locus-tag	class	description
FJR03_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FJR03_RS00010	COG0592	DNA-directed DNA polymerase activity
FJR03_RS00025	COG0187	DNA topoisomerase II activity
FJR03_RS00035	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FJR03_RS00045	COG0617	tRNA 3'-terminal CCA addition
FJR03_RS00050	COG1217	gtp-binding protein TYPA
FJR03_RS00060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FJR03_RS00095	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FJR03_RS00115	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FJR03_RS00125	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FJR03_RS00145	COG0358	DNA primase activity
FJR03_RS00150	COG0482	sulfurtransferase activity
FJR03_RS00170	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FJR03_RS00180	COG1749	Flagellar hook protein flgE
FJR03_RS00185	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FJR03_RS00190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FJR03_RS00195	COG1238	metal cluster binding
FJR03_RS00200	COG1053	succinate dehydrogenase
FJR03_RS00205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FJR03_RS00210	COG3152	Membrane
FJR03_RS00215	COG1666	GTP binding
FJR03_RS00255	COG2010	Cytochrome c
FJR03_RS00265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FJR03_RS00300	COG2814	Major facilitator Superfamily
FJR03_RS00310	COG0668	transmembrane transport
FJR03_RS00330	COG0840	transmembrane signaling receptor activity
FJR03_RS00335	COG0588	phosphoglycerate mutase activity
FJR03_RS00340	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FJR03_RS00350	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FJR03_RS00405	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FJR03_RS00410	COG1492	cobalamin metabolic process
FJR03_RS00415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FJR03_RS00445	COG0778	Nitroreductase
FJR03_RS00450	COG1797	cobyrinic acid a,c-diamide synthase activity
FJR03_RS00455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FJR03_RS00460	COG1121	(ABC) transporter
FJR03_RS00470	COG4206	TonB-dependent receptor
FJR03_RS00490	COG0575	Belongs to the CDS family
FJR03_RS00495	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FJR03_RS00500	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FJR03_RS00505	COG3706	GGDEF domain
FJR03_RS00510	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FJR03_RS00530	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FJR03_RS00540	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FJR03_RS00545	COG0148	phosphopyruvate hydratase activity
FJR03_RS00565	COG2239	Acts as a magnesium transporter
FJR03_RS00570	COG4536	flavin adenine dinucleotide binding
FJR03_RS00585	COG0367	asparagine synthase
FJR03_RS00590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FJR03_RS00595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FJR03_RS00605	COG0475	glutathione-regulated potassium exporter activity
FJR03_RS00605	COG0569	domain protein
FJR03_RS00610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FJR03_RS00620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FJR03_RS00640	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FJR03_RS00655	COG4221	oxidoreductase activity
FJR03_RS00660	COG0561	phosphatase activity
FJR03_RS00680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FJR03_RS00730	COG3746	phosphate-selective porin O and P
FJR03_RS00745	COG1555	photosystem II stabilization
FJR03_RS00745	COG1596	polysaccharide export
FJR03_RS00750	COG0303	'Molybdopterin
FJR03_RS00755	COG0314	molybdopterin synthase activity
FJR03_RS00765	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FJR03_RS00770	COG0281	malic enzyme
FJR03_RS00770	COG0280	phosphate acetyltransferase
FJR03_RS00780	COG1187	pseudouridine synthase activity
FJR03_RS00785	COG0517	IMP dehydrogenase activity
FJR03_RS00785	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FJR03_RS00795	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FJR03_RS00795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FJR03_RS00800	COG2022	thiamine diphosphate biosynthetic process
FJR03_RS00815	COG1115	amino acid carrier protein
FJR03_RS00850	COG0745	RESPONSE REGULATOR receiver
FJR03_RS00855	COG0840	transmembrane signaling receptor activity
FJR03_RS00870	COG3706	GGDEF domain
FJR03_RS00875	COG4191	Histidine kinase
FJR03_RS00875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FJR03_RS00880	COG4753	response regulator
FJR03_RS00880	COG2207	Transcriptional regulator
FJR03_RS00885	COG0745	RESPONSE REGULATOR receiver
FJR03_RS00890	COG5002	protein histidine kinase activity
FJR03_RS00895	COG3300	MHYT domain
FJR03_RS00895	COG5001	Diguanylate cyclase
FJR03_RS00945	COG0840	transmembrane signaling receptor activity
FJR03_RS00950	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FJR03_RS00955	COG3852	Histidine kinase
FJR03_RS00975	COG0415	Belongs to the DNA photolyase family
FJR03_RS00980	COG1090	epimerase
FJR03_RS00985	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FJR03_RS00995	COG3275	phosphorelay sensor kinase activity
FJR03_RS01000	COG3279	Response regulator of the LytR AlgR family
FJR03_RS01010	COG0051	transcription antitermination factor activity, RNA binding
FJR03_RS01015	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FJR03_RS01020	COG0088	Forms part of the polypeptide exit tunnel
FJR03_RS01025	COG0089	rRNA binding
FJR03_RS01030	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FJR03_RS01035	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FJR03_RS01040	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FJR03_RS01045	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FJR03_RS01050	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FJR03_RS01055	COG0255	Belongs to the universal ribosomal protein uL29 family
FJR03_RS01060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FJR03_RS01065	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FJR03_RS01070	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FJR03_RS01075	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FJR03_RS01080	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FJR03_RS01085	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FJR03_RS01090	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FJR03_RS01095	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FJR03_RS01100	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FJR03_RS01105	COG0200	Binds to the 23S rRNA
FJR03_RS01110	COG0201	protein transport
FJR03_RS01115	COG0024	Methionine aminopeptidase
FJR03_RS01120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FJR03_RS01135	COG0840	transmembrane signaling receptor activity
FJR03_RS01145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FJR03_RS01160	COG0071	Belongs to the small heat shock protein (HSP20) family
FJR03_RS01185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FJR03_RS01190	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FJR03_RS01195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FJR03_RS01200	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FJR03_RS01205	COG0202	RNA polymerase activity
FJR03_RS01210	COG0203	ribosomal protein L17
FJR03_RS01230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FJR03_RS01250	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FJR03_RS01255	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FJR03_RS01265	COG0142	geranyltranstransferase activity
FJR03_RS01270	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FJR03_RS01285	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FJR03_RS01300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FJR03_RS01305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FJR03_RS01310	COG3022	response to hydroperoxide
FJR03_RS01350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FJR03_RS01355	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FJR03_RS01370	COG0250	Participates in transcription elongation, termination and antitermination
FJR03_RS01375	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FJR03_RS01380	COG0081	regulation of translation
FJR03_RS01385	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FJR03_RS01390	COG0222	ribosome binding
FJR03_RS01395	COG0085	RNA polymerase activity
FJR03_RS01400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FJR03_RS01405	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FJR03_RS01410	COG0049	tRNA binding
FJR03_RS01415	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FJR03_RS01435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FJR03_RS01440	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FJR03_RS01455	COG1558	bacterial-type flagellum-dependent cell motility
