locus-tag	class	description
FM071_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FM071_RS00010	COG0592	DNA-directed DNA polymerase activity
FM071_RS00015	COG0187	DNA topoisomerase II activity
FM071_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FM071_RS00035	COG0617	tRNA 3'-terminal CCA addition
FM071_RS00040	COG1217	gtp-binding protein TYPA
FM071_RS00050	COG0429	hydrolase of the alpha beta-hydrolase fold
FM071_RS00055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FM071_RS00085	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FM071_RS00095	COG0840	transmembrane signaling receptor activity
FM071_RS00100	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FM071_RS00115	COG0640	Transcriptional regulator
FM071_RS00120	COG2010	Cytochrome c
FM071_RS00165	COG0745	RESPONSE REGULATOR receiver
FM071_RS00170	COG0642	Histidine kinase
FM071_RS00190	COG0358	DNA primase activity
FM071_RS00215	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FM071_RS00225	COG1749	Flagellar hook protein flgE
FM071_RS00230	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FM071_RS00235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FM071_RS00240	COG1238	metal cluster binding
FM071_RS00255	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FM071_RS00270	COG3287	FIST C domain
FM071_RS00270	COG2199	diguanylate cyclase activity
FM071_RS00270	COG2200	EAL domain
FM071_RS00275	COG1666	GTP binding
FM071_RS00285	COG0569	domain protein
FM071_RS00290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FM071_RS00295	COG0038	chloride channel
FM071_RS00300	COG0668	transmembrane transport
FM071_RS00320	COG0406	alpha-ribazole phosphatase activity
FM071_RS00375	COG0668	transmembrane transport
FM071_RS00395	COG0840	transmembrane signaling receptor activity
FM071_RS00405	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FM071_RS00410	COG1492	cobalamin metabolic process
FM071_RS00430	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FM071_RS00435	COG5001	Diguanylate cyclase
FM071_RS00435	COG5002	protein histidine kinase activity
FM071_RS00440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FM071_RS00445	COG1122	ATPase activity
FM071_RS00475	COG0575	Belongs to the CDS family
FM071_RS00480	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FM071_RS00485	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FM071_RS00490	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FM071_RS00515	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FM071_RS00520	COG0148	phosphopyruvate hydratase activity
FM071_RS00540	COG2239	Acts as a magnesium transporter
FM071_RS00545	COG1253	flavin adenine dinucleotide binding
FM071_RS00560	COG0367	asparagine synthase
FM071_RS00570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FM071_RS00575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FM071_RS00600	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FM071_RS00610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FM071_RS00630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FM071_RS00635	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FM071_RS00640	COG2089	acid synthase
FM071_RS00650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FM071_RS00660	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FM071_RS00695	COG1671	Belongs to the UPF0178 family
FM071_RS00725	COG0733	neurotransmitter:sodium symporter activity
FM071_RS00740	COG2022	thiamine diphosphate biosynthetic process
FM071_RS00745	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FM071_RS00745	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FM071_RS00755	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FM071_RS00755	COG0517	IMP dehydrogenase activity
FM071_RS00760	COG1187	pseudouridine synthase activity
FM071_RS00765	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FM071_RS00765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FM071_RS00775	COG0840	transmembrane signaling receptor activity
FM071_RS00785	COG0281	malic enzyme
FM071_RS00790	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FM071_RS00800	COG0314	molybdopterin synthase activity
FM071_RS00805	COG0303	'Molybdopterin
FM071_RS00860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FM071_RS00870	COG0051	transcription antitermination factor activity, RNA binding
FM071_RS00875	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FM071_RS00880	COG0088	Forms part of the polypeptide exit tunnel
FM071_RS00885	COG0089	rRNA binding
FM071_RS00890	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FM071_RS00895	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FM071_RS00900	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FM071_RS00905	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FM071_RS00910	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FM071_RS00915	COG0255	Belongs to the universal ribosomal protein uL29 family
FM071_RS00920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FM071_RS00925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FM071_RS00930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FM071_RS00935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FM071_RS00940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FM071_RS00945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FM071_RS00950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FM071_RS00955	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FM071_RS00960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FM071_RS00965	COG0200	Binds to the 23S rRNA
FM071_RS00970	COG0201	protein transport
FM071_RS00975	COG0024	Methionine aminopeptidase
FM071_RS00980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FM071_RS01015	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FM071_RS01035	COG0071	Belongs to the small heat shock protein (HSP20) family
FM071_RS01040	COG0071	Belongs to the small heat shock protein (HSP20) family
FM071_RS01045	COG0071	Belongs to the small heat shock protein (HSP20) family
FM071_RS01060	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FM071_RS01065	COG0709	Synthesizes selenophosphate from selenide and ATP
FM071_RS01075	COG0778	Nitroreductase
FM071_RS01120	COG3706	GGDEF domain
FM071_RS01120	COG4251	negative regulation of phosphorylation
FM071_RS01120	COG2203	Gaf domain
FM071_RS01120	COG5001	Diguanylate cyclase
FM071_RS01125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FM071_RS01130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FM071_RS01135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FM071_RS01140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FM071_RS01145	COG0202	RNA polymerase activity
FM071_RS01150	COG0203	ribosomal protein L17
FM071_RS01170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FM071_RS01175	COG2267	carboxylic ester hydrolase activity
FM071_RS01190	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FM071_RS01195	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FM071_RS01205	COG0142	geranyltranstransferase activity
FM071_RS01210	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FM071_RS01230	COG0840	transmembrane signaling receptor activity
FM071_RS01230	COG5278	phosphoserine phosphatase activity
FM071_RS01235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FM071_RS01240	COG3022	response to hydroperoxide
FM071_RS01270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FM071_RS01275	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FM071_RS01290	COG0250	Participates in transcription elongation, termination and antitermination
FM071_RS01295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FM071_RS01300	COG0081	regulation of translation
