locus-tag	class	description
CVO_RS00025	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CVO_RS00035	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CVO_RS00040	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CVO_RS00045	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CVO_RS00050	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CVO_RS00055	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
CVO_RS00060	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CVO_RS00065	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CVO_RS00070	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CVO_RS00075	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CVO_RS00085	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CVO_RS00090	ENOG4105C0P	Mg chelatase subunit ChlI
CVO_RS00115	ENOG4105HMI	Membrane
CVO_RS00125	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CVO_RS00130	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CVO_RS00135	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CVO_RS00150	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CVO_RS00155	ENOG41080AZ	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CVO_RS00160	ENOG4105CDV	Ompa motb domain protein
CVO_RS00165	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CVO_RS00175	ENOG4105C3J	Cysteine desulfurase
CVO_RS00185	ENOG4105D4A	Cell wall formation (By similarity)
CVO_RS00190	ENOG4105E63	Pfam:DUF178
CVO_RS00195	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CVO_RS00200	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CVO_RS00230	ENOG4107RN3	metallophosphoesterase
CVO_RS00245	ENOG4107XPZ	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CVO_RS00265	ENOG4105CJW	magnesium transporter
CVO_RS00280	ENOG4105EQD	regulatoR
CVO_RS00285	ENOG4105BZU	Histidine kinase
CVO_RS00290	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CVO_RS00320	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CVO_RS00330	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CVO_RS00335	ENOG4108UMR	transcriptional regulator AsnC family
CVO_RS00350	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CVO_RS00355	ENOG4105D3R	alkyl hydroperoxide reductase
CVO_RS00380	ENOG4105CK7	Sodium proline symporter
CVO_RS00385	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CVO_RS00460	ENOG4108F3G	Type I restriction-modification system, R subunit
CVO_RS00470	ENOG4107QTH	restriction modification system DNA specificity domain
CVO_RS00510	ENOG4105C01	Dihydroxy-acid dehydratase
CVO_RS00520	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CVO_RS00525	ENOG4107RDB	Major Facilitator
CVO_RS00530	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CVO_RS00535	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CVO_RS00540	ENOG4107UUH	Aminotransferase
CVO_RS00545	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
CVO_RS00550	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CVO_RS00560	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CVO_RS00565	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
CVO_RS00580	ENOG4107UIK	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
CVO_RS00605	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
CVO_RS00610	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CVO_RS00615	ENOG4108UJD	30S ribosomal protein S9
CVO_RS00620	ENOG4105DEF	Extracellular solute-binding protein, family 5
CVO_RS00625	ENOG4107XGZ	Hydrolase
CVO_RS00630	ENOG4105EJ5	oxidoreductase gamma subunit
CVO_RS00635	ENOG4105WGB	oxidoreductase, delta subunit
CVO_RS00640	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
CVO_RS00645	ENOG4105DDK	oxidoreductase, beta subunit
CVO_RS00650	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
CVO_RS00670	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CVO_RS00685	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CVO_RS00695	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CVO_RS00700	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CVO_RS00725	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CVO_RS00730	ENOG4107XWN	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CVO_RS00740	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CVO_RS00755	ENOG41082DI	50s ribosomal protein l31
CVO_RS00760	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CVO_RS00765	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CVO_RS00780	ENOG4105CHM	Aminotransferase
CVO_RS00785	ENOG4105D6E	homoserine dehydrogenase
CVO_RS00790	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CVO_RS00795	ENOG41082UM	UPF0102 protein
CVO_RS00810	ENOG4105EWC	Purine nucleoside phosphorylase
CVO_RS00815	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CVO_RS00825	ENOG4107YJQ	MAF-like protein
CVO_RS00830	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CVO_RS00835	ENOG4108JQ7	(ABC) transporter
CVO_RS00840	ENOG4108JQC	penicillin-binding protein 1A
CVO_RS00850	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CVO_RS00855	ENOG4105C5F	glutamine synthetase
CVO_RS00860	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CVO_RS00865	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CVO_RS00870	ENOG4105E2Z	phosphate ABC transporter (Permease
CVO_RS00875	ENOG4105C8U	phosphate abc transporter
CVO_RS00880	ENOG4105CSR	polyphosphate kinase 2
CVO_RS00885	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
CVO_RS00895	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CVO_RS00900	ENOG4107RIZ	hflk protein
CVO_RS00905	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CVO_RS00910	ENOG4105N5T	Radical SAM Protein
CVO_RS00915	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CVO_RS00920	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CVO_RS00925	ENOG4105C3M	thioredoxin reductase
CVO_RS00935	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
CVO_RS00940	ENOG4105CFP	Peptidase U32
CVO_RS00945	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CVO_RS00965	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
CVO_RS01000	ENOG4105C7H	Helicase, RecD TraA family
CVO_RS01015	ENOG4105NBF	ammecr1 domain protein
CVO_RS01020	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
CVO_RS01030	ENOG4108IJ6	ABC transporter
CVO_RS01035	ENOG4105E0C	molybdate abc transporter
CVO_RS01065	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CVO_RS01100	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
CVO_RS01105	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
CVO_RS01115	ENOG4107Y2X	deaminase
CVO_RS01120	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CVO_RS01125	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CVO_RS01150	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CVO_RS01155	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CVO_RS01160	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CVO_RS01165	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CVO_RS01185	ENOG4108IEH	NADH dehydrogenase subunit g