FJR03_RS01460	COG1815	bacterial-type flagellum-dependent cell motility
FJR03_RS01465	COG2165	general secretion pathway protein
FJR03_RS01475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FJR03_RS01480	COG0494	nUDIX hydrolase
FJR03_RS01485	COG0739	heme binding
FJR03_RS01495	COG0277	FAD linked oxidase domain protein
FJR03_RS01500	COG1295	ribonuclease BN
FJR03_RS01510	COG0305	Participates in initiation and elongation during chromosome replication
FJR03_RS01515	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FJR03_RS01530	COG2957	Belongs to the agmatine deiminase family
FJR03_RS01535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FJR03_RS01540	COG0791	NLP P60 protein
FJR03_RS01555	COG0357	Ribosomal RNA small subunit methyltransferase G
FJR03_RS01560	COG0840	transmembrane signaling receptor activity
FJR03_RS01575	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FJR03_RS01580	COG0113	porphobilinogen synthase activity
FJR03_RS01585	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FJR03_RS01595	COG0745	RESPONSE REGULATOR receiver
FJR03_RS01600	COG0642	Histidine kinase
FJR03_RS01605	COG2863	cytochrome
FJR03_RS01635	COG1981	membrane
FJR03_RS01640	COG1160	GTP binding
FJR03_RS01660	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FJR03_RS01665	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FJR03_RS01685	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FJR03_RS01690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FJR03_RS01705	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FJR03_RS01710	COG0612	Peptidase, M16
FJR03_RS01715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FJR03_RS01735	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FJR03_RS01740	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FJR03_RS01755	COG0772	Belongs to the SEDS family
FJR03_RS01760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FJR03_RS01765	COG0586	Pfam SNARE associated Golgi protein
FJR03_RS01775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FJR03_RS01785	COG0052	Belongs to the universal ribosomal protein uS2 family
FJR03_RS01790	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FJR03_RS01800	COG1136	(ABC) transporter
FJR03_RS01815	COG0194	GDP metabolic process
FJR03_RS01820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FJR03_RS01825	COG0018	arginyl-trna synthetase
FJR03_RS01840	COG1757	Na H antiporter
FJR03_RS01860	COG0697	spore germination
FJR03_RS01875	COG4948	Mandelate Racemase Muconate Lactonizing
FJR03_RS01880	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FJR03_RS01895	COG3864	Putative metallopeptidase domain
FJR03_RS01900	COG2199	diguanylate cyclase activity
FJR03_RS01900	COG2203	Gaf domain
FJR03_RS01915	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FJR03_RS01925	COG0469	pyruvate kinase activity
FJR03_RS01935	COG0450	alkyl hydroperoxide reductase
FJR03_RS01945	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FJR03_RS01955	COG0105	UTP biosynthetic process
FJR03_RS01965	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FJR03_RS01970	COG0416	fatty acid biosynthetic process
FJR03_RS01975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FJR03_RS01980	COG0439	Biotin carboxylase
FJR03_RS01985	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FJR03_RS02000	COG1322	Protein conserved in bacteria
FJR03_RS02035	COG1183	phosphatidylcholine synthase activity
FJR03_RS02055	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FJR03_RS02060	COG0745	RESPONSE REGULATOR receiver
FJR03_RS02065	COG0642	Histidine kinase
FJR03_RS02070	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FJR03_RS02075	COG0799	negative regulation of ribosome biogenesis
FJR03_RS02080	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FJR03_RS02090	COG0126	phosphoglycerate kinase activity
FJR03_RS02095	COG0149	triose-phosphate isomerase activity
FJR03_RS02100	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FJR03_RS02120	COG2081	HI0933 family
FJR03_RS02125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJR03_RS02130	COG0037	tRNA processing
FJR03_RS02165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJR03_RS02175	COG0195	Participates in both transcription termination and antitermination
FJR03_RS02185	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FJR03_RS02190	COG0805	protein transport
FJR03_RS02195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FJR03_RS02205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FJR03_RS02210	COG2205	protein histidine kinase activity
FJR03_RS02220	COG0494	nUDIX hydrolase
FJR03_RS02225	COG0527	aspartate kinase activity
FJR03_RS02240	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FJR03_RS02245	COG3706	GGDEF domain
FJR03_RS02250	COG0306	phosphate transporter
FJR03_RS02255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FJR03_RS02260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FJR03_RS02270	COG0776	regulation of translation
FJR03_RS02290	COG0191	fructose-bisphosphate aldolase activity
FJR03_RS02300	COG2226	methyltransferase
FJR03_RS02310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FJR03_RS02320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FJR03_RS02330	COG0542	response to heat
FJR03_RS02335	COG2199	diguanylate cyclase activity
FJR03_RS02335	COG2200	EAL domain
FJR03_RS02335	COG3287	FIST C domain
FJR03_RS02350	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FJR03_RS02355	COG0594	ribonuclease P activity
FJR03_RS02360	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FJR03_RS02365	COG0706	membrane insertase activity
FJR03_RS02375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FJR03_RS02380	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FJR03_RS02385	COG3287	FIST C domain
FJR03_RS02385	COG2200	EAL domain
FJR03_RS02385	COG2199	diguanylate cyclase activity
FJR03_RS02400	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FJR03_RS02405	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FJR03_RS02410	COG0540	Belongs to the ATCase OTCase family
FJR03_RS02415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FJR03_RS02430	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FJR03_RS02435	COG0193	aminoacyl-tRNA hydrolase activity
FJR03_RS02445	COG0019	diaminopimelate decarboxylase activity
FJR03_RS02455	COG0077	Prephenate dehydratase
FJR03_RS02455	COG1605	Chorismate mutase
FJR03_RS02460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FJR03_RS02465	COG1766	The M ring may be actively involved in energy transduction
FJR03_RS02470	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FJR03_RS02480	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FJR03_RS02495	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FJR03_RS02505	COG3787	Belongs to the UPF0306 family
FJR03_RS02520	COG4608	Belongs to the ABC transporter superfamily
FJR03_RS02525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FJR03_RS02530	COG0204	Acyl-transferase
FJR03_RS02540	COG0047	phosphoribosylformylglycinamidine synthase activity
FJR03_RS02545	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FJR03_RS02550	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FJR03_RS02555	COG0793	Belongs to the peptidase S41A family
FJR03_RS02570	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FJR03_RS02575	COG0303	'Molybdopterin
FJR03_RS02615	COG0443	Heat shock 70 kDa protein
FJR03_RS02620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FJR03_RS02640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FJR03_RS02645	COG0481	GTPase activity
FJR03_RS02650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FJR03_RS02655	COG0735	belongs to the Fur family
FJR03_RS02665	COG0557	exoribonuclease II activity
FJR03_RS02680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FJR03_RS02685	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FJR03_RS02690	COG0004	ammonium transporteR
FJR03_RS02695	COG0347	Belongs to the P(II) protein family
FJR03_RS02710	COG0205	6-phosphofructokinase activity
FJR03_RS02715	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FJR03_RS02720	COG1433	Dinitrogenase iron-molybdenum cofactor
FJR03_RS02730	COG0716	FMN binding
FJR03_RS02755	COG0633	Ferredoxin
FJR03_RS02760	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FJR03_RS02785	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FJR03_RS02795	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FJR03_RS02795	COG0316	Belongs to the HesB IscA family
FJR03_RS02805	COG0426	domain, Protein
FJR03_RS02815	COG1104	cysteine desulfurase activity
FJR03_RS02820	COG0822	iron-sulfur transferase activity
FJR03_RS02820	COG2906	2 iron, 2 sulfur cluster binding
