EAL domain
SULKU_RS04805	COG2199	diguanylate cyclase activity
SULKU_RS04805	COG3287	FIST C domain
SULKU_RS04810	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SULKU_RS04815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SULKU_RS04820	COG0802	atpase or kinase
SULKU_RS04825	COG1137	ATPase activity
SULKU_RS04830	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SULKU_RS04845	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
SULKU_RS04855	COG0513	Belongs to the DEAD box helicase family
SULKU_RS04895	COG0835	chemotaxis
SULKU_RS04895	COG0784	Response regulator, receiver
SULKU_RS04910	COG2198	Histidine kinase
SULKU_RS04910	COG0643	Histidine kinase
SULKU_RS04920	COG0745	RESPONSE REGULATOR receiver
SULKU_RS04920	COG4566	intracellular signal transduction
SULKU_RS04935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SULKU_RS04940	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SULKU_RS04945	COG0343	queuine tRNA-ribosyltransferase activity
SULKU_RS04950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SULKU_RS04970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SULKU_RS04975	COG4786	Flagellar basal body rod
SULKU_RS04985	COG0840	transmembrane signaling receptor activity
SULKU_RS04985	COG3290	protein histidine kinase activity
SULKU_RS04990	COG0066	3-isopropylmalate dehydratase activity
SULKU_RS04995	COG0473	3-isopropylmalate dehydrogenase activity
SULKU_RS05010	COG0788	formyltetrahydrofolate deformylase activity
SULKU_RS05015	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SULKU_RS05035	COG2171	N-acyltransferase activity
SULKU_RS05045	COG0501	Belongs to the peptidase M48B family
SULKU_RS05055	COG0563	adenylate kinase activity
SULKU_RS05060	COG0563	adenylate kinase activity
SULKU_RS05065	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SULKU_RS05080	COG0667	Aldo Keto reductase
SULKU_RS05085	COG1053	succinate dehydrogenase
SULKU_RS05100	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SULKU_RS05110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SULKU_RS05115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULKU_RS05125	COG0521	Mo-molybdopterin cofactor biosynthetic process
SULKU_RS05145	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SULKU_RS05155	COG1331	Highly conserved protein containing a thioredoxin domain
SULKU_RS05160	COG4232	protein-disulfide reductase activity
SULKU_RS05185	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SULKU_RS05195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SULKU_RS05245	COG0745	RESPONSE REGULATOR receiver
SULKU_RS05260	COG0574	Belongs to the PEP-utilizing enzyme family
SULKU_RS05260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SULKU_RS05275	COG1013	pyruvate-flavodoxin oxidoreductase activity
SULKU_RS05280	COG1773	rubredoxin
SULKU_RS05290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SULKU_RS05305	COG1944	ATP diphosphatase activity
SULKU_RS05315	COG1648	precorrin-2 dehydrogenase activity
SULKU_RS05315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SULKU_RS05330	COG0175	sulfate reduction
SULKU_RS05335	COG0175	sulfate reduction
SULKU_RS05340	COG2895	sulfate adenylyltransferase (ATP) activity
SULKU_RS05345	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SULKU_RS05360	COG1959	2 iron, 2 sulfur cluster binding
SULKU_RS05370	COG0726	polysaccharide deacetylase
SULKU_RS05375	COG0842	Transport permease protein
SULKU_RS05380	COG1131	(ABC) transporter
SULKU_RS05395	COG2081	HI0933 family
SULKU_RS05400	COG0702	epimerase
SULKU_RS05425	COG3228	Belongs to the MtfA family
SULKU_RS05440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SULKU_RS05535	COG0484	heat shock protein binding
SULKU_RS05550	COG3706	GGDEF domain
SULKU_RS05550	COG2203	Gaf domain
SULKU_RS05550	COG4251	negative regulation of phosphorylation
SULKU_RS05550	COG5001	Diguanylate cyclase
SULKU_RS05575	COG0326	Molecular chaperone. Has ATPase activity
SULKU_RS05580	COG0101	tRNA pseudouridine synthase activity
SULKU_RS05590	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SULKU_RS05595	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SULKU_RS05600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SULKU_RS05605	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SULKU_RS05610	COG1338	Plays a role in the flagellum-specific transport system
SULKU_RS05615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SULKU_RS05630	COG5002	protein histidine kinase activity
SULKU_RS05640	COG2204	response regulator
SULKU_RS05660	COG2201	protein-glutamate methylesterase activity
SULKU_RS05665	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SULKU_RS05675	COG0067	glutamate synthase
SULKU_RS05675	COG0070	glutamate synthase
SULKU_RS05675	COG0069	glutamate synthase activity
SULKU_RS05680	COG0493	'glutamate synthase
SULKU_RS05685	COG0483	inositol monophosphate 1-phosphatase activity
SULKU_RS05690	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SULKU_RS05695	COG0352	thiamine-phosphate diphosphorylase activity
SULKU_RS05700	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SULKU_RS05715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SULKU_RS05725	COG1047	Peptidyl-prolyl cis-trans
SULKU_RS05730	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SULKU_RS05735	COG3842	ATPase activity
SULKU_RS05755	COG0500	methyltransferase
SULKU_RS05760	COG4774	siderophore transport
SULKU_RS05765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SULKU_RS05785	COG1120	ATPase activity
SULKU_RS05790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SULKU_RS05835	COG3585	molybdate ion transport
SULKU_RS05835	COG2005	Transcriptional regulator
