locus-tag	class	description
GZH91_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GZH91_RS00010	COG0592	DNA-directed DNA polymerase activity
GZH91_RS00020	COG1832	CoA-binding protein
GZH91_RS00025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GZH91_RS00040	COG0523	cobalamin synthesis protein
GZH91_RS00050	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GZH91_RS00055	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GZH91_RS00060	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GZH91_RS00080	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GZH91_RS00085	COG4191	Histidine kinase
GZH91_RS00100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GZH91_RS00105	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GZH91_RS00115	COG0174	glutamine synthetase
GZH91_RS00125	COG3852	Histidine kinase
GZH91_RS00145	COG0509	glycine decarboxylation via glycine cleavage system
GZH91_RS00160	COG0708	Exodeoxyribonuclease III
GZH91_RS00175	COG4451	ribulose bisphosphate carboxylase, small
GZH91_RS00180	COG1850	ribulose-bisphosphate carboxylase activity
GZH91_RS00185	COG0583	DNA-binding transcription factor activity
GZH91_RS00195	COG0339	signal peptide processing
GZH91_RS00200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GZH91_RS00205	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GZH91_RS00210	COG0540	Belongs to the ATCase OTCase family
GZH91_RS00215	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GZH91_RS00220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GZH91_RS00225	COG1678	Uncharacterized ACR, COG1678
GZH91_RS00230	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GZH91_RS00240	COG0557	exoribonuclease II activity
GZH91_RS00245	COG3150	esterase
GZH91_RS00280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GZH91_RS00285	COG1116	anion transmembrane transporter activity
GZH91_RS00285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GZH91_RS00290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GZH91_RS00295	COG1116	anion transmembrane transporter activity
GZH91_RS00300	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GZH91_RS00315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GZH91_RS00360	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GZH91_RS00360	COG1672	PFAM Archaeal ATPase
GZH91_RS00370	COG0646	methionine synthase
GZH91_RS00370	COG1410	methionine synthase
GZH91_RS00380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GZH91_RS00385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GZH91_RS00390	COG1950	PFAM Membrane protein of
GZH91_RS00395	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GZH91_RS00400	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GZH91_RS00410	COG1560	Kdo2-lipid A biosynthetic process
GZH91_RS00420	COG5002	protein histidine kinase activity
GZH91_RS00425	COG0745	RESPONSE REGULATOR receiver
GZH91_RS00450	COG2922	Belongs to the Smg family
GZH91_RS00455	COG0758	DNA mediated transformation
GZH91_RS00465	COG0242	peptide deformylase activity
GZH91_RS00470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GZH91_RS00500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GZH91_RS00510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GZH91_RS00525	COG0004	ammonium transporteR
GZH91_RS00530	COG0347	Belongs to the P(II) protein family
GZH91_RS00545	COG0606	chelatase, subunit chli
GZH91_RS00550	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GZH91_RS00555	COG0321	lipoyl(octanoyl) transferase activity
GZH91_RS00560	COG2921	Belongs to the UPF0250 family
GZH91_RS00565	COG1686	Belongs to the peptidase S11 family
GZH91_RS00575	COG0772	Belongs to the SEDS family
GZH91_RS00580	COG0768	penicillin binding
GZH91_RS00585	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GZH91_RS00595	COG1077	Cell shape determining protein MreB Mrl
GZH91_RS00600	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GZH91_RS00605	COG0154	amidase activity
GZH91_RS00610	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GZH91_RS00615	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GZH91_RS00635	COG5002	protein histidine kinase activity
GZH91_RS00640	COG0745	RESPONSE REGULATOR receiver
GZH91_RS00645	COG1595	DNA-templated transcription, initiation
GZH91_RS00650	COG1278	Cold shock
GZH91_RS00690	COG0625	glutathione transferase activity
GZH91_RS00705	COG0569	domain protein
GZH91_RS00710	COG2204	response regulator
GZH91_RS00715	COG5000	phosphorelay sensor kinase activity
GZH91_RS00725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GZH91_RS00725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GZH91_RS00735	COG2814	Major facilitator Superfamily
GZH91_RS00740	COG0708	Exodeoxyribonuclease III
GZH91_RS00745	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GZH91_RS00765	COG4232	protein-disulfide reductase activity
GZH91_RS00770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GZH91_RS00775	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GZH91_RS00780	COG0511	ligase activity, forming carbon-carbon bonds
GZH91_RS00785	COG0439	Biotin carboxylase
GZH91_RS00790	COG2264	protein methyltransferase activity
GZH91_RS00805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GZH91_RS00810	COG0509	glycine decarboxylation via glycine cleavage system
GZH91_RS00815	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GZH91_RS00820	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GZH91_RS00825	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GZH91_RS00855	COG2132	Multicopper oxidase
GZH91_RS00890	COG0671	phosphoesterase, PA-phosphatase related
GZH91_RS00900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GZH91_RS00920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GZH91_RS00955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GZH91_RS00960	COG3001	Fructosamine kinase
GZH91_RS01000	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GZH91_RS01005	COG0628	permease
GZH91_RS01010	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GZH91_RS01020	COG0730	response to heat
GZH91_RS01055	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GZH91_RS01065	COG3220	belongs to the UPF0276 family
GZH91_RS01075	COG2239	Acts as a magnesium transporter
GZH91_RS01080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GZH91_RS01090	COG1132	(ABC) transporter
GZH91_RS01095	COG0037	tRNA processing
GZH91_RS01105	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GZH91_RS01135	COG2945	thiolester hydrolase activity
GZH91_RS01150	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GZH91_RS01155	COG1596	polysaccharide export
GZH91_RS01165	COG0489	protein tyrosine kinase activity
GZH91_RS01175	COG3409	Peptidoglycan-binding domain 1 protein
GZH91_RS01175	COG3267	Type II secretory pathway component ExeA
GZH91_RS01205	COG0438	transferase activity, transferring glycosyl groups
GZH91_RS01210	COG0367	asparagine synthase
GZH91_RS01220	COG0438	transferase activity, transferring glycosyl groups
GZH91_RS01225	COG0438	transferase activity, transferring glycosyl groups
GZH91_RS01255	COG1216	Glycosyl transferase, family 2
GZH91_RS01255	COG1442	glycosyl transferase family 8
GZH91_RS01260	COG3039	Transposase
GZH91_RS01265	COG0438	transferase activity, transferring glycosyl groups
GZH91_RS01275	COG3119	arylsulfatase activity
GZH91_RS01285	COG1215	transferase activity, transferring glycosyl groups
GZH91_RS01295	COG1216	Glycosyl transferase, family 2
GZH91_RS01300	COG0726	polysaccharide deacetylase
GZH91_RS01305	COG3754	Rhamnan synthesis protein F
GZH91_RS01310	COG2244	polysaccharide biosynthetic process
GZH91_RS01315	COG1216	Glycosyl transferase, family 2
GZH91_RS01325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GZH91_RS01330	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GZH91_RS01340	COG1902	pentaerythritol trinitrate reductase activity
GZH91_RS01345	COG1979	alcohol dehydrogenase
GZH91_RS01350	COG1040	competence protein
GZH91_RS01360	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GZH91_RS01365	COG0156	8-amino-7-oxononanoate synthase activity
GZH91_RS01370	COG2267	carboxylic ester hydrolase activity
GZH91_RS01375	COG2226	methyltransferase
GZH91_RS01380	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GZH91_RS01395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GZH91_RS01400	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GZH91_RS01430	COG0109	protoheme IX farnesyltransferase activity
GZH91_RS01435	COG1999	signal sequence binding
GZH91_RS01440	COG3278	Belongs to the heme-copper respiratory oxidase family
GZH91_RS01455	COG2010	Cytochrome c
GZH91_RS01460	COG0348	domain, Protein
GZH91_RS01470	COG2217	Heavy metal translocating P-type atpase
GZH91_RS01490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GZH91_RS01495	COG2177	Part of the ABC transporter FtsEX involved in
GZH91_RS01500	COG2884	Cell division ATP-binding protein ftsE
GZH91_RS01510	COG0612	Peptidase, M16
GZH91_RS01515	COG0612	Peptidase, M16
GZH91_RS01520	COG0742	ribosomal rna small subunit methyltransferase
GZH91_RS01525	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GZH91_RS01530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GZH91_RS01540	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GZH91_RS01570	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GZH91_RS01575	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GZH91_RS01580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GZH91_RS01585	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GZH91_RS01595	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GZH91_RS01605	COG0006	proline dipeptidase activity
GZH91_RS01610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GZH91_RS01615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GZH91_RS01630	COG0134	indole-3-glycerol-phosphate synthase activity
GZH91_RS01635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GZH91_RS01740	COG3916	Acyl-homoserine-lactone synthase
GZH91_RS01750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GZH91_RS01755	COG2813	Specifically methylates the guanine in position
GZH91_RS01755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GZH91_RS01775	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GZH91_RS01780	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GZH91_RS01785	COG3958	Transketolase
GZH91_RS01795	COG0028	Belongs to the TPP enzyme family
GZH91_RS01795	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
GZH91_RS01805	COG1181	Belongs to the D-alanine--D-alanine ligase family
GZH91_RS01860	COG2132	Multicopper oxidase
GZH91_RS01865	COG0745	RESPONSE REGULATOR receiver
GZH91_RS01905	COG1968	undecaprenyl-diphosphatase activity
GZH91_RS01920	COG1815	bacterial-type flagellum-dependent cell motility
GZH91_RS01935	COG1285	pathogenesis
GZH91_RS01980	COG1742	UPF0060 membrane protein
GZH91_RS02025	COG0640	Transcriptional regulator
GZH91_RS02030	COG0672	)-iron permease
GZH91_RS02095	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GZH91_RS02155	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GZH91_RS02165	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GZH91_RS02190	COG0776	regulation of translation