CVO_RS01190	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CVO_RS01195	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CVO_RS01205	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CVO_RS01210	ENOG4105D65	subunit l
CVO_RS01215	ENOG4105C8S	subunit m
CVO_RS01220	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CVO_RS01235	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CVO_RS01245	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CVO_RS01250	ENOG4105BZU	Histidine kinase
CVO_RS01255	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CVO_RS01260	ENOG4105CNI	cell division protein FtsW
CVO_RS01265	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CVO_RS01270	ENOG4107T5V	SNARE associated Golgi
CVO_RS01285	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CVO_RS01290	ENOG4105D05	Receptor
CVO_RS01305	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
CVO_RS01310	ENOG4105CIZ	coA-substrate-specific enzyme activase
CVO_RS01315	ENOG4105BZS	acriflavin resistance protein
CVO_RS01325	ENOG4105CE9	30S ribosomal protein S2
CVO_RS01330	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CVO_RS01340	ENOG4108I0Y	(ABC) transporter
CVO_RS01350	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CVO_RS01355	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CVO_RS01360	ENOG4105C75	arginyL-tRNA synthetase
CVO_RS01375	ENOG4107S6Z	Na H antiporter
CVO_RS01380	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CVO_RS01395	ENOG4107S8C	mandelate racemase muconate lactonizing
CVO_RS01405	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CVO_RS01420	ENOG4108UQY	Iron-storage protein
CVO_RS01425	ENOG4105EZM	VWA-like domain (DUF2201)
CVO_RS01435	ENOG4107QUV	Domain protein
CVO_RS01440	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CVO_RS01445	ENOG4105D3R	alkyl hydroperoxide reductase
CVO_RS01450	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CVO_RS01455	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CVO_RS01460	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CVO_RS01470	ENOG4105YQ2	50s ribosomal protein l32
CVO_RS01475	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CVO_RS01480	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CVO_RS01495	ENOG4105C1J	atp-dependent rna helicase
CVO_RS01510	ENOG4105VE1	Phosphatidylcholine synthase
CVO_RS01520	ENOG4107K9B	ferrous iron transport protein
CVO_RS01525	ENOG4105CE1	Ferrous iron transport protein b
CVO_RS01530	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CVO_RS01535	ENOG4105E0F	Histidine kinase
CVO_RS01555	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
CVO_RS01560	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CVO_RS01570	ENOG4105BZA	Phosphoglycerate kinase
CVO_RS01575	ENOG4105CP7	Triose-phosphate isomerase
CVO_RS01580	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CVO_RS01595	ENOG4105CHV	Transcription elongation factor NusA
CVO_RS01605	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CVO_RS01610	ENOG4105KB8	(LipO)protein
CVO_RS01615	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CVO_RS01640	ENOG4105BZS	acriflavin resistance protein
CVO_RS01645	ENOG4105CIZ	coA-substrate-specific enzyme activase
CVO_RS01650	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
CVO_RS01670	ENOG4105M15	transport protein ExbD
CVO_RS01675	ENOG4105M8K	biopolymer transport protein
CVO_RS01680	ENOG4105D05	Receptor
CVO_RS01685	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CVO_RS01690	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CVO_RS01695	ENOG4105CBX	hi0933 family
CVO_RS01710	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
CVO_RS01720	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CVO_RS01730	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CVO_RS01735	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CVO_RS01755	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CVO_RS01770	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CVO_RS01795	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CVO_RS01800	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CVO_RS01805	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CVO_RS01810	ENOG4105F4G	Membrane
CVO_RS01825	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CVO_RS01830	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CVO_RS01840	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CVO_RS01845	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CVO_RS01855	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CVO_RS01865	ENOG4105EAC	phosphoserine phosphatase
CVO_RS01875	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CVO_RS01880	ENOG4108UUM	single-stranded DNA-binding protein
CVO_RS01885	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CVO_RS01890	ENOG4105PXI	polysaccharide deacetylase
CVO_RS01900	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CVO_RS01905	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CVO_RS01915	ENOG4105CSA	Coproporphyrinogen iii oxidase
CVO_RS01920	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CVO_RS01925	ENOG4105CFH	Aspartokinase
CVO_RS01940	ENOG4105EEI	dihydropteroate synthase
CVO_RS01945	ENOG4105CFG	Acts as a chaperone (By similarity)
CVO_RS01950	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CVO_RS01960	ENOG4105BZU	Histidine kinase
CVO_RS01980	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CVO_RS01985	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CVO_RS01990	ENOG4105C8P	)-transporter
CVO_RS02020	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CVO_RS02025	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CVO_RS02030	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CVO_RS02035	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CVO_RS02040	ENOG4105CHR	reductase
CVO_RS02065	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CVO_RS02080	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CVO_RS02085	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CVO_RS02090	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CVO_RS02095	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CVO_RS02100	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CVO_RS02105	ENOG4105DJV	ribulose-phosphate 3-epimerase
CVO_RS02110	ENOG4105VB9	50S ribosomal protein l28
CVO_RS02120	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CVO_RS02125	ENOG4105EN6	Membrane
CVO_RS02130	ENOG4108Z0R	Transferase
CVO_RS02140	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CVO_RS02150	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CVO_RS02155	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CVO_RS02165	ENOG4105C8T	Leucyl-tRNA synthetase
CVO_RS02175	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CVO_RS02180	ENOG4105DR5	peptidase
CVO_RS02185	ENOG4108JA2	transcriptioN-repair coupling factor
CVO_RS02190	ENOG4105D48	metallophosphoesterase
CVO_RS02195	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CVO_RS02200	ENOG4105C08	Histidine kinase
CVO_RS02205	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CVO_RS02210	ENOG4108M8H	domain protein
CVO_RS02225	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CVO_RS02230	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CVO_RS02240	ENOG4105E0A	ABC, transporter
CVO_RS02245	ENOG4105EHG	Permease protein
CVO_RS02255	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CVO_RS02265	ENOG4105F4R	Transcriptional regulator mode
CVO_RS02275	ENOG4105DIK	(ABC) transporter
CVO_RS02285	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CVO_RS02290	ENOG4105D06	uba thif-type nad fad binding protein
CVO_RS02300	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CVO_RS02305	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CVO_RS02320	ENOG4105DHJ	ABC, transporter
CVO_RS02335	ENOG4107RAQ	aminopeptidase
CVO_RS02355	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
CVO_RS02370	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
CVO_RS02375	ENOG4105GXZ	Ferredoxin-type protein NapH
CVO_RS02380	ENOG4108BGM	Quinol dehydrogenase periplasmic component
CVO_RS02385	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CVO_RS02400	ENOG4105D82	Glutamate dehydrogenase
CVO_RS02420	ENOG4105C5H	ABC transporter
CVO_RS02425	ENOG4105VEQ	Cold shock protein
CVO_RS02430	ENOG4105WQ3	Rna-binding protein
CVO_RS02570	ENOG4105D82	Glutamate dehydrogenase
CVO_RS02605	ENOG4107RIQ	Sulfate adenylate transferase
CVO_RS02610	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CVO_RS02615	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CVO_RS02620	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CVO_RS02625	ENOG4105D1F	ATP-binding protein
CVO_RS02630	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CVO_RS02635	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CVO_RS02640	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CVO_RS02645	ENOG4105DVY	radical SAM domain protein
CVO_RS02655	ENOG4107ZAZ	Oligosaccharyl transferase, STT3 subunit
CVO_RS02660	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CVO_RS02665	ENOG4107QP8	phosphohexose isomerase
CVO_RS02670	ENOG4106032	Glutathionylspermidine synthase
CVO_RS02685	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CVO_RS02695	ENOG4105DFF	Rod shape-determining protein mreb
CVO_RS02700	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CVO_RS02705	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CVO_RS02710	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CVO_RS02715	ENOG4105WPN	DNA integration recombination invertion protein
CVO_RS02720	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CVO_RS02725	ENOG4105GR3	Histidine kinase
CVO_RS02745	ENOG41062QD	Membrane
CVO_RS02750	ENOG4107QN1	sodium solute
CVO_RS02760	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CVO_RS02765	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CVO_RS02770	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CVO_RS02780	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CVO_RS02785	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CVO_RS02790	ENOG4105KME	endoribonuclease L-psp
CVO_RS02810	ENOG4105E3S	small subunit
CVO_RS02815	ENOG4105DPX	Hydrogenase, large subunit
CVO_RS02820	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
CVO_RS02825	ENOG4108USZ	hydrogenase
CVO_RS02855	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
CVO_RS02860	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
CVO_RS02865	ENOG4105CQS	hydrogenase expression formation protein HypD
CVO_RS02875	ENOG4105C45	hydrogenase expression formation protein (HypE)
CVO_RS02880	ENOG4105F71	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CVO_RS02885	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
CVO_RS02890	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CVO_RS02895	ENOG4105K46	50S ribosomal protein l27
CVO_RS02900	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CVO_RS02905	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CVO_RS02910	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CVO_RS02920	ENOG4107QJE	Chromosome Partitioning Protein
CVO_RS02925	ENOG4105FA0	parb-like partition protein
CVO_RS02930	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
CVO_RS02940	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CVO_RS02945	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CVO_RS02950	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CVO_RS02955	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CVO_RS02960	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CVO_RS02965	ENOG4105E02	MotA TolQ exbB proton channel
CVO_RS02970	ENOG4105M8F	Biopolymer transport protein exbD tolR
CVO_RS02980	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CVO_RS02995	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CVO_RS03000	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CVO_RS03005	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CVO_RS03010	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CVO_RS03015	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CVO_RS03025	ENOG4105CDY	transcriptional regulatory protein
CVO_RS03035	ENOG4107QHF	type ii secretion system protein e
CVO_RS03055	ENOG4105E4G	Type IV pilus
CVO_RS03075	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CVO_RS03080	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CVO_RS03085	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CVO_RS03090	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CVO_RS03100	ENOG4105CDH	Citrulline--aspartate ligase
CVO_RS03110	ENOG4105CKW	Inner membrane protein yedI
CVO_RS03130	ENOG4105BZU	Histidine kinase
CVO_RS03135	ENOG4108STX	response regulator
CVO_RS03160	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CVO_RS03175	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CVO_RS03180	ENOG4105DX0	Hemolysin A
CVO_RS03195	ENOG4105DTN	riboflavin biosynthesis protein ribF
CVO_RS03205	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
CVO_RS03215	ENOG4105BZU	Histidine kinase
CVO_RS03220	ENOG4106TD9	Diguanylate cyclase
CVO_RS03235	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CVO_RS03240	ENOG4107SVH	Potassium channel protein
CVO_RS03250	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CVO_RS03265	ENOG4105DHQ	Histidine kinase
CVO_RS03270	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CVO_RS03315	ENOG4105C19	ABC transporter
CVO_RS03320	ENOG4105D78	K07001 NTE family protein
CVO_RS03330	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
CVO_RS03335	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CVO_RS03360	ENOG4105C19	ABC transporter
CVO_RS03375	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CVO_RS03380	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
CVO_RS03400	ENOG4108M15	ABC transporter
CVO_RS03420	ENOG4108BGM	Quinol dehydrogenase periplasmic component
CVO_RS03435	ENOG4105EQJ	Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide (By similarity)
CVO_RS03455	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CVO_RS03460	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CVO_RS03475	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CVO_RS03485	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CVO_RS03490	ENOG4105CA3	membrane-bound lytic murein transglycosylase
