locus-tag	class	description
SUDEN_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SUDEN_RS00010	COG0592	DNA-directed DNA polymerase activity
SUDEN_RS00015	COG0187	DNA topoisomerase II activity
SUDEN_RS00020	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SUDEN_RS00025	COG0617	tRNA 3'-terminal CCA addition
SUDEN_RS00030	COG1217	gtp-binding protein TYPA
SUDEN_RS00035	COG4771	TonB-dependent receptor
SUDEN_RS00045	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS00060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SUDEN_RS00060	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SUDEN_RS00065	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SUDEN_RS00070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SUDEN_RS00105	COG0232	Belongs to the dGTPase family. Type 2 subfamily
SUDEN_RS00110	COG0358	DNA primase activity
SUDEN_RS00120	COG0513	Belongs to the DEAD box helicase family
SUDEN_RS00125	COG0482	sulfurtransferase activity
SUDEN_RS00145	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SUDEN_RS00150	COG1749	Flagellar hook protein flgE
SUDEN_RS00155	COG1749	Flagellar hook protein flgE
SUDEN_RS00160	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SUDEN_RS00165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SUDEN_RS00170	COG1238	metal cluster binding
SUDEN_RS00190	COG1666	GTP binding
SUDEN_RS00210	COG1032	radical SAM domain protein
SUDEN_RS00225	COG2814	Major facilitator Superfamily
SUDEN_RS00235	COG0668	transmembrane transport
SUDEN_RS00260	COG3746	phosphate-selective porin O and P
SUDEN_RS00275	COG0280	phosphate acetyltransferase
SUDEN_RS00275	COG0857	belongs to the CobB CobQ family
SUDEN_RS00280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SUDEN_RS00310	COG0310	cobalt ion transport
SUDEN_RS00320	COG1122	ATPase activity
SUDEN_RS00345	COG0129	dihydroxy-acid dehydratase activity
SUDEN_RS00355	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SUDEN_RS00365	COG1132	(ABC) transporter
SUDEN_RS00370	COG2814	Major facilitator Superfamily
SUDEN_RS00375	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SUDEN_RS00380	COG1968	undecaprenyl-diphosphatase activity
SUDEN_RS00385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SUDEN_RS00390	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SUDEN_RS00395	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SUDEN_RS00420	COG0505	Belongs to the CarA family
SUDEN_RS00425	COG3278	Belongs to the heme-copper respiratory oxidase family
SUDEN_RS00465	COG4628	conserved protein (DUF2132)
SUDEN_RS00470	COG1074	ATP-dependent DNA helicase activity
SUDEN_RS00480	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SUDEN_RS00485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SUDEN_RS00490	COG0747	negative chemotaxis
SUDEN_RS00500	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SUDEN_RS00505	COG1144	Oxidoreductase
SUDEN_RS00510	COG0674	pyruvate-flavodoxin oxidoreductase activity
SUDEN_RS00515	COG1013	pyruvate-flavodoxin oxidoreductase activity
SUDEN_RS00545	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SUDEN_RS00550	COG0668	transmembrane transport
SUDEN_RS00560	COG0406	alpha-ribazole phosphatase activity
SUDEN_RS00565	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SUDEN_RS00580	COG1944	ATP diphosphatase activity
SUDEN_RS00585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SUDEN_RS00590	COG1122	ATPase activity
SUDEN_RS00595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SUDEN_RS00635	COG0575	Belongs to the CDS family
SUDEN_RS00640	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SUDEN_RS00665	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SUDEN_RS00670	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SUDEN_RS00680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SUDEN_RS00685	COG2183	response to ionizing radiation
SUDEN_RS00700	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SUDEN_RS00710	COG1322	Protein conserved in bacteria
SUDEN_RS00715	COG0513	Belongs to the DEAD box helicase family
SUDEN_RS00720	COG1451	nucleotide metabolic process
SUDEN_RS00725	COG0488	(ABC) transporter
SUDEN_RS00735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SUDEN_RS00745	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SUDEN_RS00745	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SUDEN_RS00755	COG1393	Belongs to the ArsC family
SUDEN_RS00770	COG1959	2 iron, 2 sulfur cluster binding
SUDEN_RS00790	COG0175	sulfate reduction
SUDEN_RS00795	COG0175	sulfate reduction
SUDEN_RS00800	COG2895	sulfate adenylyltransferase (ATP) activity
SUDEN_RS00820	COG0288	reversible hydration of carbon dioxide
SUDEN_RS00825	COG0367	asparagine synthase
SUDEN_RS00835	COG0492	ferredoxin-NADP+ reductase activity
SUDEN_RS00850	COG0569	domain protein
SUDEN_RS00850	COG0475	glutathione-regulated potassium exporter activity
SUDEN_RS00855	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SUDEN_RS00865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SUDEN_RS00870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SUDEN_RS00875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SUDEN_RS00885	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SUDEN_RS00890	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SUDEN_RS00890	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SUDEN_RS00905	COG1088	dTDP-glucose 4,6-dehydratase activity
SUDEN_RS00910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SUDEN_RS00915	COG3959	Transketolase, thiamine diphosphate binding domain
SUDEN_RS00930	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SUDEN_RS00940	COG0367	asparagine synthase
SUDEN_RS00945	COG0438	transferase activity, transferring glycosyl groups
SUDEN_RS00955	COG2226	methyltransferase
SUDEN_RS00960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SUDEN_RS00965	COG0438	transferase activity, transferring glycosyl groups
SUDEN_RS00975	COG0438	transferase activity, transferring glycosyl groups
SUDEN_RS00995	COG0535	radical SAM domain protein
SUDEN_RS01010	COG0367	asparagine synthase
SUDEN_RS01020	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
SUDEN_RS01040	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SUDEN_RS01045	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SUDEN_RS01050	COG0784	Response regulator, receiver
SUDEN_RS01050	COG2205	protein histidine kinase activity
SUDEN_RS01065	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
SUDEN_RS01065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SUDEN_RS01070	COG1187	pseudouridine synthase activity
SUDEN_RS01075	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SUDEN_RS01075	COG0517	IMP dehydrogenase activity
SUDEN_RS01090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SUDEN_RS01090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SUDEN_RS01095	COG2022	thiamine diphosphate biosynthetic process
SUDEN_RS01100	COG5001	Diguanylate cyclase
SUDEN_RS01100	COG4251	negative regulation of phosphorylation
SUDEN_RS01100	COG2203	Gaf domain
SUDEN_RS01100	COG3706	GGDEF domain
SUDEN_RS01110	COG3706	GGDEF domain
SUDEN_RS01120	COG1115	amino acid carrier protein
SUDEN_RS01310	COG2731	YhcH YjgK YiaL family protein
SUDEN_RS01315	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SUDEN_RS01325	COG0314	molybdopterin synthase activity
SUDEN_RS01330	COG0303	'Molybdopterin
SUDEN_RS01345	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS01350	COG5002	protein histidine kinase activity
SUDEN_RS01405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SUDEN_RS01420	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
SUDEN_RS01445	COG0848	biopolymer transport protein
SUDEN_RS01450	COG0811	peptide transport
SUDEN_RS01455	COG4771	TonB-dependent receptor
SUDEN_RS01460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SUDEN_RS01475	COG0840	transmembrane signaling receptor activity
SUDEN_RS01485	COG0051	transcription antitermination factor activity, RNA binding
SUDEN_RS01490	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SUDEN_RS01495	COG0088	Forms part of the polypeptide exit tunnel
SUDEN_RS01500	COG0089	rRNA binding
SUDEN_RS01505	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SUDEN_RS01510	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SUDEN_RS01515	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SUDEN_RS01520	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SUDEN_RS01525	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SUDEN_RS01530	COG0255	Belongs to the universal ribosomal protein uL29 family
SUDEN_RS01535	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SUDEN_RS01540	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SUDEN_RS01545	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SUDEN_RS01550	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SUDEN_RS01555	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SUDEN_RS01560	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SUDEN_RS01565	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SUDEN_RS01570	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SUDEN_RS01575	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SUDEN_RS01580	COG0200	Binds to the 23S rRNA
SUDEN_RS01585	COG0201	protein transport
SUDEN_RS01590	COG0024	Methionine aminopeptidase
SUDEN_RS01595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SUDEN_RS01625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SUDEN_RS01640	COG5002	protein histidine kinase activity
SUDEN_RS01645	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS01655	COG1368	sulfuric ester hydrolase activity
SUDEN_RS01660	COG1368	sulfuric ester hydrolase activity
SUDEN_RS01675	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SUDEN_RS01680	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SUDEN_RS01685	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SUDEN_RS01690	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SUDEN_RS01695	COG0202	RNA polymerase activity
SUDEN_RS01700	COG0203	ribosomal protein L17
SUDEN_RS01720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SUDEN_RS01730	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SUDEN_RS01735	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SUDEN_RS01745	COG0142	geranyltranstransferase activity
SUDEN_RS01750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SUDEN_RS01770	COG3118	belongs to the thioredoxin family
SUDEN_RS01775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SUDEN_RS01780	COG3022	response to hydroperoxide
SUDEN_RS01805	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SUDEN_RS01810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SUDEN_RS01825	COG0250	Participates in transcription elongation, termination and antitermination
SUDEN_RS01830	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SUDEN_RS01835	COG0081	regulation of translation
SUDEN_RS01840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SUDEN_RS01845	COG0222	ribosome binding
SUDEN_RS01850	COG0085	RNA polymerase activity
SUDEN_RS01855	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SUDEN_RS01860	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SUDEN_RS01865	COG0049	tRNA binding
SUDEN_RS01870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SUDEN_RS01885	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SUDEN_RS01890	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SUDEN_RS01895	COG0768	penicillin binding
SUDEN_RS01905	COG1558	bacterial-type flagellum-dependent cell motility
SUDEN_RS01910	COG1815	bacterial-type flagellum-dependent cell motility
SUDEN_RS01915	COG2165	general secretion pathway protein
SUDEN_RS01925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SUDEN_RS01935	COG0739	heme binding
SUDEN_RS01945	COG0277	FAD linked oxidase domain protein
SUDEN_RS01960	COG0305	Participates in initiation and elongation during chromosome replication
SUDEN_RS01965	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SUDEN_RS01980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SUDEN_RS01985	COG3287	FIST C domain
SUDEN_RS01985	COG2200	EAL domain
SUDEN_RS01985	COG2199	diguanylate cyclase activity
SUDEN_RS02000	COG0357	Ribosomal RNA small subunit methyltransferase G
SUDEN_RS02005	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SUDEN_RS02010	COG0113	porphobilinogen synthase activity
SUDEN_RS02015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SUDEN_RS02045	COG1981	membrane
SUDEN_RS02050	COG1160	GTP binding
SUDEN_RS02075	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
SUDEN_RS02100	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SUDEN_RS02105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SUDEN_RS02110	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SUDEN_RS02115	COG0612	Peptidase, M16
SUDEN_RS02120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SUDEN_RS02125	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SUDEN_RS02150	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
SUDEN_RS02155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SUDEN_RS02160	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SUDEN_RS02165	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS02180	COG0322	excinuclease ABC activity
SUDEN_RS02190	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SUDEN_RS02195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SUDEN_RS02200	COG0519	Catalyzes the synthesis of GMP from XMP
SUDEN_RS02200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SUDEN_RS02230	COG1185	polyribonucleotide nucleotidyltransferase activity
SUDEN_RS02235	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SUDEN_RS02245	COG2354	Protein conserved in bacteria
SUDEN_RS02250	COG0659	secondary active sulfate transmembrane transporter activity
SUDEN_RS02255	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SUDEN_RS02255	COG0662	Cupin 2, conserved barrel domain protein
SUDEN_RS02280	COG0210	DNA helicase
SUDEN_RS02285	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SUDEN_RS02290	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
SUDEN_RS02295	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SUDEN_RS02300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SUDEN_RS02305	COG0739	heme binding
SUDEN_RS02315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SUDEN_RS02325	COG1519	Transferase
SUDEN_RS02330	COG0564	pseudouridine synthase activity
SUDEN_RS02335	COG2827	Endonuclease containing a URI domain
SUDEN_RS02340	COG1671	Belongs to the UPF0178 family
SUDEN_RS02345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SUDEN_RS02350	COG0228	four-way junction DNA binding
SUDEN_RS02360	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SUDEN_RS02365	COG0336	Belongs to the RNA methyltransferase TrmD family
SUDEN_RS02370	COG0335	large ribosomal subunit rRNA binding
SUDEN_RS02395	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
SUDEN_RS02400	COG0542	response to heat
SUDEN_RS02405	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SUDEN_RS02410	COG2873	o-acetylhomoserine
SUDEN_RS02415	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SUDEN_RS02420	COG0540	Belongs to the ATCase OTCase family
SUDEN_RS02425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SUDEN_RS02430	COG5002	protein histidine kinase activity
SUDEN_RS02440	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SUDEN_RS02445	COG0193	aminoacyl-tRNA hydrolase activity
SUDEN_RS02455	COG0019	diaminopimelate decarboxylase activity
SUDEN_RS02465	COG1605	Chorismate mutase
SUDEN_RS02465	COG0077	Prephenate dehydratase
SUDEN_RS02470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SUDEN_RS02480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SUDEN_RS02490	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SUDEN_RS02500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SUDEN_RS02505	COG1002	Type II restriction enzyme, methylase subunits
SUDEN_RS02515	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SUDEN_RS02525	COG3787	Belongs to the UPF0306 family
SUDEN_RS02535	COG4608	Belongs to the ABC transporter superfamily
SUDEN_RS02540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SUDEN_RS02545	COG0204	Acyl-transferase
SUDEN_RS02555	COG0047	phosphoribosylformylglycinamidine synthase activity
SUDEN_RS02560	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SUDEN_RS02565	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SUDEN_RS02570	COG0793	Belongs to the peptidase S41A family
SUDEN_RS02595	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SUDEN_RS02625	COG0306	phosphate transporter
SUDEN_RS02630	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SUDEN_RS02635	COG0776	regulation of translation
SUDEN_RS02660	COG0191	fructose-bisphosphate aldolase activity
