locus-tag	class	description
EL386_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EL386_RS00020	COG0187	DNA topoisomerase II activity
EL386_RS00030	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EL386_RS00040	COG0751	glycine-tRNA ligase activity
EL386_RS00045	COG0752	glycyl-tRNA synthetase alpha subunit
EL386_RS00050	COG0482	sulfurtransferase activity
EL386_RS00055	COG0425	Belongs to the sulfur carrier protein TusA family
EL386_RS00060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EL386_RS00065	COG0174	glutamine synthetase
EL386_RS00075	COG3852	Histidine kinase
EL386_RS00110	COG2165	general secretion pathway protein
EL386_RS00120	COG2165	general secretion pathway protein
EL386_RS00130	COG1459	type II secretion system
EL386_RS00135	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EL386_RS00140	COG0167	dihydroorotate dehydrogenase activity
EL386_RS00145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EL386_RS00165	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EL386_RS00170	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EL386_RS00175	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EL386_RS00180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EL386_RS00190	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EL386_RS00195	COG4942	peptidase
EL386_RS00200	COG0793	Belongs to the peptidase S41A family
EL386_RS00205	COG2861	carbohydrate metabolic process
EL386_RS00210	COG0693	protein deglycase activity
EL386_RS00215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EL386_RS00225	COG2226	methyltransferase
EL386_RS00235	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EL386_RS00240	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EL386_RS00255	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EL386_RS00270	COG4191	Histidine kinase
EL386_RS00275	COG2204	response regulator
EL386_RS00305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EL386_RS00320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EL386_RS00320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EL386_RS00340	COG1333	cytochrome c biogenesis protein
EL386_RS00345	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EL386_RS00385	COG2010	Cytochrome c
EL386_RS00395	COG0714	Associated with various cellular activities
EL386_RS00415	COG0348	domain, Protein
EL386_RS00415	COG3901	Regulator of nitric oxide reductase transcription
EL386_RS00425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EL386_RS00425	COG1648	precorrin-2 dehydrogenase activity
EL386_RS00460	COG0535	radical SAM domain protein
EL386_RS00485	COG0606	chelatase, subunit chli
EL386_RS00490	COG2960	long-chain fatty acid transporting porin activity
EL386_RS00500	COG0347	Belongs to the P(II) protein family
EL386_RS00505	COG0004	ammonium transporteR
EL386_RS00515	COG4619	ABC transporter
EL386_RS00520	COG0390	transport system, permease component
EL386_RS00535	COG2084	Dehydrogenase
EL386_RS00540	COG0840	transmembrane signaling receptor activity
EL386_RS00550	COG0018	arginyl-trna synthetase
EL386_RS00555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EL386_RS00560	COG1639	'signal transduction protein
EL386_RS00565	COG0784	Response regulator, receiver
EL386_RS00565	COG2205	protein histidine kinase activity
EL386_RS00575	COG3001	Fructosamine kinase
EL386_RS00590	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EL386_RS00595	COG0493	'glutamate synthase
EL386_RS00600	COG0069	glutamate synthase activity
EL386_RS00600	COG0070	glutamate synthase
EL386_RS00600	COG0067	glutamate synthase
EL386_RS00615	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EL386_RS00620	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EL386_RS00625	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EL386_RS00670	COG0281	malic enzyme
EL386_RS00680	COG1525	nuclease
EL386_RS00685	COG0254	rRNA binding
EL386_RS00695	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EL386_RS00730	COG2165	general secretion pathway protein
EL386_RS00740	COG2165	general secretion pathway protein
EL386_RS00765	COG0784	Response regulator, receiver
EL386_RS00765	COG2198	Histidine kinase
EL386_RS00765	COG2205	protein histidine kinase activity
EL386_RS00770	COG1011	Hydrolase
EL386_RS00780	COG0494	nUDIX hydrolase
EL386_RS00805	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EL386_RS00830	COG3706	GGDEF domain
EL386_RS00835	COG1022	Amp-dependent synthetase and ligase
EL386_RS00845	COG2022	thiamine diphosphate biosynthetic process
EL386_RS00850	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EL386_RS00905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EL386_RS00915	COG3954	Phosphoribulokinase
EL386_RS00930	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EL386_RS00935	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EL386_RS00940	COG0631	protein serine/threonine phosphatase activity
EL386_RS00950	COG1561	YicC-like family, N-terminal region
EL386_RS00955	COG0194	GDP metabolic process
EL386_RS00960	COG1758	RNA polymerase activity
EL386_RS00965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EL386_RS00975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EL386_RS00980	COG3161	chorismate lyase activity
EL386_RS00985	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EL386_RS01010	COG1450	Type ii and iii secretion system protein
EL386_RS01015	COG3409	Peptidoglycan-binding domain 1 protein
EL386_RS01015	COG3267	Type II secretory pathway component ExeA
EL386_RS01030	COG1040	competence protein
EL386_RS01035	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EL386_RS01040	COG0156	8-amino-7-oxononanoate synthase activity
EL386_RS01045	COG0596	Alpha beta hydrolase
EL386_RS01050	COG2226	methyltransferase
EL386_RS01055	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EL386_RS01065	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EL386_RS01070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EL386_RS01100	COG0109	protoheme IX farnesyltransferase activity
EL386_RS01115	COG2177	Part of the ABC transporter FtsEX involved in
EL386_RS01120	COG2884	Cell division ATP-binding protein ftsE
EL386_RS01125	COG0552	protein localization to endoplasmic reticulum
EL386_RS01130	COG0612	Peptidase, M16
EL386_RS01135	COG0612	Peptidase, M16
EL386_RS01140	COG0714	Associated with various cellular activities
EL386_RS01180	COG2801	Transposase and inactivated derivatives
EL386_RS01215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EL386_RS01220	COG1704	LemA family
EL386_RS01225	COG0501	Belongs to the peptidase M48B family
EL386_RS01230	COG0625	glutathione transferase activity
EL386_RS01235	COG1733	regulation of RNA biosynthetic process
EL386_RS01255	COG2824	Alkylphosphonate utilization operon protein PhnA
EL386_RS01265	COG0742	ribosomal rna small subunit methyltransferase
EL386_RS01270	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EL386_RS01275	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EL386_RS01280	COG0405	Gamma-glutamyltransferase
EL386_RS01290	COG3706	GGDEF domain
EL386_RS01295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EL386_RS01315	COG1131	(ABC) transporter
EL386_RS01320	COG3706	GGDEF domain
EL386_RS01330	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EL386_RS01345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EL386_RS01350	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EL386_RS01355	COG2003	Belongs to the UPF0758 family
EL386_RS01360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EL386_RS01365	COG0756	dUTP diphosphatase activity
EL386_RS01375	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EL386_RS01395	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EL386_RS01400	COG0708	Exodeoxyribonuclease III
EL386_RS01430	COG2211	Major facilitator Superfamily
EL386_RS01445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EL386_RS01450	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EL386_RS01455	COG1872	DUF167
EL386_RS01490	COG2210	Belongs to the sulfur carrier protein TusA family
EL386_RS01525	COG0543	2 iron, 2 sulfur cluster binding
EL386_RS01535	COG0540	Belongs to the ATCase OTCase family
EL386_RS01540	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EL386_RS01545	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EL386_RS01550	COG1678	Uncharacterized ACR, COG1678
EL386_RS01575	COG0189	ligase activity
EL386_RS01595	COG0840	transmembrane signaling receptor activity
EL386_RS01605	COG2198	Histidine kinase
EL386_RS01605	COG0784	Response regulator, receiver
EL386_RS01605	COG0643	Histidine kinase
EL386_RS01610	COG2201	protein-glutamate methylesterase activity
EL386_RS01620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EL386_RS01625	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EL386_RS01630	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EL386_RS01635	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EL386_RS01645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EL386_RS01650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EL386_RS01655	COG0126	phosphoglycerate kinase activity
EL386_RS01660	COG0469	pyruvate kinase activity
EL386_RS01675	COG3647	Membrane
EL386_RS01680	COG5002	protein histidine kinase activity
EL386_RS01680	COG5000	phosphorelay sensor kinase activity
EL386_RS01690	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EL386_RS01705	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EL386_RS01710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EL386_RS01715	COG0242	peptide deformylase activity
EL386_RS01735	COG0564	pseudouridine synthase activity
EL386_RS01740	COG2813	Specifically methylates the guanine in position
EL386_RS01745	COG0406	alpha-ribazole phosphatase activity
EL386_RS01780	COG1850	ribulose-bisphosphate carboxylase activity
EL386_RS01800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL386_RS01805	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EL386_RS01810	COG3258	Cytochrome c
EL386_RS01865	COG2217	Heavy metal translocating P-type atpase
EL386_RS01870	COG2217	Heavy metal translocating P-type atpase
EL386_RS01885	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EL386_RS01905	COG0546	phosphoglycolate phosphatase activity
EL386_RS01910	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EL386_RS01920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EL386_RS01925	COG0134	indole-3-glycerol-phosphate synthase activity
