locus-tag	class	description
SFSGTM_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SFSGTM_RS00010	COG0592	DNA-directed DNA polymerase activity
SFSGTM_RS00045	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SFSGTM_RS00125	COG2833	Protein of unknown function (DUF455)
SFSGTM_RS00130	COG0360	Binds together with S18 to 16S ribosomal RNA
SFSGTM_RS00140	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SFSGTM_RS00145	COG0359	binds to the 23S rRNA
SFSGTM_RS00150	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
SFSGTM_RS00160	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SFSGTM_RS00165	COG1560	Kdo2-lipid A biosynthetic process
SFSGTM_RS00175	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SFSGTM_RS00180	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SFSGTM_RS00185	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SFSGTM_RS00195	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SFSGTM_RS00200	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SFSGTM_RS00205	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SFSGTM_RS00230	COG2197	response regulator
SFSGTM_RS00235	COG0300	oxidoreductase activity
SFSGTM_RS00240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SFSGTM_RS00250	COG0018	arginyl-trna synthetase
SFSGTM_RS00260	COG0792	nuclease activity
SFSGTM_RS00265	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SFSGTM_RS00270	COG2823	Periplasmic or secreted lipoprotein
SFSGTM_RS00275	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SFSGTM_RS00280	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SFSGTM_RS00305	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SFSGTM_RS00310	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
SFSGTM_RS00315	COG0415	Belongs to the DNA photolyase family
SFSGTM_RS00350	COG0411	ABC transporter
SFSGTM_RS00365	COG0683	leucine binding
SFSGTM_RS00380	COG0129	dihydroxy-acid dehydratase activity
SFSGTM_RS00385	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SFSGTM_RS00390	COG0583	DNA-binding transcription factor activity
SFSGTM_RS00395	COG1592	Rubrerythrin
SFSGTM_RS00405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SFSGTM_RS00420	COG0598	Magnesium transport protein CorA
SFSGTM_RS00435	COG2197	response regulator
SFSGTM_RS00440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SFSGTM_RS00465	COG0501	Belongs to the peptidase M48B family
SFSGTM_RS00470	COG0583	DNA-binding transcription factor activity
SFSGTM_RS00485	COG2217	Heavy metal translocating P-type atpase
SFSGTM_RS00505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SFSGTM_RS00515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SFSGTM_RS00540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SFSGTM_RS00545	COG0242	peptide deformylase activity
SFSGTM_RS00550	COG1652	LysM domain
SFSGTM_RS00555	COG0758	DNA mediated transformation
SFSGTM_RS00560	COG2922	Belongs to the Smg family
SFSGTM_RS00625	COG0254	rRNA binding
SFSGTM_RS00635	COG0746	molybdenum cofactor guanylyltransferase activity
SFSGTM_RS00640	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
SFSGTM_RS00645	COG1965	Belongs to the frataxin family
SFSGTM_RS00655	COG0019	diaminopimelate decarboxylase activity
SFSGTM_RS00665	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
SFSGTM_RS00670	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SFSGTM_RS00675	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SFSGTM_RS00680	COG2204	response regulator
SFSGTM_RS00685	COG3852	Histidine kinase
SFSGTM_RS00695	COG0174	glutamine synthetase
SFSGTM_RS00705	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SFSGTM_RS00710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SFSGTM_RS00735	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS00740	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS00765	COG3550	peptidyl-serine autophosphorylation
SFSGTM_RS00785	COG2850	peptidyl-arginine hydroxylation
SFSGTM_RS00790	COG1047	Peptidyl-prolyl cis-trans
SFSGTM_RS00795	COG0825	malonyl-CoA metabolic process
SFSGTM_RS00800	COG0037	tRNA processing
SFSGTM_RS00835	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SFSGTM_RS00840	COG0339	signal peptide processing
SFSGTM_RS00850	COG0708	Exodeoxyribonuclease III
SFSGTM_RS00865	COG0606	chelatase, subunit chli
SFSGTM_RS00870	COG2960	long-chain fatty acid transporting porin activity
SFSGTM_RS00880	COG0347	Belongs to the P(II) protein family
SFSGTM_RS00885	COG0004	ammonium transporteR
SFSGTM_RS00890	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SFSGTM_RS00910	COG0028	Belongs to the TPP enzyme family
SFSGTM_RS00925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SFSGTM_RS00955	COG1091	dTDP-4-dehydrorhamnose reductase activity
SFSGTM_RS00970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SFSGTM_RS00975	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SFSGTM_RS01025	COG4691	Plasmid stability protein
SFSGTM_RS01110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SFSGTM_RS01120	COG0675	Transposase, IS605 OrfB family
SFSGTM_RS01160	COG3549	Plasmid maintenance system killer
SFSGTM_RS01165	COG2336	PFAM SpoVT AbrB
SFSGTM_RS01170	COG2337	Toxic component of a toxin-antitoxin (TA) module
SFSGTM_RS01175	COG2944	sequence-specific DNA binding
SFSGTM_RS01270	COG0662	Cupin 2, conserved barrel domain protein
SFSGTM_RS01270	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SFSGTM_RS01305	COG0037	tRNA processing
SFSGTM_RS01310	COG1132	(ABC) transporter
SFSGTM_RS01315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SFSGTM_RS01320	COG2239	Acts as a magnesium transporter
SFSGTM_RS01325	COG3550	peptidyl-serine autophosphorylation
SFSGTM_RS01330	COG0459	protein refolding
SFSGTM_RS01335	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SFSGTM_RS01350	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
SFSGTM_RS01370	COG0352	thiamine-phosphate diphosphorylase activity
SFSGTM_RS01385	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SFSGTM_RS01395	COG0730	response to heat
SFSGTM_RS01430	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SFSGTM_RS01430	COG3264	Mechanosensitive ion channel
SFSGTM_RS01435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SFSGTM_RS01440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SFSGTM_RS01440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SFSGTM_RS01455	COG0659	secondary active sulfate transmembrane transporter activity
SFSGTM_RS01460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SFSGTM_RS01465	COG2022	thiamine diphosphate biosynthetic process
SFSGTM_RS01490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SFSGTM_RS01500	COG3258	Cytochrome c
SFSGTM_RS01520	COG4783	chaperone-mediated protein folding
SFSGTM_RS01545	COG0243	molybdopterin cofactor binding
SFSGTM_RS01550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SFSGTM_RS01560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SFSGTM_RS01585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SFSGTM_RS01590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SFSGTM_RS01595	COG1116	anion transmembrane transporter activity
SFSGTM_RS01610	COG5001	Diguanylate cyclase
SFSGTM_RS01610	COG3300	MHYT domain
SFSGTM_RS01615	COG0513	Belongs to the DEAD box helicase family
SFSGTM_RS01630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SFSGTM_RS01635	COG0251	oxidation-reduction process
SFSGTM_RS01665	COG0010	Belongs to the arginase family
SFSGTM_RS01670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SFSGTM_RS01680	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SFSGTM_RS01685	COG0174	glutamine synthetase
SFSGTM_RS01695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SFSGTM_RS01700	COG3842	ATPase activity
SFSGTM_RS01705	COG1176	ABC-type spermidine putrescine transport system, permease component I
SFSGTM_RS01710	COG1177	transmembrane transport
SFSGTM_RS01720	COG1012	belongs to the aldehyde dehydrogenase family
SFSGTM_RS01725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SFSGTM_RS01735	COG1704	LemA family
SFSGTM_RS01740	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
SFSGTM_RS01750	COG0668	transmembrane transport
SFSGTM_RS01770	COG0456	acetyltransferase
SFSGTM_RS01785	COG0642	Histidine kinase
SFSGTM_RS01815	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS01820	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS01845	COG1917	Cupin 2, conserved barrel domain protein
SFSGTM_RS01845	COG1396	sequence-specific DNA binding
SFSGTM_RS01850	COG2188	Transcriptional regulator
SFSGTM_RS01860	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
SFSGTM_RS01865	COG1053	succinate dehydrogenase
SFSGTM_RS01870	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SFSGTM_RS01875	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
SFSGTM_RS01880	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
SFSGTM_RS01905	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SFSGTM_RS01925	COG5554	nitrogen fixation
SFSGTM_RS01945	COG5554	nitrogen fixation
SFSGTM_RS01955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SFSGTM_RS01970	COG0625	glutathione transferase activity
SFSGTM_RS02005	COG0271	Belongs to the BolA IbaG family
SFSGTM_RS02010	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SFSGTM_RS02025	COG3311	Transcriptional regulator
SFSGTM_RS02050	COG4372	Transposase
SFSGTM_RS02070	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS02075	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS02120	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SFSGTM_RS02135	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SFSGTM_RS02140	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SFSGTM_RS02155	COG5420	small protein containing a coiled-coil domain
SFSGTM_RS02160	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
SFSGTM_RS02200	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SFSGTM_RS02220	COG3437	response regulator, receiver
SFSGTM_RS02230	COG4191	Histidine kinase
SFSGTM_RS02235	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
SFSGTM_RS02255	COG3411	Ferredoxin
SFSGTM_RS02260	COG0633	Ferredoxin
SFSGTM_RS02265	COG0633	Ferredoxin
SFSGTM_RS02270	COG0426	domain, Protein
SFSGTM_RS02315	COG0443	Heat shock 70 kDa protein
SFSGTM_RS02320	COG0316	Belongs to the HesB IscA family
SFSGTM_RS02325	COG0316	Belongs to the HesB IscA family
SFSGTM_RS02330	COG0822	iron-sulfur transferase activity
SFSGTM_RS02335	COG1104	cysteine desulfurase activity
SFSGTM_RS02365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SFSGTM_RS02370	COG0305	Participates in initiation and elongation during chromosome replication
SFSGTM_RS02390	COG1678	Uncharacterized ACR, COG1678
SFSGTM_RS02395	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SFSGTM_RS02400	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SFSGTM_RS02405	COG0540	Belongs to the ATCase OTCase family
SFSGTM_RS02415	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SFSGTM_RS02420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SFSGTM_RS02440	COG1136	(ABC) transporter
SFSGTM_RS02445	COG1136	(ABC) transporter
SFSGTM_RS02445	COG0577	efflux transmembrane transporter activity
SFSGTM_RS02455	COG0523	cobalamin synthesis protein
SFSGTM_RS02470	COG0811	peptide transport
SFSGTM_RS02475	COG0848	biopolymer transport protein
