locus-tag	class	description
GZH91_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GZH91_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GZH91_RS00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GZH91_RS00020	ENOG4105K4P	CoA-binding domain protein
GZH91_RS00025	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GZH91_RS00040	ENOG4105CKI	cobalamin synthesis protein
GZH91_RS00050	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GZH91_RS00055	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GZH91_RS00060	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GZH91_RS00065	ENOG4105E0C	molybdate abc transporter
GZH91_RS00100	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
GZH91_RS00105	ENOG4105E2X	shikimate dehydrogenase
GZH91_RS00125	ENOG4105CUX	Signal transduction histidine kinase
GZH91_RS00130	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZH91_RS00145	ENOG4105RQ5	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GZH91_RS00160	ENOG4105CGK	Exodeoxyribonuclease III
GZH91_RS00170	ENOG4106F1P	AAA ATPase, central domain protein
GZH91_RS00175	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
GZH91_RS00180	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
GZH91_RS00195	ENOG4105DGW	oligopeptidase A
GZH91_RS00200	ENOG4108Z0R	Transferase
GZH91_RS00205	ENOG4105CD3	dihydroorotase
GZH91_RS00210	ENOG4105CXT	aspartate transcarbamylase
GZH91_RS00215	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
GZH91_RS00220	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GZH91_RS00225	ENOG4108UJU	UPF0301 protein
GZH91_RS00230	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GZH91_RS00245	ENOG4105IPS	esterase
GZH91_RS00275	ENOG4108JUA	Transcriptional regulator
GZH91_RS00280	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GZH91_RS00295	ENOG4105D7T	ABC transporter
GZH91_RS00300	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
GZH91_RS00305	ENOG4105BZU	Histidine kinase
GZH91_RS00315	ENOG4105DFU	Cell wall formation (By similarity)
GZH91_RS00360	ENOG4107SM8	Adenylate Guanylate cyclase
GZH91_RS00365	ENOG4105C0B	DNA polymerase III (alpha subunit)
GZH91_RS00380	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
GZH91_RS00385	ENOG4105SYT	Methylenetetrahydrofolate reductase
GZH91_RS00390	ENOG41086DT	Membrane protein of unknown function
GZH91_RS00395	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
GZH91_RS00400	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GZH91_RS00410	ENOG4105D1S	lipid A biosynthesis
GZH91_RS00420	ENOG4105GR3	Histidine kinase
GZH91_RS00425	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GZH91_RS00450	ENOG4108RPN	Protein smg homolog
GZH91_RS00455	ENOG4105C79	DNA protecting protein DprA
GZH91_RS00470	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GZH91_RS00500	ENOG4105CY3	ABC transporter, permease
GZH91_RS00510	ENOG4105DWV	Homoserine O-trans-acetylase
GZH91_RS00525	ENOG4105BZU	Histidine kinase
GZH91_RS00530	ENOG4108YZA	Nitrogen regulatory protein pii
GZH91_RS00540	ENOG4105W0Z	cytoplasmic protein
GZH91_RS00545	ENOG4105C0P	Mg chelatase subunit ChlI
GZH91_RS00550	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GZH91_RS00555	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GZH91_RS00560	ENOG4108Z43	UPF0250 protein
GZH91_RS00565	ENOG4105DZ1	carboxypeptidase
GZH91_RS00575	ENOG4105CNI	cell division protein FtsW
GZH91_RS00580	ENOG4105CJN	penicillin-binding protein
GZH91_RS00585	ENOG4105VQ7	Rod shape-determining protein MreD
GZH91_RS00600	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GZH91_RS00605	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GZH91_RS00610	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GZH91_RS00615	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GZH91_RS00635	ENOG4105BZU	Histidine kinase
GZH91_RS00640	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GZH91_RS00645	ENOG4108WQI	RNA Polymerase
GZH91_RS00650	ENOG4105VEQ	Cold shock protein
GZH91_RS00690	ENOG4105CYM	Glutathione S-transferase
GZH91_RS00695	ENOG4105WAP	TPR repeat-containing protein
GZH91_RS00700	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GZH91_RS00705	ENOG4105C1A	potassium transporter peripheral membrane
GZH91_RS00710	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZH91_RS00715	ENOG4105ES5	Histidine kinase
GZH91_RS00725	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GZH91_RS00735	ENOG4105EYM	Major Facilitator superfamily
GZH91_RS00740	ENOG4105CGK	Exodeoxyribonuclease III
GZH91_RS00745	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GZH91_RS00765	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GZH91_RS00770	ENOG4107ZT5	Thiol disulfide interchange protein
GZH91_RS00775	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GZH91_RS00780	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GZH91_RS00785	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GZH91_RS00790	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GZH91_RS00805	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GZH91_RS00810	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GZH91_RS00815	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GZH91_RS00820	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
GZH91_RS00825	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GZH91_RS00830	ENOG41080IJ	Diacylglycerol kinase
GZH91_RS00855	ENOG4105E3B	Multicopper oxidase
GZH91_RS00890	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
GZH91_RS00900	ENOG4107T4Z	adenosine kinase
GZH91_RS00915	ENOG4108Z20	Acyl-transferase
GZH91_RS00920	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GZH91_RS00925	ENOG4105C4R	Atp-dependent dna helicase
GZH91_RS00955	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GZH91_RS01000	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GZH91_RS01005	ENOG4105C02	permease
GZH91_RS01010	ENOG4105C8V	SAICAR synthetase
GZH91_RS01020	ENOG4105HF0	Membrane
GZH91_RS01055	ENOG4105CAS	nag kinase
GZH91_RS01065	ENOG4105E18	UPF0276 protein
GZH91_RS01075	ENOG4105CJW	magnesium transporter
GZH91_RS01080	ENOG4107QN2	dihydrolipoyl dehydrogenase
GZH91_RS01090	ENOG4105BZ1	(ABC) transporter
GZH91_RS01095	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GZH91_RS01105	ENOG4105C5R	Aminotransferase
GZH91_RS01110	ENOG4105C5H	ABC transporter
GZH91_RS01135	ENOG4105DHZ	alpha beta
GZH91_RS01150	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GZH91_RS01165	ENOG4108QV3	biosynthesis protein
GZH91_RS01180	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GZH91_RS01205	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GZH91_RS01210	ENOG4105CAQ	asparagine synthetase
GZH91_RS01220	ENOG4105E2K	Glycosyl transferase (Group 1
GZH91_RS01225	ENOG4105CPK	Glycosyl transferase (Group 1
GZH91_RS01260	ENOG4105F2I	Transposase
GZH91_RS01265	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GZH91_RS01295	ENOG4105K64	Glycosyl transferase, family 2
GZH91_RS01300	ENOG4107BJW	polysaccharide deacetylase
GZH91_RS01305	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
GZH91_RS01315	ENOG4105K64	Glycosyl transferase, family 2
GZH91_RS01325	ENOG4105D49	3-dehydroquinate synthase
GZH91_RS01330	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GZH91_RS01340	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GZH91_RS01345	ENOG4108I6A	alcohol dehydrogenase
GZH91_RS01350	ENOG4105MJ2	Competence protein
GZH91_RS01360	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GZH91_RS01365	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GZH91_RS01370	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GZH91_RS01375	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GZH91_RS01380	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GZH91_RS01390	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
GZH91_RS01395	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GZH91_RS01400	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
GZH91_RS01410	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
GZH91_RS01430	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GZH91_RS01440	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
GZH91_RS01455	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
GZH91_RS01460	ENOG4105C58	cytochrome c oxidase accessory protein ccog
GZH91_RS01470	ENOG4105C59	p-type ATPase
GZH91_RS01490	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GZH91_RS01495	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GZH91_RS01500	ENOG4105CAK	Cell division ATP-binding protein ftsE
GZH91_RS01520	ENOG4106H78	methyltransferase
GZH91_RS01525	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GZH91_RS01530	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GZH91_RS01540	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GZH91_RS01555	ENOG410642E	Short chain dehydrogenase
GZH91_RS01570	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GZH91_RS01575	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GZH91_RS01580	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GZH91_RS01585	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GZH91_RS01590	ENOG4105EHM	Aminoglycoside phosphotransferase
GZH91_RS01595	ENOG4108S0S	Nucleotidyl transferase
GZH91_RS01605	ENOG4107RAQ	aminopeptidase
GZH91_RS01610	ENOG4105D0A	hydroxylase
GZH91_RS01630	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GZH91_RS01635	ENOG4107QYG	anthranilate phosphoribosyltransferase
GZH91_RS01640	ENOG4105DDQ	anthranilate synthase
GZH91_RS01750	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GZH91_RS01755	ENOG4105DWV	Homoserine O-trans-acetylase
GZH91_RS01770	ENOG4105ES1	acyl-CoA reductase
GZH91_RS01775	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GZH91_RS01780	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GZH91_RS01795	ENOG4105DTI	Phosphonopyruvate decarboxylase
GZH91_RS01805	ENOG4105CPF	Cell wall formation (By similarity)
GZH91_RS01860	ENOG4105E3B	Multicopper oxidase
GZH91_RS01865	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GZH91_RS01895	ENOG4105PGM	cation diffusion facilitator family transporter
GZH91_RS01905	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GZH91_RS01920	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GZH91_RS01935	ENOG4105KT7	mgtC SapB transporter
GZH91_RS01980	ENOG4105KK4	UPF0060 membrane protein
GZH91_RS02025	ENOG4105KBH	arsR family transcriptional regulator
GZH91_RS02030	ENOG4107SJW	iron permease, FTR1
GZH91_RS02095	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GZH91_RS02155	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GZH91_RS02160	ENOG4105BZU	Histidine kinase
GZH91_RS02165	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GZH91_RS02190	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GZH91_RS02200	ENOG4108C33	Resolvase
GZH91_RS02215	ENOG4105E3B	Multicopper oxidase
GZH91_RS02220	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GZH91_RS02250	ENOG4105CSR	polyphosphate kinase 2
GZH91_RS02260	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GZH91_RS02290	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
GZH91_RS02305	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GZH91_RS02310	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GZH91_RS02325	ENOG4105EQR	Transposase IS116 IS110 IS902
GZH91_RS02330	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GZH91_RS02340	ENOG4105CKK	Glycosyl transferase, family 2
GZH91_RS02350	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GZH91_RS02380	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GZH91_RS02455	ENOG4105MPD	Cytochrome
GZH91_RS02480	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GZH91_RS02515	ENOG4107QKZ	Ompa motb domain protein
GZH91_RS02545	ENOG4105T95	Thiol disulfide interChange protein
GZH91_RS02625	ENOG4105DFP	Integrase
