locus-tag	class	description
FJR45_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FJR45_RS00010	COG0592	DNA-directed DNA polymerase activity
FJR45_RS00015	COG0187	DNA topoisomerase II activity
FJR45_RS00030	COG1217	gtp-binding protein TYPA
FJR45_RS00035	COG0429	hydrolase of the alpha beta-hydrolase fold
FJR45_RS00040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FJR45_RS00055	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FJR45_RS00085	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FJR45_RS00095	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FJR45_RS00100	COG0640	Transcriptional regulator
FJR45_RS00105	COG2010	Cytochrome c
FJR45_RS00145	COG0745	RESPONSE REGULATOR receiver
FJR45_RS00150	COG0642	Histidine kinase
FJR45_RS00165	COG0358	DNA primase activity
FJR45_RS00185	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FJR45_RS00195	COG1749	Flagellar hook protein flgE
FJR45_RS00200	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FJR45_RS00205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FJR45_RS00210	COG1053	succinate dehydrogenase
FJR45_RS00220	COG2201	protein-glutamate methylesterase activity
FJR45_RS00230	COG4999	Histidine kinase
FJR45_RS00230	COG3437	response regulator, receiver
FJR45_RS00230	COG2205	protein histidine kinase activity
FJR45_RS00230	COG3850	Histidine kinase
FJR45_RS00235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FJR45_RS00240	COG1666	GTP binding
FJR45_RS00250	COG0569	domain protein
FJR45_RS00255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FJR45_RS00260	COG0038	chloride channel
FJR45_RS00280	COG0406	alpha-ribazole phosphatase activity
FJR45_RS00290	COG0582	viral genome integration into host DNA
FJR45_RS00450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FJR45_RS00460	COG1032	radical SAM domain protein
FJR45_RS00470	COG0840	transmembrane signaling receptor activity
FJR45_RS00475	COG0840	transmembrane signaling receptor activity
FJR45_RS00505	COG2205	protein histidine kinase activity
FJR45_RS00505	COG3437	response regulator, receiver
FJR45_RS00505	COG3850	Histidine kinase
FJR45_RS00505	COG4999	Histidine kinase
FJR45_RS00560	COG0840	transmembrane signaling receptor activity
FJR45_RS00565	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FJR45_RS00600	COG0473	3-isopropylmalate dehydrogenase activity
FJR45_RS00610	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FJR45_RS00615	COG1492	cobalamin metabolic process
FJR45_RS00625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FJR45_RS00650	COG2801	Transposase and inactivated derivatives
FJR45_RS00725	COG1797	cobyrinic acid a,c-diamide synthase activity
FJR45_RS00785	COG0575	Belongs to the CDS family
FJR45_RS00790	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FJR45_RS00795	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FJR45_RS00800	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FJR45_RS00810	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FJR45_RS00820	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FJR45_RS00830	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FJR45_RS00835	COG0148	phosphopyruvate hydratase activity
FJR45_RS00855	COG2239	Acts as a magnesium transporter
FJR45_RS00860	COG1253	flavin adenine dinucleotide binding
FJR45_RS00865	COG0840	transmembrane signaling receptor activity
FJR45_RS00895	COG1301	dicarboxylic acid transport
FJR45_RS00915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FJR45_RS00920	COG0492	ferredoxin-NADP+ reductase activity
FJR45_RS00925	COG0475	glutathione-regulated potassium exporter activity
FJR45_RS00925	COG0569	domain protein
FJR45_RS00930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FJR45_RS00940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FJR45_RS00965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FJR45_RS00980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FJR45_RS00990	COG2089	acid synthase
FJR45_RS00995	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FJR45_RS01000	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FJR45_RS01005	COG1083	cytidylyl-transferase
FJR45_RS01010	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FJR45_RS01025	COG4221	oxidoreductase activity
FJR45_RS01030	COG0561	phosphatase activity
FJR45_RS01045	COG1017	nitric oxide dioxygenase activity
FJR45_RS01080	COG0733	neurotransmitter:sodium symporter activity
FJR45_RS01090	COG2022	thiamine diphosphate biosynthetic process
FJR45_RS01095	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FJR45_RS01095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FJR45_RS01105	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FJR45_RS01105	COG0517	IMP dehydrogenase activity
FJR45_RS01110	COG1187	pseudouridine synthase activity
FJR45_RS01115	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FJR45_RS01125	COG0840	transmembrane signaling receptor activity
FJR45_RS01135	COG0281	malic enzyme
FJR45_RS01140	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FJR45_RS01150	COG0314	molybdopterin synthase activity
FJR45_RS01155	COG0303	'Molybdopterin
FJR45_RS01180	COG0166	Belongs to the GPI family
FJR45_RS01215	COG0166	Belongs to the GPI family
FJR45_RS01225	COG0529	Catalyzes the synthesis of activated sulfate
FJR45_RS01230	COG0529	Catalyzes the synthesis of activated sulfate
FJR45_RS01235	COG2895	sulfate adenylyltransferase (ATP) activity
FJR45_RS01250	COG0175	sulfate reduction
FJR45_RS01265	COG3335	DDE superfamily endonuclease
FJR45_RS01275	COG3335	DDE superfamily endonuclease
FJR45_RS01290	COG2026	Addiction module toxin, RelE StbE family
FJR45_RS01350	COG2895	sulfate adenylyltransferase (ATP) activity
FJR45_RS01355	COG0175	sulfate reduction
FJR45_RS01375	COG2026	Addiction module toxin, RelE StbE family
FJR45_RS01415	COG1216	Glycosyl transferase, family 2
FJR45_RS01415	COG0438	transferase activity, transferring glycosyl groups
FJR45_RS01470	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FJR45_RS01485	COG0051	transcription antitermination factor activity, RNA binding
FJR45_RS01490	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FJR45_RS01495	COG0088	Forms part of the polypeptide exit tunnel
FJR45_RS01500	COG0089	rRNA binding
FJR45_RS01505	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FJR45_RS01510	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FJR45_RS01515	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FJR45_RS01520	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FJR45_RS01525	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FJR45_RS01530	COG0255	Belongs to the universal ribosomal protein uL29 family
FJR45_RS01535	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FJR45_RS01540	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FJR45_RS01545	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FJR45_RS01550	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FJR45_RS01555	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FJR45_RS01560	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FJR45_RS01565	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FJR45_RS01570	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FJR45_RS01575	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FJR45_RS01580	COG0200	Binds to the 23S rRNA
FJR45_RS01585	COG0201	protein transport
FJR45_RS01590	COG0024	Methionine aminopeptidase
FJR45_RS01595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FJR45_RS01650	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FJR45_RS01655	COG0709	Synthesizes selenophosphate from selenide and ATP
FJR45_RS01665	COG0778	Nitroreductase
FJR45_RS01695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FJR45_RS01695	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FJR45_RS01700	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FJR45_RS01705	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FJR45_RS01710	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FJR45_RS01715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FJR45_RS01720	COG0202	RNA polymerase activity
FJR45_RS01725	COG0203	ribosomal protein L17
FJR45_RS01745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FJR45_RS01755	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FJR45_RS01760	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FJR45_RS01770	COG0142	geranyltranstransferase activity