SFSGTM_RS02510	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SFSGTM_RS02515	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SFSGTM_RS02535	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS02540	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS02545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SFSGTM_RS02555	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SFSGTM_RS02565	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
SFSGTM_RS02585	COG0277	FAD linked oxidase domain protein
SFSGTM_RS02605	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS02610	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS02620	COG3706	GGDEF domain
SFSGTM_RS02630	COG0546	phosphoglycolate phosphatase activity
SFSGTM_RS02630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SFSGTM_RS02640	COG0697	spore germination
SFSGTM_RS02645	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SFSGTM_RS02650	COG3657	addiction module killer protein
SFSGTM_RS02655	COG0326	Molecular chaperone. Has ATPase activity
SFSGTM_RS02675	COG3781	membrane
SFSGTM_RS02690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SFSGTM_RS02695	COG0321	lipoyl(octanoyl) transferase activity
SFSGTM_RS02700	COG2921	Belongs to the UPF0250 family
SFSGTM_RS02705	COG1686	Belongs to the peptidase S11 family
SFSGTM_RS02710	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SFSGTM_RS02715	COG0772	Belongs to the SEDS family
SFSGTM_RS02720	COG0768	penicillin binding
SFSGTM_RS02725	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
SFSGTM_RS02730	COG1792	Involved in formation and maintenance of cell shape
SFSGTM_RS02735	COG1077	Cell shape determining protein MreB Mrl
SFSGTM_RS02740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SFSGTM_RS02745	COG0154	amidase activity
SFSGTM_RS02750	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SFSGTM_RS02775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SFSGTM_RS02780	COG0708	Exodeoxyribonuclease III
SFSGTM_RS02785	COG2211	Major facilitator Superfamily
SFSGTM_RS02795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SFSGTM_RS02795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SFSGTM_RS02805	COG5000	phosphorelay sensor kinase activity
SFSGTM_RS02810	COG2204	response regulator
SFSGTM_RS02810	COG2204	response regulator
SFSGTM_RS02820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SFSGTM_RS02840	COG0617	tRNA 3'-terminal CCA addition
SFSGTM_RS02845	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SFSGTM_RS02865	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
SFSGTM_RS02870	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SFSGTM_RS02880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SFSGTM_RS02885	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SFSGTM_RS02890	COG0193	aminoacyl-tRNA hydrolase activity
SFSGTM_RS02895	COG0012	GTP binding
SFSGTM_RS02915	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SFSGTM_RS02925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SFSGTM_RS02935	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SFSGTM_RS02940	COG0081	regulation of translation
SFSGTM_RS02945	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SFSGTM_RS02950	COG0222	ribosome binding
SFSGTM_RS02955	COG0085	RNA polymerase activity
SFSGTM_RS02960	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SFSGTM_RS02965	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SFSGTM_RS02970	COG0049	tRNA binding
SFSGTM_RS02975	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SFSGTM_RS02980	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SFSGTM_RS02985	COG0051	transcription antitermination factor activity, RNA binding
SFSGTM_RS02990	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SFSGTM_RS02995	COG0088	Forms part of the polypeptide exit tunnel
SFSGTM_RS03000	COG0089	rRNA binding
SFSGTM_RS03005	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SFSGTM_RS03010	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SFSGTM_RS03015	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SFSGTM_RS03020	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SFSGTM_RS03030	COG0255	Belongs to the universal ribosomal protein uL29 family
SFSGTM_RS03035	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SFSGTM_RS03040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SFSGTM_RS03045	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SFSGTM_RS03050	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SFSGTM_RS03055	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SFSGTM_RS03060	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SFSGTM_RS03065	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SFSGTM_RS03070	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SFSGTM_RS03075	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SFSGTM_RS03080	COG1841	ribosomal large subunit assembly
SFSGTM_RS03090	COG0201	protein transport
SFSGTM_RS03095	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SFSGTM_RS03100	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SFSGTM_RS03105	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SFSGTM_RS03110	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SFSGTM_RS03115	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SFSGTM_RS03120	COG0202	RNA polymerase activity
SFSGTM_RS03125	COG0203	ribosomal protein L17
SFSGTM_RS03130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SFSGTM_RS03140	COG2814	Major facilitator Superfamily
SFSGTM_RS03145	COG0629	single-stranded DNA binding
SFSGTM_RS03160	COG0513	Belongs to the DEAD box helicase family
SFSGTM_RS03175	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SFSGTM_RS03195	COG0802	atpase or kinase
SFSGTM_RS03205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SFSGTM_RS03275	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SFSGTM_RS03275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SFSGTM_RS03285	COG1696	Membrane protein involved in D-alanine export
SFSGTM_RS03300	COG0463	Glycosyl transferase, family 2
SFSGTM_RS03330	COG0438	transferase activity, transferring glycosyl groups
SFSGTM_RS03350	COG1086	Polysaccharide biosynthesis protein
SFSGTM_RS03370	COG0521	Mo-molybdopterin cofactor biosynthetic process
SFSGTM_RS03380	COG0429	hydrolase of the alpha beta-hydrolase fold
SFSGTM_RS03385	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SFSGTM_RS03390	COG0632	four-way junction helicase activity
SFSGTM_RS03395	COG2255	four-way junction helicase activity
SFSGTM_RS03400	COG0824	Thioesterase
SFSGTM_RS03420	COG0823	Involved in the tonB-independent uptake of proteins
SFSGTM_RS03435	COG0602	queuosine metabolic process
SFSGTM_RS03440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SFSGTM_RS03465	COG0702	epimerase
SFSGTM_RS03475	COG1487	ribonuclease activity
SFSGTM_RS03485	COG1162	GTPase activity
SFSGTM_RS03490	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SFSGTM_RS03535	COG0542	response to heat
SFSGTM_RS03540	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SFSGTM_RS03545	COG1278	Cold shock
SFSGTM_RS03555	COG1187	pseudouridine synthase activity
SFSGTM_RS03575	COG0482	sulfurtransferase activity
SFSGTM_RS03580	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
SFSGTM_RS03585	COG0501	Belongs to the peptidase M48B family
SFSGTM_RS03605	COG0314	molybdopterin synthase activity
SFSGTM_RS03610	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SFSGTM_RS03615	COG0303	'Molybdopterin
SFSGTM_RS03620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SFSGTM_RS03630	COG0217	transcriptional regulatory protein
SFSGTM_RS03645	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SFSGTM_RS03650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SFSGTM_RS03660	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SFSGTM_RS03665	COG1546	Belongs to the CinA family
SFSGTM_RS03670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SFSGTM_RS03675	COG2137	regulation of response to DNA damage stimulus
SFSGTM_RS03700	COG0557	exoribonuclease II activity
SFSGTM_RS03710	COG3501	Rhs element vgr protein
SFSGTM_RS03825	COG3501	Rhs element vgr protein
SFSGTM_RS03870	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SFSGTM_RS03875	COG0235	Class ii aldolase
SFSGTM_RS03880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SFSGTM_RS03885	COG0723	plastoquinol--plastocyanin reductase activity
SFSGTM_RS03890	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SFSGTM_RS03895	COG2857	Cytochrome c1
SFSGTM_RS03900	COG0625	glutathione transferase activity
SFSGTM_RS03905	COG2969	positive regulation of protein catabolic process
SFSGTM_RS03920	COG0367	asparagine synthase
SFSGTM_RS03945	COG1850	ribulose-bisphosphate carboxylase activity
SFSGTM_RS03950	COG1872	DUF167
SFSGTM_RS03955	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SFSGTM_RS03960	COG1047	Peptidyl-prolyl cis-trans
SFSGTM_RS03965	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SFSGTM_RS03970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SFSGTM_RS03975	COG0196	riboflavin kinase activity
SFSGTM_RS03985	COG0268	Binds directly to 16S ribosomal RNA
SFSGTM_RS03995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SFSGTM_RS04000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SFSGTM_RS04005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SFSGTM_RS04010	COG0137	argininosuccinate synthase activity
SFSGTM_RS04015	COG3123	guanosine phosphorylase activity
SFSGTM_RS04030	COG1666	GTP binding
SFSGTM_RS04035	COG0517	IMP dehydrogenase activity
SFSGTM_RS04040	COG0671	phosphoesterase, PA-phosphatase related
SFSGTM_RS04060	COG0277	FAD linked oxidase domain protein
SFSGTM_RS04075	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
SFSGTM_RS04080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SFSGTM_RS04095	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SFSGTM_RS04100	COG1187	pseudouridine synthase activity
SFSGTM_RS04110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SFSGTM_RS04130	COG1643	Atp-dependent helicase
SFSGTM_RS04145	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SFSGTM_RS04150	COG1420	regulation of RNA biosynthetic process
SFSGTM_RS04155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SFSGTM_RS04160	COG0497	DNA recombination
SFSGTM_RS04175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SFSGTM_RS04200	COG0513	Belongs to the DEAD box helicase family
SFSGTM_RS04215	COG1017	nitric oxide dioxygenase activity
SFSGTM_RS04215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SFSGTM_RS04220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SFSGTM_RS04230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SFSGTM_RS04235	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SFSGTM_RS04245	COG1185	polyribonucleotide nucleotidyltransferase activity
SFSGTM_RS04250	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SFSGTM_RS04255	COG1570	exodeoxyribonuclease VII activity
SFSGTM_RS04260	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SFSGTM_RS04310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SFSGTM_RS04315	COG2084	Dehydrogenase
SFSGTM_RS04330	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS04335	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS04350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SFSGTM_RS04355	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