SUDEN_RS02670	COG2226	methyltransferase
SUDEN_RS02680	COG0071	Belongs to the small heat shock protein (HSP20) family
SUDEN_RS02685	COG0071	Belongs to the small heat shock protein (HSP20) family
SUDEN_RS02695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SUDEN_RS02700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SUDEN_RS02715	COG0542	response to heat
SUDEN_RS02720	COG0230	Belongs to the bacterial ribosomal protein bL34 family
SUDEN_RS02725	COG0594	ribonuclease P activity
SUDEN_RS02730	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SUDEN_RS02735	COG0706	membrane insertase activity
SUDEN_RS02745	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SUDEN_RS02750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SUDEN_RS02760	COG0569	domain protein
SUDEN_RS02765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SUDEN_RS02770	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS02775	COG2205	protein histidine kinase activity
SUDEN_RS02780	COG1846	Transcriptional regulator
SUDEN_RS02820	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SUDEN_RS02825	COG1466	dna polymerase III delta subunit
SUDEN_RS02830	COG0557	exoribonuclease II activity
SUDEN_RS02850	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SUDEN_RS02855	COG2258	MOSC domain
SUDEN_RS02860	COG0205	6-phosphofructokinase activity
SUDEN_RS02880	COG1408	metallophosphoesterase
SUDEN_RS02885	COG0484	heat shock protein binding
SUDEN_RS02895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SUDEN_RS02910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SUDEN_RS02920	COG0742	ribosomal rna small subunit methyltransferase
SUDEN_RS02925	COG1706	bacterial-type flagellum-dependent cell motility
SUDEN_RS02930	COG3951	Flagellar rod assembly protein muramidase FlgJ
SUDEN_RS02945	COG1256	bacterial-type flagellum assembly
SUDEN_RS02945	COG4786	Flagellar basal body rod
SUDEN_RS02950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SUDEN_RS02955	COG0512	Glutamine amidotransferase of anthranilate synthase
SUDEN_RS03000	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
SUDEN_RS03015	COG2217	Heavy metal translocating P-type atpase
SUDEN_RS03035	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
SUDEN_RS03035	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SUDEN_RS03055	COG1793	dna ligase
SUDEN_RS03060	COG0859	PFAM glycosyl transferase family 9
SUDEN_RS03075	COG0438	transferase activity, transferring glycosyl groups
SUDEN_RS03080	COG0859	PFAM glycosyl transferase family 9
SUDEN_RS03090	COG1132	(ABC) transporter
SUDEN_RS03100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SUDEN_RS03110	COG2089	acid synthase
SUDEN_RS03120	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SUDEN_RS03130	COG1083	cytidylyl-transferase
SUDEN_RS03140	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SUDEN_RS03145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SUDEN_RS03150	COG1028	Short-chain dehydrogenase reductase Sdr
SUDEN_RS03165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SUDEN_RS03170	COG0247	lactate metabolic process
SUDEN_RS03175	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SUDEN_RS03185	COG0513	Belongs to the DEAD box helicase family
SUDEN_RS03190	COG0564	pseudouridine synthase activity
SUDEN_RS03200	COG3706	GGDEF domain
SUDEN_RS03210	COG3153	acetyltransferase
SUDEN_RS03210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SUDEN_RS03215	COG2197	response regulator
SUDEN_RS03225	COG0242	peptide deformylase activity
SUDEN_RS03235	COG0308	aminopeptidase N
SUDEN_RS03245	COG0439	Biotin carboxylase
SUDEN_RS03250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SUDEN_RS03255	COG0418	dihydroorotase activity
SUDEN_RS03260	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS03270	COG0811	peptide transport
SUDEN_RS03275	COG0848	biopolymer transport protein
SUDEN_RS03285	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SUDEN_RS03290	COG0459	protein refolding
SUDEN_RS03295	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SUDEN_RS03315	COG0731	radical SAM domain protein
SUDEN_RS03320	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SUDEN_RS03330	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SUDEN_RS03335	COG2204	response regulator
SUDEN_RS03355	COG0004	ammonium transporteR
SUDEN_RS03365	COG0004	ammonium transporteR
SUDEN_RS03375	COG3706	GGDEF domain
SUDEN_RS03380	COG1218	3'(2'),5'-bisphosphate nucleotidase
SUDEN_RS03405	COG2304	oxidoreductase activity
SUDEN_RS03425	COG0714	Associated with various cellular activities
SUDEN_RS03455	COG0287	Prephenate dehydrogenase
SUDEN_RS03460	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SUDEN_RS03465	COG1077	Cell shape determining protein MreB Mrl
SUDEN_RS03470	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
SUDEN_RS03480	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS03490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SUDEN_RS03500	COG0157	Belongs to the NadC ModD family
SUDEN_RS03505	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SUDEN_RS03520	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SUDEN_RS03530	COG0083	homoserine kinase activity
SUDEN_RS03540	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SUDEN_RS03550	COG0779	Required for maturation of 30S ribosomal subunits
SUDEN_RS03555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SUDEN_RS03555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SUDEN_RS03565	COG1570	exodeoxyribonuclease VII activity
SUDEN_RS03580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SUDEN_RS03585	COG0616	signal peptide processing
SUDEN_RS03590	COG0402	S-adenosylhomocysteine deaminase activity
SUDEN_RS03595	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SUDEN_RS03600	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SUDEN_RS03610	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SUDEN_RS03655	COG1401	restriction endodeoxyribonuclease activity
SUDEN_RS03670	COG1419	protein localization to endoplasmic reticulum
SUDEN_RS03675	COG0455	bacterial-type flagellum organization
SUDEN_RS03685	COG1191	sigma factor activity
SUDEN_RS03695	COG1776	CheC inhibitor of MCP methylation
SUDEN_RS03695	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SUDEN_RS03700	COG1611	Belongs to the LOG family
SUDEN_RS03705	COG0482	sulfurtransferase activity
SUDEN_RS03735	COG0339	signal peptide processing
SUDEN_RS03740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SUDEN_RS03755	COG2116	formate transmembrane transporter activity
SUDEN_RS03760	COG0528	UMP kinase activity
SUDEN_RS03765	COG1758	RNA polymerase activity
SUDEN_RS03775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SUDEN_RS03790	COG2404	hydrolase activity, acting on ester bonds
SUDEN_RS03795	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SUDEN_RS03805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SUDEN_RS03810	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SUDEN_RS03815	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SUDEN_RS03820	COG0727	PFAM Uncharacterised protein family (UPF0153)
SUDEN_RS03830	COG0134	indole-3-glycerol-phosphate synthase activity
SUDEN_RS03840	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
SUDEN_RS03850	COG2203	Gaf domain
SUDEN_RS03850	COG3706	GGDEF domain
SUDEN_RS03850	COG4251	negative regulation of phosphorylation
SUDEN_RS03850	COG5001	Diguanylate cyclase
SUDEN_RS03855	COG0659	secondary active sulfate transmembrane transporter activity
SUDEN_RS03860	COG0525	valine-tRNA ligase activity
SUDEN_RS03870	COG1592	Rubrerythrin
SUDEN_RS03875	COG0210	DNA helicase
SUDEN_RS03885	COG0133	tryptophan synthase activity
SUDEN_RS03920	COG0784	Response regulator, receiver
SUDEN_RS03920	COG2205	protein histidine kinase activity
SUDEN_RS03930	COG0726	polysaccharide deacetylase
SUDEN_RS03930	COG1649	PFAM Uncharacterised BCR, COG1649
SUDEN_RS03935	COG1215	transferase activity, transferring glycosyl groups
SUDEN_RS03945	COG2081	HI0933 family
SUDEN_RS03950	COG1193	negative regulation of DNA recombination
SUDEN_RS03970	COG0436	Aminotransferase
SUDEN_RS03980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SUDEN_RS03995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SUDEN_RS04010	COG1275	C4-dicarboxylate transporter malic acid transport protein
SUDEN_RS04020	COG1714	RDD family
SUDEN_RS04025	COG0517	IMP dehydrogenase activity
SUDEN_RS04025	COG0516	GMP reductase activity
SUDEN_RS04040	COG0154	amidase activity
SUDEN_RS04045	COG3177	Filamentation induced by cAMP protein fic
SUDEN_RS04080	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SUDEN_RS04085	COG1058	Belongs to the CinA family
SUDEN_RS04085	COG1546	Belongs to the CinA family
SUDEN_RS04120	COG0772	Belongs to the SEDS family
SUDEN_RS04125	COG0564	pseudouridine synthase activity
SUDEN_RS04135	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SUDEN_RS04140	COG2884	Cell division ATP-binding protein ftsE
SUDEN_RS04155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SUDEN_RS04165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SUDEN_RS04170	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SUDEN_RS04185	COG2151	metal-sulfur cluster biosynthetic enzyme
SUDEN_RS04195	COG0275	rRNA processing
SUDEN_RS04305	COG1104	cysteine desulfurase activity
SUDEN_RS04310	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SUDEN_RS04320	COG0437	4 iron, 4 sulfur cluster binding
SUDEN_RS04325	COG0243	molybdopterin cofactor binding
SUDEN_RS04325	COG3383	formate dehydrogenase (NAD+) activity
SUDEN_RS04330	COG0243	molybdopterin cofactor binding
SUDEN_RS04355	COG3852	Histidine kinase
SUDEN_RS04365	COG0425	Belongs to the sulfur carrier protein TusA family
SUDEN_RS04370	COG2391	methyltransferase activity
SUDEN_RS04375	COG0709	Synthesizes selenophosphate from selenide and ATP
SUDEN_RS04380	COG1921	L-seryl-tRNASec selenium transferase activity
SUDEN_RS04420	COG0736	holo-[acyl-carrier-protein] synthase activity
SUDEN_RS04425	COG1580	Controls the rotational direction of flagella during chemotaxis
SUDEN_RS04435	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SUDEN_RS04440	COG0552	protein localization to endoplasmic reticulum
SUDEN_RS04455	COG1418	mRNA catabolic process
SUDEN_RS04465	COG0500	methyltransferase
SUDEN_RS04470	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SUDEN_RS04470	COG2050	protein possibly involved in aromatic compounds catabolism
SUDEN_RS04480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SUDEN_RS04485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SUDEN_RS04490	COG1663	tetraacyldisaccharide 4'-kinase activity
SUDEN_RS04495	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SUDEN_RS04500	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
SUDEN_RS04500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SUDEN_RS04520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SUDEN_RS04525	COG0442	prolyl-tRNA aminoacylation
SUDEN_RS04540	COG0181	hydroxymethylbilane synthase activity
SUDEN_RS04545	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SUDEN_RS04555	COG0165	Argininosuccinate lyase
SUDEN_RS04565	COG0537	adenosine 5'-monophosphoramidase activity
SUDEN_RS04570	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SUDEN_RS04575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SUDEN_RS04575	COG0072	phenylalanine-tRNA ligase activity
SUDEN_RS04580	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SUDEN_RS04585	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SUDEN_RS04590	COG1185	polyribonucleotide nucleotidyltransferase activity
SUDEN_RS04590	COG0539	negative regulation of cytoplasmic translation
SUDEN_RS04600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SUDEN_RS04605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SUDEN_RS04615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SUDEN_RS04640	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SUDEN_RS04645	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS04650	COG0642	Histidine kinase
SUDEN_RS04655	COG3437	response regulator, receiver
SUDEN_RS04655	COG0784	Response regulator, receiver
SUDEN_RS04665	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SUDEN_RS04670	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SUDEN_RS04700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SUDEN_RS04705	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SUDEN_RS04710	COG1331	Highly conserved protein containing a thioredoxin domain
SUDEN_RS04715	COG4232	protein-disulfide reductase activity
SUDEN_RS04725	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SUDEN_RS04730	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SUDEN_RS04755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SUDEN_RS04765	COG0343	queuine tRNA-ribosyltransferase activity
SUDEN_RS04770	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SUDEN_RS04775	COG5002	protein histidine kinase activity
SUDEN_RS04775	COG5001	Diguanylate cyclase
SUDEN_RS04780	COG0587	DNA-directed DNA polymerase activity
SUDEN_RS04790	COG1872	DUF167
SUDEN_RS04795	COG1362	aminopeptidase activity
SUDEN_RS04800	COG0642	Histidine kinase
SUDEN_RS04810	COG1333	cytochrome c biogenesis protein
SUDEN_RS04810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SUDEN_RS04820	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SUDEN_RS04860	COG3842	ATPase activity
SUDEN_RS04890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SUDEN_RS04900	COG3275	phosphorelay sensor kinase activity
SUDEN_RS04905	COG3279	Response regulator of the LytR AlgR family
SUDEN_RS04920	COG0582	viral genome integration into host DNA
SUDEN_RS04945	COG3645	SOS response
SUDEN_RS04975	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
SUDEN_RS05045	COG0582	viral genome integration into host DNA
SUDEN_RS05050	COG0824	Thioesterase
SUDEN_RS05060	COG1283	sodium-dependent phosphate transmembrane transporter activity
SUDEN_RS05075	COG0840	transmembrane signaling receptor activity
SUDEN_RS05080	COG2205	protein histidine kinase activity
SUDEN_RS05100	COG0784	Response regulator, receiver
SUDEN_RS05105	COG0835	chemotaxis
SUDEN_RS05120	COG2198	Histidine kinase
SUDEN_RS05120	COG0643	Histidine kinase
SUDEN_RS05130	COG0784	Response regulator, receiver
SUDEN_RS05130	COG2205	protein histidine kinase activity
SUDEN_RS05135	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
SUDEN_RS05140	COG2201	protein-glutamate methylesterase activity
SUDEN_RS05155	COG0840	transmembrane signaling receptor activity
SUDEN_RS05155	COG3290	protein histidine kinase activity
SUDEN_RS05160	COG3437	response regulator, receiver
SUDEN_RS05165	COG0840	transmembrane signaling receptor activity
SUDEN_RS05170	COG2199	diguanylate cyclase activity
SUDEN_RS05170	COG2200	EAL domain
SUDEN_RS05170	COG3287	FIST C domain
SUDEN_RS05185	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS05225	COG0101	tRNA pseudouridine synthase activity
SUDEN_RS05235	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SUDEN_RS05240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SUDEN_RS05245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SUDEN_RS05265	COG0811	peptide transport
SUDEN_RS05270	COG0848	biopolymer transport protein
SUDEN_RS05280	COG4771	TonB-dependent receptor
SUDEN_RS05285	COG4771	TonB-dependent receptor
SUDEN_RS05300	COG3920	Histidine kinase
SUDEN_RS05310	COG0784	Response regulator, receiver
SUDEN_RS05325	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SUDEN_RS05330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SUDEN_RS05340	COG1338	Plays a role in the flagellum-specific transport system
SUDEN_RS05345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SUDEN_RS05355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SUDEN_RS05365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SUDEN_RS05370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SUDEN_RS05380	COG0521	Mo-molybdopterin cofactor biosynthetic process
SUDEN_RS05395	COG2048	Heterodisulfide reductase, subunit B
SUDEN_RS05415	COG0585	pseudouridine synthase activity
SUDEN_RS05425	COG2201	protein-glutamate methylesterase activity
SUDEN_RS05435	COG3706	GGDEF domain
SUDEN_RS05445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SUDEN_RS05450	COG1196	nuclear chromosome segregation
SUDEN_RS05450	COG1674	ftsk spoiiie
SUDEN_RS05460	COG1049	propionate catabolic process, 2-methylcitrate cycle
SUDEN_RS05470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
SUDEN_RS05475	COG0653	protein targeting
SUDEN_RS05490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SUDEN_RS05500	COG0039	L-malate dehydrogenase activity
SUDEN_RS05505	COG0114	fumarate hydratase activity
SUDEN_RS05510	COG0045	succinate-CoA ligase (ADP-forming) activity
SUDEN_RS05515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SUDEN_RS05525	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SUDEN_RS05525	COG0674	pyruvate-flavodoxin oxidoreductase activity
SUDEN_RS05530	COG1013	pyruvate-flavodoxin oxidoreductase activity
SUDEN_RS05540	COG1309	transcriptional regulator
SUDEN_RS05555	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS05565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SUDEN_RS05585	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SUDEN_RS05595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SUDEN_RS05595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SUDEN_RS05605	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SUDEN_RS05620	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SUDEN_RS05630	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SUDEN_RS05640	COG0768	penicillin binding
SUDEN_RS05655	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SUDEN_RS05670	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SUDEN_RS05675	COG0131	Imidazoleglycerol-phosphate dehydratase
SUDEN_RS05680	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SUDEN_RS05690	COG0084	hydrolase, TatD family'
SUDEN_RS05695	COG0497	DNA recombination
SUDEN_RS05700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SUDEN_RS05705	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SUDEN_RS05710	COG0563	adenylate kinase activity
SUDEN_RS05715	COG0563	adenylate kinase activity
SUDEN_RS05740	COG2171	N-acyltransferase activity
SUDEN_RS05765	COG0788	formyltetrahydrofolate deformylase activity
SUDEN_RS05780	COG0473	3-isopropylmalate dehydrogenase activity
SUDEN_RS05785	COG0066	3-isopropylmalate dehydratase activity
SUDEN_RS05790	COG4786	Flagellar basal body rod
SUDEN_RS05800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SUDEN_RS05820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SUDEN_RS05840	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SUDEN_RS05845	COG0681	Belongs to the peptidase S26 family
SUDEN_RS05850	COG1994	Peptidase M50
SUDEN_RS05855	COG0698	ribose 5-phosphate isomerase
SUDEN_RS05865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SUDEN_RS05870	COG0133	tryptophan synthase activity
SUDEN_RS05875	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SUDEN_RS05885	COG0012	GTP binding
SUDEN_RS05895	COG0163	prenyltransferase activity
SUDEN_RS05900	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SUDEN_RS05905	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SUDEN_RS05915	COG2205	protein histidine kinase activity
SUDEN_RS05920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SUDEN_RS05925	COG0124	histidyl-tRNA synthetase
SUDEN_RS05930	COG0069	glutamate synthase activity
SUDEN_RS05935	COG1166	arginine decarboxylase activity
SUDEN_RS05940	COG1045	serine acetyltransferase
SUDEN_RS05945	COG0436	Aminotransferase
SUDEN_RS05965	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SUDEN_RS05970	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SUDEN_RS05975	COG0440	acetolactate synthase activity
SUDEN_RS05980	COG0028	Belongs to the TPP enzyme family
SUDEN_RS05990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SUDEN_RS05995	COG1832	CoA-binding protein
SUDEN_RS06000	COG0471	metal ion transport
SUDEN_RS06015	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SUDEN_RS06020	COG1137	ATPase activity
SUDEN_RS06025	COG0802	atpase or kinase
SUDEN_RS06030	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SUDEN_RS06050	COG1227	inorganic diphosphatase activity
SUDEN_RS06055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SUDEN_RS06065	COG0778	Nitroreductase
SUDEN_RS06075	COG3012	SEC-C Motif Domain Protein
SUDEN_RS06080	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SUDEN_RS06085	COG0709	Synthesizes selenophosphate from selenide and ATP
SUDEN_RS06090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SUDEN_RS06095	COG0730	response to heat
SUDEN_RS06120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SUDEN_RS06135	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SUDEN_RS06140	COG0352	thiamine-phosphate diphosphorylase activity
SUDEN_RS06145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SUDEN_RS06150	COG0493	'glutamate synthase
SUDEN_RS06155	COG0067	glutamate synthase
SUDEN_RS06155	COG0070	glutamate synthase
SUDEN_RS06155	COG0069	glutamate synthase activity
SUDEN_RS06165	COG0840	transmembrane signaling receptor activity
SUDEN_RS06170	COG0500	methyltransferase
SUDEN_RS06195	COG1730	sister chromatid segregation
SUDEN_RS06240	COG2274	protein secretion by the type I secretion system
SUDEN_RS06270	COG2199	diguanylate cyclase activity
SUDEN_RS06315	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SUDEN_RS06335	COG1181	Belongs to the D-alanine--D-alanine ligase family
SUDEN_RS06340	COG0632	four-way junction helicase activity
SUDEN_RS06350	COG0728	peptidoglycan biosynthetic process
SUDEN_RS06355	COG0215	cysteine-tRNA ligase activity
SUDEN_RS06360	COG1252	NADH dehydrogenase
SUDEN_RS06375	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SUDEN_RS06385	COG0277	FAD linked oxidase domain protein
SUDEN_RS06390	COG0300	oxidoreductase activity
SUDEN_RS06405	COG2267	carboxylic ester hydrolase activity
SUDEN_RS06410	COG2217	Heavy metal translocating P-type atpase
SUDEN_RS06415	COG0167	dihydroorotate dehydrogenase activity
SUDEN_RS06425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SUDEN_RS06430	COG1028	Short-chain dehydrogenase reductase Sdr
SUDEN_RS06445	COG0484	heat shock protein binding
SUDEN_RS06450	COG0584	glycerophosphoryl diester phosphodiesterase
SUDEN_RS06455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SUDEN_RS06460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SUDEN_RS06465	COG0750	zinc metalloprotease
SUDEN_RS06470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SUDEN_RS06480	COG2081	HI0933 family
SUDEN_RS06485	COG0352	thiamine-phosphate diphosphorylase activity
SUDEN_RS06490	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SUDEN_RS06490	COG1328	CTP reductase activity
SUDEN_RS06505	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SUDEN_RS06510	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS06535	COG4974	Belongs to the 'phage' integrase family
SUDEN_RS06550	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SUDEN_RS06570	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SUDEN_RS06575	COG0243	molybdopterin cofactor binding
SUDEN_RS06585	COG0835	chemotaxis
SUDEN_RS06585	COG0784	Response regulator, receiver
SUDEN_RS06595	COG0511	ligase activity, forming carbon-carbon bonds
SUDEN_RS06595	COG5016	pyruvate
SUDEN_RS06600	COG3630	sodium ion export across plasma membrane
SUDEN_RS06605	COG2814	Major facilitator Superfamily
SUDEN_RS06620	COG0326	Molecular chaperone. Has ATPase activity
SUDEN_RS06635	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
SUDEN_RS06640	COG0488	(ABC) transporter
SUDEN_RS06645	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
SUDEN_RS06650	COG3706	GGDEF domain
SUDEN_RS06665	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SUDEN_RS06670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SUDEN_RS06685	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SUDEN_RS06690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SUDEN_RS06695	COG0667	Aldo Keto reductase
SUDEN_RS06700	COG1216	Glycosyl transferase, family 2
SUDEN_RS06700	COG0438	transferase activity, transferring glycosyl groups
SUDEN_RS06715	COG2853	Lipoprotein
SUDEN_RS06720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SUDEN_RS06725	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
SUDEN_RS06730	COG0484	heat shock protein binding
SUDEN_RS06740	COG0640	Transcriptional regulator
SUDEN_RS06750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SUDEN_RS06765	COG0849	cell division
SUDEN_RS06770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SUDEN_RS06790	COG4263	nitrous-oxide reductase activity
SUDEN_RS06805	COG0437	4 iron, 4 sulfur cluster binding
SUDEN_RS06820	COG0348	domain, Protein
SUDEN_RS06825	COG1126	abc transporter atp-binding protein
SUDEN_RS06860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SUDEN_RS06875	COG1136	(ABC) transporter
SUDEN_RS06905	COG0501	Belongs to the peptidase M48B family
SUDEN_RS06910	COG1752	Esterase of the alpha-beta hydrolase superfamily
