locus-tag	class	description
FJR48_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FJR48_RS00010	COG2199	diguanylate cyclase activity
FJR48_RS00015	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FJR48_RS00025	COG0372	Belongs to the citrate synthase family
FJR48_RS00030	COG3118	belongs to the thioredoxin family
FJR48_RS00040	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FJR48_RS00050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FJR48_RS00055	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FJR48_RS00060	COG0564	pseudouridine synthase activity
FJR48_RS00070	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FJR48_RS00080	COG0107	imidazoleglycerol-phosphate synthase activity
FJR48_RS00090	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FJR48_RS00095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FJR48_RS00105	COG1157	protein secretion by the type III secretion system
FJR48_RS00135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FJR48_RS00140	COG0504	CTP synthase activity
FJR48_RS00150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FJR48_RS00155	COG0233	cytoplasmic translational termination
FJR48_RS00160	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FJR48_RS00170	COG1121	(ABC) transporter
FJR48_RS00175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FJR48_RS00185	COG1058	Belongs to the CinA family
FJR48_RS00185	COG1546	Belongs to the CinA family
FJR48_RS00190	COG0352	thiamine-phosphate diphosphorylase activity
FJR48_RS00195	COG0670	Belongs to the BI1 family
FJR48_RS00230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FJR48_RS00240	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FJR48_RS00245	COG0237	dephospho-CoA kinase activity
FJR48_RS00250	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FJR48_RS00255	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FJR48_RS00260	COG0268	Binds directly to 16S ribosomal RNA
FJR48_RS00265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FJR48_RS00270	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FJR48_RS00275	COG0544	peptidyl-prolyl cis-trans isomerase activity
FJR48_RS00280	COG0740	serine-type endopeptidase activity
FJR48_RS00290	COG0242	peptide deformylase activity
FJR48_RS00300	COG0606	chelatase, subunit chli
FJR48_RS00310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FJR48_RS00315	COG1410	methionine synthase
FJR48_RS00315	COG0646	methionine synthase
FJR48_RS00330	COG0348	domain, Protein
FJR48_RS00335	COG2855	membrane
FJR48_RS00350	COG0328	RNA-DNA hybrid ribonuclease activity
FJR48_RS00355	COG0571	ribonuclease III activity
FJR48_RS00360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FJR48_RS00370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FJR48_RS00375	COG2010	Cytochrome c
FJR48_RS00410	COG0315	cyclic pyranopterin monophosphate synthase activity
FJR48_RS00415	COG0746	molybdenum cofactor guanylyltransferase activity
FJR48_RS00420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FJR48_RS00430	COG1104	cysteine desulfurase activity
FJR48_RS00470	COG1136	(ABC) transporter
FJR48_RS00490	COG1032	radical SAM domain protein
FJR48_RS00505	COG3290	protein histidine kinase activity
FJR48_RS00505	COG0840	transmembrane signaling receptor activity
FJR48_RS00535	COG0840	transmembrane signaling receptor activity
FJR48_RS00540	COG0406	alpha-ribazole phosphatase activity
FJR48_RS00545	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FJR48_RS00560	COG1492	cobalamin metabolic process
FJR48_RS00590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FJR48_RS00620	COG2066	Belongs to the glutaminase family
FJR48_RS00635	COG0575	Belongs to the CDS family
FJR48_RS00640	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FJR48_RS00645	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FJR48_RS00650	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FJR48_RS00670	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FJR48_RS00700	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FJR48_RS00705	COG0148	phosphopyruvate hydratase activity
FJR48_RS00720	COG2239	Acts as a magnesium transporter
FJR48_RS00725	COG1253	flavin adenine dinucleotide binding
FJR48_RS00730	COG0840	transmembrane signaling receptor activity
FJR48_RS00750	COG0367	asparagine synthase
FJR48_RS00770	COG0569	domain protein
FJR48_RS00770	COG0475	glutathione-regulated potassium exporter activity
FJR48_RS00775	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FJR48_RS00785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FJR48_RS00790	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FJR48_RS00795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FJR48_RS00805	COG2604	Protein of unknown function DUF115
FJR48_RS00810	COG1083	cytidylyl-transferase
FJR48_RS00820	COG2089	acid synthase
FJR48_RS00870	COG1032	radical SAM domain protein
FJR48_RS00895	COG3959	Transketolase, thiamine diphosphate binding domain
FJR48_RS00900	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FJR48_RS00910	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FJR48_RS00910	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FJR48_RS00915	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FJR48_RS00920	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FJR48_RS00935	COG0300	oxidoreductase activity
FJR48_RS00960	COG2165	general secretion pathway protein
FJR48_RS00970	COG1459	type II secretion system
FJR48_RS01005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FJR48_RS01020	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FJR48_RS01025	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FJR48_RS01035	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FJR48_RS01040	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FJR48_RS01045	COG0745	RESPONSE REGULATOR receiver
FJR48_RS01055	COG0840	transmembrane signaling receptor activity
FJR48_RS01060	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FJR48_RS01060	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FJR48_RS01065	COG1187	pseudouridine synthase activity
FJR48_RS01070	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FJR48_RS01070	COG0517	IMP dehydrogenase activity
FJR48_RS01080	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FJR48_RS01080	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FJR48_RS01085	COG2022	thiamine diphosphate biosynthetic process
FJR48_RS01090	COG3706	GGDEF domain
FJR48_RS01100	COG0733	neurotransmitter:sodium symporter activity
FJR48_RS01175	COG1196	nuclear chromosome segregation
FJR48_RS01175	COG3264	Mechanosensitive ion channel
FJR48_RS01195	COG0189	ligase activity
FJR48_RS01210	COG3123	guanosine phosphorylase activity
FJR48_RS01220	COG1283	sodium-dependent phosphate transmembrane transporter activity
FJR48_RS01230	COG0281	malic enzyme
FJR48_RS01235	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FJR48_RS01245	COG0314	molybdopterin synthase activity
FJR48_RS01250	COG0303	'Molybdopterin
FJR48_RS01275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FJR48_RS01280	COG2197	response regulator
FJR48_RS01300	COG0051	transcription antitermination factor activity, RNA binding
FJR48_RS01305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FJR48_RS01310	COG0088	Forms part of the polypeptide exit tunnel
FJR48_RS01315	COG0089	rRNA binding
FJR48_RS01320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FJR48_RS01325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FJR48_RS01330	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FJR48_RS01335	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FJR48_RS01340	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FJR48_RS01345	COG0255	Belongs to the universal ribosomal protein uL29 family
FJR48_RS01350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FJR48_RS01355	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FJR48_RS01360	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FJR48_RS01365	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FJR48_RS01370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FJR48_RS01375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FJR48_RS01380	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FJR48_RS01385	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FJR48_RS01390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FJR48_RS01395	COG0200	Binds to the 23S rRNA
FJR48_RS01400	COG0201	protein transport
FJR48_RS01405	COG0024	Methionine aminopeptidase
FJR48_RS01410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FJR48_RS01435	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FJR48_RS01440	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FJR48_RS01445	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FJR48_RS01450	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FJR48_RS01455	COG0202	RNA polymerase activity