SFSGTM_RS04360	COG1674	ftsk spoiiie
SFSGTM_RS04365	COG0492	ferredoxin-NADP+ reductase activity
SFSGTM_RS04370	COG2840	Smr protein MutS2
SFSGTM_RS04375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SFSGTM_RS04380	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SFSGTM_RS04390	COG2732	(Barnase) inhibitor
SFSGTM_RS04395	COG0446	pyridine nucleotide-disulphide oxidoreductase
SFSGTM_RS04405	COG0076	glutamate decarboxylase activity
SFSGTM_RS04420	COG0004	ammonium transporteR
SFSGTM_RS04430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SFSGTM_RS04435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SFSGTM_RS04445	COG0140	phosphoribosyl-ATP diphosphatase activity
SFSGTM_RS04450	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SFSGTM_RS04455	COG0107	imidazoleglycerol-phosphate synthase activity
SFSGTM_RS04460	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SFSGTM_RS04465	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SFSGTM_RS04470	COG0131	Imidazoleglycerol-phosphate dehydratase
SFSGTM_RS04475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SFSGTM_RS04480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SFSGTM_RS04490	COG4969	Belongs to the N-Me-Phe pilin family
SFSGTM_RS04495	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SFSGTM_RS04500	COG0450	alkyl hydroperoxide reductase
SFSGTM_RS04515	COG2076	Multidrug Resistance protein
SFSGTM_RS04520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SFSGTM_RS04525	COG0463	Glycosyl transferase, family 2
SFSGTM_RS04530	COG4269	membrane
SFSGTM_RS04540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SFSGTM_RS04540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SFSGTM_RS04545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SFSGTM_RS04545	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SFSGTM_RS04550	COG0726	polysaccharide deacetylase
SFSGTM_RS04560	COG0583	DNA-binding transcription factor activity
SFSGTM_RS04565	COG2210	Belongs to the sulfur carrier protein TusA family
SFSGTM_RS04575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SFSGTM_RS04580	COG1393	Belongs to the ArsC family
SFSGTM_RS04585	COG0735	belongs to the Fur family
SFSGTM_RS04590	COG3158	transport of potassium into the cell
SFSGTM_RS04595	COG0745	RESPONSE REGULATOR receiver
SFSGTM_RS04600	COG2205	protein histidine kinase activity
SFSGTM_RS04605	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SFSGTM_RS04610	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SFSGTM_RS04620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SFSGTM_RS04625	COG0583	DNA-binding transcription factor activity
SFSGTM_RS04655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SFSGTM_RS04660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SFSGTM_RS04675	COG1331	Highly conserved protein containing a thioredoxin domain
SFSGTM_RS04690	COG0393	Putative heavy-metal-binding
SFSGTM_RS04705	COG0500	methyltransferase
SFSGTM_RS04710	COG0789	Transcriptional regulator
SFSGTM_RS04715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SFSGTM_RS04735	COG0210	DNA helicase
SFSGTM_RS04740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SFSGTM_RS04750	COG2866	Carboxypeptidase
SFSGTM_RS04755	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SFSGTM_RS04760	COG1381	Involved in DNA repair and RecF pathway recombination
SFSGTM_RS04765	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SFSGTM_RS04775	COG0363	glucosamine-6-phosphate deaminase activity
SFSGTM_RS04780	COG1902	pentaerythritol trinitrate reductase activity
SFSGTM_RS04785	COG1741	Belongs to the pirin family
SFSGTM_RS04790	COG0583	DNA-binding transcription factor activity
SFSGTM_RS04795	COG0571	ribonuclease III activity
SFSGTM_RS04810	COG0481	GTPase activity
SFSGTM_RS04820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SFSGTM_RS04850	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
SFSGTM_RS04855	COG3647	Membrane
SFSGTM_RS04865	COG0567	Dehydrogenase, E1 component
SFSGTM_RS04870	COG0508	dehydrogenase complex catalyzes the overall conversion of
SFSGTM_RS04875	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SFSGTM_RS04880	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SFSGTM_RS04890	COG0330	HflC and HflK could
SFSGTM_RS04895	COG0330	HflC and HflK could
SFSGTM_RS04900	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SFSGTM_RS04905	COG1923	regulation of RNA biosynthetic process
SFSGTM_RS04910	COG0166	Belongs to the GPI family
SFSGTM_RS04925	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
SFSGTM_RS04945	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
SFSGTM_RS04950	COG0737	Belongs to the 5'-nucleotidase family
SFSGTM_RS04960	COG3258	Cytochrome c
SFSGTM_RS04965	COG3258	Cytochrome c
SFSGTM_RS04980	COG0737	Belongs to the 5'-nucleotidase family
SFSGTM_RS04985	COG2391	methyltransferase activity
SFSGTM_RS04990	COG2391	methyltransferase activity
SFSGTM_RS04995	COG4660	Part of a membrane complex involved in electron transport
SFSGTM_RS05010	COG4656	Part of a membrane complex involved in electron transport
SFSGTM_RS05015	COG2878	Part of a membrane complex involved in electron transport
SFSGTM_RS05025	COG4953	penicillin-binding protein 1C
SFSGTM_RS05030	COG0167	dihydroorotate dehydrogenase activity
SFSGTM_RS05040	COG0022	dehydrogenase e1 component
SFSGTM_RS05040	COG0508	dehydrogenase complex catalyzes the overall conversion of
SFSGTM_RS05045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SFSGTM_RS05050	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SFSGTM_RS05060	COG0438	transferase activity, transferring glycosyl groups
SFSGTM_RS05095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SFSGTM_RS05100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SFSGTM_RS05105	COG1530	ribonuclease E activity
SFSGTM_RS05115	COG0546	phosphoglycolate phosphatase activity
SFSGTM_RS05130	COG1595	DNA-templated transcription, initiation
SFSGTM_RS05150	COG0047	phosphoribosylformylglycinamidine synthase activity
SFSGTM_RS05150	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SFSGTM_RS05160	COG0405	Gamma-glutamyltransferase
SFSGTM_RS05205	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
SFSGTM_RS05210	COG5265	(ABC) transporter
SFSGTM_RS05215	COG0676	glucose-6-phosphate 1-epimerase activity
SFSGTM_RS05220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SFSGTM_RS05255	COG0277	FAD linked oxidase domain protein
SFSGTM_RS05260	COG0277	FAD linked oxidase domain protein
SFSGTM_RS05265	COG0247	lactate metabolic process
SFSGTM_RS05295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SFSGTM_RS05320	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SFSGTM_RS05325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SFSGTM_RS05355	COG0123	including yeast histone deacetylase and acetoin utilization protein
SFSGTM_RS05410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SFSGTM_RS05420	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
SFSGTM_RS05435	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
SFSGTM_RS05440	COG2204	response regulator
SFSGTM_RS05445	COG2205	protein histidine kinase activity
SFSGTM_RS05450	COG0045	succinate-CoA ligase (ADP-forming) activity
SFSGTM_RS05455	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SFSGTM_RS05465	COG0347	Belongs to the P(II) protein family
SFSGTM_RS05500	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS05505	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS05635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SFSGTM_RS05640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SFSGTM_RS05645	COG1116	anion transmembrane transporter activity
SFSGTM_RS05655	COG0864	Transcriptional regulator
SFSGTM_RS05660	COG3384	dioxygenase
SFSGTM_RS05670	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
SFSGTM_RS05685	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS05690	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS05700	COG3447	MASE1 domain protein
SFSGTM_RS05700	COG5001	Diguanylate cyclase
SFSGTM_RS05700	COG5002	protein histidine kinase activity
SFSGTM_RS05715	COG2814	Major facilitator Superfamily
SFSGTM_RS05720	COG1566	PFAM secretion protein HlyD family protein
SFSGTM_RS05725	COG0583	DNA-binding transcription factor activity
SFSGTM_RS05735	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS05740	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS05770	COG1566	PFAM secretion protein HlyD family protein
SFSGTM_RS05775	COG2814	Major facilitator Superfamily
SFSGTM_RS05780	COG2204	response regulator
SFSGTM_RS05785	COG4191	Histidine kinase
SFSGTM_RS05805	COG1022	Amp-dependent synthetase and ligase
SFSGTM_RS05815	COG0300	oxidoreductase activity
SFSGTM_RS05850	COG4181	ATPase activity
SFSGTM_RS05855	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
SFSGTM_RS05875	COG1214	PFAM Peptidase M22, glycoprotease
SFSGTM_RS05880	COG0456	acetyltransferase
SFSGTM_RS05905	COG0800	Aldolase
SFSGTM_RS05920	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SFSGTM_RS05925	COG2867	negative regulation of translational initiation
SFSGTM_RS05930	COG2914	Belongs to the UPF0125 (RnfH) family
SFSGTM_RS05940	COG0583	DNA-binding transcription factor activity
SFSGTM_RS05945	COG1850	ribulose-bisphosphate carboxylase activity
SFSGTM_RS05950	COG4451	ribulose bisphosphate carboxylase, small
SFSGTM_RS05975	COG0191	fructose-bisphosphate aldolase activity
SFSGTM_RS05985	COG1199	ATP-dependent helicase activity
SFSGTM_RS05990	COG0477	Major facilitator Superfamily
SFSGTM_RS06000	COG0583	DNA-binding transcription factor activity
SFSGTM_RS06015	COG0640	Transcriptional regulator
SFSGTM_RS06020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SFSGTM_RS06025	COG2197	response regulator
SFSGTM_RS06035	COG3916	Acyl-homoserine-lactone synthase
SFSGTM_RS06065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SFSGTM_RS06075	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SFSGTM_RS06075	COG0473	3-isopropylmalate dehydrogenase activity
SFSGTM_RS06080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SFSGTM_RS06080	COG0473	3-isopropylmalate dehydrogenase activity
SFSGTM_RS06090	COG1881	PFAM PEBP family protein
SFSGTM_RS06095	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SFSGTM_RS06105	COG0436	Aminotransferase
SFSGTM_RS06110	COG0556	nucleotide-excision repair
SFSGTM_RS06120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SFSGTM_RS06175	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS06180	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS06200	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS06205	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS06225	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SFSGTM_RS06230	COG3028	Belongs to the UPF0307 family
SFSGTM_RS06235	COG0312	modulator of DNA gyrase
SFSGTM_RS06250	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SFSGTM_RS06260	COG0189	ligase activity
SFSGTM_RS06280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SFSGTM_RS06285	COG0033	Phosphoglucomutase
SFSGTM_RS06300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SFSGTM_RS06300	COG0519	Catalyzes the synthesis of GMP from XMP