SUDEN_RS06920	COG0753	catalase activity
SUDEN_RS06930	COG0471	metal ion transport
SUDEN_RS06935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SUDEN_RS06945	COG3706	GGDEF domain
SUDEN_RS06955	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SUDEN_RS06965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SUDEN_RS06970	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SUDEN_RS07000	COG0356	it plays a direct role in the translocation of protons across the membrane
SUDEN_RS07005	COG0585	pseudouridine synthase activity
SUDEN_RS07010	COG0196	riboflavin kinase activity
SUDEN_RS07015	COG2239	Acts as a magnesium transporter
SUDEN_RS07025	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SUDEN_RS07040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SUDEN_RS07110	COG5001	Diguanylate cyclase
SUDEN_RS07130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SUDEN_RS07150	COG0642	Histidine kinase
SUDEN_RS07170	COG2354	Protein conserved in bacteria
SUDEN_RS07185	COG0137	argininosuccinate synthase activity
SUDEN_RS07195	COG0359	binds to the 23S rRNA
SUDEN_RS07200	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SUDEN_RS07205	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SUDEN_RS07240	COG1450	Type ii and iii secretion system protein
SUDEN_RS07255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SUDEN_RS07260	COG1459	type II secretion system
SUDEN_RS07265	COG0217	transcriptional regulatory protein
SUDEN_RS07275	COG0037	tRNA processing
SUDEN_RS07280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SUDEN_RS07285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SUDEN_RS07290	COG2204	response regulator
SUDEN_RS07295	COG1047	Peptidyl-prolyl cis-trans
SUDEN_RS07310	COG0823	Involved in the tonB-independent uptake of proteins
SUDEN_RS07320	COG0848	biopolymer transport protein
SUDEN_RS07325	COG0811	peptide transport
SUDEN_RS07330	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SUDEN_RS07335	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SUDEN_RS07340	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SUDEN_RS07345	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SUDEN_RS07350	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SUDEN_RS07355	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SUDEN_RS07365	COG1475	DNA binding
SUDEN_RS07370	COG1192	Involved in chromosome partitioning
SUDEN_RS07380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SUDEN_RS07385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SUDEN_RS07390	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SUDEN_RS07395	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SUDEN_RS07400	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SUDEN_RS07415	COG0438	transferase activity, transferring glycosyl groups
SUDEN_RS07435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SUDEN_RS07440	COG0375	protein maturation
SUDEN_RS07445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SUDEN_RS07445	COG1024	Enoyl-CoA hydratase
SUDEN_RS07450	COG0309	Hydrogenase expression formation protein (HypE)
SUDEN_RS07465	COG0409	Hydrogenase expression formation protein
SUDEN_RS07470	COG0298	carbon dioxide binding
SUDEN_RS07475	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SUDEN_RS07480	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SUDEN_RS07485	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
SUDEN_RS07490	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SUDEN_RS07495	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
SUDEN_RS07500	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
SUDEN_RS07505	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SUDEN_RS07515	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
SUDEN_RS07540	COG0251	oxidation-reduction process
SUDEN_RS07550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SUDEN_RS07555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SUDEN_RS07565	COG0284	orotidine-5'-phosphate decarboxylase activity
SUDEN_RS07570	COG3189	MarR family transcriptional regulator
SUDEN_RS07585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SUDEN_RS07590	COG2176	DNA-directed DNA polymerase activity
SUDEN_RS07620	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS07625	COG5002	protein histidine kinase activity
SUDEN_RS07630	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SUDEN_RS07635	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SUDEN_RS07640	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SUDEN_RS07645	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SUDEN_RS07650	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SUDEN_RS07655	COG1077	Cell shape determining protein MreB Mrl
SUDEN_RS07665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SUDEN_RS07685	COG0754	glutathionylspermidine amidase activity
SUDEN_RS07690	COG0166	Belongs to the GPI family
SUDEN_RS07705	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
SUDEN_RS07710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SUDEN_RS07715	COG1070	Carbohydrate kinase
SUDEN_RS07735	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
SUDEN_RS07740	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
SUDEN_RS07745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SUDEN_RS07755	COG0489	protein tyrosine kinase activity
SUDEN_RS07760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SUDEN_RS07765	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SUDEN_RS07765	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SUDEN_RS07770	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS07775	COG2046	Belongs to the sulfate adenylyltransferase family
SUDEN_RS07810	COG0840	transmembrane signaling receptor activity
SUDEN_RS07810	COG3290	protein histidine kinase activity
SUDEN_RS07825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SUDEN_RS07840	COG2501	S4 domain
SUDEN_RS07850	COG1278	Cold shock
SUDEN_RS07860	COG0579	oxidoreductase
SUDEN_RS07865	COG0488	(ABC) transporter
SUDEN_RS07880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SUDEN_RS07885	COG2203	Gaf domain
SUDEN_RS07885	COG4251	negative regulation of phosphorylation
SUDEN_RS07885	COG5001	Diguanylate cyclase
SUDEN_RS07885	COG3706	GGDEF domain
SUDEN_RS07900	COG0243	molybdopterin cofactor binding
SUDEN_RS07905	COG0437	4 iron, 4 sulfur cluster binding
SUDEN_RS07910	COG0348	domain, Protein
SUDEN_RS07915	COG3043	anaerobic respiration
SUDEN_RS07950	COG0006	proline dipeptidase activity
SUDEN_RS07965	COG1127	ABC transporter
SUDEN_RS07970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SUDEN_RS07975	COG0835	chemotaxis
SUDEN_RS07980	COG0643	Histidine kinase
SUDEN_RS07980	COG0784	Response regulator, receiver
SUDEN_RS07980	COG2198	Histidine kinase
SUDEN_RS07985	COG0835	chemotaxis
SUDEN_RS07985	COG0784	Response regulator, receiver
SUDEN_RS07995	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SUDEN_RS08000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SUDEN_RS08010	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SUDEN_RS08020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SUDEN_RS08025	COG1120	ATPase activity
SUDEN_RS08030	COG0157	Belongs to the NadC ModD family
SUDEN_RS08045	COG0848	biopolymer transport protein
SUDEN_RS08075	COG4774	siderophore transport
SUDEN_RS08080	COG0500	methyltransferase
SUDEN_RS08095	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SUDEN_RS08100	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SUDEN_RS08105	COG0643	Histidine kinase
SUDEN_RS08105	COG0784	Response regulator, receiver
SUDEN_RS08105	COG2198	Histidine kinase
SUDEN_RS08110	COG2201	protein-glutamate methylesterase activity
SUDEN_RS08115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SUDEN_RS08120	COG2205	protein histidine kinase activity
SUDEN_RS08125	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS08135	COG1692	metallophosphoesterase
SUDEN_RS08140	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SUDEN_RS08160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SUDEN_RS08170	COG0739	heme binding
SUDEN_RS08175	COG0285	dihydrofolate synthase activity
SUDEN_RS08190	COG0495	leucyl-tRNA aminoacylation
SUDEN_RS08200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SUDEN_RS08205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SUDEN_RS08210	COG1862	Preprotein translocase
SUDEN_RS08215	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SUDEN_RS08225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SUDEN_RS08230	COG2860	membrane
SUDEN_RS08240	COG1773	rubredoxin
SUDEN_RS08255	COG1858	cytochrome C peroxidase
SUDEN_RS08260	COG1028	Short-chain dehydrogenase reductase Sdr
SUDEN_RS08265	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SUDEN_RS08310	COG1401	restriction endodeoxyribonuclease activity
SUDEN_RS08325	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SUDEN_RS08335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SUDEN_RS08350	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SUDEN_RS08355	COG0135	phosphoribosylanthranilate isomerase activity
SUDEN_RS08360	COG2176	DNA-directed DNA polymerase activity
SUDEN_RS08365	COG0825	malonyl-CoA metabolic process
SUDEN_RS08370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SUDEN_RS08375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SUDEN_RS08380	COG0415	Belongs to the DNA photolyase family
SUDEN_RS08395	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SUDEN_RS08400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SUDEN_RS08405	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SUDEN_RS08410	COG0788	formyltetrahydrofolate deformylase activity
SUDEN_RS08425	COG4974	Belongs to the 'phage' integrase family
SUDEN_RS08520	COG0590	tRNA wobble adenosine to inosine editing
SUDEN_RS08525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SUDEN_RS08530	COG0481	GTPase activity
SUDEN_RS08535	COG1040	competence protein
SUDEN_RS08550	COG5001	Diguanylate cyclase
SUDEN_RS08560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SUDEN_RS08565	COG0443	Heat shock 70 kDa protein
SUDEN_RS08575	COG2199	diguanylate cyclase activity
SUDEN_RS08580	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SUDEN_RS08595	COG0527	aspartate kinase activity
SUDEN_RS08600	COG0494	nUDIX hydrolase
SUDEN_RS08605	COG0840	transmembrane signaling receptor activity
SUDEN_RS08615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SUDEN_RS08620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SUDEN_RS08625	COG0805	protein transport
SUDEN_RS08630	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SUDEN_RS08640	COG2861	carbohydrate metabolic process
SUDEN_RS08645	COG0360	Binds together with S18 to 16S ribosomal RNA
SUDEN_RS08650	COG0629	single-stranded DNA binding
SUDEN_RS08655	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SUDEN_RS08670	COG0560	Phosphoserine phosphatase
SUDEN_RS08680	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SUDEN_RS08695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SUDEN_RS08700	COG2264	protein methyltransferase activity
SUDEN_RS08705	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS08710	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SUDEN_RS08715	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SUDEN_RS08720	COG0840	transmembrane signaling receptor activity
SUDEN_RS08730	COG0628	permease
SUDEN_RS08735	COG2255	four-way junction helicase activity
SUDEN_RS08740	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SUDEN_RS08750	COG0159	tryptophan synthase activity
SUDEN_RS08770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SUDEN_RS08780	COG4067	protein conserved in archaea
SUDEN_RS08780	COG0189	ligase activity
SUDEN_RS08785	COG0189	ligase activity
SUDEN_RS08820	COG0556	nucleotide-excision repair
SUDEN_RS08830	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SUDEN_RS08840	COG0582	viral genome integration into host DNA
SUDEN_RS08855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SUDEN_RS08860	COG0438	transferase activity, transferring glycosyl groups
SUDEN_RS08875	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SUDEN_RS08885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SUDEN_RS08935	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
SUDEN_RS08990	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
SUDEN_RS09005	COG0438	transferase activity, transferring glycosyl groups
SUDEN_RS09030	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SUDEN_RS09030	COG0662	Cupin 2, conserved barrel domain protein
SUDEN_RS09035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SUDEN_RS09040	COG2081	HI0933 family
SUDEN_RS09045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SUDEN_RS09055	COG0668	transmembrane transport
SUDEN_RS09090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SUDEN_RS09100	COG0195	Participates in both transcription termination and antitermination
SUDEN_RS09115	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SUDEN_RS09120	COG0149	triose-phosphate isomerase activity
SUDEN_RS09125	COG0126	phosphoglycerate kinase activity
SUDEN_RS09135	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SUDEN_RS09140	COG0799	negative regulation of ribosome biogenesis
SUDEN_RS09145	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
SUDEN_RS09150	COG0642	Histidine kinase
SUDEN_RS09155	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS09160	COG2193	ferroxidase activity
SUDEN_RS09165	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SUDEN_RS09170	COG1918	ferrous iron import across plasma membrane
SUDEN_RS09180	COG1183	phosphatidylcholine synthase activity
SUDEN_RS09195	COG0513	Belongs to the DEAD box helicase family
SUDEN_RS09210	COG4263	nitrous-oxide reductase activity
SUDEN_RS09215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SUDEN_RS09220	COG0416	fatty acid biosynthetic process
SUDEN_RS09225	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SUDEN_RS09235	COG0105	UTP biosynthetic process
SUDEN_RS09245	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SUDEN_RS09250	COG0450	alkyl hydroperoxide reductase
SUDEN_RS09255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SUDEN_RS09280	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
SUDEN_RS09285	COG4948	Mandelate Racemase Muconate Lactonizing
SUDEN_RS09310	COG2176	DNA-directed DNA polymerase activity
SUDEN_RS09315	COG1757	Na H antiporter
SUDEN_RS09330	COG0018	arginyl-trna synthetase
SUDEN_RS09335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SUDEN_RS09340	COG0194	GDP metabolic process
SUDEN_RS09350	COG1684	flagellar biosynthetic protein fliR
SUDEN_RS09365	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SUDEN_RS09370	COG0052	Belongs to the universal ribosomal protein uS2 family
SUDEN_RS09375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SUDEN_RS09390	COG0586	Pfam SNARE associated Golgi protein
SUDEN_RS09395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SUDEN_RS09400	COG0772	Belongs to the SEDS family
SUDEN_RS09420	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SUDEN_RS09435	COG1007	ATP synthesis coupled electron transport
SUDEN_RS09445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SUDEN_RS09450	COG0713	ATP synthesis coupled electron transport
SUDEN_RS09455	COG0839	Belongs to the complex I subunit 6 family
SUDEN_RS09460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUDEN_RS09465	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SUDEN_RS09470	COG1034	ATP synthesis coupled electron transport
SUDEN_RS09490	COG0649	NAD binding
SUDEN_RS09495	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUDEN_RS09500	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUDEN_RS09505	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SUDEN_RS09515	COG0590	tRNA wobble adenosine to inosine editing
SUDEN_RS09525	COG1222	aaa ATPase
SUDEN_RS09535	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SUDEN_RS09545	COG2314	TM2 domain
SUDEN_RS09560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SUDEN_RS09570	COG0484	heat shock protein binding
SUDEN_RS09585	COG1253	flavin adenine dinucleotide binding
SUDEN_RS09600	COG1355	regulation of microtubule-based process
SUDEN_RS09610	COG3885	ferrous iron binding
SUDEN_RS09610	COG2078	PFAM AMMECR1 domain protein
SUDEN_RS09615	COG1090	epimerase
SUDEN_RS09620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SUDEN_RS09640	COG1028	Short-chain dehydrogenase reductase Sdr
SUDEN_RS09645	COG0752	glycyl-tRNA synthetase alpha subunit
SUDEN_RS09675	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SUDEN_RS09680	COG0826	peptidase U32
SUDEN_RS09690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SUDEN_RS09695	COG3118	belongs to the thioredoxin family
SUDEN_RS09705	COG0492	ferredoxin-NADP+ reductase activity
SUDEN_RS09710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SUDEN_RS09715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SUDEN_RS09720	COG1242	4 iron, 4 sulfur cluster binding
SUDEN_RS09735	COG0140	phosphoribosyl-ATP diphosphatase activity
SUDEN_RS09735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SUDEN_RS09755	COG0446	pyridine nucleotide-disulphide oxidoreductase
SUDEN_RS09765	COG3852	Histidine kinase
SUDEN_RS09785	COG0573	inorganic phosphate transmembrane transporter activity
SUDEN_RS09790	COG0581	inorganic phosphate transmembrane transporter activity
SUDEN_RS09795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SUDEN_RS09805	COG0174	glutamine synthetase
SUDEN_RS09810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SUDEN_RS09820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SUDEN_RS09825	COG0444	Belongs to the ABC transporter superfamily
SUDEN_RS09830	COG0156	8-amino-7-oxononanoate synthase activity
SUDEN_RS09835	COG3706	GGDEF domain
SUDEN_RS09840	COG0424	maF-like protein
SUDEN_RS09850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SUDEN_RS09855	COG1012	belongs to the aldehyde dehydrogenase family
SUDEN_RS09870	COG0792	nuclease activity
SUDEN_RS09875	COG3383	formate dehydrogenase (NAD+) activity
SUDEN_RS09885	COG0460	homoserine dehydrogenase
SUDEN_RS09890	COG0436	Aminotransferase
SUDEN_RS09910	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SUDEN_RS09915	COG0254	rRNA binding
SUDEN_RS09930	COG0303	'Molybdopterin
SUDEN_RS09940	COG0602	queuosine metabolic process
SUDEN_RS09945	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SUDEN_RS09970	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SUDEN_RS09975	COG0723	plastoquinol--plastocyanin reductase activity
SUDEN_RS09985	COG0445	tRNA wobble uridine modification
SUDEN_RS09990	COG3437	response regulator, receiver
SUDEN_RS09995	COG2205	protein histidine kinase activity
SUDEN_RS09995	COG0784	Response regulator, receiver
SUDEN_RS10025	COG0514	ATP-dependent DNA helicase (RecQ)
SUDEN_RS10030	COG0840	transmembrane signaling receptor activity
SUDEN_RS10060	COG1854	S-ribosylhomocysteine lyase activity
SUDEN_RS10065	COG2201	protein-glutamate methylesterase activity
SUDEN_RS10070	COG0457	Tetratricopeptide repeat
SUDEN_RS10070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SUDEN_RS10075	COG2200	EAL domain
SUDEN_RS10075	COG3287	FIST C domain
SUDEN_RS10075	COG2199	diguanylate cyclase activity
SUDEN_RS10090	COG0569	domain protein
SUDEN_RS10090	COG0475	glutathione-regulated potassium exporter activity
SUDEN_RS10095	COG0513	Belongs to the DEAD box helicase family
SUDEN_RS10105	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SUDEN_RS10175	COG4895	conserved protein (DUF2196)
SUDEN_RS10185	COG3706	GGDEF domain
SUDEN_RS10225	COG1028	Short-chain dehydrogenase reductase Sdr
SUDEN_RS10225	COG3347	Dehydrogenase
SUDEN_RS10230	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SUDEN_RS10235	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
SUDEN_RS10260	COG1522	sequence-specific DNA binding
SUDEN_RS10265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SUDEN_RS10265	COG1648	precorrin-2 dehydrogenase activity
SUDEN_RS10305	COG3256	nitric oxide reductase
SUDEN_RS10320	COG0535	radical SAM domain protein
SUDEN_RS10330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SUDEN_RS10330	COG1648	precorrin-2 dehydrogenase activity
SUDEN_RS10335	COG5002	protein histidine kinase activity
SUDEN_RS10340	COG0745	RESPONSE REGULATOR receiver
SUDEN_RS10350	COG1301	dicarboxylic acid transport
SUDEN_RS10355	COG2239	Acts as a magnesium transporter
SUDEN_RS10390	COG0148	phosphopyruvate hydratase activity
SUDEN_RS10395	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SUDEN_RS10405	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
SUDEN_RS10420	COG2906	2 iron, 2 sulfur cluster binding
SUDEN_RS10420	COG0822	iron-sulfur transferase activity
SUDEN_RS10420	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SUDEN_RS10435	COG1187	pseudouridine synthase activity
SUDEN_RS10460	COG3706	GGDEF domain
SUDEN_RS10470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SUDEN_RS10480	COG0746	molybdenum cofactor guanylyltransferase activity
SUDEN_RS10485	COG0315	cyclic pyranopterin monophosphate synthase activity
SUDEN_RS10490	COG2921	Belongs to the UPF0250 family
SUDEN_RS10500	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SUDEN_RS10505	COG0571	ribonuclease III activity
SUDEN_RS10510	COG0328	RNA-DNA hybrid ribonuclease activity
SUDEN_RS10525	COG2855	membrane
SUDEN_RS10540	COG0646	methionine synthase
SUDEN_RS10540	COG1410	methionine synthase
SUDEN_RS10550	COG0606	chelatase, subunit chli
SUDEN_RS10555	COG0242	peptide deformylase activity
SUDEN_RS10565	COG0740	serine-type endopeptidase activity
SUDEN_RS10570	COG0544	peptidyl-prolyl cis-trans isomerase activity
SUDEN_RS10575	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SUDEN_RS10580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SUDEN_RS10595	COG1136	(ABC) transporter
SUDEN_RS10595	COG0577	efflux transmembrane transporter activity
SUDEN_RS10600	COG0577	efflux transmembrane transporter activity
SUDEN_RS10600	COG1136	(ABC) transporter
SUDEN_RS10605	COG0268	Binds directly to 16S ribosomal RNA
SUDEN_RS10610	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SUDEN_RS10615	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SUDEN_RS10620	COG0237	dephospho-CoA kinase activity
SUDEN_RS10625	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SUDEN_RS10640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SUDEN_RS10655	COG2067	long-chain fatty acid transport protein
SUDEN_RS10680	COG0670	Belongs to the BI1 family
SUDEN_RS10685	COG0352	thiamine-phosphate diphosphorylase activity
SUDEN_RS10725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SUDEN_RS10730	COG1121	(ABC) transporter
SUDEN_RS10735	COG3443	Belongs to the bacterial solute-binding protein 9 family
SUDEN_RS10735	COG0803	Belongs to the bacterial solute-binding protein 9 family
SUDEN_RS10740	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SUDEN_RS10745	COG0233	cytoplasmic translational termination
SUDEN_RS10750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SUDEN_RS10755	COG1472	Belongs to the glycosyl hydrolase 3 family
SUDEN_RS10765	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SUDEN_RS10775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SUDEN_RS10790	COG0676	glucose-6-phosphate 1-epimerase activity
SUDEN_RS10810	COG0504	CTP synthase activity
SUDEN_RS10815	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SUDEN_RS10815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SUDEN_RS10825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SUDEN_RS10835	COG1157	protein secretion by the type III secretion system
SUDEN_RS10845	COG0784	Response regulator, receiver
SUDEN_RS10845	COG4191	Histidine kinase
SUDEN_RS10855	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SUDEN_RS10860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SUDEN_RS10865	COG0107	imidazoleglycerol-phosphate synthase activity
SUDEN_RS10875	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SUDEN_RS10880	COG0564	pseudouridine synthase activity
SUDEN_RS10885	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SUDEN_RS10890	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SUDEN_RS10915	COG2200	EAL domain
SUDEN_RS10915	COG2199	diguanylate cyclase activity
SUDEN_RS10915	COG3287	FIST C domain
SUDEN_RS10920	COG3123	guanosine phosphorylase activity
SUDEN_RS10930	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SUDEN_RS10950	COG2200	EAL domain
SUDEN_RS10950	COG3287	FIST C domain
SUDEN_RS10950	COG2199	diguanylate cyclase activity
SUDEN_RS10960	COG0784	Response regulator, receiver
SUDEN_RS10960	COG5002	protein histidine kinase activity
SUDEN_RS10960	COG2198	Histidine kinase
SUDEN_RS10965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SUDEN_RS11000	COG3706	GGDEF domain
SUDEN_RS11020	COG3706	GGDEF domain
SUDEN_RS11050	COG0840	transmembrane signaling receptor activity
SUDEN_RS11080	COG4251	negative regulation of phosphorylation
SUDEN_RS11080	COG3706	GGDEF domain
SUDEN_RS11080	COG2203	Gaf domain
SUDEN_RS11080	COG5001	Diguanylate cyclase
SUDEN_RS11130	COG2205	protein histidine kinase activity
SUDEN_RS11130	COG2202	Pas domain