FJR45_RS01775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FJR45_RS01780	COG4251	negative regulation of phosphorylation
FJR45_RS01780	COG5001	Diguanylate cyclase
FJR45_RS01780	COG3706	GGDEF domain
FJR45_RS01780	COG2203	Gaf domain
FJR45_RS01795	COG4251	negative regulation of phosphorylation
FJR45_RS01795	COG3706	GGDEF domain
FJR45_RS01795	COG2203	Gaf domain
FJR45_RS01795	COG5001	Diguanylate cyclase
FJR45_RS01800	COG5001	Diguanylate cyclase
FJR45_RS01800	COG3300	MHYT domain
FJR45_RS01820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FJR45_RS01835	COG0840	transmembrane signaling receptor activity
FJR45_RS01840	COG0840	transmembrane signaling receptor activity
FJR45_RS01845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FJR45_RS01850	COG3022	response to hydroperoxide
FJR45_RS01880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FJR45_RS01885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FJR45_RS01900	COG0250	Participates in transcription elongation, termination and antitermination
FJR45_RS01905	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FJR45_RS01910	COG0081	regulation of translation
FJR45_RS01915	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FJR45_RS01920	COG0222	ribosome binding
FJR45_RS01925	COG0085	RNA polymerase activity
FJR45_RS01930	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FJR45_RS01935	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FJR45_RS01940	COG0049	tRNA binding
FJR45_RS01945	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FJR45_RS01965	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FJR45_RS01970	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FJR45_RS01990	COG1815	bacterial-type flagellum-dependent cell motility
FJR45_RS02015	COG4969	Belongs to the N-Me-Phe pilin family
FJR45_RS02020	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FJR45_RS02025	COG0494	nUDIX hydrolase
FJR45_RS02030	COG0739	heme binding
FJR45_RS02040	COG0277	FAD linked oxidase domain protein
FJR45_RS02045	COG1295	ribonuclease BN
FJR45_RS02075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FJR45_RS02095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FJR45_RS02110	COG0357	Ribosomal RNA small subunit methyltransferase G
FJR45_RS02125	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FJR45_RS02130	COG0113	porphobilinogen synthase activity
FJR45_RS02135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FJR45_RS02140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FJR45_RS02145	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FJR45_RS02170	COG1981	membrane
FJR45_RS02175	COG1160	GTP binding
FJR45_RS02210	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FJR45_RS02215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FJR45_RS02230	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FJR45_RS02235	COG0612	Peptidase, M16
FJR45_RS02250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FJR45_RS02265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FJR45_RS02275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FJR45_RS02285	COG2205	protein histidine kinase activity
FJR45_RS02285	COG0784	Response regulator, receiver
FJR45_RS02305	COG0772	Belongs to the SEDS family
FJR45_RS02310	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FJR45_RS02315	COG0586	Pfam SNARE associated Golgi protein
FJR45_RS02325	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FJR45_RS02340	COG2199	diguanylate cyclase activity
FJR45_RS02340	COG3287	FIST C domain
FJR45_RS02340	COG2200	EAL domain
FJR45_RS02350	COG0052	Belongs to the universal ribosomal protein uS2 family
FJR45_RS02355	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FJR45_RS02360	COG1252	NADH dehydrogenase
FJR45_RS02365	COG1136	(ABC) transporter
FJR45_RS02380	COG0194	GDP metabolic process
FJR45_RS02385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FJR45_RS02390	COG0018	arginyl-trna synthetase
FJR45_RS02405	COG1757	Na H antiporter
FJR45_RS02450	COG0544	peptidyl-prolyl cis-trans isomerase activity
FJR45_RS02460	COG0674	pyruvate-flavodoxin oxidoreductase activity
FJR45_RS02460	COG1013	pyruvate-flavodoxin oxidoreductase activity
FJR45_RS02460	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FJR45_RS02460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FJR45_RS02465	COG0674	pyruvate-flavodoxin oxidoreductase activity
FJR45_RS02485	COG1013	pyruvate-flavodoxin oxidoreductase activity
FJR45_RS02505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FJR45_RS02515	COG3002	Belongs to the UPF0753 family
FJR45_RS02530	COG4948	Mandelate Racemase Muconate Lactonizing
FJR45_RS02540	COG4948	Mandelate Racemase Muconate Lactonizing
FJR45_RS02545	COG3706	GGDEF domain
FJR45_RS02565	COG3864	Putative metallopeptidase domain
FJR45_RS02575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FJR45_RS02585	COG3706	GGDEF domain
FJR45_RS02595	COG0450	alkyl hydroperoxide reductase
FJR45_RS02605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FJR45_RS02615	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FJR45_RS02625	COG2165	general secretion pathway protein
FJR45_RS02635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FJR45_RS02710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FJR45_RS02720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FJR45_RS02720	COG0574	Belongs to the PEP-utilizing enzyme family
FJR45_RS02725	COG1830	Aldolase
FJR45_RS02735	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FJR45_RS02740	COG0508	dehydrogenase complex catalyzes the overall conversion of
FJR45_RS02740	COG0022	dehydrogenase e1 component
FJR45_RS02745	COG0508	dehydrogenase complex catalyzes the overall conversion of
FJR45_RS02750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FJR45_RS02755	COG0321	lipoyl(octanoyl) transferase activity
FJR45_RS02760	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FJR45_RS02765	COG0588	phosphoglycerate mutase activity
FJR45_RS02775	COG3228	Belongs to the MtfA family
FJR45_RS02780	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FJR45_RS02790	COG0105	UTP biosynthetic process
FJR45_RS02800	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FJR45_RS02805	COG0416	fatty acid biosynthetic process
FJR45_RS02810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FJR45_RS02820	COG0513	Belongs to the DEAD box helicase family
FJR45_RS02825	COG1322	Protein conserved in bacteria
FJR45_RS02835	COG2259	Doxx family
FJR45_RS02840	COG1183	phosphatidylcholine synthase activity
FJR45_RS02850	COG1918	ferrous iron import across plasma membrane
FJR45_RS02855	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FJR45_RS02860	COG0745	RESPONSE REGULATOR receiver
FJR45_RS02865	COG0642	Histidine kinase
FJR45_RS02870	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FJR45_RS02880	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FJR45_RS02890	COG0126	phosphoglycerate kinase activity
FJR45_RS02895	COG0149	triose-phosphate isomerase activity
FJR45_RS02900	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FJR45_RS02925	COG0601	transmembrane transport
FJR45_RS02930	COG0195	Participates in both transcription termination and antitermination
FJR45_RS02940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJR45_RS02945	COG2121	Domain of unknown function (DUF374)
FJR45_RS02955	COG4974	Belongs to the 'phage' integrase family
FJR45_RS02980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJR45_RS02985	COG2081	HI0933 family
FJR45_RS02995	COG0556	nucleotide-excision repair
FJR45_RS03005	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FJR45_RS03105	COG0651	ATP synthesis coupled electron transport
FJR45_RS03110	COG0651	ATP synthesis coupled electron transport
FJR45_RS03135	COG1320	monovalent cation:proton antiporter activity
FJR45_RS03145	COG0589	response to stress
FJR45_RS03175	COG2860	membrane
FJR45_RS03180	COG0788	formyltetrahydrofolate deformylase activity
FJR45_RS03185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FJR45_RS03190	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FJR45_RS03200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FJR45_RS03205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FJR45_RS03210	COG0825	malonyl-CoA metabolic process
FJR45_RS03215	COG2176	DNA-directed DNA polymerase activity
FJR45_RS03220	COG0135	phosphoribosylanthranilate isomerase activity
FJR45_RS03225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FJR45_RS03240	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FJR45_RS03245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FJR45_RS03250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FJR45_RS03255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FJR45_RS03260	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FJR45_RS03265	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FJR45_RS03275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FJR45_RS03280	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FJR45_RS03290	COG0495	leucyl-tRNA aminoacylation
FJR45_RS03305	COG0285	dihydrofolate synthase activity
FJR45_RS03310	COG0739	heme binding
FJR45_RS03320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FJR45_RS03325	COG1238	metal cluster binding
FJR45_RS03330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FJR45_RS03340	COG1692	metallophosphoesterase
FJR45_RS03350	COG0745	RESPONSE REGULATOR receiver
FJR45_RS03360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FJR45_RS03370	COG1365	unkown
FJR45_RS03375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FJR45_RS03385	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FJR45_RS03395	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FJR45_RS03400	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FJR45_RS03445	COG0642	Histidine kinase
FJR45_RS03450	COG0745	RESPONSE REGULATOR receiver
FJR45_RS03470	COG0840	transmembrane signaling receptor activity
FJR45_RS03475	COG3707	response regulator
FJR45_RS03480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FJR45_RS03485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FJR45_RS03495	COG0784	Response regulator, receiver
FJR45_RS03495	COG0835	chemotaxis
FJR45_RS03500	COG0643	Histidine kinase
FJR45_RS03500	COG0784	Response regulator, receiver
FJR45_RS03500	COG2198	Histidine kinase
FJR45_RS03505	COG0835	chemotaxis
FJR45_RS03510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FJR45_RS03515	COG1127	ABC transporter
FJR45_RS03520	COG3008	intermembrane lipid transfer
FJR45_RS03520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FJR45_RS03530	COG0006	proline dipeptidase activity
FJR45_RS03540	COG5001	Diguanylate cyclase
FJR45_RS03540	COG4251	negative regulation of phosphorylation
FJR45_RS03540	COG3706	GGDEF domain
FJR45_RS03540	COG2203	Gaf domain
FJR45_RS03545	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FJR45_RS03550	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FJR45_RS03570	COG0488	(ABC) transporter
FJR45_RS03575	COG3706	GGDEF domain
FJR45_RS03600	COG0280	phosphate acetyltransferase
FJR45_RS03600	COG0857	belongs to the CobB CobQ family
FJR45_RS03605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FJR45_RS03610	COG1278	Cold shock
FJR45_RS03635	COG0418	dihydroorotase activity
FJR45_RS03640	COG0745	RESPONSE REGULATOR receiver
FJR45_RS03645	COG0642	Histidine kinase
FJR45_RS03650	COG0811	peptide transport
FJR45_RS03655	COG0848	biopolymer transport protein
FJR45_RS03675	COG0459	protein refolding
FJR45_RS03680	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FJR45_RS03715	COG1283	sodium-dependent phosphate transmembrane transporter activity
FJR45_RS03720	COG0731	radical SAM domain protein
FJR45_RS03725	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FJR45_RS03735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FJR45_RS03740	COG2204	response regulator
FJR45_RS03760	COG0004	ammonium transporteR
FJR45_RS03770	COG0004	ammonium transporteR
FJR45_RS03780	COG1773	rubredoxin
FJR45_RS03810	COG0714	Associated with various cellular activities
FJR45_RS03830	COG2304	oxidoreductase activity
FJR45_RS03840	COG0287	Prephenate dehydrogenase
FJR45_RS03845	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJR45_RS03855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FJR45_RS03860	COG0642	Histidine kinase
FJR45_RS03865	COG0745	RESPONSE REGULATOR receiver
FJR45_RS03875	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FJR45_RS03885	COG0157	Belongs to the NadC ModD family
FJR45_RS03890	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FJR45_RS03905	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FJR45_RS03915	COG0083	homoserine kinase activity
FJR45_RS03920	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FJR45_RS03925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FJR45_RS03930	COG0779	Required for maturation of 30S ribosomal subunits
FJR45_RS03935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJR45_RS03935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJR45_RS03940	COG2226	methyltransferase
FJR45_RS03945	COG1570	exodeoxyribonuclease VII activity
FJR45_RS03955	COG0616	signal peptide processing
FJR45_RS03960	COG0402	S-adenosylhomocysteine deaminase activity
FJR45_RS03965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FJR45_RS03970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FJR45_RS03975	COG1419	protein localization to endoplasmic reticulum
FJR45_RS03980	COG0455	bacterial-type flagellum organization
FJR45_RS03995	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FJR45_RS04000	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FJR45_RS04005	COG0482	sulfurtransferase activity
FJR45_RS04030	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FJR45_RS04045	COG2217	Heavy metal translocating P-type atpase
FJR45_RS04055	COG2863	cytochrome
FJR45_RS04060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FJR45_RS04065	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FJR45_RS04065	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FJR45_RS04085	COG0859	PFAM glycosyl transferase family 9
FJR45_RS04090	COG0463	Glycosyl transferase, family 2
FJR45_RS04105	COG0438	transferase activity, transferring glycosyl groups
FJR45_RS04140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FJR45_RS04145	COG0247	lactate metabolic process
FJR45_RS04150	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FJR45_RS04160	COG2200	EAL domain
FJR45_RS04160	COG3287	FIST C domain
FJR45_RS04160	COG2199	diguanylate cyclase activity
FJR45_RS04165	COG0513	Belongs to the DEAD box helicase family
FJR45_RS04170	COG3287	FIST C domain
FJR45_RS04170	COG2200	EAL domain
FJR45_RS04170	COG2199	diguanylate cyclase activity
FJR45_RS04175	COG0308	aminopeptidase N
FJR45_RS04200	COG0745	RESPONSE REGULATOR receiver
FJR45_RS04205	COG2827	Endonuclease containing a URI domain
FJR45_RS04210	COG2501	S4 domain
FJR45_RS04235	COG0840	transmembrane signaling receptor activity
FJR45_RS04240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FJR45_RS04245	COG0668	transmembrane transport
FJR45_RS04250	COG4895	conserved protein (DUF2196)
FJR45_RS04260	COG2046	Belongs to the sulfate adenylyltransferase family
FJR45_RS04265	COG0745	RESPONSE REGULATOR receiver
FJR45_RS04270	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FJR45_RS04270	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FJR45_RS04275	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FJR45_RS04280	COG0489	protein tyrosine kinase activity
FJR45_RS04300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FJR45_RS04305	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FJR45_RS04315	COG1028	Short-chain dehydrogenase reductase Sdr
FJR45_RS04315	COG3347	Dehydrogenase
FJR45_RS04330	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FJR45_RS04335	COG1216	Glycosyl transferase, family 2
FJR45_RS04335	COG0463	Glycosyl transferase, family 2
FJR45_RS04340	COG1793	dna ligase
FJR45_RS04365	COG1555	photosystem II stabilization
FJR45_RS04385	COG2801	Transposase and inactivated derivatives
FJR45_RS04400	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FJR45_RS04430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FJR45_RS04440	COG2089	acid synthase
FJR45_RS04455	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FJR45_RS04460	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FJR45_RS04485	COG1086	Polysaccharide biosynthesis protein
FJR45_RS04495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FJR45_RS04520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FJR45_RS04525	COG1086	Polysaccharide biosynthesis protein
FJR45_RS04560	COG1287	oligosaccharyl transferase activity
FJR45_RS04580	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FJR45_RS04590	COG0165	Argininosuccinate lyase
FJR45_RS04600	COG0537	adenosine 5'-monophosphoramidase activity
FJR45_RS04605	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FJR45_RS04610	COG0072	phenylalanine-tRNA ligase activity
FJR45_RS04610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJR45_RS04615	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FJR45_RS04620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FJR45_RS04625	COG0539	negative regulation of cytoplasmic translation
FJR45_RS04625	COG1185	polyribonucleotide nucleotidyltransferase activity
FJR45_RS04635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FJR45_RS04640	COG1028	Short-chain dehydrogenase reductase Sdr
FJR45_RS04645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FJR45_RS04665	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FJR45_RS04670	COG0612	Peptidase, M16
FJR45_RS04675	COG0167	dihydroorotate dehydrogenase activity
FJR45_RS04680	COG3300	MHYT domain
FJR45_RS04680	COG5001	Diguanylate cyclase
FJR45_RS04690	COG3335	DDE superfamily endonuclease
FJR45_RS04715	COG1294	oxidase, subunit
FJR45_RS04720	COG1271	oxidase subunit
FJR45_RS04735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FJR45_RS04740	COG0215	cysteine-tRNA ligase activity
FJR45_RS04745	COG0728	peptidoglycan biosynthetic process
FJR45_RS04755	COG0632	four-way junction helicase activity
FJR45_RS04760	COG1181	Belongs to the D-alanine--D-alanine ligase family
FJR45_RS04770	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FJR45_RS04815	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FJR45_RS04820	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FJR45_RS04825	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FJR45_RS04835	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FJR45_RS04850	COG3706	GGDEF domain
FJR45_RS04855	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FJR45_RS04865	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FJR45_RS04870	COG0488	(ABC) transporter
FJR45_RS04890	COG0326	Molecular chaperone. Has ATPase activity
FJR45_RS04930	COG0840	transmembrane signaling receptor activity
FJR45_RS04935	COG0840	transmembrane signaling receptor activity
FJR45_RS04940	COG3287	FIST C domain
FJR45_RS04940	COG2200	EAL domain
FJR45_RS04940	COG2199	diguanylate cyclase activity
FJR45_RS04975	COG0784	Response regulator, receiver
FJR45_RS04975	COG0835	chemotaxis
FJR45_RS04985	COG0243	molybdopterin cofactor binding
FJR45_RS04990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FJR45_RS05015	COG4771	TonB-dependent receptor
FJR45_RS05025	COG1393	Belongs to the ArsC family
FJR45_RS05030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FJR45_RS05045	COG4974	Belongs to the 'phage' integrase family
FJR45_RS05080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FJR45_RS05090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FJR45_RS05090	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FJR45_RS05095	COG0667	Aldo Keto reductase
FJR45_RS05100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FJR45_RS05115	COG0352	thiamine-phosphate diphosphorylase activity
FJR45_RS05130	COG3259	Nickel-dependent hydrogenase
FJR45_RS05135	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FJR45_RS05140	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FJR45_RS05155	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FJR45_RS05175	COG1122	ATPase activity
FJR45_RS05190	COG0310	cobalt ion transport
FJR45_RS05200	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR45_RS05205	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR45_RS05220	COG0375	protein maturation
FJR45_RS05225	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FJR45_RS05225	COG0493	'glutamate synthase
FJR45_RS05235	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FJR45_RS05240	COG0298	carbon dioxide binding
FJR45_RS05245	COG0409	Hydrogenase expression formation protein
FJR45_RS05250	COG0309	Hydrogenase expression formation protein (HypE)
FJR45_RS05255	COG0501	Belongs to the peptidase M48B family
FJR45_RS05270	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FJR45_RS05270	COG1024	Enoyl-CoA hydratase
FJR45_RS05275	COG0375	protein maturation
FJR45_RS05285	COG2081	HI0933 family
FJR45_RS05300	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FJR45_RS05305	COG5001	Diguanylate cyclase
FJR45_RS05310	COG0840	transmembrane signaling receptor activity
FJR45_RS05315	COG2201	protein-glutamate methylesterase activity
FJR45_RS05320	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FJR45_RS05330	COG5002	protein histidine kinase activity
FJR45_RS05340	COG0750	zinc metalloprotease
FJR45_RS05345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FJR45_RS05355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJR45_RS05360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJR45_RS05365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJR45_RS05400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FJR45_RS05450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FJR45_RS05455	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FJR45_RS05465	COG0531	amino acid
FJR45_RS05475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FJR45_RS05490	COG3706	GGDEF domain
FJR45_RS05495	COG1309	transcriptional regulator
FJR45_RS05520	COG0842	Transport permease protein
FJR45_RS05520	COG1129	ABC transporter
FJR45_RS05535	COG3335	DDE superfamily endonuclease
FJR45_RS05545	COG0842	Transport permease protein
FJR45_RS05600	COG1573	uracil-dna glycosylase
FJR45_RS05605	COG2200	EAL domain
FJR45_RS05605	COG3287	FIST C domain
FJR45_RS05605	COG2199	diguanylate cyclase activity
FJR45_RS05645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FJR45_RS05655	COG0822	iron-sulfur transferase activity
FJR45_RS05660	COG1773	rubredoxin
FJR45_RS05675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJR45_RS05680	COG0101	tRNA pseudouridine synthase activity
FJR45_RS05690	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FJR45_RS05695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FJR45_RS05700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FJR45_RS05710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FJR45_RS05715	COG1944	ATP diphosphatase activity
FJR45_RS05725	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FJR45_RS05730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FJR45_RS05745	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FJR45_RS05755	COG1338	Plays a role in the flagellum-specific transport system
FJR45_RS05760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FJR45_RS05770	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FJR45_RS05780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FJR45_RS05785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FJR45_RS05795	COG0521	Mo-molybdopterin cofactor biosynthetic process
FJR45_RS05805	COG0708	Exodeoxyribonuclease III
FJR45_RS05810	COG2703	oxygen carrier activity
FJR45_RS05815	COG2048	Heterodisulfide reductase, subunit B
FJR45_RS05820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FJR45_RS05835	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FJR45_RS05840	COG0585	pseudouridine synthase activity
FJR45_RS05850	COG0243	molybdopterin cofactor binding
FJR45_RS05855	COG0437	4 iron, 4 sulfur cluster binding
FJR45_RS05860	COG0348	domain, Protein
FJR45_RS05865	COG3043	anaerobic respiration
FJR45_RS05880	COG0840	transmembrane signaling receptor activity
FJR45_RS05925	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FJR45_RS05935	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FJR45_RS05940	COG0133	tryptophan synthase activity
FJR45_RS05945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FJR45_RS05955	COG0698	ribose 5-phosphate isomerase
FJR45_RS05960	COG1994	Peptidase M50
FJR45_RS05965	COG0681	Belongs to the peptidase S26 family