SFSGTM_RS06305	COG0714	Associated with various cellular activities
SFSGTM_RS06320	COG2304	oxidoreductase activity
SFSGTM_RS06325	COG2304	oxidoreductase activity
SFSGTM_RS06340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SFSGTM_RS06345	COG4178	(ABC) transporter
SFSGTM_RS06365	COG0560	Phosphoserine phosphatase
SFSGTM_RS06370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SFSGTM_RS06385	COG1028	Short-chain dehydrogenase reductase Sdr
SFSGTM_RS06415	COG4372	Transposase
SFSGTM_RS06510	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS06515	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS06530	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS06535	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS06545	COG0583	DNA-binding transcription factor activity
SFSGTM_RS06590	COG4372	Transposase
SFSGTM_RS06615	COG4372	Transposase
SFSGTM_RS06625	COG1230	cation diffusion facilitator family transporter
SFSGTM_RS06680	COG4372	Transposase
SFSGTM_RS06725	COG4372	Transposase
SFSGTM_RS06750	COG0745	RESPONSE REGULATOR receiver
SFSGTM_RS06755	COG2205	protein histidine kinase activity
SFSGTM_RS06770	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
SFSGTM_RS06775	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SFSGTM_RS06780	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SFSGTM_RS06805	COG4372	Transposase
SFSGTM_RS06835	COG4372	Transposase
SFSGTM_RS06855	COG0527	aspartate kinase activity
SFSGTM_RS06880	COG1104	cysteine desulfurase activity
SFSGTM_RS06885	COG0822	iron-sulfur transferase activity
SFSGTM_RS06895	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SFSGTM_RS06900	COG0443	Heat shock 70 kDa protein
SFSGTM_RS06910	COG2975	iron-sulfur cluster assembly
SFSGTM_RS06920	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS06925	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS06960	COG0745	RESPONSE REGULATOR receiver
SFSGTM_RS06965	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SFSGTM_RS06970	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SFSGTM_RS06980	COG2205	protein histidine kinase activity
SFSGTM_RS06990	COG2204	response regulator
SFSGTM_RS07015	COG0004	ammonium transporteR
SFSGTM_RS07025	COG0425	Belongs to the sulfur carrier protein TusA family
SFSGTM_RS07035	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS07040	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS07050	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS07055	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS07075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SFSGTM_RS07080	COG0312	modulator of DNA gyrase
SFSGTM_RS07100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SFSGTM_RS07105	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SFSGTM_RS07115	COG0586	Pfam SNARE associated Golgi protein
SFSGTM_RS07120	COG0402	S-adenosylhomocysteine deaminase activity
SFSGTM_RS07130	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SFSGTM_RS07140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SFSGTM_RS07145	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SFSGTM_RS07150	COG0287	Prephenate dehydrogenase
SFSGTM_RS07160	COG1116	anion transmembrane transporter activity
SFSGTM_RS07175	COG0439	Biotin carboxylase
SFSGTM_RS07190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SFSGTM_RS07210	COG4372	Transposase
SFSGTM_RS07220	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS07225	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS07250	COG1335	isochorismatase
SFSGTM_RS07265	COG1028	Short-chain dehydrogenase reductase Sdr
SFSGTM_RS07330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SFSGTM_RS07335	COG4548	von Willebrand factor, type A
SFSGTM_RS07340	COG0531	amino acid
SFSGTM_RS07345	COG4303	Ethanolamine ammonia lyase large subunit
SFSGTM_RS07350	COG4302	ethanolamine ammonia-lyase activity
SFSGTM_RS07355	COG3708	Transcriptional regulator
SFSGTM_RS07355	COG2207	Transcriptional regulator
SFSGTM_RS07360	COG0840	transmembrane signaling receptor activity
SFSGTM_RS07365	COG2200	EAL domain
SFSGTM_RS07365	COG2199	diguanylate cyclase activity
SFSGTM_RS07365	COG3287	FIST C domain
SFSGTM_RS07375	COG0829	nickel cation binding
SFSGTM_RS07380	COG0831	urea catabolic process
SFSGTM_RS07385	COG0832	Belongs to the urease beta subunit family
SFSGTM_RS07390	COG0804	urea catabolic process
SFSGTM_RS07395	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SFSGTM_RS07400	COG0830	nickel cation binding
SFSGTM_RS07405	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SFSGTM_RS07410	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SFSGTM_RS07415	COG0347	Belongs to the P(II) protein family
SFSGTM_RS07420	COG0004	ammonium transporteR
SFSGTM_RS07430	COG2951	lytic endotransglycosylase activity
SFSGTM_RS07475	COG4372	Transposase
SFSGTM_RS07500	COG0582	viral genome integration into host DNA
SFSGTM_RS07525	COG0156	8-amino-7-oxononanoate synthase activity
SFSGTM_RS07530	COG3321	synthase
SFSGTM_RS07530	COG1028	Short-chain dehydrogenase reductase Sdr
SFSGTM_RS07530	COG0604	alcohol dehydrogenase
SFSGTM_RS07565	COG1088	dTDP-glucose 4,6-dehydratase activity
SFSGTM_RS07570	COG0438	transferase activity, transferring glycosyl groups
SFSGTM_RS07570	COG1216	Glycosyl transferase, family 2
SFSGTM_RS07580	COG1216	Glycosyl transferase, family 2
SFSGTM_RS07580	COG0438	transferase activity, transferring glycosyl groups
SFSGTM_RS07615	COG0438	transferase activity, transferring glycosyl groups
SFSGTM_RS07660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SFSGTM_RS07670	COG0175	sulfate reduction
SFSGTM_RS07710	COG0582	viral genome integration into host DNA
SFSGTM_RS07755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SFSGTM_RS07775	COG0653	protein targeting
SFSGTM_RS07805	COG3177	Filamentation induced by cAMP protein fic
SFSGTM_RS07860	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS07865	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS07890	COG0577	efflux transmembrane transporter activity
SFSGTM_RS07890	COG1136	(ABC) transporter
SFSGTM_RS07895	COG1136	(ABC) transporter
SFSGTM_RS07895	COG0577	efflux transmembrane transporter activity
SFSGTM_RS07910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SFSGTM_RS07920	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
SFSGTM_RS07925	COG3588	fructose-bisphosphate aldolase
SFSGTM_RS07930	COG0166	Belongs to the GPI family
SFSGTM_RS07970	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS07975	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS08000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SFSGTM_RS08005	COG1127	ABC transporter
SFSGTM_RS08010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SFSGTM_RS08015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
SFSGTM_RS08035	COG1131	(ABC) transporter
SFSGTM_RS08040	COG0842	Transport permease protein
SFSGTM_RS08045	COG0271	Belongs to the BolA IbaG family
SFSGTM_RS08050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SFSGTM_RS08055	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SFSGTM_RS08065	COG0463	Glycosyl transferase, family 2
SFSGTM_RS08070	COG0438	transferase activity, transferring glycosyl groups
SFSGTM_RS08090	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS08095	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS08105	COG1215	transferase activity, transferring glycosyl groups
SFSGTM_RS08115	COG0297	glycogen (starch) synthase activity
SFSGTM_RS08120	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
SFSGTM_RS08125	COG2257	FlhB HrpN YscU SpaS Family
SFSGTM_RS08140	COG1516	flagellar protein fliS
SFSGTM_RS08145	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
SFSGTM_RS08160	COG3706	GGDEF domain
SFSGTM_RS08165	COG2197	response regulator
SFSGTM_RS08180	COG2814	Major facilitator Superfamily
SFSGTM_RS08185	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SFSGTM_RS08190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SFSGTM_RS08200	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SFSGTM_RS08230	COG4783	chaperone-mediated protein folding
SFSGTM_RS08235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SFSGTM_RS08255	COG1362	aminopeptidase activity
SFSGTM_RS08260	COG2171	N-acyltransferase activity
SFSGTM_RS08265	COG0436	Aminotransferase
SFSGTM_RS08280	COG2226	methyltransferase
SFSGTM_RS08290	COG4221	oxidoreductase activity
SFSGTM_RS08300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SFSGTM_RS08315	COG0386	Belongs to the glutathione peroxidase family
SFSGTM_RS08325	COG0123	including yeast histone deacetylase and acetoin utilization protein
SFSGTM_RS08330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SFSGTM_RS08330	COG1042	CoA-binding domain protein
SFSGTM_RS08330	COG0045	succinate-CoA ligase (ADP-forming) activity
SFSGTM_RS08335	COG2226	methyltransferase
SFSGTM_RS08340	COG0842	Transport permease protein
SFSGTM_RS08350	COG0842	Transport permease protein
SFSGTM_RS08355	COG1131	(ABC) transporter
SFSGTM_RS08365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SFSGTM_RS08390	COG5002	protein histidine kinase activity
SFSGTM_RS08390	COG5001	Diguanylate cyclase
SFSGTM_RS08405	COG1722	exodeoxyribonuclease VII activity
SFSGTM_RS08410	COG0142	geranyltranstransferase activity
SFSGTM_RS08415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SFSGTM_RS08420	COG1469	GTP cyclohydrolase I activity
SFSGTM_RS08425	COG0505	Belongs to the CarA family
SFSGTM_RS08460	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS08465	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS08470	COG0243	molybdopterin cofactor binding
SFSGTM_RS08480	COG0776	regulation of translation
SFSGTM_RS08495	COG0402	S-adenosylhomocysteine deaminase activity
SFSGTM_RS08525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
SFSGTM_RS08535	COG2351	hydroxyisourate hydrolase activity
SFSGTM_RS08540	COG0402	S-adenosylhomocysteine deaminase activity
SFSGTM_RS08545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SFSGTM_RS08565	COG3195	allantoin biosynthetic process
SFSGTM_RS08565	COG3648	Uricase
SFSGTM_RS08570	COG4266	Belongs to the allantoicase family
SFSGTM_RS08575	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
SFSGTM_RS08580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SFSGTM_RS08585	COG2258	MOSC domain
SFSGTM_RS08590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SFSGTM_RS08600	COG2132	Multicopper oxidase
SFSGTM_RS08610	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
SFSGTM_RS08685	COG0069	glutamate synthase activity
SFSGTM_RS08690	COG2218	PFAM glutamate synthase alpha subunit domain protein
SFSGTM_RS08695	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SFSGTM_RS08710	COG0446	pyridine nucleotide-disulphide oxidoreductase
SFSGTM_RS08710	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SFSGTM_RS08725	COG0788	formyltetrahydrofolate deformylase activity
SFSGTM_RS08755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SFSGTM_RS08760	COG0438	transferase activity, transferring glycosyl groups
SFSGTM_RS08765	COG3100	YcgL domain-containing protein
SFSGTM_RS08765	COG0561	phosphatase activity
SFSGTM_RS08775	COG0668	transmembrane transport
SFSGTM_RS08790	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SFSGTM_RS08805	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SFSGTM_RS08810	COG2183	response to ionizing radiation
SFSGTM_RS08825	COG2353	YceI-like domain
SFSGTM_RS08830	COG2353	YceI-like domain
SFSGTM_RS08835	COG3038	cytochrome b561
SFSGTM_RS08840	COG1846	Transcriptional regulator
SFSGTM_RS08845	COG0574	Belongs to the PEP-utilizing enzyme family
SFSGTM_RS08845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SFSGTM_RS08850	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SFSGTM_RS08890	COG4372	Transposase
SFSGTM_RS08925	COG4372	Transposase
SFSGTM_RS08940	COG4372	Transposase
SFSGTM_RS08950	COG1070	Carbohydrate kinase
SFSGTM_RS08960	COG0180	Tryptophanyl-tRNA synthetase
SFSGTM_RS08965	COG1994	Peptidase M50
SFSGTM_RS08970	COG0009	L-threonylcarbamoyladenylate synthase
SFSGTM_RS08975	COG0613	PHP domain protein
SFSGTM_RS08985	COG2917	probably involved in intracellular septation
SFSGTM_RS08990	COG2350	Protein conserved in bacteria
SFSGTM_RS09000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SFSGTM_RS09005	COG1923	regulation of RNA biosynthetic process
SFSGTM_RS09010	COG0308	aminopeptidase N
SFSGTM_RS09015	COG4172	Belongs to the ABC transporter superfamily
SFSGTM_RS09020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SFSGTM_RS09040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SFSGTM_RS09060	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SFSGTM_RS09065	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SFSGTM_RS09070	COG0740	serine-type endopeptidase activity
SFSGTM_RS09075	COG0544	peptidyl-prolyl cis-trans isomerase activity
SFSGTM_RS09095	COG0123	including yeast histone deacetylase and acetoin utilization protein
SFSGTM_RS09125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SFSGTM_RS09130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SFSGTM_RS09135	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS09140	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS09160	COG1562	ergosterol biosynthetic process
SFSGTM_RS09170	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SFSGTM_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
SFSGTM_RS09180	COG1566	PFAM secretion protein HlyD family protein
SFSGTM_RS09195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SFSGTM_RS09200	COG1027	Aspartate ammonia-lyase
SFSGTM_RS09220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SFSGTM_RS09235	COG2326	polyphosphate kinase activity
SFSGTM_RS09240	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SFSGTM_RS09245	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SFSGTM_RS09250	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SFSGTM_RS09260	COG0356	it plays a direct role in the translocation of protons across the membrane
SFSGTM_RS09280	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SFSGTM_RS09320	COG1295	ribonuclease BN
SFSGTM_RS09320	COG1959	2 iron, 2 sulfur cluster binding
SFSGTM_RS09335	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SFSGTM_RS09350	COG2059	Chromate
SFSGTM_RS09360	COG2826	transposase and inactivated derivatives, IS30 family
SFSGTM_RS09365	COG0450	alkyl hydroperoxide reductase
SFSGTM_RS09375	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SFSGTM_RS09380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SFSGTM_RS09385	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SFSGTM_RS09390	COG0443	Heat shock 70 kDa protein
SFSGTM_RS09395	COG0484	heat shock protein binding
SFSGTM_RS09410	COG0084	hydrolase, TatD family'
SFSGTM_RS09425	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SFSGTM_RS09430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SFSGTM_RS09435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SFSGTM_RS09440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SFSGTM_RS09445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SFSGTM_RS09450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SFSGTM_RS09455	COG1028	Short-chain dehydrogenase reductase Sdr
SFSGTM_RS09460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SFSGTM_RS09470	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SFSGTM_RS09480	COG0439	Biotin carboxylase
SFSGTM_RS09485	COG5016	pyruvate
SFSGTM_RS09485	COG0511	ligase activity, forming carbon-carbon bonds
SFSGTM_RS09490	COG0424	maF-like protein
SFSGTM_RS09500	COG0328	RNA-DNA hybrid ribonuclease activity
SFSGTM_RS09505	COG2226	methyltransferase
SFSGTM_RS09510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SFSGTM_RS09515	COG0741	lytic transglycosylase activity
SFSGTM_RS09515	COG1388	LysM domain
SFSGTM_RS09525	COG1193	negative regulation of DNA recombination
SFSGTM_RS09535	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SFSGTM_RS09555	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SFSGTM_RS09575	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SFSGTM_RS09595	COG0776	regulation of translation
SFSGTM_RS09605	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SFSGTM_RS09610	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SFSGTM_RS09625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SFSGTM_RS09650	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS09655	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS09665	COG1715	Restriction endonuclease
SFSGTM_RS09680	COG3660	Nucleoside-diphosphate-sugar epimerase
SFSGTM_RS09690	COG0688	phosphatidylethanolamine metabolic process
SFSGTM_RS09700	COG5001	Diguanylate cyclase
SFSGTM_RS09700	COG5002	protein histidine kinase activity
SFSGTM_RS09700	COG3447	MASE1 domain protein
SFSGTM_RS09710	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SFSGTM_RS09715	COG0409	Hydrogenase expression formation protein
SFSGTM_RS09725	COG0375	protein maturation
SFSGTM_RS09730	COG0298	carbon dioxide binding
SFSGTM_RS09760	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SFSGTM_RS09765	COG2200	EAL domain
SFSGTM_RS09765	COG2199	diguanylate cyclase activity
SFSGTM_RS09765	COG3287	FIST C domain
SFSGTM_RS09770	COG0542	response to heat
SFSGTM_RS09815	COG0123	including yeast histone deacetylase and acetoin utilization protein
SFSGTM_RS09820	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SFSGTM_RS09825	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SFSGTM_RS09830	COG1763	Mo-molybdopterin cofactor biosynthetic process
SFSGTM_RS09835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SFSGTM_RS09840	COG2081	HI0933 family
SFSGTM_RS09845	COG1187	pseudouridine synthase activity
SFSGTM_RS09850	COG1944	ATP diphosphatase activity
SFSGTM_RS09890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SFSGTM_RS09910	COG1317	bacterial-type flagellum organization
SFSGTM_RS09915	COG1157	protein secretion by the type III secretion system
SFSGTM_RS09940	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SFSGTM_RS09955	COG1987	bacterial-type flagellum assembly
SFSGTM_RS09970	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
SFSGTM_RS09975	COG0745	RESPONSE REGULATOR receiver
SFSGTM_RS09980	COG2201	protein-glutamate methylesterase activity
SFSGTM_RS09985	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
SFSGTM_RS09990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SFSGTM_RS09995	COG0840	transmembrane signaling receptor activity
SFSGTM_RS10000	COG0784	Response regulator, receiver
SFSGTM_RS10000	COG0835	chemotaxis
SFSGTM_RS10005	COG0840	transmembrane signaling receptor activity
SFSGTM_RS10015	COG0840	transmembrane signaling receptor activity
SFSGTM_RS10020	COG0835	chemotaxis
SFSGTM_RS10025	COG2198	Histidine kinase
SFSGTM_RS10025	COG0643	Histidine kinase
SFSGTM_RS10035	COG1256	bacterial-type flagellum assembly
SFSGTM_RS10045	COG1706	bacterial-type flagellum-dependent cell motility
SFSGTM_RS10050	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
SFSGTM_RS10060	COG4787	bacterial-type flagellum-dependent cell motility
SFSGTM_RS10070	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SFSGTM_RS10075	COG1558	bacterial-type flagellum-dependent cell motility
SFSGTM_RS10080	COG1815	bacterial-type flagellum-dependent cell motility
SFSGTM_RS10100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SFSGTM_RS10115	COG0564	pseudouridine synthase activity
SFSGTM_RS10135	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SFSGTM_RS10140	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SFSGTM_RS10145	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SFSGTM_RS10155	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SFSGTM_RS10170	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SFSGTM_RS10185	COG0494	nUDIX hydrolase
SFSGTM_RS10195	COG0058	SHG alpha-glucan phosphorylase activity
SFSGTM_RS10200	COG0297	glycogen (starch) synthase activity
SFSGTM_RS10205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SFSGTM_RS10220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SFSGTM_RS10225	COG0837	glucose binding
SFSGTM_RS10235	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SFSGTM_RS10240	COG0811	peptide transport
SFSGTM_RS10245	COG0848	biopolymer transport protein
SFSGTM_RS10255	COG1663	tetraacyldisaccharide 4'-kinase activity
SFSGTM_RS10260	COG2835	tetraacyldisaccharide 4'-kinase activity
SFSGTM_RS10265	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SFSGTM_RS10270	COG0563	adenylate kinase activity
SFSGTM_RS10275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SFSGTM_RS10285	COG0670	Belongs to the BI1 family
SFSGTM_RS10290	COG2890	protein-(glutamine-N5) methyltransferase activity
SFSGTM_RS10295	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SFSGTM_RS10300	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SFSGTM_RS10310	COG0408	coproporphyrinogen oxidase activity
SFSGTM_RS10315	COG0009	L-threonylcarbamoyladenylate synthase
SFSGTM_RS10320	COG0151	Belongs to the GarS family
SFSGTM_RS10325	COG0138	bifunctional purine biosynthesis protein purh
SFSGTM_RS10330	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
SFSGTM_RS10365	COG4774	siderophore transport
SFSGTM_RS10370	COG3128	pkhd-type hydroxylase
SFSGTM_RS10395	COG0659	secondary active sulfate transmembrane transporter activity
SFSGTM_RS10410	COG0795	lipopolysaccharide-transporting ATPase activity
SFSGTM_RS10415	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SFSGTM_RS10445	COG0525	valine-tRNA ligase activity
SFSGTM_RS10460	COG3263	regulation of cellular component size
SFSGTM_RS10465	COG2863	cytochrome
SFSGTM_RS10470	COG3258	Cytochrome c
SFSGTM_RS10490	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS10495	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS10540	COG2982	Protein involved in outer membrane biogenesis
SFSGTM_RS10550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SFSGTM_RS10550	COG4499	WXG100 protein secretion system (Wss), protein YukC
SFSGTM_RS10585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SFSGTM_RS10590	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SFSGTM_RS10595	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SFSGTM_RS10600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SFSGTM_RS10605	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SFSGTM_RS10625	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SFSGTM_RS10630	COG0575	Belongs to the CDS family
SFSGTM_RS10635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SFSGTM_RS10640	COG0233	cytoplasmic translational termination
SFSGTM_RS10645	COG0528	UMP kinase activity