FM071_RS01305	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FM071_RS01310	COG0222	ribosome binding
FM071_RS01315	COG0085	RNA polymerase activity
FM071_RS01320	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FM071_RS01325	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FM071_RS01330	COG0049	tRNA binding
FM071_RS01335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FM071_RS01345	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FM071_RS01355	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FM071_RS01360	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FM071_RS01375	COG1558	bacterial-type flagellum-dependent cell motility
FM071_RS01395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FM071_RS01405	COG0739	heme binding
FM071_RS01415	COG0277	FAD linked oxidase domain protein
FM071_RS01420	COG1295	ribonuclease BN
FM071_RS01430	COG0305	Participates in initiation and elongation during chromosome replication
FM071_RS01435	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FM071_RS01445	COG2957	Belongs to the agmatine deiminase family
FM071_RS01450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FM071_RS01455	COG2199	diguanylate cyclase activity
FM071_RS01455	COG2200	EAL domain
FM071_RS01455	COG3287	FIST C domain
FM071_RS01475	COG0357	Ribosomal RNA small subunit methyltransferase G
FM071_RS01485	COG0784	Response regulator, receiver
FM071_RS01485	COG4191	Histidine kinase
FM071_RS01495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FM071_RS01500	COG0113	porphobilinogen synthase activity
FM071_RS01505	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FM071_RS01530	COG1981	membrane
FM071_RS01535	COG1160	GTP binding
FM071_RS01545	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FM071_RS01555	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FM071_RS01570	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FM071_RS01575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FM071_RS01590	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FM071_RS01595	COG0612	Peptidase, M16
FM071_RS01600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FM071_RS01610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FM071_RS01625	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FM071_RS01635	COG2205	protein histidine kinase activity
FM071_RS01635	COG0784	Response regulator, receiver
FM071_RS01640	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FM071_RS01655	COG0772	Belongs to the SEDS family
FM071_RS01660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FM071_RS01665	COG0586	Pfam SNARE associated Golgi protein
FM071_RS01675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FM071_RS01685	COG0052	Belongs to the universal ribosomal protein uS2 family
FM071_RS01690	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FM071_RS01695	COG1136	(ABC) transporter
FM071_RS01710	COG0194	GDP metabolic process
FM071_RS01715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FM071_RS01720	COG0018	arginyl-trna synthetase
FM071_RS01735	COG1757	Na H antiporter
FM071_RS01740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FM071_RS01765	COG4948	Mandelate Racemase Muconate Lactonizing
FM071_RS01770	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FM071_RS01785	COG3864	Putative metallopeptidase domain
FM071_RS01795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FM071_RS01800	COG0697	spore germination
FM071_RS01805	COG3706	GGDEF domain
FM071_RS01815	COG0450	alkyl hydroperoxide reductase
FM071_RS01820	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FM071_RS01830	COG0105	UTP biosynthetic process
FM071_RS01840	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FM071_RS01845	COG0416	fatty acid biosynthetic process
FM071_RS01850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FM071_RS01860	COG0513	Belongs to the DEAD box helicase family
FM071_RS01865	COG1322	Protein conserved in bacteria
FM071_RS01885	COG1183	phosphatidylcholine synthase activity
FM071_RS01900	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FM071_RS01905	COG0745	RESPONSE REGULATOR receiver
FM071_RS01910	COG0642	Histidine kinase
FM071_RS01920	COG0799	negative regulation of ribosome biogenesis
FM071_RS01925	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FM071_RS01935	COG0126	phosphoglycerate kinase activity
FM071_RS01940	COG0149	triose-phosphate isomerase activity
FM071_RS01945	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FM071_RS01965	COG0195	Participates in both transcription termination and antitermination
FM071_RS01975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FM071_RS01980	COG2121	Domain of unknown function (DUF374)
FM071_RS01990	COG4974	Belongs to the 'phage' integrase family
FM071_RS02010	COG0037	tRNA processing
FM071_RS02015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FM071_RS02020	COG2081	HI0933 family
FM071_RS02030	COG0556	nucleotide-excision repair
FM071_RS02040	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FM071_RS02075	COG2860	membrane
FM071_RS02080	COG0788	formyltetrahydrofolate deformylase activity
FM071_RS02085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FM071_RS02090	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FM071_RS02100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FM071_RS02105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FM071_RS02110	COG0825	malonyl-CoA metabolic process
FM071_RS02115	COG2176	DNA-directed DNA polymerase activity
FM071_RS02120	COG0135	phosphoribosylanthranilate isomerase activity
FM071_RS02125	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FM071_RS02140	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FM071_RS02145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FM071_RS02150	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FM071_RS02160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FM071_RS02165	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FM071_RS02170	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FM071_RS02175	COG1862	Preprotein translocase
FM071_RS02180	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FM071_RS02185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FM071_RS02195	COG0495	leucyl-tRNA aminoacylation
FM071_RS02210	COG0285	dihydrofolate synthase activity
FM071_RS02215	COG0739	heme binding
FM071_RS02225	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FM071_RS02230	COG1692	metallophosphoesterase
FM071_RS02240	COG1538	Outer membrane efflux protein
FM071_RS02255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM071_RS02350	COG0745	RESPONSE REGULATOR receiver
FM071_RS02360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FM071_RS02365	COG1365	unkown
FM071_RS02370	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FM071_RS02380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FM071_RS02395	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FM071_RS02400	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FM071_RS02425	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FM071_RS02435	COG0835	chemotaxis
FM071_RS02435	COG0784	Response regulator, receiver
FM071_RS02440	COG2198	Histidine kinase
FM071_RS02440	COG0643	Histidine kinase
FM071_RS02440	COG0784	Response regulator, receiver
FM071_RS02445	COG0835	chemotaxis
FM071_RS02450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FM071_RS02460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FM071_RS02460	COG3008	intermembrane lipid transfer
FM071_RS02470	COG0006	proline dipeptidase activity
FM071_RS02485	COG2203	Gaf domain
FM071_RS02485	COG3706	GGDEF domain
FM071_RS02485	COG4251	negative regulation of phosphorylation
FM071_RS02485	COG5001	Diguanylate cyclase
FM071_RS02490	COG0023	Translation Initiation Factor