EL386_RS01930	COG0457	Tetratricopeptide repeat
EL386_RS01940	COG1765	OsmC-like protein
EL386_RS01950	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EL386_RS01955	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EL386_RS01960	COG0247	lactate metabolic process
EL386_RS01970	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EL386_RS01975	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EL386_RS01990	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EL386_RS01995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EL386_RS02010	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EL386_RS02035	COG0006	proline dipeptidase activity
EL386_RS02040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EL386_RS02045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EL386_RS02060	COG1178	ABC-type Fe3 transport system permease component
EL386_RS02065	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EL386_RS02075	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EL386_RS02080	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EL386_RS02090	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EL386_RS02100	COG2226	methyltransferase
EL386_RS02130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EL386_RS02135	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EL386_RS02140	COG0674	pyruvate-flavodoxin oxidoreductase activity
EL386_RS02150	COG0318	PFAM AMP-dependent synthetase and ligase
EL386_RS02155	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EL386_RS02165	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EL386_RS02170	COG3118	belongs to the thioredoxin family
EL386_RS02175	COG0745	RESPONSE REGULATOR receiver
EL386_RS02180	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EL386_RS02190	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EL386_RS02210	COG3083	sulfuric ester hydrolase activity
EL386_RS02215	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EL386_RS02220	COG2967	ApaG domain
EL386_RS02230	COG0673	inositol 2-dehydrogenase activity
EL386_RS02250	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EL386_RS02260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EL386_RS02265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EL386_RS02280	COG3178	'Phosphotransferase
EL386_RS02345	COG0583	DNA-binding transcription factor activity
EL386_RS02350	COG3122	Protein conserved in bacteria
EL386_RS02355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EL386_RS02405	COG0346	lactoylglutathione lyase activity
EL386_RS02455	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EL386_RS02460	COG0321	lipoyl(octanoyl) transferase activity
EL386_RS02465	COG2921	Belongs to the UPF0250 family
EL386_RS02510	COG0574	Belongs to the PEP-utilizing enzyme family
EL386_RS02510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EL386_RS02545	COG2226	methyltransferase
EL386_RS02560	COG0670	Belongs to the BI1 family
EL386_RS02570	COG0583	DNA-binding transcription factor activity
EL386_RS02575	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EL386_RS02585	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EL386_RS02600	COG1850	ribulose-bisphosphate carboxylase activity
EL386_RS02605	COG4451	ribulose bisphosphate carboxylase, small
EL386_RS02630	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EL386_RS02635	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EL386_RS02640	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EL386_RS02645	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EL386_RS02675	COG0583	DNA-binding transcription factor activity
EL386_RS02680	COG0659	secondary active sulfate transmembrane transporter activity
EL386_RS02700	COG2951	lytic endotransglycosylase activity
EL386_RS02705	COG0772	Belongs to the SEDS family
EL386_RS02710	COG0768	penicillin binding
EL386_RS02715	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EL386_RS02720	COG1792	Involved in formation and maintenance of cell shape
EL386_RS02725	COG1077	Cell shape determining protein MreB Mrl
EL386_RS02730	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EL386_RS02735	COG0154	amidase activity
EL386_RS02740	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EL386_RS02745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EL386_RS02755	COG2890	protein-(glutamine-N5) methyltransferase activity
EL386_RS02760	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EL386_RS02765	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EL386_RS02775	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EL386_RS02780	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EL386_RS02790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EL386_RS02795	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EL386_RS02800	COG0193	aminoacyl-tRNA hydrolase activity
EL386_RS02805	COG0012	GTP binding
EL386_RS02820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EL386_RS02835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EL386_RS02840	COG0116	Belongs to the methyltransferase superfamily
EL386_RS02840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EL386_RS02845	COG1131	(ABC) transporter
EL386_RS02850	COG0842	Transport permease protein
EL386_RS02875	COG2827	Endonuclease containing a URI domain
EL386_RS02885	COG3012	SEC-C Motif Domain Protein
EL386_RS02890	COG0004	ammonium transporteR
EL386_RS02900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EL386_RS02905	COG1702	phosphate starvation-inducible protein PhoH
EL386_RS02915	COG4535	Mg2 and Co2 transporter CorC
EL386_RS02920	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EL386_RS02940	COG2818	Glycosylase
EL386_RS02950	COG4807	Protein conserved in bacteria
EL386_RS02970	COG0625	glutathione transferase activity
EL386_RS02995	COG2084	Dehydrogenase
EL386_RS03000	COG0583	DNA-binding transcription factor activity
EL386_RS03005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EL386_RS03030	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EL386_RS03030	COG3608	succinylglutamate desuccinylase aspartoacylase
EL386_RS03070	COG0495	leucyl-tRNA aminoacylation
EL386_RS03075	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EL386_RS03085	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EL386_RS03090	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EL386_RS03100	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EL386_RS03105	COG0424	maF-like protein
EL386_RS03110	COG1530	ribonuclease E activity
EL386_RS03125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EL386_RS03130	COG0312	modulator of DNA gyrase
EL386_RS03145	COG3028	Belongs to the UPF0307 family
EL386_RS03150	COG0312	modulator of DNA gyrase
EL386_RS03160	COG0730	response to heat
EL386_RS03165	COG2814	Major facilitator Superfamily
EL386_RS03195	COG0789	Transcriptional regulator
EL386_RS03220	COG0475	glutathione-regulated potassium exporter activity
EL386_RS03225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EL386_RS03230	COG0583	DNA-binding transcription factor activity
EL386_RS03240	COG0288	reversible hydration of carbon dioxide
EL386_RS03255	COG1309	transcriptional regulator
EL386_RS03275	COG2239	Acts as a magnesium transporter
EL386_RS03280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EL386_RS03285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL386_RS03295	COG1660	Displays ATPase and GTPase activities
EL386_RS03300	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EL386_RS03320	COG1137	ATPase activity
EL386_RS03335	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EL386_RS03350	COG2853	Lipoprotein
EL386_RS03365	COG1127	ABC transporter
EL386_RS03370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EL386_RS03375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EL386_RS03385	COG5007	Belongs to the BolA IbaG family
EL386_RS03390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EL386_RS03395	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EL386_RS03400	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EL386_RS03405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EL386_RS03470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EL386_RS03475	COG0723	plastoquinol--plastocyanin reductase activity
EL386_RS03480	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EL386_RS03485	COG2857	Cytochrome c1
EL386_RS03490	COG0625	glutathione transferase activity
EL386_RS03495	COG2969	positive regulation of protein catabolic process
EL386_RS03505	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EL386_RS03510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EL386_RS03515	COG0277	FAD linked oxidase domain protein
EL386_RS03520	COG2823	Periplasmic or secreted lipoprotein
EL386_RS03525	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EL386_RS03530	COG0792	nuclease activity
EL386_RS03550	COG2001	Belongs to the MraZ family
EL386_RS03555	COG0275	rRNA processing
EL386_RS03560	COG3116	cell division
EL386_RS03570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EL386_RS03575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EL386_RS03580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EL386_RS03585	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EL386_RS03590	COG0772	Belongs to the SEDS family
EL386_RS03595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EL386_RS03600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EL386_RS03605	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EL386_RS03610	COG1181	Belongs to the D-alanine--D-alanine ligase family
EL386_RS03615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EL386_RS03630	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EL386_RS03640	COG0739	heme binding
EL386_RS03645	COG0653	protein targeting
EL386_RS03650	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EL386_RS03655	COG0352	thiamine-phosphate diphosphorylase activity
EL386_RS03665	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EL386_RS03675	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EL386_RS03720	COG0045	succinate-CoA ligase (ADP-forming) activity
EL386_RS03725	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EL386_RS03730	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EL386_RS03730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EL386_RS03750	COG1496	oxidoreductase activity
EL386_RS03765	COG2226	methyltransferase
EL386_RS03775	COG3830	Belongs to the UPF0237 family
EL386_RS03780	COG0242	peptide deformylase activity
EL386_RS03785	COG0204	Acyl-transferase
EL386_RS03790	COG0542	response to heat
EL386_RS03820	COG1295	ribonuclease BN
EL386_RS03835	COG0300	oxidoreductase activity
EL386_RS03845	COG5265	(ABC) transporter
EL386_RS03860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EL386_RS03880	COG0501	Belongs to the peptidase M48B family
EL386_RS03890	COG3228	Belongs to the MtfA family
EL386_RS03910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL386_RS03915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EL386_RS03920	COG1278	Cold shock
EL386_RS03935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL386_RS03940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EL386_RS03945	COG4206	TonB-dependent receptor
EL386_RS03960	COG0778	Nitroreductase
EL386_RS03965	COG1492	cobalamin metabolic process
EL386_RS03980	COG0406	alpha-ribazole phosphatase activity
EL386_RS03985	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EL386_RS03990	COG0671	phosphoesterase, PA-phosphatase related
EL386_RS04010	COG0494	nUDIX hydrolase
EL386_RS04015	COG0217	transcriptional regulatory protein
EL386_RS04020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EL386_RS04025	COG0632	four-way junction helicase activity
EL386_RS04030	COG2255	four-way junction helicase activity
EL386_RS04035	COG0824	Thioesterase
EL386_RS04055	COG0823	Involved in the tonB-independent uptake of proteins
EL386_RS04070	COG0602	queuosine metabolic process
EL386_RS04075	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EL386_RS04110	COG0583	DNA-binding transcription factor activity
EL386_RS04125	COG0737	Belongs to the 5'-nucleotidase family
EL386_RS04130	COG3258	Cytochrome c
EL386_RS04150	COG4783	chaperone-mediated protein folding
EL386_RS04155	COG0425	Belongs to the sulfur carrier protein TusA family
EL386_RS04160	COG2210	Belongs to the sulfur carrier protein TusA family
EL386_RS04165	COG2067	long-chain fatty acid transport protein
EL386_RS04205	COG0784	Response regulator, receiver
EL386_RS04205	COG0835	chemotaxis
EL386_RS04210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EL386_RS04220	COG1558	bacterial-type flagellum-dependent cell motility
EL386_RS04225	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EL386_RS04230	COG1749	Flagellar hook protein flgE
EL386_RS04245	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EL386_RS04250	COG1706	bacterial-type flagellum-dependent cell motility
EL386_RS04255	COG3951	Flagellar rod assembly protein muramidase FlgJ
EL386_RS04255	COG1705	Flagellar rod assembly protein muramidase FlgJ
EL386_RS04285	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EL386_RS04320	COG1677	Flagellar hook-basal body complex protein FliE
EL386_RS04330	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EL386_RS04380	COG1987	bacterial-type flagellum assembly
EL386_RS04395	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EL386_RS04425	COG2198	Histidine kinase
EL386_RS04425	COG0643	Histidine kinase
EL386_RS04425	COG0784	Response regulator, receiver
EL386_RS04435	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EL386_RS04440	COG1360	Flagellar Motor Protein
EL386_RS04445	COG1192	Involved in chromosome partitioning
EL386_RS04455	COG0835	chemotaxis
EL386_RS04465	COG5002	protein histidine kinase activity
EL386_RS04465	COG5001	Diguanylate cyclase
EL386_RS04490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EL386_RS04495	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EL386_RS04500	COG0022	dehydrogenase e1 component
EL386_RS04500	COG0508	dehydrogenase complex catalyzes the overall conversion of
EL386_RS04515	COG0137	argininosuccinate synthase activity
EL386_RS04520	COG5001	Diguanylate cyclase
EL386_RS04520	COG5002	protein histidine kinase activity
EL386_RS04535	COG3220	belongs to the UPF0276 family
EL386_RS04555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EL386_RS04560	COG4660	Part of a membrane complex involved in electron transport
EL386_RS04565	COG4659	FMN binding
EL386_RS04580	COG2878	Part of a membrane complex involved in electron transport
EL386_RS04585	COG4657	Part of a membrane complex involved in electron transport
EL386_RS04590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL386_RS04590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL386_RS04595	COG0489	protein tyrosine kinase activity
EL386_RS04600	COG0717	Belongs to the dCTP deaminase family
EL386_RS04610	COG3795	YCII-related domain
EL386_RS04675	COG0745	RESPONSE REGULATOR receiver
EL386_RS04695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EL386_RS04700	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EL386_RS04710	COG0628	permease
EL386_RS04730	COG1393	Belongs to the ArsC family
EL386_RS04740	COG1027	Aspartate ammonia-lyase
EL386_RS04745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL386_RS04765	COG1254	Belongs to the acylphosphatase family
EL386_RS04775	COG0442	prolyl-tRNA aminoacylation
EL386_RS04800	COG0517	IMP dehydrogenase activity
EL386_RS04800	COG1994	Peptidase M50
EL386_RS04810	COG1309	transcriptional regulator
EL386_RS04820	COG1902	pentaerythritol trinitrate reductase activity
EL386_RS04835	COG0028	Belongs to the TPP enzyme family
EL386_RS04840	COG0440	acetolactate synthase activity
EL386_RS04845	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EL386_RS04850	COG0688	phosphatidylethanolamine metabolic process
EL386_RS04855	COG1183	phosphatidylcholine synthase activity
EL386_RS04860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EL386_RS04865	COG1573	uracil-dna glycosylase
EL386_RS04875	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EL386_RS04900	COG0348	domain, Protein
EL386_RS04910	COG2010	Cytochrome c
EL386_RS04925	COG3278	Belongs to the heme-copper respiratory oxidase family
EL386_RS04935	COG2217	Heavy metal translocating P-type atpase
EL386_RS04945	COG1024	Enoyl-CoA hydratase
EL386_RS04950	COG2205	protein histidine kinase activity
EL386_RS04950	COG2198	Histidine kinase
EL386_RS04950	COG0784	Response regulator, receiver
EL386_RS04960	COG0525	valine-tRNA ligase activity
EL386_RS04975	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EL386_RS04980	COG0795	lipopolysaccharide-transporting ATPase activity
EL386_RS04985	COG0795	lipopolysaccharide-transporting ATPase activity
EL386_RS04995	COG0617	tRNA 3'-terminal CCA addition
EL386_RS05000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EL386_RS05010	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EL386_RS05015	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EL386_RS05020	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EL386_RS05040	COG0398	Pfam SNARE associated Golgi protein
EL386_RS05050	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EL386_RS05055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EL386_RS05060	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EL386_RS05065	COG0412	Dienelactone hydrolase
EL386_RS05070	COG0513	Belongs to the DEAD box helicase family
EL386_RS05080	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EL386_RS05085	COG0343	queuine tRNA-ribosyltransferase activity
EL386_RS05090	COG1862	Preprotein translocase
EL386_RS05095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EL386_RS05100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EL386_RS05125	COG1959	2 iron, 2 sulfur cluster binding
EL386_RS05135	COG0822	iron-sulfur transferase activity
EL386_RS05140	COG0316	Belongs to the HesB IscA family
EL386_RS05145	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EL386_RS05150	COG0443	Heat shock 70 kDa protein
EL386_RS05160	COG2975	iron-sulfur cluster assembly
EL386_RS05165	COG0105	UTP biosynthetic process
EL386_RS05170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EL386_RS05180	COG1426	Protein conserved in bacteria
EL386_RS05185	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EL386_RS05190	COG0124	histidyl-tRNA synthetase
EL386_RS05195	COG2976	Protein conserved in bacteria
EL386_RS05205	COG1160	GTP binding
EL386_RS05235	COG1570	exodeoxyribonuclease VII activity
EL386_RS05250	COG0519	Catalyzes the synthesis of GMP from XMP
EL386_RS05250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EL386_RS05265	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EL386_RS05285	COG0583	DNA-binding transcription factor activity
EL386_RS05330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EL386_RS05335	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EL386_RS05340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EL386_RS05345	COG1162	GTPase activity
EL386_RS05350	COG2154	pterin-4-alpha-carbinolamine dehydratase
EL386_RS05355	COG0501	Belongs to the peptidase M48B family
EL386_RS05360	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EL386_RS05435	COG0714	Associated with various cellular activities
EL386_RS05445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EL386_RS05450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EL386_RS05470	COG0791	NLP P60 protein
EL386_RS05475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EL386_RS05490	COG1199	ATP-dependent helicase activity
EL386_RS05495	COG1214	PFAM Peptidase M22, glycoprotease
EL386_RS05540	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EL386_RS05555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EL386_RS05560	COG1393	Belongs to the ArsC family
EL386_RS05565	COG2171	N-acyltransferase activity
EL386_RS05570	COG0436	Aminotransferase
EL386_RS05605	COG0840	transmembrane signaling receptor activity
EL386_RS05610	COG2201	protein-glutamate methylesterase activity
EL386_RS05615	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EL386_RS05620	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EL386_RS05625	COG0840	transmembrane signaling receptor activity
EL386_RS05630	COG1192	Involved in chromosome partitioning
EL386_RS05635	COG0835	chemotaxis
EL386_RS05640	COG2198	Histidine kinase
EL386_RS05640	COG0643	Histidine kinase
EL386_RS05645	COG0745	RESPONSE REGULATOR receiver
EL386_RS05670	COG0247	lactate metabolic process
EL386_RS05675	COG0277	FAD linked oxidase domain protein
EL386_RS05685	COG0277	FAD linked oxidase domain protein
EL386_RS05695	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EL386_RS05705	COG0326	Molecular chaperone. Has ATPase activity
EL386_RS05715	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EL386_RS05725	COG3864	Putative metallopeptidase domain
EL386_RS05750	COG1595	DNA-templated transcription, initiation
EL386_RS05760	COG0563	adenylate kinase activity
EL386_RS05765	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EL386_RS05770	COG3954	Phosphoribulokinase
EL386_RS05790	COG2897	thiosulfate sulfurtransferase activity
EL386_RS05845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EL386_RS05855	COG0537	adenosine 5'-monophosphoramidase activity
EL386_RS05870	COG0784	Response regulator, receiver
EL386_RS05880	COG2197	response regulator
EL386_RS05890	COG0784	Response regulator, receiver
EL386_RS05890	COG2205	protein histidine kinase activity
EL386_RS05890	COG5002	protein histidine kinase activity
EL386_RS05895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EL386_RS05915	COG2205	protein histidine kinase activity
EL386_RS05965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EL386_RS05980	COG0191	fructose-bisphosphate aldolase activity
EL386_RS06000	COG0688	phosphatidylethanolamine metabolic process
EL386_RS06050	COG1643	Atp-dependent helicase
EL386_RS06070	COG1611	Belongs to the LOG family
EL386_RS06075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EL386_RS06100	COG2176	DNA-directed DNA polymerase activity
EL386_RS06115	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EL386_RS06120	COG4572	Cation transport regulator
EL386_RS06135	COG1408	metallophosphoesterase
EL386_RS06165	COG0398	Pfam SNARE associated Golgi protein
EL386_RS06190	COG0513	Belongs to the DEAD box helicase family
EL386_RS06195	COG1994	Peptidase M50
EL386_RS06200	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EL386_RS06220	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EL386_RS06230	COG4628	conserved protein (DUF2132)
EL386_RS06240	COG0676	glucose-6-phosphate 1-epimerase activity
EL386_RS06265	COG1234	tRNA 3'-trailer cleavage
EL386_RS06280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EL386_RS06285	COG1858	cytochrome C peroxidase
EL386_RS06290	COG1331	Highly conserved protein containing a thioredoxin domain
EL386_RS06325	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EL386_RS06330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EL386_RS06335	COG0363	glucosamine-6-phosphate deaminase activity
EL386_RS06345	COG0297	glycogen (starch) synthase activity
EL386_RS06350	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EL386_RS06355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EL386_RS06370	COG0058	SHG alpha-glucan phosphorylase activity
EL386_RS06375	COG0033	Phosphoglucomutase
EL386_RS06380	COG0166	Belongs to the GPI family
EL386_RS06385	COG0837	glucose binding
EL386_RS06390	COG4206	TonB-dependent receptor
EL386_RS06400	COG0811	peptide transport
EL386_RS06405	COG0848	biopolymer transport protein
EL386_RS06425	COG2132	Multicopper oxidase
EL386_RS06450	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EL386_RS06455	COG0733	neurotransmitter:sodium symporter activity
EL386_RS06460	COG2867	negative regulation of translational initiation
EL386_RS06465	COG2914	Belongs to the UPF0125 (RnfH) family
EL386_RS06470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EL386_RS06475	COG0735	belongs to the Fur family
EL386_RS06480	COG0497	DNA recombination
EL386_RS06490	COG1420	regulation of RNA biosynthetic process
EL386_RS06495	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EL386_RS06500	COG0443	Heat shock 70 kDa protein
EL386_RS06505	COG0484	heat shock protein binding
EL386_RS06510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EL386_RS06515	COG0505	Belongs to the CarA family
EL386_RS06520	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EL386_RS06525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EL386_RS06550	COG0674	pyruvate-flavodoxin oxidoreductase activity
EL386_RS06550	COG1013	pyruvate-flavodoxin oxidoreductase activity
EL386_RS06550	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EL386_RS06550	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EL386_RS06560	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EL386_RS06565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EL386_RS06570	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EL386_RS06575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EL386_RS06580	COG0149	triose-phosphate isomerase activity
EL386_RS06595	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EL386_RS06600	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EL386_RS06605	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EL386_RS06610	COG0649	NAD binding
EL386_RS06625	COG1034	ATP synthesis coupled electron transport
EL386_RS06630	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EL386_RS06635	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EL386_RS06645	COG0713	ATP synthesis coupled electron transport
EL386_RS06660	COG1007	ATP synthesis coupled electron transport
EL386_RS06675	COG5002	protein histidine kinase activity
EL386_RS06695	COG0779	Required for maturation of 30S ribosomal subunits
EL386_RS06700	COG0195	Participates in both transcription termination and antitermination
EL386_RS06700	COG2251	uridine kinase activity
EL386_RS06705	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EL386_RS06710	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EL386_RS06715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EL386_RS06720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EL386_RS06725	COG1185	polyribonucleotide nucleotidyltransferase activity
EL386_RS06730	COG3266	domain, Protein
EL386_RS06740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EL386_RS06740	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EL386_RS06745	COG5002	protein histidine kinase activity
EL386_RS06755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EL386_RS06760	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EL386_RS06765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EL386_RS06770	COG0436	Aminotransferase
EL386_RS06785	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EL386_RS06790	COG1196	nuclear chromosome segregation
EL386_RS06795	COG3115	cell septum assembly
EL386_RS06815	COG0471	metal ion transport
EL386_RS06815	COG3273	potassium ion transport
EL386_RS06820	COG0659	secondary active sulfate transmembrane transporter activity
EL386_RS06825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EL386_RS06835	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EL386_RS06840	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EL386_RS06850	COG0330	HflC and HflK could
EL386_RS06885	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EL386_RS06890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EL386_RS06900	COG2350	Protein conserved in bacteria
EL386_RS06905	COG2917	probably involved in intracellular septation
EL386_RS06910	COG0613	PHP domain protein
EL386_RS06915	COG0009	L-threonylcarbamoyladenylate synthase
EL386_RS06920	COG0180	Tryptophanyl-tRNA synthetase
EL386_RS06930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EL386_RS06935	COG1187	pseudouridine synthase activity
EL386_RS06955	COG1028	Short-chain dehydrogenase reductase Sdr
EL386_RS06960	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EL386_RS06970	COG1562	ergosterol biosynthetic process
EL386_RS06980	COG1322	Protein conserved in bacteria
EL386_RS06985	COG0784	Response regulator, receiver
EL386_RS06985	COG2205	protein histidine kinase activity
EL386_RS06985	COG5002	protein histidine kinase activity
EL386_RS06995	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EL386_RS07015	COG1280	lysine exporter protein (LysE YggA)
EL386_RS07040	COG4335	DNA alkylation repair
EL386_RS07050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EL386_RS07060	COG0402	S-adenosylhomocysteine deaminase activity
EL386_RS07065	COG2954	triphosphatase activity
EL386_RS07080	COG0601	transmembrane transport
EL386_RS07085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EL386_RS07090	COG4133	protoheme IX ABC transporter activity
EL386_RS07105	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EL386_RS07110	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EL386_RS07120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL386_RS07135	COG0189	ligase activity
EL386_RS07135	COG4067	protein conserved in archaea
EL386_RS07140	COG0189	ligase activity
EL386_RS07150	COG0583	DNA-binding transcription factor activity
EL386_RS07160	COG1472	Belongs to the glycosyl hydrolase 3 family
EL386_RS07165	COG0668	transmembrane transport
EL386_RS07175	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EL386_RS07240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EL386_RS07245	COG1309	transcriptional regulator
EL386_RS07265	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EL386_RS07275	COG4591	ABC-type transport system involved in lipoprotein release permease component
EL386_RS07280	COG1136	(ABC) transporter
EL386_RS07290	COG2333	competence protein COMEC
EL386_RS07290	COG0658	competence protein
EL386_RS07295	COG0811	peptide transport
EL386_RS07300	COG0848	biopolymer transport protein
EL386_RS07305	COG1132	(ABC) transporter
EL386_RS07310	COG1663	tetraacyldisaccharide 4'-kinase activity
EL386_RS07315	COG1663	tetraacyldisaccharide 4'-kinase activity
EL386_RS07315	COG2835	tetraacyldisaccharide 4'-kinase activity
EL386_RS07320	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EL386_RS07335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EL386_RS07340	COG1530	ribonuclease E activity
EL386_RS07350	COG0546	phosphoglycolate phosphatase activity
EL386_RS07375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EL386_RS07380	COG0348	domain, Protein
EL386_RS07380	COG3901	Regulator of nitric oxide reductase transcription
EL386_RS07400	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EL386_RS07410	COG0424	maF-like protein
EL386_RS07415	COG0511	ligase activity, forming carbon-carbon bonds
EL386_RS07415	COG5016	pyruvate
EL386_RS07420	COG0439	Biotin carboxylase
EL386_RS07425	COG1399	metal-binding, possibly nucleic acid-binding protein
EL386_RS07430	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EL386_RS07435	COG0416	fatty acid biosynthetic process