SFSGTM_RS10650	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SFSGTM_RS10655	COG0052	Belongs to the universal ribosomal protein uS2 family
SFSGTM_RS10660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SFSGTM_RS10665	COG3568	Endonuclease Exonuclease Phosphatase
SFSGTM_RS10670	COG2202	Pas domain
SFSGTM_RS10670	COG2200	EAL domain
SFSGTM_RS10670	COG2199	diguanylate cyclase activity
SFSGTM_RS10680	COG1459	type II secretion system
SFSGTM_RS10745	COG3267	Type II secretory pathway component ExeA
SFSGTM_RS10745	COG3409	Peptidoglycan-binding domain 1 protein
SFSGTM_RS10755	COG0488	(ABC) transporter
SFSGTM_RS10770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SFSGTM_RS10780	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SFSGTM_RS10790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SFSGTM_RS10790	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SFSGTM_RS10795	COG1752	Esterase of the alpha-beta hydrolase superfamily
SFSGTM_RS10830	COG0667	Aldo Keto reductase
SFSGTM_RS10850	COG1215	transferase activity, transferring glycosyl groups
SFSGTM_RS10885	COG1132	(ABC) transporter
SFSGTM_RS10890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SFSGTM_RS10890	COG0189	ligase activity
SFSGTM_RS10895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SFSGTM_RS10895	COG0189	ligase activity
SFSGTM_RS10900	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SFSGTM_RS10905	COG0433	COG0433 Predicted ATPase
SFSGTM_RS10925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SFSGTM_RS10930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SFSGTM_RS10940	COG1846	Transcriptional regulator
SFSGTM_RS10950	COG1704	LemA family
SFSGTM_RS10965	COG2200	EAL domain
SFSGTM_RS10965	COG2199	diguanylate cyclase activity
SFSGTM_RS10965	COG3287	FIST C domain
SFSGTM_RS10975	COG1982	Orn Lys Arg decarboxylase major
SFSGTM_RS10980	COG0717	Belongs to the dCTP deaminase family
SFSGTM_RS10985	COG0489	protein tyrosine kinase activity
SFSGTM_RS10995	COG0494	nUDIX hydrolase
SFSGTM_RS11010	COG0788	formyltetrahydrofolate deformylase activity
SFSGTM_RS11035	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
SFSGTM_RS11040	COG0281	malic enzyme
SFSGTM_RS11055	COG4628	conserved protein (DUF2132)
SFSGTM_RS11060	COG4807	Protein conserved in bacteria
SFSGTM_RS11065	COG0514	ATP-dependent DNA helicase (RecQ)
SFSGTM_RS11070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SFSGTM_RS11075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SFSGTM_RS11115	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SFSGTM_RS11125	COG3437	response regulator, receiver
SFSGTM_RS11130	COG2205	protein histidine kinase activity
SFSGTM_RS11130	COG4999	Histidine kinase
SFSGTM_RS11130	COG3850	Histidine kinase
SFSGTM_RS11130	COG3437	response regulator, receiver
SFSGTM_RS11135	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
SFSGTM_RS11140	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
SFSGTM_RS11145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SFSGTM_RS11155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SFSGTM_RS11160	COG0343	queuine tRNA-ribosyltransferase activity
SFSGTM_RS11165	COG1862	Preprotein translocase
SFSGTM_RS11170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SFSGTM_RS11175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SFSGTM_RS11180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SFSGTM_RS11185	COG0546	phosphoglycolate phosphatase activity
SFSGTM_RS11195	COG0582	viral genome integration into host DNA
SFSGTM_RS11230	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS11235	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS11265	COG0837	glucose binding
SFSGTM_RS11275	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SFSGTM_RS11280	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SFSGTM_RS11285	COG0509	glycine decarboxylation via glycine cleavage system
SFSGTM_RS11290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SFSGTM_RS11305	COG1136	(ABC) transporter
SFSGTM_RS11320	COG0791	NLP P60 protein
SFSGTM_RS11335	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SFSGTM_RS11340	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SFSGTM_RS11345	COG0446	pyridine nucleotide-disulphide oxidoreductase
SFSGTM_RS11355	COG2346	COG2346, Truncated hemoglobins
SFSGTM_RS11375	COG1294	oxidase, subunit
SFSGTM_RS11405	COG4771	TonB-dependent receptor
SFSGTM_RS11415	COG1730	sister chromatid segregation
SFSGTM_RS11465	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS11470	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS11475	COG3237	CsbD-like
SFSGTM_RS11520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SFSGTM_RS11525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SFSGTM_RS11535	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SFSGTM_RS11535	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SFSGTM_RS11540	COG0354	folic acid binding
SFSGTM_RS11550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SFSGTM_RS11555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SFSGTM_RS11560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SFSGTM_RS11560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SFSGTM_RS11585	COG0142	geranyltranstransferase activity
SFSGTM_RS11590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SFSGTM_RS11595	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SFSGTM_RS11600	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SFSGTM_RS11605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SFSGTM_RS11610	COG0741	lytic transglycosylase activity
SFSGTM_RS11615	COG0442	prolyl-tRNA aminoacylation
SFSGTM_RS11620	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SFSGTM_RS11635	COG0495	leucyl-tRNA aminoacylation
SFSGTM_RS11640	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
SFSGTM_RS11655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SFSGTM_RS11660	COG3038	cytochrome b561
SFSGTM_RS11675	COG0335	large ribosomal subunit rRNA binding
SFSGTM_RS11680	COG0336	Belongs to the RNA methyltransferase TrmD family
SFSGTM_RS11685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SFSGTM_RS11690	COG0228	four-way junction DNA binding
SFSGTM_RS11695	COG0024	Methionine aminopeptidase
SFSGTM_RS11700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SFSGTM_RS11705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SFSGTM_RS11710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SFSGTM_RS11720	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
SFSGTM_RS11725	COG0148	phosphopyruvate hydratase activity
SFSGTM_RS11730	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SFSGTM_RS11735	COG0504	CTP synthase activity
SFSGTM_RS11740	COG5001	Diguanylate cyclase
SFSGTM_RS11740	COG5002	protein histidine kinase activity
SFSGTM_RS11745	COG0784	Response regulator, receiver
SFSGTM_RS11750	COG4251	negative regulation of phosphorylation
SFSGTM_RS11775	COG2226	methyltransferase
SFSGTM_RS11785	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SFSGTM_RS11790	COG0697	spore germination
SFSGTM_RS11795	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SFSGTM_RS11800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SFSGTM_RS11805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SFSGTM_RS11870	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS11875	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS11900	COG4372	Transposase
SFSGTM_RS11940	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SFSGTM_RS11945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SFSGTM_RS11955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SFSGTM_RS11975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SFSGTM_RS11985	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SFSGTM_RS12030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SFSGTM_RS12035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SFSGTM_RS12035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SFSGTM_RS12055	COG4372	Transposase
SFSGTM_RS12120	COG3501	Rhs element vgr protein
SFSGTM_RS12135	COG1388	LysM domain
SFSGTM_RS12135	COG1705	Flagellar rod assembly protein muramidase FlgJ
SFSGTM_RS12140	COG3501	Rhs element vgr protein
SFSGTM_RS12200	COG3501	Rhs element vgr protein
SFSGTM_RS12220	COG3501	Rhs element vgr protein
SFSGTM_RS12240	COG3501	Rhs element vgr protein
SFSGTM_RS12295	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS12300	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS12305	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SFSGTM_RS12310	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
SFSGTM_RS12315	COG0625	glutathione transferase activity
SFSGTM_RS12330	COG0436	Aminotransferase
SFSGTM_RS12340	COG1011	Hydrolase
SFSGTM_RS12345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SFSGTM_RS12355	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SFSGTM_RS12360	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SFSGTM_RS12380	COG0776	regulation of translation
SFSGTM_RS12385	COG0072	phenylalanine-tRNA ligase activity
SFSGTM_RS12385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SFSGTM_RS12390	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SFSGTM_RS12395	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SFSGTM_RS12400	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SFSGTM_RS12405	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SFSGTM_RS12410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SFSGTM_RS12420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SFSGTM_RS12425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SFSGTM_RS12465	COG0477	Major facilitator Superfamily
SFSGTM_RS12470	COG0204	Acyl-transferase
SFSGTM_RS12470	COG0318	PFAM AMP-dependent synthetase and ligase
SFSGTM_RS12480	COG0513	Belongs to the DEAD box helicase family
SFSGTM_RS12490	COG0105	UTP biosynthetic process
SFSGTM_RS12495	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SFSGTM_RS12510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SFSGTM_RS12515	COG0124	histidyl-tRNA synthetase
SFSGTM_RS12525	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SFSGTM_RS12530	COG1160	GTP binding
SFSGTM_RS12540	COG0330	HflC and HflK could
SFSGTM_RS12575	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SFSGTM_RS12580	COG2715	membrane protein required for spore maturation
SFSGTM_RS12585	COG0248	Ppx GppA phosphatase
SFSGTM_RS12595	COG4681	YaeQ
SFSGTM_RS12625	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SFSGTM_RS12655	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SFSGTM_RS12660	COG4942	peptidase
SFSGTM_RS12665	COG0793	Belongs to the peptidase S41A family
SFSGTM_RS12680	COG0642	Histidine kinase
SFSGTM_RS12685	COG0745	RESPONSE REGULATOR receiver
SFSGTM_RS12700	COG0811	peptide transport
SFSGTM_RS12705	COG0848	biopolymer transport protein
SFSGTM_RS12720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SFSGTM_RS12725	COG1183	phosphatidylcholine synthase activity
SFSGTM_RS12730	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SFSGTM_RS12740	COG0028	Belongs to the TPP enzyme family
SFSGTM_RS12745	COG4783	chaperone-mediated protein folding
SFSGTM_RS12765	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SFSGTM_RS12800	COG2200	EAL domain
SFSGTM_RS12805	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
SFSGTM_RS12810	COG2925	Exonuclease
SFSGTM_RS12820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SFSGTM_RS12825	COG2095	MarC family integral membrane protein
SFSGTM_RS12830	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
SFSGTM_RS12835	COG0215	cysteine-tRNA ligase activity
SFSGTM_RS12850	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SFSGTM_RS12855	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SFSGTM_RS12860	COG3304	Inner membrane component domain
SFSGTM_RS12880	COG1286	toxin biosynthetic process
SFSGTM_RS12890	COG0285	dihydrofolate synthase activity
SFSGTM_RS12895	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SFSGTM_RS12900	COG0159	tryptophan synthase activity
SFSGTM_RS12905	COG0133	tryptophan synthase activity
SFSGTM_RS12910	COG0135	phosphoribosylanthranilate isomerase activity
SFSGTM_RS12915	COG0101	tRNA pseudouridine synthase activity
SFSGTM_RS12930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SFSGTM_RS12940	COG0473	3-isopropylmalate dehydrogenase activity
SFSGTM_RS12945	COG0066	3-isopropylmalate dehydratase activity
SFSGTM_RS12950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SFSGTM_RS12955	COG2814	Major facilitator Superfamily
SFSGTM_RS12960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SFSGTM_RS12970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SFSGTM_RS12990	COG1007	ATP synthesis coupled electron transport
SFSGTM_RS13005	COG0713	ATP synthesis coupled electron transport
SFSGTM_RS13015	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SFSGTM_RS13020	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SFSGTM_RS13025	COG1034	ATP synthesis coupled electron transport
SFSGTM_RS13040	COG0649	NAD binding
SFSGTM_RS13045	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SFSGTM_RS13050	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SFSGTM_RS13055	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SFSGTM_RS13065	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SFSGTM_RS13070	COG0149	triose-phosphate isomerase activity
SFSGTM_RS13080	COG0573	inorganic phosphate transmembrane transporter activity
SFSGTM_RS13090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SFSGTM_RS13095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SFSGTM_RS13100	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SFSGTM_RS13105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SFSGTM_RS13110	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
SFSGTM_RS13130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SFSGTM_RS13135	COG0505	Belongs to the CarA family
SFSGTM_RS13150	COG0387	Pfam Sodium calcium exchanger
SFSGTM_RS13160	COG1132	(ABC) transporter
SFSGTM_RS13190	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS13195	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS13210	COG0242	peptide deformylase activity
SFSGTM_RS13215	COG3158	transport of potassium into the cell
SFSGTM_RS13230	COG0322	excinuclease ABC activity
SFSGTM_RS13235	COG1573	uracil-dna glycosylase
SFSGTM_RS13240	COG1472	Belongs to the glycosyl hydrolase 3 family
SFSGTM_RS13245	COG0736	holo-[acyl-carrier-protein] synthase activity
SFSGTM_RS13270	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SFSGTM_RS13275	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SFSGTM_RS13280	COG3064	Membrane
SFSGTM_RS13280	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SFSGTM_RS13285	COG2251	uridine kinase activity
SFSGTM_RS13285	COG0195	Participates in both transcription termination and antitermination
SFSGTM_RS13290	COG0779	Required for maturation of 30S ribosomal subunits
SFSGTM_RS13315	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SFSGTM_RS13340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SFSGTM_RS13345	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SFSGTM_RS13350	COG0799	negative regulation of ribosome biogenesis
SFSGTM_RS13355	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SFSGTM_RS13360	COG0424	maF-like protein
SFSGTM_RS13365	COG1530	ribonuclease E activity
SFSGTM_RS13380	COG0762	integral membrane protein
SFSGTM_RS13415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SFSGTM_RS13440	COG2308	Evidence 4 Homologs of previously reported genes of
SFSGTM_RS13465	COG0277	FAD linked oxidase domain protein
SFSGTM_RS13470	COG2046	Belongs to the sulfate adenylyltransferase family
SFSGTM_RS13475	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SFSGTM_RS13520	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SFSGTM_RS13530	COG1333	cytochrome c biogenesis protein
SFSGTM_RS13535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SFSGTM_RS13540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SFSGTM_RS13545	COG0352	thiamine-phosphate diphosphorylase activity
SFSGTM_RS13555	COG1773	rubredoxin
SFSGTM_RS13580	COG0643	Histidine kinase
SFSGTM_RS13580	COG2198	Histidine kinase
SFSGTM_RS13585	COG3437	response regulator, receiver
SFSGTM_RS13590	COG0784	Response regulator, receiver
SFSGTM_RS13590	COG2198	Histidine kinase
SFSGTM_RS13590	COG5002	protein histidine kinase activity
SFSGTM_RS13595	COG1968	undecaprenyl-diphosphatase activity
SFSGTM_RS13600	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SFSGTM_RS13605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
SFSGTM_RS13610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SFSGTM_RS13640	COG1519	Transferase
SFSGTM_RS13675	COG0628	permease
SFSGTM_RS13730	COG0653	protein targeting
SFSGTM_RS13745	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SFSGTM_RS13760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SFSGTM_RS13765	COG1181	Belongs to the D-alanine--D-alanine ligase family
SFSGTM_RS13770	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SFSGTM_RS13775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SFSGTM_RS13780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SFSGTM_RS13785	COG0772	Belongs to the SEDS family
SFSGTM_RS13790	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SFSGTM_RS13795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SFSGTM_RS13800	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SFSGTM_RS13805	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SFSGTM_RS13815	COG3116	cell division
SFSGTM_RS13820	COG0275	rRNA processing
SFSGTM_RS13825	COG2001	Belongs to the MraZ family
SFSGTM_RS13845	COG2967	ApaG domain
SFSGTM_RS13850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SFSGTM_RS13855	COG0546	phosphoglycolate phosphatase activity
SFSGTM_RS13870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SFSGTM_RS13875	COG0134	indole-3-glycerol-phosphate synthase activity
SFSGTM_RS13890	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS13895	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS13905	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
SFSGTM_RS13915	COG0745	RESPONSE REGULATOR receiver
SFSGTM_RS13930	COG0752	glycyl-tRNA synthetase alpha subunit
SFSGTM_RS13950	COG1074	ATP-dependent DNA helicase activity
SFSGTM_RS13965	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SFSGTM_RS13970	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SFSGTM_RS13975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SFSGTM_RS13980	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
SFSGTM_RS13990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SFSGTM_RS14000	COG0006	proline dipeptidase activity
SFSGTM_RS14005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SFSGTM_RS14010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SFSGTM_RS14015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SFSGTM_RS14025	COG5002	protein histidine kinase activity
SFSGTM_RS14025	COG5001	Diguanylate cyclase
SFSGTM_RS14030	COG5002	protein histidine kinase activity
SFSGTM_RS14030	COG5001	Diguanylate cyclase
SFSGTM_RS14040	COG2824	Alkylphosphonate utilization operon protein PhnA
SFSGTM_RS14060	COG0095	Lipoate-protein ligase
SFSGTM_RS14070	COG0509	glycine decarboxylation via glycine cleavage system
SFSGTM_RS14080	COG0509	glycine decarboxylation via glycine cleavage system
SFSGTM_RS14085	COG2048	Heterodisulfide reductase, subunit B
SFSGTM_RS14115	COG2210	Belongs to the sulfur carrier protein TusA family
SFSGTM_RS14120	COG0425	Belongs to the sulfur carrier protein TusA family
SFSGTM_RS14130	COG3302	dmso reductase anchor subunit
SFSGTM_RS14135	COG0437	4 iron, 4 sulfur cluster binding
SFSGTM_RS14140	COG0243	molybdopterin cofactor binding
SFSGTM_RS14155	COG4536	flavin adenine dinucleotide binding
SFSGTM_RS14170	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SFSGTM_RS14175	COG0237	dephospho-CoA kinase activity
SFSGTM_RS14180	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
SFSGTM_RS14185	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
SFSGTM_RS14190	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SFSGTM_RS14195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SFSGTM_RS14200	COG0741	lytic transglycosylase activity
SFSGTM_RS14215	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SFSGTM_RS14220	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
SFSGTM_RS14240	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SFSGTM_RS14245	COG2226	methyltransferase
SFSGTM_RS14250	COG2267	carboxylic ester hydrolase activity
SFSGTM_RS14255	COG0156	8-amino-7-oxononanoate synthase activity
SFSGTM_RS14260	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SFSGTM_RS14275	COG0642	Histidine kinase
SFSGTM_RS14300	COG0165	Argininosuccinate lyase
SFSGTM_RS14305	COG3275	phosphorelay sensor kinase activity
SFSGTM_RS14320	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SFSGTM_RS14325	COG1116	anion transmembrane transporter activity
SFSGTM_RS14330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SFSGTM_RS14335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SFSGTM_RS14370	COG0181	hydroxymethylbilane synthase activity
SFSGTM_RS14375	COG1587	Uroporphyrinogen-III synthase
SFSGTM_RS14380	COG2959	enzyme of heme biosynthesis
SFSGTM_RS14400	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS14405	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS14415	COG0504	CTP synthase activity
SFSGTM_RS14450	COG3459	Glycosyltransferase 36 associated
SFSGTM_RS14470	COG4372	Transposase
SFSGTM_RS14480	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SFSGTM_RS14505	COG4372	Transposase
SFSGTM_RS14520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SFSGTM_RS14525	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
SFSGTM_RS14530	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SFSGTM_RS14550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SFSGTM_RS14600	COG2808	Putative FMN-binding domain
SFSGTM_RS14605	COG0418	dihydroorotase activity
SFSGTM_RS14610	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SFSGTM_RS14615	COG5001	Diguanylate cyclase
SFSGTM_RS14615	COG5002	protein histidine kinase activity
SFSGTM_RS14635	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SFSGTM_RS14640	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SFSGTM_RS14645	COG2003	Belongs to the UPF0758 family
SFSGTM_RS14650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SFSGTM_RS14655	COG0756	dUTP diphosphatase activity
SFSGTM_RS14665	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SFSGTM_RS14670	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SFSGTM_RS14690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SFSGTM_RS14700	COG2198	Histidine kinase
SFSGTM_RS14700	COG0643	Histidine kinase
SFSGTM_RS14705	COG0835	chemotaxis
SFSGTM_RS14710	COG0840	transmembrane signaling receptor activity
SFSGTM_RS14715	COG0835	chemotaxis
SFSGTM_RS14715	COG0784	Response regulator, receiver
SFSGTM_RS14720	COG0840	transmembrane signaling receptor activity
SFSGTM_RS14725	COG0745	RESPONSE REGULATOR receiver
SFSGTM_RS14730	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
SFSGTM_RS14770	COG1459	type II secretion system
SFSGTM_RS14790	COG0400	carboxylic ester hydrolase activity
SFSGTM_RS14795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SFSGTM_RS14800	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SFSGTM_RS14805	COG0742	ribosomal rna small subunit methyltransferase
SFSGTM_RS14810	COG0612	Peptidase, M16
SFSGTM_RS14815	COG0612	Peptidase, M16
SFSGTM_RS14825	COG2884	Cell division ATP-binding protein ftsE
SFSGTM_RS14830	COG2177	Part of the ABC transporter FtsEX involved in
SFSGTM_RS14845	COG2217	Heavy metal translocating P-type atpase
SFSGTM_RS14855	COG0348	domain, Protein
SFSGTM_RS14860	COG2010	Cytochrome c
SFSGTM_RS14875	COG3278	Belongs to the heme-copper respiratory oxidase family
SFSGTM_RS14880	COG1999	signal sequence binding
SFSGTM_RS14885	COG1959	2 iron, 2 sulfur cluster binding
SFSGTM_RS14890	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SFSGTM_RS14895	COG3161	chorismate lyase activity
SFSGTM_RS14905	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SFSGTM_RS14920	COG1686	Belongs to the peptidase S11 family
SFSGTM_RS14925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SFSGTM_RS14930	COG1758	RNA polymerase activity
SFSGTM_RS14935	COG0194	GDP metabolic process
SFSGTM_RS14950	COG1561	YicC-like family, N-terminal region
SFSGTM_RS14955	COG0515	serine threonine protein kinase
SFSGTM_RS14955	COG3266	domain, Protein
SFSGTM_RS14960	COG0631	protein serine/threonine phosphatase activity
SFSGTM_RS14965	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SFSGTM_RS14970	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SFSGTM_RS14975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SFSGTM_RS14980	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SFSGTM_RS15010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SFSGTM_RS15020	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SFSGTM_RS15025	COG0316	Belongs to the HesB IscA family
SFSGTM_RS15030	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SFSGTM_RS15035	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SFSGTM_RS15045	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SFSGTM_RS15050	COG1765	OsmC-like protein
SFSGTM_RS15060	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
SFSGTM_RS15065	COG2027	D-alanyl-D-alanine carboxypeptidase
SFSGTM_RS15075	COG2885	chlorophyll binding
SFSGTM_RS15080	COG1272	protein, Hemolysin III
SFSGTM_RS15085	COG3134	Outer membrane lipoprotein
SFSGTM_RS15110	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SFSGTM_RS15110	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SFSGTM_RS15115	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SFSGTM_RS15135	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS15140	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS15150	COG1970	mechanosensitive ion channel activity
SFSGTM_RS15155	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
SFSGTM_RS15160	COG4191	Histidine kinase
SFSGTM_RS15190	COG1660	Displays ATPase and GTPase activities
SFSGTM_RS15195	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SFSGTM_RS15205	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SFSGTM_RS15215	COG1137	ATPase activity
SFSGTM_RS15230	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SFSGTM_RS15245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SFSGTM_RS15250	COG0543	2 iron, 2 sulfur cluster binding
SFSGTM_RS15250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SFSGTM_RS15260	COG3077	Addiction module antitoxin, RelB DinJ family
SFSGTM_RS15265	COG3041	Addiction module toxin RelE StbE family
SFSGTM_RS15280	COG3501	Rhs element vgr protein
SFSGTM_RS15370	COG4372	Transposase
SFSGTM_RS15380	COG1794	racemase activity, acting on amino acids and derivatives
SFSGTM_RS15410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SFSGTM_RS15430	COG1192	Involved in chromosome partitioning
SFSGTM_RS15450	COG2837	iron assimilation
SFSGTM_RS15480	COG4941	Belongs to the sigma-70 factor family
SFSGTM_RS15495	COG3795	YCII-related domain
SFSGTM_RS15515	COG4372	Transposase
SFSGTM_RS15550	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SFSGTM_RS15570	COG3002	Belongs to the UPF0753 family
SFSGTM_RS15575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SFSGTM_RS15595	COG1192	Involved in chromosome partitioning
SFSGTM_RS15650	COG1850	ribulose-bisphosphate carboxylase activity
SFSGTM_RS15655	COG0058	SHG alpha-glucan phosphorylase activity
SFSGTM_RS15680	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SFSGTM_RS15690	COG2217	Heavy metal translocating P-type atpase
SFSGTM_RS15695	COG2326	polyphosphate kinase activity
SFSGTM_RS15700	COG2888	peptidyl-tyrosine sulfation
SFSGTM_RS15730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SFSGTM_RS15805	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SFSGTM_RS15810	COG0671	phosphoesterase, PA-phosphatase related
SFSGTM_RS15820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SFSGTM_RS15825	COG4115	mRNA cleavage
SFSGTM_RS15830	COG2161	toxin-antitoxin pair type II binding
SFSGTM_RS15845	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS15850	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS15875	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS15880	COG4974	Belongs to the 'phage' integrase family
SFSGTM_RS15900	COG1028	Short-chain dehydrogenase reductase Sdr
SFSGTM_RS15930	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SFSGTM_RS15940	COG0557	exoribonuclease II activity
SFSGTM_RS15945	COG3150	esterase
SFSGTM_RS15950	COG1686	Belongs to the peptidase S11 family
SFSGTM_RS15960	COG1187	pseudouridine synthase activity
SFSGTM_RS15970	COG1595	DNA-templated transcription, initiation
SFSGTM_RS15985	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SFSGTM_RS15990	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SFSGTM_RS15995	COG0840	transmembrane signaling receptor activity
SFSGTM_RS16010	COG1131	(ABC) transporter
SFSGTM_RS16015	COG0842	Transport permease protein
SFSGTM_RS16035	COG1067	ATP-dependent peptidase activity
SFSGTM_RS16040	COG0070	glutamate synthase
SFSGTM_RS16040	COG0069	glutamate synthase activity
SFSGTM_RS16040	COG0067	glutamate synthase
SFSGTM_RS16045	COG0493	'glutamate synthase
SFSGTM_RS16050	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SFSGTM_RS16055	COG1028	Short-chain dehydrogenase reductase Sdr
SFSGTM_RS16100	COG0475	glutathione-regulated potassium exporter activity
SFSGTM_RS16135	COG0318	PFAM AMP-dependent synthetase and ligase
SFSGTM_RS16150	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SFSGTM_RS16155	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SFSGTM_RS16160	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SFSGTM_RS16175	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SFSGTM_RS16180	COG0488	(ABC) transporter
SFSGTM_RS16195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SFSGTM_RS16195	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SFSGTM_RS16200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SFSGTM_RS16215	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SFSGTM_RS16220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SFSGTM_RS16225	COG0126	phosphoglycerate kinase activity
SFSGTM_RS16230	COG0469	pyruvate kinase activity
SFSGTM_RS16240	COG4535	Mg2 and Co2 transporter CorC
SFSGTM_RS16245	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SFSGTM_RS16250	COG1702	phosphate starvation-inducible protein PhoH
SFSGTM_RS16255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SFSGTM_RS16265	COG4771	TonB-dependent receptor
SFSGTM_RS16270	COG0628	permease
SFSGTM_RS16280	COG0084	hydrolase, TatD family'
SFSGTM_RS16320	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SFSGTM_RS16325	COG3657	addiction module killer protein
SFSGTM_RS16345	COG2329	Antibiotic biosynthesis monooxygenase
SFSGTM_RS16360	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SFSGTM_RS16410	COG0288	reversible hydration of carbon dioxide
SFSGTM_RS16425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SFSGTM_RS16435	COG1649	PFAM Uncharacterised BCR, COG1649
SFSGTM_RS16435	COG0726	polysaccharide deacetylase
SFSGTM_RS16440	COG1215	transferase activity, transferring glycosyl groups
SFSGTM_RS16455	COG4232	protein-disulfide reductase activity
SFSGTM_RS16460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SFSGTM_RS16465	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SFSGTM_RS16470	COG0511	ligase activity, forming carbon-carbon bonds
SFSGTM_RS16475	COG0439	Biotin carboxylase
SFSGTM_RS16480	COG2264	protein methyltransferase activity
SFSGTM_RS16490	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SFSGTM_RS16495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SFSGTM_RS16500	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SFSGTM_RS16505	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SFSGTM_RS16510	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SFSGTM_RS16515	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SFSGTM_RS16525	COG0356	it plays a direct role in the translocation of protons across the membrane
SFSGTM_RS16535	COG1475	DNA binding
SFSGTM_RS16540	COG1192	Involved in chromosome partitioning
SFSGTM_RS16545	COG0357	Ribosomal RNA small subunit methyltransferase G
SFSGTM_RS16550	COG0445	tRNA wobble uridine modification
SFSGTM_RS16555	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SFSGTM_RS16560	COG0706	membrane insertase activity
SFSGTM_RS16565	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SFSGTM_RS16575	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SFSGTM_RS16580	COG1192	Involved in chromosome partitioning
SFSGTM_RS16610	COG2197	response regulator
SFSGTM_RS16620	COG3916	Acyl-homoserine-lactone synthase
SFSGTM_RS16635	COG0384	phenazine biosynthesis protein PhzF
SFSGTM_RS16660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SFSGTM_RS16685	COG2226	methyltransferase
SFSGTM_RS16735	COG3501	Rhs element vgr protein
SFSGTM_RS16755	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SFSGTM_RS16760	COG3657	addiction module killer protein
SFSGTM_RS16790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SFSGTM_RS16810	COG0484	heat shock protein binding
SFSGTM_RS16820	COG2944	sequence-specific DNA binding
SFSGTM_RS16835	COG4453	Protein conserved in bacteria
SFSGTM_RS16850	COG3328	transposase activity
SFSGTM_RS16855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SFSGTM_RS16875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SFSGTM_RS16895	COG1192	Involved in chromosome partitioning
SFSGTM_RS16915	COG3668	Plasmid stabilization system
SFSGTM_RS16930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs