locus-tag	class	description
SFSGTM_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
SFSGTM_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
SFSGTM_RS00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SFSGTM_RS00035	ENOG4107QMH	DNA methylase
SFSGTM_RS00125	ENOG4105ED9	Protein of unknown function (DUF455)
SFSGTM_RS00130	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
SFSGTM_RS00140	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
SFSGTM_RS00145	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
SFSGTM_RS00150	ENOG4108J6E	Pfam:Phage_integr_N
SFSGTM_RS00160	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
SFSGTM_RS00165	ENOG4105D1S	lipid A biosynthesis
SFSGTM_RS00175	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
SFSGTM_RS00180	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
SFSGTM_RS00185	ENOG4105SYT	Methylenetetrahydrofolate reductase
SFSGTM_RS00190	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
SFSGTM_RS00195	ENOG4105DZ0	fad dependent oxidoreductase
SFSGTM_RS00200	ENOG4107QRI	Phosphoketolase
SFSGTM_RS00205	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
SFSGTM_RS00210	ENOG4105DUM	transcriptional regulator, lysR family
SFSGTM_RS00215	ENOG4105BZU	Histidine kinase
SFSGTM_RS00225	ENOG4105BZU	Histidine kinase
SFSGTM_RS00230	ENOG4105WH1	Two component transcriptional regulator luxr family
SFSGTM_RS00235	ENOG4108IXY	short-chain dehydrogenase reductase
SFSGTM_RS00250	ENOG4105C75	arginyL-tRNA synthetase
SFSGTM_RS00260	ENOG41082RQ	UPF0102 protein
SFSGTM_RS00265	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
SFSGTM_RS00270	ENOG4105W4M	Transport-associated protein
SFSGTM_RS00275	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
SFSGTM_RS00280	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
SFSGTM_RS00295	ENOG41080IJ	Diacylglycerol kinase
SFSGTM_RS00305	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
SFSGTM_RS00310	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
SFSGTM_RS00315	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
SFSGTM_RS00345	ENOG4108IV0	ABC, transporter
SFSGTM_RS00350	ENOG4105C0Z	ABC transporter
SFSGTM_RS00355	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
SFSGTM_RS00360	ENOG4105C32	Amino acid ABC transporter (Permease)
SFSGTM_RS00365	ENOG4105CP9	extracellular ligand-binding receptor
SFSGTM_RS00370	ENOG4105W2Z	cytochrome C, class I
SFSGTM_RS00380	ENOG4105C01	Dihydroxy-acid dehydratase
SFSGTM_RS00385	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
SFSGTM_RS00390	ENOG4105C5Q	Transcriptional regulator
SFSGTM_RS00395	ENOG4108RAC	Rubrerythrin
SFSGTM_RS00400	ENOG4105VCQ	rubredoxin
SFSGTM_RS00405	ENOG4107QZF	nitrite reductase NADPH large subunit
SFSGTM_RS00410	ENOG4105BZU	Histidine kinase
SFSGTM_RS00420	ENOG4105D7N	magnesium and cobalt transport protein CorA
SFSGTM_RS00435	ENOG4105WH1	Two component transcriptional regulator luxr family
SFSGTM_RS00440	ENOG41080RH	Thioredoxin
SFSGTM_RS00465	ENOG4105D0M	Protease HtpX homolog
SFSGTM_RS00470	ENOG41063Z6	transcriptional regulator, lysR family
SFSGTM_RS00485	ENOG4105C59	p-type ATPase
SFSGTM_RS00505	ENOG4105DWV	Homoserine O-trans-acetylase
SFSGTM_RS00515	ENOG4105CY3	ABC transporter, permease
SFSGTM_RS00540	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
SFSGTM_RS00545	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
SFSGTM_RS00550	ENOG4108WZM	domain protein
SFSGTM_RS00555	ENOG4105C79	DNA protecting protein DprA
SFSGTM_RS00560	ENOG4108RPN	Protein smg homolog
SFSGTM_RS00625	ENOG4105VFB	Binds the 23S rRNA (By similarity)
SFSGTM_RS00635	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
SFSGTM_RS00640	ENOG4105D58	Diguanylate phosphodiesterase
SFSGTM_RS00645	ENOG4105XQ6	frataxin-like protein
SFSGTM_RS00655	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
SFSGTM_RS00665	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
SFSGTM_RS00670	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
SFSGTM_RS00675	ENOG4105C8V	SAICAR synthetase
SFSGTM_RS00680	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SFSGTM_RS00685	ENOG4105CUX	Signal transduction histidine kinase
SFSGTM_RS00705	ENOG4105E2X	shikimate dehydrogenase
SFSGTM_RS00710	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
SFSGTM_RS00735	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS00740	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS00765	ENOG4105CAF	HipA N-terminal domain protein
SFSGTM_RS00785	ENOG4105EZE	Cupin 4 family protein
SFSGTM_RS00790	ENOG4108YZY	peptidylprolyl cis-trans isomerase
SFSGTM_RS00795	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
SFSGTM_RS00800	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
SFSGTM_RS00835	ENOG4108Z0R	Transferase
SFSGTM_RS00840	ENOG4105DGW	oligopeptidase A
SFSGTM_RS00850	ENOG4105CGK	Exodeoxyribonuclease III
SFSGTM_RS00865	ENOG4105C0P	Mg chelatase subunit ChlI
SFSGTM_RS00870	ENOG4105W0Z	cytoplasmic protein
SFSGTM_RS00880	ENOG4108YZA	Nitrogen regulatory protein pii
SFSGTM_RS00885	ENOG4105BZU	Histidine kinase
SFSGTM_RS00890	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
SFSGTM_RS00910	ENOG4105C7K	acetolactate synthase
SFSGTM_RS00925	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SFSGTM_RS00955	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
SFSGTM_RS00970	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SFSGTM_RS00975	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SFSGTM_RS01040	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
SFSGTM_RS01120	ENOG4105D7V	transposase
SFSGTM_RS01125	ENOG4108RS6	transposase
SFSGTM_RS01155	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
SFSGTM_RS01160	ENOG41080ET	plasmid maintenance system killer protein
SFSGTM_RS01165	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
SFSGTM_RS01170	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
SFSGTM_RS01175	ENOG4105WJ3	XRE family Transcriptional regulator
SFSGTM_RS01255	ENOG4105D75	Capsular exopolysaccharide family
SFSGTM_RS01260	ENOG4105DAY	polysaccharide export protein
SFSGTM_RS01270	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
SFSGTM_RS01305	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
SFSGTM_RS01310	ENOG4105BZ1	(ABC) transporter
SFSGTM_RS01315	ENOG4107QN2	dihydrolipoyl dehydrogenase
SFSGTM_RS01320	ENOG4105CJW	magnesium transporter
SFSGTM_RS01325	ENOG4105EUP	HipA domain protein
SFSGTM_RS01330	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
SFSGTM_RS01335	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
SFSGTM_RS01350	ENOG4108Z4U	Ferredoxin
SFSGTM_RS01370	ENOG4108UB3	Thiamine monophosphate
SFSGTM_RS01385	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
SFSGTM_RS01395	ENOG4105HF0	Membrane
SFSGTM_RS01430	ENOG4105EGS	Mechanosensitive ion channel
SFSGTM_RS01435	ENOG4105N82	Endonuclease
SFSGTM_RS01455	ENOG4105CHH	sulfate transporter
SFSGTM_RS01460	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
SFSGTM_RS01465	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
SFSGTM_RS01470	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
SFSGTM_RS01490	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
SFSGTM_RS01500	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
SFSGTM_RS01520	ENOG4105ERG	peptidase m48, ste24p
SFSGTM_RS01550	ENOG4108MTB	glycosyl transferase family
SFSGTM_RS01555	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
SFSGTM_RS01560	ENOG4108IFG	nitrite reductase, (NAD(P)H)
SFSGTM_RS01580	ENOG4105BZU	Histidine kinase
SFSGTM_RS01585	ENOG4105I5W	Transporter
SFSGTM_RS01595	ENOG4105D7T	ABC transporter
SFSGTM_RS01610	ENOG4105BZU	Histidine kinase
SFSGTM_RS01615	ENOG4105C1J	atp-dependent rna helicase
SFSGTM_RS01620	ENOG4105EW9	transcriptional regulator AsnC family
SFSGTM_RS01625	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
SFSGTM_RS01630	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
SFSGTM_RS01635	ENOG4105KME	endoribonuclease L-psp
SFSGTM_RS01665	ENOG4105CYW	agmatinase
SFSGTM_RS01670	ENOG4105CJP	fad dependent oxidoreductase
SFSGTM_RS01680	ENOG4108Z86	Glutamine amidotransferase
SFSGTM_RS01685	ENOG4105CFQ	glutamine synthetase
SFSGTM_RS01690	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
SFSGTM_RS01695	ENOG4107RUE	extracellular solute-binding protein family 1
SFSGTM_RS01700	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SFSGTM_RS01705	ENOG4105F38	ABC transporter, permease
SFSGTM_RS01710	ENOG4105D38	putrescine abc transporter
SFSGTM_RS01720	ENOG4105C26	Dehydrogenase
SFSGTM_RS01725	ENOG4108JPW	Aminotransferase
SFSGTM_RS01735	ENOG4108V0P	LemA family
SFSGTM_RS01740	ENOG4105HA9	of methanol dehydrogenase type
SFSGTM_RS01770	ENOG4105KD7	acetyltransferase
SFSGTM_RS01780	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SFSGTM_RS01785	ENOG4105DHQ	Histidine kinase
SFSGTM_RS01815	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS01820	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS01835	ENOG4105C26	Dehydrogenase
SFSGTM_RS01840	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
SFSGTM_RS01845	ENOG4107VRI	Transcriptional regulator
SFSGTM_RS01850	ENOG4105FDP	GntR family transcriptional regulator
SFSGTM_RS01860	ENOG41068K7	succinate dehydrogenase, hydrophobic membrane anchor protein
SFSGTM_RS01870	ENOG4105E33	succinate dehydrogenase
SFSGTM_RS01875	ENOG410681N	tpr repeat protein
SFSGTM_RS01880	ENOG4105D6Z	AFG1 family ATPase
SFSGTM_RS01900	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
SFSGTM_RS01905	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
SFSGTM_RS01910	ENOG4105QAS	Iron-sulfur cluster assembly accessory protein
SFSGTM_RS01955	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SFSGTM_RS01970	ENOG4105WJZ	Glutathione S-transferase, C-terminal domain
SFSGTM_RS01980	ENOG4105C1Q	protoporphyrinogen oxidase
SFSGTM_RS02010	ENOG4105M2J	Glutaredoxin
SFSGTM_RS02025	ENOG4105VT3	DNA binding domain protein, excisionase family
SFSGTM_RS02065	ENOG4105K59	histidine triad (HIT) protein
SFSGTM_RS02070	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS02075	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS02110	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
SFSGTM_RS02115	ENOG4105D0B	Nitrogenase protein alpha chain
SFSGTM_RS02120	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
SFSGTM_RS02125	ENOG4105U82	Ferredoxin
SFSGTM_RS02130	ENOG4105U82	Ferredoxin
SFSGTM_RS02135	ENOG4105D0B	Nitrogenase protein alpha chain
SFSGTM_RS02140	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
SFSGTM_RS02145	ENOG4108UR2	Nitrogen fixation protein NifX
SFSGTM_RS02150	ENOG4108VQE	nitrogen fixation protein
SFSGTM_RS02155	ENOG4105X87	nitrogen fixation
SFSGTM_RS02160	ENOG4105WCA	Ferredoxin
SFSGTM_RS02180	ENOG4105F4R	Transcriptional regulator mode
SFSGTM_RS02185	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
SFSGTM_RS02195	ENOG4105E0C	molybdate abc transporter
SFSGTM_RS02200	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
SFSGTM_RS02220	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SFSGTM_RS02230	ENOG4105BZU	Histidine kinase
SFSGTM_RS02235	ENOG4105D58	Diguanylate phosphodiesterase
SFSGTM_RS02240	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SFSGTM_RS02245	ENOG4105BZU	Histidine kinase
SFSGTM_RS02255	ENOG4105PUF	Ferredoxin, 2FE-2S
SFSGTM_RS02260	ENOG4105KXW	Ferredoxin
SFSGTM_RS02265	ENOG4105KXW	Ferredoxin
SFSGTM_RS02270	ENOG4105CNW	domain protein
SFSGTM_RS02275	ENOG41090P5	ferredoxin-like protein
SFSGTM_RS02285	ENOG4105C10	Electron transfer flavoprotein
SFSGTM_RS02290	ENOG4105BZJ	Electron transfer flavoprotein
SFSGTM_RS02295	ENOG410605C	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
SFSGTM_RS02305	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
SFSGTM_RS02310	ENOG4108ZIT	Ferredoxin, 2FE-2S
SFSGTM_RS02315	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
SFSGTM_RS02320	ENOG4108Z4V	iron-sulfur cluster assembly
SFSGTM_RS02325	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