CVO_RS03495	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CVO_RS03500	ENOG410903C	(LipO)protein
CVO_RS03515	ENOG4105BZU	Histidine kinase
CVO_RS03520	ENOG4107XM9	(LipO)protein
CVO_RS03530	ENOG4105E3S	small subunit
CVO_RS03535	ENOG4105DPX	Hydrogenase, large subunit
CVO_RS03565	ENOG4105KPV	Transcriptional regulator
CVO_RS03570	ENOG4108VKQ	nitriC oxide reductase
CVO_RS03580	ENOG4105FAE	von Willebrand factor, type A
CVO_RS03600	ENOG4105E2X	shikimate dehydrogenase
CVO_RS03605	ENOG4105CRQ	synthase (Component I)
CVO_RS03615	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CVO_RS03620	ENOG4105CRK	lysyL-tRNA synthetase
CVO_RS03635	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
CVO_RS03640	ENOG4105C5H	ABC transporter
CVO_RS03645	ENOG4105CY0	Metallo-Beta-Lactamase
CVO_RS03655	ENOG4108M6U	Universal stress protein A
CVO_RS03660	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CVO_RS03675	ENOG4105VCH	membrane
CVO_RS03685	ENOG4107QSA	Oxaloacetate decarboxylase
CVO_RS03690	ENOG4105D9Q	decarboxylase (Beta subunit)
CVO_RS03700	ENOG4108J2R	molybdopterin oxidoreductase
CVO_RS03705	ENOG4105C8Y	Acetylornithine aminotransferase
CVO_RS03720	ENOG4105CZX	twitching motility protein
CVO_RS03725	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CVO_RS03735	ENOG4108TX7	
CVO_RS03740	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CVO_RS03760	ENOG4105C2M	dna polymerase I
CVO_RS03765	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
CVO_RS03770	ENOG4105ETX	regulatoR
CVO_RS03775	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CVO_RS03790	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CVO_RS03795	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CVO_RS03800	ENOG4105CBX	hi0933 family
CVO_RS03815	ENOG4105DFA	alanine racemase domain protein
CVO_RS03820	ENOG4105DZP	Membrane-associated zinc metalloprotease
CVO_RS03825	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CVO_RS03830	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CVO_RS03835	ENOG4105DEU	major facilitator superfamily
CVO_RS03840	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
CVO_RS03850	ENOG4105DCF	alanine dehydrogenase
CVO_RS03855	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CVO_RS03865	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CVO_RS03895	ENOG4105VEQ	Cold shock protein
CVO_RS03920	ENOG4105EYH	Exonuclease
CVO_RS03930	ENOG4105PGM	cation diffusion facilitator family transporter
CVO_RS03945	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CVO_RS03950	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CVO_RS03960	ENOG4105D49	3-dehydroquinate synthase
CVO_RS03970	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CVO_RS03975	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CVO_RS03985	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CVO_RS04005	ENOG4107PU6	Membrane
CVO_RS04015	ENOG41086B8	CoB-CoM heterodisulfide reductase
CVO_RS04045	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
CVO_RS04055	ENOG4105D0S	secretion protein (HlyD
CVO_RS04060	ENOG4105CJ1	ABC, transporter
CVO_RS04065	ENOG4105CMI	transporter
CVO_RS04070	ENOG4105C3G	gtp-binding protein
CVO_RS04145	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
CVO_RS04150	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CVO_RS04155	ENOG4105CA9	Pyruvate kinase
CVO_RS04160	ENOG4107QP8	phosphohexose isomerase
CVO_RS04180	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
CVO_RS04190	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CVO_RS04200	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CVO_RS04205	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CVO_RS04225	ENOG4105CPP	Dehydrogenase, E1 component
CVO_RS04235	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CVO_RS04240	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
CVO_RS04245	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CVO_RS04255	ENOG4105BZU	Histidine kinase
CVO_RS04275	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CVO_RS04280	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CVO_RS04285	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CVO_RS04290	ENOG4108YZG	isomerase
CVO_RS04295	ENOG4108Z4T	Peptidase M50
CVO_RS04300	ENOG4105C3F	Signal peptidase i
CVO_RS04305	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CVO_RS04325	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CVO_RS04345	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CVO_RS04350	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
CVO_RS04355	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CVO_RS04360	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CVO_RS04365	ENOG4105CIY	formyltetrahydrofolate deformylase
CVO_RS04390	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
CVO_RS04410	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CVO_RS04415	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CVO_RS04420	ENOG4105C9M	aspartyl-trna synthetase
CVO_RS04425	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CVO_RS04435	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CVO_RS04440	ENOG4105F8V	Hydrolase, tatD family
CVO_RS04445	ENOG4105E9H	Lytic Murein transglycosylase
CVO_RS04450	ENOG4105K6T	rare lipoprotein A
CVO_RS04455	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CVO_RS04460	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
CVO_RS04475	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CVO_RS04485	ENOG4107RF6	penicillin-binding protein
CVO_RS04495	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CVO_RS04500	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CVO_RS04510	ENOG4105CH5	extracellular solute-binding protein, family 7
CVO_RS04520	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CVO_RS04530	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CVO_RS04550	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CVO_RS04555	ENOG4105CX6	glutaminyL-tRNA synthetase
CVO_RS04590	ENOG4105DQU	oxidoreductase, subunit beta
CVO_RS04595	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
CVO_RS04605	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CVO_RS04610	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CVO_RS04615	ENOG4105C9Q	fumarate hydratase class II
CVO_RS04620	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CVO_RS04625	ENOG4105E9K	Isocitrate dehydrogenase
CVO_RS04630	ENOG4105HHA	aminodeoxychorismate lyase
CVO_RS04640	ENOG4105D60	lipoprotein releasing system transmembrane protein
CVO_RS04645	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CVO_RS04650	ENOG4105ZGC	lipoprotein carrier protein
CVO_RS04655	ENOG4107QIJ	Aconitate hydratase 2
CVO_RS04665	ENOG4105CNU	cell division protein FtsK
CVO_RS04675	ENOG4105VTR	Integrase
CVO_RS04755	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CVO_RS04760	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CVO_RS04765	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CVO_RS04770	ENOG4108TQ9	Histidine kinase