FJR03_RS02820	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FJR03_RS02825	COG0740	serine-type endopeptidase activity
FJR03_RS02835	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FJR03_RS02845	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FJR03_RS02850	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FJR03_RS02860	COG0667	Aldo Keto reductase
FJR03_RS02865	COG1053	succinate dehydrogenase
FJR03_RS02890	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FJR03_RS02910	COG3706	GGDEF domain
FJR03_RS02935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FJR03_RS02965	COG3706	GGDEF domain
FJR03_RS02980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FJR03_RS02985	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FJR03_RS03005	COG0542	response to heat
FJR03_RS03015	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FJR03_RS03015	COG2199	diguanylate cyclase activity
FJR03_RS03030	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FJR03_RS03050	COG2353	YceI-like domain
FJR03_RS03055	COG1741	Belongs to the pirin family
FJR03_RS03075	COG0138	bifunctional purine biosynthesis protein purh
FJR03_RS03090	COG0484	heat shock protein binding
FJR03_RS03100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FJR03_RS03130	COG0742	ribosomal rna small subunit methyltransferase
FJR03_RS03135	COG1706	bacterial-type flagellum-dependent cell motility
FJR03_RS03140	COG3951	Flagellar rod assembly protein muramidase FlgJ
FJR03_RS03155	COG4786	Flagellar basal body rod
FJR03_RS03155	COG1256	bacterial-type flagellum assembly
FJR03_RS03160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FJR03_RS03165	COG0628	permease
FJR03_RS03170	COG1012	belongs to the aldehyde dehydrogenase family
FJR03_RS03175	COG0512	Glutamine amidotransferase of anthranilate synthase
FJR03_RS03220	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FJR03_RS03250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FJR03_RS03255	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FJR03_RS03255	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FJR03_RS03275	COG0859	PFAM glycosyl transferase family 9
FJR03_RS03280	COG0463	Glycosyl transferase, family 2
FJR03_RS03295	COG0438	transferase activity, transferring glycosyl groups
FJR03_RS03300	COG1086	Polysaccharide biosynthesis protein
FJR03_RS03305	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FJR03_RS03335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FJR03_RS03345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FJR03_RS03355	COG2089	acid synthase
FJR03_RS03360	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FJR03_RS03365	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FJR03_RS03370	COG1083	cytidylyl-transferase
FJR03_RS03380	COG0463	Glycosyl transferase, family 2
FJR03_RS03400	COG1132	(ABC) transporter
FJR03_RS03405	COG3437	response regulator, receiver
FJR03_RS03410	COG0784	Response regulator, receiver
FJR03_RS03410	COG2205	protein histidine kinase activity
FJR03_RS03415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FJR03_RS03420	COG0247	lactate metabolic process
FJR03_RS03425	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FJR03_RS03440	COG2199	diguanylate cyclase activity
FJR03_RS03440	COG2200	EAL domain
FJR03_RS03440	COG3287	FIST C domain
FJR03_RS03445	COG0513	Belongs to the DEAD box helicase family
FJR03_RS03450	COG0564	pseudouridine synthase activity
FJR03_RS03455	COG0308	aminopeptidase N
FJR03_RS03475	COG0784	Response regulator, receiver
FJR03_RS03475	COG2205	protein histidine kinase activity
FJR03_RS03475	COG5002	protein histidine kinase activity
FJR03_RS03485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FJR03_RS03505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FJR03_RS03520	COG3290	protein histidine kinase activity
FJR03_RS03520	COG0840	transmembrane signaling receptor activity
FJR03_RS03525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FJR03_RS03530	COG0668	transmembrane transport
FJR03_RS03565	COG0745	RESPONSE REGULATOR receiver
FJR03_RS03570	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FJR03_RS03570	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FJR03_RS03575	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FJR03_RS03580	COG0489	protein tyrosine kinase activity
FJR03_RS03590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FJR03_RS03595	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FJR03_RS03605	COG1028	Short-chain dehydrogenase reductase Sdr
FJR03_RS03605	COG3347	Dehydrogenase
FJR03_RS03610	COG1070	Carbohydrate kinase
FJR03_RS03615	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FJR03_RS03625	COG1287	oligosaccharyl transferase activity
FJR03_RS03635	COG0166	Belongs to the GPI family
FJR03_RS03645	COG0754	glutathionylspermidine amidase activity
FJR03_RS03665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FJR03_RS03680	COG1077	Cell shape determining protein MreB Mrl
FJR03_RS03685	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FJR03_RS03690	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FJR03_RS03695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FJR03_RS03700	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FJR03_RS03705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FJR03_RS03710	COG2205	protein histidine kinase activity
FJR03_RS03710	COG0745	RESPONSE REGULATOR receiver
FJR03_RS03710	COG3292	Two component regulator propeller
FJR03_RS03715	COG0745	RESPONSE REGULATOR receiver
FJR03_RS03725	COG3162	membrane
FJR03_RS03740	COG2176	DNA-directed DNA polymerase activity
FJR03_RS03745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FJR03_RS03755	COG0564	pseudouridine synthase activity
FJR03_RS03760	COG0284	orotidine-5'-phosphate decarboxylase activity
FJR03_RS03785	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FJR03_RS03795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FJR03_RS03810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FJR03_RS03825	COG0217	transcriptional regulatory protein
FJR03_RS03830	COG1739	Uncharacterized protein family UPF0029
FJR03_RS03840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FJR03_RS03860	COG4796	Type ii and iii secretion system protein
FJR03_RS03895	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FJR03_RS03900	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FJR03_RS03905	COG0359	binds to the 23S rRNA
FJR03_RS03915	COG0137	argininosuccinate synthase activity
FJR03_RS03940	COG0534	Mate efflux family protein
FJR03_RS03945	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FJR03_RS03950	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FJR03_RS03955	COG0196	riboflavin kinase activity
FJR03_RS03960	COG0585	pseudouridine synthase activity
FJR03_RS03970	COG0500	methyltransferase
FJR03_RS03975	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FJR03_RS03975	COG2050	protein possibly involved in aromatic compounds catabolism
FJR03_RS03990	COG2833	Protein of unknown function (DUF455)
FJR03_RS03995	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FJR03_RS04000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FJR03_RS04005	COG1663	tetraacyldisaccharide 4'-kinase activity
FJR03_RS04010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FJR03_RS04025	COG0142	geranyltranstransferase activity
FJR03_RS04030	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FJR03_RS04035	COG0442	prolyl-tRNA aminoacylation
FJR03_RS04050	COG0181	hydroxymethylbilane synthase activity
FJR03_RS04055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FJR03_RS04065	COG0339	signal peptide processing
FJR03_RS04075	COG0528	UMP kinase activity
FJR03_RS04080	COG1758	RNA polymerase activity
FJR03_RS04090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FJR03_RS04105	COG2404	hydrolase activity, acting on ester bonds
FJR03_RS04110	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FJR03_RS04120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FJR03_RS04125	COG1979	alcohol dehydrogenase
FJR03_RS04135	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FJR03_RS04140	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FJR03_RS04155	COG0134	indole-3-glycerol-phosphate synthase activity
FJR03_RS04160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FJR03_RS04170	COG0251	oxidation-reduction process
FJR03_RS04190	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FJR03_RS04195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FJR03_RS04200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FJR03_RS04205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FJR03_RS04210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FJR03_RS04215	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FJR03_RS04215	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FJR03_RS04220	COG1192	Involved in chromosome partitioning