GZH91_RS02650	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GZH91_RS02660	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GZH91_RS02665	ENOG4105DJV	ribulose-phosphate 3-epimerase
GZH91_RS02670	ENOG4105NWN	ApaG protein
GZH91_RS02680	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GZH91_RS02695	ENOG4108Z9W	Outer membrane porin
GZH91_RS02725	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
GZH91_RS02735	ENOG4108UKZ	OsmC family
GZH91_RS02740	ENOG41080C8	DUF218 domain
GZH91_RS02745	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GZH91_RS02750	ENOG4108UJD	30S ribosomal protein S9
GZH91_RS02755	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GZH91_RS02760	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GZH91_RS02765	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GZH91_RS02775	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GZH91_RS02805	ENOG4105CUZ	uba thif-type nad fad binding protein
GZH91_RS02815	ENOG4105EYA	deoxyribonuclease
GZH91_RS02820	ENOG4105D8X	mechanosensitive ion channel
GZH91_RS02825	ENOG4105Q84	sucrose synthase
GZH91_RS02830	ENOG4107STW	synthase
GZH91_RS02845	ENOG4105CEN	a g-specific adenine glycosylase
GZH91_RS02860	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GZH91_RS02865	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GZH91_RS02870	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GZH91_RS02885	ENOG4105BZ8	glutamate synthase
GZH91_RS02905	ENOG4105ED1	spovr family
GZH91_RS02910	ENOG4106AKX	UPF0229 protein
GZH91_RS02915	ENOG4105CYN	Serine protein kinase
GZH91_RS02920	ENOG4105EUJ	GTP cyclohydrolase i
GZH91_RS02945	ENOG4108R5S	membrane
GZH91_RS02950	ENOG4105CSA	Coproporphyrinogen iii oxidase
GZH91_RS02960	ENOG4105CPI	Metal Dependent Phosphohydrolase
GZH91_RS02965	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GZH91_RS02970	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GZH91_RS02985	ENOG4105DSJ	YicC domain protein
GZH91_RS02990	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GZH91_RS02995	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GZH91_RS03000	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GZH91_RS03005	ENOG4105KME	endoribonuclease L-psp
GZH91_RS03010	ENOG4105CB5	ATP-dependent DNA helicase recG
GZH91_RS03020	ENOG410807V	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
GZH91_RS03025	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GZH91_RS03035	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
GZH91_RS03040	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GZH91_RS03085	ENOG4105K6V	RNA polymerase
GZH91_RS03095	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GZH91_RS03105	ENOG4105D7Z	glutathione synthase
GZH91_RS03110	ENOG41081YB	ApbE family
GZH91_RS03125	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GZH91_RS03140	ENOG4105VW4	glutaredoxin 3
GZH91_RS03145	ENOG4105WZW	rhodanese family
GZH91_RS03170	ENOG41080HT	Transcriptional regulator, arsr family
GZH91_RS03175	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GZH91_RS03180	ENOG41063SB	peptidase
GZH91_RS03185	ENOG4105CN1	protease
GZH91_RS03195	ENOG4105D06	uba thif-type nad fad binding protein
GZH91_RS03200	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GZH91_RS03205	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GZH91_RS03210	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GZH91_RS03215	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GZH91_RS03220	ENOG4105C8S	subunit m
GZH91_RS03225	ENOG4105D65	subunit l
GZH91_RS03230	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GZH91_RS03240	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GZH91_RS03245	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GZH91_RS03255	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GZH91_RS03270	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GZH91_RS03280	ENOG4105KTH	gatB Yqey
GZH91_RS03285	ENOG4105VCC	30S ribosomal protein S21
GZH91_RS03290	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GZH91_RS03300	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GZH91_RS03305	ENOG4107ZVW	dihydroneopterin aldolase
GZH91_RS03310	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GZH91_RS03315	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GZH91_RS03320	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GZH91_RS03325	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GZH91_RS03330	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GZH91_RS03335	ENOG4105K5M	30s ribosomal protein S16
GZH91_RS03340	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GZH91_RS03345	ENOG4105CRE	cytochrome C
GZH91_RS03350	ENOG4108JU6	CBS domain protein
GZH91_RS03355	ENOG4107QHF	type ii secretion system protein e
GZH91_RS03365	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GZH91_RS03370	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GZH91_RS03375	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GZH91_RS03395	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
GZH91_RS03400	ENOG4105E66	phosphoriboisomerase A
GZH91_RS03405	ENOG4105C7B	Threonine dehydratase
GZH91_RS03410	ENOG4107SC1	transglycosylase
GZH91_RS03420	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GZH91_RS03440	ENOG4105E0F	Histidine kinase
GZH91_RS03450	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
GZH91_RS03455	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GZH91_RS03460	ENOG4105BZU	Histidine kinase
GZH91_RS03465	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GZH91_RS03485	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
GZH91_RS03490	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GZH91_RS03500	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GZH91_RS03505	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GZH91_RS03510	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GZH91_RS03515	ENOG4105C3G	gtp-binding protein
GZH91_RS03535	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GZH91_RS03545	ENOG4105PM1	preprotein translocase subunit SecE
GZH91_RS03550	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GZH91_RS03555	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GZH91_RS03560	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GZH91_RS03565	ENOG4108VZM	50s ribosomal protein L10
GZH91_RS03570	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GZH91_RS03575	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GZH91_RS03580	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GZH91_RS03585	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GZH91_RS03590	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GZH91_RS03595	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GZH91_RS03600	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GZH91_RS03605	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GZH91_RS03610	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GZH91_RS03615	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GZH91_RS03620	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GZH91_RS03625	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GZH91_RS03635	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GZH91_RS03640	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GZH91_RS03645	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GZH91_RS03650	ENOG41084PQ	50s ribosomal protein l29
GZH91_RS03655	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GZH91_RS03660	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GZH91_RS03665	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GZH91_RS03670	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GZH91_RS03675	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GZH91_RS03680	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GZH91_RS03685	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GZH91_RS03690	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GZH91_RS03695	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GZH91_RS03700	ENOG4105VPB	50S ribosomal protein L30
GZH91_RS03705	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GZH91_RS03710	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GZH91_RS03715	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GZH91_RS03720	ENOG41067V7	50S ribosomal protein L36
GZH91_RS03725	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GZH91_RS03730	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GZH91_RS03735	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GZH91_RS03740	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GZH91_RS03745	ENOG4108ZT0	50S ribosomal protein l17
GZH91_RS03760	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GZH91_RS03765	ENOG4107RDB	Major Facilitator
GZH91_RS03770	ENOG4108UUM	single-stranded DNA-binding protein
GZH91_RS03775	ENOG4105CEY	Amp-dependent synthetase and ligase
GZH91_RS03795	ENOG4105C9M	aspartyl-trna synthetase
GZH91_RS03805	ENOG4108TIT	dATP pyrophosphohydrolase
GZH91_RS03810	ENOG4105BZU	Histidine kinase
GZH91_RS03815	ENOG4105X23	Endonuclease Exonuclease phosphatase
GZH91_RS03820	ENOG4105DZQ	phospholipase D Transphosphatidylase
GZH91_RS03850	ENOG4105CDY	transcriptional regulatory protein
GZH91_RS03855	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GZH91_RS03860	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GZH91_RS03865	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GZH91_RS03870	ENOG4107YD3	Thioesterase
GZH91_RS03875	ENOG4105E02	MotA TolQ exbB proton channel
GZH91_RS03880	ENOG4105M8F	Biopolymer transport protein exbD tolR
GZH91_RS03890	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GZH91_RS03900	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GZH91_RS03910	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GZH91_RS03915	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GZH91_RS03925	ENOG4105N42	UPF0307 protein
GZH91_RS03930	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GZH91_RS03935	ENOG4105DDY	UPF0142 protein ycaO
GZH91_RS03960	ENOG4107TPS	domain protein
GZH91_RS03970	ENOG4107QV8	Conserved hypothetical protein 698
GZH91_RS04005	ENOG4105CPK	Glycosyl transferase (Group 1
GZH91_RS04010	ENOG4108004	Modulates RecA activity (By similarity)
GZH91_RS04015	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GZH91_RS04020	ENOG4107TH8	cina domain protein
GZH91_RS04025	ENOG4108ZAI	phosphatidylglycerophosphatase a
GZH91_RS04030	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GZH91_RS04035	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GZH91_RS04040	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GZH91_RS04055	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GZH91_RS04060	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GZH91_RS04065	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GZH91_RS04075	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GZH91_RS04090	ENOG4108Z18	K06886 hemoglobin
GZH91_RS04110	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
GZH91_RS04120	ENOG4105C9X	ppx gppa phosphatase
GZH91_RS04130	ENOG4105I7R	Adenylate cyclase
GZH91_RS04135	ENOG410902C	phosphohistidine phosphatase, SixA
GZH91_RS04140	ENOG4108VYJ	response regulator receiver protein
GZH91_RS04145	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GZH91_RS04150	ENOG4105GJM	(LipO)protein
GZH91_RS04165	ENOG4105C1J	atp-dependent rna helicase
GZH91_RS04195	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GZH91_RS04200	ENOG4105E0X	reductase
GZH91_RS04205	ENOG4108RAC	Rubrerythrin
GZH91_RS04210	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GZH91_RS04225	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GZH91_RS04235	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GZH91_RS04240	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GZH91_RS04245	ENOG4105K46	50S ribosomal protein l27
GZH91_RS04250	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GZH91_RS04255	ENOG4105EAH	synthase
GZH91_RS04270	ENOG4107TUY	Histidine kinase