CVO_RS04775	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CVO_RS04780	ENOG4105CUT	histidyl-tRNA synthetase
CVO_RS04785	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
CVO_RS04790	ENOG4105D7W	serine acetyltransferase
CVO_RS04800	ENOG4105CHH	sulfate transporter
CVO_RS04825	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CVO_RS04830	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CVO_RS04835	ENOG4108ZP8	Acetolactate synthase small subunit
CVO_RS04840	ENOG4105C7K	acetolactate synthase
CVO_RS04845	ENOG4105C7B	Threonine dehydratase
CVO_RS04850	ENOG4105K4P	CoA-binding domain protein
CVO_RS04860	ENOG4108IUZ	ABC transporter
CVO_RS04865	ENOG4105K8N	protein family UPF0079, ATPase
CVO_RS04870	ENOG4107QYG	anthranilate phosphoribosyltransferase
CVO_RS04875	ENOG410854I	s4 domain protein
CVO_RS04885	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CVO_RS04900	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
CVO_RS04910	ENOG4107NA1	Endonuclease Exonuclease phosphatase
CVO_RS04915	ENOG4108RCM	Nitroreductase
CVO_RS04925	ENOG4105CGD	Nad-dependent epimerase dehydratase
CVO_RS04930	ENOG4105CUY	Mechanosensitive ion channel
CVO_RS04935	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
CVO_RS04940	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
CVO_RS04945	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CVO_RS04950	ENOG4105HF0	Membrane
CVO_RS04970	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CVO_RS04985	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CVO_RS04990	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CVO_RS04995	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CVO_RS05000	ENOG4105BZ8	glutamate synthase
CVO_RS05005	ENOG4105CBC	glutamate synthase
CVO_RS05065	ENOG4105CJW	magnesium transporter
CVO_RS05090	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CVO_RS05100	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
CVO_RS05110	ENOG4105CPF	Cell wall formation (By similarity)
CVO_RS05115	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CVO_RS05120	ENOG4105CJR	Integral membrane protein (MviN
CVO_RS05125	ENOG4105C8N	cysteinyl-tRNA synthetase
CVO_RS05130	ENOG4105CEP	NADH dehydrogenase
CVO_RS05145	ENOG4106YN8	Prenyltransferase
CVO_RS05155	ENOG4105IQ5	FAD linked oxidase domain protein
CVO_RS05160	ENOG4108RG3	short-chain dehydrogenase reductase
CVO_RS05170	ENOG41083B3	HAD-superfamily subfamily IB hydrolase
CVO_RS05180	ENOG4105D75	Capsular exopolysaccharide family
CVO_RS05190	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CVO_RS05200	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CVO_RS05205	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
CVO_RS05235	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CVO_RS05240	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CVO_RS05245	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CVO_RS05250	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
CVO_RS05260	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CVO_RS05270	ENOG4107S90	membrAne
CVO_RS05300	ENOG4107YD3	Thioesterase
CVO_RS05305	ENOG4105VTR	Integrase
CVO_RS05365	ENOG4105DZR	Type I site-specific deoxyribonuclease
CVO_RS05370	ENOG4105CB5	ATP-dependent DNA helicase recG
CVO_RS05375	ENOG4105DB4	
CVO_RS05380	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CVO_RS05435	ENOG4105BZ1	(ABC) transporter
CVO_RS05440	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
CVO_RS05445	ENOG4108UAJ	Transcriptional regulator
CVO_RS05470	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CVO_RS05475	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CVO_RS05485	ENOG4105CRE	cytochrome C
CVO_RS05495	ENOG4105DFM	M18 family aminopeptidase
CVO_RS05500	ENOG4105VZ9	UPF0235 protein
CVO_RS05510	ENOG4105C0B	DNA polymerase III (alpha subunit)
CVO_RS05515	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CVO_RS05520	ENOG4105CEP	NADH dehydrogenase
CVO_RS05525	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CVO_RS05535	ENOG4105CD3	dihydroorotase
CVO_RS05545	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CVO_RS05550	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CVO_RS05560	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CVO_RS05565	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CVO_RS05570	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CVO_RS05580	ENOG4105C7Z	Conserved Protein
CVO_RS05585	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CVO_RS05590	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CVO_RS05605	ENOG4105DIN	metallophosphoesterase
CVO_RS05610	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CVO_RS05615	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CVO_RS05620	ENOG4108VHG	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CVO_RS05635	ENOG4107V40	secretion protein, HlyD family
CVO_RS05655	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CVO_RS05660	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CVO_RS05665	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CVO_RS05670	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CVO_RS05675	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CVO_RS05690	ENOG4105CH7	arginosuccinase
CVO_RS05700	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CVO_RS05705	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CVO_RS05720	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CVO_RS05725	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CVO_RS05730	ENOG4105EAH	synthase
CVO_RS05745	ENOG4105CAS	nag kinase
CVO_RS05750	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CVO_RS05755	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CVO_RS05760	ENOG4105C4K	Nad synthetase
CVO_RS05770	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
CVO_RS05775	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
CVO_RS05785	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
CVO_RS05795	ENOG4105K63	Thioredoxin
CVO_RS05800	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CVO_RS05805	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CVO_RS05815	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CVO_RS05820	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CVO_RS05825	ENOG4108Z86	Glutamine amidotransferase
CVO_RS05835	ENOG4105DZR	Type I site-specific deoxyribonuclease
CVO_RS05850	ENOG4105EKX	Restriction modification system DNA (Specificity
CVO_RS05855	ENOG4105CVR	type I restriction-modification system
CVO_RS05875	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CVO_RS05885	ENOG4105VG1	fes assembly suf system protein
CVO_RS05900	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CVO_RS05910	ENOG4107QID	Threonine synthase
CVO_RS05930	ENOG4105CAK	Cell division ATP-binding protein ftsE
CVO_RS05935	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CVO_RS05945	ENOG4105C34	Pseudouridine synthase
CVO_RS05950	ENOG4105CNI	cell division protein FtsW
CVO_RS05985	ENOG4105CEV	competence damage-inducible protein