GZH91_RS02215	COG2132	Multicopper oxidase
GZH91_RS02220	COG1815	bacterial-type flagellum-dependent cell motility
GZH91_RS02260	COG0477	Major facilitator Superfamily
GZH91_RS02265	COG2217	Heavy metal translocating P-type atpase
GZH91_RS02290	COG2076	Multidrug Resistance protein
GZH91_RS02305	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GZH91_RS02310	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GZH91_RS02350	COG0723	plastoquinol--plastocyanin reductase activity
GZH91_RS02380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GZH91_RS02380	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GZH91_RS02455	COG3245	cytochrome
GZH91_RS02515	COG2885	chlorophyll binding
GZH91_RS02545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GZH91_RS02625	COG0582	viral genome integration into host DNA
GZH91_RS02650	COG2226	methyltransferase
GZH91_RS02660	COG0546	phosphoglycolate phosphatase activity
GZH91_RS02665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GZH91_RS02670	COG2967	ApaG domain
GZH91_RS02680	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GZH91_RS02695	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GZH91_RS02725	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GZH91_RS02735	COG1765	OsmC-like protein
GZH91_RS02740	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GZH91_RS02745	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GZH91_RS02750	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GZH91_RS02755	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GZH91_RS02760	COG0316	Belongs to the HesB IscA family
GZH91_RS02765	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GZH91_RS02775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GZH91_RS02805	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GZH91_RS02810	COG0475	glutathione-regulated potassium exporter activity
GZH91_RS02815	COG0084	hydrolase, TatD family'
GZH91_RS02820	COG0668	transmembrane transport
GZH91_RS02825	COG0438	transferase activity, transferring glycosyl groups
GZH91_RS02830	COG0438	transferase activity, transferring glycosyl groups
GZH91_RS02865	COG2022	thiamine diphosphate biosynthetic process
GZH91_RS02870	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GZH91_RS02885	COG0493	'glutamate synthase
GZH91_RS02905	COG2719	SpoVR family
GZH91_RS02910	COG2718	Belongs to the UPF0229 family
GZH91_RS02915	COG2766	serine protein kinase
GZH91_RS02920	COG0302	gtp cyclohydrolase
GZH91_RS02945	COG3647	Membrane
GZH91_RS02950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GZH91_RS02965	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GZH91_RS02970	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GZH91_RS02980	COG1357	PFAM Pentapeptide repeats (8 copies)
GZH91_RS02980	COG0515	serine threonine protein kinase
GZH91_RS02985	COG1561	YicC-like family, N-terminal region
GZH91_RS02990	COG0194	GDP metabolic process
GZH91_RS02995	COG1758	RNA polymerase activity
GZH91_RS03000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GZH91_RS03010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GZH91_RS03020	COG3161	chorismate lyase activity
GZH91_RS03025	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GZH91_RS03035	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GZH91_RS03085	COG1595	DNA-templated transcription, initiation
GZH91_RS03095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GZH91_RS03105	COG0189	ligase activity
GZH91_RS03125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GZH91_RS03145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GZH91_RS03155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GZH91_RS03170	COG0640	Transcriptional regulator
GZH91_RS03175	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GZH91_RS03180	COG4942	peptidase
GZH91_RS03185	COG0793	Belongs to the peptidase S41A family
GZH91_RS03195	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GZH91_RS03205	COG1271	oxidase subunit
GZH91_RS03210	COG1294	oxidase, subunit
GZH91_RS03225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GZH91_RS03230	COG0713	ATP synthesis coupled electron transport
GZH91_RS03240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GZH91_RS03245	COG0649	NAD binding
GZH91_RS03255	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GZH91_RS03280	COG1610	YqeY-like protein
GZH91_RS03285	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GZH91_RS03290	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GZH91_RS03300	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GZH91_RS03305	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GZH91_RS03320	COG0335	large ribosomal subunit rRNA binding
GZH91_RS03325	COG0336	Belongs to the RNA methyltransferase TrmD family
GZH91_RS03330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GZH91_RS03335	COG0228	four-way junction DNA binding
GZH91_RS03340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GZH91_RS03345	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GZH91_RS03350	COG4536	flavin adenine dinucleotide binding
GZH91_RS03365	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GZH91_RS03370	COG0237	dephospho-CoA kinase activity
GZH91_RS03375	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GZH91_RS03395	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GZH91_RS03400	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GZH91_RS03405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GZH91_RS03415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GZH91_RS03420	COG0617	tRNA 3'-terminal CCA addition
GZH91_RS03435	COG0745	RESPONSE REGULATOR receiver
GZH91_RS03450	COG0752	glycyl-tRNA synthetase alpha subunit
GZH91_RS03455	COG0751	glycine-tRNA ligase activity
GZH91_RS03465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GZH91_RS03485	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GZH91_RS03490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GZH91_RS03500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GZH91_RS03505	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GZH91_RS03510	COG0193	aminoacyl-tRNA hydrolase activity
GZH91_RS03515	COG0012	GTP binding
GZH91_RS03535	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GZH91_RS03545	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GZH91_RS03555	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GZH91_RS03560	COG0081	regulation of translation
GZH91_RS03565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GZH91_RS03570	COG0222	ribosome binding
GZH91_RS03575	COG0085	RNA polymerase activity
GZH91_RS03580	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GZH91_RS03585	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GZH91_RS03590	COG0049	tRNA binding
GZH91_RS03595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GZH91_RS03600	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GZH91_RS03605	COG0051	transcription antitermination factor activity, RNA binding
GZH91_RS03610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GZH91_RS03615	COG0088	Forms part of the polypeptide exit tunnel
GZH91_RS03620	COG0089	rRNA binding
GZH91_RS03625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GZH91_RS03635	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GZH91_RS03640	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GZH91_RS03645	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GZH91_RS03650	COG0255	Belongs to the universal ribosomal protein uL29 family
GZH91_RS03655	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GZH91_RS03660	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GZH91_RS03665	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GZH91_RS03670	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GZH91_RS03675	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GZH91_RS03680	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GZH91_RS03685	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GZH91_RS03690	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GZH91_RS03695	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GZH91_RS03700	COG1841	ribosomal large subunit assembly
GZH91_RS03705	COG0200	Binds to the 23S rRNA
GZH91_RS03710	COG0201	protein transport
GZH91_RS03715	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GZH91_RS03720	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GZH91_RS03725	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GZH91_RS03730	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GZH91_RS03735	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GZH91_RS03740	COG0202	RNA polymerase activity
GZH91_RS03745	COG0203	ribosomal protein L17
GZH91_RS03765	COG2814	Major facilitator Superfamily
GZH91_RS03770	COG0629	single-stranded DNA binding
GZH91_RS03775	COG0318	PFAM AMP-dependent synthetase and ligase
GZH91_RS03775	COG0204	Acyl-transferase
GZH91_RS03795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GZH91_RS03805	COG0494	nUDIX hydrolase
GZH91_RS03810	COG2200	EAL domain
GZH91_RS03815	COG3568	Endonuclease Exonuclease Phosphatase
GZH91_RS03820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GZH91_RS03850	COG0217	transcriptional regulatory protein
GZH91_RS03855	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GZH91_RS03860	COG0632	four-way junction helicase activity
GZH91_RS03865	COG2255	four-way junction helicase activity
GZH91_RS03870	COG0824	Thioesterase
GZH91_RS03890	COG0823	Involved in the tonB-independent uptake of proteins
GZH91_RS03910	COG0602	queuosine metabolic process
GZH91_RS03915	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GZH91_RS03925	COG3028	Belongs to the UPF0307 family
GZH91_RS03930	COG0312	modulator of DNA gyrase
GZH91_RS03935	COG1944	ATP diphosphatase activity
GZH91_RS03960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GZH91_RS03960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GZH91_RS03970	COG2855	membrane
GZH91_RS04005	COG0438	transferase activity, transferring glycosyl groups
GZH91_RS04010	COG2137	regulation of response to DNA damage stimulus
GZH91_RS04015	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GZH91_RS04020	COG1546	Belongs to the CinA family
GZH91_RS04025	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GZH91_RS04030	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GZH91_RS04035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GZH91_RS04040	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GZH91_RS04055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GZH91_RS04055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GZH91_RS04060	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GZH91_RS04065	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GZH91_RS04075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GZH91_RS04090	COG2346	COG2346, Truncated hemoglobins
GZH91_RS04110	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GZH91_RS04115	COG0700	Nucleoside recognition
GZH91_RS04130	COG3025	triphosphatase activity