FJR03_RS04225	COG1475	DNA binding
FJR03_RS04235	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FJR03_RS04240	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FJR03_RS04245	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FJR03_RS04250	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FJR03_RS04255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FJR03_RS04260	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FJR03_RS04265	COG0811	peptide transport
FJR03_RS04270	COG0848	biopolymer transport protein
FJR03_RS04280	COG0823	Involved in the tonB-independent uptake of proteins
FJR03_RS04285	COG2885	chlorophyll binding
FJR03_RS04295	COG1047	Peptidyl-prolyl cis-trans
FJR03_RS04300	COG2204	response regulator
FJR03_RS04305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FJR03_RS04310	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FJR03_RS04310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FJR03_RS04315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FJR03_RS04320	COG0037	tRNA processing
FJR03_RS04335	COG0516	GMP reductase activity
FJR03_RS04335	COG0517	IMP dehydrogenase activity
FJR03_RS04345	COG0154	amidase activity
FJR03_RS04425	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FJR03_RS04465	COG0840	transmembrane signaling receptor activity
FJR03_RS04470	COG5001	Diguanylate cyclase
FJR03_RS04470	COG5002	protein histidine kinase activity
FJR03_RS04480	COG0772	Belongs to the SEDS family
FJR03_RS04485	COG0564	pseudouridine synthase activity
FJR03_RS04495	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FJR03_RS04500	COG1136	(ABC) transporter
FJR03_RS04515	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FJR03_RS04530	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FJR03_RS04535	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FJR03_RS04540	COG0784	Response regulator, receiver
FJR03_RS04540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FJR03_RS04540	COG2205	protein histidine kinase activity
FJR03_RS04540	COG2198	Histidine kinase
FJR03_RS04545	COG0275	rRNA processing
FJR03_RS04625	COG2391	methyltransferase activity
FJR03_RS04645	COG3287	FIST C domain
FJR03_RS04645	COG2200	EAL domain
FJR03_RS04645	COG2199	diguanylate cyclase activity
FJR03_RS04655	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FJR03_RS04665	COG0165	Argininosuccinate lyase
FJR03_RS04680	COG0537	adenosine 5'-monophosphoramidase activity
FJR03_RS04685	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FJR03_RS04690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJR03_RS04690	COG0072	phenylalanine-tRNA ligase activity
FJR03_RS04695	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FJR03_RS04700	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FJR03_RS04705	COG0539	negative regulation of cytoplasmic translation
FJR03_RS04705	COG1185	polyribonucleotide nucleotidyltransferase activity
FJR03_RS04715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FJR03_RS04730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJR03_RS04760	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FJR03_RS04765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FJR03_RS04780	COG1858	cytochrome C peroxidase
FJR03_RS04785	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FJR03_RS04790	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FJR03_RS04805	COG1331	Highly conserved protein containing a thioredoxin domain
FJR03_RS04825	COG4232	protein-disulfide reductase activity
FJR03_RS04840	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FJR03_RS04845	COG3287	FIST C domain
FJR03_RS04845	COG2199	diguanylate cyclase activity
FJR03_RS04845	COG2200	EAL domain
FJR03_RS04850	COG0343	queuine tRNA-ribosyltransferase activity
FJR03_RS04855	COG0071	Belongs to the small heat shock protein (HSP20) family
FJR03_RS04900	COG0189	ligase activity
FJR03_RS04925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FJR03_RS04930	COG0587	DNA-directed DNA polymerase activity
FJR03_RS04935	COG1362	aminopeptidase activity
FJR03_RS04940	COG0642	Histidine kinase
FJR03_RS04960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FJR03_RS04960	COG1333	cytochrome c biogenesis protein
FJR03_RS04975	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FJR03_RS04995	COG0840	transmembrane signaling receptor activity
FJR03_RS05005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJR03_RS05020	COG1592	Rubrerythrin
FJR03_RS05045	COG2271	Major facilitator Superfamily
FJR03_RS05050	COG1278	Cold shock
FJR03_RS05065	COG0824	Thioesterase
FJR03_RS05075	COG1573	uracil-dna glycosylase
FJR03_RS05080	COG3300	MHYT domain
FJR03_RS05080	COG5001	Diguanylate cyclase
FJR03_RS05085	COG0784	Response regulator, receiver
FJR03_RS05085	COG2205	protein histidine kinase activity
FJR03_RS05090	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FJR03_RS05100	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FJR03_RS05100	COG2199	diguanylate cyclase activity
FJR03_RS05110	COG0784	Response regulator, receiver
FJR03_RS05110	COG2198	Histidine kinase
FJR03_RS05110	COG5002	protein histidine kinase activity
FJR03_RS05135	COG1609	Transcriptional regulator
FJR03_RS05140	COG3706	GGDEF domain
FJR03_RS05185	COG0784	Response regulator, receiver
FJR03_RS05185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FJR03_RS05185	COG2198	Histidine kinase
FJR03_RS05185	COG2205	protein histidine kinase activity
FJR03_RS05215	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FJR03_RS05225	COG0822	iron-sulfur transferase activity
FJR03_RS05230	COG0101	tRNA pseudouridine synthase activity
FJR03_RS05245	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FJR03_RS05250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FJR03_RS05255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FJR03_RS05260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FJR03_RS05270	COG1338	Plays a role in the flagellum-specific transport system
FJR03_RS05275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FJR03_RS05290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FJR03_RS05300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJR03_RS05305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FJR03_RS05315	COG0521	Mo-molybdopterin cofactor biosynthetic process
FJR03_RS05355	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FJR03_RS05370	COG0708	Exodeoxyribonuclease III
FJR03_RS05375	COG2048	Heterodisulfide reductase, subunit B
FJR03_RS05385	COG1053	succinate dehydrogenase
FJR03_RS05395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FJR03_RS05400	COG0585	pseudouridine synthase activity
FJR03_RS05415	COG0428	transporter
FJR03_RS05430	COG0012	GTP binding
FJR03_RS05440	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FJR03_RS05440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FJR03_RS05445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FJR03_RS05445	COG0574	Belongs to the PEP-utilizing enzyme family
FJR03_RS05450	COG1858	cytochrome C peroxidase
FJR03_RS05465	COG5001	Diguanylate cyclase
FJR03_RS05465	COG3300	MHYT domain
FJR03_RS05475	COG0659	secondary active sulfate transmembrane transporter activity
FJR03_RS05485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FJR03_RS05495	COG0133	tryptophan synthase activity
FJR03_RS05500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FJR03_RS05510	COG0698	ribose 5-phosphate isomerase
FJR03_RS05515	COG1994	Peptidase M50
FJR03_RS05520	COG0681	Belongs to the peptidase S26 family
FJR03_RS05525	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FJR03_RS05545	COG0674	pyruvate-flavodoxin oxidoreductase activity
FJR03_RS05545	COG1013	pyruvate-flavodoxin oxidoreductase activity
FJR03_RS05545	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FJR03_RS05545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FJR03_RS05550	COG2066	Belongs to the glutaminase family
FJR03_RS05560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FJR03_RS05575	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FJR03_RS05585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FJR03_RS05590	COG4786	Flagellar basal body rod
FJR03_RS05595	COG4786	Flagellar basal body rod
FJR03_RS05600	COG0066	3-isopropylmalate dehydratase activity
FJR03_RS05605	COG0473	3-isopropylmalate dehydrogenase activity
FJR03_RS05620	COG0788	formyltetrahydrofolate deformylase activity
FJR03_RS05645	COG2171	N-acyltransferase activity
FJR03_RS05670	COG1058	Belongs to the CinA family
FJR03_RS05670	COG1546	Belongs to the CinA family