SFSGTM_RS02330	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
SFSGTM_RS02335	ENOG4105C3J	Cysteine desulfurase
SFSGTM_RS02345	ENOG4108JUA	Transcriptional regulator
SFSGTM_RS02365	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
SFSGTM_RS02370	ENOG4105CDU	Replicative dna helicase
SFSGTM_RS02380	ENOG4105C3R	Methionine synthase
SFSGTM_RS02390	ENOG4108UJU	UPF0301 protein
SFSGTM_RS02395	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
SFSGTM_RS02400	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
SFSGTM_RS02405	ENOG4105CXT	aspartate transcarbamylase
SFSGTM_RS02410	ENOG4105CD3	dihydroorotase
SFSGTM_RS02415	ENOG410890F	Dynamin family
SFSGTM_RS02420	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
SFSGTM_RS02440	ENOG4105C19	ABC transporter
SFSGTM_RS02445	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SFSGTM_RS02455	ENOG4105CKI	cobalamin synthesis protein
SFSGTM_RS02510	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
SFSGTM_RS02515	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
SFSGTM_RS02525	ENOG4105MH5	phosphoesterase PA-phosphatase related protein
SFSGTM_RS02535	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS02540	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS02545	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
SFSGTM_RS02555	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
SFSGTM_RS02565	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
SFSGTM_RS02585	ENOG4105IQ5	FAD linked oxidase domain protein
SFSGTM_RS02605	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS02610	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS02620	ENOG4105BZU	Histidine kinase
SFSGTM_RS02640	ENOG4108IPJ	Membrane
SFSGTM_RS02645	ENOG4105YES	addiction module antidote protein
SFSGTM_RS02650	ENOG4105VUH	addiction module killer protein
SFSGTM_RS02655	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
SFSGTM_RS02675	ENOG4105FFC	UPF0187 protein
SFSGTM_RS02680	ENOG4105EQR	Transposase IS116 IS110 IS902
SFSGTM_RS02690	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
SFSGTM_RS02695	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
SFSGTM_RS02700	ENOG4108Z43	UPF0250 protein
SFSGTM_RS02705	ENOG4105DZ1	carboxypeptidase
SFSGTM_RS02710	ENOG4105K6T	rare lipoprotein A
SFSGTM_RS02715	ENOG4105CNI	cell division protein FtsW
SFSGTM_RS02720	ENOG4105CJN	penicillin-binding protein
SFSGTM_RS02725	ENOG4105VQ7	Rod shape-determining protein MreD
SFSGTM_RS02730	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
SFSGTM_RS02740	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
SFSGTM_RS02745	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
SFSGTM_RS02750	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
SFSGTM_RS02775	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
SFSGTM_RS02780	ENOG4105CGK	Exodeoxyribonuclease III
SFSGTM_RS02785	ENOG4105EYM	Major Facilitator superfamily
SFSGTM_RS02795	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
SFSGTM_RS02805	ENOG4105ES5	Histidine kinase
SFSGTM_RS02820	ENOG4107T4Z	adenosine kinase
SFSGTM_RS02840	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
SFSGTM_RS02845	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
SFSGTM_RS02860	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
SFSGTM_RS02865	ENOG4108986	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
SFSGTM_RS02870	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
SFSGTM_RS02880	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
SFSGTM_RS02885	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
SFSGTM_RS02890	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
SFSGTM_RS02895	ENOG4105C3G	gtp-binding protein
SFSGTM_RS02915	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
SFSGTM_RS02925	ENOG4105PM1	preprotein translocase subunit SecE
SFSGTM_RS02930	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
SFSGTM_RS02935	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
SFSGTM_RS02940	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
SFSGTM_RS02945	ENOG4108VZM	50s ribosomal protein L10
SFSGTM_RS02950	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
SFSGTM_RS02955	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SFSGTM_RS02960	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SFSGTM_RS02965	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
SFSGTM_RS02970	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
SFSGTM_RS02975	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
SFSGTM_RS02980	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
SFSGTM_RS02985	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
SFSGTM_RS02990	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
SFSGTM_RS02995	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
SFSGTM_RS03000	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
SFSGTM_RS03005	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SFSGTM_RS03010	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
SFSGTM_RS03015	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
SFSGTM_RS03020	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
SFSGTM_RS03030	ENOG41084PQ	50s ribosomal protein l29
SFSGTM_RS03035	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
SFSGTM_RS03040	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
SFSGTM_RS03045	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
SFSGTM_RS03050	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SFSGTM_RS03055	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
SFSGTM_RS03060	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
SFSGTM_RS03065	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
SFSGTM_RS03070	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
SFSGTM_RS03075	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
SFSGTM_RS03080	ENOG4105VPB	50S ribosomal protein L30
SFSGTM_RS03090	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
SFSGTM_RS03095	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
SFSGTM_RS03100	ENOG41067V7	50S ribosomal protein L36
SFSGTM_RS03105	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SFSGTM_RS03110	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
SFSGTM_RS03115	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
SFSGTM_RS03120	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SFSGTM_RS03125	ENOG4108ZT0	50S ribosomal protein l17
SFSGTM_RS03130	ENOG4105C0D	helicase
SFSGTM_RS03135	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
SFSGTM_RS03140	ENOG4107RDB	Major Facilitator
SFSGTM_RS03145	ENOG4108UUM	single-stranded DNA-binding protein
SFSGTM_RS03150	ENOG4105BZU	Histidine kinase
SFSGTM_RS03160	ENOG4105C1J	atp-dependent rna helicase
SFSGTM_RS03175	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
SFSGTM_RS03190	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
SFSGTM_RS03195	ENOG4105K8N	protein family UPF0079, ATPase
SFSGTM_RS03200	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
SFSGTM_RS03205	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
SFSGTM_RS03215	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
SFSGTM_RS03220	ENOG4105FAW	cDP-glucose 4,6-dehydratase
SFSGTM_RS03225	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SFSGTM_RS03260	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
SFSGTM_RS03275	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
SFSGTM_RS03285	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
SFSGTM_RS03300	ENOG4105CKK	Glycosyl transferase, family 2
SFSGTM_RS03320	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
SFSGTM_RS03330	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
SFSGTM_RS03350	ENOG4105C5E	polysaccharide biosynthesis protein
SFSGTM_RS03355	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
SFSGTM_RS03365	ENOG4105UYK	outer membrane protein a
SFSGTM_RS03370	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
SFSGTM_RS03380	ENOG4105DNZ	Alpha Beta Hydrolase
SFSGTM_RS03385	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
SFSGTM_RS03395	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
SFSGTM_RS03400	ENOG4107YD3	Thioesterase
SFSGTM_RS03405	ENOG4105E02	MotA TolQ exbB proton channel
SFSGTM_RS03410	ENOG4105M8F	Biopolymer transport protein exbD tolR
SFSGTM_RS03420	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
SFSGTM_RS03425	ENOG4105KCK	Peptidoglycan-associated lipoprotein
SFSGTM_RS03435	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
SFSGTM_RS03440	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
SFSGTM_RS03445	ENOG4105CPI	Metal Dependent Phosphohydrolase
SFSGTM_RS03465	ENOG4105CGD	Nad-dependent epimerase dehydratase
SFSGTM_RS03475	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
SFSGTM_RS03485	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
SFSGTM_RS03490	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
SFSGTM_RS03530	ENOG4105BZU	Histidine kinase
SFSGTM_RS03535	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SFSGTM_RS03540	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
SFSGTM_RS03545	ENOG4105VEQ	Cold shock protein
SFSGTM_RS03555	ENOG4108R99	pseudouridine synthase
SFSGTM_RS03575	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
SFSGTM_RS03580	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
SFSGTM_RS03585	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
SFSGTM_RS03600	ENOG4105F4R	Transcriptional regulator mode
SFSGTM_RS03605	ENOG4108ZAF	Molybdopterin
SFSGTM_RS03610	ENOG4105M00	molybdopterin converting factor, subunit 1
SFSGTM_RS03615	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
SFSGTM_RS03620	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
SFSGTM_RS03625	ENOG4105CFP	Peptidase U32
SFSGTM_RS03630	ENOG4105CDY	transcriptional regulatory protein
SFSGTM_RS03645	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
SFSGTM_RS03650	ENOG4107YIM	Involved in the transcription termination process (By similarity)
SFSGTM_RS03655	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
SFSGTM_RS03660	ENOG4108ZAI	phosphatidylglycerophosphatase a
SFSGTM_RS03665	ENOG4107TH8	cina domain protein
SFSGTM_RS03670	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
SFSGTM_RS03675	ENOG4108004	Modulates RecA activity (By similarity)
SFSGTM_RS03680	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
SFSGTM_RS03690	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
SFSGTM_RS03695	ENOG4105C2N	RNA methyltransferase TrmH family group 3
SFSGTM_RS03700	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
SFSGTM_RS03710	ENOG4105CS6	Rhs element vgr protein
SFSGTM_RS03825	ENOG4105CS6	Rhs element vgr protein
SFSGTM_RS03870	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
SFSGTM_RS03875	ENOG4107W7X	Aldolase
SFSGTM_RS03880	ENOG4105C0H	protease
SFSGTM_RS03885	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SFSGTM_RS03890	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SFSGTM_RS03895	ENOG4105EIX	cytochrome c1
SFSGTM_RS03900	ENOG4107MKT	Stringent starvation protein a
SFSGTM_RS03905	ENOG4105KB2	stringent starvation protein b
SFSGTM_RS03920	ENOG4105CAQ	asparagine synthetase
SFSGTM_RS03945	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
SFSGTM_RS03950	ENOG4105VZ9	UPF0235 protein
SFSGTM_RS03955	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
SFSGTM_RS03960	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
SFSGTM_RS03965	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
SFSGTM_RS03970	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
SFSGTM_RS03975	ENOG4105DTN	riboflavin biosynthesis protein ribF
SFSGTM_RS03980	ENOG4105CJR	Integral membrane protein (MviN
SFSGTM_RS03985	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
SFSGTM_RS03995	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
SFSGTM_RS04000	ENOG4105C8Y	Acetylornithine aminotransferase
SFSGTM_RS04005	ENOG4105DBV	ornithine carbamoyltransferase
SFSGTM_RS04010	ENOG4105CDH	Citrulline--aspartate ligase
SFSGTM_RS04015	ENOG4105NBK	UPF0345 protein