FJR45_RS05970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FJR45_RS05990	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FJR45_RS06010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FJR45_RS06015	COG4786	Flagellar basal body rod
FJR45_RS06020	COG4786	Flagellar basal body rod
FJR45_RS06025	COG0066	3-isopropylmalate dehydratase activity
FJR45_RS06030	COG0473	3-isopropylmalate dehydrogenase activity
FJR45_RS06045	COG0788	formyltetrahydrofolate deformylase activity
FJR45_RS06075	COG2171	N-acyltransferase activity
FJR45_RS06095	COG1058	Belongs to the CinA family
FJR45_RS06095	COG1546	Belongs to the CinA family
FJR45_RS06105	COG0563	adenylate kinase activity
FJR45_RS06110	COG0301	tRNA thio-modification
FJR45_RS06110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FJR45_RS06115	COG0563	adenylate kinase activity
FJR45_RS06120	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FJR45_RS06125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FJR45_RS06140	COG1355	regulation of microtubule-based process
FJR45_RS06170	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FJR45_RS06180	COG2703	oxygen carrier activity
FJR45_RS06205	COG0492	ferredoxin-NADP+ reductase activity
FJR45_RS06230	COG2703	oxygen carrier activity
FJR45_RS06245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FJR45_RS06300	COG2801	Transposase and inactivated derivatives
FJR45_RS06315	COG0497	DNA recombination
FJR45_RS06325	COG0084	hydrolase, TatD family'
FJR45_RS06335	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FJR45_RS06340	COG0131	Imidazoleglycerol-phosphate dehydratase
FJR45_RS06345	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FJR45_RS06360	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FJR45_RS06385	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FJR45_RS06395	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FJR45_RS06410	COG0784	Response regulator, receiver
FJR45_RS06410	COG2205	protein histidine kinase activity
FJR45_RS06415	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FJR45_RS06425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FJR45_RS06430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJR45_RS06430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FJR45_RS06440	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FJR45_RS06445	COG1763	Mo-molybdopterin cofactor biosynthetic process
FJR45_RS06460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FJR45_RS06465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FJR45_RS06490	COG1309	transcriptional regulator
FJR45_RS06505	COG0674	pyruvate-flavodoxin oxidoreductase activity
FJR45_RS06505	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FJR45_RS06515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FJR45_RS06520	COG0045	succinate-CoA ligase (ADP-forming) activity
FJR45_RS06525	COG0114	fumarate hydratase activity
FJR45_RS06530	COG0039	L-malate dehydrogenase activity
FJR45_RS06550	COG4591	ABC-type transport system involved in lipoprotein release permease component
FJR45_RS06555	COG0653	protein targeting
FJR45_RS06565	COG1049	propionate catabolic process, 2-methylcitrate cycle
FJR45_RS06575	COG1674	ftsk spoiiie
FJR45_RS06575	COG1196	nuclear chromosome segregation
FJR45_RS06580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FJR45_RS06760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FJR45_RS06785	COG0163	prenyltransferase activity
FJR45_RS06790	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FJR45_RS06795	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FJR45_RS06800	COG0124	histidyl-tRNA synthetase
FJR45_RS06805	COG0069	glutamate synthase activity
FJR45_RS06810	COG1166	arginine decarboxylase activity
FJR45_RS06815	COG1045	serine acetyltransferase
FJR45_RS06830	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FJR45_RS06835	COG0440	acetolactate synthase activity
FJR45_RS06840	COG0028	Belongs to the TPP enzyme family
FJR45_RS06850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FJR45_RS06855	COG1832	CoA-binding protein
FJR45_RS06875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FJR45_RS06910	COG1459	type II secretion system
FJR45_RS06920	COG2165	general secretion pathway protein
FJR45_RS06925	COG3150	esterase
FJR45_RS06945	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FJR45_RS06950	COG1137	ATPase activity
FJR45_RS06955	COG0802	atpase or kinase
FJR45_RS06960	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FJR45_RS06965	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FJR45_RS06980	COG1032	radical SAM domain protein
FJR45_RS07030	COG0745	RESPONSE REGULATOR receiver
FJR45_RS07035	COG2205	protein histidine kinase activity
FJR45_RS07060	COG1227	inorganic diphosphatase activity
FJR45_RS07065	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FJR45_RS07070	COG0730	response to heat
FJR45_RS07080	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FJR45_RS07095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FJR45_RS07110	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FJR45_RS07120	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FJR45_RS07125	COG0493	'glutamate synthase
FJR45_RS07130	COG0069	glutamate synthase activity
FJR45_RS07130	COG0070	glutamate synthase
FJR45_RS07130	COG0067	glutamate synthase
FJR45_RS07150	COG0500	methyltransferase
FJR45_RS07185	COG1730	sister chromatid segregation
FJR45_RS07270	COG3328	transposase activity
FJR45_RS07280	COG0840	transmembrane signaling receptor activity
FJR45_RS07305	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FJR45_RS07320	COG1333	cytochrome c biogenesis protein
FJR45_RS07320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FJR45_RS07325	COG0642	Histidine kinase
FJR45_RS07330	COG1362	aminopeptidase activity
FJR45_RS07345	COG0587	DNA-directed DNA polymerase activity
FJR45_RS07355	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FJR45_RS07365	COG0745	RESPONSE REGULATOR receiver
FJR45_RS07370	COG0343	queuine tRNA-ribosyltransferase activity
FJR45_RS07375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FJR45_RS07380	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FJR45_RS07390	COG0513	Belongs to the DEAD box helicase family
FJR45_RS07420	COG0737	Belongs to the 5'-nucleotidase family
FJR45_RS07425	COG3258	Cytochrome c
FJR45_RS07445	COG0642	Histidine kinase
FJR45_RS07460	COG4232	protein-disulfide reductase activity
FJR45_RS07480	COG1331	Highly conserved protein containing a thioredoxin domain
FJR45_RS07500	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FJR45_RS07505	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FJR45_RS07540	COG0714	Associated with various cellular activities
FJR45_RS07550	COG1592	Rubrerythrin
FJR45_RS07555	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FJR45_RS07570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FJR45_RS07575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FJR45_RS07585	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FJR45_RS07590	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FJR45_RS07595	COG0484	heat shock protein binding
FJR45_RS07605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FJR45_RS07615	COG0849	cell division
FJR45_RS07620	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FJR45_RS07625	COG0484	heat shock protein binding
FJR45_RS07635	COG1136	(ABC) transporter
FJR45_RS07660	COG2890	protein-(glutamine-N5) methyltransferase activity
FJR45_RS07665	COG0501	Belongs to the peptidase M48B family
FJR45_RS07685	COG0471	metal ion transport
FJR45_RS07690	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FJR45_RS07700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FJR45_RS07705	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FJR45_RS07715	COG0356	it plays a direct role in the translocation of protons across the membrane
FJR45_RS07725	COG1418	mRNA catabolic process
FJR45_RS07740	COG0552	protein localization to endoplasmic reticulum
FJR45_RS07760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FJR45_RS07770	COG1580	Controls the rotational direction of flagella during chemotaxis
FJR45_RS07775	COG0736	holo-[acyl-carrier-protein] synthase activity
FJR45_RS07810	COG1193	negative regulation of DNA recombination
FJR45_RS07815	COG2081	HI0933 family
FJR45_RS07820	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FJR45_RS07835	COG3706	GGDEF domain
FJR45_RS07840	COG0525	valine-tRNA ligase activity
FJR45_RS07845	COG0659	secondary active sulfate transmembrane transporter activity
FJR45_RS07860	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FJR45_RS07865	COG1610	YqeY-like protein
FJR45_RS07870	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FJR45_RS07880	COG0284	orotidine-5'-phosphate decarboxylase activity
FJR45_RS07885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FJR45_RS07890	COG2176	DNA-directed DNA polymerase activity
FJR45_RS07900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FJR45_RS07915	COG0745	RESPONSE REGULATOR receiver
FJR45_RS07920	COG0642	Histidine kinase
FJR45_RS07925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FJR45_RS07930	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FJR45_RS07935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FJR45_RS07940	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FJR45_RS07945	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FJR45_RS07950	COG1077	Cell shape determining protein MreB Mrl
FJR45_RS07970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FJR45_RS07990	COG0754	glutathionylspermidine amidase activity
FJR45_RS07995	COG0181	hydroxymethylbilane synthase activity
FJR45_RS08010	COG0442	prolyl-tRNA aminoacylation
FJR45_RS08015	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FJR45_RS08035	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FJR45_RS08045	COG0531	amino acid
FJR45_RS08050	COG1663	tetraacyldisaccharide 4'-kinase activity
FJR45_RS08055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FJR45_RS08060	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FJR45_RS08065	COG3437	response regulator, receiver
FJR45_RS08065	COG0784	Response regulator, receiver
FJR45_RS08095	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FJR45_RS08095	COG2050	protein possibly involved in aromatic compounds catabolism
FJR45_RS08100	COG0500	methyltransferase
FJR45_RS08115	COG0585	pseudouridine synthase activity
FJR45_RS08120	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FJR45_RS08120	COG1796	DNA polymerase
FJR45_RS08130	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FJR45_RS08130	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FJR45_RS08135	COG0196	riboflavin kinase activity
FJR45_RS08145	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FJR45_RS08155	COG0408	coproporphyrinogen oxidase activity
FJR45_RS08185	COG0137	argininosuccinate synthase activity
FJR45_RS08195	COG0359	binds to the 23S rRNA
FJR45_RS08200	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FJR45_RS08205	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FJR45_RS08240	COG4796	Type ii and iii secretion system protein
FJR45_RS08260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FJR45_RS08285	COG1739	Uncharacterized protein family UPF0029
FJR45_RS08290	COG0217	transcriptional regulatory protein
FJR45_RS08305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FJR45_RS08310	COG1722	exodeoxyribonuclease VII activity
FJR45_RS08320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FJR45_RS08325	COG3093	addiction module antidote protein HigA
FJR45_RS08330	COG3549	Plasmid maintenance system killer
FJR45_RS08355	COG0275	rRNA processing
FJR45_RS08360	COG0745	RESPONSE REGULATOR receiver
FJR45_RS08375	COG3256	nitric oxide reductase
FJR45_RS08390	COG0535	radical SAM domain protein
FJR45_RS08400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FJR45_RS08400	COG1648	precorrin-2 dehydrogenase activity
FJR45_RS08420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FJR45_RS08445	COG1648	precorrin-2 dehydrogenase activity
FJR45_RS08445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FJR45_RS08450	COG1522	sequence-specific DNA binding
FJR45_RS08470	COG2151	metal-sulfur cluster biosynthetic enzyme
FJR45_RS08490	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FJR45_RS08495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FJR45_RS08505	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FJR45_RS08520	COG2884	Cell division ATP-binding protein ftsE
FJR45_RS08525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FJR45_RS08535	COG0564	pseudouridine synthase activity
FJR45_RS08540	COG0772	Belongs to the SEDS family
FJR45_RS08545	COG1132	(ABC) transporter
FJR45_RS08585	COG1546	Belongs to the CinA family
FJR45_RS08585	COG1058	Belongs to the CinA family
FJR45_RS08590	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FJR45_RS08600	COG0154	amidase activity
FJR45_RS08615	COG0516	GMP reductase activity
FJR45_RS08615	COG0517	IMP dehydrogenase activity
FJR45_RS08640	COG0745	RESPONSE REGULATOR receiver
FJR45_RS08645	COG0642	Histidine kinase
FJR45_RS08650	COG1714	RDD family
FJR45_RS08655	COG0037	tRNA processing
FJR45_RS08660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FJR45_RS08665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FJR45_RS08665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FJR45_RS08670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FJR45_RS08675	COG2204	response regulator
FJR45_RS08680	COG1047	Peptidyl-prolyl cis-trans
FJR45_RS08695	COG0823	Involved in the tonB-independent uptake of proteins
FJR45_RS08705	COG0848	biopolymer transport protein
FJR45_RS08710	COG0811	peptide transport
FJR45_RS08715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FJR45_RS08720	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FJR45_RS08725	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FJR45_RS08730	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FJR45_RS08735	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FJR45_RS08750	COG1475	DNA binding
FJR45_RS08755	COG1192	Involved in chromosome partitioning
FJR45_RS08765	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FJR45_RS08770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FJR45_RS08775	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FJR45_RS08780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FJR45_RS08785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FJR45_RS08795	COG0251	oxidation-reduction process
FJR45_RS08805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FJR45_RS08815	COG0134	indole-3-glycerol-phosphate synthase activity
FJR45_RS08825	COG0727	PFAM Uncharacterised protein family (UPF0153)
FJR45_RS08830	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FJR45_RS08835	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FJR45_RS08840	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FJR45_RS08855	COG2404	hydrolase activity, acting on ester bonds
FJR45_RS08860	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FJR45_RS08875	COG0860	N-Acetylmuramoyl-L-alanine amidase
FJR45_RS08885	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FJR45_RS08895	COG1758	RNA polymerase activity
FJR45_RS08900	COG0528	UMP kinase activity
FJR45_RS08915	COG0243	molybdopterin cofactor binding
FJR45_RS08945	COG2223	nitrite transmembrane transporter activity
FJR45_RS08950	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FJR45_RS08955	COG2116	formate transmembrane transporter activity
FJR45_RS08960	COG0631	protein serine/threonine phosphatase activity
FJR45_RS08970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FJR45_RS08975	COG0339	signal peptide processing
FJR45_RS09015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FJR45_RS09030	COG0512	Glutamine amidotransferase of anthranilate synthase
FJR45_RS09035	COG0628	permease
FJR45_RS09040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FJR45_RS09045	COG4786	Flagellar basal body rod
FJR45_RS09045	COG1256	bacterial-type flagellum assembly
FJR45_RS09060	COG3951	Flagellar rod assembly protein muramidase FlgJ
FJR45_RS09065	COG1706	bacterial-type flagellum-dependent cell motility
FJR45_RS09070	COG0742	ribosomal rna small subunit methyltransferase
FJR45_RS09095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FJR45_RS09105	COG0484	heat shock protein binding
FJR45_RS09110	COG0138	bifunctional purine biosynthesis protein purh
FJR45_RS09115	COG0205	6-phosphofructokinase activity
FJR45_RS09125	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FJR45_RS09150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FJR45_RS09165	COG0557	exoribonuclease II activity
FJR45_RS09180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FJR45_RS09185	COG0481	GTPase activity
FJR45_RS09200	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FJR45_RS09205	COG0443	Heat shock 70 kDa protein
FJR45_RS09220	COG0745	RESPONSE REGULATOR receiver
FJR45_RS09240	COG0848	biopolymer transport protein
FJR45_RS09250	COG0811	peptide transport
FJR45_RS09320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FJR45_RS09335	COG0793	Belongs to the peptidase S41A family
FJR45_RS09340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FJR45_RS09345	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FJR45_RS09350	COG0047	phosphoribosylformylglycinamidine synthase activity
FJR45_RS09360	COG0204	Acyl-transferase
FJR45_RS09365	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FJR45_RS09370	COG1132	(ABC) transporter
FJR45_RS09385	COG3787	Belongs to the UPF0306 family
FJR45_RS09395	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FJR45_RS09400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FJR45_RS09405	COG1496	oxidoreductase activity
FJR45_RS09410	COG1959	2 iron, 2 sulfur cluster binding
FJR45_RS09420	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FJR45_RS09430	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FJR45_RS09440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FJR45_RS09445	COG1605	Chorismate mutase
FJR45_RS09445	COG0077	Prephenate dehydratase
FJR45_RS09455	COG0019	diaminopimelate decarboxylase activity
FJR45_RS09465	COG0193	aminoacyl-tRNA hydrolase activity
FJR45_RS09470	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FJR45_RS09495	COG4191	Histidine kinase
FJR45_RS09500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FJR45_RS09505	COG0540	Belongs to the ATCase OTCase family
FJR45_RS09510	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FJR45_RS09525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FJR45_RS09540	COG2200	EAL domain
FJR45_RS09540	COG3287	FIST C domain
FJR45_RS09540	COG2199	diguanylate cyclase activity
FJR45_RS09545	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FJR45_RS09550	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FJR45_RS09560	COG0706	membrane insertase activity
FJR45_RS09565	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FJR45_RS09570	COG0594	ribonuclease P activity
FJR45_RS09575	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FJR45_RS09580	COG0542	response to heat
FJR45_RS09590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FJR45_RS09600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FJR45_RS09610	COG2226	methyltransferase
FJR45_RS09670	COG0776	regulation of translation
FJR45_RS09775	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FJR45_RS09785	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FJR45_RS09800	COG0527	aspartate kinase activity
FJR45_RS09805	COG0494	nUDIX hydrolase
FJR45_RS09810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FJR45_RS09815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FJR45_RS09820	COG0805	protein transport
FJR45_RS09825	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FJR45_RS09830	COG0439	Biotin carboxylase
FJR45_RS09845	COG2861	carbohydrate metabolic process
FJR45_RS09865	COG0360	Binds together with S18 to 16S ribosomal RNA
FJR45_RS09870	COG0629	single-stranded DNA binding
FJR45_RS09875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FJR45_RS09895	COG0560	Phosphoserine phosphatase
FJR45_RS09905	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FJR45_RS09920	COG1278	Cold shock
FJR45_RS09930	COG1181	Belongs to the D-alanine--D-alanine ligase family
FJR45_RS09950	COG0688	phosphatidylethanolamine metabolic process
FJR45_RS09955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FJR45_RS09960	COG2264	protein methyltransferase activity
FJR45_RS09965	COG0745	RESPONSE REGULATOR receiver
FJR45_RS09970	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FJR45_RS09975	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FJR45_RS09995	COG0628	permease
FJR45_RS10000	COG2255	four-way junction helicase activity
FJR45_RS10005	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FJR45_RS10015	COG0159	tryptophan synthase activity
FJR45_RS10075	COG2873	o-acetylhomoserine
FJR45_RS10080	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FJR45_RS10085	COG0542	response to heat
FJR45_RS10090	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FJR45_RS10125	COG0189	ligase activity
FJR45_RS10135	COG0335	large ribosomal subunit rRNA binding
FJR45_RS10140	COG0336	Belongs to the RNA methyltransferase TrmD family
FJR45_RS10145	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FJR45_RS10155	COG0228	four-way junction DNA binding
FJR45_RS10160	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FJR45_RS10165	COG0564	pseudouridine synthase activity
FJR45_RS10170	COG1519	Transferase
FJR45_RS10180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FJR45_RS10195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FJR45_RS10200	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FJR45_RS10205	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FJR45_RS10210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FJR45_RS10240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FJR45_RS10250	COG1671	Belongs to the UPF0178 family
FJR45_RS10255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FJR45_RS10260	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FJR45_RS10310	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FJR45_RS10315	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FJR45_RS10330	COG0752	glycyl-tRNA synthetase alpha subunit
FJR45_RS10350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FJR45_RS10355	COG0826	peptidase U32
FJR45_RS10365	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FJR45_RS10375	COG3118	belongs to the thioredoxin family
FJR45_RS10385	COG0492	ferredoxin-NADP+ reductase activity
FJR45_RS10405	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FJR45_RS10415	COG1007	ATP synthesis coupled electron transport
FJR45_RS10425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FJR45_RS10430	COG0713	ATP synthesis coupled electron transport
FJR45_RS10435	COG0839	Belongs to the complex I subunit 6 family
FJR45_RS10440	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR45_RS10445	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FJR45_RS10450	COG1034	ATP synthesis coupled electron transport
FJR45_RS10470	COG0649	NAD binding
FJR45_RS10475	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR45_RS10480	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR45_RS10485	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FJR45_RS10490	COG1222	aaa ATPase
FJR45_RS10500	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FJR45_RS10540	COG4962	Type ii secretion system protein e
FJR45_RS10565	COG4796	Type ii and iii secretion system protein
FJR45_RS10585	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FJR45_RS10590	COG1242	4 iron, 4 sulfur cluster binding
FJR45_RS10605	COG0140	phosphoribosyl-ATP diphosphatase activity
FJR45_RS10605	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FJR45_RS10635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FJR45_RS10645	COG0581	inorganic phosphate transmembrane transporter activity
FJR45_RS10650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FJR45_RS10670	COG3706	GGDEF domain
FJR45_RS10680	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FJR45_RS10685	COG0174	glutamine synthetase
FJR45_RS10700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FJR45_RS10705	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FJR45_RS10710	COG0444	Belongs to the ABC transporter superfamily
FJR45_RS10715	COG0156	8-amino-7-oxononanoate synthase activity
FJR45_RS10730	COG0424	maF-like protein
FJR45_RS10740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FJR45_RS10755	COG4716	Myosin-crossreactive antigen
FJR45_RS10760	COG1234	tRNA 3'-trailer cleavage
FJR45_RS10790	COG1012	belongs to the aldehyde dehydrogenase family
FJR45_RS10800	COG3437	response regulator, receiver
FJR45_RS10800	COG0784	Response regulator, receiver
FJR45_RS10805	COG0792	nuclease activity
FJR45_RS10810	COG3383	formate dehydrogenase (NAD+) activity
FJR45_RS10820	COG0460	homoserine dehydrogenase
FJR45_RS10825	COG0436	Aminotransferase
FJR45_RS10850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FJR45_RS10855	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FJR45_RS10860	COG0254	rRNA binding
FJR45_RS10875	COG0303	'Molybdopterin
FJR45_RS10880	COG2151	metal-sulfur cluster biosynthetic enzyme
FJR45_RS10885	COG2166	iron-sulfur cluster assembly
FJR45_RS10890	COG0719	Fe-S assembly protein
FJR45_RS10895	COG0396	ATPase activity
FJR45_RS10900	COG0719	Fe-S assembly protein
FJR45_RS10910	COG0602	queuosine metabolic process
FJR45_RS10915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FJR45_RS10930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FJR45_RS10935	COG0723	plastoquinol--plastocyanin reductase activity
FJR45_RS10945	COG0445	tRNA wobble uridine modification
FJR45_RS10965	COG0514	ATP-dependent DNA helicase (RecQ)
FJR45_RS10970	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FJR45_RS10975	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FJR45_RS10995	COG4942	peptidase
FJR45_RS11010	COG1854	S-ribosylhomocysteine lyase activity
FJR45_RS11015	COG1013	pyruvate-flavodoxin oxidoreductase activity
FJR45_RS11020	COG0674	pyruvate-flavodoxin oxidoreductase activity
FJR45_RS11025	COG1144	Oxidoreductase
FJR45_RS11030	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FJR45_RS11040	COG4166	transmembrane transport
FJR45_RS11050	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FJR45_RS11055	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FJR45_RS11080	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FJR45_RS11090	COG5002	protein histidine kinase activity
FJR45_RS11090	COG5001	Diguanylate cyclase
FJR45_RS11095	COG5002	protein histidine kinase activity
FJR45_RS11095	COG5001	Diguanylate cyclase
FJR45_RS11105	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FJR45_RS11110	COG1185	polyribonucleotide nucleotidyltransferase activity
FJR45_RS11120	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FJR45_RS11145	COG0519	Catalyzes the synthesis of GMP from XMP
FJR45_RS11145	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FJR45_RS11155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FJR45_RS11165	COG0322	excinuclease ABC activity
FJR45_RS11170	COG0840	transmembrane signaling receptor activity
FJR45_RS11185	COG0784	Response regulator, receiver
FJR45_RS11190	COG1074	ATP-dependent DNA helicase activity
FJR45_RS11205	COG1401	restriction endodeoxyribonuclease activity
FJR45_RS11250	COG3278	Belongs to the heme-copper respiratory oxidase family
FJR45_RS11280	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FJR45_RS11285	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FJR45_RS11290	COG1968	undecaprenyl-diphosphatase activity
FJR45_RS11295	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FJR45_RS11300	COG2814	Major facilitator Superfamily
FJR45_RS11315	COG0840	transmembrane signaling receptor activity
FJR45_RS11330	COG1131	(ABC) transporter
FJR45_RS11345	COG2863	cytochrome
FJR45_RS11350	COG0437	4 iron, 4 sulfur cluster binding
FJR45_RS11365	COG4263	nitrous-oxide reductase activity
FJR45_RS11395	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FJR45_RS11405	COG0129	dihydroxy-acid dehydratase activity
FJR45_RS11445	COG1643	Atp-dependent helicase
FJR45_RS11450	COG1858	cytochrome C peroxidase
FJR45_RS11465	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FJR45_RS11470	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FJR45_RS11530	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FJR45_RS11540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FJR45_RS11565	COG1393	Belongs to the ArsC family
FJR45_RS11570	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FJR45_RS11580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FJR45_RS11585	COG1858	cytochrome C peroxidase
FJR45_RS11595	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FJR45_RS11600	COG1858	cytochrome C peroxidase
FJR45_RS11610	COG1132	(ABC) transporter
FJR45_RS11615	COG1194	a g-specific adenine glycosylase
FJR45_RS11625	COG0745	RESPONSE REGULATOR receiver
FJR45_RS11630	COG0642	Histidine kinase
FJR45_RS11650	COG2199	diguanylate cyclase activity
FJR45_RS11680	COG2270	Major facilitator Superfamily
FJR45_RS11690	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FJR45_RS11695	COG2193	ferroxidase activity
FJR45_RS11700	COG0642	Histidine kinase
FJR45_RS11705	COG0745	RESPONSE REGULATOR receiver
FJR45_RS11735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FJR45_RS11755	COG4232	protein-disulfide reductase activity
FJR45_RS11760	COG2132	Multicopper oxidase
FJR45_RS11785	COG2217	Heavy metal translocating P-type atpase
FJR45_RS11815	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FJR45_RS11820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FJR45_RS11820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FJR45_RS11840	COG0069	glutamate synthase activity
FJR45_RS11870	COG0488	(ABC) transporter
FJR45_RS11875	COG0513	Belongs to the DEAD box helicase family
FJR45_RS11880	COG0745	RESPONSE REGULATOR receiver
FJR45_RS11885	COG3287	FIST C domain
FJR45_RS11885	COG2199	diguanylate cyclase activity
FJR45_RS11885	COG2200	EAL domain
FJR45_RS11925	COG1104	cysteine desulfurase activity
FJR45_RS11935	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FJR45_RS11940	COG0746	molybdenum cofactor guanylyltransferase activity
FJR45_RS11945	COG0315	cyclic pyranopterin monophosphate synthase activity
FJR45_RS11975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FJR45_RS12010	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FJR45_RS12015	COG0571	ribonuclease III activity
FJR45_RS12020	COG0328	RNA-DNA hybrid ribonuclease activity
FJR45_RS12035	COG2855	membrane
FJR45_RS12040	COG0348	domain, Protein
FJR45_RS12070	COG0646	methionine synthase
FJR45_RS12070	COG1410	methionine synthase
FJR45_RS12085	COG0606	chelatase, subunit chli
FJR45_RS12090	COG0242	peptide deformylase activity
FJR45_RS12100	COG0740	serine-type endopeptidase activity
FJR45_RS12105	COG0544	peptidyl-prolyl cis-trans isomerase activity
FJR45_RS12110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FJR45_RS12115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FJR45_RS12120	COG0268	Binds directly to 16S ribosomal RNA
FJR45_RS12125	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FJR45_RS12130	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FJR45_RS12135	COG0237	dephospho-CoA kinase activity
FJR45_RS12140	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FJR45_RS12155	COG2067	long-chain fatty acid transport protein
FJR45_RS12180	COG0670	Belongs to the BI1 family
FJR45_RS12185	COG0352	thiamine-phosphate diphosphorylase activity
FJR45_RS12195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FJR45_RS12200	COG1121	(ABC) transporter
FJR45_RS12205	COG3443	Belongs to the bacterial solute-binding protein 9 family
FJR45_RS12205	COG0803	Belongs to the bacterial solute-binding protein 9 family
FJR45_RS12210	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FJR45_RS12215	COG0233	cytoplasmic translational termination
FJR45_RS12220	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FJR45_RS12230	COG0504	CTP synthase activity
FJR45_RS12235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FJR45_RS12245	COG1157	protein secretion by the type III secretion system
FJR45_RS12250	COG0302	gtp cyclohydrolase
FJR45_RS12255	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FJR45_RS12260	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FJR45_RS12270	COG0107	imidazoleglycerol-phosphate synthase activity
FJR45_RS12280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FJR45_RS12285	COG0564	pseudouridine synthase activity
FJR45_RS12290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FJR45_RS12295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FJR45_RS12305	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FJR45_RS12315	COG3123	guanosine phosphorylase activity
FJR45_RS12320	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group