FJR03_RS05675	COG3647	Membrane
FJR03_RS05685	COG0563	adenylate kinase activity
FJR03_RS05700	COG0563	adenylate kinase activity
FJR03_RS05705	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FJR03_RS05710	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FJR03_RS05730	COG0497	DNA recombination
FJR03_RS05735	COG0084	hydrolase, TatD family'
FJR03_RS05745	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FJR03_RS05750	COG0131	Imidazoleglycerol-phosphate dehydratase
FJR03_RS05755	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FJR03_RS05770	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FJR03_RS05790	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FJR03_RS05800	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FJR03_RS05815	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FJR03_RS05825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJR03_RS05825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJR03_RS05835	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FJR03_RS05855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FJR03_RS05875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FJR03_RS05895	COG2132	Multicopper oxidase
FJR03_RS05905	COG2217	Heavy metal translocating P-type atpase
FJR03_RS05935	COG1013	pyruvate-flavodoxin oxidoreductase activity
FJR03_RS05940	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FJR03_RS05940	COG0674	pyruvate-flavodoxin oxidoreductase activity
FJR03_RS05950	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FJR03_RS05955	COG0045	succinate-CoA ligase (ADP-forming) activity
FJR03_RS05960	COG0114	fumarate hydratase activity
FJR03_RS05965	COG0039	L-malate dehydrogenase activity
FJR03_RS05975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FJR03_RS05985	COG4591	ABC-type transport system involved in lipoprotein release permease component
FJR03_RS05990	COG0653	protein targeting
FJR03_RS05995	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FJR03_RS06000	COG1049	propionate catabolic process, 2-methylcitrate cycle
FJR03_RS06015	COG1196	nuclear chromosome segregation
FJR03_RS06015	COG1674	ftsk spoiiie
FJR03_RS06030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FJR03_RS06035	COG2183	response to ionizing radiation
FJR03_RS06045	COG3001	Fructosamine kinase
FJR03_RS06055	COG0095	Lipoate-protein ligase
FJR03_RS06060	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FJR03_RS06070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJR03_RS06080	COG0508	dehydrogenase complex catalyzes the overall conversion of
FJR03_RS06080	COG0022	dehydrogenase e1 component
FJR03_RS06085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FJR03_RS06090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FJR03_RS06095	COG0840	transmembrane signaling receptor activity
FJR03_RS06115	COG0163	prenyltransferase activity
FJR03_RS06120	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FJR03_RS06125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FJR03_RS06130	COG0124	histidyl-tRNA synthetase
FJR03_RS06140	COG1045	serine acetyltransferase
FJR03_RS06145	COG2193	ferroxidase activity
FJR03_RS06175	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FJR03_RS06180	COG0440	acetolactate synthase activity
FJR03_RS06185	COG0028	Belongs to the TPP enzyme family
FJR03_RS06195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FJR03_RS06205	COG0375	protein maturation
FJR03_RS06210	COG0309	Hydrogenase expression formation protein (HypE)
FJR03_RS06215	COG0409	Hydrogenase expression formation protein
FJR03_RS06220	COG0298	carbon dioxide binding
FJR03_RS06225	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FJR03_RS06245	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FJR03_RS06250	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FJR03_RS06260	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FJR03_RS06280	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FJR03_RS06285	COG1137	ATPase activity
FJR03_RS06290	COG0802	atpase or kinase
FJR03_RS06295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FJR03_RS06305	COG0640	Transcriptional regulator
FJR03_RS06310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FJR03_RS06340	COG3706	GGDEF domain
FJR03_RS06340	COG4251	negative regulation of phosphorylation
FJR03_RS06340	COG5001	Diguanylate cyclase
FJR03_RS06340	COG2203	Gaf domain
FJR03_RS06350	COG1408	metallophosphoesterase
FJR03_RS06375	COG1309	transcriptional regulator
FJR03_RS06385	COG1064	alcohol dehydrogenase
FJR03_RS06400	COG4895	conserved protein (DUF2196)
FJR03_RS06450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FJR03_RS06455	COG1028	Short-chain dehydrogenase reductase Sdr
FJR03_RS06460	COG1846	Transcriptional regulator
FJR03_RS06465	COG2207	Transcriptional regulator
FJR03_RS06470	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FJR03_RS06485	COG1032	radical SAM domain protein
FJR03_RS06495	COG0318	PFAM AMP-dependent synthetase and ligase
FJR03_RS06500	COG3706	GGDEF domain
FJR03_RS06505	COG1227	inorganic diphosphatase activity
FJR03_RS06510	COG2205	protein histidine kinase activity
FJR03_RS06510	COG4999	Histidine kinase
FJR03_RS06510	COG3850	Histidine kinase
FJR03_RS06510	COG3437	response regulator, receiver
FJR03_RS06520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FJR03_RS06525	COG0730	response to heat
FJR03_RS06535	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FJR03_RS06535	COG1776	CheC inhibitor of MCP methylation
FJR03_RS06550	COG1215	transferase activity, transferring glycosyl groups
FJR03_RS06555	COG2379	hydroxypyruvate reductase
FJR03_RS06560	COG3769	mannosylglycerate metabolic process
FJR03_RS06570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FJR03_RS06585	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FJR03_RS06595	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FJR03_RS06600	COG0493	'glutamate synthase
FJR03_RS06605	COG0067	glutamate synthase
FJR03_RS06605	COG0069	glutamate synthase activity
FJR03_RS06605	COG0070	glutamate synthase
FJR03_RS06650	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FJR03_RS06655	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FJR03_RS06670	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FJR03_RS06675	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FJR03_RS06740	COG1086	Polysaccharide biosynthesis protein
FJR03_RS06745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FJR03_RS06755	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FJR03_RS06760	COG0438	transferase activity, transferring glycosyl groups
FJR03_RS06765	COG0463	Glycosyl transferase, family 2
FJR03_RS06765	COG1216	Glycosyl transferase, family 2
FJR03_RS06770	COG1216	Glycosyl transferase, family 2
FJR03_RS06815	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FJR03_RS06820	COG1051	belongs to the nudix hydrolase family
FJR03_RS06825	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FJR03_RS06825	COG0662	Cupin 2, conserved barrel domain protein
FJR03_RS06830	COG1793	dna ligase
FJR03_RS06875	COG1845	cytochrome c oxidase, subunit III
FJR03_RS06880	COG0714	Associated with various cellular activities
FJR03_RS06890	COG3256	nitric oxide reductase
FJR03_RS06895	COG2010	Cytochrome c
FJR03_RS06910	COG1959	2 iron, 2 sulfur cluster binding
FJR03_RS06930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJR03_RS06950	COG0745	RESPONSE REGULATOR receiver
FJR03_RS06960	COG3328	transposase activity
FJR03_RS06970	COG1971	Probably functions as a manganese efflux pump
FJR03_RS06980	COG0531	amino acid
FJR03_RS06985	COG3706	GGDEF domain
FJR03_RS07020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FJR03_RS07025	COG0596	Alpha beta hydrolase
FJR03_RS07030	COG1181	Belongs to the D-alanine--D-alanine ligase family
FJR03_RS07035	COG0632	four-way junction helicase activity
FJR03_RS07045	COG0728	peptidoglycan biosynthetic process
FJR03_RS07050	COG0215	cysteine-tRNA ligase activity
FJR03_RS07055	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FJR03_RS07080	COG0167	dihydroorotate dehydrogenase activity
FJR03_RS07085	COG0612	Peptidase, M16
FJR03_RS07090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FJR03_RS07095	COG1028	Short-chain dehydrogenase reductase Sdr
FJR03_RS07110	COG3746	phosphate-selective porin O and P
FJR03_RS07125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FJR03_RS07130	COG0750	zinc metalloprotease
FJR03_RS07135	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FJR03_RS07145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJR03_RS07155	COG1629	transport
FJR03_RS07160	COG3338	carbonate dehydratase activity
FJR03_RS07170	COG2081	HI0933 family
FJR03_RS07185	COG0352	thiamine-phosphate diphosphorylase activity
FJR03_RS07205	COG5001	Diguanylate cyclase
FJR03_RS07205	COG3300	MHYT domain
FJR03_RS07230	COG0513	Belongs to the DEAD box helicase family
FJR03_RS07240	COG4974	Belongs to the 'phage' integrase family
FJR03_RS07255	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FJR03_RS07260	COG1393	Belongs to the ArsC family
FJR03_RS07270	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FJR03_RS07290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FJR03_RS07305	COG0784	Response regulator, receiver
FJR03_RS07305	COG0835	chemotaxis
FJR03_RS07315	COG0511	ligase activity, forming carbon-carbon bonds
FJR03_RS07315	COG5016	pyruvate
FJR03_RS07345	COG0326	Molecular chaperone. Has ATPase activity
FJR03_RS07355	COG2354	Protein conserved in bacteria
FJR03_RS07360	COG0488	(ABC) transporter
FJR03_RS07365	COG0471	metal ion transport
FJR03_RS07370	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FJR03_RS07375	COG3706	GGDEF domain
FJR03_RS07390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FJR03_RS07410	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FJR03_RS07425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FJR03_RS07430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FJR03_RS07440	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FJR03_RS07450	COG0484	heat shock protein binding
FJR03_RS07460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FJR03_RS07470	COG0849	cell division
FJR03_RS07480	COG0484	heat shock protein binding
FJR03_RS07490	COG1136	(ABC) transporter
FJR03_RS07510	COG2890	protein-(glutamine-N5) methyltransferase activity
FJR03_RS07515	COG0501	Belongs to the peptidase M48B family
FJR03_RS07530	COG0471	metal ion transport
FJR03_RS07540	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FJR03_RS07550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FJR03_RS07555	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FJR03_RS07560	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FJR03_RS07575	COG0356	it plays a direct role in the translocation of protons across the membrane
FJR03_RS07585	COG1418	mRNA catabolic process
FJR03_RS07600	COG0552	protein localization to endoplasmic reticulum
FJR03_RS07605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FJR03_RS07615	COG0288	reversible hydration of carbon dioxide
FJR03_RS07620	COG1580	Controls the rotational direction of flagella during chemotaxis
FJR03_RS07625	COG0840	transmembrane signaling receptor activity
FJR03_RS07635	COG0736	holo-[acyl-carrier-protein] synthase activity
FJR03_RS07645	COG2863	cytochrome
FJR03_RS07655	COG0436	Aminotransferase
FJR03_RS07675	COG1193	negative regulation of DNA recombination
FJR03_RS07680	COG2081	HI0933 family
FJR03_RS07685	COG1704	LemA family
FJR03_RS07705	COG5001	Diguanylate cyclase
FJR03_RS07705	COG4251	negative regulation of phosphorylation
FJR03_RS07705	COG3706	GGDEF domain
FJR03_RS07705	COG2203	Gaf domain
FJR03_RS07710	COG0525	valine-tRNA ligase activity
FJR03_RS07715	COG3447	MASE1 domain protein
FJR03_RS07715	COG5001	Diguanylate cyclase
FJR03_RS07715	COG5002	protein histidine kinase activity
FJR03_RS07720	COG0659	secondary active sulfate transmembrane transporter activity
FJR03_RS07725	COG2200	EAL domain
FJR03_RS07725	COG2199	diguanylate cyclase activity
FJR03_RS07740	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FJR03_RS07745	COG1610	YqeY-like protein
FJR03_RS07750	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FJR03_RS07785	COG0482	sulfurtransferase activity
FJR03_RS07790	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FJR03_RS07790	COG1776	CheC inhibitor of MCP methylation
FJR03_RS07795	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FJR03_RS07800	COG1191	sigma factor activity
FJR03_RS07810	COG0455	bacterial-type flagellum organization
FJR03_RS07820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FJR03_RS07825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FJR03_RS07835	COG0402	S-adenosylhomocysteine deaminase activity
FJR03_RS07840	COG0616	signal peptide processing
FJR03_RS07845	COG1570	exodeoxyribonuclease VII activity
FJR03_RS07855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJR03_RS07855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJR03_RS07860	COG0779	Required for maturation of 30S ribosomal subunits
FJR03_RS07870	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FJR03_RS07880	COG0083	homoserine kinase activity
FJR03_RS07890	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FJR03_RS07905	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FJR03_RS07910	COG0157	Belongs to the NadC ModD family
FJR03_RS07920	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FJR03_RS07930	COG0745	RESPONSE REGULATOR receiver
FJR03_RS07935	COG0642	Histidine kinase
FJR03_RS07940	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FJR03_RS07950	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJR03_RS07955	COG0287	Prephenate dehydrogenase
FJR03_RS07965	COG2304	oxidoreductase activity
FJR03_RS07985	COG0714	Associated with various cellular activities
FJR03_RS08035	COG0004	ammonium transporteR
FJR03_RS08045	COG0004	ammonium transporteR
FJR03_RS08065	COG2204	response regulator
FJR03_RS08070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FJR03_RS08080	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FJR03_RS08085	COG0731	radical SAM domain protein
FJR03_RS08125	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FJR03_RS08130	COG0459	protein refolding
FJR03_RS08140	COG0519	Catalyzes the synthesis of GMP from XMP
FJR03_RS08145	COG3706	GGDEF domain
FJR03_RS08170	COG0848	biopolymer transport protein
FJR03_RS08175	COG0811	peptide transport
FJR03_RS08180	COG3850	Histidine kinase
FJR03_RS08180	COG5002	protein histidine kinase activity
FJR03_RS08185	COG0745	RESPONSE REGULATOR receiver
FJR03_RS08190	COG0418	dihydroorotase activity
FJR03_RS08200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FJR03_RS08250	COG1459	type II secretion system
FJR03_RS08270	COG3920	Histidine kinase
FJR03_RS08275	COG0745	RESPONSE REGULATOR receiver
FJR03_RS08280	COG1278	Cold shock
FJR03_RS08285	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FJR03_RS08290	COG0280	phosphate acetyltransferase
FJR03_RS08290	COG0857	belongs to the CobB CobQ family
FJR03_RS08295	COG3012	SEC-C Motif Domain Protein
FJR03_RS08310	COG0488	(ABC) transporter
FJR03_RS08325	COG1283	sodium-dependent phosphate transmembrane transporter activity
FJR03_RS08330	COG5001	Diguanylate cyclase
FJR03_RS08330	COG4251	negative regulation of phosphorylation
FJR03_RS08330	COG3706	GGDEF domain
FJR03_RS08330	COG2203	Gaf domain
FJR03_RS08345	COG0006	proline dipeptidase activity
FJR03_RS08360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FJR03_RS08365	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FJR03_RS08370	COG0835	chemotaxis
FJR03_RS08375	COG0784	Response regulator, receiver
FJR03_RS08375	COG2198	Histidine kinase
FJR03_RS08375	COG0643	Histidine kinase
FJR03_RS08380	COG0784	Response regulator, receiver
FJR03_RS08380	COG0835	chemotaxis
FJR03_RS08390	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FJR03_RS08415	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FJR03_RS08425	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FJR03_RS08435	COG4206	TonB-dependent receptor
FJR03_RS08440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FJR03_RS08445	COG1120	ATPase activity
FJR03_RS08465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FJR03_RS08470	COG4772	TonB-dependent receptor
FJR03_RS08485	COG0500	methyltransferase
FJR03_RS08495	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FJR03_RS08500	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FJR03_RS08505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FJR03_RS08510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FJR03_RS08525	COG1692	metallophosphoesterase
FJR03_RS08530	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FJR03_RS08540	COG0739	heme binding
FJR03_RS08545	COG0285	dihydrofolate synthase activity
FJR03_RS08560	COG0495	leucyl-tRNA aminoacylation
FJR03_RS08570	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FJR03_RS08575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FJR03_RS08580	COG1862	Preprotein translocase
FJR03_RS08585	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FJR03_RS08595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FJR03_RS08600	COG0659	secondary active sulfate transmembrane transporter activity
FJR03_RS08605	COG0288	reversible hydration of carbon dioxide
FJR03_RS08625	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FJR03_RS08630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FJR03_RS08635	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FJR03_RS08650	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FJR03_RS08655	COG0135	phosphoribosylanthranilate isomerase activity
FJR03_RS08665	COG0825	malonyl-CoA metabolic process
FJR03_RS08670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJR03_RS08675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJR03_RS08685	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FJR03_RS08690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FJR03_RS08695	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FJR03_RS08700	COG2860	membrane
FJR03_RS08725	COG0582	viral genome integration into host DNA
FJR03_RS08805	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FJR03_RS08810	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FJR03_RS08830	COG1131	(ABC) transporter
FJR03_RS08835	COG0842	Transport permease protein
FJR03_RS08840	COG0842	Transport permease protein
FJR03_RS08850	COG1194	a g-specific adenine glycosylase
FJR03_RS08865	COG3706	GGDEF domain
FJR03_RS08880	COG2067	long-chain fatty acid transport protein
FJR03_RS08895	COG0842	Transport permease protein
FJR03_RS08900	COG0842	Transport permease protein
FJR03_RS08900	COG1129	ABC transporter
FJR03_RS08905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJR03_RS08930	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FJR03_RS08940	COG0556	nucleotide-excision repair
FJR03_RS08960	COG2199	diguanylate cyclase activity
FJR03_RS08960	COG2203	Gaf domain
FJR03_RS08975	COG2861	carbohydrate metabolic process
FJR03_RS08980	COG0360	Binds together with S18 to 16S ribosomal RNA
FJR03_RS08985	COG0629	single-stranded DNA binding
FJR03_RS08990	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FJR03_RS09005	COG0560	Phosphoserine phosphatase
FJR03_RS09015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FJR03_RS09030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FJR03_RS09035	COG2264	protein methyltransferase activity
FJR03_RS09040	COG0745	RESPONSE REGULATOR receiver
FJR03_RS09045	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FJR03_RS09050	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FJR03_RS09070	COG0628	permease
FJR03_RS09075	COG2255	four-way junction helicase activity
FJR03_RS09080	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FJR03_RS09090	COG0159	tryptophan synthase activity
FJR03_RS09125	COG2873	o-acetylhomoserine
FJR03_RS09130	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FJR03_RS09135	COG0542	response to heat
FJR03_RS09140	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FJR03_RS09170	COG0335	large ribosomal subunit rRNA binding
FJR03_RS09175	COG0336	Belongs to the RNA methyltransferase TrmD family
FJR03_RS09180	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FJR03_RS09190	COG0228	four-way junction DNA binding
FJR03_RS09195	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FJR03_RS09200	COG1451	nucleotide metabolic process
FJR03_RS09205	COG1671	Belongs to the UPF0178 family
FJR03_RS09215	COG0564	pseudouridine synthase activity
FJR03_RS09220	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FJR03_RS09220	COG1519	Transferase
FJR03_RS09230	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FJR03_RS09235	COG3063	Type IV pilus biogenesis stability protein PilW
FJR03_RS09240	COG0739	heme binding
FJR03_RS09245	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FJR03_RS09250	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FJR03_RS09255	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FJR03_RS09260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FJR03_RS09265	COG0210	DNA helicase
FJR03_RS09280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FJR03_RS09290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FJR03_RS09305	COG0784	Response regulator, receiver
FJR03_RS09305	COG3437	response regulator, receiver
FJR03_RS09315	COG5001	Diguanylate cyclase
FJR03_RS09315	COG5002	protein histidine kinase activity
FJR03_RS09320	COG1342	Belongs to the UPF0251 family
FJR03_RS09330	COG1271	oxidase subunit
FJR03_RS09355	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FJR03_RS09360	COG0784	Response regulator, receiver
FJR03_RS09360	COG3437	response regulator, receiver
FJR03_RS09365	COG1185	polyribonucleotide nucleotidyltransferase activity
FJR03_RS09375	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FJR03_RS09395	COG0519	Catalyzes the synthesis of GMP from XMP
FJR03_RS09395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FJR03_RS09415	COG0322	excinuclease ABC activity
FJR03_RS09420	COG0840	transmembrane signaling receptor activity
FJR03_RS09430	COG2205	protein histidine kinase activity
FJR03_RS09430	COG5002	protein histidine kinase activity
FJR03_RS09430	COG0784	Response regulator, receiver
FJR03_RS09435	COG0784	Response regulator, receiver
FJR03_RS09440	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FJR03_RS09445	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJR03_RS09470	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FJR03_RS09475	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FJR03_RS09480	COG0752	glycyl-tRNA synthetase alpha subunit
FJR03_RS09500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FJR03_RS09510	COG0826	peptidase U32
FJR03_RS09520	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FJR03_RS09530	COG3118	belongs to the thioredoxin family
FJR03_RS09540	COG0492	ferredoxin-NADP+ reductase activity
FJR03_RS09545	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FJR03_RS09555	COG1007	ATP synthesis coupled electron transport
FJR03_RS09565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FJR03_RS09570	COG0713	ATP synthesis coupled electron transport
FJR03_RS09575	COG0839	Belongs to the complex I subunit 6 family
FJR03_RS09580	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR03_RS09585	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FJR03_RS09590	COG1034	ATP synthesis coupled electron transport
FJR03_RS09610	COG0649	NAD binding
FJR03_RS09615	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR03_RS09620	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR03_RS09625	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR03_RS09635	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FJR03_RS09650	COG1222	aaa ATPase
FJR03_RS09660	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FJR03_RS09670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FJR03_RS09680	COG0484	heat shock protein binding
FJR03_RS09685	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FJR03_RS09690	COG1242	4 iron, 4 sulfur cluster binding
FJR03_RS09705	COG0745	RESPONSE REGULATOR receiver
FJR03_RS09720	COG0140	phosphoribosyl-ATP diphosphatase activity
FJR03_RS09720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FJR03_RS09745	COG0811	peptide transport
FJR03_RS09755	COG0848	biopolymer transport protein
FJR03_RS09775	COG0745	RESPONSE REGULATOR receiver
FJR03_RS09795	COG0581	inorganic phosphate transmembrane transporter activity
FJR03_RS09800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FJR03_RS09805	COG0704	Plays a role in the regulation of phosphate uptake
FJR03_RS09810	COG2205	protein histidine kinase activity
FJR03_RS09825	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FJR03_RS09830	COG0174	glutamine synthetase
FJR03_RS09835	COG2205	protein histidine kinase activity
FJR03_RS09835	COG0784	Response regulator, receiver
FJR03_RS09835	COG2198	Histidine kinase
FJR03_RS09845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FJR03_RS09855	COG0577	efflux transmembrane transporter activity
FJR03_RS09855	COG1136	(ABC) transporter
FJR03_RS09880	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FJR03_RS09885	COG0444	Belongs to the ABC transporter superfamily
FJR03_RS09890	COG0156	8-amino-7-oxononanoate synthase activity
FJR03_RS09900	COG0424	maF-like protein
FJR03_RS09910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FJR03_RS09925	COG1012	belongs to the aldehyde dehydrogenase family
FJR03_RS09935	COG0792	nuclease activity
FJR03_RS09945	COG3383	formate dehydrogenase (NAD+) activity
FJR03_RS09960	COG0642	Histidine kinase
FJR03_RS09980	COG3258	Cytochrome c
FJR03_RS09985	COG0737	Belongs to the 5'-nucleotidase family
FJR03_RS10010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FJR03_RS10030	COG0460	homoserine dehydrogenase
FJR03_RS10035	COG0436	Aminotransferase
FJR03_RS10050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FJR03_RS10055	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FJR03_RS10060	COG0254	rRNA binding
FJR03_RS10080	COG0602	queuosine metabolic process
FJR03_RS10085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FJR03_RS10100	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FJR03_RS10105	COG0723	plastoquinol--plastocyanin reductase activity
FJR03_RS10135	COG5002	protein histidine kinase activity
FJR03_RS10140	COG4269	membrane
FJR03_RS10145	COG0501	Belongs to the peptidase M48B family
FJR03_RS10150	COG3150	esterase
FJR03_RS10165	COG1881	PFAM PEBP family protein
FJR03_RS10170	COG2020	methyltransferase activity
FJR03_RS10190	COG0456	acetyltransferase
FJR03_RS10200	COG0667	Aldo Keto reductase
FJR03_RS10210	COG4221	oxidoreductase activity
FJR03_RS10220	COG0179	Fumarylacetoacetate (FAA) hydrolase
FJR03_RS10230	COG0840	transmembrane signaling receptor activity
FJR03_RS10235	COG1366	Belongs to the anti-sigma-factor antagonist family
FJR03_RS10240	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FJR03_RS10245	COG0840	transmembrane signaling receptor activity
FJR03_RS10260	COG0445	tRNA wobble uridine modification
FJR03_RS10280	COG0514	ATP-dependent DNA helicase (RecQ)
FJR03_RS10300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FJR03_RS10310	COG2203	Gaf domain
FJR03_RS10310	COG2199	diguanylate cyclase activity
FJR03_RS10325	COG1854	S-ribosylhomocysteine lyase activity
FJR03_RS10330	COG1355	regulation of microtubule-based process
FJR03_RS10340	COG3885	ferrous iron binding
FJR03_RS10340	COG2078	PFAM AMMECR1 domain protein
FJR03_RS10345	COG1013	pyruvate-flavodoxin oxidoreductase activity
FJR03_RS10350	COG0674	pyruvate-flavodoxin oxidoreductase activity
FJR03_RS10355	COG1144	Oxidoreductase
FJR03_RS10360	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FJR03_RS10365	COG0546	phosphoglycolate phosphatase activity
FJR03_RS10380	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FJR03_RS10385	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FJR03_RS10410	COG1074	ATP-dependent DNA helicase activity
FJR03_RS10450	COG3278	Belongs to the heme-copper respiratory oxidase family
FJR03_RS10455	COG0505	Belongs to the CarA family
FJR03_RS10475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FJR03_RS10480	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FJR03_RS10485	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FJR03_RS10490	COG1968	undecaprenyl-diphosphatase activity
FJR03_RS10495	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FJR03_RS10500	COG2814	Major facilitator Superfamily
FJR03_RS10515	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FJR03_RS10525	COG0129	dihydroxy-acid dehydratase activity
FJR03_RS10555	COG0582	viral genome integration into host DNA
FJR03_RS10595	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FJR03_RS10620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FJR03_RS10625	COG1047	Peptidyl-prolyl cis-trans
FJR03_RS10685	COG0577	efflux transmembrane transporter activity
FJR03_RS10685	COG1136	(ABC) transporter
FJR03_RS10690	COG0577	efflux transmembrane transporter activity
FJR03_RS10690	COG1136	(ABC) transporter
FJR03_RS10725	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FJR03_RS10740	COG1858	cytochrome C peroxidase
FJR03_RS10775	COG3706	GGDEF domain
FJR03_RS10780	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FJR03_RS10785	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FJR03_RS10800	COG0840	transmembrane signaling receptor activity
FJR03_RS10825	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FJR03_RS10855	COG1393	Belongs to the ArsC family
FJR03_RS10860	COG0492	ferredoxin-NADP+ reductase activity
FJR03_RS10865	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJR03_RS10865	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJR03_RS10875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FJR03_RS10885	COG1450	Type ii and iii secretion system protein
FJR03_RS10910	COG4962	Type ii secretion system protein e
FJR03_RS10950	COG0069	glutamate synthase activity
FJR03_RS10955	COG2259	Doxx family
FJR03_RS10975	COG2201	protein-glutamate methylesterase activity
FJR03_RS10980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FJR03_RS10990	COG0513	Belongs to the DEAD box helicase family
FJR03_RS10995	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FJR03_RS11000	COG0745	RESPONSE REGULATOR receiver
FJR03_RS11005	COG0642	Histidine kinase
FJR03_RS11010	COG2301	Belongs to the HpcH HpaI aldolase family
FJR03_RS11030	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FJR03_RS11035	COG2885	chlorophyll binding
FJR03_RS11040	COG0746	molybdenum cofactor guanylyltransferase activity
FJR03_RS11045	COG0315	cyclic pyranopterin monophosphate synthase activity
FJR03_RS11070	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FJR03_RS11105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FJR03_RS11110	COG0571	ribonuclease III activity
FJR03_RS11115	COG0328	RNA-DNA hybrid ribonuclease activity
FJR03_RS11130	COG2855	membrane
FJR03_RS11140	COG0348	domain, Protein
FJR03_RS11160	COG1410	methionine synthase
FJR03_RS11160	COG0646	methionine synthase
FJR03_RS11165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FJR03_RS11175	COG0606	chelatase, subunit chli
FJR03_RS11185	COG0242	peptide deformylase activity
FJR03_RS11195	COG0740	serine-type endopeptidase activity
FJR03_RS11200	COG0544	peptidyl-prolyl cis-trans isomerase activity
FJR03_RS11205	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FJR03_RS11210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FJR03_RS11215	COG0268	Binds directly to 16S ribosomal RNA
FJR03_RS11220	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FJR03_RS11225	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FJR03_RS11230	COG0237	dephospho-CoA kinase activity
FJR03_RS11235	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FJR03_RS11245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FJR03_RS11250	COG2067	long-chain fatty acid transport protein
FJR03_RS11275	COG0670	Belongs to the BI1 family
FJR03_RS11280	COG0352	thiamine-phosphate diphosphorylase activity
FJR03_RS11290	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FJR03_RS11295	COG1121	(ABC) transporter
FJR03_RS11300	COG0803	Belongs to the bacterial solute-binding protein 9 family
FJR03_RS11305	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FJR03_RS11310	COG0297	glycogen (starch) synthase activity
FJR03_RS11315	COG1940	carbohydrate kinase activity
FJR03_RS11320	COG0297	glycogen (starch) synthase activity
FJR03_RS11330	COG1449	Belongs to the glycosyl hydrolase 57 family
FJR03_RS11340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FJR03_RS11350	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FJR03_RS11355	COG0233	cytoplasmic translational termination
FJR03_RS11360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FJR03_RS11370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FJR03_RS11370	COG0475	glutathione-regulated potassium exporter activity
FJR03_RS11375	COG0504	CTP synthase activity
FJR03_RS11380	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FJR03_RS11380	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FJR03_RS11385	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FJR03_RS11395	COG1157	protein secretion by the type III secretion system
FJR03_RS11405	COG1730	sister chromatid segregation
FJR03_RS11425	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FJR03_RS11430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FJR03_RS11440	COG0107	imidazoleglycerol-phosphate synthase activity
FJR03_RS11445	COG0778	Nitroreductase
FJR03_RS11455	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FJR03_RS11465	COG0564	pseudouridine synthase activity
FJR03_RS11470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FJR03_RS11475	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FJR03_RS11485	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FJR03_RS11490	COG3118	belongs to the thioredoxin family
FJR03_RS11495	COG3123	guanosine phosphorylase activity
FJR03_RS11500	COG0531	amino acid
FJR03_RS11505	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FJR03_RS11535	COG3437	response regulator, receiver
FJR03_RS11535	COG0784	Response regulator, receiver
FJR03_RS11560	COG0840	transmembrane signaling receptor activity
FJR03_RS11600	COG3604	Transcriptional regulator
FJR03_RS11615	COG0840	transmembrane signaling receptor activity
FJR03_RS11640	COG0508	dehydrogenase complex catalyzes the overall conversion of
FJR03_RS11640	COG0022	dehydrogenase e1 component
FJR03_RS11670	COG2827	Endonuclease containing a URI domain
FJR03_RS11730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJR03_RS11755	COG0840	transmembrane signaling receptor activity
FJR03_RS11760	COG0840	transmembrane signaling receptor activity
FJR03_RS11775	COG2165	general secretion pathway protein