FM071_RS02500	COG0488	(ABC) transporter
FM071_RS02515	COG3012	SEC-C Motif Domain Protein
FM071_RS02530	COG0280	phosphate acetyltransferase
FM071_RS02530	COG0857	belongs to the CobB CobQ family
FM071_RS02535	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FM071_RS02540	COG1278	Cold shock
FM071_RS02555	COG0418	dihydroorotase activity
FM071_RS02570	COG0811	peptide transport
FM071_RS02575	COG0848	biopolymer transport protein
FM071_RS02590	COG0459	protein refolding
FM071_RS02595	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FM071_RS02620	COG1309	transcriptional regulator
FM071_RS02645	COG0842	Transport permease protein
FM071_RS02645	COG1129	ABC transporter
FM071_RS02650	COG0842	Transport permease protein
FM071_RS02655	COG0842	Transport permease protein
FM071_RS02660	COG0731	radical SAM domain protein
FM071_RS02665	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FM071_RS02675	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FM071_RS02680	COG2204	response regulator
FM071_RS02700	COG0004	ammonium transporteR
FM071_RS02710	COG0004	ammonium transporteR
FM071_RS02715	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FM071_RS02750	COG0714	Associated with various cellular activities
FM071_RS02770	COG2304	oxidoreductase activity
FM071_RS02780	COG0287	Prephenate dehydrogenase
FM071_RS02785	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FM071_RS02805	COG0745	RESPONSE REGULATOR receiver
FM071_RS02815	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FM071_RS02825	COG0157	Belongs to the NadC ModD family
FM071_RS02830	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FM071_RS02845	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FM071_RS02855	COG0083	homoserine kinase activity
FM071_RS02860	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FM071_RS02870	COG0779	Required for maturation of 30S ribosomal subunits
FM071_RS02875	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FM071_RS02875	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FM071_RS02885	COG1570	exodeoxyribonuclease VII activity
FM071_RS02895	COG0616	signal peptide processing
FM071_RS02900	COG0402	S-adenosylhomocysteine deaminase activity
FM071_RS02905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FM071_RS02910	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FM071_RS02915	COG1419	protein localization to endoplasmic reticulum
FM071_RS02920	COG0455	bacterial-type flagellum organization
FM071_RS02930	COG1191	sigma factor activity
FM071_RS02940	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FM071_RS02945	COG0482	sulfurtransferase activity
FM071_RS02970	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FM071_RS02980	COG0339	signal peptide processing
FM071_RS02990	COG0243	molybdopterin cofactor binding
FM071_RS02995	COG0437	4 iron, 4 sulfur cluster binding
FM071_RS03000	COG0348	domain, Protein
FM071_RS03005	COG3043	anaerobic respiration
FM071_RS03020	COG0840	transmembrane signaling receptor activity
FM071_RS03035	COG0631	protein serine/threonine phosphatase activity
FM071_RS03040	COG2223	nitrite transmembrane transporter activity
FM071_RS03050	COG3302	dmso reductase anchor subunit
FM071_RS03060	COG0243	molybdopterin cofactor binding
FM071_RS03075	COG0528	UMP kinase activity
FM071_RS03080	COG1758	RNA polymerase activity
FM071_RS03090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FM071_RS03105	COG2404	hydrolase activity, acting on ester bonds
FM071_RS03110	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FM071_RS03120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FM071_RS03125	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FM071_RS03130	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FM071_RS03145	COG0134	indole-3-glycerol-phosphate synthase activity
FM071_RS03155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FM071_RS03165	COG0251	oxidation-reduction process
FM071_RS03170	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FM071_RS03175	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FM071_RS03180	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FM071_RS03185	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FM071_RS03190	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FM071_RS03195	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FM071_RS03195	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FM071_RS03200	COG1192	Involved in chromosome partitioning
FM071_RS03205	COG1475	DNA binding
FM071_RS03220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FM071_RS03225	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FM071_RS03230	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FM071_RS03235	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FM071_RS03240	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FM071_RS03245	COG0811	peptide transport
FM071_RS03250	COG0848	biopolymer transport protein
FM071_RS03260	COG0823	Involved in the tonB-independent uptake of proteins
FM071_RS03265	COG2885	chlorophyll binding
FM071_RS03275	COG1047	Peptidyl-prolyl cis-trans
FM071_RS03280	COG2204	response regulator
FM071_RS03285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FM071_RS03290	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FM071_RS03290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FM071_RS03295	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FM071_RS03300	COG0037	tRNA processing
FM071_RS03315	COG1714	RDD family
FM071_RS03320	COG0517	IMP dehydrogenase activity
FM071_RS03320	COG0516	GMP reductase activity
FM071_RS03335	COG0154	amidase activity
FM071_RS03340	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FM071_RS03345	COG1058	Belongs to the CinA family
FM071_RS03345	COG1546	Belongs to the CinA family
FM071_RS03380	COG0772	Belongs to the SEDS family
FM071_RS03385	COG0564	pseudouridine synthase activity
FM071_RS03395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FM071_RS03400	COG2884	Cell division ATP-binding protein ftsE
FM071_RS03415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FM071_RS03425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FM071_RS03430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FM071_RS03450	COG2151	metal-sulfur cluster biosynthetic enzyme
FM071_RS03470	COG1522	sequence-specific DNA binding
FM071_RS03475	COG1648	precorrin-2 dehydrogenase activity
FM071_RS03475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FM071_RS03485	COG1028	Short-chain dehydrogenase reductase Sdr
FM071_RS03495	COG0300	oxidoreductase activity
FM071_RS03515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FM071_RS03535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FM071_RS03535	COG1648	precorrin-2 dehydrogenase activity
FM071_RS03545	COG0535	radical SAM domain protein
FM071_RS03565	COG3256	nitric oxide reductase
FM071_RS03580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FM071_RS03580	COG0784	Response regulator, receiver
FM071_RS03580	COG2205	protein histidine kinase activity
FM071_RS03580	COG2198	Histidine kinase
FM071_RS03585	COG0275	rRNA processing
FM071_RS03595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FM071_RS03605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FM071_RS03620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FM071_RS03635	COG0217	transcriptional regulatory protein
FM071_RS03640	COG1739	Uncharacterized protein family UPF0029
FM071_RS03650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FM071_RS03670	COG4796	Type ii and iii secretion system protein
FM071_RS03705	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FM071_RS03710	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FM071_RS03715	COG0359	binds to the 23S rRNA
FM071_RS03725	COG0137	argininosuccinate synthase activity