FJR48_RS01460	COG0203	ribosomal protein L17
FJR48_RS01480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FJR48_RS01500	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FJR48_RS01505	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FJR48_RS01515	COG0142	geranyltranstransferase activity
FJR48_RS01520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FJR48_RS01545	COG0772	Belongs to the SEDS family
FJR48_RS01550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FJR48_RS01555	COG0586	Pfam SNARE associated Golgi protein
FJR48_RS01565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FJR48_RS01575	COG0052	Belongs to the universal ribosomal protein uS2 family
FJR48_RS01580	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FJR48_RS01585	COG1136	(ABC) transporter
FJR48_RS01600	COG0194	GDP metabolic process
FJR48_RS01605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FJR48_RS01610	COG0018	arginyl-trna synthetase
FJR48_RS01635	COG1522	sequence-specific DNA binding
FJR48_RS01640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FJR48_RS01640	COG1648	precorrin-2 dehydrogenase activity
FJR48_RS01660	COG2151	metal-sulfur cluster biosynthetic enzyme
FJR48_RS01670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FJR48_RS01700	COG3256	nitric oxide reductase
FJR48_RS01715	COG0535	radical SAM domain protein
FJR48_RS01725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FJR48_RS01760	COG1757	Na H antiporter
FJR48_RS01765	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FJR48_RS01770	COG0049	tRNA binding
FJR48_RS01775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FJR48_RS01790	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FJR48_RS01805	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FJR48_RS01810	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FJR48_RS01815	COG0768	penicillin binding
FJR48_RS01830	COG1815	bacterial-type flagellum-dependent cell motility
FJR48_RS01835	COG2165	general secretion pathway protein
FJR48_RS01845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FJR48_RS01855	COG0159	tryptophan synthase activity
FJR48_RS01865	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FJR48_RS01875	COG2255	four-way junction helicase activity
FJR48_RS01880	COG0628	permease
FJR48_RS01895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FJR48_RS01900	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FJR48_RS01905	COG0745	RESPONSE REGULATOR receiver
FJR48_RS01910	COG2264	protein methyltransferase activity
FJR48_RS01915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FJR48_RS01920	COG0688	phosphatidylethanolamine metabolic process
FJR48_RS01930	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FJR48_RS01940	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FJR48_RS01950	COG0560	Phosphoserine phosphatase
FJR48_RS01965	COG0784	Response regulator, receiver
FJR48_RS01965	COG2205	protein histidine kinase activity
FJR48_RS01970	COG0784	Response regulator, receiver
FJR48_RS01970	COG2205	protein histidine kinase activity
FJR48_RS01975	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FJR48_RS01980	COG0629	single-stranded DNA binding
FJR48_RS01985	COG0360	Binds together with S18 to 16S ribosomal RNA
FJR48_RS01990	COG2861	carbohydrate metabolic process
FJR48_RS02000	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FJR48_RS02005	COG0805	protein transport
FJR48_RS02010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FJR48_RS02015	COG0840	transmembrane signaling receptor activity
FJR48_RS02020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FJR48_RS02025	COG2199	diguanylate cyclase activity
FJR48_RS02025	COG2200	EAL domain
FJR48_RS02025	COG3287	FIST C domain
FJR48_RS02030	COG0494	nUDIX hydrolase
FJR48_RS02035	COG0527	aspartate kinase activity
FJR48_RS02050	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FJR48_RS02060	COG0443	Heat shock 70 kDa protein
FJR48_RS02065	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FJR48_RS02070	COG3287	FIST C domain
FJR48_RS02070	COG2200	EAL domain
FJR48_RS02070	COG2199	diguanylate cyclase activity
FJR48_RS02080	COG2199	diguanylate cyclase activity
FJR48_RS02080	COG2200	EAL domain
FJR48_RS02080	COG3287	FIST C domain
FJR48_RS02095	COG0481	GTPase activity
FJR48_RS02100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FJR48_RS02110	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FJR48_RS02120	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FJR48_RS02125	COG0706	membrane insertase activity
FJR48_RS02135	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FJR48_RS02140	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FJR48_RS02145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FJR48_RS02160	COG0642	Histidine kinase
FJR48_RS02165	COG0745	RESPONSE REGULATOR receiver
FJR48_RS02175	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FJR48_RS02180	COG4865	methylaspartate mutase activity
FJR48_RS02190	COG0318	PFAM AMP-dependent synthetase and ligase
FJR48_RS02210	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FJR48_RS02220	COG0557	exoribonuclease II activity
FJR48_RS02235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FJR48_RS02240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FJR48_RS02260	COG2199	diguanylate cyclase activity
FJR48_RS02260	COG2200	EAL domain
FJR48_RS02260	COG3287	FIST C domain
FJR48_RS02265	COG0205	6-phosphofructokinase activity
FJR48_RS02280	COG4771	TonB-dependent receptor
FJR48_RS02285	COG0484	heat shock protein binding
FJR48_RS02300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FJR48_RS02315	COG4774	siderophore transport
FJR48_RS02330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FJR48_RS02340	COG0742	ribosomal rna small subunit methyltransferase
FJR48_RS02350	COG1706	bacterial-type flagellum-dependent cell motility
FJR48_RS02355	COG3951	Flagellar rod assembly protein muramidase FlgJ
FJR48_RS02370	COG4786	Flagellar basal body rod
FJR48_RS02370	COG1256	bacterial-type flagellum assembly
FJR48_RS02375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FJR48_RS02380	COG0628	permease
FJR48_RS02385	COG0512	Glutamine amidotransferase of anthranilate synthase
FJR48_RS02395	COG0045	succinate-CoA ligase (ADP-forming) activity
FJR48_RS02400	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FJR48_RS02430	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FJR48_RS02445	COG2217	Heavy metal translocating P-type atpase
FJR48_RS02490	COG1088	dTDP-glucose 4,6-dehydratase activity
FJR48_RS02495	COG1696	Membrane protein involved in D-alanine export
FJR48_RS02550	COG1216	Glycosyl transferase, family 2
FJR48_RS02560	COG1216	Glycosyl transferase, family 2
FJR48_RS02560	COG0463	Glycosyl transferase, family 2
FJR48_RS02585	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FJR48_RS02585	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FJR48_RS02590	COG0859	PFAM glycosyl transferase family 9
FJR48_RS02600	COG1132	(ABC) transporter
FJR48_RS02625	COG0228	four-way junction DNA binding
FJR48_RS02630	COG1837	Belongs to the UPF0109 family
FJR48_RS02635	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FJR48_RS02640	COG0336	Belongs to the RNA methyltransferase TrmD family
FJR48_RS02645	COG0335	large ribosomal subunit rRNA binding
FJR48_RS02670	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FJR48_RS02680	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FJR48_RS02685	COG2873	o-acetylhomoserine
FJR48_RS02690	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FJR48_RS02695	COG0540	Belongs to the ATCase OTCase family
FJR48_RS02700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FJR48_RS02705	COG4191	Histidine kinase
FJR48_RS02720	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FJR48_RS02725	COG0193	aminoacyl-tRNA hydrolase activity
FJR48_RS02735	COG0019	diaminopimelate decarboxylase activity
FJR48_RS02740	COG0647	UMP catabolic process
FJR48_RS02745	COG0077	Prephenate dehydratase
FJR48_RS02745	COG1605	Chorismate mutase
FJR48_RS02750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FJR48_RS02755	COG1766	The M ring may be actively involved in energy transduction
FJR48_RS02760	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FJR48_RS02770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FJR48_RS02775	COG1496	oxidoreductase activity
FJR48_RS02780	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FJR48_RS02785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FJR48_RS02805	COG4608	Belongs to the ABC transporter superfamily
FJR48_RS02815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FJR48_RS02820	COG0204	Acyl-transferase
FJR48_RS02830	COG0047	phosphoribosylformylglycinamidine synthase activity
FJR48_RS02835	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FJR48_RS02840	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FJR48_RS02845	COG0793	Belongs to the peptidase S41A family
FJR48_RS02860	COG0437	4 iron, 4 sulfur cluster binding
FJR48_RS02875	COG0348	domain, Protein
FJR48_RS02880	COG1131	(ABC) transporter
FJR48_RS02890	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FJR48_RS02900	COG0840	transmembrane signaling receptor activity
FJR48_RS02920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FJR48_RS02935	COG0745	RESPONSE REGULATOR receiver
FJR48_RS02940	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FJR48_RS02945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FJR48_RS02970	COG0210	DNA helicase
FJR48_RS02975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FJR48_RS02980	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FJR48_RS02985	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FJR48_RS02990	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FJR48_RS03005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FJR48_RS03015	COG1519	Transferase
FJR48_RS03020	COG0564	pseudouridine synthase activity
FJR48_RS03025	COG2827	Endonuclease containing a URI domain
FJR48_RS03030	COG1671	Belongs to the UPF0178 family
FJR48_RS03035	COG1451	nucleotide metabolic process
FJR48_RS03045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FJR48_RS03050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FJR48_RS03055	COG2181	nitrate reductase activity
FJR48_RS03055	COG0247	lactate metabolic process
FJR48_RS03075	COG0513	Belongs to the DEAD box helicase family
FJR48_RS03085	COG0564	pseudouridine synthase activity
FJR48_RS03095	COG3287	FIST C domain
FJR48_RS03095	COG2199	diguanylate cyclase activity
FJR48_RS03095	COG2200	EAL domain
FJR48_RS03100	COG1355	regulation of microtubule-based process
FJR48_RS03105	COG0784	Response regulator, receiver
FJR48_RS03105	COG2205	protein histidine kinase activity
FJR48_RS03125	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FJR48_RS03130	COG0459	protein refolding
FJR48_RS03140	COG0784	Response regulator, receiver
FJR48_RS03140	COG3437	response regulator, receiver
FJR48_RS03155	COG0848	biopolymer transport protein
FJR48_RS03160	COG0811	peptide transport
FJR48_RS03165	COG0642	Histidine kinase
FJR48_RS03170	COG0745	RESPONSE REGULATOR receiver
FJR48_RS03175	COG0418	dihydroorotase activity
FJR48_RS03185	COG0308	aminopeptidase N
FJR48_RS03200	COG0784	Response regulator, receiver
FJR48_RS03200	COG5002	protein histidine kinase activity
FJR48_RS03200	COG2205	protein histidine kinase activity
FJR48_RS03210	COG0004	ammonium transporteR
FJR48_RS03220	COG0174	glutamine synthetase
FJR48_RS03245	COG0716	FMN binding
FJR48_RS03250	COG0347	Belongs to the P(II) protein family
FJR48_RS03265	COG0633	Ferredoxin
FJR48_RS03270	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FJR48_RS03280	COG1012	belongs to the aldehyde dehydrogenase family
FJR48_RS03285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJR48_RS03290	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FJR48_RS03305	COG0439	Biotin carboxylase
FJR48_RS03310	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FJR48_RS03350	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FJR48_RS03355	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FJR48_RS03365	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FJR48_RS03370	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FJR48_RS03430	COG0667	Aldo Keto reductase
FJR48_RS03435	COG1053	succinate dehydrogenase
FJR48_RS03465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FJR48_RS03475	COG1119	ATPase activity
FJR48_RS03500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FJR48_RS03535	COG1592	Rubrerythrin
FJR48_RS03540	COG2200	EAL domain
FJR48_RS03540	COG3287	FIST C domain
FJR48_RS03540	COG2199	diguanylate cyclase activity
FJR48_RS03550	COG0659	secondary active sulfate transmembrane transporter activity
FJR48_RS03555	COG0784	Response regulator, receiver
FJR48_RS03555	COG2205	protein histidine kinase activity
FJR48_RS03570	COG0731	radical SAM domain protein
FJR48_RS03575	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FJR48_RS03585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FJR48_RS03590	COG2204	response regulator
FJR48_RS03610	COG0004	ammonium transporteR
FJR48_RS03620	COG0004	ammonium transporteR
FJR48_RS03625	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FJR48_RS03630	COG0489	protein tyrosine kinase activity
FJR48_RS03640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FJR48_RS03645	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FJR48_RS03655	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FJR48_RS03660	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FJR48_RS03665	COG1028	Short-chain dehydrogenase reductase Sdr
FJR48_RS03665	COG3347	Dehydrogenase
FJR48_RS03670	COG1070	Carbohydrate kinase
FJR48_RS03675	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FJR48_RS03680	COG1555	photosystem II stabilization
FJR48_RS03685	COG1216	Glycosyl transferase, family 2
FJR48_RS03695	COG1793	dna ligase
FJR48_RS03700	COG0166	Belongs to the GPI family
FJR48_RS03710	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FJR48_RS03730	COG0175	sulfate reduction
FJR48_RS03735	COG2895	sulfate adenylyltransferase (ATP) activity
FJR48_RS03740	COG0529	Catalyzes the synthesis of activated sulfate
FJR48_RS03745	COG0529	Catalyzes the synthesis of activated sulfate
FJR48_RS03760	COG2192	nodulation
FJR48_RS03810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FJR48_RS03810	COG0519	Catalyzes the synthesis of GMP from XMP
FJR48_RS03825	COG0367	asparagine synthase
FJR48_RS03840	COG1086	Polysaccharide biosynthesis protein
FJR48_RS03855	COG0297	glycogen (starch) synthase activity
FJR48_RS03865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FJR48_RS03870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FJR48_RS03875	COG1086	Polysaccharide biosynthesis protein
FJR48_RS03885	COG0754	glutathionylspermidine amidase activity
FJR48_RS03905	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FJR48_RS03915	COG1077	Cell shape determining protein MreB Mrl
FJR48_RS03920	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FJR48_RS03925	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FJR48_RS03930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FJR48_RS03935	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FJR48_RS03940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FJR48_RS03945	COG5002	protein histidine kinase activity
FJR48_RS03950	COG0745	RESPONSE REGULATOR receiver
FJR48_RS03955	COG0840	transmembrane signaling receptor activity
FJR48_RS03980	COG2176	DNA-directed DNA polymerase activity
FJR48_RS03985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FJR48_RS03990	COG0284	orotidine-5'-phosphate decarboxylase activity
FJR48_RS04090	COG2815	serine threonine protein kinase
FJR48_RS04090	COG0515	serine threonine protein kinase
FJR48_RS04140	COG2197	response regulator
FJR48_RS04150	COG2274	protein secretion by the type I secretion system
FJR48_RS04160	COG2885	chlorophyll binding
FJR48_RS04165	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FJR48_RS04175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FJR48_RS04185	COG0251	oxidation-reduction process
FJR48_RS04195	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FJR48_RS04205	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FJR48_RS04210	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FJR48_RS04230	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FJR48_RS04255	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FJR48_RS04260	COG0298	carbon dioxide binding
FJR48_RS04265	COG0409	Hydrogenase expression formation protein
FJR48_RS04270	COG0588	phosphoglycerate mutase activity
FJR48_RS04275	COG0667	Aldo Keto reductase
FJR48_RS04280	COG0589	response to stress
FJR48_RS04285	COG0309	Hydrogenase expression formation protein (HypE)
FJR48_RS04290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FJR48_RS04290	COG1024	Enoyl-CoA hydratase
FJR48_RS04295	COG0375	protein maturation
FJR48_RS04300	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FJR48_RS04305	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FJR48_RS04310	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FJR48_RS04315	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FJR48_RS04325	COG1192	Involved in chromosome partitioning
FJR48_RS04330	COG1475	DNA binding
FJR48_RS04345	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FJR48_RS04350	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FJR48_RS04355	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FJR48_RS04360	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FJR48_RS04365	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FJR48_RS04370	COG0811	peptide transport
FJR48_RS04375	COG0848	biopolymer transport protein
FJR48_RS04385	COG0823	Involved in the tonB-independent uptake of proteins
FJR48_RS04390	COG2885	chlorophyll binding
FJR48_RS04400	COG1047	Peptidyl-prolyl cis-trans
FJR48_RS04405	COG2204	response regulator
FJR48_RS04410	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FJR48_RS04415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FJR48_RS04415	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FJR48_RS04420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FJR48_RS04425	COG0037	tRNA processing
FJR48_RS04435	COG5002	protein histidine kinase activity
FJR48_RS04435	COG0784	Response regulator, receiver
FJR48_RS04435	COG2198	Histidine kinase
FJR48_RS04445	COG0217	transcriptional regulatory protein
FJR48_RS04450	COG1739	Uncharacterized protein family UPF0029
FJR48_RS04455	COG1459	type II secretion system
FJR48_RS04460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FJR48_RS04480	COG1450	Type ii and iii secretion system protein
FJR48_RS04515	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FJR48_RS04520	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FJR48_RS04525	COG0359	binds to the 23S rRNA
FJR48_RS04535	COG0137	argininosuccinate synthase activity
FJR48_RS04570	COG3287	FIST C domain
FJR48_RS04570	COG2200	EAL domain
FJR48_RS04570	COG2199	diguanylate cyclase activity
FJR48_RS04575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FJR48_RS04590	COG3549	Plasmid maintenance system killer
FJR48_RS04600	COG0196	riboflavin kinase activity
FJR48_RS04605	COG0585	pseudouridine synthase activity
FJR48_RS04620	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FJR48_RS04620	COG2199	diguanylate cyclase activity
FJR48_RS04650	COG0071	Belongs to the small heat shock protein (HSP20) family
FJR48_RS04665	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FJR48_RS04670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FJR48_RS04680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FJR48_RS04685	COG0471	metal ion transport
FJR48_RS04730	COG0501	Belongs to the peptidase M48B family
FJR48_RS04750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FJR48_RS04755	COG0442	prolyl-tRNA aminoacylation
FJR48_RS04770	COG0181	hydroxymethylbilane synthase activity
FJR48_RS04800	COG0840	transmembrane signaling receptor activity
FJR48_RS04815	COG0714	Associated with various cellular activities
FJR48_RS04835	COG2304	oxidoreductase activity
FJR48_RS04845	COG1416	DNA-binding transcription factor activity
FJR48_RS04860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJR48_RS04865	COG0842	Transport permease protein
FJR48_RS04865	COG1129	ABC transporter
FJR48_RS04870	COG0842	Transport permease protein
FJR48_RS04875	COG0287	Prephenate dehydrogenase
FJR48_RS04880	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJR48_RS04890	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FJR48_RS04895	COG0642	Histidine kinase
FJR48_RS04900	COG0745	RESPONSE REGULATOR receiver
FJR48_RS04910	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FJR48_RS04930	COG0157	Belongs to the NadC ModD family
FJR48_RS04955	COG4999	Histidine kinase
FJR48_RS04955	COG3850	Histidine kinase
FJR48_RS04955	COG3437	response regulator, receiver
FJR48_RS04955	COG2205	protein histidine kinase activity
FJR48_RS04965	COG2046	Belongs to the sulfate adenylyltransferase family
FJR48_RS04975	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FJR48_RS04975	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FJR48_RS04980	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FJR48_RS04990	COG0165	Argininosuccinate lyase
FJR48_RS05000	COG0741	lytic transglycosylase activity
FJR48_RS05005	COG0537	adenosine 5'-monophosphoramidase activity
FJR48_RS05010	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FJR48_RS05015	COG0072	phenylalanine-tRNA ligase activity
FJR48_RS05015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJR48_RS05020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FJR48_RS05025	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FJR48_RS05030	COG1185	polyribonucleotide nucleotidyltransferase activity
FJR48_RS05030	COG0539	negative regulation of cytoplasmic translation
FJR48_RS05040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FJR48_RS05045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJR48_RS05075	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FJR48_RS05080	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FJR48_RS05085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FJR48_RS05100	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FJR48_RS05105	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FJR48_RS05110	COG0204	Acyl-transferase
FJR48_RS05115	COG1331	Highly conserved protein containing a thioredoxin domain
FJR48_RS05130	COG4232	protein-disulfide reductase activity
FJR48_RS05140	COG2205	protein histidine kinase activity
FJR48_RS05145	COG1408	metallophosphoesterase
FJR48_RS05160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FJR48_RS05165	COG1472	Belongs to the glycosyl hydrolase 3 family
FJR48_RS05180	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FJR48_RS05200	COG1858	cytochrome C peroxidase
FJR48_RS05215	COG0343	queuine tRNA-ribosyltransferase activity
FJR48_RS05220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FJR48_RS05240	COG0587	DNA-directed DNA polymerase activity
FJR48_RS05245	COG2207	Transcriptional regulator
FJR48_RS05245	COG4753	response regulator
FJR48_RS05255	COG0745	RESPONSE REGULATOR receiver
FJR48_RS05260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FJR48_RS05265	COG1362	aminopeptidase activity
FJR48_RS05270	COG0642	Histidine kinase
FJR48_RS05290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FJR48_RS05290	COG1333	cytochrome c biogenesis protein
FJR48_RS05300	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FJR48_RS05305	COG0546	phosphoglycolate phosphatase activity
FJR48_RS05315	COG5002	protein histidine kinase activity
FJR48_RS05315	COG5001	Diguanylate cyclase
FJR48_RS05320	COG0824	Thioesterase
FJR48_RS05335	COG3287	FIST C domain
FJR48_RS05335	COG2200	EAL domain
FJR48_RS05335	COG2199	diguanylate cyclase activity
FJR48_RS05340	COG2205	protein histidine kinase activity
FJR48_RS05340	COG0784	Response regulator, receiver
FJR48_RS05360	COG3706	GGDEF domain
FJR48_RS05370	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FJR48_RS05375	COG4335	DNA alkylation repair
FJR48_RS05380	COG0741	lytic transglycosylase activity
FJR48_RS05420	COG0419	ATPase involved in DNA repair
FJR48_RS05445	COG1136	(ABC) transporter
FJR48_RS05450	COG0101	tRNA pseudouridine synthase activity
FJR48_RS05465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FJR48_RS05475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FJR48_RS05480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FJR48_RS05490	COG1338	Plays a role in the flagellum-specific transport system
FJR48_RS05495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FJR48_RS05510	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FJR48_RS05520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJR48_RS05525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FJR48_RS05535	COG0521	Mo-molybdopterin cofactor biosynthetic process
FJR48_RS05540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FJR48_RS05555	COG0708	Exodeoxyribonuclease III
FJR48_RS05560	COG2048	Heterodisulfide reductase, subunit B
FJR48_RS05565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FJR48_RS05585	COG0585	pseudouridine synthase activity
FJR48_RS05590	COG0688	phosphatidylethanolamine metabolic process
FJR48_RS05600	COG0012	GTP binding
FJR48_RS05610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FJR48_RS05615	COG3706	GGDEF domain
FJR48_RS05620	COG0133	tryptophan synthase activity
FJR48_RS05625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FJR48_RS05635	COG0698	ribose 5-phosphate isomerase
FJR48_RS05640	COG1994	Peptidase M50
FJR48_RS05645	COG0681	Belongs to the peptidase S26 family
FJR48_RS05650	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FJR48_RS05670	COG0471	metal ion transport
FJR48_RS05680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FJR48_RS05700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FJR48_RS05710	COG4786	Flagellar basal body rod
FJR48_RS05720	COG0066	3-isopropylmalate dehydratase activity
FJR48_RS05725	COG0473	3-isopropylmalate dehydrogenase activity
FJR48_RS05740	COG0788	formyltetrahydrofolate deformylase activity
FJR48_RS05765	COG2171	N-acyltransferase activity
FJR48_RS05795	COG0563	adenylate kinase activity
FJR48_RS05800	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FJR48_RS05805	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FJR48_RS05810	COG0497	DNA recombination
FJR48_RS05815	COG0084	hydrolase, TatD family'
FJR48_RS05825	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FJR48_RS05830	COG0131	Imidazoleglycerol-phosphate dehydratase
FJR48_RS05835	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FJR48_RS05850	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FJR48_RS05855	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FJR48_RS05855	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FJR48_RS05865	COG0768	penicillin binding
FJR48_RS05875	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FJR48_RS05885	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FJR48_RS05895	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FJR48_RS05905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJR48_RS05905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJR48_RS05920	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FJR48_RS05925	COG1763	Mo-molybdopterin cofactor biosynthetic process
FJR48_RS05940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FJR48_RS05960	COG1252	NADH dehydrogenase
FJR48_RS05970	COG1309	transcriptional regulator
FJR48_RS05980	COG1013	pyruvate-flavodoxin oxidoreductase activity
FJR48_RS05985	COG0674	pyruvate-flavodoxin oxidoreductase activity
FJR48_RS05985	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FJR48_RS05995	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FJR48_RS06000	COG0045	succinate-CoA ligase (ADP-forming) activity
FJR48_RS06005	COG0114	fumarate hydratase activity
FJR48_RS06010	COG0039	L-malate dehydrogenase activity
FJR48_RS06035	COG0653	protein targeting
FJR48_RS06045	COG2814	Major facilitator Superfamily
FJR48_RS06050	COG2205	protein histidine kinase activity
FJR48_RS06050	COG0784	Response regulator, receiver
FJR48_RS06065	COG1858	cytochrome C peroxidase
FJR48_RS06070	COG1049	propionate catabolic process, 2-methylcitrate cycle
FJR48_RS06085	COG0330	HflC and HflK could
FJR48_RS06100	COG1674	ftsk spoiiie
FJR48_RS06100	COG1196	nuclear chromosome segregation
FJR48_RS06105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FJR48_RS06130	COG0163	prenyltransferase activity
FJR48_RS06135	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FJR48_RS06140	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FJR48_RS06155	COG0124	histidyl-tRNA synthetase
FJR48_RS06160	COG1166	arginine decarboxylase activity
FJR48_RS06165	COG1045	serine acetyltransferase
FJR48_RS06170	COG0436	Aminotransferase
FJR48_RS06175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FJR48_RS06180	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FJR48_RS06185	COG0440	acetolactate synthase activity
FJR48_RS06190	COG0028	Belongs to the TPP enzyme family
FJR48_RS06200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FJR48_RS06205	COG1832	CoA-binding protein
FJR48_RS06220	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FJR48_RS06225	COG1137	ATPase activity
FJR48_RS06230	COG0802	atpase or kinase
FJR48_RS06235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FJR48_RS06240	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FJR48_RS06245	COG1032	radical SAM domain protein
FJR48_RS06250	COG1022	Amp-dependent synthetase and ligase
FJR48_RS06260	COG0840	transmembrane signaling receptor activity
FJR48_RS06265	COG1227	inorganic diphosphatase activity
FJR48_RS06285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FJR48_RS06290	COG0730	response to heat
FJR48_RS06300	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FJR48_RS06300	COG1776	CheC inhibitor of MCP methylation
FJR48_RS06315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FJR48_RS06330	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FJR48_RS06335	COG0352	thiamine-phosphate diphosphorylase activity
FJR48_RS06340	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FJR48_RS06345	COG0493	'glutamate synthase
FJR48_RS06350	COG0069	glutamate synthase activity
FJR48_RS06350	COG0067	glutamate synthase
FJR48_RS06350	COG0070	glutamate synthase
FJR48_RS06415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FJR48_RS06420	COG3177	Filamentation induced by cAMP protein fic
FJR48_RS06435	COG0732	type I restriction modification DNA specificity domain
FJR48_RS06440	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FJR48_RS06540	COG0582	viral genome integration into host DNA
FJR48_RS06545	COG0842	Transport permease protein
FJR48_RS06550	COG0842	Transport permease protein
FJR48_RS06555	COG1131	(ABC) transporter
FJR48_RS06565	COG0840	transmembrane signaling receptor activity
FJR48_RS06595	COG1181	Belongs to the D-alanine--D-alanine ligase family
FJR48_RS06605	COG0632	four-way junction helicase activity
FJR48_RS06615	COG0728	peptidoglycan biosynthetic process
FJR48_RS06620	COG0215	cysteine-tRNA ligase activity
FJR48_RS06640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJR48_RS06645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FJR48_RS06665	COG0167	dihydroorotate dehydrogenase activity
FJR48_RS06670	COG0612	Peptidase, M16
FJR48_RS06680	COG0563	adenylate kinase activity
FJR48_RS06685	COG0488	(ABC) transporter
FJR48_RS06700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FJR48_RS06710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FJR48_RS06715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FJR48_RS06720	COG1028	Short-chain dehydrogenase reductase Sdr
FJR48_RS06730	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FJR48_RS06735	COG0750	zinc metalloprotease
FJR48_RS06740	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FJR48_RS06760	COG2081	HI0933 family
FJR48_RS06765	COG3706	GGDEF domain
FJR48_RS06770	COG0352	thiamine-phosphate diphosphorylase activity
FJR48_RS06775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FJR48_RS06775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FJR48_RS06800	COG4974	Belongs to the 'phage' integrase family
FJR48_RS06815	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FJR48_RS06825	COG4771	TonB-dependent receptor
FJR48_RS06835	COG0848	biopolymer transport protein
FJR48_RS06855	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FJR48_RS06865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJR48_RS06885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FJR48_RS06900	COG0835	chemotaxis
FJR48_RS06900	COG0784	Response regulator, receiver
FJR48_RS06935	COG0326	Molecular chaperone. Has ATPase activity
FJR48_RS06950	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FJR48_RS06965	COG0488	(ABC) transporter
FJR48_RS06975	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FJR48_RS06995	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FJR48_RS07000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FJR48_RS07015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FJR48_RS07020	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FJR48_RS07035	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FJR48_RS07040	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FJR48_RS07045	COG0484	heat shock protein binding
FJR48_RS07060	COG0811	peptide transport
FJR48_RS07070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FJR48_RS07085	COG0849	cell division
FJR48_RS07090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FJR48_RS07100	COG1136	(ABC) transporter
FJR48_RS07120	COG2890	protein-(glutamine-N5) methyltransferase activity
FJR48_RS07125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FJR48_RS07130	COG1663	tetraacyldisaccharide 4'-kinase activity
FJR48_RS07145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FJR48_RS07150	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FJR48_RS07155	COG0450	alkyl hydroperoxide reductase
FJR48_RS07160	COG2833	Protein of unknown function (DUF455)
FJR48_RS07175	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FJR48_RS07175	COG2050	protein possibly involved in aromatic compounds catabolism
FJR48_RS07180	COG0500	methyltransferase
FJR48_RS07190	COG1418	mRNA catabolic process
FJR48_RS07205	COG0552	protein localization to endoplasmic reticulum
FJR48_RS07210	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FJR48_RS07225	COG2226	methyltransferase
FJR48_RS07230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJR48_RS07230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJR48_RS07235	COG0779	Required for maturation of 30S ribosomal subunits
FJR48_RS07245	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FJR48_RS07255	COG0083	homoserine kinase activity
FJR48_RS07265	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FJR48_RS07280	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FJR48_RS07285	COG1397	ADP-ribosylglycohydrolase
FJR48_RS07315	COG0668	transmembrane transport
FJR48_RS07320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FJR48_RS07325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FJR48_RS07330	COG1053	succinate dehydrogenase
FJR48_RS07340	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR48_RS07345	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR48_RS07350	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR48_RS07350	COG0649	NAD binding
FJR48_RS07355	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FJR48_RS07365	COG1034	ATP synthesis coupled electron transport
FJR48_RS07375	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR48_RS07380	COG0839	Belongs to the complex I subunit 6 family
FJR48_RS07385	COG0713	ATP synthesis coupled electron transport
FJR48_RS07390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FJR48_RS07395	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR48_RS07400	COG1007	ATP synthesis coupled electron transport
FJR48_RS07450	COG1278	Cold shock
FJR48_RS07455	COG1309	transcriptional regulator
FJR48_RS07490	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FJR48_RS07495	COG0857	belongs to the CobB CobQ family
FJR48_RS07495	COG0280	phosphate acetyltransferase
FJR48_RS07500	COG0840	transmembrane signaling receptor activity
FJR48_RS07505	COG2200	EAL domain
FJR48_RS07505	COG2199	diguanylate cyclase activity
FJR48_RS07505	COG3287	FIST C domain
FJR48_RS07515	COG0579	oxidoreductase
FJR48_RS07520	COG0488	(ABC) transporter
FJR48_RS07545	COG0456	acetyltransferase
FJR48_RS07575	COG0616	signal peptide processing
FJR48_RS07580	COG1570	exodeoxyribonuclease VII activity
FJR48_RS07585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FJR48_RS07600	COG1580	Controls the rotational direction of flagella during chemotaxis
FJR48_RS07605	COG1067	ATP-dependent peptidase activity
FJR48_RS07610	COG0736	holo-[acyl-carrier-protein] synthase activity
FJR48_RS07630	COG0356	it plays a direct role in the translocation of protons across the membrane
FJR48_RS07645	COG0275	rRNA processing
FJR48_RS07650	COG2205	protein histidine kinase activity
FJR48_RS07650	COG2198	Histidine kinase
FJR48_RS07650	COG0784	Response regulator, receiver
FJR48_RS07655	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FJR48_RS07660	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FJR48_RS07665	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FJR48_RS07670	COG0697	spore germination
FJR48_RS07675	COG5002	protein histidine kinase activity
FJR48_RS07675	COG5001	Diguanylate cyclase
FJR48_RS07680	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FJR48_RS07700	COG2884	Cell division ATP-binding protein ftsE
FJR48_RS07705	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FJR48_RS07715	COG0564	pseudouridine synthase activity
FJR48_RS07720	COG0772	Belongs to the SEDS family
FJR48_RS07755	COG1546	Belongs to the CinA family
FJR48_RS07755	COG1058	Belongs to the CinA family
FJR48_RS07760	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FJR48_RS07770	COG2329	Antibiotic biosynthesis monooxygenase
FJR48_RS07795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FJR48_RS07805	COG0574	Belongs to the PEP-utilizing enzyme family
FJR48_RS07805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FJR48_RS07815	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FJR48_RS07825	COG0154	amidase activity
FJR48_RS07835	COG1846	Transcriptional regulator
FJR48_RS07840	COG0517	IMP dehydrogenase activity
FJR48_RS07840	COG0516	GMP reductase activity
FJR48_RS07845	COG1714	RDD family
FJR48_RS07860	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FJR48_RS07875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FJR48_RS07885	COG0436	Aminotransferase
FJR48_RS07900	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FJR48_RS07915	COG1193	negative regulation of DNA recombination
FJR48_RS07920	COG2081	HI0933 family
FJR48_RS07925	COG2217	Heavy metal translocating P-type atpase
FJR48_RS07930	COG1846	Transcriptional regulator
FJR48_RS07935	COG2353	YceI-like domain
FJR48_RS07940	COG1704	LemA family
FJR48_RS07965	COG0577	efflux transmembrane transporter activity
FJR48_RS07965	COG1136	(ABC) transporter
FJR48_RS07970	COG0577	efflux transmembrane transporter activity
FJR48_RS07970	COG1136	(ABC) transporter
FJR48_RS07975	COG2203	Gaf domain
FJR48_RS07975	COG4251	negative regulation of phosphorylation
FJR48_RS07975	COG3706	GGDEF domain
FJR48_RS07975	COG5001	Diguanylate cyclase
FJR48_RS07985	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FJR48_RS07990	COG2161	toxin-antitoxin pair type II binding
FJR48_RS08010	COG0437	4 iron, 4 sulfur cluster binding
FJR48_RS08015	COG0348	domain, Protein
FJR48_RS08025	COG3706	GGDEF domain
FJR48_RS08030	COG0525	valine-tRNA ligase activity
FJR48_RS08035	COG0659	secondary active sulfate transmembrane transporter activity
FJR48_RS08045	COG0840	transmembrane signaling receptor activity
FJR48_RS08055	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FJR48_RS08060	COG1610	YqeY-like protein
FJR48_RS08065	COG0134	indole-3-glycerol-phosphate synthase activity
FJR48_RS08075	COG0727	PFAM Uncharacterised protein family (UPF0153)
FJR48_RS08080	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FJR48_RS08085	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FJR48_RS08090	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FJR48_RS08095	COG2201	protein-glutamate methylesterase activity
FJR48_RS08100	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FJR48_RS08110	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FJR48_RS08115	COG2404	hydrolase activity, acting on ester bonds
FJR48_RS08135	COG0860	N-Acetylmuramoyl-L-alanine amidase
FJR48_RS08145	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FJR48_RS08150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FJR48_RS08160	COG0528	UMP kinase activity
FJR48_RS08165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FJR48_RS08175	COG0243	molybdopterin cofactor binding
FJR48_RS08180	COG0437	4 iron, 4 sulfur cluster binding
FJR48_RS08185	COG2223	nitrite transmembrane transporter activity
FJR48_RS08195	COG0243	molybdopterin cofactor binding
FJR48_RS08200	COG1116	anion transmembrane transporter activity
FJR48_RS08200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FJR48_RS08210	COG1116	anion transmembrane transporter activity
FJR48_RS08220	COG0515	serine threonine protein kinase
FJR48_RS08225	COG0339	signal peptide processing
FJR48_RS08235	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FJR48_RS08260	COG0482	sulfurtransferase activity
FJR48_RS08265	COG1611	Belongs to the LOG family
FJR48_RS08270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FJR48_RS08280	COG1191	sigma factor activity
FJR48_RS08290	COG0455	bacterial-type flagellum organization
FJR48_RS08295	COG1419	protein localization to endoplasmic reticulum
FJR48_RS08300	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FJR48_RS08305	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FJR48_RS08310	COG0402	S-adenosylhomocysteine deaminase activity
FJR48_RS08315	COG5001	Diguanylate cyclase
FJR48_RS08315	COG2203	Gaf domain
FJR48_RS08315	COG4251	negative regulation of phosphorylation
FJR48_RS08315	COG3706	GGDEF domain
FJR48_RS08330	COG0243	molybdopterin cofactor binding
FJR48_RS08335	COG0437	4 iron, 4 sulfur cluster binding
FJR48_RS08340	COG0348	domain, Protein
FJR48_RS08380	COG0006	proline dipeptidase activity
FJR48_RS08395	COG1127	ABC transporter
FJR48_RS08400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FJR48_RS08405	COG0835	chemotaxis
FJR48_RS08410	COG0784	Response regulator, receiver
FJR48_RS08410	COG2198	Histidine kinase
FJR48_RS08410	COG0643	Histidine kinase
FJR48_RS08415	COG0835	chemotaxis
FJR48_RS08415	COG0784	Response regulator, receiver
FJR48_RS08425	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FJR48_RS08445	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FJR48_RS08450	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FJR48_RS08470	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FJR48_RS08475	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FJR48_RS08485	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FJR48_RS08490	COG2205	protein histidine kinase activity
FJR48_RS08495	COG0745	RESPONSE REGULATOR receiver
FJR48_RS08505	COG1692	metallophosphoesterase
FJR48_RS08520	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FJR48_RS08530	COG0739	heme binding
FJR48_RS08535	COG0285	dihydrofolate synthase activity
FJR48_RS08555	COG0495	leucyl-tRNA aminoacylation
FJR48_RS08565	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FJR48_RS08570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FJR48_RS08575	COG1862	Preprotein translocase
FJR48_RS08580	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FJR48_RS08585	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FJR48_RS08590	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FJR48_RS08670	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FJR48_RS08675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FJR48_RS08680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FJR48_RS08695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FJR48_RS08700	COG0135	phosphoribosylanthranilate isomerase activity
FJR48_RS08705	COG2176	DNA-directed DNA polymerase activity
FJR48_RS08710	COG0825	malonyl-CoA metabolic process
FJR48_RS08715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJR48_RS08720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJR48_RS08730	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FJR48_RS08735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FJR48_RS08740	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FJR48_RS08745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FJR48_RS08750	COG2860	membrane
FJR48_RS08765	COG0778	Nitroreductase
FJR48_RS08775	COG3706	GGDEF domain
FJR48_RS08790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FJR48_RS08800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FJR48_RS08810	COG3706	GGDEF domain
FJR48_RS08820	COG0542	response to heat
FJR48_RS08825	COG0642	Histidine kinase
FJR48_RS08830	COG0745	RESPONSE REGULATOR receiver
FJR48_RS08850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FJR48_RS08855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FJR48_RS08865	COG2226	methyltransferase
FJR48_RS08900	COG0776	regulation of translation
FJR48_RS08910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FJR48_RS08915	COG0306	phosphate transporter
FJR48_RS08950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FJR48_RS08975	COG4263	nitrous-oxide reductase activity
FJR48_RS08980	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FJR48_RS08980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FJR48_RS08995	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FJR48_RS09040	COG0582	viral genome integration into host DNA
FJR48_RS09050	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FJR48_RS09055	COG1185	polyribonucleotide nucleotidyltransferase activity
FJR48_RS09080	COG5002	protein histidine kinase activity
FJR48_RS09085	COG2204	response regulator
FJR48_RS09090	COG0840	transmembrane signaling receptor activity
FJR48_RS09100	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FJR48_RS09100	COG0519	Catalyzes the synthesis of GMP from XMP
FJR48_RS09105	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FJR48_RS09120	COG0322	excinuclease ABC activity
FJR48_RS09140	COG0745	RESPONSE REGULATOR receiver
FJR48_RS09150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FJR48_RS09155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJR48_RS09160	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FJR48_RS09185	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FJR48_RS09190	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FJR48_RS09195	COG0612	Peptidase, M16
FJR48_RS09200	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FJR48_RS09215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FJR48_RS09220	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FJR48_RS09235	COG0133	tryptophan synthase activity
FJR48_RS09270	COG1160	GTP binding
FJR48_RS09275	COG1981	membrane
FJR48_RS09300	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FJR48_RS09305	COG0113	porphobilinogen synthase activity
FJR48_RS09310	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FJR48_RS09325	COG5002	protein histidine kinase activity
FJR48_RS09340	COG1368	sulfuric ester hydrolase activity
FJR48_RS09345	COG0357	Ribosomal RNA small subunit methyltransferase G
FJR48_RS09360	COG5001	Diguanylate cyclase
FJR48_RS09360	COG5002	protein histidine kinase activity
FJR48_RS09365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FJR48_RS09370	COG2957	Belongs to the agmatine deiminase family
FJR48_RS09380	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FJR48_RS09385	COG0305	Participates in initiation and elongation during chromosome replication
FJR48_RS09405	COG1881	PFAM PEBP family protein
FJR48_RS09410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FJR48_RS09440	COG1295	ribonuclease BN
FJR48_RS09440	COG1959	2 iron, 2 sulfur cluster binding
FJR48_RS09445	COG0277	FAD linked oxidase domain protein
FJR48_RS09455	COG0739	heme binding
FJR48_RS09455	COG0741	lytic transglycosylase activity
FJR48_RS09455	COG1196	nuclear chromosome segregation
FJR48_RS09465	COG0784	Response regulator, receiver
FJR48_RS09465	COG3437	response regulator, receiver
FJR48_RS09470	COG0428	transporter
FJR48_RS09475	COG2193	ferroxidase activity
FJR48_RS09485	COG1902	pentaerythritol trinitrate reductase activity
FJR48_RS09510	COG1017	nitric oxide dioxygenase activity
FJR48_RS09520	COG0556	nucleotide-excision repair
FJR48_RS09545	COG2081	HI0933 family
FJR48_RS09550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJR48_RS09555	COG0037	tRNA processing
FJR48_RS09575	COG4974	Belongs to the 'phage' integrase family
FJR48_RS09585	COG2121	Domain of unknown function (DUF374)
FJR48_RS09590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJR48_RS09600	COG0195	Participates in both transcription termination and antitermination
FJR48_RS09615	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FJR48_RS09620	COG0149	triose-phosphate isomerase activity
FJR48_RS09625	COG0126	phosphoglycerate kinase activity
FJR48_RS09635	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FJR48_RS09640	COG0799	negative regulation of ribosome biogenesis
FJR48_RS09650	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FJR48_RS09655	COG0642	Histidine kinase
FJR48_RS09660	COG0745	RESPONSE REGULATOR receiver
FJR48_RS09665	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FJR48_RS09685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FJR48_RS09695	COG4771	TonB-dependent receptor
FJR48_RS09720	COG1429	ligase activity, forming nitrogen-metal bonds
FJR48_RS09725	COG4771	TonB-dependent receptor
FJR48_RS09730	COG4206	TonB-dependent receptor
FJR48_RS09745	COG1528	Iron-storage protein
FJR48_RS09760	COG0716	FMN binding
FJR48_RS09765	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FJR48_RS09790	COG0848	biopolymer transport protein
FJR48_RS09795	COG0811	peptide transport
FJR48_RS09810	COG1858	cytochrome C peroxidase
FJR48_RS09860	COG1183	phosphatidylcholine synthase activity
FJR48_RS09870	COG0745	RESPONSE REGULATOR receiver
FJR48_RS09875	COG0783	Belongs to the Dps family
FJR48_RS09905	COG1322	Protein conserved in bacteria
FJR48_RS09915	COG0513	Belongs to the DEAD box helicase family
FJR48_RS09925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FJR48_RS09930	COG0416	fatty acid biosynthetic process
FJR48_RS09935	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FJR48_RS09945	COG0105	UTP biosynthetic process
FJR48_RS09955	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FJR48_RS09960	COG0450	alkyl hydroperoxide reductase
FJR48_RS09970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FJR48_RS09975	COG3864	Putative metallopeptidase domain
FJR48_RS09990	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FJR48_RS09995	COG0840	transmembrane signaling receptor activity
FJR48_RS10000	COG0840	transmembrane signaling receptor activity
FJR48_RS10010	COG4948	Mandelate Racemase Muconate Lactonizing
FJR48_RS10035	COG1254	Belongs to the acylphosphatase family
FJR48_RS10040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FJR48_RS10045	COG0085	RNA polymerase activity
FJR48_RS10055	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FJR48_RS10060	COG0081	regulation of translation
FJR48_RS10065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FJR48_RS10070	COG0250	Participates in transcription elongation, termination and antitermination
FJR48_RS10085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FJR48_RS10090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FJR48_RS10115	COG3022	response to hydroperoxide
FJR48_RS10130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FJR48_RS10140	COG0300	oxidoreductase activity
FJR48_RS10145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FJR48_RS10180	COG0840	transmembrane signaling receptor activity
FJR48_RS10185	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FJR48_RS10220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FJR48_RS10235	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FJR48_RS10245	COG0531	amino acid
FJR48_RS10250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FJR48_RS10255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FJR48_RS10260	COG0752	glycyl-tRNA synthetase alpha subunit
FJR48_RS10285	COG5002	protein histidine kinase activity
FJR48_RS10285	COG0784	Response regulator, receiver
FJR48_RS10285	COG2205	protein histidine kinase activity