SULKU_RS05840	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SULKU_RS05845	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SULKU_RS05860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SULKU_RS05865	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SULKU_RS05885	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SULKU_RS05905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SULKU_RS05920	COG4974	Belongs to the 'phage' integrase family
SULKU_RS05930	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SULKU_RS05935	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SULKU_RS05950	COG0166	Belongs to the GPI family
SULKU_RS05955	COG0840	transmembrane signaling receptor activity
SULKU_RS05960	COG0840	transmembrane signaling receptor activity
SULKU_RS05965	COG0513	Belongs to the DEAD box helicase family
SULKU_RS05970	COG1049	propionate catabolic process, 2-methylcitrate cycle
SULKU_RS05975	COG1196	nuclear chromosome segregation
SULKU_RS05975	COG1674	ftsk spoiiie
SULKU_RS06005	COG0708	Exodeoxyribonuclease III
SULKU_RS06020	COG3300	MHYT domain
SULKU_RS06020	COG5001	Diguanylate cyclase
SULKU_RS06035	COG2274	protein secretion by the type I secretion system
SULKU_RS06090	COG0419	ATPase involved in DNA repair
SULKU_RS06100	COG0840	transmembrane signaling receptor activity
SULKU_RS06130	COG2165	general secretion pathway protein
SULKU_RS06155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SULKU_RS06165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SULKU_RS06170	COG1459	type II secretion system
SULKU_RS06220	COG1045	serine acetyltransferase
SULKU_RS06225	COG1166	arginine decarboxylase activity
SULKU_RS06230	COG0124	histidyl-tRNA synthetase
SULKU_RS06235	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SULKU_RS06240	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SULKU_RS06245	COG0163	prenyltransferase activity
SULKU_RS06260	COG0659	secondary active sulfate transmembrane transporter activity
SULKU_RS06275	COG0842	Transport permease protein
SULKU_RS06275	COG1129	ABC transporter
SULKU_RS06285	COG0842	Transport permease protein
SULKU_RS06305	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SULKU_RS06325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SULKU_RS06335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SULKU_RS06340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SULKU_RS06360	COG0642	Histidine kinase
SULKU_RS06365	COG0745	RESPONSE REGULATOR receiver
SULKU_RS06375	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SULKU_RS06385	COG1449	Belongs to the glycosyl hydrolase 57 family
SULKU_RS06395	COG0297	glycogen (starch) synthase activity
SULKU_RS06405	COG0297	glycogen (starch) synthase activity
SULKU_RS06410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SULKU_RS06415	COG0166	Belongs to the GPI family
SULKU_RS06420	COG0058	SHG alpha-glucan phosphorylase activity
SULKU_RS06430	COG0126	phosphoglycerate kinase activity
SULKU_RS06435	COG0598	Magnesium transport protein CorA
SULKU_RS06440	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SULKU_RS06445	COG0280	phosphate acetyltransferase
SULKU_RS06445	COG0857	belongs to the CobB CobQ family
SULKU_RS06450	COG0513	Belongs to the DEAD box helicase family
SULKU_RS06455	COG2183	response to ionizing radiation
SULKU_RS06465	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SULKU_RS06475	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SULKU_RS06485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SULKU_RS06505	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SULKU_RS06525	COG0668	transmembrane transport
SULKU_RS06550	COG1433	Dinitrogenase iron-molybdenum cofactor
SULKU_RS06560	COG0716	FMN binding
SULKU_RS06575	COG0543	2 iron, 2 sulfur cluster binding
SULKU_RS06575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SULKU_RS06580	COG0633	Ferredoxin
SULKU_RS06585	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SULKU_RS06590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SULKU_RS06630	COG0686	Belongs to the AlaDH PNT family
SULKU_RS06640	COG0426	domain, Protein
SULKU_RS06650	COG1355	regulation of microtubule-based process
SULKU_RS06665	COG3287	FIST C domain
SULKU_RS06665	COG2199	diguanylate cyclase activity
SULKU_RS06665	COG2200	EAL domain
SULKU_RS06680	COG3706	GGDEF domain
SULKU_RS06690	COG2201	protein-glutamate methylesterase activity
SULKU_RS06790	COG3290	protein histidine kinase activity
SULKU_RS06790	COG0840	transmembrane signaling receptor activity
SULKU_RS06805	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SULKU_RS06855	COG0546	phosphoglycolate phosphatase activity
SULKU_RS06860	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SULKU_RS06880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SULKU_RS06880	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
SULKU_RS06900	COG1573	uracil-dna glycosylase
SULKU_RS06925	COG0824	Thioesterase
SULKU_RS06930	COG2223	nitrite transmembrane transporter activity
SULKU_RS06935	COG0515	serine threonine protein kinase
SULKU_RS06935	COG2815	serine threonine protein kinase
SULKU_RS06950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SULKU_RS06950	COG1116	anion transmembrane transporter activity
SULKU_RS06960	COG1116	anion transmembrane transporter activity
SULKU_RS06980	COG0243	molybdopterin cofactor binding
SULKU_RS06995	COG1643	Atp-dependent helicase
SULKU_RS07000	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SULKU_RS07005	COG0484	heat shock protein binding
SULKU_RS07015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SULKU_RS07015	COG1333	cytochrome c biogenesis protein