FM071_RS03755	COG0408	coproporphyrinogen oxidase activity
FM071_RS03760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FM071_RS03770	COG0196	riboflavin kinase activity
FM071_RS03775	COG0585	pseudouridine synthase activity
FM071_RS03785	COG0500	methyltransferase
FM071_RS03790	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FM071_RS03790	COG2050	protein possibly involved in aromatic compounds catabolism
FM071_RS03810	COG2833	Protein of unknown function (DUF455)
FM071_RS03815	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FM071_RS03820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FM071_RS03825	COG1663	tetraacyldisaccharide 4'-kinase activity
FM071_RS03830	COG0531	amino acid
FM071_RS03850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FM071_RS03870	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FM071_RS03875	COG0442	prolyl-tRNA aminoacylation
FM071_RS03880	COG3030	protein affecting phage T7 exclusion by the F plasmid
FM071_RS03890	COG0181	hydroxymethylbilane synthase activity
FM071_RS03895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FM071_RS03905	COG0165	Argininosuccinate lyase
FM071_RS03920	COG0537	adenosine 5'-monophosphoramidase activity
FM071_RS03925	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FM071_RS03930	COG0072	phenylalanine-tRNA ligase activity
FM071_RS03930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FM071_RS03935	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FM071_RS03940	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FM071_RS03945	COG0539	negative regulation of cytoplasmic translation
FM071_RS03945	COG1185	polyribonucleotide nucleotidyltransferase activity
FM071_RS03960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FM071_RS03965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FM071_RS03970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FM071_RS03980	COG1331	Highly conserved protein containing a thioredoxin domain
FM071_RS03990	COG0531	amino acid
FM071_RS04045	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FM071_RS04050	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FM071_RS04055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FM071_RS04070	COG1355	regulation of microtubule-based process
FM071_RS04080	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FM071_RS04085	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FM071_RS04100	COG1331	Highly conserved protein containing a thioredoxin domain
FM071_RS04110	COG5002	protein histidine kinase activity
FM071_RS04120	COG4232	protein-disulfide reductase activity
FM071_RS04135	COG0642	Histidine kinase
FM071_RS04160	COG0737	Belongs to the 5'-nucleotidase family
FM071_RS04190	COG0513	Belongs to the DEAD box helicase family
FM071_RS04200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FM071_RS04205	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FM071_RS04210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FM071_RS04215	COG0343	queuine tRNA-ribosyltransferase activity
FM071_RS04220	COG5001	Diguanylate cyclase
FM071_RS04220	COG5002	protein histidine kinase activity
FM071_RS04225	COG0745	RESPONSE REGULATOR receiver
FM071_RS04240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FM071_RS04250	COG0587	DNA-directed DNA polymerase activity
FM071_RS04255	COG1362	aminopeptidase activity
FM071_RS04260	COG0642	Histidine kinase
FM071_RS04285	COG1333	cytochrome c biogenesis protein
FM071_RS04285	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FM071_RS04295	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FM071_RS04390	COG0582	viral genome integration into host DNA
FM071_RS04395	COG0824	Thioesterase
FM071_RS04405	COG1573	uracil-dna glycosylase
FM071_RS04410	COG3287	FIST C domain
FM071_RS04410	COG2200	EAL domain
FM071_RS04410	COG2199	diguanylate cyclase activity
FM071_RS04425	COG0751	glycine-tRNA ligase activity
FM071_RS04455	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FM071_RS04470	COG0101	tRNA pseudouridine synthase activity
FM071_RS04480	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FM071_RS04485	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FM071_RS04490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FM071_RS04505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FM071_RS04520	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FM071_RS04530	COG1338	Plays a role in the flagellum-specific transport system
FM071_RS04535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FM071_RS04550	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FM071_RS04560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FM071_RS04565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FM071_RS04575	COG0521	Mo-molybdopterin cofactor biosynthetic process
FM071_RS04595	COG0708	Exodeoxyribonuclease III
FM071_RS04600	COG2048	Heterodisulfide reductase, subunit B
FM071_RS04610	COG1053	succinate dehydrogenase
FM071_RS04625	COG0585	pseudouridine synthase activity
FM071_RS04655	COG1360	Flagellar Motor Protein
FM071_RS04660	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FM071_RS04670	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FM071_RS04675	COG3706	GGDEF domain
FM071_RS04680	COG0133	tryptophan synthase activity
FM071_RS04685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FM071_RS04695	COG0698	ribose 5-phosphate isomerase
FM071_RS04700	COG1994	Peptidase M50
FM071_RS04705	COG0681	Belongs to the peptidase S26 family
FM071_RS04710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FM071_RS04775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FM071_RS04795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FM071_RS04800	COG4786	Flagellar basal body rod
FM071_RS04805	COG4786	Flagellar basal body rod
FM071_RS04820	COG0066	3-isopropylmalate dehydratase activity
FM071_RS04825	COG0473	3-isopropylmalate dehydrogenase activity
FM071_RS04840	COG0788	formyltetrahydrofolate deformylase activity
FM071_RS04870	COG2171	N-acyltransferase activity
FM071_RS04890	COG1546	Belongs to the CinA family
FM071_RS04890	COG1058	Belongs to the CinA family
FM071_RS04900	COG0563	adenylate kinase activity
FM071_RS04905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FM071_RS04905	COG0301	tRNA thio-modification
FM071_RS04910	COG0563	adenylate kinase activity
FM071_RS04915	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FM071_RS04920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FM071_RS04935	COG1355	regulation of microtubule-based process
FM071_RS04960	COG0497	DNA recombination
FM071_RS04965	COG0084	hydrolase, TatD family'
FM071_RS04975	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FM071_RS04980	COG0131	Imidazoleglycerol-phosphate dehydratase
FM071_RS04985	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FM071_RS05000	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FM071_RS05020	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FM071_RS05025	COG0714	Associated with various cellular activities
FM071_RS05030	COG2863	cytochrome
FM071_RS05055	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FM071_RS05065	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FM071_RS05080	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FM071_RS05085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FM071_RS05090	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FM071_RS05090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FM071_RS05100	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FM071_RS05105	COG1763	Mo-molybdopterin cofactor biosynthetic process
FM071_RS05120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FM071_RS05125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FM071_RS05170	COG0778	Nitroreductase
FM071_RS05185	COG1309	transcriptional regulator
FM071_RS05200	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FM071_RS05200	COG0674	pyruvate-flavodoxin oxidoreductase activity
FM071_RS05210	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FM071_RS05215	COG0045	succinate-CoA ligase (ADP-forming) activity
FM071_RS05220	COG0114	fumarate hydratase activity
FM071_RS05225	COG0039	L-malate dehydrogenase activity
FM071_RS05235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FM071_RS05245	COG4591	ABC-type transport system involved in lipoprotein release permease component
FM071_RS05250	COG0653	protein targeting
FM071_RS05255	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FM071_RS05260	COG1049	propionate catabolic process, 2-methylcitrate cycle
FM071_RS05270	COG1674	ftsk spoiiie
FM071_RS05270	COG1196	nuclear chromosome segregation
FM071_RS05275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FM071_RS05290	COG0163	prenyltransferase activity
FM071_RS05295	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FM071_RS05300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FM071_RS05305	COG0124	histidyl-tRNA synthetase
FM071_RS05310	COG0069	glutamate synthase activity
FM071_RS05315	COG1166	arginine decarboxylase activity
FM071_RS05320	COG1045	serine acetyltransferase
FM071_RS05335	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FM071_RS05340	COG0440	acetolactate synthase activity
FM071_RS05345	COG0028	Belongs to the TPP enzyme family
FM071_RS05355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FM071_RS05360	COG1832	CoA-binding protein
FM071_RS05385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FM071_RS05420	COG0242	peptide deformylase activity
FM071_RS05425	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FM071_RS05430	COG1137	ATPase activity
FM071_RS05435	COG0802	atpase or kinase
FM071_RS05440	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FM071_RS05445	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FM071_RS05455	COG1032	radical SAM domain protein
FM071_RS05460	COG1022	Amp-dependent synthetase and ligase
FM071_RS05465	COG1227	inorganic diphosphatase activity
FM071_RS05475	COG3437	response regulator, receiver
FM071_RS05480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FM071_RS05485	COG0730	response to heat
FM071_RS05510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FM071_RS05520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FM071_RS05525	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FM071_RS05530	COG0352	thiamine-phosphate diphosphorylase activity
FM071_RS05535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FM071_RS05540	COG0493	'glutamate synthase
FM071_RS05545	COG0069	glutamate synthase activity
FM071_RS05545	COG0067	glutamate synthase
FM071_RS05545	COG0070	glutamate synthase
FM071_RS05560	COG2226	methyltransferase
FM071_RS05580	COG1752	Esterase of the alpha-beta hydrolase superfamily
FM071_RS05585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FM071_RS05610	COG0588	phosphoglycerate mutase activity
FM071_RS05620	COG0321	lipoyl(octanoyl) transferase activity
FM071_RS05625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FM071_RS05630	COG0508	dehydrogenase complex catalyzes the overall conversion of
FM071_RS05635	COG0022	dehydrogenase e1 component
FM071_RS05635	COG0508	dehydrogenase complex catalyzes the overall conversion of
FM071_RS05640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FM071_RS05655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FM071_RS05670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FM071_RS05675	COG1830	Aldolase
FM071_RS05685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FM071_RS05685	COG0574	Belongs to the PEP-utilizing enzyme family
FM071_RS05690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FM071_RS05745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FM071_RS05750	COG1252	NADH dehydrogenase
FM071_RS05770	COG0730	response to heat
FM071_RS05820	COG1730	sister chromatid segregation
FM071_RS05855	COG1086	Polysaccharide biosynthesis protein
FM071_RS05860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FM071_RS05875	COG0438	transferase activity, transferring glycosyl groups
FM071_RS05880	COG1132	(ABC) transporter
FM071_RS05885	COG0367	asparagine synthase
FM071_RS05905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FM071_RS05915	COG2226	methyltransferase
FM071_RS05920	COG0367	asparagine synthase
FM071_RS05925	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FM071_RS05930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FM071_RS05935	COG0579	oxidoreductase
FM071_RS05955	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FM071_RS05965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FM071_RS05985	COG0582	viral genome integration into host DNA
FM071_RS06040	COG3586	endonuclease activity
FM071_RS06055	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FM071_RS06130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FM071_RS06205	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FM071_RS06225	COG0739	heme binding
FM071_RS06235	COG0306	phosphate transporter
FM071_RS06265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FM071_RS06275	COG1181	Belongs to the D-alanine--D-alanine ligase family
FM071_RS06280	COG0632	four-way junction helicase activity
FM071_RS06290	COG0728	peptidoglycan biosynthetic process
FM071_RS06295	COG0215	cysteine-tRNA ligase activity
FM071_RS06305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FM071_RS06330	COG0167	dihydroorotate dehydrogenase activity
FM071_RS06335	COG0612	Peptidase, M16
FM071_RS06340	COG5001	Diguanylate cyclase
FM071_RS06340	COG1716	ATPase activity
FM071_RS06355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FM071_RS06360	COG1028	Short-chain dehydrogenase reductase Sdr
FM071_RS06365	COG0651	ATP synthesis coupled electron transport
FM071_RS06370	COG0651	ATP synthesis coupled electron transport
FM071_RS06395	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FM071_RS06425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FM071_RS06430	COG0750	zinc metalloprotease
FM071_RS06435	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FM071_RS06460	COG2081	HI0933 family
FM071_RS06485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FM071_RS06485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FM071_RS06510	COG4974	Belongs to the 'phage' integrase family
FM071_RS06525	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FM071_RS06530	COG1393	Belongs to the ArsC family
FM071_RS06550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FM071_RS06555	COG0243	molybdopterin cofactor binding
FM071_RS06565	COG0784	Response regulator, receiver
FM071_RS06565	COG0835	chemotaxis
FM071_RS06575	COG0511	ligase activity, forming carbon-carbon bonds
FM071_RS06575	COG5016	pyruvate
FM071_RS06600	COG0326	Molecular chaperone. Has ATPase activity
FM071_RS06610	COG0488	(ABC) transporter
FM071_RS06615	COG0471	metal ion transport
FM071_RS06620	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FM071_RS06640	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FM071_RS06645	COG0439	Biotin carboxylase
FM071_RS06650	COG1592	Rubrerythrin
FM071_RS06655	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FM071_RS06670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FM071_RS06675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FM071_RS06685	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FM071_RS06695	COG0484	heat shock protein binding
FM071_RS06705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FM071_RS06715	COG0849	cell division
FM071_RS06720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FM071_RS06725	COG0484	heat shock protein binding
FM071_RS06735	COG1136	(ABC) transporter
FM071_RS06735	COG0577	efflux transmembrane transporter activity
FM071_RS06755	COG2890	protein-(glutamine-N5) methyltransferase activity
FM071_RS06760	COG0501	Belongs to the peptidase M48B family
FM071_RS06775	COG0471	metal ion transport
FM071_RS06780	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FM071_RS06790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FM071_RS06795	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FM071_RS06810	COG0356	it plays a direct role in the translocation of protons across the membrane
FM071_RS06820	COG1418	mRNA catabolic process
FM071_RS06835	COG0552	protein localization to endoplasmic reticulum
FM071_RS06845	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FM071_RS06860	COG1580	Controls the rotational direction of flagella during chemotaxis
FM071_RS06865	COG0736	holo-[acyl-carrier-protein] synthase activity
FM071_RS06875	COG2863	cytochrome
FM071_RS06890	COG0436	Aminotransferase
FM071_RS06910	COG1193	negative regulation of DNA recombination
FM071_RS06915	COG2081	HI0933 family
FM071_RS06920	COG1704	LemA family
FM071_RS06940	COG0210	DNA helicase
FM071_RS06950	COG0525	valine-tRNA ligase activity
FM071_RS06955	COG0659	secondary active sulfate transmembrane transporter activity
FM071_RS06960	COG2200	EAL domain
FM071_RS06960	COG2199	diguanylate cyclase activity
FM071_RS06970	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FM071_RS06975	COG1610	YqeY-like protein
FM071_RS06980	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FM071_RS06990	COG2274	protein secretion by the type I secretion system
FM071_RS07015	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FM071_RS07045	COG0284	orotidine-5'-phosphate decarboxylase activity
FM071_RS07050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FM071_RS07055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FM071_RS07060	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FM071_RS07065	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FM071_RS07070	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FM071_RS07075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FM071_RS07080	COG1077	Cell shape determining protein MreB Mrl
FM071_RS07090	COG3713	MltA-interacting MipA family protein
FM071_RS07095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FM071_RS07115	COG0754	glutathionylspermidine amidase activity
FM071_RS07160	COG0166	Belongs to the GPI family
FM071_RS07175	COG0463	Glycosyl transferase, family 2
FM071_RS07175	COG1216	Glycosyl transferase, family 2
FM071_RS07180	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FM071_RS07185	COG1070	Carbohydrate kinase
FM071_RS07190	COG1028	Short-chain dehydrogenase reductase Sdr
FM071_RS07190	COG3347	Dehydrogenase
FM071_RS07200	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FM071_RS07205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FM071_RS07215	COG0489	protein tyrosine kinase activity
FM071_RS07220	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FM071_RS07225	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FM071_RS07225	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FM071_RS07230	COG0745	RESPONSE REGULATOR receiver
FM071_RS07245	COG0668	transmembrane transport
FM071_RS07250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FM071_RS07285	COG2501	S4 domain
FM071_RS07295	COG2827	Endonuclease containing a URI domain
FM071_RS07300	COG0745	RESPONSE REGULATOR receiver
FM071_RS07305	COG0784	Response regulator, receiver
FM071_RS07305	COG2205	protein histidine kinase activity
FM071_RS07305	COG5002	protein histidine kinase activity
FM071_RS07310	COG0242	peptide deformylase activity
FM071_RS07320	COG0446	pyridine nucleotide-disulphide oxidoreductase
FM071_RS07325	COG0308	aminopeptidase N
FM071_RS07330	COG0564	pseudouridine synthase activity
FM071_RS07345	COG0513	Belongs to the DEAD box helicase family
FM071_RS07350	COG2199	diguanylate cyclase activity
FM071_RS07350	COG2200	EAL domain
FM071_RS07365	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FM071_RS07370	COG0247	lactate metabolic process
FM071_RS07375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FM071_RS07380	COG1132	(ABC) transporter
FM071_RS07405	COG1442	glycosyl transferase family 8
FM071_RS07415	COG0515	serine threonine protein kinase
FM071_RS07420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FM071_RS07455	COG0438	transferase activity, transferring glycosyl groups
FM071_RS07460	COG0463	Glycosyl transferase, family 2
FM071_RS07470	COG0438	transferase activity, transferring glycosyl groups
FM071_RS07485	COG0859	PFAM glycosyl transferase family 9
FM071_RS07505	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FM071_RS07505	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FM071_RS07525	COG2217	Heavy metal translocating P-type atpase
FM071_RS07535	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FM071_RS07540	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FM071_RS07560	COG0512	Glutamine amidotransferase of anthranilate synthase
FM071_RS07565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FM071_RS07585	COG3951	Flagellar rod assembly protein muramidase FlgJ
FM071_RS07590	COG1706	bacterial-type flagellum-dependent cell motility
FM071_RS07595	COG0742	ribosomal rna small subunit methyltransferase
FM071_RS07605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FM071_RS07620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FM071_RS07630	COG0484	heat shock protein binding
FM071_RS07635	COG0138	bifunctional purine biosynthesis protein purh
FM071_RS07640	COG3706	GGDEF domain
FM071_RS07645	COG0205	6-phosphofructokinase activity
FM071_RS07650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FM071_RS07660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FM071_RS07665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FM071_RS07680	COG0557	exoribonuclease II activity
FM071_RS07690	COG0735	belongs to the Fur family
FM071_RS07695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FM071_RS07700	COG0481	GTPase activity
FM071_RS07705	COG1040	competence protein
FM071_RS07715	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FM071_RS07720	COG0443	Heat shock 70 kDa protein
FM071_RS07740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FM071_RS07750	COG2304	oxidoreductase activity
FM071_RS07800	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FM071_RS07810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FM071_RS07830	COG0793	Belongs to the peptidase S41A family
FM071_RS07835	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FM071_RS07840	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FM071_RS07845	COG0047	phosphoribosylformylglycinamidine synthase activity
FM071_RS07855	COG0204	Acyl-transferase
FM071_RS07860	COG1993	acr, cog1993
FM071_RS07865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FM071_RS07885	COG3787	Belongs to the UPF0306 family
FM071_RS07895	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FM071_RS07900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FM071_RS07910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FM071_RS07920	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FM071_RS07930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FM071_RS07935	COG1605	Chorismate mutase
FM071_RS07935	COG0077	Prephenate dehydratase
FM071_RS07945	COG0019	diaminopimelate decarboxylase activity
FM071_RS07955	COG0193	aminoacyl-tRNA hydrolase activity
FM071_RS07960	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FM071_RS07970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FM071_RS07980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FM071_RS07985	COG0540	Belongs to the ATCase OTCase family