CVO_RS05990	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CVO_RS06100	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CVO_RS06105	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CVO_RS06120	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CVO_RS06125	ENOG4108NKP	c4-dicarboxylate transporter malic acid transport protein
CVO_RS06140	ENOG4105DWV	Homoserine O-trans-acetylase
CVO_RS06155	ENOG4105CUZ	uba thif-type nad fad binding protein
CVO_RS06160	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
CVO_RS06170	ENOG4105DFU	Cell wall formation (By similarity)
CVO_RS06180	ENOG4105C98	muts2 protein
CVO_RS06185	ENOG4105CBX	hi0933 family
CVO_RS06195	ENOG4108V0P	LemA family
CVO_RS06220	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CVO_RS06225	ENOG4105VBD	cytochrome C, class I
CVO_RS06235	ENOG4105ENA	helicase
CVO_RS06250	ENOG4108BGM	Quinol dehydrogenase periplasmic component
CVO_RS06255	ENOG4105GXZ	Ferredoxin-type protein NapH
CVO_RS06265	ENOG4108RAC	Rubrerythrin
CVO_RS06280	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CVO_RS06285	ENOG4105CHH	sulfate transporter
CVO_RS06295	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CVO_RS06310	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
CVO_RS06315	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CVO_RS06325	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CVO_RS06335	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
CVO_RS06340	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CVO_RS06350	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CVO_RS06360	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CVO_RS06365	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CVO_RS06385	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CVO_RS06390	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CVO_RS06400	ENOG4105D9P	serine threonine protein kinase
CVO_RS06420	ENOG4105DGW	oligopeptidase A
CVO_RS06455	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CVO_RS06465	ENOG4105DD5	Flagellar motor switch protein
CVO_RS06470	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CVO_RS06475	ENOG4107R21	site-determining protein
CVO_RS06480	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CVO_RS06485	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CVO_RS06490	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CVO_RS06510	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CVO_RS06515	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CVO_RS06520	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CVO_RS06525	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CVO_RS06535	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CVO_RS06545	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CVO_RS06555	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CVO_RS06570	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CVO_RS06580	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CVO_RS06590	ENOG4105ETX	regulatoR
CVO_RS06600	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CVO_RS06610	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CVO_RS06645	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CVO_RS06700	ENOG4105BZU	Histidine kinase
CVO_RS06715	ENOG4108YZA	Nitrogen regulatory protein pii
CVO_RS06720	ENOG4105BZU	Histidine kinase
CVO_RS06735	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CVO_RS06745	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CVO_RS06750	ENOG41082XB	radical SAM domain protein
CVO_RS06765	ENOG4105D7X	high-affinity nickel-transporter
CVO_RS06775	ENOG4105BZU	Histidine kinase
CVO_RS06780	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CVO_RS06790	ENOG4105CD8	aminopeptidase N
CVO_RS06800	ENOG4107QKV	phosphomannomutase
CVO_RS06805	ENOG4105EKE	dihydroorotase
CVO_RS06810	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CVO_RS06820	ENOG4105M8K	biopolymer transport protein
CVO_RS06825	ENOG4105M15	transport protein ExbD
CVO_RS06835	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
CVO_RS06845	ENOG4105BZU	Histidine kinase
CVO_RS06850	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CVO_RS06855	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CVO_RS06880	ENOG4105DR9	pseudouridine synthase
CVO_RS06885	ENOG4105C1J	atp-dependent rna helicase
CVO_RS06895	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CVO_RS06900	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CVO_RS06905	ENOG4105D4P	Coproporphyrinogen iii oxidase
CVO_RS06910	ENOG4105BZ1	(ABC) transporter
CVO_RS06915	ENOG4105D16	lipopolysaccharide heptosyltransferase i
CVO_RS06920	ENOG41080IJ	Diacylglycerol kinase
CVO_RS06930	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
CVO_RS06945	ENOG4106WTF	Glycosyl transferase, family 2
CVO_RS06950	ENOG4107QPH	glycogen) synthase
CVO_RS06955	ENOG4105CPK	Glycosyl transferase (Group 1
CVO_RS06975	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CVO_RS06985	ENOG4105VBD	cytochrome C, class I
CVO_RS07010	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CVO_RS07045	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CVO_RS07060	ENOG4105DDQ	anthranilate synthase
CVO_RS07065	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CVO_RS07070	ENOG4106H78	methyltransferase
CVO_RS07075	ENOG4108JDX	DNA polymerase iii, epsilon subunit
CVO_RS07085	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CVO_RS07095	ENOG4105DVC	DnaJ domain protein
CVO_RS07100	ENOG4105D0M	Protease HtpX homolog
CVO_RS07105	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CVO_RS07110	ENOG4105CTQ	phosphohexokinase
CVO_RS07115	ENOG4105EGD	dinuclear metal center protein, YbgI family
CVO_RS07120	ENOG4108RPX	mosc domain containing protein
CVO_RS07125	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
CVO_RS07140	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CVO_RS07150	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CVO_RS07175	ENOG4105RV9	Transcriptional regulator
CVO_RS07180	ENOG4105C08	Histidine kinase
CVO_RS07185	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CVO_RS07190	ENOG4105C1A	potassium transporter peripheral membrane
CVO_RS07195	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CVO_RS07200	ENOG4105GSH	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CVO_RS07205	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CVO_RS07215	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CVO_RS07220	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CVO_RS07225	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CVO_RS07230	ENOG4105VG0	50S ribosomal protein l34
CVO_RS07235	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CVO_RS07240	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CVO_RS07250	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
CVO_RS07265	ENOG410841J	DNA-binding protein Hu
CVO_RS07270	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CVO_RS07275	ENOG4105CJ3	phosphate transporter
CVO_RS07280	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CVO_RS07285	ENOG4107QY8	reductase
CVO_RS07295	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CVO_RS07300	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CVO_RS07315	ENOG4105FQT	
CVO_RS07325	ENOG4105CN1	protease
CVO_RS07330	ENOG4105C8V	SAICAR synthetase
CVO_RS07335	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
CVO_RS07340	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
CVO_RS07350	ENOG4105E9Q	Acyl-transferase
CVO_RS07355	ENOG4105WMR	Protein CrcB homolog
CVO_RS07360	ENOG4107H6U	ABC transporter
CVO_RS07370	ENOG4108ZPB	UPF0306 protein
CVO_RS07375	ENOG4105C87	Aminotransferase class I and II
CVO_RS07390	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CVO_RS07400	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CVO_RS07405	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CVO_RS07410	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CVO_RS07415	ENOG4105CQC	Prephenate dehydratase
CVO_RS07420	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
CVO_RS07425	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CVO_RS07435	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CVO_RS07440	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CVO_RS07445	ENOG4105CZX	twitching motility protein
CVO_RS07465	ENOG4105CXT	aspartate transcarbamylase
CVO_RS07470	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CVO_RS07475	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CVO_RS07485	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CVO_RS07510	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CVO_RS07515	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CVO_RS07520	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CVO_RS07525	ENOG4105VB6	UPF0109 protein
CVO_RS07530	ENOG4105K5M	30s ribosomal protein S16
CVO_RS07535	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CVO_RS07540	ENOG4108UPT	UPF0178 protein
CVO_RS07545	ENOG41082IR	Excinuclease ABC C subunit domain protein
CVO_RS07550	ENOG4105EI2	Pseudouridine synthase
CVO_RS07555	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CVO_RS07565	ENOG4105EGD	dinuclear metal center protein, YbgI family
CVO_RS07575	ENOG4105DR5	peptidase
CVO_RS07580	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CVO_RS07585	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CVO_RS07590	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CVO_RS07595	ENOG4105C4R	Atp-dependent dna helicase
CVO_RS07600	ENOG4105DUM	transcriptional regulator, lysR family
CVO_RS07625	ENOG4105HDD	phospholipase
CVO_RS07635	ENOG41084IH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CVO_RS07640	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CVO_RS07650	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CVO_RS07660	ENOG4105C12	Phosphoribosylglycinamide synthetase
CVO_RS07670	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CVO_RS07675	ENOG4108IYU	L-aspartate oxidase
CVO_RS07690	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CVO_RS07700	ENOG4105BZU	Histidine kinase
CVO_RS07705	ENOG4107QQR	Sporulation
CVO_RS07710	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CVO_RS07715	ENOG410901F	(LipO)protein
CVO_RS07740	ENOG4105MS2	ribosomal subunit Interface protein
CVO_RS07745	ENOG4105CB5	ATP-dependent DNA helicase recG
CVO_RS07755	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
CVO_RS07760	ENOG4105M7K	Involved in the transcription termination process (By similarity)
CVO_RS07765	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CVO_RS07790	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CVO_RS07810	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CVO_RS07815	ENOG4108YXA	Membrane
CVO_RS07825	ENOG4105C31	Tryptophanyl-tRNA synthetase
CVO_RS07830	ENOG4105DBV	ornithine carbamoyltransferase
CVO_RS07835	ENOG4105D52	delta-aminolevulinic acid dehydratase
CVO_RS07840	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
CVO_RS07845	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CVO_RS07860	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CVO_RS07865	ENOG4105DWY	Agmatine deiminase
CVO_RS07875	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CVO_RS07880	ENOG4105CDU	Replicative dna helicase
CVO_RS07885	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
CVO_RS07890	ENOG4107S2Z	UPF0761 membrane protein
CVO_RS07895	ENOG4105CQB	FAD linked oxidase domain protein
CVO_RS07905	ENOG4105DR5	peptidase
CVO_RS07910	ENOG4107VIJ	nudix hydrolase
CVO_RS07915	ENOG4105C25	Primosomal protein n'
CVO_RS07930	ENOG4105X0D	Fimbrial protein
CVO_RS07945	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CVO_RS07950	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CVO_RS07970	ENOG4105D05	Receptor
CVO_RS07980	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CVO_RS07985	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CVO_RS07990	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CVO_RS07995	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CVO_RS08000	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CVO_RS08005	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CVO_RS08010	ENOG4108VZM	50s ribosomal protein L10
CVO_RS08015	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CVO_RS08020	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CVO_RS08025	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CVO_RS08040	ENOG41084ED	50S ribosomal protein L33
CVO_RS08045	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CVO_RS08070	ENOG410802Z	Protein of unknown function (DUF328)
CVO_RS08085	ENOG4105DAN	ATP-dependent protease
CVO_RS08090	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CVO_RS08120	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
CVO_RS08125	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CVO_RS08130	ENOG4105CTB	Polyprenyl synthetase
CVO_RS08135	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CVO_RS08140	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
CVO_RS08150	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CVO_RS08160	ENOG41083MR	nifu domain-containing protein
CVO_RS08170	ENOG4108ZT0	50S ribosomal protein l17
CVO_RS08175	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CVO_RS08180	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CVO_RS08185	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CVO_RS08190	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CVO_RS08215	ENOG4105E0M	Sulfatase
CVO_RS08220	ENOG4105E0M	Sulfatase
CVO_RS08230	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CVO_RS08250	ENOG41085FC	arsR family transcriptional regulator
CVO_RS08255	ENOG4108UXE	Protein tyrosine phosphatase
CVO_RS08260	ENOG4107R5R	arsenical pump membrane protein
CVO_RS08275	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CVO_RS08280	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CVO_RS08285	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CVO_RS08290	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CVO_RS08295	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CVO_RS08300	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CVO_RS08310	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CVO_RS08315	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CVO_RS08320	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CVO_RS08325	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CVO_RS08330	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CVO_RS08335	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CVO_RS08340	ENOG41084HJ	50s ribosomal protein l29