SFSGTM_RS04030	ENOG4108VPT	UPF0234 protein
SFSGTM_RS04035	ENOG41080XP	Cbs domain
SFSGTM_RS04040	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
SFSGTM_RS04060	ENOG4105CQB	FAD linked oxidase domain protein
SFSGTM_RS04075	ENOG4105GJM	(LipO)protein
SFSGTM_RS04080	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
SFSGTM_RS04095	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
SFSGTM_RS04100	ENOG4105FE9	pseudouridine synthase
SFSGTM_RS04110	ENOG4107Z6W	Protein CrcB homolog
SFSGTM_RS04130	ENOG4105CQ7	ATP-dependent helicase
SFSGTM_RS04145	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
SFSGTM_RS04150	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
SFSGTM_RS04155	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
SFSGTM_RS04160	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
SFSGTM_RS04170	ENOG4105VW4	glutaredoxin 3
SFSGTM_RS04175	ENOG4107YZP	Rhodanese domain protein
SFSGTM_RS04185	ENOG4105BZS	acriflavin resistance protein
SFSGTM_RS04200	ENOG4105C1J	atp-dependent rna helicase
SFSGTM_RS04215	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
SFSGTM_RS04220	ENOG4105E0X	reductase
SFSGTM_RS04230	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
SFSGTM_RS04245	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
SFSGTM_RS04250	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
SFSGTM_RS04255	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
SFSGTM_RS04260	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
SFSGTM_RS04315	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
SFSGTM_RS04330	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS04335	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS04350	ENOG4105D1H	recombination factor protein RarA
SFSGTM_RS04355	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
SFSGTM_RS04360	ENOG4105CNU	cell division protein FtsK
SFSGTM_RS04365	ENOG4105C3M	thioredoxin reductase
SFSGTM_RS04370	ENOG4108DG9	Smr protein MutS2
SFSGTM_RS04375	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SFSGTM_RS04380	ENOG4108IAB	Phoh family
SFSGTM_RS04390	ENOG41067XF	inhibitor
SFSGTM_RS04395	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
SFSGTM_RS04400	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SFSGTM_RS04405	ENOG4105DY8	decarboxylase
SFSGTM_RS04430	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
SFSGTM_RS04435	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
SFSGTM_RS04440	ENOG4105K59	histidine triad (HIT) protein
SFSGTM_RS04445	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
SFSGTM_RS04450	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
SFSGTM_RS04455	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
SFSGTM_RS04460	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
SFSGTM_RS04465	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
SFSGTM_RS04470	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
SFSGTM_RS04475	ENOG4105CIH	Imidazole acetol-phosphate transaminase
SFSGTM_RS04480	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
SFSGTM_RS04490	ENOG4108ZUW	Major pilin subunit
SFSGTM_RS04495	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
SFSGTM_RS04500	ENOG4105D3R	alkyl hydroperoxide reductase
SFSGTM_RS04510	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
SFSGTM_RS04515	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
SFSGTM_RS04520	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SFSGTM_RS04525	ENOG4105CKK	Glycosyl transferase, family 2
SFSGTM_RS04530	ENOG4108M3P	Membrane
SFSGTM_RS04540	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
SFSGTM_RS04545	ENOG4108JU4	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
SFSGTM_RS04550	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
SFSGTM_RS04560	ENOG4105CC0	LysR family Transcriptional regulator
SFSGTM_RS04565	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
SFSGTM_RS04575	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
SFSGTM_RS04580	ENOG4105KUZ	arsenate reductase
SFSGTM_RS04585	ENOG41090R7	Ferric uptake
SFSGTM_RS04590	ENOG4105DFH	Transport of potassium into the cell (By similarity)
SFSGTM_RS04595	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
SFSGTM_RS04600	ENOG4105C08	Histidine kinase
SFSGTM_RS04605	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
SFSGTM_RS04610	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
SFSGTM_RS04620	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
SFSGTM_RS04625	ENOG4105DZ2	Transcriptional regulator
SFSGTM_RS04650	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SFSGTM_RS04655	ENOG4105BZS	acriflavin resistance protein
SFSGTM_RS04660	ENOG4105BZS	acriflavin resistance protein
SFSGTM_RS04675	ENOG4105C7Z	Conserved Protein
SFSGTM_RS04690	ENOG41082CH	UPF0145 protein
SFSGTM_RS04705	ENOG4105FQ6	thiopurine methyltransferase
SFSGTM_RS04710	ENOG4107SWG	transcriptional regulator MERR family
SFSGTM_RS04735	ENOG4105C4R	Atp-dependent dna helicase
SFSGTM_RS04740	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
SFSGTM_RS04755	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
SFSGTM_RS04760	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
SFSGTM_RS04765	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
SFSGTM_RS04775	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
SFSGTM_RS04780	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
SFSGTM_RS04790	ENOG4105EQ1	Transcriptional regulator
SFSGTM_RS04795	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
SFSGTM_RS04805	ENOG4105C3F	Signal peptidase i
SFSGTM_RS04810	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
SFSGTM_RS04820	ENOG4105C0H	protease
SFSGTM_RS04840	ENOG4105EMN	RNA polymerase sigma factor
SFSGTM_RS04850	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
SFSGTM_RS04855	ENOG4108R5S	membrane
SFSGTM_RS04865	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
SFSGTM_RS04870	ENOG4105C7S	Dehydrogenase
SFSGTM_RS04875	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
SFSGTM_RS04890	ENOG4105EPW	hflc protein
SFSGTM_RS04895	ENOG4107QJR	hflk protein
SFSGTM_RS04900	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
SFSGTM_RS04905	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
SFSGTM_RS04910	ENOG4107QP8	phosphohexose isomerase
SFSGTM_RS04915	ENOG4108V1T	peptidylprolyl cis-trans isomerase
SFSGTM_RS04925	ENOG4105CNG	UPF0061 protein
SFSGTM_RS04940	ENOG4105EYF	MMPL domain protein
SFSGTM_RS04945	ENOG4108M1M	outer membrane lipoprotein-sorting protein
SFSGTM_RS04950	ENOG4105CGH	5'-nucleotidase
SFSGTM_RS04960	ENOG4105NQN	cytochrome C
SFSGTM_RS04965	ENOG4105NQN	cytochrome C
SFSGTM_RS04980	ENOG4105CGH	5'-nucleotidase
SFSGTM_RS04985	ENOG4105CUC	YeeE YedE family protein
SFSGTM_RS04990	ENOG4105KFG	YeeE YedE family protein
SFSGTM_RS04995	ENOG4105DZB	Electron transport complex
SFSGTM_RS05010	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
SFSGTM_RS05015	ENOG4108R3D	Electron transport complex
SFSGTM_RS05020	ENOG4105DGN	Electron transport complex
SFSGTM_RS05025	ENOG4108JQB	penicillin-binding protein 1C
SFSGTM_RS05030	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
SFSGTM_RS05045	ENOG4107R0V	Pyruvate dehydrogenase
SFSGTM_RS05050	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
SFSGTM_RS05060	ENOG4108I69	Glycosyl transferases group 1
SFSGTM_RS05095	ENOG4105CMR	udp-glucose 4-epimerase
SFSGTM_RS05100	ENOG4105KJF	protein tyrosine phosphatase
SFSGTM_RS05105	ENOG4105C03	ribonuclease
SFSGTM_RS05110	ENOG4105EI2	Pseudouridine synthase
SFSGTM_RS05115	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SFSGTM_RS05130	ENOG4105JVQ	RNA Polymerase
SFSGTM_RS05145	ENOG41083MR	nifu domain-containing protein
SFSGTM_RS05150	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
SFSGTM_RS05160	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
SFSGTM_RS05165	ENOG4105PGM	cation diffusion facilitator family transporter
SFSGTM_RS05205	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
SFSGTM_RS05210	ENOG4108JJ7	ABC transporter
SFSGTM_RS05215	ENOG4105DSB	aldose 1-epimerase
SFSGTM_RS05220	ENOG4105E0X	reductase
SFSGTM_RS05255	ENOG4105CQB	FAD linked oxidase domain protein
SFSGTM_RS05260	ENOG4105EU8	FAD linked oxidase domain protein
SFSGTM_RS05265	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
SFSGTM_RS05295	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SFSGTM_RS05320	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
SFSGTM_RS05325	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
SFSGTM_RS05355	ENOG4105DGU	Histone deacetylase
SFSGTM_RS05370	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
SFSGTM_RS05410	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SFSGTM_RS05420	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
SFSGTM_RS05435	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
SFSGTM_RS05440	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SFSGTM_RS05445	ENOG4105EWM	Histidine kinase
SFSGTM_RS05450	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
SFSGTM_RS05455	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
SFSGTM_RS05465	ENOG4108YZA	Nitrogen regulatory protein pii
SFSGTM_RS05500	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS05505	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS05635	ENOG4107Z6I	Thiamine biosynthesis protein
SFSGTM_RS05640	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
SFSGTM_RS05655	ENOG4105MRR	Transcriptional regulator (By similarity)
SFSGTM_RS05660	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
SFSGTM_RS05670	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
SFSGTM_RS05680	ENOG4105BZU	Histidine kinase
SFSGTM_RS05685	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS05690	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS05700	ENOG4105BZU	Histidine kinase
SFSGTM_RS05710	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SFSGTM_RS05715	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SFSGTM_RS05720	ENOG4105CW7	secretion protein, HlyD family
SFSGTM_RS05725	ENOG410642W	LysR family Transcriptional regulator
SFSGTM_RS05735	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS05740	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS05770	ENOG4105CW7	secretion protein, HlyD family
SFSGTM_RS05775	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SFSGTM_RS05780	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SFSGTM_RS05785	ENOG4105BZU	Histidine kinase
SFSGTM_RS05805	ENOG4108IQE	Amp-dependent synthetase and ligase
SFSGTM_RS05815	ENOG4108W6C	Dehydrogenase
SFSGTM_RS05840	ENOG4106RE7	Cytochrome
SFSGTM_RS05845	ENOG4108UJV	acyl-CoA thioesterase i
SFSGTM_RS05850	ENOG4108I0Y	(ABC) transporter
SFSGTM_RS05855	ENOG4105CV6	ABC transporter, permease
SFSGTM_RS05860	ENOG4105BZU	Histidine kinase
SFSGTM_RS05875	ENOG41072GX	Peptidase M22 Glycoprotease
SFSGTM_RS05880	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
SFSGTM_RS05905	ENOG4108UHU	Aldolase
SFSGTM_RS05910	ENOG4105C01	Dihydroxy-acid dehydratase
SFSGTM_RS05915	ENOG4105FAE	von Willebrand factor, type A
SFSGTM_RS05920	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
SFSGTM_RS05925	ENOG4108Z1B	Cyclase dehydrase
SFSGTM_RS05930	ENOG4105VDB	UPF0125 protein
SFSGTM_RS05945	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
SFSGTM_RS05950	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
SFSGTM_RS05960	ENOG4105FAE	von Willebrand factor, type A
SFSGTM_RS05975	ENOG4105D2N	Aldolase
SFSGTM_RS05980	ENOG4105BZU	Histidine kinase
SFSGTM_RS05985	ENOG4105DVT	helicase
SFSGTM_RS05990	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
SFSGTM_RS06015	ENOG41082YX	Transcriptional regulator, arsr family
SFSGTM_RS06020	ENOG4108KUF	arsenical pump membrane protein
SFSGTM_RS06065	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
SFSGTM_RS06075	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
SFSGTM_RS06080	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
SFSGTM_RS06090	ENOG4108V1U	phospholipid-binding protein
SFSGTM_RS06095	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
SFSGTM_RS06110	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
SFSGTM_RS06115	ENOG4108EC8	DNA internalization-related competence protein ComEC
SFSGTM_RS06120	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
SFSGTM_RS06130	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
SFSGTM_RS06135	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
SFSGTM_RS06145	ENOG4107RD7	Flagellar Motor Protein, MotA
SFSGTM_RS06150	ENOG4105ER2	Ompa motb domain protein
SFSGTM_RS06175	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS06180	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS06200	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS06205	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS06225	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
SFSGTM_RS06230	ENOG4105N42	UPF0307 protein
SFSGTM_RS06235	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
SFSGTM_RS06250	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
SFSGTM_RS06260	ENOG4105D7Z	glutathione synthase
SFSGTM_RS06265	ENOG41081YB	ApbE family
SFSGTM_RS06280	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
SFSGTM_RS06285	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
SFSGTM_RS06295	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
SFSGTM_RS06300	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SFSGTM_RS06305	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
SFSGTM_RS06320	ENOG4107QVM	von Willebrand factor, type A
SFSGTM_RS06325	ENOG4107QVM	von Willebrand factor, type A
SFSGTM_RS06340	ENOG4105C5I	Dehydrogenase
SFSGTM_RS06355	ENOG4105BZU	Histidine kinase
SFSGTM_RS06365	ENOG4105EAC	phosphoserine phosphatase
SFSGTM_RS06370	ENOG4108JA2	transcriptioN-repair coupling factor
SFSGTM_RS06385	ENOG4105CHR	reductase
SFSGTM_RS06510	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS06515	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS06530	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS06535	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS06540	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
SFSGTM_RS06545	ENOG4105DUM	transcriptional regulator, lysR family
SFSGTM_RS06550	ENOG4105BZJ	Electron transfer flavoprotein
SFSGTM_RS06555	ENOG4105C10	Electron transfer flavoprotein
SFSGTM_RS06560	ENOG4105DP0	ferredoxin-NADP reductase
SFSGTM_RS06570	ENOG4107QUT	magnesium and cobalt transport protein CorA
SFSGTM_RS06625	ENOG4105PGM	cation diffusion facilitator family transporter
SFSGTM_RS06750	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
SFSGTM_RS06755	ENOG4105C08	Histidine kinase
SFSGTM_RS06770	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
SFSGTM_RS06775	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
SFSGTM_RS06780	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
SFSGTM_RS06855	ENOG4105CFH	Aspartokinase
SFSGTM_RS06860	ENOG4105ECY	inositol monophosphatase
SFSGTM_RS06880	ENOG4105C3J	Cysteine desulfurase
SFSGTM_RS06885	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
SFSGTM_RS06890	ENOG4108Z4V	iron-sulfur cluster assembly
SFSGTM_RS06895	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
SFSGTM_RS06900	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
SFSGTM_RS06905	ENOG4108ZIT	Ferredoxin, 2FE-2S
SFSGTM_RS06910	ENOG4105WVQ	Fe-S assembly protein IscX
SFSGTM_RS06920	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS06925	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS06955	ENOG4105E0F	Histidine kinase
SFSGTM_RS06965	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
SFSGTM_RS06970	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
SFSGTM_RS06980	ENOG4107WP9	Histidine kinase
SFSGTM_RS06990	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SFSGTM_RS07015	ENOG4105BZU	Histidine kinase
SFSGTM_RS07020	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SFSGTM_RS07025	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
SFSGTM_RS07035	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS07040	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS07050	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS07055	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS07075	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
SFSGTM_RS07080	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
SFSGTM_RS07100	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SFSGTM_RS07115	ENOG4107T5V	SNARE associated Golgi
SFSGTM_RS07120	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
SFSGTM_RS07125	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SFSGTM_RS07130	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
SFSGTM_RS07140	ENOG4105CIH	Imidazole acetol-phosphate transaminase
SFSGTM_RS07145	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
SFSGTM_RS07175	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SFSGTM_RS07220	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS07225	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS07240	ENOG4105BZU	Histidine kinase
SFSGTM_RS07250	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
SFSGTM_RS07265	ENOG4105CHR	reductase
SFSGTM_RS07305	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
SFSGTM_RS07320	ENOG4105C0Z	ABC transporter
SFSGTM_RS07325	ENOG4108IV0	ABC, transporter
SFSGTM_RS07330	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
SFSGTM_RS07335	ENOG4105FAE	von Willebrand factor, type A
SFSGTM_RS07340	ENOG4107R55	ethanolamine transporter
SFSGTM_RS07345	ENOG4105CPD	ethanolamine ammonia-lyase
SFSGTM_RS07350	ENOG4107FQ9	ethanolamine ammonia-lyase
SFSGTM_RS07360	ENOG4105C8Q	Methyl-accepting chemotaxis
SFSGTM_RS07365	ENOG4105BZU	Histidine kinase
SFSGTM_RS07375	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
SFSGTM_RS07380	ENOG4108YZ9	Urea amidohydrolase subunit gamma
SFSGTM_RS07385	ENOG4105KI2	Urea amidohydrolase subunit beta
SFSGTM_RS07390	ENOG4105CQM	Urea amidohydrolase subunit alpha
SFSGTM_RS07395	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
SFSGTM_RS07400	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
SFSGTM_RS07405	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
SFSGTM_RS07415	ENOG4108YZA	Nitrogen regulatory protein pii
SFSGTM_RS07420	ENOG4105BZU	Histidine kinase
SFSGTM_RS07425	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
SFSGTM_RS07430	ENOG4105CVE	Lytic murein transglycosylase
SFSGTM_RS07435	ENOG4105KT5	UmuD protein
SFSGTM_RS07440	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
SFSGTM_RS07500	ENOG4105VTR	Integrase
SFSGTM_RS07525	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
SFSGTM_RS07565	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
SFSGTM_RS07595	ENOG4108RDB	capsule polysaccharide export inner-membrane protein
SFSGTM_RS07615	ENOG4105E2K	Glycosyl transferase (Group 1
SFSGTM_RS07630	ENOG4105E12	capsule polysaccharide
SFSGTM_RS07660	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
SFSGTM_RS07665	ENOG41084CK	capsule polysaccharide
SFSGTM_RS07670	ENOG4105C11	sulfate adenylyltransferase), subunit 2
SFSGTM_RS07710	ENOG4105VTR	Integrase
SFSGTM_RS07755	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
SFSGTM_RS07775	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
SFSGTM_RS07860	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS07865	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS07890	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SFSGTM_RS07895	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SFSGTM_RS07910	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
SFSGTM_RS07920	ENOG4107QRI	Phosphoketolase
SFSGTM_RS07925	ENOG4107R1Y	fructose-bisphosphate aldolase
SFSGTM_RS07930	ENOG4107QP8	phosphohexose isomerase
SFSGTM_RS07970	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS07975	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS08005	ENOG4105DHJ	ABC, transporter
SFSGTM_RS08010	ENOG4105CY3	ABC transporter, permease
SFSGTM_RS08015	ENOG4107PE3	Mammalian cell entry related domain protein
SFSGTM_RS08035	ENOG4105DA5	(ABC) transporter
SFSGTM_RS08040	ENOG4105E3A	(ABC) transporter
SFSGTM_RS08050	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
SFSGTM_RS08055	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
SFSGTM_RS08065	ENOG4106WTF	Glycosyl transferase, family 2
SFSGTM_RS08070	ENOG4105CPK	Glycosyl transferase (Group 1
SFSGTM_RS08090	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS08095	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS08115	ENOG4107QPH	glycogen) synthase
SFSGTM_RS08120	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
SFSGTM_RS08125	ENOG4105VM1	flagellar
SFSGTM_RS08140	ENOG4105MQ3	flagellar protein FliS
SFSGTM_RS08145	ENOG4105DTS	flagellar hook-associated
SFSGTM_RS08160	ENOG4105BZU	Histidine kinase
SFSGTM_RS08165	ENOG4105WH1	Two component transcriptional regulator luxr family
SFSGTM_RS08170	ENOG4105BZU	Histidine kinase
SFSGTM_RS08180	ENOG4105C2C	drug resistance transporter, Bcr CflA
SFSGTM_RS08185	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
SFSGTM_RS08190	ENOG4105DN9	Na H antiporter
SFSGTM_RS08200	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
SFSGTM_RS08230	ENOG4105ERG	peptidase m48, ste24p
SFSGTM_RS08235	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
SFSGTM_RS08240	ENOG4105C6T	cysteine synthase
SFSGTM_RS08245	ENOG4108Z6B	deaminase
SFSGTM_RS08255	ENOG4105DFM	M18 family aminopeptidase
SFSGTM_RS08260	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
SFSGTM_RS08265	ENOG4105CHM	Aminotransferase
SFSGTM_RS08280	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
SFSGTM_RS08290	ENOG4105EMU	Dehydrogenase
SFSGTM_RS08300	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
SFSGTM_RS08330	ENOG4105CD5	CoA-binding domain protein
SFSGTM_RS08340	ENOG4107QWP	ABC-2 type transporter
SFSGTM_RS08350	ENOG4107QWP	ABC-2 type transporter
SFSGTM_RS08355	ENOG4105CJ1	ABC, transporter
SFSGTM_RS08365	ENOG4108C33	Resolvase
SFSGTM_RS08375	ENOG41063ES	
SFSGTM_RS08385	ENOG4105BZU	Histidine kinase
SFSGTM_RS08390	ENOG4105BZU	Histidine kinase
SFSGTM_RS08405	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
SFSGTM_RS08410	ENOG4105CTB	Polyprenyl synthetase
SFSGTM_RS08415	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
SFSGTM_RS08420	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
SFSGTM_RS08425	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
SFSGTM_RS08460	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS08465	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS08470	ENOG4108J2R	molybdopterin oxidoreductase
SFSGTM_RS08480	ENOG4105K70	DNA-binding protein
SFSGTM_RS08485	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
SFSGTM_RS08495	ENOG4107QUY	Guanine deaminase
SFSGTM_RS08510	ENOG4105UIB	(ABC) transporter
SFSGTM_RS08515	ENOG4108JQ9	ABC transporter
SFSGTM_RS08525	ENOG4105C7W	Xanthine dehydrogenase
SFSGTM_RS08535	ENOG4105VT2	5-hydroxyisourate hydrolase
SFSGTM_RS08540	ENOG4105DZC	cytosine deaminase
SFSGTM_RS08545	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
SFSGTM_RS08565	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
SFSGTM_RS08570	ENOG4105DHG	Allantoate amidinohydrolase
SFSGTM_RS08575	ENOG4108Z2U	ureidoglycolate hydrolase
SFSGTM_RS08585	ENOG4108RPX	mosc domain containing protein
SFSGTM_RS08600	ENOG4105E3B	Multicopper oxidase
SFSGTM_RS08610	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
SFSGTM_RS08645	ENOG4108JQ9	ABC transporter
SFSGTM_RS08680	ENOG4105BZU	Histidine kinase
SFSGTM_RS08685	ENOG4105CBC	glutamate synthase
SFSGTM_RS08690	ENOG4105M90	Glutamate synthase alpha subunit domain protein
SFSGTM_RS08695	ENOG4105EYU	Glutamine amido-transferase
SFSGTM_RS08710	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
SFSGTM_RS08725	ENOG4105CIY	formyltetrahydrofolate deformylase
SFSGTM_RS08755	ENOG4105D7K	pfkb domain protein
SFSGTM_RS08760	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
SFSGTM_RS08765	ENOG4106N16	had-superfamily hydrolase, subfamily iib
SFSGTM_RS08770	ENOG4107QW3	Sucrose phosphorylase
SFSGTM_RS08775	ENOG4105D8X	mechanosensitive ion channel
SFSGTM_RS08805	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
SFSGTM_RS08810	ENOG4105BZM	domain protein
SFSGTM_RS08830	ENOG4108YYC	ycei family
SFSGTM_RS08835	ENOG4105DS1	cytochrome b561
SFSGTM_RS08840	ENOG41090MY	MarR family Transcriptional regulator
SFSGTM_RS08850	ENOG4105CY0	Metallo-Beta-Lactamase
SFSGTM_RS08875	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
SFSGTM_RS08885	ENOG4108YZN	class I peptide chain release factor
SFSGTM_RS08950	ENOG4107S5T	Carbohydrate kinase
SFSGTM_RS08960	ENOG4105C31	Tryptophanyl-tRNA synthetase
SFSGTM_RS08965	ENOG4108Z4T	Peptidase M50
SFSGTM_RS08970	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
SFSGTM_RS08975	ENOG4105DB7	PHP domain protein
SFSGTM_RS08985	ENOG4107835	probably involved in intracellular septation (By similarity)
SFSGTM_RS08990	ENOG4105K9H	YciI-like protein
SFSGTM_RS09000	ENOG4107TF3	peptidylprolyl cis-trans isomerase
SFSGTM_RS09005	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
SFSGTM_RS09010	ENOG4105CD8	aminopeptidase N
SFSGTM_RS09015	ENOG4108JQ6	ABC transporter
SFSGTM_RS09020	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
SFSGTM_RS09025	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
SFSGTM_RS09035	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
SFSGTM_RS09040	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
SFSGTM_RS09060	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
SFSGTM_RS09065	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
SFSGTM_RS09070	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
SFSGTM_RS09075	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
SFSGTM_RS09095	ENOG4105DGU	Histone deacetylase
SFSGTM_RS09125	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
SFSGTM_RS09130	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
SFSGTM_RS09135	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS09140	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS09160	ENOG4105FE1	phytoene synthase
SFSGTM_RS09165	ENOG4105FE1	phytoene synthase
SFSGTM_RS09170	ENOG4107S11	squalene-associated FAD-dependent desaturase
SFSGTM_RS09175	ENOG4105UBK	short-chain dehydrogenase reductase
SFSGTM_RS09180	ENOG4105Y49	secretion protein, HlyD family
SFSGTM_RS09200	ENOG4108IJ0	Aspartate ammonia-lyase
SFSGTM_RS09220	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
SFSGTM_RS09235	ENOG4105CSR	polyphosphate kinase 2
SFSGTM_RS09240	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
SFSGTM_RS09245	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
SFSGTM_RS09250	ENOG4108Q71	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
SFSGTM_RS09260	ENOG4107T8V	it plays a direct role in the translocation of protons across the membrane (By similarity)
SFSGTM_RS09280	ENOG4105UHE	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
SFSGTM_RS09320	ENOG4107S2Z	UPF0761 membrane protein
SFSGTM_RS09325	ENOG4105CS1	NAD(P)H quinone oxidoreductase
SFSGTM_RS09335	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
SFSGTM_RS09350	ENOG4105FGV	Chromate
SFSGTM_RS09360	ENOG4105F9F	transposase
SFSGTM_RS09365	ENOG4105D3R	alkyl hydroperoxide reductase
SFSGTM_RS09375	ENOG4105CH5	extracellular solute-binding protein, family 7
SFSGTM_RS09380	ENOG4105CX6	glutaminyL-tRNA synthetase
SFSGTM_RS09385	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SFSGTM_RS09390	ENOG4105CFG	Acts as a chaperone (By similarity)
SFSGTM_RS09395	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SFSGTM_RS09410	ENOG4105F8V	Hydrolase, tatD family
SFSGTM_RS09420	ENOG4107QRG	dna polymerase iii
SFSGTM_RS09425	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
SFSGTM_RS09430	ENOG4105HHA	aminodeoxychorismate lyase
SFSGTM_RS09435	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
SFSGTM_RS09445	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
SFSGTM_RS09450	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SFSGTM_RS09455	ENOG4105CHR	reductase
SFSGTM_RS09460	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
SFSGTM_RS09470	ENOG4105VGS	50s ribosomal protein l32
SFSGTM_RS09475	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
SFSGTM_RS09480	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SFSGTM_RS09485	ENOG4107QSA	Oxaloacetate decarboxylase
SFSGTM_RS09490	ENOG4108UHJ	MAF-like protein
SFSGTM_RS09495	ENOG4105C5H	ABC transporter
SFSGTM_RS09500	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SFSGTM_RS09505	ENOG4105D1A	Methyltransferase
SFSGTM_RS09510	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
SFSGTM_RS09515	ENOG4105E9H	Lytic Murein transglycosylase
SFSGTM_RS09525	ENOG4105C98	muts2 protein
SFSGTM_RS09530	ENOG4106VK6	Flagellar motor protein
SFSGTM_RS09535	ENOG4105E14	MotA TolQ exbB proton channel
SFSGTM_RS09540	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SFSGTM_RS09550	ENOG4105FZW	flagellar biosynthesis regulator FlhF
SFSGTM_RS09555	ENOG4105D7B	Flagellar biosynthesis protein flha
SFSGTM_RS09560	ENOG4105D00	flagellar biosynthetic protein flhB
SFSGTM_RS09570	ENOG4105F8J	Adenylate Guanylate cyclase
SFSGTM_RS09575	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
SFSGTM_RS09580	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
SFSGTM_RS09595	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
SFSGTM_RS09600	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
SFSGTM_RS09605	ENOG4105CAT	Cytidine monophosphate kinase
SFSGTM_RS09610	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
SFSGTM_RS09615	ENOG4107RZZ	dna polymerase iii epsilon subunit
SFSGTM_RS09620	ENOG4105EW9	transcriptional regulator AsnC family
SFSGTM_RS09650	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS09655	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS09665	ENOG4106H3A	restriction
SFSGTM_RS09680	ENOG4108AWY	Nucleoside-diphosphate-sugar epimerase
SFSGTM_RS09690	ENOG4105DJ4	phosphatidylserine decarboxylase
SFSGTM_RS09700	ENOG4105BZU	Histidine kinase
SFSGTM_RS09705	ENOG4105C45	hydrogenase expression formation protein (HypE)
SFSGTM_RS09715	ENOG4105CQS	hydrogenase expression formation protein HypD
SFSGTM_RS09720	ENOG4107RSS	Hydrogenase accessory protein HypB
SFSGTM_RS09725	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
SFSGTM_RS09730	ENOG41083WG	hydrogenase assembly chaperone
SFSGTM_RS09740	ENOG4108UT5	Hydrogenase expression
SFSGTM_RS09745	ENOG4105E3S	small subunit
SFSGTM_RS09760	ENOG4105DPX	Hydrogenase, large subunit
SFSGTM_RS09765	ENOG4105BZU	Histidine kinase
SFSGTM_RS09770	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SFSGTM_RS09775	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
SFSGTM_RS09800	ENOG4105CPI	Metal Dependent Phosphohydrolase
SFSGTM_RS09805	ENOG4105BZU	Histidine kinase
SFSGTM_RS09815	ENOG4105DGU	Histone deacetylase
SFSGTM_RS09820	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
SFSGTM_RS09825	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
SFSGTM_RS09830	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
SFSGTM_RS09835	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SFSGTM_RS09840	ENOG4105CBX	hi0933 family
SFSGTM_RS09845	ENOG4105FE9	pseudouridine synthase
SFSGTM_RS09850	ENOG4105DDY	UPF0142 protein ycaO
SFSGTM_RS09890	ENOG4108DN8	FAD dependent oxidoreductase
SFSGTM_RS09895	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
SFSGTM_RS09900	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
SFSGTM_RS09905	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
SFSGTM_RS09910	ENOG4108CG0	Flagellar assembly protein
SFSGTM_RS09915	ENOG4108JIR	Flagellum-specific ATP synthase
SFSGTM_RS09930	ENOG4107ZI8	flagellar basal body-associated protein flil
SFSGTM_RS09935	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
SFSGTM_RS09940	ENOG4105DD5	Flagellar motor switch protein
SFSGTM_RS09945	ENOG4105K0P	flagellar biosynthesis protein
SFSGTM_RS09950	ENOG4105CN7	Flagellar biosynthetic protein FliP
SFSGTM_RS09960	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
SFSGTM_RS09970	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
SFSGTM_RS09975	ENOG4108VYJ	response regulator receiver protein
SFSGTM_RS09980	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
SFSGTM_RS09985	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
SFSGTM_RS09990	ENOG4105BZU	Histidine kinase
SFSGTM_RS09995	ENOG4105C8Q	Methyl-accepting chemotaxis
SFSGTM_RS10005	ENOG4105C8Q	Methyl-accepting chemotaxis
SFSGTM_RS10010	ENOG4105CPI	Metal Dependent Phosphohydrolase
SFSGTM_RS10015	ENOG4105C8Q	Methyl-accepting chemotaxis
SFSGTM_RS10020	ENOG4108V3W	Chemotaxis protein, CheW
SFSGTM_RS10025	ENOG4105CBS	Chea signal transduction histidine kinase
SFSGTM_RS10035	ENOG4105E1Q	flagellar hook-associated protein
SFSGTM_RS10040	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
SFSGTM_RS10045	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
SFSGTM_RS10050	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
SFSGTM_RS10055	ENOG4105CGA	flagellar basal-body rod protein FlgG
SFSGTM_RS10060	ENOG4108KPB	Flagellar basal-body rod protein FlgF
SFSGTM_RS10065	ENOG4105BZE	flagellar hook protein, FlgE
SFSGTM_RS10070	ENOG4105W00	Flagellar hook capping protein
SFSGTM_RS10075	ENOG4108ZC9	flagellar basal-body rod protein flgc
SFSGTM_RS10080	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
SFSGTM_RS10085	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
SFSGTM_RS10100	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
SFSGTM_RS10110	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
SFSGTM_RS10115	ENOG4105C34	Pseudouridine synthase
SFSGTM_RS10130	ENOG4105DJ0	Poly(A) Polymerase
SFSGTM_RS10135	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SFSGTM_RS10140	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
SFSGTM_RS10145	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
SFSGTM_RS10155	ENOG4105CRK	lysyL-tRNA synthetase
SFSGTM_RS10170	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
SFSGTM_RS10185	ENOG4108TIT	dATP pyrophosphohydrolase
SFSGTM_RS10200	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
SFSGTM_RS10205	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
SFSGTM_RS10210	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
SFSGTM_RS10220	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
SFSGTM_RS10245	ENOG4105M8F	Biopolymer transport protein exbD tolR
SFSGTM_RS10255	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
SFSGTM_RS10260	ENOG4105W49	UPF0434 protein
SFSGTM_RS10265	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
SFSGTM_RS10270	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
SFSGTM_RS10275	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
SFSGTM_RS10285	ENOG4108MN8	Membrane
SFSGTM_RS10290	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
SFSGTM_RS10295	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
SFSGTM_RS10300	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
SFSGTM_RS10310	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
SFSGTM_RS10315	ENOG4107XQ8	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
SFSGTM_RS10320	ENOG4105C12	Phosphoribosylglycinamide synthetase
SFSGTM_RS10325	ENOG4105DC1	bifunctional purine biosynthesis protein purh
SFSGTM_RS10330	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
SFSGTM_RS10335	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
SFSGTM_RS10360	ENOG4105SG9	biopolymer transport protein, ExbD
SFSGTM_RS10365	ENOG4108ESX	Receptor
SFSGTM_RS10370	ENOG4107E2E	PKHD-type hydroxylase
SFSGTM_RS10395	ENOG4105CHH	sulfate transporter
SFSGTM_RS10410	ENOG4108M8S	permease YjgP YjgQ family protein
SFSGTM_RS10415	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
SFSGTM_RS10445	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
SFSGTM_RS10460	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
SFSGTM_RS10465	ENOG41090Y2	cytochrome C
SFSGTM_RS10490	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS10495	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS10540	ENOG41066T0	asmA family
SFSGTM_RS10550	ENOG4105BZ4	penicillin-binding protein
SFSGTM_RS10585	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SFSGTM_RS10590	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SFSGTM_RS10595	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SFSGTM_RS10600	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
SFSGTM_RS10605	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SFSGTM_RS10615	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SFSGTM_RS10620	ENOG4105DZP	Membrane-associated zinc metalloprotease
SFSGTM_RS10625	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
SFSGTM_RS10630	ENOG4105KNE	Phosphatidate cytidylyltransferase
SFSGTM_RS10635	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
SFSGTM_RS10640	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
SFSGTM_RS10645	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
SFSGTM_RS10650	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
SFSGTM_RS10655	ENOG4105CE9	30S ribosomal protein S2
SFSGTM_RS10660	ENOG4105DZQ	phospholipase D Transphosphatidylase
SFSGTM_RS10665	ENOG4105X23	Endonuclease Exonuclease phosphatase
SFSGTM_RS10670	ENOG4105BZU	Histidine kinase
SFSGTM_RS10675	ENOG4107QHF	type ii secretion system protein e
SFSGTM_RS10680	ENOG4105D7Q	type ii secretion system
SFSGTM_RS10685	ENOG4105X0D	Fimbrial protein
SFSGTM_RS10755	ENOG4105C5H	ABC transporter
SFSGTM_RS10770	ENOG4105C5R	Aminotransferase
SFSGTM_RS10780	ENOG4107QM5	aconitate hydratase
SFSGTM_RS10790	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
SFSGTM_RS10795	ENOG4105D78	K07001 NTE family protein
SFSGTM_RS10815	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
SFSGTM_RS10830	ENOG4105CPC	Aldo Keto reductase
SFSGTM_RS10850	ENOG4105CND	Glycosyl transferase, family 2
SFSGTM_RS10885	ENOG4105BZ1	(ABC) transporter
SFSGTM_RS10905	ENOG4105D7A	ATP-binding protein
SFSGTM_RS10920	ENOG4105BZU	Histidine kinase
SFSGTM_RS10925	ENOG4105BZS	acriflavin resistance protein
SFSGTM_RS10930	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
SFSGTM_RS10940	ENOG4105NTK	Transcriptional repressor Mpra
SFSGTM_RS10950	ENOG4108V0P	LemA family
SFSGTM_RS10965	ENOG4105BZU	Histidine kinase
SFSGTM_RS10975	ENOG4105CXN	decarboxylase
SFSGTM_RS10980	ENOG4105DHP	deoxycytidine triphosphate deaminase
SFSGTM_RS10995	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
SFSGTM_RS11030	ENOG4105CM2	brancheD-chain amino acid aminotransferase
SFSGTM_RS11035	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
SFSGTM_RS11040	ENOG4105C6K	Malic enzyme
SFSGTM_RS11055	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
SFSGTM_RS11060	ENOG4108W15	Protein of unknown function (DUF1456)
SFSGTM_RS11065	ENOG4105C9U	ATP-dependent DNA helicase RecQ
SFSGTM_RS11070	ENOG4107QTF	adenylosuccinate lyase
SFSGTM_RS11075	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
SFSGTM_RS11100	ENOG4105EEQ	Na H antiporter
SFSGTM_RS11110	ENOG4105BZU	Histidine kinase
SFSGTM_RS11125	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SFSGTM_RS11130	ENOG4105BZU	Histidine kinase
SFSGTM_RS11135	ENOG4105D58	Diguanylate phosphodiesterase
SFSGTM_RS11140	ENOG4105D58	Diguanylate phosphodiesterase
SFSGTM_RS11145	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
SFSGTM_RS11155	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
SFSGTM_RS11160	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
SFSGTM_RS11165	ENOG4105VIE	preprotein translocase, subunit YajC
SFSGTM_RS11170	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
SFSGTM_RS11175	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
SFSGTM_RS11180	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
SFSGTM_RS11185	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SFSGTM_RS11195	ENOG4105DFP	Integrase
SFSGTM_RS11230	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS11235	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS11270	ENOG4105CPI	Metal Dependent Phosphohydrolase
SFSGTM_RS11275	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SFSGTM_RS11280	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SFSGTM_RS11285	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
SFSGTM_RS11290	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
SFSGTM_RS11305	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
SFSGTM_RS11310	ENOG4105D60	lipoprotein releasing system transmembrane protein
SFSGTM_RS11320	ENOG4105K4H	Nlp p60 protein
SFSGTM_RS11325	ENOG4105BZU	Histidine kinase
SFSGTM_RS11330	ENOG4105CMQ	Chloride channel
SFSGTM_RS11335	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
SFSGTM_RS11340	ENOG4108IYU	L-aspartate oxidase
SFSGTM_RS11345	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
SFSGTM_RS11355	ENOG4108Z18	K06886 hemoglobin
SFSGTM_RS11375	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
SFSGTM_RS11380	ENOG4105C4M	(Ubiquinol oxidase) subunit I
SFSGTM_RS11390	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SFSGTM_RS11395	ENOG4105BZU	Histidine kinase
SFSGTM_RS11405	ENOG4107RNH	Outer membrane receptor FepA
SFSGTM_RS11415	ENOG41079HR	Phosphate-Selective Porin O and P
SFSGTM_RS11465	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS11470	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS11475	ENOG4105VDW	Csbd family
SFSGTM_RS11520	ENOG4105CRE	cytochrome C
SFSGTM_RS11525	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SFSGTM_RS11535	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
SFSGTM_RS11540	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
SFSGTM_RS11550	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
SFSGTM_RS11555	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
SFSGTM_RS11560	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
SFSGTM_RS11570	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
SFSGTM_RS11575	ENOG4107TUY	Histidine kinase
SFSGTM_RS11585	ENOG4105EAH	synthase
SFSGTM_RS11590	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
SFSGTM_RS11595	ENOG4105K46	50S ribosomal protein l27
SFSGTM_RS11600	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SFSGTM_RS11605	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
SFSGTM_RS11610	ENOG4105E4C	Lytic transglycosylase catalytic
SFSGTM_RS11615	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
SFSGTM_RS11620	ENOG4105I7M	spermidine synthase
SFSGTM_RS11635	ENOG4105C8T	Leucyl-tRNA synthetase
SFSGTM_RS11640	ENOG4108U2H	Rare lipoprotein B
SFSGTM_RS11655	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SFSGTM_RS11660	ENOG4105CPW	cytochrome b561
SFSGTM_RS11675	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
SFSGTM_RS11680	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
SFSGTM_RS11685	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
SFSGTM_RS11690	ENOG4105K5M	30s ribosomal protein S16
SFSGTM_RS11695	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
SFSGTM_RS11700	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
SFSGTM_RS11705	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
SFSGTM_RS11715	ENOG4108C6U	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
SFSGTM_RS11720	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
SFSGTM_RS11725	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
SFSGTM_RS11730	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
SFSGTM_RS11735	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
SFSGTM_RS11740	ENOG4105BZU	Histidine kinase
SFSGTM_RS11750	ENOG4105BZU	Histidine kinase
SFSGTM_RS11775	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
SFSGTM_RS11785	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
SFSGTM_RS11790	ENOG4106UX7	integral membrane protein
SFSGTM_RS11795	ENOG4105C87	Aminotransferase class I and II
SFSGTM_RS11800	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
SFSGTM_RS11805	ENOG4105D3Q	Sugar transferase
SFSGTM_RS11870	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS11875	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS11890	ENOG4105NI8	Cytosine-specific methyltransferase
SFSGTM_RS11925	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SFSGTM_RS11940	ENOG4105VCC	30S ribosomal protein S21
SFSGTM_RS11945	ENOG4107QMP	dna polymerase iii subunits gamma and tau
SFSGTM_RS11955	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
SFSGTM_RS11965	ENOG4105BZU	Histidine kinase
SFSGTM_RS11970	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SFSGTM_RS11975	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
SFSGTM_RS11985	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
SFSGTM_RS12020	ENOG4107QHF	type ii secretion system protein e
SFSGTM_RS12030	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SFSGTM_RS12035	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SFSGTM_RS12135	ENOG4107X35	defense response to bacterium
SFSGTM_RS12145	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SFSGTM_RS12165	ENOG4108WC9	type VI secretion system effector, hcp1 family
SFSGTM_RS12295	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS12300	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS12305	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
SFSGTM_RS12310	ENOG4108J5G	6-phosphogluconate dehydrogenase
SFSGTM_RS12315	ENOG4108U78	Glutathione S-transferase
SFSGTM_RS12325	ENOG4105D6E	homoserine dehydrogenase
SFSGTM_RS12330	ENOG4105CHM	Aminotransferase
SFSGTM_RS12340	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
SFSGTM_RS12345	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SFSGTM_RS12350	ENOG4108K5P	(LipO)protein
SFSGTM_RS12355	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
SFSGTM_RS12360	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
SFSGTM_RS12380	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
SFSGTM_RS12385	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
SFSGTM_RS12390	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
SFSGTM_RS12395	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
SFSGTM_RS12400	ENOG4105VJV	50s ribosomal protein L35
SFSGTM_RS12405	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
SFSGTM_RS12410	ENOG4105C22	threonyL-tRNA synthetase
SFSGTM_RS12420	ENOG4105E6M	Sulphatase-modifying factor protein
SFSGTM_RS12425	ENOG4105F0N	pyrophosphate phospho-hydrolase
SFSGTM_RS12465	ENOG4107S74	Lysophospholipid transporter LplT
SFSGTM_RS12470	ENOG4105CEY	Amp-dependent synthetase and ligase
SFSGTM_RS12480	ENOG4105C1J	atp-dependent rna helicase
SFSGTM_RS12485	ENOG4105CI3	gtp-binding protein typa
SFSGTM_RS12490	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
SFSGTM_RS12495	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
SFSGTM_RS12510	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
SFSGTM_RS12515	ENOG4105CUT	histidyl-tRNA synthetase
SFSGTM_RS12525	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
SFSGTM_RS12530	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
SFSGTM_RS12540	ENOG4107QX8	SPFH domain, Band 7 family protein
SFSGTM_RS12575	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
SFSGTM_RS12580	ENOG4108JIC	nucleoside recognition domain protein
SFSGTM_RS12585	ENOG4105C9X	ppx gppa phosphatase
SFSGTM_RS12595	ENOG4108VWS	Yaeq family
SFSGTM_RS12625	ENOG4105C9M	aspartyl-trna synthetase
SFSGTM_RS12655	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SFSGTM_RS12660	ENOG41063SB	peptidase
SFSGTM_RS12665	ENOG4105CN1	protease
SFSGTM_RS12670	ENOG4105D06	uba thif-type nad fad binding protein
SFSGTM_RS12680	ENOG4105DHQ	Histidine kinase
SFSGTM_RS12685	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SFSGTM_RS12715	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
SFSGTM_RS12720	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
SFSGTM_RS12725	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
SFSGTM_RS12730	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
SFSGTM_RS12735	ENOG4108ZP8	Acetolactate synthase small subunit
SFSGTM_RS12740	ENOG4105C7K	acetolactate synthase
SFSGTM_RS12745	ENOG4105ERG	peptidase m48, ste24p
SFSGTM_RS12750	ENOG4105C2M	dna polymerase I
SFSGTM_RS12755	ENOG4108URH	decarboxylase
SFSGTM_RS12765	ENOG4105CUV	Homoserine Kinase
SFSGTM_RS12795	ENOG4105BZU	Histidine kinase
SFSGTM_RS12800	ENOG4105BZU	Histidine kinase
SFSGTM_RS12805	ENOG4105D6S	protein involved in catabolism of external DNA
SFSGTM_RS12810	ENOG4105CJB	Exodeoxyribonuclease I
SFSGTM_RS12825	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
SFSGTM_RS12830	ENOG4108ESY	Metal dependent phosphohydrolase
SFSGTM_RS12835	ENOG4105C8N	cysteinyl-tRNA synthetase
SFSGTM_RS12850	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
SFSGTM_RS12855	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
SFSGTM_RS12860	ENOG410901E	Membrane
SFSGTM_RS12870	ENOG4105C28	cystathionine
SFSGTM_RS12875	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
SFSGTM_RS12880	ENOG4105E96	Colicin v production protein
SFSGTM_RS12890	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
SFSGTM_RS12895	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
SFSGTM_RS12900	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
SFSGTM_RS12905	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
SFSGTM_RS12910	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
SFSGTM_RS12915	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
SFSGTM_RS12930	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
SFSGTM_RS12935	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
SFSGTM_RS12940	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
SFSGTM_RS12945	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SFSGTM_RS12950	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SFSGTM_RS12955	ENOG4105D8G	Major Facilitator superfamily
SFSGTM_RS12960	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
SFSGTM_RS12970	ENOG4105CSM	endonuclease III
SFSGTM_RS12990	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SFSGTM_RS12995	ENOG4105C8S	subunit m
SFSGTM_RS13005	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SFSGTM_RS13010	ENOG4105DF2	NADH dehydrogenase subunit j
SFSGTM_RS13015	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SFSGTM_RS13020	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
SFSGTM_RS13025	ENOG4108IEH	NADH dehydrogenase subunit g
SFSGTM_RS13030	ENOG4107QIZ	NADH dehydrogenase
SFSGTM_RS13040	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SFSGTM_RS13045	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SFSGTM_RS13055	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SFSGTM_RS13065	ENOG4105NTZ	Preprotein translocase subunit SecG
SFSGTM_RS13070	ENOG4105CP7	Triose-phosphate isomerase
SFSGTM_RS13075	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
SFSGTM_RS13080	ENOG4105C8U	phosphate abc transporter
SFSGTM_RS13085	ENOG4105E2Z	phosphate ABC transporter (Permease
SFSGTM_RS13090	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
SFSGTM_RS13095	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
SFSGTM_RS13100	ENOG4105EEI	dihydropteroate synthase
SFSGTM_RS13105	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SFSGTM_RS13110	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
SFSGTM_RS13130	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
SFSGTM_RS13135	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
SFSGTM_RS13160	ENOG4105BZ1	(ABC) transporter
SFSGTM_RS13165	ENOG4105EQR	Transposase IS116 IS110 IS902
SFSGTM_RS13175	ENOG4105C0B	DNA polymerase III (alpha subunit)
SFSGTM_RS13190	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS13195	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS13205	ENOG4105C72	UPF0176 protein
SFSGTM_RS13210	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
SFSGTM_RS13215	ENOG4105DFH	Transport of potassium into the cell (By similarity)
SFSGTM_RS13230	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
SFSGTM_RS13235	ENOG4105E50	uracil-dna glycosylase
SFSGTM_RS13240	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
SFSGTM_RS13245	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
SFSGTM_RS13270	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
SFSGTM_RS13275	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
SFSGTM_RS13280	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
SFSGTM_RS13285	ENOG4105CHV	Transcription elongation factor NusA
SFSGTM_RS13290	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
SFSGTM_RS13315	ENOG4107ZVW	dihydroneopterin aldolase
SFSGTM_RS13325	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS13330	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
SFSGTM_RS13340	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
SFSGTM_RS13345	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
SFSGTM_RS13350	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
SFSGTM_RS13355	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
SFSGTM_RS13360	ENOG4108Z03	MAF-like protein
SFSGTM_RS13365	ENOG4105C03	ribonuclease
SFSGTM_RS13380	ENOG4108VIA	integral membrane protein
SFSGTM_RS13385	ENOG4105II7	pyrroline-5-carboxylate reductase
SFSGTM_RS13390	ENOG4105DFA	alanine racemase domain protein
SFSGTM_RS13395	ENOG4105CZX	twitching motility protein
SFSGTM_RS13400	ENOG4105CZX	twitching motility protein
SFSGTM_RS13405	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
SFSGTM_RS13410	ENOG4108YXA	Membrane
SFSGTM_RS13415	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SFSGTM_RS13465	ENOG4105CQB	FAD linked oxidase domain protein
SFSGTM_RS13470	ENOG4107RIQ	Sulfate adenylate transferase
SFSGTM_RS13475	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
SFSGTM_RS13480	ENOG4105E4G	Type IV pilus
SFSGTM_RS13505	ENOG4108JQC	penicillin-binding protein 1A
SFSGTM_RS13515	ENOG4105D52	delta-aminolevulinic acid dehydratase
SFSGTM_RS13520	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
SFSGTM_RS13530	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
SFSGTM_RS13535	ENOG4105CRE	cytochrome C
SFSGTM_RS13540	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
SFSGTM_RS13545	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
SFSGTM_RS13555	ENOG4105VCQ	rubredoxin
SFSGTM_RS13560	ENOG4108UNF	response regulator
SFSGTM_RS13565	ENOG4105M3Z	response regulator
SFSGTM_RS13575	ENOG4105C8Q	Methyl-accepting chemotaxis
SFSGTM_RS13580	ENOG4105CBS	Chea signal transduction histidine kinase
SFSGTM_RS13585	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SFSGTM_RS13590	ENOG4105BZU	Histidine kinase
SFSGTM_RS13595	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
SFSGTM_RS13600	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
SFSGTM_RS13605	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
SFSGTM_RS13610	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
SFSGTM_RS13640	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
SFSGTM_RS13650	ENOG4105CHR	reductase
SFSGTM_RS13665	ENOG4105BZU	Histidine kinase
SFSGTM_RS13675	ENOG4105DSF	transport protein
SFSGTM_RS13710	ENOG4105CDV	Ompa motb domain protein
SFSGTM_RS13730	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
SFSGTM_RS13745	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SFSGTM_RS13750	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
SFSGTM_RS13755	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
SFSGTM_RS13760	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
SFSGTM_RS13765	ENOG4105CPF	Cell wall formation (By similarity)
SFSGTM_RS13770	ENOG4105D4A	Cell wall formation (By similarity)
SFSGTM_RS13775	ENOG4105DFU	Cell wall formation (By similarity)
SFSGTM_RS13780	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
SFSGTM_RS13785	ENOG4105CNI	cell division protein FtsW
SFSGTM_RS13790	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
SFSGTM_RS13795	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
SFSGTM_RS13800	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
SFSGTM_RS13805	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
SFSGTM_RS13810	ENOG4105CJN	penicillin-binding protein
SFSGTM_RS13815	ENOG4105N8N	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
SFSGTM_RS13820	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
SFSGTM_RS13825	ENOG4108V6E	Cell division protein mraZ
SFSGTM_RS13845	ENOG4105NWN	ApaG protein
SFSGTM_RS13850	ENOG4105DJV	ribulose-phosphate 3-epimerase
SFSGTM_RS13855	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SFSGTM_RS13865	ENOG4105DDQ	anthranilate synthase
SFSGTM_RS13870	ENOG4107QYG	anthranilate phosphoribosyltransferase
SFSGTM_RS13875	ENOG4105DK0	Indole-3-glycerol phosphate synthase
SFSGTM_RS13890	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS13895	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS13905	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
SFSGTM_RS13910	ENOG4105BZU	Histidine kinase
SFSGTM_RS13920	ENOG4105E0F	Histidine kinase
SFSGTM_RS13930	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
SFSGTM_RS13950	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
SFSGTM_RS13965	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
SFSGTM_RS13970	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
SFSGTM_RS13975	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
SFSGTM_RS13980	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
SFSGTM_RS13985	ENOG4105EHM	Aminoglycoside phosphotransferase
SFSGTM_RS13990	ENOG4108S0S	Nucleotidyl transferase
SFSGTM_RS14000	ENOG4107RAQ	aminopeptidase
SFSGTM_RS14005	ENOG4105D0A	hydroxylase
SFSGTM_RS14010	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
SFSGTM_RS14015	ENOG4105T95	Thiol disulfide interChange protein
SFSGTM_RS14025	ENOG4105BZU	Histidine kinase
SFSGTM_RS14030	ENOG4105BZU	Histidine kinase
SFSGTM_RS14040	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
SFSGTM_RS14070	ENOG4105PHD	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
SFSGTM_RS14080	ENOG4105RQ5	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
SFSGTM_RS14085	ENOG41086B8	CoB-CoM heterodisulfide reductase
SFSGTM_RS14115	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
SFSGTM_RS14120	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
SFSGTM_RS14125	ENOG4105C72	UPF0176 protein
SFSGTM_RS14130	ENOG4108KDI	dmso reductase anchor subunit
SFSGTM_RS14135	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SFSGTM_RS14140	ENOG4105DB1	molybdopterin oxidoreductase
SFSGTM_RS14155	ENOG4108JU6	CBS domain protein
SFSGTM_RS14160	ENOG4107QHF	type ii secretion system protein e
SFSGTM_RS14170	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
SFSGTM_RS14175	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
SFSGTM_RS14180	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
SFSGTM_RS14185	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
SFSGTM_RS14190	ENOG4105E66	phosphoriboisomerase A
SFSGTM_RS14195	ENOG4105C7B	Threonine dehydratase
SFSGTM_RS14200	ENOG4107SC1	transglycosylase
SFSGTM_RS14210	ENOG4105K63	Thioredoxin
SFSGTM_RS14215	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
SFSGTM_RS14220	ENOG4105CA3	membrane-bound lytic murein transglycosylase
SFSGTM_RS14230	ENOG4105BZU	Histidine kinase
SFSGTM_RS14240	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
SFSGTM_RS14245	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
SFSGTM_RS14250	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
SFSGTM_RS14255	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
SFSGTM_RS14260	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
SFSGTM_RS14270	ENOG4105MJ2	Competence protein
SFSGTM_RS14275	ENOG4105DHQ	Histidine kinase
SFSGTM_RS14280	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SFSGTM_RS14300	ENOG4105CH7	arginosuccinase
SFSGTM_RS14305	ENOG4108HRK	Histidine kinase
SFSGTM_RS14310	ENOG4108NEV	two component transcriptional regulator, LytTR family
SFSGTM_RS14320	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
SFSGTM_RS14335	ENOG4105I5W	Transporter
SFSGTM_RS14340	ENOG4108JUA	Transcriptional regulator
SFSGTM_RS14360	ENOG4105VCQ	rubredoxin
SFSGTM_RS14370	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
SFSGTM_RS14375	ENOG41076E6	Uroporphyrinogen-III Synthase
SFSGTM_RS14380	ENOG4105ECF	c-methyltransferase
SFSGTM_RS14400	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS14405	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS14415	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
SFSGTM_RS14430	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
SFSGTM_RS14445	ENOG4105BZU	Histidine kinase
SFSGTM_RS14450	ENOG4105E2V	Glycosyltransferase 36
SFSGTM_RS14480	ENOG4105EHU	Circadian clock protein KaiC
SFSGTM_RS14485	ENOG4105BZU	Histidine kinase
SFSGTM_RS14520	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
SFSGTM_RS14525	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
SFSGTM_RS14530	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
SFSGTM_RS14545	ENOG4105C4R	Atp-dependent dna helicase
SFSGTM_RS14550	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
SFSGTM_RS14585	ENOG4108Z20	Acyl-transferase
SFSGTM_RS14605	ENOG4105EKE	dihydroorotase
SFSGTM_RS14610	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
SFSGTM_RS14615	ENOG4105BZU	Histidine kinase
SFSGTM_RS14635	ENOG4105W0E	50S ribosomal protein L33
SFSGTM_RS14640	ENOG4105KDC	50s ribosomal protein l28
SFSGTM_RS14645	ENOG4105W5Q	DNA repair protein (RadC
SFSGTM_RS14655	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
SFSGTM_RS14665	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
SFSGTM_RS14670	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
SFSGTM_RS14675	ENOG41062IR	nudix hydrolase
SFSGTM_RS14690	ENOG4105DFU	Cell wall formation (By similarity)
SFSGTM_RS14695	ENOG4105D4P	Coproporphyrinogen iii oxidase
SFSGTM_RS14700	ENOG4105CBS	Chea signal transduction histidine kinase
SFSGTM_RS14705	ENOG4108V3W	Chemotaxis protein, CheW
SFSGTM_RS14710	ENOG4105C8Q	Methyl-accepting chemotaxis
SFSGTM_RS14720	ENOG4105C8Q	Methyl-accepting chemotaxis
SFSGTM_RS14725	ENOG4108VYJ	response regulator receiver protein
SFSGTM_RS14730	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
SFSGTM_RS14770	ENOG4105D7Q	type ii secretion system
SFSGTM_RS14775	ENOG4107QHF	type ii secretion system protein e
SFSGTM_RS14790	ENOG4106CJB	Phospholipase Carboxylesterase
SFSGTM_RS14795	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
SFSGTM_RS14800	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
SFSGTM_RS14805	ENOG4106H78	methyltransferase
SFSGTM_RS14825	ENOG4105CAK	Cell division ATP-binding protein ftsE
SFSGTM_RS14830	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
SFSGTM_RS14855	ENOG4105C58	cytochrome c oxidase accessory protein ccog
SFSGTM_RS14860	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
SFSGTM_RS14875	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
SFSGTM_RS14890	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
SFSGTM_RS14895	ENOG410807V	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
SFSGTM_RS14905	ENOG4105CB5	ATP-dependent DNA helicase recG
SFSGTM_RS14910	ENOG4105KME	endoribonuclease L-psp
SFSGTM_RS14920	ENOG4105DZ1	carboxypeptidase
SFSGTM_RS14925	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
SFSGTM_RS14930	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
SFSGTM_RS14935	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
SFSGTM_RS14950	ENOG4105DSJ	YicC domain protein
SFSGTM_RS14955	ENOG4107WDG	serine threonine protein kinase
SFSGTM_RS14960	ENOG4108ZF3	Phosphatase
SFSGTM_RS14965	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
SFSGTM_RS14970	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
SFSGTM_RS14975	ENOG4105CSA	Coproporphyrinogen iii oxidase
SFSGTM_RS14980	ENOG4105CUZ	uba thif-type nad fad binding protein
SFSGTM_RS15010	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
SFSGTM_RS15020	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
SFSGTM_RS15025	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
SFSGTM_RS15030	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
SFSGTM_RS15035	ENOG4108UJD	30S ribosomal protein S9
SFSGTM_RS15045	ENOG41080C8	DUF218 domain
SFSGTM_RS15050	ENOG4108UKZ	OsmC family
SFSGTM_RS15060	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
SFSGTM_RS15065	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
SFSGTM_RS15075	ENOG4108ZG0	Ompa motb domain protein
SFSGTM_RS15080	ENOG4108UT2	hemolysin iii
SFSGTM_RS15085	ENOG4107MBR	17 kDa surface antigen
SFSGTM_RS15110	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
SFSGTM_RS15115	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
SFSGTM_RS15135	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS15140	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS15150	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
SFSGTM_RS15175	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
SFSGTM_RS15190	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
SFSGTM_RS15195	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
SFSGTM_RS15200	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
SFSGTM_RS15205	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
SFSGTM_RS15210	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SFSGTM_RS15215	ENOG4108IUZ	ABC transporter
SFSGTM_RS15230	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
SFSGTM_RS15235	ENOG4105C2X	Arabinose 5-phosphate isomerase
SFSGTM_RS15245	ENOG4107SRH	Nad-dependent epimerase dehydratase
SFSGTM_RS15250	ENOG4108EX3	reductase
SFSGTM_RS15280	ENOG4105CS6	Rhs element vgr protein
SFSGTM_RS15410	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
SFSGTM_RS15420	ENOG41082AG	Plasmid maintenance system antidote protein
SFSGTM_RS15450	ENOG4105DBE	peroxidase
SFSGTM_RS15480	ENOG4105CHP	RNA polymerase
SFSGTM_RS15495	ENOG4105GRZ	Ycii-related protein
SFSGTM_RS15540	ENOG41063ES	
SFSGTM_RS15550	ENOG4108C33	Resolvase
SFSGTM_RS15570	ENOG4105EVH	UPF0753 protein
SFSGTM_RS15595	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
SFSGTM_RS15610	ENOG4105KNY	Microcompartments protein
SFSGTM_RS15615	ENOG4105KNY	Microcompartments protein
SFSGTM_RS15620	ENOG4105KNY	Microcompartments protein
SFSGTM_RS15645	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
SFSGTM_RS15650	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
SFSGTM_RS15655	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
SFSGTM_RS15695	ENOG4105CSR	polyphosphate kinase 2
SFSGTM_RS15700	ENOG4107PAI	alpha helical protein
SFSGTM_RS15720	ENOG4105BZU	Histidine kinase
SFSGTM_RS15725	ENOG4105M3Z	response regulator
SFSGTM_RS15730	ENOG4105EYW	Ion transport protein
SFSGTM_RS15755	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
SFSGTM_RS15795	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
SFSGTM_RS15805	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
SFSGTM_RS15810	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
SFSGTM_RS15820	ENOG4105C25	Primosomal protein n'
SFSGTM_RS15825	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
SFSGTM_RS15830	ENOG4105VTW	prevent-host-death family
SFSGTM_RS15845	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS15850	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS15875	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS15880	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SFSGTM_RS15900	ENOG4105CHR	reductase
SFSGTM_RS15930	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SFSGTM_RS15945	ENOG4105IPS	esterase
SFSGTM_RS15950	ENOG41061WM	D-Alanyl-D-Alanine
SFSGTM_RS15955	ENOG4105BZU	Histidine kinase
SFSGTM_RS15970	ENOG4105EMN	RNA polymerase sigma factor
SFSGTM_RS15985	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
SFSGTM_RS15990	ENOG4105D49	3-dehydroquinate synthase
SFSGTM_RS15995	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SFSGTM_RS16015	ENOG4105HAC	ABC-2 type transporter
SFSGTM_RS16035	ENOG4105DAN	ATP-dependent protease
SFSGTM_RS16040	ENOG4105CBC	glutamate synthase
SFSGTM_RS16045	ENOG4105BZ8	glutamate synthase
SFSGTM_RS16050	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
SFSGTM_RS16055	ENOG4105C2D	reductase
SFSGTM_RS16135	ENOG4105CEY	Amp-dependent synthetase and ligase
SFSGTM_RS16150	ENOG4105CAS	nag kinase
SFSGTM_RS16155	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
SFSGTM_RS16160	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
SFSGTM_RS16175	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
SFSGTM_RS16180	ENOG4105C5H	ABC transporter
SFSGTM_RS16185	ENOG4105BZU	Histidine kinase
SFSGTM_RS16195	ENOG4108EKC	n-acetylglutamate synthase
SFSGTM_RS16200	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
SFSGTM_RS16210	ENOG4105ECY	inositol monophosphatase
SFSGTM_RS16215	ENOG4105CV1	Transketolase (EC 2.2.1.1)
SFSGTM_RS16220	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
SFSGTM_RS16225	ENOG4105BZA	Phosphoglycerate kinase
SFSGTM_RS16230	ENOG4105CA9	Pyruvate kinase
SFSGTM_RS16235	ENOG4105D2N	Aldolase
SFSGTM_RS16240	ENOG4108JU5	Magnesium and cobalt efflux protein
SFSGTM_RS16245	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
SFSGTM_RS16250	ENOG4105C9A	Phoh family
SFSGTM_RS16255	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
SFSGTM_RS16265	ENOG4107ENK	receptor
SFSGTM_RS16270	ENOG4105IPI	Membrane
SFSGTM_RS16275	ENOG4105CEN	a g-specific adenine glycosylase
SFSGTM_RS16280	ENOG4105EYA	deoxyribonuclease
SFSGTM_RS16320	ENOG4108C33	Resolvase
SFSGTM_RS16325	ENOG4105VUH	addiction module killer protein
SFSGTM_RS16345	ENOG41061CK	Antibiotic biosynthesis monooxygenase
SFSGTM_RS16360	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
SFSGTM_RS16410	ENOG41077A9	carbonic anhydrase
SFSGTM_RS16425	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
SFSGTM_RS16435	ENOG4107BJW	polysaccharide deacetylase
SFSGTM_RS16440	ENOG4105CND	Glycosyl transferase, family 2
SFSGTM_RS16455	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
SFSGTM_RS16460	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SFSGTM_RS16465	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
SFSGTM_RS16470	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
SFSGTM_RS16475	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SFSGTM_RS16480	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
SFSGTM_RS16490	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
SFSGTM_RS16495	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
SFSGTM_RS16500	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
SFSGTM_RS16505	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
SFSGTM_RS16510	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SFSGTM_RS16515	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SFSGTM_RS16520	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SFSGTM_RS16525	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
SFSGTM_RS16535	ENOG4105FA0	parb-like partition protein
SFSGTM_RS16540	ENOG4107QJE	Chromosome Partitioning Protein
SFSGTM_RS16545	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
SFSGTM_RS16550	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
SFSGTM_RS16555	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
SFSGTM_RS16560	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
SFSGTM_RS16565	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
SFSGTM_RS16575	ENOG4105VG0	50S ribosomal protein l34
SFSGTM_RS16580	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
SFSGTM_RS16735	ENOG4105CS6	Rhs element vgr protein
SFSGTM_RS16755	ENOG4105YES	addiction module antidote protein
SFSGTM_RS16760	ENOG4105VUH	addiction module killer protein
SFSGTM_RS16780	ENOG41063ES	
SFSGTM_RS16790	ENOG4108C33	Resolvase
SFSGTM_RS16810	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SFSGTM_RS16820	ENOG4105WJ3	XRE family Transcriptional regulator
SFSGTM_RS16825	ENOG4105RT5	Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation
SFSGTM_RS16835	ENOG4105UKP	Protein of unknown function (DUF1778)
SFSGTM_RS16850	ENOG4105D5G	Transposase
SFSGTM_RS16855	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
SFSGTM_RS16875	ENOG4108C33	Resolvase
SFSGTM_RS16930	ENOG4108C33	Resolvase
SFSGTM_RS16940	ENOG41063ES