FM071_RS07990	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FM071_RS07995	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FM071_RS08010	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FM071_RS08015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FM071_RS08025	COG0706	membrane insertase activity
FM071_RS08030	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FM071_RS08035	COG0594	ribonuclease P activity
FM071_RS08040	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FM071_RS08045	COG0542	response to heat
FM071_RS08055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FM071_RS08065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FM071_RS08080	COG2226	methyltransferase
FM071_RS08125	COG0776	regulation of translation
FM071_RS08135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FM071_RS08145	COG0306	phosphate transporter
FM071_RS08150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FM071_RS08165	COG0527	aspartate kinase activity
FM071_RS08170	COG0494	nUDIX hydrolase
FM071_RS08175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FM071_RS08180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FM071_RS08185	COG0805	protein transport
FM071_RS08190	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FM071_RS08200	COG2861	carbohydrate metabolic process
FM071_RS08205	COG0360	Binds together with S18 to 16S ribosomal RNA
FM071_RS08210	COG0629	single-stranded DNA binding
FM071_RS08215	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FM071_RS08220	COG2199	diguanylate cyclase activity
FM071_RS08240	COG0560	Phosphoserine phosphatase
FM071_RS08250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FM071_RS08270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FM071_RS08275	COG2264	protein methyltransferase activity
FM071_RS08280	COG0745	RESPONSE REGULATOR receiver
FM071_RS08285	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FM071_RS08290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FM071_RS08310	COG0628	permease
FM071_RS08315	COG2255	four-way junction helicase activity
FM071_RS08320	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FM071_RS08330	COG0159	tryptophan synthase activity
FM071_RS08365	COG0840	transmembrane signaling receptor activity
FM071_RS08400	COG2873	o-acetylhomoserine
FM071_RS08405	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FM071_RS08410	COG0542	response to heat
FM071_RS08415	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FM071_RS08450	COG2195	Cleaves the N-terminal amino acid of tripeptides
FM071_RS08455	COG0335	large ribosomal subunit rRNA binding
FM071_RS08460	COG0336	Belongs to the RNA methyltransferase TrmD family
FM071_RS08465	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FM071_RS08475	COG0228	four-way junction DNA binding
FM071_RS08480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FM071_RS08485	COG0564	pseudouridine synthase activity
FM071_RS08490	COG1519	Transferase
FM071_RS08490	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FM071_RS08500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FM071_RS08515	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FM071_RS08520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FM071_RS08525	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FM071_RS08530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FM071_RS08535	COG0210	DNA helicase
FM071_RS08550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FM071_RS08560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FM071_RS08570	COG0667	Aldo Keto reductase
FM071_RS08580	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FM071_RS08585	COG1185	polyribonucleotide nucleotidyltransferase activity
FM071_RS08595	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FM071_RS08615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FM071_RS08615	COG0519	Catalyzes the synthesis of GMP from XMP
FM071_RS08620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FM071_RS08625	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FM071_RS08640	COG0322	excinuclease ABC activity
FM071_RS08645	COG0840	transmembrane signaling receptor activity
FM071_RS08665	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FM071_RS08670	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FM071_RS08700	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FM071_RS08705	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FM071_RS08710	COG0752	glycyl-tRNA synthetase alpha subunit
FM071_RS08725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FM071_RS08730	COG0826	peptidase U32
FM071_RS08740	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FM071_RS08750	COG3118	belongs to the thioredoxin family
FM071_RS08760	COG0492	ferredoxin-NADP+ reductase activity
FM071_RS08765	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FM071_RS08775	COG1007	ATP synthesis coupled electron transport
FM071_RS08785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FM071_RS08790	COG0713	ATP synthesis coupled electron transport
FM071_RS08795	COG0839	Belongs to the complex I subunit 6 family
FM071_RS08800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FM071_RS08805	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FM071_RS08830	COG0649	NAD binding
FM071_RS08835	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FM071_RS08840	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FM071_RS08845	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FM071_RS08850	COG1222	aaa ATPase
FM071_RS08860	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FM071_RS08875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FM071_RS08890	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FM071_RS08895	COG1242	4 iron, 4 sulfur cluster binding
FM071_RS08910	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FM071_RS08910	COG0140	phosphoribosyl-ATP diphosphatase activity
FM071_RS08945	COG0573	inorganic phosphate transmembrane transporter activity
FM071_RS08950	COG0581	inorganic phosphate transmembrane transporter activity
FM071_RS08955	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FM071_RS08970	COG0174	glutamine synthetase
FM071_RS08975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FM071_RS08990	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FM071_RS08995	COG0444	Belongs to the ABC transporter superfamily
FM071_RS09000	COG0156	8-amino-7-oxononanoate synthase activity
FM071_RS09010	COG0424	maF-like protein
FM071_RS09020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FM071_RS09040	COG4654	Cytochrome c, class I
FM071_RS09055	COG1342	Belongs to the UPF0251 family
FM071_RS09060	COG4716	Myosin-crossreactive antigen
FM071_RS09065	COG1234	tRNA 3'-trailer cleavage
FM071_RS09075	COG1012	belongs to the aldehyde dehydrogenase family
FM071_RS09105	COG0792	nuclease activity
FM071_RS09120	COG3383	formate dehydrogenase (NAD+) activity
FM071_RS09130	COG0460	homoserine dehydrogenase
FM071_RS09135	COG0436	Aminotransferase
FM071_RS09150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FM071_RS09155	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FM071_RS09160	COG0254	rRNA binding
FM071_RS09175	COG0303	'Molybdopterin
FM071_RS09185	COG0602	queuosine metabolic process
FM071_RS09190	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FM071_RS09210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FM071_RS09215	COG0723	plastoquinol--plastocyanin reductase activity
FM071_RS09230	COG3300	MHYT domain
FM071_RS09230	COG5001	Diguanylate cyclase
FM071_RS09265	COG1309	transcriptional regulator
FM071_RS09270	COG0456	acetyltransferase
FM071_RS09310	COG0445	tRNA wobble uridine modification
FM071_RS09330	COG0514	ATP-dependent DNA helicase (RecQ)
FM071_RS09355	COG1854	S-ribosylhomocysteine lyase activity
FM071_RS09360	COG3706	GGDEF domain
FM071_RS09375	COG1013	pyruvate-flavodoxin oxidoreductase activity
FM071_RS09380	COG0674	pyruvate-flavodoxin oxidoreductase activity
FM071_RS09385	COG1144	Oxidoreductase
FM071_RS09390	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FM071_RS09405	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FM071_RS09410	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FM071_RS09420	COG0725	ABC transporter, periplasmic molybdate-binding protein
FM071_RS09435	COG3842	ATPase activity
FM071_RS09440	COG5001	Diguanylate cyclase
FM071_RS09440	COG5002	protein histidine kinase activity
FM071_RS09465	COG2226	methyltransferase
FM071_RS09470	COG4232	protein-disulfide reductase activity
FM071_RS09475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FM071_RS09485	COG1074	ATP-dependent DNA helicase activity
FM071_RS09525	COG3278	Belongs to the heme-copper respiratory oxidase family
FM071_RS09530	COG0505	Belongs to the CarA family
FM071_RS09550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FM071_RS09555	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FM071_RS09560	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FM071_RS09565	COG1968	undecaprenyl-diphosphatase activity
FM071_RS09570	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FM071_RS09575	COG2814	Major facilitator Superfamily
FM071_RS09590	COG2202	Pas domain
FM071_RS09590	COG3920	Histidine kinase
FM071_RS09605	COG1131	(ABC) transporter
FM071_RS09610	COG0348	domain, Protein
FM071_RS09625	COG0437	4 iron, 4 sulfur cluster binding
FM071_RS09640	COG4263	nitrous-oxide reductase activity
FM071_RS09660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FM071_RS09670	COG0129	dihydroxy-acid dehydratase activity
FM071_RS09715	COG1858	cytochrome C peroxidase
FM071_RS09725	COG5001	Diguanylate cyclase
FM071_RS09725	COG3300	MHYT domain
FM071_RS09730	COG5001	Diguanylate cyclase
FM071_RS09740	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FM071_RS09745	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FM071_RS09765	COG1472	Belongs to the glycosyl hydrolase 3 family
FM071_RS09775	COG1872	DUF167
FM071_RS09780	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FM071_RS09810	COG1393	Belongs to the ArsC family
FM071_RS09815	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FM071_RS09815	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FM071_RS09825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FM071_RS09830	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FM071_RS09830	COG2199	diguanylate cyclase activity
FM071_RS09845	COG1132	(ABC) transporter
FM071_RS09850	COG1194	a g-specific adenine glycosylase
FM071_RS09860	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FM071_RS09875	COG2270	Major facilitator Superfamily
FM071_RS09880	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FM071_RS09885	COG0642	Histidine kinase
FM071_RS09890	COG0745	RESPONSE REGULATOR receiver
FM071_RS09905	COG2132	Multicopper oxidase
FM071_RS09925	COG2217	Heavy metal translocating P-type atpase
FM071_RS09935	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FM071_RS09955	COG0069	glutamate synthase activity
FM071_RS09960	COG2259	Doxx family
FM071_RS09965	COG3437	response regulator, receiver
FM071_RS09965	COG0784	Response regulator, receiver
FM071_RS09995	COG3706	GGDEF domain
FM071_RS10000	COG0513	Belongs to the DEAD box helicase family
FM071_RS10010	COG0745	RESPONSE REGULATOR receiver
FM071_RS10015	COG0642	Histidine kinase
FM071_RS10030	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FM071_RS10030	COG0822	iron-sulfur transferase activity
FM071_RS10030	COG2906	2 iron, 2 sulfur cluster binding
FM071_RS10035	COG1104	cysteine desulfurase activity
FM071_RS10040	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FM071_RS10050	COG0746	molybdenum cofactor guanylyltransferase activity
FM071_RS10055	COG0315	cyclic pyranopterin monophosphate synthase activity
FM071_RS10085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FM071_RS10120	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FM071_RS10125	COG0571	ribonuclease III activity
FM071_RS10130	COG0328	RNA-DNA hybrid ribonuclease activity
FM071_RS10145	COG2855	membrane
FM071_RS10155	COG0348	domain, Protein
FM071_RS10165	COG0646	methionine synthase
FM071_RS10165	COG1410	methionine synthase
FM071_RS10170	COG0606	chelatase, subunit chli
FM071_RS10175	COG0242	peptide deformylase activity
FM071_RS10185	COG0740	serine-type endopeptidase activity
FM071_RS10190	COG0544	peptidyl-prolyl cis-trans isomerase activity
FM071_RS10195	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FM071_RS10200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FM071_RS10205	COG0268	Binds directly to 16S ribosomal RNA
FM071_RS10210	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FM071_RS10215	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FM071_RS10220	COG0237	dephospho-CoA kinase activity
FM071_RS10225	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FM071_RS10235	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FM071_RS10265	COG0670	Belongs to the BI1 family
FM071_RS10270	COG0352	thiamine-phosphate diphosphorylase activity
FM071_RS10280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FM071_RS10285	COG1121	(ABC) transporter
FM071_RS10290	COG3443	Belongs to the bacterial solute-binding protein 9 family
FM071_RS10290	COG0803	Belongs to the bacterial solute-binding protein 9 family
FM071_RS10295	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FM071_RS10300	COG0233	cytoplasmic translational termination
FM071_RS10305	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FM071_RS10315	COG0504	CTP synthase activity
FM071_RS10320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FM071_RS10330	COG1157	protein secretion by the type III secretion system
FM071_RS10335	COG0302	gtp cyclohydrolase
FM071_RS10340	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FM071_RS10345	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FM071_RS10355	COG0107	imidazoleglycerol-phosphate synthase activity
FM071_RS10365	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FM071_RS10370	COG0564	pseudouridine synthase activity
FM071_RS10375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FM071_RS10380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FM071_RS10390	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FM071_RS10400	COG3123	guanosine phosphorylase activity
FM071_RS10405	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FM071_RS10450	COG2356	endonuclease I
FM071_RS10480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FM071_RS10515	COG0375	protein maturation
FM071_RS10520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FM071_RS10520	COG1024	Enoyl-CoA hydratase
FM071_RS10525	COG0309	Hydrogenase expression formation protein (HypE)
FM071_RS10530	COG0409	Hydrogenase expression formation protein
FM071_RS10535	COG0298	carbon dioxide binding
FM071_RS10540	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FM071_RS10555	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FM071_RS10565	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FM071_RS10580	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FM071_RS10585	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FM071_RS10590	COG3259	Nickel-dependent hydrogenase
FM071_RS10595	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FM071_RS10605	COG4974	Belongs to the 'phage' integrase family
FM071_RS10680	COG1475	DNA binding
FM071_RS10685	COG1192	Involved in chromosome partitioning