EL386_RS07440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EL386_RS07445	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EL386_RS07455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EL386_RS07460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EL386_RS07465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EL386_RS07470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EL386_RS07475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EL386_RS07480	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EL386_RS07495	COG0084	hydrolase, TatD family'
EL386_RS07505	COG1022	Amp-dependent synthetase and ligase
EL386_RS07520	COG1960	acyl-CoA dehydrogenase activity
EL386_RS07530	COG1104	cysteine desulfurase activity
EL386_RS07545	COG0583	DNA-binding transcription factor activity
EL386_RS07565	COG0784	Response regulator, receiver
EL386_RS07565	COG2205	protein histidine kinase activity
EL386_RS07565	COG5002	protein histidine kinase activity
EL386_RS07585	COG0028	Belongs to the TPP enzyme family
EL386_RS07645	COG2205	protein histidine kinase activity
EL386_RS07655	COG0583	DNA-binding transcription factor activity
EL386_RS07660	COG2259	Doxx family
EL386_RS07665	COG0435	Glutathione S-transferase
EL386_RS07675	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EL386_RS07680	COG0564	pseudouridine synthase activity
EL386_RS07715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EL386_RS07725	COG0668	transmembrane transport
EL386_RS07740	COG2095	MarC family integral membrane protein
EL386_RS07745	COG3706	GGDEF domain
EL386_RS07770	COG1301	dicarboxylic acid transport
EL386_RS07775	COG1253	flavin adenine dinucleotide binding
EL386_RS07780	COG3431	PFAM Phosphate-starvation-inducible E
EL386_RS07790	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EL386_RS07795	COG1253	flavin adenine dinucleotide binding
EL386_RS07800	COG4536	flavin adenine dinucleotide binding
EL386_RS07805	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EL386_RS07810	COG0589	response to stress
EL386_RS07820	COG0318	PFAM AMP-dependent synthetase and ligase
EL386_RS07830	COG0058	SHG alpha-glucan phosphorylase activity
EL386_RS07845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EL386_RS07850	COG0561	phosphatase activity
EL386_RS07850	COG3100	YcgL domain-containing protein
EL386_RS07855	COG0438	transferase activity, transferring glycosyl groups
EL386_RS07860	COG2911	Protein conserved in bacteria
EL386_RS07865	COG0729	surface antigen
EL386_RS07875	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EL386_RS07885	COG0598	Magnesium transport protein CorA
EL386_RS07895	COG4067	protein conserved in archaea
EL386_RS07895	COG0189	ligase activity
EL386_RS07905	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EL386_RS07935	COG0513	Belongs to the DEAD box helicase family
EL386_RS07965	COG1858	cytochrome C peroxidase
EL386_RS07980	COG0298	carbon dioxide binding
EL386_RS07985	COG0375	protein maturation
EL386_RS08000	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EL386_RS08025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EL386_RS08030	COG0322	excinuclease ABC activity
EL386_RS08035	COG1573	uracil-dna glycosylase
EL386_RS08060	COG0670	Belongs to the BI1 family
EL386_RS08120	COG4067	protein conserved in archaea
EL386_RS08120	COG0189	ligase activity
EL386_RS08130	COG3128	pkhd-type hydroxylase
EL386_RS08135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EL386_RS08155	COG2920	part of a sulfur-relay system
EL386_RS08180	COG2221	Nitrite and sulphite reductase 4Fe-4S
EL386_RS08185	COG2221	Nitrite and sulphite reductase 4Fe-4S
EL386_RS08190	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EL386_RS08195	COG2923	Belongs to the DsrF TusC family
EL386_RS08205	COG2920	part of a sulfur-relay system
EL386_RS08240	COG1797	cobyrinic acid a,c-diamide synthase activity
EL386_RS08255	COG4585	Histidine kinase
EL386_RS08260	COG2197	response regulator
EL386_RS08265	COG1054	Belongs to the UPF0176 family
EL386_RS08275	COG1716	ATPase activity
EL386_RS08275	COG5001	Diguanylate cyclase
EL386_RS08280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EL386_RS08280	COG1648	precorrin-2 dehydrogenase activity
EL386_RS08285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EL386_RS08295	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EL386_RS08300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EL386_RS08305	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EL386_RS08310	COG1674	ftsk spoiiie
EL386_RS08315	COG0686	Belongs to the AlaDH PNT family
EL386_RS08320	COG0492	ferredoxin-NADP+ reductase activity
EL386_RS08340	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EL386_RS08345	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EL386_RS08355	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EL386_RS08360	COG0542	response to heat
EL386_RS08365	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EL386_RS08370	COG1278	Cold shock
EL386_RS08400	COG0482	sulfurtransferase activity
EL386_RS08405	COG2915	High frequency lysogenization protein hflD homolog
EL386_RS08415	COG1049	propionate catabolic process, 2-methylcitrate cycle
EL386_RS08430	COG2850	peptidyl-arginine hydroxylation
EL386_RS08460	COG0484	heat shock protein binding
EL386_RS08470	COG0071	Belongs to the small heat shock protein (HSP20) family
EL386_RS08475	COG2920	part of a sulfur-relay system
EL386_RS08480	COG0210	DNA helicase
EL386_RS08490	COG2920	part of a sulfur-relay system
EL386_RS08495	COG0437	4 iron, 4 sulfur cluster binding
EL386_RS08500	COG0243	molybdopterin cofactor binding
EL386_RS08510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EL386_RS08515	COG2223	nitrite transmembrane transporter activity
EL386_RS08520	COG0515	serine threonine protein kinase
EL386_RS08520	COG2815	serine threonine protein kinase
EL386_RS08525	COG1116	anion transmembrane transporter activity
EL386_RS08530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EL386_RS08535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EL386_RS08535	COG1116	anion transmembrane transporter activity
EL386_RS08540	COG3707	response regulator
EL386_RS08545	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EL386_RS08550	COG0746	molybdenum cofactor guanylyltransferase activity
EL386_RS08555	COG0303	'Molybdopterin
EL386_RS08570	COG0776	regulation of translation
EL386_RS08575	COG0072	phenylalanine-tRNA ligase activity
EL386_RS08580	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EL386_RS08585	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EL386_RS08590	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EL386_RS08600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EL386_RS08615	COG1215	transferase activity, transferring glycosyl groups
EL386_RS08625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EL386_RS08645	COG2192	nodulation
EL386_RS08650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EL386_RS08700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EL386_RS08710	COG1045	serine acetyltransferase
EL386_RS08750	COG0166	Belongs to the GPI family
EL386_RS08760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EL386_RS08765	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EL386_RS08775	COG0436	Aminotransferase
EL386_RS08800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EL386_RS08810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EL386_RS08815	COG1215	transferase activity, transferring glycosyl groups
EL386_RS08820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EL386_RS08835	COG1216	Glycosyl transferase, family 2
EL386_RS08855	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EL386_RS08875	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EL386_RS08880	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EL386_RS08895	COG0529	Catalyzes the synthesis of activated sulfate
EL386_RS08905	COG0284	orotidine-5'-phosphate decarboxylase activity
EL386_RS08910	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EL386_RS08920	COG0776	regulation of translation
EL386_RS08935	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EL386_RS08940	COG0287	Prephenate dehydrogenase
EL386_RS08945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EL386_RS08950	COG1605	Chorismate mutase
EL386_RS08950	COG0077	Prephenate dehydratase
EL386_RS08955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EL386_RS08960	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EL386_RS08970	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EL386_RS08975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EL386_RS09000	COG0736	holo-[acyl-carrier-protein] synthase activity
EL386_RS09005	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EL386_RS09010	COG1381	Involved in DNA repair and RecF pathway recombination
EL386_RS09015	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EL386_RS09020	COG0571	ribonuclease III activity
EL386_RS09035	COG0481	GTPase activity
EL386_RS09045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EL386_RS09080	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EL386_RS09095	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EL386_RS09100	COG2009	succinate dehydrogenase
EL386_RS09115	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EL386_RS09125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EL386_RS09135	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EL386_RS09145	COG0436	Aminotransferase
EL386_RS09155	COG4191	Histidine kinase
EL386_RS09170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EL386_RS09175	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EL386_RS09185	COG0585	pseudouridine synthase activity
EL386_RS09190	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EL386_RS09195	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EL386_RS09200	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EL386_RS09205	COG0148	phosphopyruvate hydratase activity
EL386_RS09210	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EL386_RS09215	COG0504	CTP synthase activity
EL386_RS09220	COG0037	tRNA processing
EL386_RS09225	COG0825	malonyl-CoA metabolic process
EL386_RS09240	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EL386_RS09245	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EL386_RS09250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EL386_RS09255	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EL386_RS09265	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EL386_RS09270	COG0750	zinc metalloprotease
EL386_RS09275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EL386_RS09280	COG0575	Belongs to the CDS family
EL386_RS09285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EL386_RS09295	COG0528	UMP kinase activity
EL386_RS09300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EL386_RS09305	COG0052	Belongs to the universal ribosomal protein uS2 family
EL386_RS09310	COG0024	Methionine aminopeptidase
EL386_RS09320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EL386_RS09320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EL386_RS09330	COG0745	RESPONSE REGULATOR receiver
EL386_RS09340	COG0784	Response regulator, receiver
EL386_RS09340	COG2205	protein histidine kinase activity
EL386_RS09340	COG2198	Histidine kinase
EL386_RS09360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EL386_RS09365	COG1120	ATPase activity
EL386_RS09370	COG4206	TonB-dependent receptor
EL386_RS09380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EL386_RS09400	COG2391	methyltransferase activity
EL386_RS09415	COG4464	protein tyrosine phosphatase activity
EL386_RS09420	COG0489	protein tyrosine kinase activity
EL386_RS09420	COG3206	protein involved in exopolysaccharide biosynthesis
EL386_RS09440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EL386_RS09445	COG0297	glycogen (starch) synthase activity
EL386_RS09460	COG1086	Polysaccharide biosynthesis protein
EL386_RS09465	COG0463	Glycosyl transferase, family 2
EL386_RS09475	COG0438	transferase activity, transferring glycosyl groups
EL386_RS09485	COG0438	transferase activity, transferring glycosyl groups
EL386_RS09510	COG0463	Glycosyl transferase, family 2
EL386_RS09510	COG1216	Glycosyl transferase, family 2
EL386_RS09565	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EL386_RS09575	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EL386_RS09590	COG1414	Transcriptional regulator
EL386_RS09615	COG0745	RESPONSE REGULATOR receiver
EL386_RS09620	COG2205	protein histidine kinase activity
EL386_RS09655	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EL386_RS09660	COG0527	aspartate kinase activity
EL386_RS09665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EL386_RS09670	COG2137	regulation of response to DNA damage stimulus
EL386_RS09675	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EL386_RS09695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EL386_RS09705	COG1028	Short-chain dehydrogenase reductase Sdr
EL386_RS09710	COG1309	transcriptional regulator
EL386_RS09750	COG1573	uracil-dna glycosylase
EL386_RS09755	COG2910	NAD(P)H-binding
EL386_RS09770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EL386_RS09775	COG1546	Belongs to the CinA family
EL386_RS09785	COG0517	IMP dehydrogenase activity
EL386_RS09785	COG0516	GMP reductase activity
EL386_RS09795	COG0583	DNA-binding transcription factor activity
EL386_RS09800	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EL386_RS09830	COG0643	Histidine kinase
EL386_RS09830	COG0784	Response regulator, receiver
EL386_RS09830	COG2198	Histidine kinase
EL386_RS09835	COG2201	protein-glutamate methylesterase activity
EL386_RS09840	COG3706	GGDEF domain
EL386_RS09840	COG4251	negative regulation of phosphorylation
EL386_RS09840	COG5001	Diguanylate cyclase
EL386_RS09840	COG2203	Gaf domain
EL386_RS09845	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EL386_RS09855	COG1074	ATP-dependent DNA helicase activity
EL386_RS09860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EL386_RS09865	COG1666	GTP binding
EL386_RS09880	COG0335	large ribosomal subunit rRNA binding
EL386_RS09890	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EL386_RS09895	COG0228	four-way junction DNA binding
EL386_RS09900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EL386_RS09910	COG4137	Cytochrome C assembly protein
EL386_RS09915	COG4536	flavin adenine dinucleotide binding
EL386_RS09965	COG0471	metal ion transport
EL386_RS09965	COG3273	potassium ion transport
EL386_RS09975	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EL386_RS09990	COG2363	Small membrane protein
EL386_RS10015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EL386_RS10020	COG0305	Participates in initiation and elongation during chromosome replication
EL386_RS10025	COG0359	binds to the 23S rRNA
EL386_RS10030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EL386_RS10035	COG0360	Binds together with S18 to 16S ribosomal RNA
EL386_RS10040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EL386_RS10045	COG0557	exoribonuclease II activity
EL386_RS10080	COG0583	DNA-binding transcription factor activity
EL386_RS10120	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EL386_RS10125	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EL386_RS10130	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EL386_RS10135	COG0330	HflC and HflK could
EL386_RS10140	COG0330	HflC and HflK could
EL386_RS10145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EL386_RS10150	COG1923	regulation of RNA biosynthetic process
EL386_RS10160	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EL386_RS10165	COG0860	N-Acetylmuramoyl-L-alanine amidase
EL386_RS10170	COG0802	atpase or kinase
EL386_RS10175	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EL386_RS10175	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EL386_RS10185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL386_RS10200	COG1067	ATP-dependent peptidase activity
EL386_RS10205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EL386_RS10235	COG1022	Amp-dependent synthetase and ligase
EL386_RS10245	COG0328	RNA-DNA hybrid ribonuclease activity
EL386_RS10255	COG0741	lytic transglycosylase activity
EL386_RS10255	COG1388	LysM domain
EL386_RS10260	COG1136	(ABC) transporter
EL386_RS10260	COG4591	ABC-type transport system involved in lipoprotein release permease component
EL386_RS10275	COG5002	protein histidine kinase activity
EL386_RS10295	COG4172	Belongs to the ABC transporter superfamily
EL386_RS10300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EL386_RS10305	COG0601	transmembrane transport
EL386_RS10320	COG1301	dicarboxylic acid transport
EL386_RS10325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EL386_RS10345	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EL386_RS10350	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EL386_RS10355	COG0740	serine-type endopeptidase activity
EL386_RS10360	COG0544	peptidyl-prolyl cis-trans isomerase activity
EL386_RS10400	COG0215	cysteine-tRNA ligase activity
EL386_RS10405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EL386_RS10410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EL386_RS10415	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EL386_RS10425	COG2833	Protein of unknown function (DUF455)
EL386_RS10430	COG2379	hydroxypyruvate reductase
EL386_RS10440	COG0668	transmembrane transport
EL386_RS10455	COG1286	toxin biosynthetic process
EL386_RS10465	COG0285	dihydrofolate synthase activity
EL386_RS10470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EL386_RS10475	COG0159	tryptophan synthase activity
EL386_RS10480	COG0133	tryptophan synthase activity
EL386_RS10485	COG0135	phosphoribosylanthranilate isomerase activity
EL386_RS10580	COG0521	Mo-molybdopterin cofactor biosynthetic process
EL386_RS10585	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EL386_RS10660	COG0473	3-isopropylmalate dehydrogenase activity
EL386_RS10665	COG0066	3-isopropylmalate dehydratase activity
EL386_RS10670	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EL386_RS10680	COG2814	Major facilitator Superfamily
EL386_RS10685	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EL386_RS10695	COG2890	protein-(glutamine-N5) methyltransferase activity
EL386_RS10710	COG1355	regulation of microtubule-based process
EL386_RS10715	COG2078	PFAM AMMECR1 domain protein
EL386_RS10715	COG3885	ferrous iron binding
EL386_RS10720	COG0418	dihydroorotase activity
EL386_RS10725	COG2995	paraquat-inducible protein a
EL386_RS10770	COG4566	intracellular signal transduction
EL386_RS10795	COG0688	phosphatidylethanolamine metabolic process
EL386_RS10800	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EL386_RS10805	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EL386_RS10810	COG1509	lysine 2,3-aminomutase activity
EL386_RS10870	COG1592	Rubrerythrin
EL386_RS10875	COG1722	exodeoxyribonuclease VII activity
EL386_RS10880	COG0142	geranyltranstransferase activity
EL386_RS10885	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EL386_RS10890	COG0720	synthase
EL386_RS10895	COG1469	GTP cyclohydrolase I activity
EL386_RS10900	COG3577	Aspartyl protease
EL386_RS10910	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EL386_RS10920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EL386_RS10925	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EL386_RS10940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EL386_RS10940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EL386_RS10945	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EL386_RS10950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EL386_RS10955	COG2202	Pas domain
EL386_RS10955	COG2205	protein histidine kinase activity
EL386_RS10960	COG0784	Response regulator, receiver
EL386_RS10965	COG4251	negative regulation of phosphorylation
EL386_RS10975	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EL386_RS10980	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EL386_RS10990	COG0840	transmembrane signaling receptor activity
EL386_RS10995	COG0840	transmembrane signaling receptor activity
EL386_RS11000	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EL386_RS11005	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EL386_RS11010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EL386_RS11020	COG2716	regulation of RNA biosynthetic process
EL386_RS11025	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EL386_RS11030	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EL386_RS11070	COG1733	regulation of RNA biosynthetic process
EL386_RS11080	COG2207	Transcriptional regulator
EL386_RS11100	COG0367	asparagine synthase
EL386_RS11120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EL386_RS11125	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EL386_RS11130	COG3842	ATPase activity
EL386_RS11225	COG1196	nuclear chromosome segregation
EL386_RS11225	COG0739	heme binding
EL386_RS11225	COG0741	lytic transglycosylase activity
EL386_RS11255	COG2801	Transposase and inactivated derivatives
EL386_RS11290	COG0129	dihydroxy-acid dehydratase activity
EL386_RS11305	COG0412	Dienelactone hydrolase
EL386_RS11320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EL386_RS11330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EL386_RS11345	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EL386_RS11345	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EL386_RS11350	COG0494	nUDIX hydrolase
EL386_RS11360	COG5001	Diguanylate cyclase
EL386_RS11365	COG2096	Adenosyltransferase
EL386_RS11380	COG3023	N-Acetylmuramoyl-L-alanine amidase
EL386_RS11385	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EL386_RS11390	COG0121	glutamine amidotransferase
EL386_RS11420	COG3577	Aspartyl protease
EL386_RS11425	COG1115	amino acid carrier protein
EL386_RS11480	COG4969	Belongs to the N-Me-Phe pilin family
EL386_RS11515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EL386_RS11520	COG1047	Peptidyl-prolyl cis-trans
EL386_RS11530	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EL386_RS11535	COG0196	riboflavin kinase activity
EL386_RS11540	COG0728	peptidoglycan biosynthetic process
EL386_RS11610	COG3604	Transcriptional regulator
EL386_RS11620	COG1136	(ABC) transporter
EL386_RS11625	COG0577	efflux transmembrane transporter activity
EL386_RS11640	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EL386_RS11645	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EL386_RS11655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EL386_RS11660	COG0142	geranyltranstransferase activity
EL386_RS11670	COG0629	single-stranded DNA binding
EL386_RS11680	COG2814	Major facilitator Superfamily
EL386_RS11685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EL386_RS11710	COG0202	RNA polymerase activity
EL386_RS11715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EL386_RS11720	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EL386_RS11725	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EL386_RS11730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EL386_RS11735	COG0201	protein transport
EL386_RS11740	COG0200	Binds to the 23S rRNA
EL386_RS11745	COG1841	ribosomal large subunit assembly
EL386_RS11750	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EL386_RS11755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EL386_RS11760	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EL386_RS11765	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EL386_RS11770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EL386_RS11775	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EL386_RS11780	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EL386_RS11785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EL386_RS11790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EL386_RS11795	COG0255	Belongs to the universal ribosomal protein uL29 family
EL386_RS11800	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EL386_RS11805	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EL386_RS11810	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EL386_RS11815	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EL386_RS11820	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EL386_RS11825	COG0089	rRNA binding
EL386_RS11830	COG0088	Forms part of the polypeptide exit tunnel
EL386_RS11835	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EL386_RS11840	COG0051	transcription antitermination factor activity, RNA binding
EL386_RS11845	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EL386_RS11850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EL386_RS11855	COG0049	tRNA binding
EL386_RS11860	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EL386_RS11865	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EL386_RS11870	COG0085	RNA polymerase activity
EL386_RS11875	COG0222	ribosome binding
EL386_RS11880	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EL386_RS11885	COG0081	regulation of translation
EL386_RS11890	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EL386_RS11910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EL386_RS11940	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EL386_RS11945	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EL386_RS11945	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EL386_RS11960	COG2205	protein histidine kinase activity
EL386_RS11980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EL386_RS11990	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EL386_RS12000	COG0704	Plays a role in the regulation of phosphate uptake
EL386_RS12010	COG0573	inorganic phosphate transmembrane transporter activity
EL386_RS12035	COG0745	RESPONSE REGULATOR receiver
EL386_RS12070	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EL386_RS12080	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EL386_RS12090	COG2983	Belongs to the UPF0260 family
EL386_RS12095	COG1940	carbohydrate kinase activity
EL386_RS12105	COG0484	heat shock protein binding
EL386_RS12110	COG2205	protein histidine kinase activity
EL386_RS12140	COG1217	gtp-binding protein TYPA
EL386_RS12155	COG0835	chemotaxis
EL386_RS12155	COG0784	Response regulator, receiver
EL386_RS12160	COG2900	Belongs to the SlyX family
EL386_RS12165	COG0488	(ABC) transporter
EL386_RS12180	COG1012	belongs to the aldehyde dehydrogenase family
EL386_RS12185	COG0069	glutamate synthase activity
EL386_RS12215	COG1278	Cold shock
EL386_RS12230	COG0501	Belongs to the peptidase M48B family
EL386_RS12235	COG3100	YcgL domain-containing protein
EL386_RS12240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EL386_RS12240	COG0519	Catalyzes the synthesis of GMP from XMP
EL386_RS12260	COG2918	glutathione biosynthetic process
EL386_RS12280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EL386_RS12285	COG1454	alcohol dehydrogenase
EL386_RS12330	COG1047	Peptidyl-prolyl cis-trans
EL386_RS12350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL386_RS12355	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EL386_RS12360	COG0084	hydrolase, TatD family'
EL386_RS12375	COG3956	TIGRFAM MazG family protein
EL386_RS12380	COG5002	protein histidine kinase activity
EL386_RS12380	COG2205	protein histidine kinase activity
EL386_RS12380	COG0784	Response regulator, receiver
EL386_RS12390	COG0563	adenylate kinase activity
EL386_RS12400	COG3264	Mechanosensitive ion channel
EL386_RS12400	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EL386_RS12405	COG2920	part of a sulfur-relay system
EL386_RS12420	COG0659	secondary active sulfate transmembrane transporter activity
EL386_RS12425	COG1278	Cold shock
EL386_RS12430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EL386_RS12450	COG0488	(ABC) transporter
EL386_RS12455	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
EL386_RS12470	COG0446	pyridine nucleotide-disulphide oxidoreductase
EL386_RS12480	COG2081	HI0933 family
EL386_RS12505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EL386_RS12510	COG0514	ATP-dependent DNA helicase (RecQ)
EL386_RS12585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EL386_RS12590	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EL386_RS12605	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EL386_RS12610	COG1073	alpha beta
EL386_RS12625	COG0446	pyridine nucleotide-disulphide oxidoreductase
EL386_RS12645	COG0488	(ABC) transporter
EL386_RS12655	COG1830	Aldolase
EL386_RS12660	COG3360	Dodecin
EL386_RS12665	COG5002	protein histidine kinase activity
EL386_RS12685	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EL386_RS12725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL386_RS12730	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EL386_RS12740	COG0741	lytic transglycosylase activity
EL386_RS12750	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
EL386_RS12760	COG0483	inositol monophosphate 1-phosphatase activity
EL386_RS12790	COG2832	Protein of unknown function (DUF454)
EL386_RS12795	COG0475	glutathione-regulated potassium exporter activity
EL386_RS12795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EL386_RS12800	COG2738	Putative neutral zinc metallopeptidase
EL386_RS12825	COG0826	peptidase U32
EL386_RS12855	COG0596	Alpha beta hydrolase
EL386_RS12860	COG3302	dmso reductase anchor subunit
EL386_RS12865	COG0437	4 iron, 4 sulfur cluster binding
EL386_RS12870	COG0243	molybdopterin cofactor binding
EL386_RS12875	COG0659	secondary active sulfate transmembrane transporter activity
EL386_RS12915	COG0784	Response regulator, receiver
EL386_RS12915	COG2205	protein histidine kinase activity
EL386_RS12915	COG5002	protein histidine kinase activity
EL386_RS12925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EL386_RS12935	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EL386_RS12965	COG2866	Carboxypeptidase
EL386_RS12975	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EL386_RS12990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL386_RS12995	COG1981	membrane
EL386_RS13000	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EL386_RS13005	COG1181	Belongs to the D-alanine--D-alanine ligase family
EL386_RS13010	COG0316	Belongs to the HesB IscA family
EL386_RS13020	COG1730	sister chromatid segregation
EL386_RS13040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EL386_RS13045	COG1773	rubredoxin
EL386_RS13050	COG0351	phosphomethylpyrimidine kinase
EL386_RS13055	COG0352	thiamine-phosphate diphosphorylase activity
EL386_RS13060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EL386_RS13095	COG0583	DNA-binding transcription factor activity
EL386_RS13100	COG0840	transmembrane signaling receptor activity
EL386_RS13115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EL386_RS13125	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EL386_RS13140	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EL386_RS13145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EL386_RS13160	COG0563	adenylate kinase activity
EL386_RS13170	COG0205	6-phosphofructokinase activity
EL386_RS13180	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EL386_RS13190	COG3423	Transcriptional regulator
EL386_RS13205	COG2801	Transposase and inactivated derivatives
EL386_RS13275	COG0653	protein targeting
EL386_RS13290	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EL386_RS13320	COG4373	Mu-like prophage FluMu protein gp28
EL386_RS13330	COG2369	cell adhesion
EL386_RS13345	COG4397	Mu-like prophage major head subunit gpT
EL386_RS13375	COG4386	tail sheath protein
EL386_RS13400	COG4228	DNA circulation
EL386_RS13400	COG4228	DNA circulation
EL386_RS13410	COG4384	Bacteriophage Mu Gp45 protein
EL386_RS13415	COG4381	Mu-like prophage protein gp46
EL386_RS13455	COG0314	molybdopterin synthase activity
EL386_RS13460	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EL386_RS13465	COG0315	cyclic pyranopterin monophosphate synthase activity
EL386_RS13475	COG3066	DNA modification
EL386_RS13480	COG0745	RESPONSE REGULATOR receiver
EL386_RS13495	COG1285	pathogenesis
EL386_RS13595	COG2234	aminopeptidase activity
EL386_RS13600	COG0189	ligase activity
EL386_RS13615	COG1796	DNA polymerase
EL386_RS13615	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EL386_RS13635	COG2808	Putative FMN-binding domain
EL386_RS13640	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
EL386_RS13650	COG1881	PFAM PEBP family protein
EL386_RS13660	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EL386_RS13685	COG3290	protein histidine kinase activity
EL386_RS13685	COG0840	transmembrane signaling receptor activity
EL386_RS13695	COG1309	transcriptional regulator
EL386_RS13705	COG0778	Nitroreductase
EL386_RS13710	COG3258	Cytochrome c
EL386_RS13715	COG2863	cytochrome
EL386_RS13740	COG0243	molybdopterin cofactor binding
EL386_RS13775	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EL386_RS13790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL386_RS13800	COG0730	response to heat
EL386_RS13830	COG3220	belongs to the UPF0276 family
EL386_RS13835	COG0672	)-iron permease
EL386_RS13860	COG2203	Gaf domain
EL386_RS13860	COG3706	GGDEF domain
EL386_RS13860	COG4251	negative regulation of phosphorylation
EL386_RS13860	COG5001	Diguanylate cyclase
EL386_RS13875	COG2814	Major facilitator Superfamily
EL386_RS13895	COG1131	(ABC) transporter
EL386_RS13900	COG0842	Transport permease protein
EL386_RS13915	COG3655	Transcriptional regulator
EL386_RS13945	COG2308	Evidence 4 Homologs of previously reported genes of
EL386_RS13975	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EL386_RS13980	COG3608	succinylglutamate desuccinylase aspartoacylase
EL386_RS13980	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EL386_RS14140	COG2010	Cytochrome c
EL386_RS14145	COG3258	Cytochrome c
EL386_RS14165	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EL386_RS14165	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EL386_RS14185	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EL386_RS14190	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EL386_RS14195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EL386_RS14200	COG1538	Outer membrane efflux protein
EL386_RS14205	COG1519	Transferase
EL386_RS14210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EL386_RS14215	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EL386_RS14215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EL386_RS14220	COG1560	Kdo2-lipid A biosynthetic process
EL386_RS14255	COG2192	nodulation
EL386_RS14280	COG0438	transferase activity, transferring glycosyl groups
EL386_RS14290	COG0859	PFAM glycosyl transferase family 9
EL386_RS14305	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EL386_RS14320	COG1595	DNA-templated transcription, initiation
EL386_RS14330	COG0459	protein refolding
EL386_RS14335	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EL386_RS14340	COG3030	protein affecting phage T7 exclusion by the F plasmid
EL386_RS14345	COG1324	tolerance protein
EL386_RS14350	COG4232	protein-disulfide reductase activity
EL386_RS14355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL386_RS14360	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EL386_RS14365	COG0511	ligase activity, forming carbon-carbon bonds
EL386_RS14370	COG0439	Biotin carboxylase
EL386_RS14375	COG2264	protein methyltransferase activity
EL386_RS14390	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EL386_RS14395	COG0138	bifunctional purine biosynthesis protein purh
EL386_RS14410	COG0151	Belongs to the GarS family
EL386_RS14440	COG0432	Pfam Uncharacterised protein family UPF0047
EL386_RS14445	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EL386_RS14445	COG0515	serine threonine protein kinase
EL386_RS14470	COG2920	part of a sulfur-relay system
EL386_RS14495	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EL386_RS14500	COG0741	lytic transglycosylase activity
EL386_RS14520	COG0071	Belongs to the small heat shock protein (HSP20) family
EL386_RS14535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EL386_RS14545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EL386_RS14580	COG1714	RDD family
EL386_RS14590	COG0537	adenosine 5'-monophosphoramidase activity
EL386_RS14605	COG1047	Peptidyl-prolyl cis-trans
EL386_RS14665	COG0243	molybdopterin cofactor binding
EL386_RS14695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EL386_RS14700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EL386_RS14705	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EL386_RS14720	COG1959	2 iron, 2 sulfur cluster binding
EL386_RS14730	COG1612	heme a metabolic process
EL386_RS14750	COG0471	metal ion transport
EL386_RS14755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EL386_RS14770	COG0531	amino acid
EL386_RS14775	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EL386_RS14795	COG2046	Belongs to the sulfate adenylyltransferase family
EL386_RS14800	COG0617	tRNA 3'-terminal CCA addition
EL386_RS14815	COG1968	undecaprenyl-diphosphatase activity
EL386_RS14825	COG1028	Short-chain dehydrogenase reductase Sdr
EL386_RS14845	COG1595	DNA-templated transcription, initiation
EL386_RS14860	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EL386_RS14860	COG0302	gtp cyclohydrolase
EL386_RS14865	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EL386_RS14870	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EL386_RS14890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EL386_RS14895	COG1610	YqeY-like protein
EL386_RS14940	COG1331	Highly conserved protein containing a thioredoxin domain
EL386_RS14945	COG0805	protein transport
EL386_RS14950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EL386_RS14955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EL386_RS14960	COG0140	phosphoribosyl-ATP diphosphatase activity
EL386_RS14965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EL386_RS14970	COG0107	imidazoleglycerol-phosphate synthase activity
EL386_RS14975	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EL386_RS14980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EL386_RS14985	COG0131	Imidazoleglycerol-phosphate dehydratase
EL386_RS14990	COG3047	cAMP biosynthetic process
EL386_RS14995	COG1490	D-aminoacyl-tRNA deacylase activity
EL386_RS15010	COG1639	'signal transduction protein
EL386_RS15015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EL386_RS15065	COG1410	methionine synthase
EL386_RS15065	COG0646	methionine synthase
EL386_RS15080	COG0330	HflC and HflK could
EL386_RS15100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EL386_RS15105	COG0569	domain protein
EL386_RS15110	COG2204	response regulator
EL386_RS15115	COG5000	phosphorelay sensor kinase activity
EL386_RS15125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EL386_RS15125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EL386_RS15130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EL386_RS15135	COG0242	peptide deformylase activity
EL386_RS15145	COG0758	DNA mediated transformation
EL386_RS15150	COG2922	Belongs to the Smg family
EL386_RS15165	COG0408	coproporphyrinogen oxidase activity
EL386_RS15170	COG2130	NADP-dependent
EL386_RS15185	COG3813	Protein conserved in bacteria
EL386_RS15195	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EL386_RS15195	COG2199	diguanylate cyclase activity
EL386_RS15200	COG0385	Bile acid
EL386_RS15210	COG1392	Phosphate transport regulator
EL386_RS15215	COG0306	phosphate transporter
EL386_RS15220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EL386_RS15230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EL386_RS15245	COG0339	signal peptide processing
EL386_RS15255	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EL386_RS15295	COG1271	oxidase subunit
EL386_RS15305	COG0543	2 iron, 2 sulfur cluster binding
EL386_RS15305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EL386_RS15315	COG2959	enzyme of heme biosynthesis
EL386_RS15325	COG0181	hydroxymethylbilane synthase activity
EL386_RS15340	COG3275	phosphorelay sensor kinase activity
EL386_RS15345	COG0165	Argininosuccinate lyase
EL386_RS15380	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EL386_RS15385	COG5001	Diguanylate cyclase
EL386_RS15385	COG5002	protein histidine kinase activity
EL386_RS15390	COG0210	DNA helicase
EL386_RS15400	COG0542	response to heat
EL386_RS15415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EL386_RS15420	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EL386_RS15425	COG1047	Peptidyl-prolyl cis-trans
EL386_RS15430	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EL386_RS15435	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EL386_RS15440	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EL386_RS15445	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EL386_RS15450	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EL386_RS15455	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EL386_RS15465	COG0356	it plays a direct role in the translocation of protons across the membrane
EL386_RS15475	COG1475	DNA binding
EL386_RS15480	COG1192	Involved in chromosome partitioning
EL386_RS15485	COG0357	Ribosomal RNA small subunit methyltransferase G
EL386_RS15495	COG0445	tRNA wobble uridine modification
EL386_RS15520	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EL386_RS15525	COG0706	membrane insertase activity
EL386_RS15530	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EL386_RS15535	COG0594	ribonuclease P activity