SULKU_RS07020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SULKU_RS07025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SULKU_RS07025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SULKU_RS07035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SULKU_RS07040	COG0730	response to heat
SULKU_RS07050	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SULKU_RS07070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SULKU_RS07075	COG0569	domain protein
SULKU_RS07085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SULKU_RS07090	COG0762	integral membrane protein
SULKU_RS07095	COG0741	lytic transglycosylase activity
SULKU_RS07105	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SULKU_RS07125	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SULKU_RS07125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SULKU_RS07140	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SULKU_RS07165	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SULKU_RS07170	COG0768	penicillin binding
SULKU_RS07180	COG1846	Transcriptional regulator
SULKU_RS07180	COG0456	acetyltransferase
SULKU_RS07185	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SULKU_RS07200	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SULKU_RS07205	COG0131	Imidazoleglycerol-phosphate dehydratase
SULKU_RS07210	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SULKU_RS07220	COG0084	hydrolase, TatD family'
SULKU_RS07225	COG0497	DNA recombination
SULKU_RS07230	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SULKU_RS07245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SULKU_RS07250	COG1832	CoA-binding protein
SULKU_RS07260	COG2199	diguanylate cyclase activity
SULKU_RS07260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SULKU_RS07265	COG0372	Belongs to the citrate synthase family
SULKU_RS07270	COG0579	oxidoreductase
SULKU_RS07335	COG0674	pyruvate-flavodoxin oxidoreductase activity
SULKU_RS07335	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SULKU_RS07350	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SULKU_RS07355	COG0045	succinate-CoA ligase (ADP-forming) activity
SULKU_RS07360	COG0114	fumarate hydratase activity
SULKU_RS07365	COG0039	L-malate dehydrogenase activity
SULKU_RS07375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SULKU_RS07385	COG0642	Histidine kinase
SULKU_RS07390	COG0745	RESPONSE REGULATOR receiver
SULKU_RS07445	COG0653	protein targeting
SULKU_RS07470	COG0436	Aminotransferase
SULKU_RS07485	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SULKU_RS07490	COG0440	acetolactate synthase activity
SULKU_RS07495	COG0028	Belongs to the TPP enzyme family
SULKU_RS07500	COG2201	protein-glutamate methylesterase activity
SULKU_RS07510	COG2198	Histidine kinase
SULKU_RS07510	COG0643	Histidine kinase
SULKU_RS07530	COG2199	diguanylate cyclase activity
SULKU_RS07540	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SULKU_RS07555	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SULKU_RS07600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SULKU_RS07605	COG0535	radical SAM domain protein
SULKU_RS07610	COG3287	FIST C domain
SULKU_RS07610	COG2199	diguanylate cyclase activity
SULKU_RS07610	COG2200	EAL domain
SULKU_RS07630	COG0740	serine-type endopeptidase activity
SULKU_RS07635	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SULKU_RS07640	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SULKU_RS07670	COG1741	Belongs to the pirin family
SULKU_RS07675	COG0659	secondary active sulfate transmembrane transporter activity
SULKU_RS07680	COG0697	spore germination
SULKU_RS07770	COG3706	GGDEF domain
SULKU_RS07860	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SULKU_RS07865	COG0681	Belongs to the peptidase S26 family
SULKU_RS07870	COG1994	Peptidase M50
SULKU_RS07875	COG0698	ribose 5-phosphate isomerase
SULKU_RS07885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SULKU_RS07890	COG0133	tryptophan synthase activity
SULKU_RS07895	COG0586	Pfam SNARE associated Golgi protein
SULKU_RS07900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SULKU_RS07905	COG0012	GTP binding
SULKU_RS07915	COG0688	phosphatidylethanolamine metabolic process
SULKU_RS07920	COG0585	pseudouridine synthase activity
SULKU_RS07925	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SULKU_RS07930	COG1053	succinate dehydrogenase
SULKU_RS07940	COG2048	Heterodisulfide reductase, subunit B
SULKU_RS07945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SULKU_RS07950	COG1663	tetraacyldisaccharide 4'-kinase activity
SULKU_RS07955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SULKU_RS07960	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SULKU_RS07965	COG2833	Protein of unknown function (DUF455)
SULKU_RS07970	COG2827	Endonuclease containing a URI domain
SULKU_RS07980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SULKU_RS07985	COG2050	protein possibly involved in aromatic compounds catabolism
SULKU_RS07985	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SULKU_RS07990	COG0500	methyltransferase
SULKU_RS08005	COG1418	mRNA catabolic process
SULKU_RS08015	COG0552	protein localization to endoplasmic reticulum
SULKU_RS08020	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SULKU_RS08035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SULKU_RS08040	COG1580	Controls the rotational direction of flagella during chemotaxis
SULKU_RS08045	COG0736	holo-[acyl-carrier-protein] synthase activity
SULKU_RS08055	COG3437	response regulator, receiver
SULKU_RS08055	COG0784	Response regulator, receiver
SULKU_RS08075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SULKU_RS08085	COG0835	chemotaxis
SULKU_RS08085	COG0784	Response regulator, receiver
SULKU_RS08100	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SULKU_RS08130	COG0415	Belongs to the DNA photolyase family
SULKU_RS08135	COG0840	transmembrane signaling receptor activity
SULKU_RS08150	COG0513	Belongs to the DEAD box helicase family
SULKU_RS08175	COG2199	diguanylate cyclase activity
SULKU_RS08175	COG2200	EAL domain
SULKU_RS08175	COG3287	FIST C domain
SULKU_RS08180	COG5002	protein histidine kinase activity
SULKU_RS08185	COG0745	RESPONSE REGULATOR receiver
SULKU_RS08190	COG2207	Transcriptional regulator
SULKU_RS08190	COG4753	response regulator
SULKU_RS08210	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SULKU_RS08215	COG2202	Pas domain
SULKU_RS08215	COG1366	Belongs to the anti-sigma-factor antagonist family
SULKU_RS08250	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SULKU_RS08255	COG0840	transmembrane signaling receptor activity
SULKU_RS08260	COG2983	Belongs to the UPF0260 family
SULKU_RS08315	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SULKU_RS08320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SULKU_RS08350	COG0835	chemotaxis
SULKU_RS08355	COG0386	Belongs to the glutathione peroxidase family
SULKU_RS08360	COG5001	Diguanylate cyclase
SULKU_RS08360	COG5002	protein histidine kinase activity
SULKU_RS08370	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
SULKU_RS08375	COG5002	protein histidine kinase activity
SULKU_RS08375	COG3850	Histidine kinase
SULKU_RS08395	COG0745	RESPONSE REGULATOR receiver
SULKU_RS08400	COG5001	Diguanylate cyclase
SULKU_RS08400	COG3447	MASE1 domain protein
SULKU_RS08400	COG5002	protein histidine kinase activity
SULKU_RS08560	COG1074	ATP-dependent DNA helicase activity
SULKU_RS08600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SULKU_RS08615	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SULKU_RS08625	COG0456	acetyltransferase
SULKU_RS08650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SULKU_RS08655	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SULKU_RS08680	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SULKU_RS08695	COG0772	Belongs to the SEDS family
SULKU_RS08700	COG0564	pseudouridine synthase activity
SULKU_RS08710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SULKU_RS08715	COG2884	Cell division ATP-binding protein ftsE
SULKU_RS08730	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SULKU_RS08735	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
SULKU_RS08745	COG5002	protein histidine kinase activity
SULKU_RS08745	COG5001	Diguanylate cyclase
SULKU_RS08760	COG0134	indole-3-glycerol-phosphate synthase activity
SULKU_RS08780	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SULKU_RS08805	COG2308	Evidence 4 Homologs of previously reported genes of
SULKU_RS08815	COG2308	Evidence 4 Homologs of previously reported genes of
SULKU_RS08825	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SULKU_RS08830	COG1959	2 iron, 2 sulfur cluster binding
SULKU_RS08835	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SULKU_RS08840	COG2404	hydrolase activity, acting on ester bonds
SULKU_RS08845	COG0488	(ABC) transporter
SULKU_RS08875	COG0564	pseudouridine synthase activity
SULKU_RS08895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SULKU_RS08910	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SULKU_RS08925	COG1902	pentaerythritol trinitrate reductase activity
SULKU_RS08930	COG2199	diguanylate cyclase activity
SULKU_RS08935	COG5002	protein histidine kinase activity
SULKU_RS08940	COG0745	RESPONSE REGULATOR receiver
SULKU_RS08950	COG0784	Response regulator, receiver
SULKU_RS08950	COG2205	protein histidine kinase activity
SULKU_RS08955	COG0784	Response regulator, receiver
SULKU_RS08955	COG3437	response regulator, receiver
SULKU_RS08960	COG1733	regulation of RNA biosynthetic process
SULKU_RS08965	COG2249	NAD(P)H dehydrogenase (quinone) activity
SULKU_RS08970	COG0778	Nitroreductase
SULKU_RS08975	COG1979	alcohol dehydrogenase
SULKU_RS08985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SULKU_RS09005	COG1126	abc transporter atp-binding protein
SULKU_RS09010	COG0519	Catalyzes the synthesis of GMP from XMP
SULKU_RS09015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SULKU_RS09055	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SULKU_RS09100	COG3290	protein histidine kinase activity
SULKU_RS09100	COG0840	transmembrane signaling receptor activity
SULKU_RS09110	COG1881	PFAM PEBP family protein
SULKU_RS09140	COG0217	transcriptional regulatory protein
SULKU_RS09155	COG4681	YaeQ
SULKU_RS09175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SULKU_RS09180	COG2176	DNA-directed DNA polymerase activity
SULKU_RS09190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SULKU_RS09195	COG3162	membrane
SULKU_RS09205	COG0745	RESPONSE REGULATOR receiver
SULKU_RS09210	COG5002	protein histidine kinase activity
SULKU_RS09215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SULKU_RS09220	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SULKU_RS09225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SULKU_RS09225	COG0475	glutathione-regulated potassium exporter activity
SULKU_RS09230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SULKU_RS09235	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SULKU_RS09240	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SULKU_RS09245	COG1077	Cell shape determining protein MreB Mrl
SULKU_RS09255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SULKU_RS09270	COG0754	glutathionylspermidine amidase activity
SULKU_RS09280	COG0860	N-Acetylmuramoyl-L-alanine amidase
SULKU_RS09290	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SULKU_RS09300	COG1758	RNA polymerase activity
SULKU_RS09305	COG0528	UMP kinase activity
SULKU_RS09315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SULKU_RS09330	COG1013	pyruvate-flavodoxin oxidoreductase activity
SULKU_RS09330	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SULKU_RS09330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SULKU_RS09330	COG0674	pyruvate-flavodoxin oxidoreductase activity
SULKU_RS09335	COG0339	signal peptide processing
SULKU_RS09350	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SULKU_RS09360	COG0484	heat shock protein binding
SULKU_RS09365	COG0138	bifunctional purine biosynthesis protein purh
SULKU_RS09390	COG1686	Belongs to the peptidase S11 family
SULKU_RS09400	COG3746	phosphate-selective porin O and P
SULKU_RS09405	COG0803	Belongs to the bacterial solute-binding protein 9 family
SULKU_RS09410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SULKU_RS09415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SULKU_RS09420	COG1127	ABC transporter
SULKU_RS09435	COG0205	6-phosphofructokinase activity
SULKU_RS09440	COG1090	epimerase
SULKU_RS09460	COG0560	Phosphoserine phosphatase
SULKU_RS09475	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SULKU_RS09485	COG1183	phosphatidylcholine synthase activity
SULKU_RS09495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SULKU_RS09500	COG2264	protein methyltransferase activity
SULKU_RS09505	COG0745	RESPONSE REGULATOR receiver
SULKU_RS09510	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SULKU_RS09515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SULKU_RS09520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SULKU_RS09525	COG0859	PFAM glycosyl transferase family 9
SULKU_RS09540	COG3787	Belongs to the UPF0306 family
SULKU_RS09545	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SULKU_RS09555	COG3290	protein histidine kinase activity
SULKU_RS09555	COG0840	transmembrane signaling receptor activity
SULKU_RS09560	COG0840	transmembrane signaling receptor activity
SULKU_RS09565	COG0840	transmembrane signaling receptor activity
SULKU_RS09570	COG0745	RESPONSE REGULATOR receiver
SULKU_RS09575	COG0745	RESPONSE REGULATOR receiver
SULKU_RS09590	COG0784	Response regulator, receiver
SULKU_RS09590	COG3437	response regulator, receiver
SULKU_RS09600	COG1496	oxidoreductase activity
SULKU_RS09605	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SULKU_RS09615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SULKU_RS09625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SULKU_RS09630	COG1605	Chorismate mutase
SULKU_RS09630	COG0077	Prephenate dehydratase
SULKU_RS09640	COG0019	diaminopimelate decarboxylase activity
SULKU_RS09650	COG0193	aminoacyl-tRNA hydrolase activity
SULKU_RS09655	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SULKU_RS09665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SULKU_RS09680	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
SULKU_RS09685	COG0542	response to heat
SULKU_RS09690	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SULKU_RS09695	COG2873	o-acetylhomoserine
SULKU_RS09700	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SULKU_RS09705	COG0540	Belongs to the ATCase OTCase family
SULKU_RS09710	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SULKU_RS09715	COG1555	photosystem II stabilization
SULKU_RS09715	COG1596	polysaccharide export
SULKU_RS09745	COG2824	Alkylphosphonate utilization operon protein PhnA
SULKU_RS09790	COG0745	RESPONSE REGULATOR receiver
SULKU_RS09795	COG0784	Response regulator, receiver
SULKU_RS09795	COG3437	response regulator, receiver
SULKU_RS09810	COG2201	protein-glutamate methylesterase activity
SULKU_RS09815	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
SULKU_RS09820	COG2205	protein histidine kinase activity
SULKU_RS09835	COG0643	Histidine kinase
SULKU_RS09835	COG2198	Histidine kinase
SULKU_RS09845	COG0840	transmembrane signaling receptor activity
SULKU_RS09850	COG0835	chemotaxis
SULKU_RS09855	COG0745	RESPONSE REGULATOR receiver
SULKU_RS09860	COG0784	Response regulator, receiver
SULKU_RS09860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SULKU_RS09860	COG2198	Histidine kinase
SULKU_RS09860	COG2205	protein histidine kinase activity
SULKU_RS09865	COG2815	serine threonine protein kinase
SULKU_RS09865	COG0515	serine threonine protein kinase
SULKU_RS09875	COG3706	GGDEF domain
SULKU_RS09940	COG0784	Response regulator, receiver
SULKU_RS09940	COG3437	response regulator, receiver
SULKU_RS09945	COG0840	transmembrane signaling receptor activity
SULKU_RS09950	COG0840	transmembrane signaling receptor activity
SULKU_RS09955	COG3706	GGDEF domain
SULKU_RS09965	COG0745	RESPONSE REGULATOR receiver
SULKU_RS09985	COG0159	tryptophan synthase activity
SULKU_RS09995	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SULKU_RS10000	COG2255	four-way junction helicase activity
SULKU_RS10005	COG0628	permease
SULKU_RS10015	COG0745	RESPONSE REGULATOR receiver
SULKU_RS10020	COG0642	Histidine kinase
SULKU_RS10025	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SULKU_RS10035	COG0748	coenzyme F420 binding
SULKU_RS10040	COG0247	lactate metabolic process
SULKU_RS10045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SULKU_RS10050	COG0745	RESPONSE REGULATOR receiver
SULKU_RS10060	COG0242	peptide deformylase activity
SULKU_RS10135	COG1271	oxidase subunit
SULKU_RS10140	COG1294	oxidase, subunit
SULKU_RS10150	COG2814	Major facilitator Superfamily
SULKU_RS10160	COG2203	Gaf domain
SULKU_RS10160	COG3706	GGDEF domain
SULKU_RS10160	COG5001	Diguanylate cyclase
SULKU_RS10160	COG4251	negative regulation of phosphorylation
SULKU_RS10185	COG0308	aminopeptidase N
SULKU_RS10190	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
SULKU_RS10195	COG0840	transmembrane signaling receptor activity
SULKU_RS10200	COG0840	transmembrane signaling receptor activity
SULKU_RS10215	COG0375	protein maturation
SULKU_RS10220	COG0309	Hydrogenase expression formation protein (HypE)
SULKU_RS10225	COG0409	Hydrogenase expression formation protein
SULKU_RS10230	COG0298	carbon dioxide binding
SULKU_RS10235	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SULKU_RS10240	COG1122	ATPase activity
SULKU_RS10255	COG0310	cobalt ion transport
SULKU_RS10260	COG2132	Multicopper oxidase
SULKU_RS10290	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SULKU_RS10295	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SULKU_RS10300	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SULKU_RS10310	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SULKU_RS10315	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SULKU_RS10320	COG3259	Nickel-dependent hydrogenase
SULKU_RS10325	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SULKU_RS10335	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SULKU_RS10340	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SULKU_RS10350	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
SULKU_RS10350	COG3261	NADH dehydrogenase
SULKU_RS10360	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SULKU_RS10365	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SULKU_RS10370	COG2111	Na H antiporter
SULKU_RS10370	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SULKU_RS10385	COG0745	RESPONSE REGULATOR receiver
SULKU_RS10390	COG2205	protein histidine kinase activity
SULKU_RS10400	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SULKU_RS10405	COG0459	protein refolding
SULKU_RS10425	COG0848	biopolymer transport protein
SULKU_RS10430	COG0811	peptide transport
SULKU_RS10435	COG0642	Histidine kinase
SULKU_RS10450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SULKU_RS10455	COG0004	ammonium transporteR
SULKU_RS10460	COG0347	Belongs to the P(II) protein family
SULKU_RS10465	COG0004	ammonium transporteR
SULKU_RS10490	COG2204	response regulator
SULKU_RS10495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SULKU_RS10505	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SULKU_RS10510	COG0731	radical SAM domain protein
SULKU_RS10550	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SULKU_RS10550	COG0662	Cupin 2, conserved barrel domain protein
SULKU_RS10565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SULKU_RS10660	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SULKU_RS10665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SULKU_RS10695	COG1088	dTDP-glucose 4,6-dehydratase activity
SULKU_RS10705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SULKU_RS10725	COG0438	transferase activity, transferring glycosyl groups
SULKU_RS10730	COG0463	Glycosyl transferase, family 2
SULKU_RS10735	COG0438	transferase activity, transferring glycosyl groups
SULKU_RS10760	COG1368	sulfuric ester hydrolase activity
SULKU_RS10770	COG0859	PFAM glycosyl transferase family 9
SULKU_RS10780	COG0859	PFAM glycosyl transferase family 9
SULKU_RS10790	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SULKU_RS10790	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SULKU_RS10795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SULKU_RS10810	COG2217	Heavy metal translocating P-type atpase
SULKU_RS10825	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SULKU_RS10840	COG3118	belongs to the thioredoxin family
SULKU_RS10845	COG1981	membrane
SULKU_RS10850	COG1160	GTP binding
SULKU_RS10855	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
SULKU_RS10860	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SULKU_RS10870	COG0105	UTP biosynthetic process
SULKU_RS10880	COG0416	fatty acid biosynthetic process
SULKU_RS10885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SULKU_RS10895	COG0513	Belongs to the DEAD box helicase family
SULKU_RS10910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SULKU_RS10915	COG0113	porphobilinogen synthase activity
SULKU_RS10920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SULKU_RS10925	COG0357	Ribosomal RNA small subunit methyltransferase G
SULKU_RS10940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SULKU_RS10945	COG2957	Belongs to the agmatine deiminase family
SULKU_RS10960	COG0739	heme binding
SULKU_RS10970	COG0277	FAD linked oxidase domain protein
SULKU_RS10975	COG1295	ribonuclease BN
SULKU_RS10985	COG0305	Participates in initiation and elongation during chromosome replication
SULKU_RS10990	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SULKU_RS10995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SULKU_RS11015	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SULKU_RS11020	COG0174	glutamine synthetase
SULKU_RS11025	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SULKU_RS11035	COG0826	peptidase U32
SULKU_RS11040	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SULKU_RS11060	COG0752	glycyl-tRNA synthetase alpha subunit
SULKU_RS11065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SULKU_RS11070	COG1858	cytochrome C peroxidase
SULKU_RS11085	COG1757	Na H antiporter
SULKU_RS11095	COG0745	RESPONSE REGULATOR receiver
SULKU_RS11100	COG0642	Histidine kinase
SULKU_RS11105	COG1686	Belongs to the peptidase S11 family
SULKU_RS11130	COG4191	Histidine kinase
SULKU_RS11135	COG1846	Transcriptional regulator
SULKU_RS11140	COG1741	Belongs to the pirin family
SULKU_RS11145	COG2353	YceI-like domain
SULKU_RS11150	COG3384	dioxygenase
SULKU_RS11160	COG0840	transmembrane signaling receptor activity
SULKU_RS11165	COG0556	nucleotide-excision repair
SULKU_RS11185	COG0444	Belongs to the ABC transporter superfamily
SULKU_RS11190	COG0156	8-amino-7-oxononanoate synthase activity
SULKU_RS11200	COG0424	maF-like protein
SULKU_RS11210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SULKU_RS11215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SULKU_RS11285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SULKU_RS11290	COG1459	type II secretion system
SULKU_RS11295	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SULKU_RS11300	COG0772	Belongs to the SEDS family
SULKU_RS11305	COG1815	bacterial-type flagellum-dependent cell motility
SULKU_RS11315	COG1677	Flagellar hook-basal body complex protein FliE
SULKU_RS11320	COG0768	penicillin binding
SULKU_RS11330	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SULKU_RS11335	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SULKU_RS11345	COG0179	Fumarylacetoacetate (FAA) hydrolase
SULKU_RS11395	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SULKU_RS11400	COG0049	tRNA binding
SULKU_RS11405	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SULKU_RS11410	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SULKU_RS11415	COG0085	RNA polymerase activity
SULKU_RS11420	COG0222	ribosome binding
SULKU_RS11425	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SULKU_RS11430	COG0081	regulation of translation
SULKU_RS11435	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SULKU_RS11440	COG0250	Participates in transcription elongation, termination and antitermination
SULKU_RS11455	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SULKU_RS11480	COG3022	response to hydroperoxide
SULKU_RS11485	COG0387	Pfam Sodium calcium exchanger
SULKU_RS11490	COG0598	Magnesium transport protein CorA
SULKU_RS11505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SULKU_RS11510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SULKU_RS11520	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SULKU_RS11525	COG3411	Ferredoxin
SULKU_RS11530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SULKU_RS11545	COG0203	ribosomal protein L17
SULKU_RS11550	COG0202	RNA polymerase activity
SULKU_RS11555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SULKU_RS11560	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SULKU_RS11565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SULKU_RS11570	COG0460	homoserine dehydrogenase
SULKU_RS11575	COG0436	Aminotransferase
SULKU_RS11590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SULKU_RS11595	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SULKU_RS11600	COG0254	rRNA binding
SULKU_RS11605	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SULKU_RS11615	COG0303	'Molybdopterin
SULKU_RS11625	COG0602	queuosine metabolic process
SULKU_RS11630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SULKU_RS11645	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SULKU_RS11650	COG0723	plastoquinol--plastocyanin reductase activity
SULKU_RS11660	COG0445	tRNA wobble uridine modification
SULKU_RS11700	COG1854	S-ribosylhomocysteine lyase activity
SULKU_RS11725	COG1013	pyruvate-flavodoxin oxidoreductase activity
SULKU_RS11730	COG0674	pyruvate-flavodoxin oxidoreductase activity
SULKU_RS11735	COG1144	Oxidoreductase
SULKU_RS11740	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SULKU_RS11745	COG0546	phosphoglycolate phosphatase activity
SULKU_RS11765	COG1368	sulfuric ester hydrolase activity
SULKU_RS11775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SULKU_RS11780	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SULKU_RS11825	COG3278	Belongs to the heme-copper respiratory oxidase family
SULKU_RS11830	COG0505	Belongs to the CarA family
SULKU_RS11850	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SULKU_RS11855	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SULKU_RS11860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SULKU_RS11865	COG1968	undecaprenyl-diphosphatase activity
SULKU_RS11870	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SULKU_RS11875	COG2814	Major facilitator Superfamily
SULKU_RS11895	COG0303	'Molybdopterin
SULKU_RS11900	COG0314	molybdopterin synthase activity
SULKU_RS11910	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SULKU_RS11915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SULKU_RS11930	COG0439	Biotin carboxylase
SULKU_RS11940	COG0717	Belongs to the dCTP deaminase family
SULKU_RS11960	COG0367	asparagine synthase
SULKU_RS11965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SULKU_RS11970	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SULKU_RS11975	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SULKU_RS11985	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SULKU_RS11995	COG0367	asparagine synthase
SULKU_RS12015	COG2089	acid synthase
SULKU_RS12035	COG3836	Belongs to the HpcH HpaI aldolase family
SULKU_RS12040	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SULKU_RS12065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SULKU_RS12080	COG1011	Hydrolase
SULKU_RS12090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SULKU_RS12110	COG1216	Glycosyl transferase, family 2
SULKU_RS12125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SULKU_RS12130	COG0110	maltose O-acetyltransferase activity
SULKU_RS12135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SULKU_RS12145	COG1086	Polysaccharide biosynthesis protein
SULKU_RS12160	COG0129	dihydroxy-acid dehydratase activity
SULKU_RS12235	COG0582	viral genome integration into host DNA
SULKU_RS12265	COG1879	ABC-type sugar transport system periplasmic component
SULKU_RS12285	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SULKU_RS12290	COG2353	YceI-like domain
SULKU_RS12335	COG2885	chlorophyll binding
SULKU_RS12360	COG5001	Diguanylate cyclase
SULKU_RS12370	COG0590	tRNA wobble adenosine to inosine editing
SULKU_RS12420	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
SULKU_RS12435	COG4771	TonB-dependent receptor
SULKU_RS12450	COG0348	domain, Protein
SULKU_RS12475	COG0784	Response regulator, receiver
SULKU_RS12475	COG3437	response regulator, receiver
SULKU_RS12485	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SULKU_RS12495	COG1408	metallophosphoesterase
SULKU_RS12500	COG0746	molybdenum cofactor guanylyltransferase activity
SULKU_RS12510	COG0315	cyclic pyranopterin monophosphate synthase activity
SULKU_RS12545	COG1140	nitrate reductase beta subunit
SULKU_RS12550	COG0243	molybdopterin cofactor binding
SULKU_RS12555	COG2897	thiosulfate sulfurtransferase activity
SULKU_RS12570	COG0489	protein tyrosine kinase activity
SULKU_RS12615	COG0670	Belongs to the BI1 family
SULKU_RS12620	COG0352	thiamine-phosphate diphosphorylase activity
SULKU_RS12640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SULKU_RS12645	COG1121	(ABC) transporter
SULKU_RS12660	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SULKU_RS12665	COG0233	cytoplasmic translational termination
SULKU_RS12670	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SULKU_RS12685	COG0504	CTP synthase activity
SULKU_RS12690	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SULKU_RS12690	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SULKU_RS12705	COG0328	RNA-DNA hybrid ribonuclease activity
SULKU_RS12710	COG0571	ribonuclease III activity
SULKU_RS12715	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SULKU_RS12720	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SULKU_RS12735	COG1157	protein secretion by the type III secretion system
SULKU_RS12740	COG0302	gtp cyclohydrolase
SULKU_RS12745	COG0544	peptidyl-prolyl cis-trans isomerase activity
SULKU_RS12750	COG0740	serine-type endopeptidase activity
SULKU_RS12760	COG0242	peptide deformylase activity
SULKU_RS12770	COG0606	chelatase, subunit chli
SULKU_RS12775	COG2755	lipolytic protein G-D-S-L family
SULKU_RS12780	COG2855	membrane
SULKU_RS12795	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SULKU_RS12820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SULKU_RS12830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SULKU_RS12835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SULKU_RS12840	COG0564	pseudouridine synthase activity
SULKU_RS12845	COG0564	pseudouridine synthase activity
SULKU_RS12860	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SULKU_RS12895	COG0187	DNA topoisomerase II activity
SULKU_RS13210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SULKU_RS13255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SULKU_RS13440	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SULKU_RS13740	COG1217	gtp-binding protein TYPA
SULKU_RS13780	COG1749	Flagellar hook protein flgE
SULKU_RS13865	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SULKU_RS13895	COG0187	DNA topoisomerase II activity
SULKU_RS14090	COG0148	phosphopyruvate hydratase activity
SULKU_RS14105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SULKU_RS14160	COG0840	transmembrane signaling receptor activity
SULKU_RS14160	COG3290	protein histidine kinase activity
SULKU_RS14165	COG2200	EAL domain
SULKU_RS14165	COG2199	diguanylate cyclase activity
SULKU_RS14165	COG3287	FIST C domain
SULKU_RS14185	COG2200	EAL domain
SULKU_RS14185	COG2199	diguanylate cyclase activity
SULKU_RS14185	COG3287	FIST C domain
SULKU_RS14190	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SULKU_RS14200	COG0642	Histidine kinase
SULKU_RS14215	COG0739	heme binding
SULKU_RS14225	COG3706	GGDEF domain
SULKU_RS14250	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SULKU_RS14255	COG0840	transmembrane signaling receptor activity
SULKU_RS14265	COG4191	Histidine kinase
SULKU_RS14270	COG2863	cytochrome
SULKU_RS14315	COG2199	diguanylate cyclase activity
SULKU_RS14315	COG2200	EAL domain
SULKU_RS14315	COG3287	FIST C domain
SULKU_RS14320	COG3706	GGDEF domain
SULKU_RS14325	COG0840	transmembrane signaling receptor activity
SULKU_RS14345	COG2885	chlorophyll binding
SULKU_RS14345	COG3047	cAMP biosynthetic process
SULKU_RS14365	COG3706	GGDEF domain
SULKU_RS14375	COG5001	Diguanylate cyclase
SULKU_RS14375	COG3300	MHYT domain
SULKU_RS14385	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SULKU_RS14395	COG0791	NLP P60 protein
SULKU_RS14415	COG3706	GGDEF domain
SULKU_RS14420	COG2200	EAL domain
SULKU_RS14420	COG3287	FIST C domain
SULKU_RS14420	COG2199	diguanylate cyclase activity
SULKU_RS14425	COG2203	Gaf domain
SULKU_RS14425	COG2199	diguanylate cyclase activity
SULKU_RS14430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SULKU_RS14440	COG3706	GGDEF domain
SULKU_RS14445	COG4753	response regulator
SULKU_RS14445	COG2207	Transcriptional regulator
SULKU_RS14465	COG2203	Gaf domain
SULKU_RS14465	COG3706	GGDEF domain
SULKU_RS14465	COG4251	negative regulation of phosphorylation
SULKU_RS14465	COG5001	Diguanylate cyclase
SULKU_RS14470	COG3706	GGDEF domain
SULKU_RS14475	COG0840	transmembrane signaling receptor activity
SULKU_RS14480	COG0745	RESPONSE REGULATOR receiver
SULKU_RS14490	COG0745	RESPONSE REGULATOR receiver
SULKU_RS14500	COG1401	restriction endodeoxyribonuclease activity
SULKU_RS14515	COG3437	response regulator, receiver
SULKU_RS14520	COG1858	cytochrome C peroxidase
SULKU_RS14535	COG0840	transmembrane signaling receptor activity
SULKU_RS14545	COG1342	Belongs to the UPF0251 family
SULKU_RS14580	COG4969	Belongs to the N-Me-Phe pilin family
SULKU_RS14585	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SULKU_RS14585	COG2199	diguanylate cyclase activity