GZH91_RS04275	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZH91_RS04310	ENOG4108UQY	Iron-storage protein
GZH91_RS04320	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GZH91_RS04335	ENOG41079HR	Phosphate-Selective Porin O and P
GZH91_RS04355	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GZH91_RS04360	ENOG4105DZ2	Transcriptional regulator
GZH91_RS04365	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GZH91_RS04370	ENOG4105J0Q	Transcriptional regulator
GZH91_RS04385	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GZH91_RS04390	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GZH91_RS04395	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GZH91_RS04430	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
GZH91_RS04440	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GZH91_RS04445	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GZH91_RS04450	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GZH91_RS04460	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GZH91_RS04465	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
GZH91_RS04475	ENOG4105EPW	hflc protein
GZH91_RS04480	ENOG4107QJR	hflk protein
GZH91_RS04485	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GZH91_RS04490	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GZH91_RS04495	ENOG4105BZU	Histidine kinase
GZH91_RS04505	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GZH91_RS04520	ENOG4105CUT	histidyl-tRNA synthetase
GZH91_RS04525	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GZH91_RS04540	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GZH91_RS04545	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GZH91_RS04550	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GZH91_RS04555	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GZH91_RS04560	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GZH91_RS04570	ENOG4105EZE	Cupin 4 family protein
GZH91_RS04585	ENOG4105EQR	Transposase IS116 IS110 IS902
GZH91_RS04595	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GZH91_RS04610	ENOG4108VWS	Yaeq family
GZH91_RS04615	ENOG4108UPT	UPF0178 protein
GZH91_RS04625	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
GZH91_RS04680	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GZH91_RS04690	ENOG410841Q	phosphoesterase PA-phosphatase related protein
GZH91_RS04705	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
GZH91_RS04710	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GZH91_RS04720	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GZH91_RS04725	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GZH91_RS04730	ENOG4105D1H	recombination factor protein RarA
GZH91_RS04735	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
GZH91_RS04740	ENOG4105CNU	cell division protein FtsK
GZH91_RS04745	ENOG4105C3M	thioredoxin reductase
GZH91_RS04750	ENOG4108DG9	Smr protein MutS2
GZH91_RS04755	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GZH91_RS04760	ENOG4108IAB	Phoh family
GZH91_RS04790	ENOG4105C5H	ABC transporter
GZH91_RS04805	ENOG4107FSV	UPF0391 membrane protein
GZH91_RS04810	ENOG4105CPC	Aldo Keto reductase
GZH91_RS04815	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GZH91_RS04820	ENOG4105C2C	drug resistance transporter, Bcr CflA
GZH91_RS04830	ENOG4105BZU	Histidine kinase
GZH91_RS04855	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GZH91_RS04865	ENOG4105DCG	PHP domain protein
GZH91_RS04870	ENOG4105C5H	ABC transporter
GZH91_RS04880	ENOG4105C0A	alcohol dehydrogenase
GZH91_RS04955	ENOG4105W39	Membrane
GZH91_RS04985	ENOG4105CRK	lysyL-tRNA synthetase
GZH91_RS05005	ENOG4105WVQ	Fe-S assembly protein IscX
GZH91_RS05010	ENOG4108ZIT	Ferredoxin, 2FE-2S
GZH91_RS05015	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GZH91_RS05020	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GZH91_RS05030	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GZH91_RS05035	ENOG4105C3J	Cysteine desulfurase
GZH91_RS05055	ENOG4105ECY	inositol monophosphatase
GZH91_RS05060	ENOG4105CFH	Aspartokinase
GZH91_RS05090	ENOG4105BZS	acriflavin resistance protein
GZH91_RS05095	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
GZH91_RS05100	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GZH91_RS05105	ENOG4105FS7	Transcriptional regulator
GZH91_RS05115	ENOG4105DEN	Luciferase family
GZH91_RS05125	ENOG4105CW7	secretion protein, HlyD family
GZH91_RS05130	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GZH91_RS05155	ENOG4105BZU	Histidine kinase
GZH91_RS05160	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GZH91_RS05165	ENOG4105BZU	Histidine kinase
GZH91_RS05180	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GZH91_RS05190	ENOG4108TGR	phosphatase
GZH91_RS05195	ENOG4105CHH	sulfate transporter
GZH91_RS05200	ENOG4105MH5	phosphoesterase PA-phosphatase related protein
GZH91_RS05205	ENOG4105C4W	S-formylglutathione hydrolase
GZH91_RS05210	ENOG4107QPD	alcohol dehydrogenase
GZH91_RS05215	ENOG4108ESY	Metal dependent phosphohydrolase
GZH91_RS05250	ENOG4105DAY	polysaccharide export protein
GZH91_RS05280	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
GZH91_RS05290	ENOG4105D7W	serine acetyltransferase
GZH91_RS05315	ENOG4105CMR	udp-glucose 4-epimerase
GZH91_RS05320	ENOG4105DSF	transport protein
GZH91_RS05340	ENOG4105NQN	cytochrome C
GZH91_RS05345	ENOG41090Y2	cytochrome C
GZH91_RS05365	ENOG4105VDW	Csbd family
GZH91_RS05385	ENOG4105D8G	Major Facilitator superfamily
GZH91_RS05390	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GZH91_RS05400	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GZH91_RS05405	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GZH91_RS05410	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GZH91_RS05415	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GZH91_RS05430	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GZH91_RS05435	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
GZH91_RS05440	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GZH91_RS05450	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GZH91_RS05455	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GZH91_RS05460	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GZH91_RS05470	ENOG4105E96	Colicin v production protein
GZH91_RS05475	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GZH91_RS05480	ENOG4105C28	cystathionine
GZH91_RS05490	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GZH91_RS05495	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GZH91_RS05500	ENOG4105C8N	cysteinyl-tRNA synthetase
GZH91_RS05520	ENOG4105DHJ	ABC, transporter
GZH91_RS05525	ENOG4105CY3	ABC transporter, permease
GZH91_RS05530	ENOG4107PE3	Mammalian cell entry related domain protein
GZH91_RS05550	ENOG4105DA5	(ABC) transporter
GZH91_RS05555	ENOG4105E3A	(ABC) transporter
GZH91_RS05565	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GZH91_RS05570	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GZH91_RS05580	ENOG4105DKP	glycosyl transferase, family 9
GZH91_RS05585	ENOG4107TYR	Glycosyl Transferase
GZH91_RS05590	ENOG4105CAQ	asparagine synthetase
GZH91_RS05620	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GZH91_RS05625	ENOG4105KHS	type IV fimbrial pilin protein
GZH91_RS05665	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
GZH91_RS05670	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GZH91_RS05675	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
GZH91_RS05680	ENOG4105VTW	prevent-host-death family
GZH91_RS05685	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GZH91_RS05690	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GZH91_RS05695	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GZH91_RS05700	ENOG4105DTN	riboflavin biosynthesis protein ribF
GZH91_RS05705	ENOG4105CJR	Integral membrane protein (MviN
GZH91_RS05750	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GZH91_RS05755	ENOG4105BZU	Histidine kinase
GZH91_RS05760	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GZH91_RS05770	ENOG4109015	Biopolymer transport protein exbD tolR
GZH91_RS05780	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GZH91_RS05785	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GZH91_RS05790	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GZH91_RS05795	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GZH91_RS05805	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
GZH91_RS05815	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GZH91_RS05820	ENOG4105CH6	catalase
GZH91_RS05835	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
GZH91_RS05840	ENOG4108YYC	ycei family
GZH91_RS05845	ENOG4105CC0	LysR family Transcriptional regulator
GZH91_RS05880	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
GZH91_RS05885	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
GZH91_RS05890	ENOG4105I5W	Transporter
GZH91_RS05895	ENOG4105D7T	ABC transporter
GZH91_RS05920	ENOG4107QVI	Methyltransferase, type 11
GZH91_RS05925	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
GZH91_RS05935	ENOG4105DND	Transcriptional regulator
GZH91_RS05955	ENOG4105EMU	Dehydrogenase
GZH91_RS05965	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GZH91_RS05970	ENOG4105CHR	reductase
GZH91_RS05990	ENOG4105C0D	helicase
GZH91_RS05995	ENOG4105I3K	Ferric uptake regulator, Fur family
GZH91_RS06000	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GZH91_RS06005	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GZH91_RS06010	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GZH91_RS06015	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GZH91_RS06020	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GZH91_RS06025	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GZH91_RS06030	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GZH91_RS06035	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
GZH91_RS06040	ENOG4105K59	histidine triad (HIT) protein
GZH91_RS06045	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GZH91_RS06050	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GZH91_RS06065	ENOG4105EQ1	Transcriptional regulator
GZH91_RS06070	ENOG4105C72	UPF0176 protein
GZH91_RS06075	ENOG4105C0B	DNA polymerase III (alpha subunit)
GZH91_RS06085	ENOG4108RXX	maleylacetoacetate isomerase
GZH91_RS06095	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GZH91_RS06105	ENOG4107QM5	aconitate hydratase
GZH91_RS06135	ENOG4105PWE	CRISPR-associated protein cas2
GZH91_RS06140	ENOG4105E39	Enoyl-CoA hydratase
GZH91_RS06145	ENOG4105BZU	Histidine kinase
GZH91_RS06150	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZH91_RS06155	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GZH91_RS06160	ENOG4105C6K	Malic enzyme
GZH91_RS06180	ENOG4105E33	succinate dehydrogenase
GZH91_RS06185	ENOG4105Y75	tpr repeat protein
GZH91_RS06190	ENOG4105BZN	citrate synthase
GZH91_RS06195	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GZH91_RS06200	ENOG4105C7S	Dehydrogenase
GZH91_RS06210	ENOG4105VN1	Heat shock protein
GZH91_RS06220	ENOG4105BZU	Histidine kinase
GZH91_RS06230	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
GZH91_RS06235	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
GZH91_RS06245	ENOG4107RD7	Flagellar Motor Protein, MotA
GZH91_RS06250	ENOG4105ER2	Ompa motb domain protein
GZH91_RS06255	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GZH91_RS06265	ENOG4105BZU	Histidine kinase
GZH91_RS06270	ENOG4105D00	flagellar biosynthetic protein flhB
GZH91_RS06275	ENOG4105D7B	Flagellar biosynthesis protein flha
GZH91_RS06280	ENOG4105FZW	flagellar biosynthesis regulator FlhF
GZH91_RS06290	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GZH91_RS06295	ENOG4105E14	MotA TolQ exbB proton channel
GZH91_RS06300	ENOG4105ER2	Ompa motb domain protein
GZH91_RS06325	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GZH91_RS06330	ENOG4108ZC9	flagellar basal-body rod protein flgc
GZH91_RS06335	ENOG4105W00	Flagellar hook capping protein
GZH91_RS06340	ENOG4105BZE	flagellar hook protein, FlgE
GZH91_RS06345	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GZH91_RS06350	ENOG4105CGA	flagellar basal-body rod protein FlgG
GZH91_RS06355	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GZH91_RS06360	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GZH91_RS06365	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GZH91_RS06370	ENOG4105E1Q	flagellar hook-associated protein
GZH91_RS06375	ENOG4105DTJ	flagellar hook-associated protein
GZH91_RS06385	ENOG4108VYJ	response regulator receiver protein
GZH91_RS06390	ENOG4105CBS	Chea signal transduction histidine kinase
GZH91_RS06395	ENOG4108V3W	Chemotaxis protein, CheW
GZH91_RS06400	ENOG4105C8Q	Methyl-accepting chemotaxis
GZH91_RS06405	ENOG4105C8Q	Methyl-accepting chemotaxis
GZH91_RS06410	ENOG4105BZU	Histidine kinase
GZH91_RS06415	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
GZH91_RS06420	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GZH91_RS06425	ENOG4108VYJ	response regulator receiver protein
GZH91_RS06430	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GZH91_RS06440	ENOG4105BZU	Histidine kinase
GZH91_RS06445	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GZH91_RS06455	ENOG4105CN7	Flagellar biosynthetic protein FliP
GZH91_RS06465	ENOG4105DD5	Flagellar motor switch protein
GZH91_RS06470	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GZH91_RS06490	ENOG4108JIR	Flagellum-specific ATP synthase
GZH91_RS06500	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GZH91_RS06505	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GZH91_RS06510	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GZH91_RS06515	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
GZH91_RS06520	ENOG4105D00	flagellar biosynthetic protein flhB
GZH91_RS06530	ENOG4105YXP	it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity)
GZH91_RS06540	ENOG4105DTS	flagellar hook-associated
GZH91_RS06540	ENOG4105DTS	flagellar hook-associated
GZH91_RS06580	ENOG4108J5G	6-phosphogluconate dehydrogenase
GZH91_RS06595	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GZH91_RS06600	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GZH91_RS06620	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GZH91_RS06630	ENOG4107PAI	alpha helical protein
GZH91_RS06635	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
GZH91_RS06650	ENOG4107QKZ	Ompa motb domain protein
GZH91_RS06680	ENOG4108XG2	Histidine kinase
GZH91_RS06685	ENOG4105WH1	Two component transcriptional regulator luxr family
GZH91_RS06690	ENOG4105BZU	Histidine kinase
GZH91_RS06725	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GZH91_RS06730	ENOG4105F0N	pyrophosphate phospho-hydrolase
GZH91_RS06745	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GZH91_RS06760	ENOG4105EWK	phytoene
GZH91_RS06775	ENOG41086B8	CoB-CoM heterodisulfide reductase
GZH91_RS06785	ENOG4105E6M	Sulphatase-modifying factor protein
GZH91_RS06800	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GZH91_RS06805	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GZH91_RS06815	ENOG4108YZA	Nitrogen regulatory protein pii
GZH91_RS06825	ENOG4105C34	Pseudouridine synthase
GZH91_RS06830	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GZH91_RS06835	ENOG4105CFU	surface antigen
GZH91_RS06845	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GZH91_RS06855	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GZH91_RS06880	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GZH91_RS06885	ENOG4105GFR	rna polymerase sigma factor
GZH91_RS06890	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GZH91_RS06895	ENOG4105KHU	inner membrane protein YohD
GZH91_RS06910	ENOG4105BZU	Histidine kinase
GZH91_RS06915	ENOG4105K4H	Nlp p60 protein
GZH91_RS06925	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GZH91_RS06945	ENOG4106KE4	Dehydrogenase
GZH91_RS06950	ENOG4105DQ4	alcohol dehydrogenase
GZH91_RS06960	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GZH91_RS06965	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GZH91_RS06970	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
GZH91_RS06985	ENOG4105BZS	acriflavin resistance protein
GZH91_RS06990	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GZH91_RS07000	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GZH91_RS07005	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GZH91_RS07020	ENOG41090R7	Ferric uptake
GZH91_RS07025	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GZH91_RS07030	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GZH91_RS07035	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GZH91_RS07040	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GZH91_RS07045	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GZH91_RS07055	ENOG4105HBR	Rna-binding protein
GZH91_RS07060	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GZH91_RS07065	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GZH91_RS07070	ENOG4105EEI	dihydropteroate synthase
GZH91_RS07075	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GZH91_RS07080	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GZH91_RS07085	ENOG4105E2Z	phosphate ABC transporter (Permease
GZH91_RS07090	ENOG4105C8U	phosphate abc transporter
GZH91_RS07100	ENOG4105CP7	Triose-phosphate isomerase
GZH91_RS07105	ENOG4105NTZ	Preprotein translocase subunit SecG
GZH91_RS07115	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GZH91_RS07120	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GZH91_RS07125	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GZH91_RS07130	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GZH91_RS07140	ENOG4107QIZ	NADH dehydrogenase
GZH91_RS07145	ENOG4108IEH	NADH dehydrogenase subunit g
GZH91_RS07150	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GZH91_RS07155	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GZH91_RS07160	ENOG4105DF2	NADH dehydrogenase subunit j
GZH91_RS07165	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GZH91_RS07175	ENOG4105C8S	subunit m
GZH91_RS07180	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GZH91_RS07190	ENOG4107QHF	type ii secretion system protein e
GZH91_RS07200	ENOG4105D7Q	type ii secretion system
GZH91_RS07210	ENOG4105KHS	type IV fimbrial pilin protein
GZH91_RS07215	ENOG4105KHS	type IV fimbrial pilin protein
GZH91_RS07220	ENOG4106855	Competence protein
GZH91_RS07305	ENOG4108RG0	uracil-dna glycosylase
GZH91_RS07365	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZH91_RS07370	ENOG4105BZU	Histidine kinase
GZH91_RS07380	ENOG4105DP0	ferredoxin-NADP reductase
GZH91_RS07390	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GZH91_RS07395	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GZH91_RS07400	ENOG4105K8N	protein family UPF0079, ATPase
GZH91_RS07405	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GZH91_RS07410	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GZH91_RS07420	ENOG4105CGH	5'-nucleotidase
GZH91_RS07425	ENOG4105C1J	atp-dependent rna helicase
GZH91_RS07455	ENOG4105C87	Aminotransferase class I and II
GZH91_RS07470	ENOG4108WBT	adenosyltransferase
GZH91_RS07475	ENOG4105N7H	Cytochrome
GZH91_RS07480	ENOG4106RE7	Cytochrome
GZH91_RS07495	ENOG4105CSM	endonuclease III
GZH91_RS07515	ENOG4105CQB	FAD linked oxidase domain protein
GZH91_RS07540	ENOG4107QP8	phosphohexose isomerase
GZH91_RS07545	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GZH91_RS07550	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GZH91_RS07560	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
GZH91_RS07565	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GZH91_RS07575	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GZH91_RS07605	ENOG4105ERG	peptidase m48, ste24p
GZH91_RS07610	ENOG4105F8J	Adenylate Guanylate cyclase
GZH91_RS07645	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GZH91_RS07650	ENOG4105GR3	Histidine kinase
GZH91_RS07655	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GZH91_RS07660	ENOG4105E3B	Multicopper oxidase
GZH91_RS07680	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GZH91_RS07685	ENOG4108MN8	Membrane
GZH91_RS07690	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GZH91_RS07725	ENOG4105DZB	Electron transport complex
GZH91_RS07735	ENOG4105D6A	Electron transport complex
GZH91_RS07740	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
GZH91_RS07745	ENOG4108R3D	Electron transport complex
GZH91_RS07750	ENOG4105DGN	Electron transport complex
GZH91_RS07755	ENOG4105DCF	alanine dehydrogenase
GZH91_RS07760	ENOG4105BZ4	penicillin-binding protein
GZH91_RS07765	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GZH91_RS07790	ENOG4105DZ1	carboxypeptidase
GZH91_RS07805	ENOG4107R0V	Pyruvate dehydrogenase
GZH91_RS07810	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GZH91_RS07815	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GZH91_RS07820	ENOG4105BZU	Histidine kinase
GZH91_RS07825	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
GZH91_RS07840	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GZH91_RS07845	ENOG4105C8Y	Acetylornithine aminotransferase
GZH91_RS07850	ENOG4105DBV	ornithine carbamoyltransferase
GZH91_RS07855	ENOG4105CDH	Citrulline--aspartate ligase
GZH91_RS07860	ENOG4105NBK	UPF0345 protein
GZH91_RS07865	ENOG4108VPT	UPF0234 protein
GZH91_RS07880	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GZH91_RS07885	ENOG41090A4	Pterin carbinolamine dehydratase
GZH91_RS07895	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
GZH91_RS07900	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GZH91_RS07905	ENOG4108WIW	Aspartyl protease
GZH91_RS07910	ENOG4105FE9	pseudouridine synthase
GZH91_RS07920	ENOG41066T0	asmA family
GZH91_RS07935	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GZH91_RS07940	ENOG4105CJB	Exodeoxyribonuclease I
GZH91_RS07950	ENOG4105F2I	Transposase
GZH91_RS07970	ENOG4105C32	Amino acid ABC transporter (Permease)
GZH91_RS07980	ENOG4105C0Z	ABC transporter
GZH91_RS07985	ENOG4108IV0	ABC, transporter
GZH91_RS08010	ENOG4105D01	(LipO)protein
GZH91_RS08015	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
GZH91_RS08030	ENOG4105EIG	urea carboxylase-associated protein 1
GZH91_RS08035	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GZH91_RS08050	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
GZH91_RS08065	ENOG4105CHR	reductase
GZH91_RS08115	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GZH91_RS08120	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
GZH91_RS08125	ENOG4108EC8	DNA internalization-related competence protein ComEC
GZH91_RS08130	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GZH91_RS08160	ENOG4105IJJ	transcriptional regulator, crp fnr family
GZH91_RS08185	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GZH91_RS08190	ENOG41081A3	ATP synthase f0, c subunit
GZH91_RS08195	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GZH91_RS08200	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GZH91_RS08205	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GZH91_RS08215	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GZH91_RS08220	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GZH91_RS08225	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GZH91_RS08260	ENOG4105CA0	peroxidase
GZH91_RS08275	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
GZH91_RS08280	ENOG4105D7T	ABC transporter
GZH91_RS08290	ENOG4105D7T	ABC transporter
GZH91_RS08315	ENOG4108ZX6	Electron transport protein SCO1 SenC
GZH91_RS08340	ENOG4105BZU	Histidine kinase
GZH91_RS08345	ENOG4108ZXC	Two component transcriptional regulator, luxr family
GZH91_RS08355	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GZH91_RS08375	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GZH91_RS08380	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GZH91_RS08390	ENOG4105C22	threonyL-tRNA synthetase
GZH91_RS08395	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GZH91_RS08400	ENOG4105VJV	50s ribosomal protein L35
GZH91_RS08405	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GZH91_RS08410	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GZH91_RS08415	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GZH91_RS08420	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GZH91_RS08435	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GZH91_RS08440	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GZH91_RS08445	ENOG4108K5P	(LipO)protein
GZH91_RS08450	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GZH91_RS08455	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
GZH91_RS08465	ENOG4105CHM	Aminotransferase
GZH91_RS08470	ENOG4105D6E	homoserine dehydrogenase
GZH91_RS08480	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GZH91_RS08485	ENOG4105DVT	helicase
GZH91_RS08495	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GZH91_RS08520	ENOG4105DFH	Transport of potassium into the cell (By similarity)
GZH91_RS08535	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
GZH91_RS08540	ENOG41067HS	methyltransferase
GZH91_RS08550	ENOG4105EHV	domain protein
GZH91_RS08555	ENOG4105DC8	reductase
GZH91_RS08590	ENOG4105DPX	Hydrogenase, large subunit
GZH91_RS08645	ENOG4105C8H	hydrogenase maturation protein Hypf
GZH91_RS08660	ENOG4105CQS	hydrogenase expression formation protein HypD
GZH91_RS08665	ENOG4105C45	hydrogenase expression formation protein (HypE)
GZH91_RS08675	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
GZH91_RS08685	ENOG4105D9G	High-affinity
GZH91_RS08730	ENOG4105F4R	Transcriptional regulator mode
GZH91_RS08735	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GZH91_RS08750	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GZH91_RS08755	ENOG4107TF3	peptidylprolyl cis-trans isomerase
GZH91_RS08765	ENOG4105K9H	YciI-like protein
GZH91_RS08770	ENOG4107835	probably involved in intracellular septation (By similarity)
GZH91_RS08780	ENOG4105DB7	PHP domain protein
GZH91_RS08785	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GZH91_RS08790	ENOG4108Z4T	Peptidase M50
GZH91_RS08795	ENOG4105C31	Tryptophanyl-tRNA synthetase
GZH91_RS08800	ENOG4105BZU	Histidine kinase
GZH91_RS08805	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZH91_RS08815	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GZH91_RS08820	ENOG4108MG3	formate dehydrogenase
GZH91_RS08825	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
GZH91_RS08830	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
GZH91_RS08835	ENOG4105EM7	Selenocysteine-specific translation elongation factor
GZH91_RS08845	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
GZH91_RS08850	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GZH91_RS08855	ENOG4105FE9	pseudouridine synthase
GZH91_RS08875	ENOG4105BZU	Histidine kinase
GZH91_RS08880	ENOG4108U78	Glutathione S-transferase
GZH91_RS08900	ENOG4105EMN	RNA polymerase sigma factor
GZH91_RS08910	ENOG4108J5G	6-phosphogluconate dehydrogenase
GZH91_RS08915	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GZH91_RS08920	ENOG4105C0H	protease
GZH91_RS08925	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GZH91_RS08930	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GZH91_RS08935	ENOG4105EIX	cytochrome c1
GZH91_RS08940	ENOG4107MKT	Stringent starvation protein a
GZH91_RS08945	ENOG4105KB2	stringent starvation protein b
GZH91_RS08960	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GZH91_RS08975	ENOG4108JJ7	ABC transporter
GZH91_RS08980	ENOG4105DSB	aldose 1-epimerase
GZH91_RS09005	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
GZH91_RS09035	ENOG4105D3R	alkyl hydroperoxide reductase
GZH91_RS09050	ENOG4105C59	p-type ATPase
GZH91_RS09100	ENOG4105C2D	reductase
GZH91_RS09115	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GZH91_RS09175	ENOG4107S5T	Carbohydrate kinase
GZH91_RS09180	ENOG4108YZN	class I peptide chain release factor
GZH91_RS09185	ENOG4105C7Z	Conserved Protein
GZH91_RS09200	ENOG4108ZX6	Electron transport protein SCO1 SenC
GZH91_RS09210	ENOG4105DFG	type I secretion outer membrane protein
GZH91_RS09215	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
GZH91_RS09250	ENOG4108JJA	ABC, transporter
GZH91_RS09255	ENOG4105CSR	polyphosphate kinase 2
GZH91_RS09260	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GZH91_RS09275	ENOG4107QVM	von Willebrand factor, type A
GZH91_RS09280	ENOG4107QVM	von Willebrand factor, type A
GZH91_RS09300	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
GZH91_RS09315	ENOG4108KS2	transglutaminase domain protein
GZH91_RS09335	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GZH91_RS09365	ENOG4108Z6B	deaminase
GZH91_RS09370	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
GZH91_RS09375	ENOG4108NWD	Cytochrome
GZH91_RS09380	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
GZH91_RS09385	ENOG4107YZX	Universal stress protein
GZH91_RS09390	ENOG4107R1Y	fructose-bisphosphate aldolase
GZH91_RS09405	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GZH91_RS09410	ENOG4105CW7	secretion protein, HlyD family
GZH91_RS09415	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
GZH91_RS09435	ENOG4108Z4U	Ferredoxin
GZH91_RS09440	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GZH91_RS09460	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GZH91_RS09465	ENOG4107TSN	permease
GZH91_RS09470	ENOG4107R11	Transcriptional regulator
GZH91_RS09480	ENOG4105MRR	Transcriptional regulator (By similarity)
GZH91_RS09485	ENOG4105DPX	Hydrogenase, large subunit
GZH91_RS09505	ENOG4105F71	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GZH91_RS09535	ENOG4107RSS	Hydrogenase accessory protein HypB
GZH91_RS09540	ENOG41081J6	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
GZH91_RS09575	ENOG4108USZ	hydrogenase
GZH91_RS09585	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
GZH91_RS09600	ENOG4105D9G	High-affinity
GZH91_RS09660	ENOG4105KBH	arsR family transcriptional regulator
GZH91_RS09680	ENOG4105KK4	UPF0060 membrane protein
GZH91_RS09725	ENOG4105KT7	mgtC SapB transporter
GZH91_RS09740	ENOG4106NZI	LysR family Transcriptional regulator
GZH91_RS09750	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GZH91_RS09755	ENOG4108RZE	Tetr family transcriptional regulator
GZH91_RS09765	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GZH91_RS09845	ENOG4105DFP	Integrase
GZH91_RS09850	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GZH91_RS09855	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GZH91_RS09865	ENOG4105VDB	UPF0125 protein
GZH91_RS09870	ENOG4108Z1B	Cyclase dehydrase
GZH91_RS09875	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GZH91_RS09880	ENOG4105CV6	ABC transporter, permease
GZH91_RS09885	ENOG4108I0Y	(ABC) transporter
GZH91_RS09890	ENOG4108UJV	acyl-CoA thioesterase i
GZH91_RS09900	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
GZH91_RS09915	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GZH91_RS09920	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GZH91_RS09925	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
GZH91_RS09950	ENOG4108JA2	transcriptioN-repair coupling factor
GZH91_RS09955	ENOG4105EAC	phosphoserine phosphatase
GZH91_RS09960	ENOG4105BZU	Histidine kinase
GZH91_RS09970	ENOG4107RZZ	dna polymerase iii epsilon subunit
GZH91_RS09975	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GZH91_RS09980	ENOG4105D1A	Methyltransferase
GZH91_RS09985	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GZH91_RS09990	ENOG4105E9H	Lytic Murein transglycosylase
GZH91_RS09995	ENOG4108JQ6	ABC transporter
GZH91_RS10000	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GZH91_RS10005	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GZH91_RS10015	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
GZH91_RS10050	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GZH91_RS10065	ENOG4105K70	DNA-binding protein
GZH91_RS10070	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GZH91_RS10075	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GZH91_RS10080	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GZH91_RS10085	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GZH91_RS10095	ENOG4105FE1	phytoene synthase
GZH91_RS10100	ENOG4105FE1	phytoene synthase
GZH91_RS10105	ENOG4107S11	squalene-associated FAD-dependent desaturase
GZH91_RS10110	ENOG4105UBK	short-chain dehydrogenase reductase
GZH91_RS10120	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GZH91_RS10125	ENOG4105C6T	cysteine synthase
GZH91_RS10130	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GZH91_RS10135	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GZH91_RS10140	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GZH91_RS10145	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GZH91_RS10150	ENOG4105CFV	Tetratricopeptide repeat protein
GZH91_RS10160	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GZH91_RS10165	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GZH91_RS10170	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GZH91_RS10180	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
GZH91_RS10185	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GZH91_RS10195	ENOG4108JQ1	Dehydrogenase
GZH91_RS10200	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GZH91_RS10205	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GZH91_RS10210	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GZH91_RS10215	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GZH91_RS10220	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GZH91_RS10240	ENOG4105XIV	Mercuric transport protein, periplasmic component
GZH91_RS10360	ENOG4108ES9	ParB domain protein nuclease
GZH91_RS10415	ENOG4105D07	Signal peptide peptidase, SppA
GZH91_RS10525	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
GZH91_RS10540	ENOG4105C0D	helicase
GZH91_RS10650	ENOG4105DFP	Integrase
GZH91_RS10655	ENOG4105D70	Integrase catalytic subunit
GZH91_RS10660	ENOG4105F5W	AtP-binding protein
GZH91_RS10715	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GZH91_RS10720	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GZH91_RS10725	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GZH91_RS10735	ENOG4105BZ1	(ABC) transporter
GZH91_RS10755	ENOG4105C59	p-type ATPase
GZH91_RS10765	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GZH91_RS10770	ENOG4105F4R	Transcriptional regulator mode
GZH91_RS10805	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GZH91_RS10845	ENOG4105CNG	UPF0061 protein
GZH91_RS10890	ENOG4105C7Z	Conserved Protein
GZH91_RS10905	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GZH91_RS10915	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GZH91_RS10930	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GZH91_RS10935	ENOG4105BZU	Histidine kinase
GZH91_RS10970	ENOG4105F2I	Transposase
GZH91_RS10990	ENOG4105IJJ	transcriptional regulator, crp fnr family
GZH91_RS11010	ENOG4105DG7	nitrate ABC transporter
GZH91_RS11025	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GZH91_RS11045	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GZH91_RS11060	ENOG4107QIZ	NADH dehydrogenase
GZH91_RS11065	ENOG4108IEG	Formate dehydrogenase Alpha subunit
GZH91_RS11070	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GZH91_RS11080	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GZH91_RS11085	ENOG4105F9F	transposase
GZH91_RS11090	ENOG4105F2I	Transposase
GZH91_RS11105	ENOG4105EKT	)-iron permease
GZH91_RS11130	ENOG4107TDF	Formate hydrogenlyase subunit 4
GZH91_RS11140	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GZH91_RS11150	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GZH91_RS11155	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GZH91_RS11190	ENOG4105E2V	Glycosyltransferase 36
GZH91_RS11200	ENOG4105EXG	Transcriptional regulator
GZH91_RS11210	ENOG4105CIS	alcohol dehydrogenase
GZH91_RS11215	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GZH91_RS11220	ENOG4107ZXU	DSBA oxidoreductase
GZH91_RS11235	ENOG4105UYK	outer membrane protein a
GZH91_RS11255	ENOG4107T7U	Sulfatase
GZH91_RS11260	ENOG4108W6C	Dehydrogenase
GZH91_RS11265	ENOG41084CK	capsule polysaccharide
GZH91_RS11270	ENOG4105E12	capsule polysaccharide
GZH91_RS11275	ENOG4105E2K	Glycosyl transferase (Group 1
GZH91_RS11380	ENOG4108AWY	Nucleoside-diphosphate-sugar epimerase
GZH91_RS11390	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GZH91_RS11395	ENOG4105CFG	Acts as a chaperone (By similarity)
GZH91_RS11400	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GZH91_RS11410	ENOG4105F8V	Hydrolase, tatD family
GZH91_RS11420	ENOG4107QRG	dna polymerase iii
GZH91_RS11425	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GZH91_RS11430	ENOG4105HHA	aminodeoxychorismate lyase
GZH91_RS11445	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GZH91_RS11450	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GZH91_RS11455	ENOG4105CHR	reductase
GZH91_RS11460	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GZH91_RS11470	ENOG4105VGS	50s ribosomal protein l32
GZH91_RS11475	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GZH91_RS11480	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GZH91_RS11485	ENOG4107QSA	Oxaloacetate decarboxylase
GZH91_RS11490	ENOG4108UHJ	MAF-like protein
GZH91_RS11505	ENOG4105JVQ	RNA Polymerase
GZH91_RS11515	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GZH91_RS11530	ENOG4105EI2	Pseudouridine synthase
GZH91_RS11535	ENOG4105C03	ribonuclease
GZH91_RS11540	ENOG4105BZU	Histidine kinase
GZH91_RS11545	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GZH91_RS11550	ENOG4105CBS	Chea signal transduction histidine kinase
GZH91_RS11560	ENOG4105YFD	chemotaxis, protein
GZH91_RS11565	ENOG4105BZU	Histidine kinase
GZH91_RS11570	ENOG4105YFD	chemotaxis, protein
GZH91_RS11595	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GZH91_RS11600	ENOG4105CBX	hi0933 family
GZH91_RS11615	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GZH91_RS11620	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GZH91_RS11625	ENOG41080ET	plasmid maintenance system killer protein
GZH91_RS11630	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
GZH91_RS11645	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GZH91_RS11655	ENOG4107QX8	SPFH domain, Band 7 family protein
GZH91_RS11670	ENOG4105KJJ	Uncharacterized ACR, COG1993
GZH91_RS11675	ENOG4107Z6W	Protein CrcB homolog
GZH91_RS11685	ENOG4108UXE	Protein tyrosine phosphatase
GZH91_RS11695	ENOG41085FC	arsR family transcriptional regulator
GZH91_RS11705	ENOG4105F4R	Transcriptional regulator mode
GZH91_RS11710	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
GZH91_RS11715	ENOG4108JUA	Transcriptional regulator
GZH91_RS11730	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZH91_RS11760	ENOG4105C57	major facilitator superfamily
GZH91_RS11780	ENOG4105C59	p-type ATPase
GZH91_RS11795	ENOG4107UWP	Major facilitator superfamily MFS_1
GZH91_RS11820	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
GZH91_RS11835	ENOG4105K59	histidine triad (HIT) protein
GZH91_RS11840	ENOG4107Z6W	Protein CrcB homolog
GZH91_RS11845	ENOG4108ZAF	Molybdopterin
GZH91_RS11850	ENOG4105M00	molybdopterin converting factor, subunit 1
GZH91_RS11855	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GZH91_RS11860	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
GZH91_RS11865	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GZH91_RS11880	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GZH91_RS11885	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GZH91_RS11890	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GZH91_RS11900	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
GZH91_RS11910	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
GZH91_RS11930	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GZH91_RS11935	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GZH91_RS11940	ENOG4105VEQ	Cold shock protein
GZH91_RS11960	ENOG4108R99	pseudouridine synthase
GZH91_RS11970	ENOG4105CHC	glucokinase (EC 2.7.1.2)
GZH91_RS11980	ENOG4105CNG	UPF0061 protein
GZH91_RS11990	ENOG4106RHG	Yeca family
GZH91_RS11995	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GZH91_RS12000	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
GZH91_RS12015	ENOG4105DUM	transcriptional regulator, lysR family
GZH91_RS12035	ENOG4108ZF3	Phosphatase
GZH91_RS12040	ENOG4105D9P	serine threonine protein kinase
GZH91_RS12055	ENOG4105DGU	Histone deacetylase
GZH91_RS12060	ENOG4105FAE	von Willebrand factor, type A
GZH91_RS12085	ENOG4105HA9	of methanol dehydrogenase type
GZH91_RS12090	ENOG4108V0P	LemA family
GZH91_RS12095	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
GZH91_RS12100	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
GZH91_RS12105	ENOG41072GX	Peptidase M22 Glycoprotease
GZH91_RS12120	ENOG4105BZU	Histidine kinase
GZH91_RS12140	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GZH91_RS12145	ENOG4105EMU	Dehydrogenase
GZH91_RS12170	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GZH91_RS12175	ENOG4105BZU	Histidine kinase
GZH91_RS12180	ENOG4105BZU	Histidine kinase
GZH91_RS12190	ENOG4105BZU	Histidine kinase
GZH91_RS12195	ENOG4105E8R	UPF0173 metal-dependent hydrolase
GZH91_RS12200	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
GZH91_RS12210	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GZH91_RS12215	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GZH91_RS12225	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
GZH91_RS12230	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GZH91_RS12240	ENOG4105C59	p-type ATPase
GZH91_RS12250	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
GZH91_RS12270	ENOG4105C58	cytochrome c oxidase accessory protein ccog
GZH91_RS12295	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GZH91_RS12305	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GZH91_RS12315	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GZH91_RS12325	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GZH91_RS12330	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GZH91_RS12335	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GZH91_RS12340	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GZH91_RS12345	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GZH91_RS12385	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GZH91_RS12390	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GZH91_RS12395	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GZH91_RS12400	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GZH91_RS12405	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GZH91_RS12415	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GZH91_RS12420	ENOG4105DZP	Membrane-associated zinc metalloprotease
GZH91_RS12425	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GZH91_RS12430	ENOG4105KNE	Phosphatidate cytidylyltransferase
GZH91_RS12435	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GZH91_RS12440	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GZH91_RS12445	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GZH91_RS12450	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GZH91_RS12455	ENOG4105CE9	30S ribosomal protein S2
GZH91_RS12460	ENOG4105BZ1	(ABC) transporter
GZH91_RS12475	ENOG4105HF0	Membrane
GZH91_RS12480	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GZH91_RS12485	ENOG4105FCD	Major Facilitator
GZH91_RS12500	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZH91_RS12510	ENOG4107WP9	Histidine kinase
GZH91_RS12530	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GZH91_RS12540	ENOG4105E50	uracil-dna glycosylase
GZH91_RS12545	ENOG4105PGM	cation diffusion facilitator family transporter
GZH91_RS12550	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
GZH91_RS12555	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GZH91_RS12580	ENOG4105F2I	Transposase
GZH91_RS12585	ENOG4105BZU	Histidine kinase
GZH91_RS12615	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GZH91_RS12620	ENOG4105C1J	atp-dependent rna helicase
GZH91_RS12625	ENOG4105CI3	gtp-binding protein typa
GZH91_RS12630	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GZH91_RS12635	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GZH91_RS12640	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GZH91_RS12655	ENOG410600T	transposase
GZH91_RS12725	ENOG4106NZI	LysR family Transcriptional regulator
GZH91_RS12730	ENOG4105C8Y	Acetylornithine aminotransferase
GZH91_RS12745	ENOG4105DFA	alanine racemase domain protein
GZH91_RS12750	ENOG4105CSW	GntR family transcriptional regulator
GZH91_RS12755	ENOG41089BK	Glutamine amido-transferase
GZH91_RS12800	ENOG4107QJE	Chromosome Partitioning Protein
GZH91_RS12860	ENOG4105FEQ	ParB domain protein nuclease
GZH91_RS12875	ENOG4108YGG	dna repair protein
GZH91_RS12920	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GZH91_RS12925	ENOG4105CHV	Transcription elongation factor NusA
GZH91_RS12930	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GZH91_RS12935	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GZH91_RS12940	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GZH91_RS12945	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GZH91_RS12950	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GZH91_RS12965	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
GZH91_RS12970	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GZH91_RS12990	ENOG4105DZR	Type I site-specific deoxyribonuclease
GZH91_RS12995	ENOG4107R3N	Filamentation induced by cAMP protein fic
GZH91_RS13005	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
GZH91_RS13015	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GZH91_RS13030	ENOG4105I9Z	UPF0264 protein
GZH91_RS13035	ENOG4105DY8	decarboxylase
GZH91_RS13060	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GZH91_RS13070	ENOG4108P4C	Formaldehyde-activating enzyme
GZH91_RS13085	ENOG41068T5	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT (By similarity)
GZH91_RS13095	ENOG4108M6X	Dehydrogenase
GZH91_RS13110	ENOG4105DCC	Formylmethanofuran dehydrogenase subunit A
GZH91_RS13115	ENOG4105FIE	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) (By similarity)
GZH91_RS13130	ENOG4105EEI	dihydropteroate synthase
GZH91_RS13205	ENOG4105F2I	Transposase
GZH91_RS13215	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
GZH91_RS13225	ENOG4107QIZ	NADH dehydrogenase
GZH91_RS13230	ENOG4108IEG	Formate dehydrogenase Alpha subunit
GZH91_RS13235	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GZH91_RS13245	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GZH91_RS13260	ENOG4107QHF	type ii secretion system protein e
GZH91_RS13265	ENOG4105BZU	Histidine kinase
GZH91_RS13270	ENOG4105CXV	gliding motility protein
GZH91_RS13275	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZH91_RS13280	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GZH91_RS13285	ENOG4105BZU	Histidine kinase
GZH91_RS13290	ENOG4108HU6	Metal dependent phosphohydrolase
GZH91_RS13295	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZH91_RS13300	ENOG4105BZU	Histidine kinase
GZH91_RS13330	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GZH91_RS13335	ENOG4105EFT	decarboxylase
GZH91_RS13340	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
GZH91_RS13345	ENOG4108YZT	Adenosylcobinamide kinase
GZH91_RS13350	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
GZH91_RS13355	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GZH91_RS13370	ENOG4105E4R	Precorrin-3B C17-methyltransferase
GZH91_RS13375	ENOG4108P62	biosynthesis protein (CbiG)
GZH91_RS13380	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
GZH91_RS13405	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GZH91_RS13415	ENOG4105CTK	cobaltochelatase, cobn subunit
GZH91_RS13420	ENOG4105NZG	Ferredoxin
GZH91_RS13440	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
GZH91_RS13445	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
GZH91_RS13460	ENOG4105BZU	Histidine kinase
GZH91_RS13470	ENOG4105BZU	Histidine kinase
GZH91_RS13490	ENOG4105E2V	Glycosyltransferase 36
GZH91_RS13520	ENOG4107QR8	Thioredoxin
GZH91_RS13525	ENOG4107QTF	adenylosuccinate lyase
GZH91_RS13530	ENOG4105C8Q	Methyl-accepting chemotaxis
GZH91_RS13535	ENOG4108V3W	Chemotaxis protein, CheW
GZH91_RS13545	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GZH91_RS13550	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GZH91_RS13555	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GZH91_RS13570	ENOG4105C0X	amino acid
GZH91_RS13595	ENOG4105FB9	CRISPR-associated protein
GZH91_RS13635	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
GZH91_RS13640	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
GZH91_RS13660	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GZH91_RS13675	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GZH91_RS13680	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GZH91_RS13685	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GZH91_RS13700	ENOG4108V1U	phospholipid-binding protein
GZH91_RS13720	ENOG4105CQ7	ATP-dependent helicase
GZH91_RS13725	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
GZH91_RS13735	ENOG4105UYK	outer membrane protein a
GZH91_RS13740	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GZH91_RS13750	ENOG4105DNZ	Alpha Beta Hydrolase
GZH91_RS13760	ENOG4105DJ0	Poly(A) Polymerase
GZH91_RS13765	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GZH91_RS13775	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GZH91_RS13780	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GZH91_RS13785	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
GZH91_RS13805	ENOG4105VZ1	Replication Protein
GZH91_RS13830	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GZH91_RS13835	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GZH91_RS13840	ENOG4105VIE	preprotein translocase, subunit YajC
GZH91_RS13845	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GZH91_RS13850	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GZH91_RS13855	ENOG4107T5V	SNARE associated Golgi
GZH91_RS13880	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GZH91_RS13885	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GZH91_RS13890	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GZH91_RS13895	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GZH91_RS13905	ENOG4105C3F	Signal peptidase i
GZH91_RS13910	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GZH91_RS13920	ENOG4105C0H	protease
GZH91_RS13930	ENOG4105VQK	sigma E regulatory protein, MucB RseB
GZH91_RS13940	ENOG4105EMN	RNA polymerase sigma factor
GZH91_RS13945	ENOG4108IYU	L-aspartate oxidase
GZH91_RS13955	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GZH91_RS13980	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GZH91_RS13995	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GZH91_RS14000	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GZH91_RS14005	ENOG4105CDU	Replicative dna helicase
GZH91_RS14010	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GZH91_RS14015	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GZH91_RS14025	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GZH91_RS14040	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GZH91_RS14045	ENOG4105CTB	Polyprenyl synthetase
GZH91_RS14050	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GZH91_RS14055	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
GZH91_RS14075	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GZH91_RS14090	ENOG4107RIQ	Sulfate adenylate transferase
GZH91_RS14115	ENOG4105FAE	von Willebrand factor, type A
GZH91_RS14125	ENOG4105BZU	Histidine kinase
GZH91_RS14130	ENOG4105F2I	Transposase
GZH91_RS14135	ENOG4105BZU	Histidine kinase
GZH91_RS14155	ENOG4105E18	UPF0276 protein
GZH91_RS14190	ENOG4108WQI	RNA Polymerase
GZH91_RS14235	ENOG4107QIV	Cytochrome c biogenesis protein
GZH91_RS14255	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
GZH91_RS14260	ENOG4105BZS	acriflavin resistance protein
GZH91_RS14280	ENOG4108J5G	6-phosphogluconate dehydrogenase
GZH91_RS14285	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GZH91_RS14310	ENOG4108WQI	RNA Polymerase
GZH91_RS14315	ENOG4108ESY	Metal dependent phosphohydrolase
GZH91_RS14325	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
GZH91_RS14335	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GZH91_RS14340	ENOG4105BZU	Histidine kinase
GZH91_RS14355	ENOG4105XMH	SpoVT AbrB domain protein
GZH91_RS14360	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
GZH91_RS14390	ENOG4105D4P	Coproporphyrinogen iii oxidase
GZH91_RS14395	ENOG4105CX6	glutaminyL-tRNA synthetase
GZH91_RS14400	ENOG4105D3R	alkyl hydroperoxide reductase
GZH91_RS14410	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GZH91_RS14415	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
GZH91_RS14420	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GZH91_RS14430	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GZH91_RS14460	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GZH91_RS14470	ENOG4105BZM	domain protein
GZH91_RS14475	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GZH91_RS14480	ENOG4105D7N	magnesium and cobalt transport protein CorA
GZH91_RS14485	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GZH91_RS14490	ENOG4105BZU	Histidine kinase
GZH91_RS14530	ENOG4105W3H	MtN3 and saliva related transmembrane protein
GZH91_RS14545	ENOG4105CXN	decarboxylase
GZH91_RS14550	ENOG4105DHP	deoxycytidine triphosphate deaminase
GZH91_RS14575	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GZH91_RS14585	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
GZH91_RS14595	ENOG4105I7M	spermidine synthase
GZH91_RS14600	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GZH91_RS14605	ENOG4105E4C	Lytic transglycosylase catalytic
GZH91_RS14625	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GZH91_RS14630	ENOG4108IJ0	Aspartate ammonia-lyase
GZH91_RS14655	ENOG4105CS1	NAD(P)H quinone oxidoreductase
GZH91_RS14675	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GZH91_RS14680	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
GZH91_RS14685	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
GZH91_RS14690	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GZH91_RS14695	ENOG4108ZP8	Acetolactate synthase small subunit
GZH91_RS14700	ENOG4105C7K	acetolactate synthase
GZH91_RS14705	ENOG4105C98	muts2 protein
GZH91_RS14725	ENOG4105VQU	rdd domain containing protein
GZH91_RS14735	ENOG4108M8S	permease YjgP YjgQ family protein
GZH91_RS14740	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GZH91_RS14745	ENOG4105MYG	DNA polymerase iii, chi subunit
GZH91_RS14755	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GZH91_RS14810	ENOG4105PHD	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GZH91_RS14820	ENOG4105RQ5	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GZH91_RS14825	ENOG41086B8	CoB-CoM heterodisulfide reductase
GZH91_RS14840	ENOG4105EWK	phytoene
GZH91_RS14855	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
GZH91_RS14860	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GZH91_RS14865	ENOG4105C72	UPF0176 protein
GZH91_RS14875	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GZH91_RS14880	ENOG4105DB1	molybdopterin oxidoreductase
GZH91_RS14915	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GZH91_RS14950	ENOG4107TPS	domain protein
GZH91_RS14955	ENOG41080HT	Transcriptional regulator, arsr family
GZH91_RS14965	ENOG4105BZU	Histidine kinase
GZH91_RS14970	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GZH91_RS14975	ENOG4105ERG	peptidase m48, ste24p
GZH91_RS14995	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
GZH91_RS15005	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GZH91_RS15050	ENOG4107QHF	type ii secretion system protein e
GZH91_RS15055	ENOG4105D7Q	type ii secretion system
GZH91_RS15115	ENOG4105F2I	Transposase
GZH91_RS15130	ENOG4105C2X	Arabinose 5-phosphate isomerase
GZH91_RS15135	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
GZH91_RS15150	ENOG4108IUZ	ABC transporter
GZH91_RS15155	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GZH91_RS15160	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GZH91_RS15165	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GZH91_RS15170	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
GZH91_RS15175	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GZH91_RS15190	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GZH91_RS15200	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GZH91_RS15210	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GZH91_RS15225	ENOG4105C4R	Atp-dependent dna helicase
GZH91_RS15230	ENOG4107YZP	Rhodanese domain protein
GZH91_RS15240	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
GZH91_RS15245	ENOG4105DQ4	alcohol dehydrogenase
GZH91_RS15255	ENOG4105C8T	Leucyl-tRNA synthetase
GZH91_RS15260	ENOG4108U2H	Rare lipoprotein B
GZH91_RS15275	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GZH91_RS15280	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GZH91_RS15285	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GZH91_RS15295	ENOG4108Z03	MAF-like protein
GZH91_RS15300	ENOG4105C03	ribonuclease
GZH91_RS15305	ENOG410890F	Dynamin family
GZH91_RS15310	ENOG4105VZ9	UPF0235 protein
GZH91_RS15315	ENOG4108VIA	integral membrane protein
GZH91_RS15320	ENOG4105II7	pyrroline-5-carboxylate reductase
GZH91_RS15325	ENOG4105DFA	alanine racemase domain protein
GZH91_RS15330	ENOG4105CZX	twitching motility protein
GZH91_RS15335	ENOG4105CZX	twitching motility protein
GZH91_RS15340	ENOG4105BZU	Histidine kinase
GZH91_RS15345	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GZH91_RS15350	ENOG4108YXA	Membrane
GZH91_RS15365	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GZH91_RS15380	ENOG4105CQB	FAD linked oxidase domain protein
GZH91_RS15395	ENOG4105BZU	Histidine kinase
GZH91_RS15400	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GZH91_RS15405	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GZH91_RS15415	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GZH91_RS15420	ENOG4108IA2	Sodium pantothenate symporter
GZH91_RS15430	ENOG4107RIQ	Sulfate adenylate transferase
GZH91_RS15455	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GZH91_RS15460	ENOG4105E4G	Type IV pilus
GZH91_RS15485	ENOG4108JQC	penicillin-binding protein 1A
GZH91_RS15500	ENOG4105BZU	Histidine kinase
GZH91_RS15505	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZH91_RS15540	ENOG4105D52	delta-aminolevulinic acid dehydratase
GZH91_RS15545	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GZH91_RS15555	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
GZH91_RS15560	ENOG4105CRE	cytochrome C
GZH91_RS15565	ENOG4105F2I	Transposase
GZH91_RS15585	ENOG4105F2I	Transposase
GZH91_RS15605	ENOG4105F2I	Transposase
GZH91_RS15610	ENOG4107QRT	dEAD DEAH box helicase
GZH91_RS15620	ENOG4105CUV	Homoserine Kinase
GZH91_RS15630	ENOG4108URH	decarboxylase
GZH91_RS15635	ENOG4105C2M	dna polymerase I
GZH91_RS15640	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GZH91_RS15645	ENOG4105D60	lipoprotein releasing system transmembrane protein
GZH91_RS15655	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GZH91_RS15665	ENOG4105ERG	peptidase m48, ste24p
GZH91_RS15670	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GZH91_RS15675	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GZH91_RS15680	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GZH91_RS15685	ENOG4105C12	Phosphoribosylglycinamide synthetase
GZH91_RS15690	ENOG4107XQ8	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GZH91_RS15695	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GZH91_RS15705	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GZH91_RS15710	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GZH91_RS15715	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GZH91_RS15730	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
GZH91_RS15755	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GZH91_RS15760	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GZH91_RS15770	ENOG4105VCQ	rubredoxin
GZH91_RS15775	ENOG4108UNF	response regulator
GZH91_RS15780	ENOG4105M3Z	response regulator
GZH91_RS15790	ENOG4105C8Q	Methyl-accepting chemotaxis
GZH91_RS15795	ENOG4105CBS	Chea signal transduction histidine kinase
GZH91_RS15800	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GZH91_RS15805	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GZH91_RS15810	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GZH91_RS15820	ENOG4105DFG	type I secretion outer membrane protein
GZH91_RS15825	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GZH91_RS15850	ENOG4108MX3	Polysaccharide Biosynthesis Protein
GZH91_RS15855	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
GZH91_RS15860	ENOG4107XZA	Glycosyl transferase family 2
GZH91_RS15905	ENOG4105ESV	Glycosyl transferase, family 4
GZH91_RS15955	ENOG4107RGC	Glycosyl transferase, family 2
GZH91_RS15965	ENOG4105EY8	ABC transporter
GZH91_RS16020	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
GZH91_RS16035	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GZH91_RS16065	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GZH91_RS16070	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GZH91_RS16075	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GZH91_RS16080	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GZH91_RS16085	ENOG4105CPF	Cell wall formation (By similarity)
GZH91_RS16090	ENOG4105D4A	Cell wall formation (By similarity)
GZH91_RS16095	ENOG4105DFU	Cell wall formation (By similarity)
GZH91_RS16100	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GZH91_RS16105	ENOG4105CNI	cell division protein FtsW
GZH91_RS16110	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GZH91_RS16115	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GZH91_RS16120	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GZH91_RS16125	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GZH91_RS16130	ENOG4105CJN	penicillin-binding protein
GZH91_RS16140	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GZH91_RS16145	ENOG4108V6E	Cell division protein mraZ
GZH91_RS16150	ENOG4108RRZ	Transcription elongation factor GreB
GZH91_RS16170	ENOG4105BZU	Histidine kinase
GZH91_RS16175	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GZH91_RS16195	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GZH91_RS16210	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
GZH91_RS16240	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GZH91_RS16245	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GZH91_RS16260	ENOG4105EKE	dihydroorotase
GZH91_RS16265	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GZH91_RS16270	ENOG41082RQ	UPF0102 protein
GZH91_RS16275	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GZH91_RS16280	ENOG4105W4M	Transport-associated protein
GZH91_RS16285	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GZH91_RS16290	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GZH91_RS16385	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GZH91_RS16390	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GZH91_RS16410	ENOG4105BZU	Histidine kinase
GZH91_RS16420	ENOG41061WM	D-Alanyl-D-Alanine
GZH91_RS16430	ENOG4107258	Transcriptional regulator
GZH91_RS16445	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
GZH91_RS16460	ENOG4105C0Z	ABC transporter
GZH91_RS16465	ENOG4108IV0	ABC, transporter
GZH91_RS16480	ENOG4105C26	Dehydrogenase
GZH91_RS16490	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GZH91_RS16495	ENOG4105C5I	Dehydrogenase
GZH91_RS16510	ENOG4105CQB	FAD linked oxidase domain protein
GZH91_RS16515	ENOG4105EU8	FAD linked oxidase domain protein
GZH91_RS16520	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GZH91_RS16525	ENOG4105CBC	glutamate synthase
GZH91_RS16530	ENOG4105BZ8	glutamate synthase
GZH91_RS16535	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GZH91_RS16540	ENOG4105C25	Primosomal protein n'
GZH91_RS16545	ENOG4105C75	arginyL-tRNA synthetase
GZH91_RS16565	ENOG4105WH1	Two component transcriptional regulator luxr family
GZH91_RS16575	ENOG4105M6F	mutator MutT protein
GZH91_RS16585	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
GZH91_RS16590	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GZH91_RS16600	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GZH91_RS16635	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GZH91_RS16645	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GZH91_RS16650	ENOG4108IV0	ABC, transporter
GZH91_RS16655	ENOG4105C0Z	ABC transporter
GZH91_RS16660	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
GZH91_RS16665	ENOG4105C32	Amino acid ABC transporter (Permease)
GZH91_RS16675	ENOG4105W2Z	cytochrome C, class I
GZH91_RS16685	ENOG4105C01	Dihydroxy-acid dehydratase
GZH91_RS16690	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GZH91_RS16700	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GZH91_RS16705	ENOG4105C9A	Phoh family
GZH91_RS16710	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GZH91_RS16715	ENOG4108JU5	Magnesium and cobalt efflux protein
GZH91_RS16720	ENOG4106RE7	Cytochrome
GZH91_RS16730	ENOG4105D2N	Aldolase
GZH91_RS16735	ENOG4105CA9	Pyruvate kinase
GZH91_RS16740	ENOG4105BZA	Phosphoglycerate kinase
GZH91_RS16745	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GZH91_RS16750	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GZH91_RS16755	ENOG4105ECY	inositol monophosphatase
GZH91_RS16765	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GZH91_RS16770	ENOG4108EKC	n-acetylglutamate synthase
GZH91_RS16780	ENOG4105BZU	Histidine kinase
GZH91_RS16785	ENOG4105C5H	ABC transporter
GZH91_RS16790	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GZH91_RS16810	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GZH91_RS16815	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GZH91_RS16825	ENOG4105D2N	Aldolase
GZH91_RS16850	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
GZH91_RS16865	ENOG4105KNY	Microcompartments protein
GZH91_RS16870	ENOG4105KNY	Microcompartments protein
GZH91_RS16875	ENOG4105KNY	Microcompartments protein
GZH91_RS16900	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
GZH91_RS16905	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
GZH91_RS16910	ENOG4105DUM	transcriptional regulator, lysR family
GZH91_RS16920	ENOG4105EVH	UPF0753 protein
GZH91_RS16935	ENOG4105IPI	Membrane
GZH91_RS16945	ENOG4105DU1	integral membrane protein, terc
GZH91_RS16950	ENOG4105D0M	Protease HtpX homolog
GZH91_RS16960	ENOG4108MN8	Membrane
GZH91_RS16965	ENOG41063Z6	transcriptional regulator, lysR family
GZH91_RS16970	ENOG4105FAE	von Willebrand factor, type A
GZH91_RS16980	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
GZH91_RS16985	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
GZH91_RS16990	ENOG4105DUM	transcriptional regulator, lysR family
GZH91_RS17000	ENOG4105ECF	c-methyltransferase
GZH91_RS17005	ENOG41076E6	Uroporphyrinogen-III Synthase
GZH91_RS17010	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GZH91_RS17020	ENOG4108NEV	two component transcriptional regulator, LytTR family
GZH91_RS17025	ENOG4108HRK	Histidine kinase
GZH91_RS17030	ENOG4105CH7	arginosuccinase
GZH91_RS17040	ENOG4105BZU	Histidine kinase
GZH91_RS17060	ENOG4105XQ6	frataxin-like protein
GZH91_RS17070	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GZH91_RS17080	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
GZH91_RS17085	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
GZH91_RS17090	ENOG4105BZU	Histidine kinase
GZH91_RS17095	ENOG4105BZU	Histidine kinase
GZH91_RS17105	ENOG41080RH	Thioredoxin
GZH91_RS17120	ENOG4107QZF	nitrite reductase NADPH large subunit
GZH91_RS17125	ENOG4105VCQ	rubredoxin
GZH91_RS17145	ENOG4105UYK	outer membrane protein a
GZH91_RS17155	ENOG4105CH6	catalase
GZH91_RS17160	ENOG4105DHQ	Histidine kinase
GZH91_RS17165	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GZH91_RS17180	ENOG4105CJ1	ABC, transporter
GZH91_RS17210	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
GZH91_RS17225	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
GZH91_RS17240	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GZH91_RS17250	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GZH91_RS17255	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GZH91_RS17260	ENOG4105K63	Thioredoxin
GZH91_RS17265	ENOG4108Z4U	Ferredoxin
GZH91_RS17275	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
GZH91_RS17285	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GZH91_RS17305	ENOG4105VRT	cytoplasmic protein
GZH91_RS17320	ENOG4107MBR	17 kDa surface antigen
GZH91_RS17325	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GZH91_RS17330	ENOG4108MTB	glycosyl transferase family
GZH91_RS17335	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GZH91_RS17340	ENOG4108IFG	nitrite reductase, (NAD(P)H)
GZH91_RS17365	ENOG4105F2I	Transposase
GZH91_RS17400	ENOG4105D7T	ABC transporter
GZH91_RS17410	ENOG4105DZ0	fad dependent oxidoreductase
GZH91_RS17415	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
GZH91_RS17420	ENOG4107Y70	Heat shock protein
GZH91_RS17430	ENOG41062IR	nudix hydrolase
GZH91_RS17435	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GZH91_RS17440	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GZH91_RS17445	ENOG4105BZU	Histidine kinase
GZH91_RS17450	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GZH91_RS17455	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GZH91_RS17460	ENOG4105W5Q	DNA repair protein (RadC
GZH91_RS17465	ENOG4105KDC	50s ribosomal protein l28
GZH91_RS17470	ENOG4105W0E	50S ribosomal protein L33
GZH91_RS17480	ENOG4105EGS	Mechanosensitive ion channel
GZH91_RS17485	ENOG4105N82	Endonuclease
GZH91_RS17505	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
GZH91_RS17510	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GZH91_RS17515	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GZH91_RS17525	ENOG4107TDF	Formate hydrogenlyase subunit 4
GZH91_RS17530	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GZH91_RS17540	ENOG4108EX3	reductase
GZH91_RS17550	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GZH91_RS17555	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GZH91_RS17560	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GZH91_RS17565	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GZH91_RS17570	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GZH91_RS17575	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GZH91_RS17580	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GZH91_RS17585	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GZH91_RS17590	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
GZH91_RS17600	ENOG4105FA0	parb-like partition protein
GZH91_RS17605	ENOG4107QJE	Chromosome Partitioning Protein
GZH91_RS17610	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GZH91_RS17615	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GZH91_RS17620	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GZH91_RS17625	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GZH91_RS17630	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GZH91_RS17635	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GZH91_RS17640	ENOG4105VG0	50S ribosomal protein l34