GZH91_RS04135	COG2062	phosphohistidine phosphatase, SixA
GZH91_RS04140	COG0745	RESPONSE REGULATOR receiver
GZH91_RS04145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GZH91_RS04150	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GZH91_RS04155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GZH91_RS04160	COG2814	Major facilitator Superfamily
GZH91_RS04165	COG0513	Belongs to the DEAD box helicase family
GZH91_RS04195	COG1017	nitric oxide dioxygenase activity
GZH91_RS04195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GZH91_RS04200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GZH91_RS04205	COG1592	Rubrerythrin
GZH91_RS04210	COG0247	lactate metabolic process
GZH91_RS04225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GZH91_RS04235	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GZH91_RS04240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GZH91_RS04245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GZH91_RS04250	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GZH91_RS04255	COG0142	geranyltranstransferase activity
GZH91_RS04335	COG1730	sister chromatid segregation
GZH91_RS04350	COG0753	catalase activity
GZH91_RS04355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GZH91_RS04360	COG0583	DNA-binding transcription factor activity
GZH91_RS04365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GZH91_RS04380	COG0788	formyltetrahydrofolate deformylase activity
GZH91_RS04385	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GZH91_RS04385	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GZH91_RS04390	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GZH91_RS04395	COG2824	Alkylphosphonate utilization operon protein PhnA
GZH91_RS04430	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GZH91_RS04450	COG0557	exoribonuclease II activity
GZH91_RS04460	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GZH91_RS04465	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GZH91_RS04475	COG0330	HflC and HflK could
GZH91_RS04480	COG0330	HflC and HflK could
GZH91_RS04485	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GZH91_RS04490	COG1923	regulation of RNA biosynthetic process
GZH91_RS04505	COG1160	GTP binding
GZH91_RS04520	COG0124	histidyl-tRNA synthetase
GZH91_RS04525	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GZH91_RS04540	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GZH91_RS04545	COG0105	UTP biosynthetic process
GZH91_RS04550	COG0037	tRNA processing
GZH91_RS04555	COG0825	malonyl-CoA metabolic process
GZH91_RS04560	COG1047	Peptidyl-prolyl cis-trans
GZH91_RS04570	COG2850	peptidyl-arginine hydroxylation
GZH91_RS04575	COG0436	Aminotransferase
GZH91_RS04595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GZH91_RS04615	COG1671	Belongs to the UPF0178 family
GZH91_RS04625	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GZH91_RS04680	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GZH91_RS04685	COG1597	lipid kinase activity
GZH91_RS04690	COG0671	phosphoesterase, PA-phosphatase related
GZH91_RS04710	COG0477	Major facilitator Superfamily
GZH91_RS04720	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GZH91_RS04725	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GZH91_RS04730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GZH91_RS04735	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GZH91_RS04740	COG1674	ftsk spoiiie
GZH91_RS04745	COG0492	ferredoxin-NADP+ reductase activity
GZH91_RS04750	COG2840	Smr protein MutS2
GZH91_RS04755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GZH91_RS04760	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GZH91_RS04790	COG0488	(ABC) transporter
GZH91_RS04805	COG5487	UPF0391 membrane protein
GZH91_RS04810	COG0667	Aldo Keto reductase
GZH91_RS04815	COG2226	methyltransferase
GZH91_RS04820	COG2814	Major facilitator Superfamily
GZH91_RS04830	COG3706	GGDEF domain
GZH91_RS04855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GZH91_RS04865	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GZH91_RS04865	COG1796	DNA polymerase
GZH91_RS04880	COG1454	alcohol dehydrogenase
GZH91_RS04945	COG0123	including yeast histone deacetylase and acetoin utilization protein
GZH91_RS04955	COG1238	metal cluster binding
GZH91_RS04985	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GZH91_RS04990	COG0058	SHG alpha-glucan phosphorylase activity
GZH91_RS05000	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GZH91_RS05015	COG0443	Heat shock 70 kDa protein
GZH91_RS05020	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GZH91_RS05030	COG0822	iron-sulfur transferase activity
GZH91_RS05035	COG1104	cysteine desulfurase activity
GZH91_RS05090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GZH91_RS05095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GZH91_RS05100	COG1538	Outer membrane efflux protein
GZH91_RS05105	COG1846	Transcriptional regulator
GZH91_RS05115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GZH91_RS05125	COG1566	PFAM secretion protein HlyD family protein
GZH91_RS05160	COG0745	RESPONSE REGULATOR receiver
GZH91_RS05165	COG4251	negative regulation of phosphorylation
GZH91_RS05195	COG0659	secondary active sulfate transmembrane transporter activity
GZH91_RS05205	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GZH91_RS05215	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GZH91_RS05255	COG3206	protein involved in exopolysaccharide biosynthesis
GZH91_RS05255	COG0489	protein tyrosine kinase activity
GZH91_RS05260	COG0489	protein tyrosine kinase activity
GZH91_RS05260	COG3206	protein involved in exopolysaccharide biosynthesis
GZH91_RS05270	COG0438	transferase activity, transferring glycosyl groups
GZH91_RS05280	COG0438	transferase activity, transferring glycosyl groups
GZH91_RS05290	COG1045	serine acetyltransferase
GZH91_RS05305	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GZH91_RS05315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GZH91_RS05320	COG0628	permease
GZH91_RS05340	COG3258	Cytochrome c
GZH91_RS05345	COG2863	cytochrome
GZH91_RS05365	COG3237	CsbD-like
GZH91_RS05385	COG2814	Major facilitator Superfamily
GZH91_RS05390	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GZH91_RS05400	COG0066	3-isopropylmalate dehydratase activity
GZH91_RS05405	COG0473	3-isopropylmalate dehydrogenase activity
GZH91_RS05415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GZH91_RS05430	COG0101	tRNA pseudouridine synthase activity
GZH91_RS05435	COG0135	phosphoribosylanthranilate isomerase activity
GZH91_RS05440	COG0133	tryptophan synthase activity
GZH91_RS05450	COG0159	tryptophan synthase activity
GZH91_RS05455	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GZH91_RS05460	COG0285	dihydrofolate synthase activity
GZH91_RS05470	COG1286	toxin biosynthetic process
GZH91_RS05490	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GZH91_RS05495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GZH91_RS05500	COG0215	cysteine-tRNA ligase activity
GZH91_RS05510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GZH91_RS05520	COG1127	ABC transporter
GZH91_RS05525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GZH91_RS05530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GZH91_RS05550	COG1131	(ABC) transporter
GZH91_RS05555	COG0842	Transport permease protein
GZH91_RS05560	COG0271	Belongs to the BolA IbaG family
GZH91_RS05565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GZH91_RS05570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GZH91_RS05580	COG0859	PFAM glycosyl transferase family 9
GZH91_RS05585	COG0438	transferase activity, transferring glycosyl groups
GZH91_RS05590	COG0367	asparagine synthase
GZH91_RS05625	COG4969	Belongs to the N-Me-Phe pilin family
GZH91_RS05670	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GZH91_RS05675	COG4115	mRNA cleavage
GZH91_RS05680	COG2161	toxin-antitoxin pair type II binding
GZH91_RS05685	COG1047	Peptidyl-prolyl cis-trans
GZH91_RS05690	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GZH91_RS05695	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GZH91_RS05700	COG0196	riboflavin kinase activity
GZH91_RS05750	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GZH91_RS05755	COG5002	protein histidine kinase activity
GZH91_RS05755	COG5001	Diguanylate cyclase
GZH91_RS05760	COG1570	exodeoxyribonuclease VII activity
GZH91_RS05765	COG0811	peptide transport
GZH91_RS05770	COG0848	biopolymer transport protein
GZH91_RS05780	COG1663	tetraacyldisaccharide 4'-kinase activity
GZH91_RS05785	COG1663	tetraacyldisaccharide 4'-kinase activity
GZH91_RS05785	COG2835	tetraacyldisaccharide 4'-kinase activity
GZH91_RS05790	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GZH91_RS05795	COG0563	adenylate kinase activity
GZH91_RS05805	COG0205	6-phosphofructokinase activity
GZH91_RS05815	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GZH91_RS05820	COG0753	catalase activity
GZH91_RS05835	COG3384	dioxygenase
GZH91_RS05845	COG0583	DNA-binding transcription factor activity
GZH91_RS05875	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GZH91_RS05880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GZH91_RS05885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GZH91_RS05890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GZH91_RS05895	COG1116	anion transmembrane transporter activity
GZH91_RS05925	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GZH91_RS05935	COG0583	DNA-binding transcription factor activity
GZH91_RS05945	COG0384	phenazine biosynthesis protein PhzF
GZH91_RS05955	COG4221	oxidoreductase activity
GZH91_RS05965	COG1902	pentaerythritol trinitrate reductase activity
GZH91_RS05990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GZH91_RS05995	COG0735	belongs to the Fur family
GZH91_RS06000	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GZH91_RS06005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GZH91_RS06010	COG0131	Imidazoleglycerol-phosphate dehydratase
GZH91_RS06015	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GZH91_RS06020	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GZH91_RS06025	COG0107	imidazoleglycerol-phosphate synthase activity
GZH91_RS06030	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GZH91_RS06035	COG0140	phosphoribosyl-ATP diphosphatase activity
GZH91_RS06045	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GZH91_RS06050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GZH91_RS06060	COG0004	ammonium transporteR
GZH91_RS06065	COG0583	DNA-binding transcription factor activity
GZH91_RS06095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GZH91_RS06095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GZH91_RS06105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GZH91_RS06135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GZH91_RS06140	COG1024	Enoyl-CoA hydratase
GZH91_RS06145	COG0784	Response regulator, receiver
GZH91_RS06145	COG2198	Histidine kinase
GZH91_RS06145	COG2205	protein histidine kinase activity
GZH91_RS06150	COG2204	response regulator
GZH91_RS06160	COG0281	malic enzyme
GZH91_RS06175	COG1053	succinate dehydrogenase
GZH91_RS06180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GZH91_RS06190	COG0372	Belongs to the citrate synthase family
GZH91_RS06195	COG0567	Dehydrogenase, E1 component
GZH91_RS06200	COG0508	dehydrogenase complex catalyzes the overall conversion of
GZH91_RS06210	COG0071	Belongs to the small heat shock protein (HSP20) family
GZH91_RS06250	COG1360	Flagellar Motor Protein
GZH91_RS06255	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GZH91_RS06275	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GZH91_RS06290	COG1191	sigma factor activity
GZH91_RS06295	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GZH91_RS06300	COG1360	Flagellar Motor Protein
GZH91_RS06325	COG1815	bacterial-type flagellum-dependent cell motility
GZH91_RS06330	COG1558	bacterial-type flagellum-dependent cell motility
GZH91_RS06345	COG4787	bacterial-type flagellum-dependent cell motility
GZH91_RS06355	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GZH91_RS06360	COG1706	bacterial-type flagellum-dependent cell motility
GZH91_RS06365	COG1705	Flagellar rod assembly protein muramidase FlgJ
GZH91_RS06365	COG3951	Flagellar rod assembly protein muramidase FlgJ
GZH91_RS06370	COG1256	bacterial-type flagellum assembly
GZH91_RS06375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GZH91_RS06385	COG0745	RESPONSE REGULATOR receiver
GZH91_RS06390	COG0643	Histidine kinase
GZH91_RS06390	COG2198	Histidine kinase
GZH91_RS06400	COG0840	transmembrane signaling receptor activity
GZH91_RS06405	COG0840	transmembrane signaling receptor activity
GZH91_RS06415	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GZH91_RS06420	COG2201	protein-glutamate methylesterase activity
GZH91_RS06425	COG0745	RESPONSE REGULATOR receiver
GZH91_RS06430	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GZH91_RS06440	COG3706	GGDEF domain
GZH91_RS06450	COG1987	bacterial-type flagellum assembly
GZH91_RS06465	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GZH91_RS06470	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GZH91_RS06490	COG1157	protein secretion by the type III secretion system
GZH91_RS06510	COG1677	Flagellar hook-basal body complex protein FliE
GZH91_RS06515	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
GZH91_RS06540	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GZH91_RS06540	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GZH91_RS06580	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GZH91_RS06595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GZH91_RS06600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GZH91_RS06620	COG0058	SHG alpha-glucan phosphorylase activity
GZH91_RS06630	COG2888	peptidyl-tyrosine sulfation
GZH91_RS06635	COG3228	Belongs to the MtfA family
GZH91_RS06650	COG2885	chlorophyll binding
GZH91_RS06680	COG4585	Histidine kinase
GZH91_RS06685	COG2197	response regulator
GZH91_RS06725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GZH91_RS06730	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GZH91_RS06740	COG0778	Nitroreductase
GZH91_RS06745	COG0425	Belongs to the sulfur carrier protein TusA family
GZH91_RS06760	COG1233	COG1233 Phytoene dehydrogenase and related
GZH91_RS06775	COG2048	Heterodisulfide reductase, subunit B
GZH91_RS06785	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GZH91_RS06800	COG0045	succinate-CoA ligase (ADP-forming) activity
GZH91_RS06805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GZH91_RS06825	COG0564	pseudouridine synthase activity
GZH91_RS06835	COG0729	surface antigen
GZH91_RS06855	COG0542	response to heat
GZH91_RS06880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GZH91_RS06885	COG1595	DNA-templated transcription, initiation
GZH91_RS06890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GZH91_RS06895	COG0586	Pfam SNARE associated Golgi protein
GZH91_RS06915	COG0791	NLP P60 protein
GZH91_RS06925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GZH91_RS06945	COG2084	Dehydrogenase
GZH91_RS06950	COG1064	alcohol dehydrogenase
GZH91_RS06960	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GZH91_RS06965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GZH91_RS06970	COG1420	regulation of RNA biosynthetic process
GZH91_RS06985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GZH91_RS07000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GZH91_RS07005	COG0497	DNA recombination
GZH91_RS07020	COG0735	belongs to the Fur family
GZH91_RS07025	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GZH91_RS07030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GZH91_RS07035	COG0505	Belongs to the CarA family
GZH91_RS07040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GZH91_RS07045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GZH91_RS07055	COG1534	Rna-binding protein
GZH91_RS07060	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GZH91_RS07065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GZH91_RS07070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GZH91_RS07075	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GZH91_RS07080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GZH91_RS07100	COG0149	triose-phosphate isomerase activity
GZH91_RS07105	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GZH91_RS07115	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GZH91_RS07120	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GZH91_RS07125	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GZH91_RS07130	COG0649	NAD binding
GZH91_RS07145	COG1034	ATP synthesis coupled electron transport
GZH91_RS07150	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GZH91_RS07155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GZH91_RS07165	COG0713	ATP synthesis coupled electron transport
GZH91_RS07180	COG1007	ATP synthesis coupled electron transport
GZH91_RS07190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GZH91_RS07200	COG1459	type II secretion system
GZH91_RS07210	COG4969	Belongs to the N-Me-Phe pilin family
GZH91_RS07215	COG4969	Belongs to the N-Me-Phe pilin family
GZH91_RS07220	COG4968	Prepilin-type N-terminal cleavage methylation domain
GZH91_RS07270	COG3409	Peptidoglycan-binding domain 1 protein
GZH91_RS07270	COG3267	Type II secretory pathway component ExeA
GZH91_RS07305	COG1573	uracil-dna glycosylase
GZH91_RS07365	COG2204	response regulator
GZH91_RS07370	COG3852	Histidine kinase
GZH91_RS07390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GZH91_RS07400	COG0802	atpase or kinase
GZH91_RS07405	COG0860	N-Acetylmuramoyl-L-alanine amidase
GZH91_RS07410	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GZH91_RS07420	COG0737	Belongs to the 5'-nucleotidase family
GZH91_RS07425	COG0513	Belongs to the DEAD box helicase family
GZH91_RS07455	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GZH91_RS07470	COG2096	Adenosyltransferase
GZH91_RS07495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GZH91_RS07515	COG0277	FAD linked oxidase domain protein
GZH91_RS07540	COG0166	Belongs to the GPI family
GZH91_RS07545	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GZH91_RS07550	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GZH91_RS07560	COG1449	Belongs to the glycosyl hydrolase 57 family
GZH91_RS07565	COG1047	Peptidyl-prolyl cis-trans
GZH91_RS07575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GZH91_RS07645	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GZH91_RS07650	COG5002	protein histidine kinase activity
GZH91_RS07655	COG0745	RESPONSE REGULATOR receiver
GZH91_RS07660	COG2132	Multicopper oxidase
GZH91_RS07680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GZH91_RS07685	COG0670	Belongs to the BI1 family
GZH91_RS07690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GZH91_RS07710	COG0363	glucosamine-6-phosphate deaminase activity
GZH91_RS07725	COG4660	Part of a membrane complex involved in electron transport
GZH91_RS07735	COG4658	electron transport chain
GZH91_RS07740	COG4656	Part of a membrane complex involved in electron transport
GZH91_RS07745	COG2878	Part of a membrane complex involved in electron transport
GZH91_RS07755	COG0686	Belongs to the AlaDH PNT family
GZH91_RS07760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GZH91_RS07765	COG0167	dihydroorotate dehydrogenase activity
GZH91_RS07770	COG0789	Transcriptional regulator
GZH91_RS07775	COG2608	mercury ion transmembrane transporter activity
GZH91_RS07790	COG1686	Belongs to the peptidase S11 family
GZH91_RS07800	COG0508	dehydrogenase complex catalyzes the overall conversion of
GZH91_RS07800	COG0022	dehydrogenase e1 component
GZH91_RS07805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GZH91_RS07810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GZH91_RS07815	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GZH91_RS07825	COG0268	Binds directly to 16S ribosomal RNA
GZH91_RS07840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GZH91_RS07845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GZH91_RS07850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GZH91_RS07855	COG0137	argininosuccinate synthase activity
GZH91_RS07860	COG3123	guanosine phosphorylase activity
GZH91_RS07865	COG1666	GTP binding
GZH91_RS07880	COG1162	GTPase activity
GZH91_RS07885	COG2154	pterin-4-alpha-carbinolamine dehydratase
GZH91_RS07895	COG0501	Belongs to the peptidase M48B family
GZH91_RS07900	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GZH91_RS07905	COG3577	Aspartyl protease
GZH91_RS07910	COG1187	pseudouridine synthase activity
GZH91_RS07920	COG2982	Protein involved in outer membrane biogenesis
GZH91_RS07935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GZH91_RS07940	COG2925	Exonuclease
GZH91_RS07950	COG3039	Transposase
GZH91_RS08015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GZH91_RS08030	COG3665	Urea carboxylase-associated protein
GZH91_RS08035	COG0439	Biotin carboxylase
GZH91_RS08070	COG1028	Short-chain dehydrogenase reductase Sdr
GZH91_RS08115	COG1136	(ABC) transporter
GZH91_RS08130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GZH91_RS08155	COG1741	Belongs to the pirin family
GZH91_RS08160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GZH91_RS08185	COG0356	it plays a direct role in the translocation of protons across the membrane
GZH91_RS08190	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GZH91_RS08195	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GZH91_RS08200	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GZH91_RS08205	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GZH91_RS08215	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GZH91_RS08220	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GZH91_RS08225	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GZH91_RS08260	COG1858	cytochrome C peroxidase
GZH91_RS08275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GZH91_RS08280	COG1116	anion transmembrane transporter activity
GZH91_RS08285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GZH91_RS08290	COG1116	anion transmembrane transporter activity
GZH91_RS08305	COG0509	glycine decarboxylation via glycine cleavage system
GZH91_RS08315	COG1999	signal sequence binding
GZH91_RS08340	COG4191	Histidine kinase
GZH91_RS08345	COG4566	intracellular signal transduction
GZH91_RS08355	COG4232	protein-disulfide reductase activity
GZH91_RS08360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GZH91_RS08375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GZH91_RS08390	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GZH91_RS08395	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GZH91_RS08400	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GZH91_RS08405	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GZH91_RS08410	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GZH91_RS08415	COG0072	phenylalanine-tRNA ligase activity
GZH91_RS08415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GZH91_RS08420	COG0776	regulation of translation
GZH91_RS08435	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GZH91_RS08440	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GZH91_RS08445	COG4942	peptidase
GZH91_RS08445	COG1388	LysM domain
GZH91_RS08455	COG1011	Hydrolase
GZH91_RS08465	COG0436	Aminotransferase
GZH91_RS08485	COG1199	ATP-dependent helicase activity
GZH91_RS08495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GZH91_RS08520	COG3158	transport of potassium into the cell
GZH91_RS08535	COG0709	Synthesizes selenophosphate from selenide and ATP
GZH91_RS08540	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GZH91_RS08550	COG0678	peroxiredoxin activity
GZH91_RS08550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GZH91_RS08555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GZH91_RS08580	COG2204	response regulator
GZH91_RS08650	COG0298	carbon dioxide binding
GZH91_RS08675	COG0375	protein maturation
GZH91_RS08685	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GZH91_RS08720	COG2308	Evidence 4 Homologs of previously reported genes of
GZH91_RS08750	COG1923	regulation of RNA biosynthetic process
GZH91_RS08755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GZH91_RS08760	COG0271	Belongs to the BolA IbaG family
GZH91_RS08765	COG2350	Protein conserved in bacteria
GZH91_RS08770	COG2917	probably involved in intracellular septation
GZH91_RS08780	COG0613	PHP domain protein
GZH91_RS08785	COG0009	L-threonylcarbamoyladenylate synthase
GZH91_RS08790	COG1994	Peptidase M50
GZH91_RS08795	COG0180	Tryptophanyl-tRNA synthetase
GZH91_RS08800	COG5002	protein histidine kinase activity
GZH91_RS08805	COG2204	response regulator
GZH91_RS08815	COG0437	4 iron, 4 sulfur cluster binding
GZH91_RS08820	COG2864	formate dehydrogenase
GZH91_RS08835	COG3276	selenocysteine insertion sequence binding
GZH91_RS08845	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GZH91_RS08850	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GZH91_RS08880	COG0625	glutathione transferase activity
GZH91_RS08900	COG1595	DNA-templated transcription, initiation
GZH91_RS08910	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GZH91_RS08915	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GZH91_RS08920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GZH91_RS08925	COG0723	plastoquinol--plastocyanin reductase activity
GZH91_RS08930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GZH91_RS08935	COG2857	Cytochrome c1
GZH91_RS08940	COG0625	glutathione transferase activity
GZH91_RS08945	COG2969	positive regulation of protein catabolic process
GZH91_RS08960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GZH91_RS08975	COG5265	(ABC) transporter
GZH91_RS08980	COG0676	glucose-6-phosphate 1-epimerase activity
GZH91_RS09005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GZH91_RS09035	COG0450	alkyl hydroperoxide reductase
GZH91_RS09050	COG2217	Heavy metal translocating P-type atpase
GZH91_RS09090	COG0475	glutathione-regulated potassium exporter activity
GZH91_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
GZH91_RS09115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GZH91_RS09175	COG1070	Carbohydrate kinase
GZH91_RS09185	COG1331	Highly conserved protein containing a thioredoxin domain
GZH91_RS09200	COG1999	signal sequence binding
GZH91_RS09250	COG2274	protein secretion by the type I secretion system
GZH91_RS09255	COG2326	polyphosphate kinase activity
GZH91_RS09260	COG0714	Associated with various cellular activities
GZH91_RS09275	COG2304	oxidoreductase activity
GZH91_RS09280	COG2304	oxidoreductase activity
GZH91_RS09315	COG1305	Transglutaminase-like
GZH91_RS09335	COG2171	N-acyltransferase activity
GZH91_RS09370	COG3263	regulation of cellular component size
GZH91_RS09375	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
GZH91_RS09380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GZH91_RS09385	COG0589	response to stress
GZH91_RS09390	COG3588	fructose-bisphosphate aldolase
GZH91_RS09405	COG2814	Major facilitator Superfamily
GZH91_RS09410	COG1566	PFAM secretion protein HlyD family protein
GZH91_RS09415	COG1538	Outer membrane efflux protein
GZH91_RS09435	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GZH91_RS09455	COG0175	sulfate reduction
GZH91_RS09460	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GZH91_RS09465	COG0730	response to heat
GZH91_RS09470	COG0583	DNA-binding transcription factor activity
GZH91_RS09495	COG2204	response regulator
GZH91_RS09505	COG1024	Enoyl-CoA hydratase
GZH91_RS09505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GZH91_RS09510	COG0309	Hydrogenase expression formation protein (HypE)
GZH91_RS09515	COG0409	Hydrogenase expression formation protein
GZH91_RS09520	COG0298	carbon dioxide binding
GZH91_RS09525	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GZH91_RS09530	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GZH91_RS09540	COG0375	protein maturation
GZH91_RS09550	COG1773	rubredoxin
GZH91_RS09560	COG1773	rubredoxin
GZH91_RS09565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GZH91_RS09595	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GZH91_RS09600	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GZH91_RS09660	COG0640	Transcriptional regulator
GZH91_RS09680	COG1742	UPF0060 membrane protein
GZH91_RS09725	COG1285	pathogenesis
GZH91_RS09740	COG0583	DNA-binding transcription factor activity
GZH91_RS09750	COG1902	pentaerythritol trinitrate reductase activity
GZH91_RS09755	COG1309	transcriptional regulator
GZH91_RS09765	COG2818	Glycosylase
GZH91_RS09785	COG4962	Type ii secretion system protein e
GZH91_RS09800	COG3451	type IV secretory pathway VirB4
GZH91_RS09830	COG2948	multi-organism process
GZH91_RS09845	COG0582	viral genome integration into host DNA
GZH91_RS09850	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GZH91_RS09850	COG0519	Catalyzes the synthesis of GMP from XMP
GZH91_RS09865	COG2914	Belongs to the UPF0125 (RnfH) family
GZH91_RS09870	COG2867	negative regulation of translational initiation
GZH91_RS09875	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GZH91_RS09880	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GZH91_RS09885	COG4181	ATPase activity
GZH91_RS09900	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GZH91_RS09915	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GZH91_RS09920	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GZH91_RS09925	COG1355	regulation of microtubule-based process
GZH91_RS09950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GZH91_RS09955	COG0560	Phosphoserine phosphatase
GZH91_RS09960	COG5002	protein histidine kinase activity
GZH91_RS09960	COG5001	Diguanylate cyclase
GZH91_RS09975	COG0328	RNA-DNA hybrid ribonuclease activity
GZH91_RS09980	COG2226	methyltransferase
GZH91_RS09985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GZH91_RS09990	COG1388	LysM domain
GZH91_RS09990	COG0741	lytic transglycosylase activity
GZH91_RS09995	COG4172	Belongs to the ABC transporter superfamily
GZH91_RS10000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GZH91_RS10005	COG0601	transmembrane transport
GZH91_RS10025	COG3154	lipid carrier protein
GZH91_RS10035	COG0826	peptidase U32
GZH91_RS10050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GZH91_RS10070	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GZH91_RS10075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GZH91_RS10080	COG0740	serine-type endopeptidase activity
GZH91_RS10085	COG0544	peptidyl-prolyl cis-trans isomerase activity
GZH91_RS10095	COG1562	ergosterol biosynthetic process
GZH91_RS10105	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GZH91_RS10110	COG1028	Short-chain dehydrogenase reductase Sdr
GZH91_RS10115	COG0515	serine threonine protein kinase
GZH91_RS10130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GZH91_RS10135	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GZH91_RS10145	COG0284	orotidine-5'-phosphate decarboxylase activity
GZH91_RS10150	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GZH91_RS10160	COG0776	regulation of translation
GZH91_RS10170	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GZH91_RS10175	COG0287	Prephenate dehydrogenase
GZH91_RS10180	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GZH91_RS10185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GZH91_RS10195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GZH91_RS10200	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GZH91_RS10210	COG0402	S-adenosylhomocysteine deaminase activity
GZH91_RS10215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GZH91_RS10220	COG0546	phosphoglycolate phosphatase activity
GZH91_RS10230	COG0789	Transcriptional regulator
GZH91_RS10360	COG1475	DNA binding
GZH91_RS10415	COG0616	signal peptide processing
GZH91_RS10525	COG1401	restriction endodeoxyribonuclease activity
GZH91_RS10540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GZH91_RS10650	COG0582	viral genome integration into host DNA
GZH91_RS10655	COG4584	PFAM Integrase catalytic
GZH91_RS10660	COG1484	DNA-dependent DNA replication
GZH91_RS10725	COG0326	Molecular chaperone. Has ATPase activity
GZH91_RS10735	COG1132	(ABC) transporter
GZH91_RS10740	COG0189	ligase activity
GZH91_RS10740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GZH91_RS10745	COG1181	Belongs to the D-alanine--D-alanine ligase family
GZH91_RS10745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GZH91_RS10750	COG0789	Transcriptional regulator
GZH91_RS10755	COG2217	Heavy metal translocating P-type atpase
GZH91_RS10805	COG0617	tRNA 3'-terminal CCA addition
GZH91_RS10845	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GZH91_RS10890	COG1331	Highly conserved protein containing a thioredoxin domain
GZH91_RS10905	COG0556	nucleotide-excision repair
GZH91_RS10910	COG0436	Aminotransferase
GZH91_RS10915	COG2067	long-chain fatty acid transport protein
GZH91_RS10930	COG0776	regulation of translation
GZH91_RS10935	COG3706	GGDEF domain
GZH91_RS10970	COG3039	Transposase
GZH91_RS10990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GZH91_RS11010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GZH91_RS11025	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GZH91_RS11045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GZH91_RS11065	COG3383	formate dehydrogenase (NAD+) activity
GZH91_RS11070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GZH91_RS11080	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GZH91_RS11085	COG2826	transposase and inactivated derivatives, IS30 family
GZH91_RS11090	COG3039	Transposase
GZH91_RS11105	COG0672	)-iron permease
GZH91_RS11130	COG0650	Formate hydrogenlyase subunit 4
GZH91_RS11140	COG0651	ATP synthesis coupled electron transport
GZH91_RS11150	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GZH91_RS11155	COG0651	ATP synthesis coupled electron transport
GZH91_RS11190	COG3459	Glycosyltransferase 36 associated
GZH91_RS11215	COG1902	pentaerythritol trinitrate reductase activity
GZH91_RS11220	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GZH91_RS11240	COG1028	Short-chain dehydrogenase reductase Sdr
GZH91_RS11240	COG0604	alcohol dehydrogenase
GZH91_RS11240	COG3321	synthase
GZH91_RS11245	COG0156	8-amino-7-oxononanoate synthase activity
GZH91_RS11255	COG1368	sulfuric ester hydrolase activity
GZH91_RS11260	COG0300	oxidoreductase activity
GZH91_RS11275	COG0438	transferase activity, transferring glycosyl groups
GZH91_RS11380	COG3660	Nucleoside-diphosphate-sugar epimerase
GZH91_RS11390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GZH91_RS11395	COG0443	Heat shock 70 kDa protein
GZH91_RS11400	COG0484	heat shock protein binding
GZH91_RS11410	COG0084	hydrolase, TatD family'
GZH91_RS11425	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GZH91_RS11430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GZH91_RS11440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GZH91_RS11450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GZH91_RS11455	COG1028	Short-chain dehydrogenase reductase Sdr
GZH91_RS11460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GZH91_RS11470	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GZH91_RS11475	COG1399	metal-binding, possibly nucleic acid-binding protein
GZH91_RS11480	COG0439	Biotin carboxylase
GZH91_RS11485	COG0511	ligase activity, forming carbon-carbon bonds
GZH91_RS11485	COG5016	pyruvate
GZH91_RS11490	COG0424	maF-like protein
GZH91_RS11505	COG1595	DNA-templated transcription, initiation
GZH91_RS11515	COG0616	signal peptide processing
GZH91_RS11515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GZH91_RS11525	COG0546	phosphoglycolate phosphatase activity
GZH91_RS11530	COG0564	pseudouridine synthase activity
GZH91_RS11535	COG1530	ribonuclease E activity
GZH91_RS11545	COG2201	protein-glutamate methylesterase activity
GZH91_RS11560	COG0835	chemotaxis
GZH91_RS11570	COG0835	chemotaxis
GZH91_RS11575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GZH91_RS11595	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GZH91_RS11600	COG2081	HI0933 family
GZH91_RS11615	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GZH91_RS11620	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GZH91_RS11625	COG3549	Plasmid maintenance system killer
GZH91_RS11645	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GZH91_RS11655	COG0330	HflC and HflK could
GZH91_RS11670	COG1993	acr, cog1993
GZH91_RS11675	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GZH91_RS11685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GZH91_RS11695	COG0640	Transcriptional regulator
GZH91_RS11710	COG0446	pyridine nucleotide-disulphide oxidoreductase
GZH91_RS11730	COG2204	response regulator
GZH91_RS11760	COG0477	Major facilitator Superfamily
GZH91_RS11780	COG2217	Heavy metal translocating P-type atpase
GZH91_RS11795	COG0477	Major facilitator Superfamily
GZH91_RS11820	COG0671	phosphoesterase, PA-phosphatase related
GZH91_RS11835	COG0537	adenosine 5'-monophosphoramidase activity
GZH91_RS11840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GZH91_RS11845	COG0314	molybdopterin synthase activity
GZH91_RS11850	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GZH91_RS11855	COG0303	'Molybdopterin
GZH91_RS11860	COG1763	Mo-molybdopterin cofactor biosynthetic process
GZH91_RS11865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GZH91_RS11880	COG0482	sulfurtransferase activity
GZH91_RS11885	COG0297	glycogen (starch) synthase activity
GZH91_RS11890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GZH91_RS11930	COG0542	response to heat
GZH91_RS11935	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GZH91_RS11940	COG1278	Cold shock
GZH91_RS11970	COG0837	glucose binding
GZH91_RS11980	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GZH91_RS11990	COG3012	SEC-C Motif Domain Protein
GZH91_RS11990	COG3318	Belongs to the UPF0149 family
GZH91_RS12000	COG3954	Phosphoribulokinase
GZH91_RS12015	COG0583	DNA-binding transcription factor activity
GZH91_RS12035	COG0631	protein serine/threonine phosphatase activity
GZH91_RS12040	COG2815	serine threonine protein kinase
GZH91_RS12040	COG0515	serine threonine protein kinase
GZH91_RS12055	COG0123	including yeast histone deacetylase and acetoin utilization protein
GZH91_RS12085	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GZH91_RS12090	COG1704	LemA family
GZH91_RS12095	COG1573	uracil-dna glycosylase
GZH91_RS12100	COG0456	acetyltransferase
GZH91_RS12105	COG1214	PFAM Peptidase M22, glycoprotease
GZH91_RS12120	COG2200	EAL domain
GZH91_RS12140	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GZH91_RS12145	COG4221	oxidoreductase activity
GZH91_RS12170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GZH91_RS12195	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GZH91_RS12200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GZH91_RS12210	COG2095	MarC family integral membrane protein
GZH91_RS12215	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GZH91_RS12225	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GZH91_RS12230	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GZH91_RS12235	COG3047	cAMP biosynthetic process
GZH91_RS12240	COG2217	Heavy metal translocating P-type atpase
GZH91_RS12250	COG3278	Belongs to the heme-copper respiratory oxidase family
GZH91_RS12270	COG0348	domain, Protein
GZH91_RS12295	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GZH91_RS12295	COG0047	phosphoribosylformylglycinamidine synthase activity
GZH91_RS12305	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GZH91_RS12315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GZH91_RS12320	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GZH91_RS12325	COG3115	cell septum assembly
GZH91_RS12330	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GZH91_RS12335	COG0148	phosphopyruvate hydratase activity
GZH91_RS12340	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GZH91_RS12345	COG0504	CTP synthase activity
GZH91_RS12365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GZH91_RS12385	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GZH91_RS12390	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GZH91_RS12395	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GZH91_RS12400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GZH91_RS12405	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GZH91_RS12425	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GZH91_RS12435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GZH91_RS12440	COG0233	cytoplasmic translational termination
GZH91_RS12445	COG0528	UMP kinase activity
GZH91_RS12450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GZH91_RS12455	COG0052	Belongs to the universal ribosomal protein uS2 family
GZH91_RS12460	COG1132	(ABC) transporter
GZH91_RS12470	COG1522	sequence-specific DNA binding
GZH91_RS12475	COG0730	response to heat
GZH91_RS12500	COG2204	response regulator
GZH91_RS12510	COG2205	protein histidine kinase activity
GZH91_RS12530	COG0322	excinuclease ABC activity
GZH91_RS12540	COG1573	uracil-dna glycosylase
GZH91_RS12550	COG1472	Belongs to the glycosyl hydrolase 3 family
GZH91_RS12555	COG0736	holo-[acyl-carrier-protein] synthase activity
GZH91_RS12580	COG3039	Transposase
GZH91_RS12585	COG5001	Diguanylate cyclase
GZH91_RS12585	COG5002	protein histidine kinase activity
GZH91_RS12615	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GZH91_RS12620	COG0513	Belongs to the DEAD box helicase family
GZH91_RS12630	COG0242	peptide deformylase activity
GZH91_RS12635	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GZH91_RS12640	COG0024	Methionine aminopeptidase
GZH91_RS12655	COG5433	transposase activity
GZH91_RS12665	COG2948	multi-organism process
GZH91_RS12680	COG3846	protein secretion by the type IV secretion system
GZH91_RS12690	COG3451	type IV secretory pathway VirB4
GZH91_RS12700	COG3838	Conjugal transfer protein Trbc
GZH91_RS12705	COG4962	Type ii secretion system protein e
GZH91_RS12725	COG0583	DNA-binding transcription factor activity
GZH91_RS12730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GZH91_RS12745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GZH91_RS12775	COG2207	Transcriptional regulator
GZH91_RS12785	COG4959	Type IV secretory pathway protease TraF
GZH91_RS12800	COG1192	Involved in chromosome partitioning
GZH91_RS12835	COG5489	Protein of unknown function (DUF736)
GZH91_RS12860	COG1475	DNA binding
GZH91_RS12875	COG2003	Belongs to the UPF0758 family
GZH91_RS12880	COG3077	Addiction module antitoxin, RelB DinJ family
GZH91_RS12920	COG0779	Required for maturation of 30S ribosomal subunits
GZH91_RS12925	COG0195	Participates in both transcription termination and antitermination
GZH91_RS12925	COG2251	uridine kinase activity
GZH91_RS12930	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GZH91_RS12935	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GZH91_RS12940	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GZH91_RS12945	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GZH91_RS12950	COG1185	polyribonucleotide nucleotidyltransferase activity
GZH91_RS12960	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GZH91_RS12965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GZH91_RS12970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GZH91_RS12990	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GZH91_RS13005	COG3284	Transcriptional regulator
GZH91_RS13035	COG0076	glutamate decarboxylase activity
GZH91_RS13060	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GZH91_RS13070	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
GZH91_RS13095	COG0702	epimerase
GZH91_RS13110	COG1229	Formylmethanofuran dehydrogenase subunit A
GZH91_RS13115	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
GZH91_RS13130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GZH91_RS13150	COG1116	anion transmembrane transporter activity
GZH91_RS13155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GZH91_RS13205	COG3039	Transposase
GZH91_RS13215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GZH91_RS13230	COG3383	formate dehydrogenase (NAD+) activity
GZH91_RS13235	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GZH91_RS13245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GZH91_RS13265	COG4191	Histidine kinase
GZH91_RS13270	COG1100	Small GTP-binding protein
GZH91_RS13275	COG2204	response regulator
GZH91_RS13285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GZH91_RS13285	COG4191	Histidine kinase
GZH91_RS13290	COG1639	'signal transduction protein
GZH91_RS13330	COG1492	cobalamin metabolic process
GZH91_RS13350	COG0778	Nitroreductase
GZH91_RS13380	COG2875	Belongs to the precorrin methyltransferase family
GZH91_RS13390	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GZH91_RS13395	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GZH91_RS13420	COG3411	Ferredoxin
GZH91_RS13440	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GZH91_RS13445	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GZH91_RS13475	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GZH91_RS13490	COG3459	Glycosyltransferase 36 associated
GZH91_RS13520	COG3118	belongs to the thioredoxin family
GZH91_RS13545	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GZH91_RS13550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GZH91_RS13555	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GZH91_RS13570	COG0531	amino acid
GZH91_RS13635	COG1518	maintenance of DNA repeat elements
GZH91_RS13640	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GZH91_RS13660	COG0312	modulator of DNA gyrase
GZH91_RS13675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GZH91_RS13680	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GZH91_RS13695	COG0720	synthase
GZH91_RS13700	COG1881	PFAM PEBP family protein
GZH91_RS13720	COG1643	Atp-dependent helicase
GZH91_RS13725	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GZH91_RS13740	COG0521	Mo-molybdopterin cofactor biosynthetic process
GZH91_RS13750	COG0429	hydrolase of the alpha beta-hydrolase fold
GZH91_RS13760	COG0617	tRNA 3'-terminal CCA addition
GZH91_RS13765	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GZH91_RS13770	COG1428	Deoxynucleoside kinase
GZH91_RS13775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GZH91_RS13780	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GZH91_RS13785	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GZH91_RS13830	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GZH91_RS13835	COG0343	queuine tRNA-ribosyltransferase activity
GZH91_RS13840	COG1862	Preprotein translocase
GZH91_RS13845	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GZH91_RS13850	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GZH91_RS13855	COG0586	Pfam SNARE associated Golgi protein
GZH91_RS13870	COG2866	Carboxypeptidase
GZH91_RS13880	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GZH91_RS13885	COG1381	Involved in DNA repair and RecF pathway recombination
GZH91_RS13890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GZH91_RS13895	COG0571	ribonuclease III activity
GZH91_RS13905	COG0681	Belongs to the peptidase S26 family
GZH91_RS13910	COG0481	GTPase activity
GZH91_RS13920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GZH91_RS13930	COG3026	antisigma factor binding
GZH91_RS13945	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GZH91_RS13955	COG0354	folic acid binding
GZH91_RS13980	COG1902	pentaerythritol trinitrate reductase activity
GZH91_RS13995	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GZH91_RS13995	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GZH91_RS14000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GZH91_RS14005	COG0305	Participates in initiation and elongation during chromosome replication
GZH91_RS14010	COG0359	binds to the 23S rRNA
GZH91_RS14015	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GZH91_RS14020	COG2965	DNA replication, synthesis of RNA primer
GZH91_RS14025	COG0360	Binds together with S18 to 16S ribosomal RNA
GZH91_RS14040	COG1722	exodeoxyribonuclease VII activity
GZH91_RS14045	COG0142	geranyltranstransferase activity
GZH91_RS14050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GZH91_RS14055	COG1469	GTP cyclohydrolase I activity
GZH91_RS14075	COG0505	Belongs to the CarA family
GZH91_RS14090	COG2046	Belongs to the sulfate adenylyltransferase family
GZH91_RS14125	COG3300	MHYT domain
GZH91_RS14125	COG5001	Diguanylate cyclase
GZH91_RS14130	COG3039	Transposase
GZH91_RS14135	COG3706	GGDEF domain
GZH91_RS14155	COG3220	belongs to the UPF0276 family
GZH91_RS14190	COG1595	DNA-templated transcription, initiation
GZH91_RS14235	COG0785	Cytochrome C biogenesis protein
GZH91_RS14255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GZH91_RS14280	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GZH91_RS14285	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GZH91_RS14310	COG1595	DNA-templated transcription, initiation
GZH91_RS14315	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GZH91_RS14335	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GZH91_RS14370	COG0848	biopolymer transport protein
GZH91_RS14375	COG0811	peptide transport
GZH91_RS14390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GZH91_RS14395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GZH91_RS14400	COG0450	alkyl hydroperoxide reductase
GZH91_RS14410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GZH91_RS14415	COG2076	Multidrug Resistance protein
GZH91_RS14420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GZH91_RS14430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GZH91_RS14430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GZH91_RS14460	COG0726	polysaccharide deacetylase
GZH91_RS14470	COG2183	response to ionizing radiation
GZH91_RS14475	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GZH91_RS14480	COG0598	Magnesium transport protein CorA
GZH91_RS14485	COG0514	ATP-dependent DNA helicase (RecQ)
GZH91_RS14530	COG4095	Psort location CytoplasmicMembrane, score
GZH91_RS14545	COG1982	Orn Lys Arg decarboxylase major
GZH91_RS14550	COG0717	Belongs to the dCTP deaminase family
GZH91_RS14555	COG0489	protein tyrosine kinase activity
GZH91_RS14575	COG0494	nUDIX hydrolase
GZH91_RS14585	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GZH91_RS14595	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GZH91_RS14600	COG0442	prolyl-tRNA aminoacylation
GZH91_RS14605	COG0741	lytic transglycosylase activity
GZH91_RS14625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GZH91_RS14630	COG1027	Aspartate ammonia-lyase
GZH91_RS14675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GZH91_RS14680	COG1183	phosphatidylcholine synthase activity
GZH91_RS14685	COG0688	phosphatidylethanolamine metabolic process
GZH91_RS14690	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GZH91_RS14700	COG0028	Belongs to the TPP enzyme family
GZH91_RS14705	COG1193	negative regulation of DNA recombination
GZH91_RS14725	COG1714	RDD family
GZH91_RS14735	COG0795	lipopolysaccharide-transporting ATPase activity
GZH91_RS14740	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GZH91_RS14755	COG0525	valine-tRNA ligase activity
GZH91_RS14800	COG0095	Lipoate-protein ligase
GZH91_RS14810	COG0509	glycine decarboxylation via glycine cleavage system
GZH91_RS14820	COG0509	glycine decarboxylation via glycine cleavage system
GZH91_RS14825	COG2048	Heterodisulfide reductase, subunit B
GZH91_RS14855	COG2210	Belongs to the sulfur carrier protein TusA family
GZH91_RS14860	COG0425	Belongs to the sulfur carrier protein TusA family
GZH91_RS14875	COG0437	4 iron, 4 sulfur cluster binding
GZH91_RS14880	COG0243	molybdopterin cofactor binding
GZH91_RS14915	COG0714	Associated with various cellular activities
GZH91_RS14935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GZH91_RS14950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GZH91_RS14950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GZH91_RS14955	COG0640	Transcriptional regulator
GZH91_RS14965	COG5002	protein histidine kinase activity
GZH91_RS14965	COG5001	Diguanylate cyclase
GZH91_RS14970	COG0315	cyclic pyranopterin monophosphate synthase activity
GZH91_RS14975	COG4783	chaperone-mediated protein folding
GZH91_RS14995	COG3258	Cytochrome c
GZH91_RS15005	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GZH91_RS15035	COG3267	Type II secretory pathway component ExeA
GZH91_RS15035	COG3409	Peptidoglycan-binding domain 1 protein
GZH91_RS15040	COG1450	Type ii and iii secretion system protein
GZH91_RS15050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GZH91_RS15055	COG1459	type II secretion system
GZH91_RS15115	COG3039	Transposase
GZH91_RS15135	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GZH91_RS15155	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GZH91_RS15170	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GZH91_RS15175	COG1660	Displays ATPase and GTPase activities
GZH91_RS15200	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GZH91_RS15210	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GZH91_RS15225	COG0210	DNA helicase
GZH91_RS15230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GZH91_RS15240	COG1612	heme a metabolic process
GZH91_RS15245	COG1064	alcohol dehydrogenase
GZH91_RS15255	COG0495	leucyl-tRNA aminoacylation
GZH91_RS15260	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GZH91_RS15275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GZH91_RS15280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GZH91_RS15285	COG0799	negative regulation of ribosome biogenesis
GZH91_RS15295	COG0424	maF-like protein
GZH91_RS15300	COG1530	ribonuclease E activity
GZH91_RS15305	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GZH91_RS15310	COG1872	DUF167
GZH91_RS15315	COG0762	integral membrane protein
GZH91_RS15360	COG2318	DinB family
GZH91_RS15365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GZH91_RS15380	COG0277	FAD linked oxidase domain protein
GZH91_RS15400	COG0745	RESPONSE REGULATOR receiver
GZH91_RS15405	COG2226	methyltransferase
GZH91_RS15415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GZH91_RS15420	COG4145	pantothenate transmembrane transporter activity
GZH91_RS15430	COG2046	Belongs to the sulfate adenylyltransferase family
GZH91_RS15430	COG0529	Catalyzes the synthesis of activated sulfate
GZH91_RS15455	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GZH91_RS15495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GZH91_RS15500	COG0784	Response regulator, receiver
GZH91_RS15500	COG2205	protein histidine kinase activity
GZH91_RS15500	COG2198	Histidine kinase
GZH91_RS15505	COG2204	response regulator
GZH91_RS15545	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GZH91_RS15555	COG1333	cytochrome c biogenesis protein
GZH91_RS15560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GZH91_RS15565	COG3039	Transposase
GZH91_RS15585	COG3039	Transposase
GZH91_RS15605	COG3039	Transposase
GZH91_RS15610	COG1201	RNA secondary structure unwinding
GZH91_RS15620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GZH91_RS15640	COG1136	(ABC) transporter
GZH91_RS15640	COG0577	efflux transmembrane transporter activity
GZH91_RS15645	COG4591	ABC-type transport system involved in lipoprotein release permease component
GZH91_RS15655	COG1136	(ABC) transporter
GZH91_RS15655	COG0577	efflux transmembrane transporter activity
GZH91_RS15665	COG4783	chaperone-mediated protein folding
GZH91_RS15675	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GZH91_RS15680	COG0138	bifunctional purine biosynthesis protein purh
GZH91_RS15685	COG0151	Belongs to the GarS family
GZH91_RS15690	COG0009	L-threonylcarbamoyladenylate synthase
GZH91_RS15695	COG0408	coproporphyrinogen oxidase activity
GZH91_RS15705	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GZH91_RS15710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GZH91_RS15715	COG2890	protein-(glutamine-N5) methyltransferase activity
GZH91_RS15730	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GZH91_RS15750	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GZH91_RS15755	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GZH91_RS15760	COG0352	thiamine-phosphate diphosphorylase activity
GZH91_RS15770	COG1773	rubredoxin
GZH91_RS15790	COG0840	transmembrane signaling receptor activity
GZH91_RS15800	COG1968	undecaprenyl-diphosphatase activity
GZH91_RS15805	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GZH91_RS15810	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GZH91_RS15820	COG1538	Outer membrane efflux protein
GZH91_RS15835	COG4636	protein conserved in cyanobacteria
GZH91_RS15860	COG1216	Glycosyl transferase, family 2
GZH91_RS15905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GZH91_RS15960	COG0438	transferase activity, transferring glycosyl groups
GZH91_RS15960	COG1216	Glycosyl transferase, family 2
GZH91_RS16035	COG0653	protein targeting
GZH91_RS16065	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GZH91_RS16080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GZH91_RS16085	COG1181	Belongs to the D-alanine--D-alanine ligase family
GZH91_RS16090	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GZH91_RS16095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GZH91_RS16100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GZH91_RS16105	COG0772	Belongs to the SEDS family
GZH91_RS16110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GZH91_RS16115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GZH91_RS16120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GZH91_RS16125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GZH91_RS16140	COG0275	rRNA processing
GZH91_RS16145	COG2001	Belongs to the MraZ family
GZH91_RS16170	COG3852	Histidine kinase
GZH91_RS16195	COG0723	plastoquinol--plastocyanin reductase activity
GZH91_RS16210	COG1028	Short-chain dehydrogenase reductase Sdr
GZH91_RS16215	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GZH91_RS16240	COG1294	oxidase, subunit
GZH91_RS16245	COG1271	oxidase subunit
GZH91_RS16260	COG0418	dihydroorotase activity
GZH91_RS16265	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GZH91_RS16270	COG0792	nuclease activity
GZH91_RS16275	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GZH91_RS16280	COG2823	Periplasmic or secreted lipoprotein
GZH91_RS16285	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GZH91_RS16290	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GZH91_RS16305	COG0697	spore germination
GZH91_RS16340	COG0625	glutathione transferase activity
GZH91_RS16385	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GZH91_RS16390	COG0459	protein refolding
GZH91_RS16400	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GZH91_RS16430	COG1414	Transcriptional regulator
GZH91_RS16445	COG1556	Lactate utilization protein
GZH91_RS16490	COG2084	Dehydrogenase
GZH91_RS16495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GZH91_RS16510	COG0277	FAD linked oxidase domain protein
GZH91_RS16515	COG0277	FAD linked oxidase domain protein
GZH91_RS16520	COG0247	lactate metabolic process
GZH91_RS16525	COG0067	glutamate synthase
GZH91_RS16525	COG0069	glutamate synthase activity
GZH91_RS16525	COG0070	glutamate synthase
GZH91_RS16530	COG0493	'glutamate synthase
GZH91_RS16535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GZH91_RS16540	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GZH91_RS16545	COG0018	arginyl-trna synthetase
GZH91_RS16565	COG2197	response regulator
GZH91_RS16575	COG0494	nUDIX hydrolase
GZH91_RS16590	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GZH91_RS16600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GZH91_RS16645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GZH91_RS16675	COG4654	Cytochrome c, class I
GZH91_RS16685	COG0129	dihydroxy-acid dehydratase activity
GZH91_RS16690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GZH91_RS16700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GZH91_RS16705	COG1702	phosphate starvation-inducible protein PhoH
GZH91_RS16710	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GZH91_RS16715	COG4535	Mg2 and Co2 transporter CorC
GZH91_RS16735	COG0469	pyruvate kinase activity
GZH91_RS16740	COG0126	phosphoglycerate kinase activity
GZH91_RS16745	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GZH91_RS16750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GZH91_RS16765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GZH91_RS16770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GZH91_RS16770	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GZH91_RS16780	COG5002	protein histidine kinase activity
GZH91_RS16780	COG5001	Diguanylate cyclase
GZH91_RS16785	COG0488	(ABC) transporter
GZH91_RS16790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GZH91_RS16810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GZH91_RS16815	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GZH91_RS16825	COG0191	fructose-bisphosphate aldolase activity
GZH91_RS16850	COG1192	Involved in chromosome partitioning
GZH91_RS16905	COG1850	ribulose-bisphosphate carboxylase activity
GZH91_RS16920	COG3002	Belongs to the UPF0753 family
GZH91_RS16930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GZH91_RS16935	COG0628	permease
GZH91_RS16945	COG0861	Integral membrane protein TerC family
GZH91_RS16950	COG0501	Belongs to the peptidase M48B family
GZH91_RS16960	COG0670	Belongs to the BI1 family
GZH91_RS16965	COG0583	DNA-binding transcription factor activity
GZH91_RS16980	COG4451	ribulose bisphosphate carboxylase, small
GZH91_RS16985	COG1850	ribulose-bisphosphate carboxylase activity
GZH91_RS17000	COG2959	enzyme of heme biosynthesis
GZH91_RS17005	COG1587	Uroporphyrinogen-III synthase
GZH91_RS17010	COG0181	hydroxymethylbilane synthase activity
GZH91_RS17025	COG3275	phosphorelay sensor kinase activity
GZH91_RS17030	COG0165	Argininosuccinate lyase
GZH91_RS17060	COG1965	Belongs to the frataxin family
GZH91_RS17070	COG0019	diaminopimelate decarboxylase activity
GZH91_RS17080	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GZH91_RS17085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GZH91_RS17090	COG5002	protein histidine kinase activity
GZH91_RS17090	COG5001	Diguanylate cyclase
GZH91_RS17095	COG5001	Diguanylate cyclase
GZH91_RS17095	COG5002	protein histidine kinase activity
GZH91_RS17105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GZH91_RS17120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GZH91_RS17125	COG1773	rubredoxin
GZH91_RS17155	COG0753	catalase activity
GZH91_RS17165	COG0745	RESPONSE REGULATOR receiver
GZH91_RS17180	COG1131	(ABC) transporter
GZH91_RS17210	COG0671	phosphoesterase, PA-phosphatase related
GZH91_RS17225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GZH91_RS17240	COG0746	molybdenum cofactor guanylyltransferase activity
GZH91_RS17250	COG0254	rRNA binding
GZH91_RS17255	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GZH91_RS17265	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GZH91_RS17275	COG1074	ATP-dependent DNA helicase activity
GZH91_RS17285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GZH91_RS17305	COG3530	Putative quorum-sensing-regulated virulence factor
GZH91_RS17320	COG3134	Outer membrane lipoprotein
GZH91_RS17325	COG0243	molybdopterin cofactor binding
GZH91_RS17330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GZH91_RS17340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GZH91_RS17360	COG2223	nitrite transmembrane transporter activity
GZH91_RS17365	COG3039	Transposase
GZH91_RS17380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GZH91_RS17390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GZH91_RS17400	COG1116	anion transmembrane transporter activity
GZH91_RS17410	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GZH91_RS17420	COG0071	Belongs to the small heat shock protein (HSP20) family
GZH91_RS17435	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GZH91_RS17440	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GZH91_RS17445	COG3706	GGDEF domain
GZH91_RS17450	COG0756	dUTP diphosphatase activity
GZH91_RS17460	COG2003	Belongs to the UPF0758 family
GZH91_RS17465	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GZH91_RS17470	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GZH91_RS17480	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GZH91_RS17480	COG3264	Mechanosensitive ion channel
GZH91_RS17485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GZH91_RS17490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GZH91_RS17490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GZH91_RS17505	COG3260	NADH ubiquinone oxidoreductase 20
GZH91_RS17510	COG0649	NAD binding
GZH91_RS17515	COG0651	ATP synthesis coupled electron transport
GZH91_RS17525	COG0650	Formate hydrogenlyase subunit 4
GZH91_RS17530	COG0651	ATP synthesis coupled electron transport
GZH91_RS17540	COG0543	2 iron, 2 sulfur cluster binding
GZH91_RS17540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GZH91_RS17550	COG1970	mechanosensitive ion channel activity
GZH91_RS17555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GZH91_RS17560	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GZH91_RS17565	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GZH91_RS17570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GZH91_RS17575	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GZH91_RS17580	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GZH91_RS17590	COG0356	it plays a direct role in the translocation of protons across the membrane
GZH91_RS17600	COG1475	DNA binding
GZH91_RS17605	COG1192	Involved in chromosome partitioning
GZH91_RS17610	COG0357	Ribosomal RNA small subunit methyltransferase G
GZH91_RS17615	COG0445	tRNA wobble uridine modification
GZH91_RS17620	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GZH91_RS17625	COG0706	membrane insertase activity
GZH91_RS17630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GZH91_RS17635	COG0594	ribonuclease P activity
GZH91_RS17640	COG0230	Belongs to the bacterial ribosomal protein bL34 family