CVO_RS08345	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CVO_RS08350	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CVO_RS08355	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CVO_RS08360	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CVO_RS08365	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CVO_RS08370	ENOG4105KZZ	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CVO_RS08375	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CVO_RS08380	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CVO_RS08385	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CVO_RS08395	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CVO_RS08400	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CVO_RS08405	ENOG4108ZEX	molybdopterin converting factor, subunit 2
CVO_RS08415	ENOG4108XUR	Pfam:DUF178
CVO_RS08420	ENOG4105C6K	Malic enzyme
CVO_RS08475	ENOG4105K64	Glycosyl transferase, family 2
CVO_RS08480	ENOG4105CMR	udp-glucose 4-epimerase
CVO_RS08495	ENOG41068W6	Capsular polysaccharide biosynthesis protein
CVO_RS08525	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
CVO_RS08545	ENOG4108IAJ	Nad-dependent epimerase dehydratase
CVO_RS08550	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CVO_RS08560	ENOG4105FAW	cDP-glucose 4,6-dehydratase
CVO_RS08565	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
CVO_RS08570	ENOG4105C30	Nad-dependent epimerase dehydratase
CVO_RS08580	ENOG4105FGF	GDP-mannose mannosyl hydrolase
CVO_RS08670	ENOG4105BZG	amino acid carrier protein
CVO_RS08675	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CVO_RS08680	ENOG4108ENG	carbohydrate kinase, YjeF related protein
CVO_RS08690	ENOG4105CA0	peroxidase
CVO_RS08695	ENOG4105C2X	Arabinose 5-phosphate isomerase
CVO_RS08700	ENOG4105FE9	pseudouridine synthase
CVO_RS08705	ENOG4105D1H	recombination factor protein RarA
CVO_RS08710	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CVO_RS08715	ENOG41084M8	50s ribosomal protein L35
CVO_RS08735	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
CVO_RS08740	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CVO_RS08750	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CVO_RS08785	ENOG4105CAQ	asparagine synthetase
CVO_RS08790	ENOG4107B2H	carbonic anhydrase
CVO_RS08800	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CVO_RS08825	ENOG4105DZS	Phenylacetate-CoA ligase
CVO_RS08855	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CVO_RS08870	ENOG4105C5H	ABC transporter
CVO_RS08875	ENOG4108VKG	metal-dependent hydrolase
CVO_RS08880	ENOG4105C1J	atp-dependent rna helicase
CVO_RS08890	ENOG4105CGY	Dna recombination protein
CVO_RS08910	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CVO_RS08915	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CVO_RS08940	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
CVO_RS08945	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CVO_RS08950	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CVO_RS08955	ENOG4105KNE	Phosphatidate cytidylyltransferase
CVO_RS08965	ENOG4105BZU	Histidine kinase
CVO_RS08970	ENOG4105BZU	Histidine kinase
CVO_RS08985	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CVO_RS08990	ENOG4105E0A	ABC, transporter
CVO_RS08995	ENOG4105EHG	Permease protein
CVO_RS09000	ENOG4105DDY	UPF0142 protein ycaO
CVO_RS09010	ENOG4108IAB	Phoh family
CVO_RS09015	ENOG4105DCI	Phosphohydrolase
CVO_RS09055	ENOG4105EGS	Mechanosensitive ion channel
CVO_RS09065	ENOG4105VYW	UPF0251 protein
CVO_RS09105	ENOG4108HWY	Beta-lactamase
CVO_RS09110	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CVO_RS09130	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CVO_RS09145	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
CVO_RS09195	ENOG4105C6K	Malic enzyme
CVO_RS09200	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CVO_RS09210	ENOG4105CPC	Aldo Keto reductase
CVO_RS09215	ENOG4108ISG	Major Facilitator
CVO_RS09225	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CVO_RS09260	ENOG4108P3C	
CVO_RS09300	ENOG4105D8G	Major Facilitator superfamily
CVO_RS09330	ENOG4108VPT	UPF0234 protein
CVO_RS09350	ENOG4105C5I	Dehydrogenase
CVO_RS09355	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
CVO_RS09360	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CVO_RS09365	ENOG4105C1J	atp-dependent rna helicase
CVO_RS09375	ENOG4105BZU	Histidine kinase
CVO_RS09380	ENOG4105EB3	Histidine kinase
CVO_RS09390	ENOG4105BZU	Histidine kinase
CVO_RS09400	ENOG4105BZU	Histidine kinase
CVO_RS09415	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CVO_RS09425	ENOG41082DJ	30S ribosomal protein S21
CVO_RS09455	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CVO_RS09460	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CVO_RS09490	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CVO_RS09495	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CVO_RS09505	ENOG4105CI3	gtp-binding protein typa
CVO_RS09515	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CVO_RS09525	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CVO_RS09530	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CVO_RS09535	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CVO_RS09540	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CVO_RS09550	ENOG4105NBK	UPF0345 protein
CVO_RS09560	ENOG4105C0H	protease
CVO_RS09570	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CVO_RS09575	ENOG4107QTF	adenylosuccinate lyase
CVO_RS09580	ENOG4105EI2	Pseudouridine synthase
CVO_RS09590	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CVO_RS09600	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CVO_RS09605	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CVO_RS09620	ENOG4105BZU	Histidine kinase
CVO_RS09625	ENOG4105EUJ	GTP cyclohydrolase i
CVO_RS09630	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CVO_RS09645	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CVO_RS09650	ENOG4107QY8	reductase
CVO_RS09680	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CVO_RS09685	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CVO_RS09690	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CVO_RS09705	ENOG4105DSB	aldose 1-epimerase
CVO_RS09720	ENOG4108S0S	Nucleotidyl transferase
CVO_RS09725	ENOG4105EHM	Aminoglycoside phosphotransferase
CVO_RS09730	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CVO_RS09740	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CVO_RS09745	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CVO_RS09750	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CVO_RS09755	ENOG4105NU9	Preprotein translocase subunit SecG
CVO_RS09795	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CVO_RS09800	ENOG4105HFZ	Membrane