FJR48_RS10290	COG3437	response regulator, receiver
FJR48_RS10290	COG0784	Response regulator, receiver
FJR48_RS10310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FJR48_RS10315	COG0826	peptidase U32
FJR48_RS10325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FJR48_RS10340	COG3118	belongs to the thioredoxin family
FJR48_RS10350	COG0492	ferredoxin-NADP+ reductase activity
FJR48_RS10360	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FJR48_RS10370	COG1007	ATP synthesis coupled electron transport
FJR48_RS10380	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FJR48_RS10385	COG0713	ATP synthesis coupled electron transport
FJR48_RS10390	COG0839	Belongs to the complex I subunit 6 family
FJR48_RS10395	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR48_RS10400	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FJR48_RS10405	COG1034	ATP synthesis coupled electron transport
FJR48_RS10425	COG0649	NAD binding
FJR48_RS10430	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR48_RS10435	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR48_RS10440	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR48_RS10445	COG1222	aaa ATPase
FJR48_RS10455	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FJR48_RS10465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FJR48_RS10480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FJR48_RS10485	COG1242	4 iron, 4 sulfur cluster binding
FJR48_RS10490	COG0745	RESPONSE REGULATOR receiver
FJR48_RS10495	COG0642	Histidine kinase
FJR48_RS10515	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FJR48_RS10540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FJR48_RS10540	COG0140	phosphoribosyl-ATP diphosphatase activity
FJR48_RS10545	COG0330	HflC and HflK could
FJR48_RS10565	COG0811	peptide transport
FJR48_RS10575	COG0848	biopolymer transport protein
FJR48_RS10595	COG0745	RESPONSE REGULATOR receiver
FJR48_RS10600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FJR48_RS10605	COG2200	EAL domain
FJR48_RS10625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FJR48_RS10635	COG2207	Transcriptional regulator
FJR48_RS10655	COG1028	Short-chain dehydrogenase reductase Sdr
FJR48_RS10675	COG1064	alcohol dehydrogenase
FJR48_RS10695	COG0573	inorganic phosphate transmembrane transporter activity
FJR48_RS10700	COG0581	inorganic phosphate transmembrane transporter activity
FJR48_RS10705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FJR48_RS10715	COG3706	GGDEF domain
FJR48_RS10725	COG0174	glutamine synthetase
FJR48_RS10730	COG0784	Response regulator, receiver
FJR48_RS10730	COG2205	protein histidine kinase activity
FJR48_RS10735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FJR48_RS10745	COG0642	Histidine kinase
FJR48_RS10810	COG1131	(ABC) transporter
FJR48_RS10835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJR48_RS10845	COG2986	histidine ammonia-lyase
FJR48_RS10855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJR48_RS10860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJR48_RS10890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJR48_RS10910	COG2197	response regulator
FJR48_RS10915	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FJR48_RS10920	COG0444	Belongs to the ABC transporter superfamily
FJR48_RS10950	COG0156	8-amino-7-oxononanoate synthase activity
FJR48_RS10960	COG3706	GGDEF domain
FJR48_RS10960	COG5001	Diguanylate cyclase
FJR48_RS10960	COG4251	negative regulation of phosphorylation
FJR48_RS10960	COG2203	Gaf domain
FJR48_RS10970	COG1278	Cold shock
FJR48_RS10975	COG0424	maF-like protein
FJR48_RS10985	COG2205	protein histidine kinase activity
FJR48_RS10985	COG0784	Response regulator, receiver
FJR48_RS10995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FJR48_RS11015	COG1012	belongs to the aldehyde dehydrogenase family
FJR48_RS11030	COG0792	nuclease activity
FJR48_RS11035	COG3383	formate dehydrogenase (NAD+) activity
FJR48_RS11040	COG0460	homoserine dehydrogenase
FJR48_RS11045	COG0436	Aminotransferase
FJR48_RS11060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FJR48_RS11065	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FJR48_RS11070	COG0254	rRNA binding
FJR48_RS11075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FJR48_RS11085	COG0303	'Molybdopterin
FJR48_RS11090	COG0720	synthase
FJR48_RS11095	COG0602	queuosine metabolic process
FJR48_RS11100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FJR48_RS11130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FJR48_RS11150	COG0445	tRNA wobble uridine modification
FJR48_RS11170	COG3706	GGDEF domain
FJR48_RS11200	COG1854	S-ribosylhomocysteine lyase activity
FJR48_RS11205	COG1013	pyruvate-flavodoxin oxidoreductase activity
FJR48_RS11210	COG0674	pyruvate-flavodoxin oxidoreductase activity
FJR48_RS11215	COG1144	Oxidoreductase
FJR48_RS11220	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FJR48_RS11225	COG0546	phosphoglycolate phosphatase activity
FJR48_RS11240	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FJR48_RS11245	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FJR48_RS11250	COG1280	lysine exporter protein (LysE YggA)
FJR48_RS11280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FJR48_RS11280	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FJR48_RS11315	COG3278	Belongs to the heme-copper respiratory oxidase family
FJR48_RS11320	COG0505	Belongs to the CarA family
FJR48_RS11335	COG3706	GGDEF domain
FJR48_RS11350	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FJR48_RS11355	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FJR48_RS11360	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FJR48_RS11365	COG1968	undecaprenyl-diphosphatase activity
FJR48_RS11370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FJR48_RS11375	COG2814	Major facilitator Superfamily
FJR48_RS11385	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FJR48_RS11415	COG0129	dihydroxy-acid dehydratase activity
FJR48_RS11450	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
FJR48_RS11465	COG3001	Fructosamine kinase
FJR48_RS11485	COG1132	(ABC) transporter
FJR48_RS11490	COG2116	formate transmembrane transporter activity
FJR48_RS11520	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJR48_RS11520	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJR48_RS11535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FJR48_RS11560	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJR48_RS11580	COG2259	Doxx family
FJR48_RS11590	COG0745	RESPONSE REGULATOR receiver
FJR48_RS11595	COG0642	Histidine kinase
FJR48_RS11600	COG0513	Belongs to the DEAD box helicase family
FJR48_RS11605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FJR48_RS11645	COG1666	GTP binding
FJR48_RS11655	COG1053	succinate dehydrogenase
FJR48_RS11670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FJR48_RS11675	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FJR48_RS11685	COG1749	Flagellar hook protein flgE
FJR48_RS11695	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FJR48_RS11715	COG0482	sulfurtransferase activity
FJR48_RS11725	COG0358	DNA primase activity
FJR48_RS11730	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FJR48_RS11750	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FJR48_RS11805	COG3179	chitinase
FJR48_RS11820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FJR48_RS11845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FJR48_RS11855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FJR48_RS11855	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FJR48_RS11860	COG1217	gtp-binding protein TYPA
FJR48_RS11865	COG0617	tRNA 3'-terminal CCA addition
FJR48_RS11875	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FJR48_RS11880	COG5001	Diguanylate cyclase
FJR48_RS11885	COG0187	DNA topoisomerase II activity
FJR48_RS11890	COG0592	DNA-directed DNA polymerase activity
FJR48_RS11900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJR48_RS11905	COG2121	Domain of unknown function (DUF374)
FJR48_RS11940	COG0037	tRNA processing
FJR48_RS11945	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJR48_RS11950	COG2081	HI0933 family
FJR48_RS11965	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FJR48_RS11975	COG0556	nucleotide-excision repair
FJR48_RS12010	COG1902	pentaerythritol trinitrate reductase activity
FJR48_RS12040	COG1017	nitric oxide dioxygenase activity
FJR48_RS12050	COG0556	nucleotide-excision repair
FJR48_RS12060	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FJR48_RS12075	COG2081	HI0933 family
FJR48_RS12080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJR48_RS12105	COG4974	Belongs to the 'phage' integrase family
FJR48_RS12115	COG2121	Domain of unknown function (DUF374)
FJR48_RS12120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine