locus-tag	class	description
EL388_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EL388_RS00060	COG2801	Transposase and inactivated derivatives
EL388_RS00070	COG2842	Transposition protein
EL388_RS00245	COG1671	Belongs to the UPF0178 family
EL388_RS00250	COG1028	Short-chain dehydrogenase reductase Sdr
EL388_RS00255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EL388_RS00260	COG2210	Belongs to the sulfur carrier protein TusA family
EL388_RS00265	COG0583	DNA-binding transcription factor activity
EL388_RS00270	COG0450	alkyl hydroperoxide reductase
EL388_RS00285	COG2922	Belongs to the Smg family
EL388_RS00290	COG0758	DNA mediated transformation
EL388_RS00300	COG0242	peptide deformylase activity
EL388_RS00305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EL388_RS00325	COG5000	phosphorelay sensor kinase activity
EL388_RS00330	COG2204	response regulator
EL388_RS00335	COG0569	domain protein
EL388_RS00340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EL388_RS00350	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EL388_RS00355	COG2226	methyltransferase
EL388_RS00365	COG2853	Lipoprotein
EL388_RS00405	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EL388_RS00410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL388_RS00515	COG4383	Mu-like prophage protein gp29
EL388_RS00535	COG5005	Phage virion morphogenesis
EL388_RS00545	COG4397	Mu-like prophage major head subunit gpT
EL388_RS00635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL388_RS00650	COG2197	response regulator
EL388_RS00655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EL388_RS00665	COG0018	arginyl-trna synthetase
EL388_RS00670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EL388_RS00695	COG1074	ATP-dependent DNA helicase activity
EL388_RS00700	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EL388_RS00715	COG0494	nUDIX hydrolase
EL388_RS00730	COG2847	Copper chaperone PCu(A)C
EL388_RS00740	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EL388_RS00745	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EL388_RS00760	COG3746	phosphate-selective porin O and P
EL388_RS00770	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EL388_RS00785	COG0523	cobalamin synthesis protein
EL388_RS00790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EL388_RS00795	COG2329	Antibiotic biosynthesis monooxygenase
EL388_RS00800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EL388_RS00805	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EL388_RS00810	COG1127	ABC transporter
EL388_RS00825	COG3150	esterase
EL388_RS00830	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EL388_RS00840	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EL388_RS00850	COG2944	sequence-specific DNA binding
EL388_RS00875	COG4797	methyltransferase
EL388_RS00875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EL388_RS00880	COG1278	Cold shock
EL388_RS00885	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EL388_RS00900	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EL388_RS00905	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EL388_RS00915	COG0408	coproporphyrinogen oxidase activity
EL388_RS00935	COG0348	domain, Protein
EL388_RS00945	COG0811	peptide transport
EL388_RS00950	COG0848	biopolymer transport protein
EL388_RS00960	COG0009	L-threonylcarbamoyladenylate synthase
EL388_RS00965	COG0151	Belongs to the GarS family
EL388_RS00970	COG0138	bifunctional purine biosynthesis protein purh
EL388_RS00975	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EL388_RS00985	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EL388_RS01000	COG0799	negative regulation of ribosome biogenesis
EL388_RS01005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EL388_RS01010	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EL388_RS01015	COG1466	dna polymerase III delta subunit
EL388_RS01025	COG0495	leucyl-tRNA aminoacylation
EL388_RS01030	COG3954	Phosphoribulokinase
EL388_RS01035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EL388_RS01040	COG2146	nitrite reductase [NAD(P)H] activity
EL388_RS01045	COG0243	molybdopterin cofactor binding
EL388_RS01055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EL388_RS01060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EL388_RS01065	COG1116	anion transmembrane transporter activity
EL388_RS01070	COG0840	transmembrane signaling receptor activity
EL388_RS01080	COG0210	DNA helicase
EL388_RS01085	COG4191	Histidine kinase
EL388_RS01120	COG0746	molybdenum cofactor guanylyltransferase activity
EL388_RS01130	COG0254	rRNA binding
EL388_RS01135	COG3001	Fructosamine kinase
EL388_RS01160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EL388_RS01180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EL388_RS01195	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EL388_RS01195	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EL388_RS01215	COG4133	protoheme IX ABC transporter activity
EL388_RS01225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EL388_RS01230	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EL388_RS01235	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EL388_RS01275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL388_RS01280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EL388_RS01295	COG0037	tRNA processing
EL388_RS01300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL388_RS01305	COG4232	protein-disulfide reductase activity
EL388_RS01310	COG1324	tolerance protein
EL388_RS01320	COG0628	permease
EL388_RS01325	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EL388_RS01330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EL388_RS01340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EL388_RS01345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EL388_RS01360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EL388_RS01395	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EL388_RS01400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EL388_RS01435	COG0494	nUDIX hydrolase
EL388_RS01440	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EL388_RS01445	COG1970	mechanosensitive ion channel activity
EL388_RS01455	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EL388_RS01460	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EL388_RS01470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL388_RS01475	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EL388_RS01480	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EL388_RS01485	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EL388_RS01505	COG1965	Belongs to the frataxin family
EL388_RS01510	COG0165	Argininosuccinate lyase
EL388_RS01520	COG0181	hydroxymethylbilane synthase activity
EL388_RS01530	COG2959	enzyme of heme biosynthesis
EL388_RS01540	COG2081	HI0933 family
EL388_RS01545	COG0543	2 iron, 2 sulfur cluster binding
EL388_RS01545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EL388_RS01560	COG1678	Uncharacterized ACR, COG1678
EL388_RS01565	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EL388_RS01575	COG0540	Belongs to the ATCase OTCase family
EL388_RS01585	COG1067	ATP-dependent peptidase activity
EL388_RS01625	COG1131	(ABC) transporter
EL388_RS01645	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EL388_RS01650	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EL388_RS01655	COG1040	competence protein
EL388_RS01665	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EL388_RS01670	COG0156	8-amino-7-oxononanoate synthase activity
EL388_RS01680	COG2226	methyltransferase
EL388_RS01700	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EL388_RS01730	COG0109	protoheme IX farnesyltransferase activity
EL388_RS01735	COG1959	2 iron, 2 sulfur cluster binding
EL388_RS01740	COG1999	signal sequence binding
EL388_RS01745	COG3278	Belongs to the heme-copper respiratory oxidase family
EL388_RS01760	COG2010	Cytochrome c
EL388_RS01765	COG0348	domain, Protein
EL388_RS01780	COG3300	MHYT domain
EL388_RS01780	COG5001	Diguanylate cyclase
EL388_RS01785	COG0586	Pfam SNARE associated Golgi protein
EL388_RS01790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EL388_RS01795	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EL388_RS01800	COG1862	Preprotein translocase
EL388_RS01805	COG0343	queuine tRNA-ribosyltransferase activity
EL388_RS01810	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EL388_RS01820	COG0778	Nitroreductase
EL388_RS01825	COG0736	holo-[acyl-carrier-protein] synthase activity
EL388_RS01830	COG1472	Belongs to the glycosyl hydrolase 3 family
EL388_RS01835	COG1230	cation diffusion facilitator family transporter
EL388_RS01845	COG1573	uracil-dna glycosylase
EL388_RS01860	COG0322	excinuclease ABC activity
EL388_RS01885	COG0779	Required for maturation of 30S ribosomal subunits
EL388_RS01890	COG0195	Participates in both transcription termination and antitermination
EL388_RS01890	COG2251	uridine kinase activity
EL388_RS01895	COG3064	Membrane
EL388_RS01895	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EL388_RS01900	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EL388_RS01905	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EL388_RS01910	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EL388_RS01915	COG1185	polyribonucleotide nucleotidyltransferase activity
EL388_RS01925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EL388_RS01930	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EL388_RS01950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EL388_RS01955	COG1881	PFAM PEBP family protein
EL388_RS01965	COG0741	lytic transglycosylase activity
EL388_RS01970	COG0442	prolyl-tRNA aminoacylation
EL388_RS01975	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EL388_RS01980	COG0494	nUDIX hydrolase
EL388_RS01995	COG0489	protein tyrosine kinase activity
EL388_RS02000	COG0717	Belongs to the dCTP deaminase family
EL388_RS02010	COG0360	Binds together with S18 to 16S ribosomal RNA
EL388_RS02015	COG2965	DNA replication, synthesis of RNA primer
EL388_RS02020	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EL388_RS02025	COG0359	binds to the 23S rRNA
EL388_RS02030	COG0305	Participates in initiation and elongation during chromosome replication
EL388_RS02040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EL388_RS02045	COG0134	indole-3-glycerol-phosphate synthase activity
EL388_RS02075	COG1596	polysaccharide export
EL388_RS02075	COG1555	photosystem II stabilization
EL388_RS02080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EL388_RS02085	COG2177	Part of the ABC transporter FtsEX involved in
EL388_RS02090	COG2884	Cell division ATP-binding protein ftsE
EL388_RS02100	COG0612	Peptidase, M16
EL388_RS02105	COG0612	Peptidase, M16
EL388_RS02110	COG0742	ribosomal rna small subunit methyltransferase
EL388_RS02115	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EL388_RS02120	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EL388_RS02125	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EL388_RS02135	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EL388_RS02140	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EL388_RS02150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EL388_RS02155	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EL388_RS02160	COG0193	aminoacyl-tRNA hydrolase activity
EL388_RS02165	COG0012	GTP binding
EL388_RS02215	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EL388_RS02225	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EL388_RS02235	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EL388_RS02240	COG0081	regulation of translation
EL388_RS02245	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EL388_RS02260	COG0085	RNA polymerase activity
EL388_RS02265	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EL388_RS02270	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EL388_RS02275	COG0049	tRNA binding
EL388_RS02280	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EL388_RS02285	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EL388_RS02290	COG0051	transcription antitermination factor activity, RNA binding
EL388_RS02295	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EL388_RS02300	COG0088	Forms part of the polypeptide exit tunnel
EL388_RS02305	COG0089	rRNA binding
EL388_RS02310	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EL388_RS02315	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EL388_RS02320	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EL388_RS02325	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EL388_RS02335	COG0255	Belongs to the universal ribosomal protein uL29 family
EL388_RS02340	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EL388_RS02345	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EL388_RS02350	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EL388_RS02355	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EL388_RS02360	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EL388_RS02365	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EL388_RS02375	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EL388_RS02380	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EL388_RS02385	COG1841	ribosomal large subunit assembly
EL388_RS02395	COG0201	protein transport
EL388_RS02400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EL388_RS02405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EL388_RS02410	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EL388_RS02415	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EL388_RS02420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EL388_RS02425	COG0202	RNA polymerase activity
EL388_RS02430	COG0203	ribosomal protein L17
EL388_RS02440	COG1187	pseudouridine synthase activity
EL388_RS02465	COG2814	Major facilitator Superfamily
EL388_RS02470	COG0629	single-stranded DNA binding
EL388_RS02475	COG2197	response regulator
EL388_RS02480	COG2205	protein histidine kinase activity
EL388_RS02480	COG0784	Response regulator, receiver
EL388_RS02480	COG2198	Histidine kinase
EL388_RS02485	COG2067	long-chain fatty acid transport protein
EL388_RS02490	COG0204	Acyl-transferase
EL388_RS02490	COG0318	PFAM AMP-dependent synthetase and ligase
EL388_RS02510	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EL388_RS02530	COG3568	Endonuclease Exonuclease Phosphatase
EL388_RS02535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EL388_RS02545	COG0433	COG0433 Predicted ATPase
EL388_RS02550	COG0583	DNA-binding transcription factor activity
EL388_RS02555	COG3038	cytochrome b561
EL388_RS02570	COG1741	Belongs to the pirin family
EL388_RS02575	COG0431	NADPH-dependent FMN reductase
EL388_RS02580	COG0217	transcriptional regulatory protein
EL388_RS02590	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EL388_RS02595	COG0632	four-way junction helicase activity
EL388_RS02600	COG2255	four-way junction helicase activity
EL388_RS02605	COG0824	Thioesterase
EL388_RS02630	COG0823	Involved in the tonB-independent uptake of proteins
EL388_RS02635	COG2885	chlorophyll binding
EL388_RS02645	COG0602	queuosine metabolic process
EL388_RS02650	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EL388_RS02670	COG0028	Belongs to the TPP enzyme family
EL388_RS02680	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EL388_RS02685	COG0688	phosphatidylethanolamine metabolic process
EL388_RS02690	COG1183	phosphatidylcholine synthase activity
EL388_RS02695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EL388_RS02720	COG0045	succinate-CoA ligase (ADP-forming) activity
EL388_RS02725	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EL388_RS02730	COG1127	ABC transporter
EL388_RS02745	COG0525	valine-tRNA ligase activity
EL388_RS02755	COG0314	molybdopterin synthase activity
EL388_RS02760	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EL388_RS02765	COG0303	'Molybdopterin
EL388_RS02770	COG1763	Mo-molybdopterin cofactor biosynthetic process
EL388_RS02775	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EL388_RS02790	COG0837	glucose binding
EL388_RS02795	COG5001	Diguanylate cyclase
EL388_RS02795	COG3447	MASE1 domain protein
EL388_RS02795	COG5002	protein histidine kinase activity
EL388_RS02805	COG0519	Catalyzes the synthesis of GMP from XMP
EL388_RS02805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EL388_RS02810	COG1469	GTP cyclohydrolase I activity
EL388_RS02815	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EL388_RS02820	COG0142	geranyltranstransferase activity
EL388_RS02825	COG1722	exodeoxyribonuclease VII activity
EL388_RS02840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EL388_RS02855	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EL388_RS02860	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EL388_RS02875	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EL388_RS02880	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EL388_RS02895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EL388_RS02920	COG0840	transmembrane signaling receptor activity
EL388_RS02925	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EL388_RS02935	COG0335	large ribosomal subunit rRNA binding
EL388_RS02940	COG0336	Belongs to the RNA methyltransferase TrmD family
EL388_RS02945	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EL388_RS02950	COG0228	four-way junction DNA binding
EL388_RS02955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EL388_RS02960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EL388_RS02965	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EL388_RS02970	COG1047	Peptidyl-prolyl cis-trans
EL388_RS02975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EL388_RS02980	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EL388_RS02985	COG0196	riboflavin kinase activity
EL388_RS02995	COG0268	Binds directly to 16S ribosomal RNA
EL388_RS03005	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EL388_RS03015	COG1233	COG1233 Phytoene dehydrogenase and related
EL388_RS03030	COG2048	Heterodisulfide reductase, subunit B
EL388_RS03070	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EL388_RS03075	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EL388_RS03080	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EL388_RS03095	COG0617	tRNA 3'-terminal CCA addition
EL388_RS03100	COG0811	peptide transport
EL388_RS03105	COG0848	biopolymer transport protein
EL388_RS03110	COG1663	tetraacyldisaccharide 4'-kinase activity
EL388_RS03115	COG1663	tetraacyldisaccharide 4'-kinase activity
EL388_RS03115	COG2835	tetraacyldisaccharide 4'-kinase activity
EL388_RS03135	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EL388_RS03165	COG0500	methyltransferase
EL388_RS03170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EL388_RS03175	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EL388_RS03180	COG1234	tRNA 3'-trailer cleavage
EL388_RS03185	COG0513	Belongs to the DEAD box helicase family
EL388_RS03200	COG0247	lactate metabolic process
EL388_RS03210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EL388_RS03220	COG4206	TonB-dependent receptor
EL388_RS03265	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EL388_RS03270	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EL388_RS03275	COG0563	adenylate kinase activity
EL388_RS03285	COG0205	6-phosphofructokinase activity
EL388_RS03295	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EL388_RS03330	COG2046	Belongs to the sulfate adenylyltransferase family
EL388_RS03350	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EL388_RS03355	COG2198	Histidine kinase
EL388_RS03355	COG0784	Response regulator, receiver
EL388_RS03355	COG0643	Histidine kinase
EL388_RS03360	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EL388_RS03365	COG0745	RESPONSE REGULATOR receiver
EL388_RS03370	COG0835	chemotaxis
EL388_RS03370	COG0784	Response regulator, receiver
EL388_RS03375	COG0784	Response regulator, receiver
EL388_RS03375	COG0835	chemotaxis
EL388_RS03385	COG3852	Histidine kinase
EL388_RS03395	COG1677	Flagellar hook-basal body complex protein FliE
EL388_RS03410	COG1317	bacterial-type flagellum organization
EL388_RS03415	COG1157	protein secretion by the type III secretion system
EL388_RS03450	COG3278	Belongs to the heme-copper respiratory oxidase family
EL388_RS03460	COG2217	Heavy metal translocating P-type atpase
EL388_RS03465	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EL388_RS03470	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EL388_RS03485	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EL388_RS03495	COG3634	alkyl hydroperoxide reductase activity
EL388_RS03510	COG0840	transmembrane signaling receptor activity
EL388_RS03515	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EL388_RS03525	COG0802	atpase or kinase
EL388_RS03530	COG0860	N-Acetylmuramoyl-L-alanine amidase
EL388_RS03540	COG2197	response regulator
EL388_RS03545	COG0123	including yeast histone deacetylase and acetoin utilization protein
EL388_RS03550	COG1042	CoA-binding domain protein
EL388_RS03550	COG0045	succinate-CoA ligase (ADP-forming) activity
EL388_RS03550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EL388_RS03555	COG1648	precorrin-2 dehydrogenase activity
EL388_RS03555	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EL388_RS03565	COG1797	cobyrinic acid a,c-diamide synthase activity
EL388_RS03570	COG3301	Polysulphide reductase, NrfD
EL388_RS03600	COG2920	part of a sulfur-relay system
EL388_RS03610	COG2923	Belongs to the DsrF TusC family
EL388_RS03615	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EL388_RS03620	COG2221	Nitrite and sulphite reductase 4Fe-4S
EL388_RS03625	COG2221	Nitrite and sulphite reductase 4Fe-4S
EL388_RS03640	COG2920	part of a sulfur-relay system
EL388_RS03665	COG2010	Cytochrome c
EL388_RS03680	COG2010	Cytochrome c
EL388_RS03705	COG0535	radical SAM domain protein
EL388_RS03730	COG2070	2-Nitropropane dioxygenase
EL388_RS03740	COG3300	MHYT domain
EL388_RS03740	COG5001	Diguanylate cyclase
EL388_RS03745	COG2197	response regulator
EL388_RS03750	COG3850	Histidine kinase
EL388_RS03765	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EL388_RS03775	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EL388_RS03780	COG2181	nitrate reductase activity
EL388_RS03795	COG1242	4 iron, 4 sulfur cluster binding
EL388_RS03800	COG0826	peptidase U32
EL388_RS03805	COG0826	peptidase U32
EL388_RS03810	COG3154	lipid carrier protein
EL388_RS03835	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EL388_RS03855	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EL388_RS03860	COG1570	exodeoxyribonuclease VII activity
EL388_RS03865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EL388_RS03870	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EL388_RS03885	COG0137	argininosuccinate synthase activity
EL388_RS03890	COG3123	guanosine phosphorylase activity
EL388_RS03900	COG1666	GTP binding
EL388_RS03910	COG0475	glutathione-regulated potassium exporter activity
EL388_RS03910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EL388_RS03920	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EL388_RS03925	COG0840	transmembrane signaling receptor activity
EL388_RS03930	COG0500	methyltransferase
EL388_RS03935	COG2183	response to ionizing radiation
EL388_RS03945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EL388_RS03950	COG1490	D-aminoacyl-tRNA deacylase activity
EL388_RS03960	COG1902	pentaerythritol trinitrate reductase activity
EL388_RS03970	COG0783	Belongs to the Dps family
EL388_RS03985	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EL388_RS04005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EL388_RS04020	COG2951	lytic endotransglycosylase activity
EL388_RS04045	COG2391	methyltransferase activity
EL388_RS04055	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
EL388_RS04080	COG1187	pseudouridine synthase activity
EL388_RS04090	COG0531	amino acid
EL388_RS04095	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EL388_RS04100	COG0058	SHG alpha-glucan phosphorylase activity
EL388_RS04145	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EL388_RS04170	COG3588	fructose-bisphosphate aldolase
EL388_RS04175	COG0028	Belongs to the TPP enzyme family
EL388_RS04185	COG3177	Filamentation induced by cAMP protein fic
EL388_RS04205	COG0210	DNA helicase
EL388_RS04210	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EL388_RS04245	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EL388_RS04255	COG2161	toxin-antitoxin pair type II binding
EL388_RS04300	COG2827	Endonuclease containing a URI domain
EL388_RS04310	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EL388_RS04320	COG2716	regulation of RNA biosynthetic process
EL388_RS04330	COG0583	DNA-binding transcription factor activity
EL388_RS04340	COG2204	response regulator
EL388_RS04345	COG4191	Histidine kinase
EL388_RS04355	COG0243	molybdopterin cofactor binding
EL388_RS04360	COG0437	4 iron, 4 sulfur cluster binding
EL388_RS04435	COG0640	Transcriptional regulator
EL388_RS04460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EL388_RS04465	COG0798	PFAM Bile acid sodium symporter
EL388_RS04485	COG2205	protein histidine kinase activity
EL388_RS04485	COG3437	response regulator, receiver
EL388_RS04485	COG3850	Histidine kinase
EL388_RS04485	COG4999	Histidine kinase
EL388_RS04495	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EL388_RS04505	COG0247	lactate metabolic process
EL388_RS04530	COG0375	protein maturation
EL388_RS04535	COG0298	carbon dioxide binding
EL388_RS04540	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
EL388_RS04545	COG0437	4 iron, 4 sulfur cluster binding
EL388_RS04550	COG5557	Pfam Polysulphide reductase, NrfD
EL388_RS04555	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
EL388_RS04565	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EL388_RS04575	COG2860	membrane
EL388_RS04580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EL388_RS04595	COG0778	Nitroreductase
EL388_RS04600	COG0243	molybdopterin cofactor binding
EL388_RS04605	COG0723	plastoquinol--plastocyanin reductase activity
EL388_RS04610	COG0330	HflC and HflK could
EL388_RS04620	COG1253	flavin adenine dinucleotide binding
EL388_RS04640	COG0277	FAD linked oxidase domain protein
EL388_RS04645	COG0277	FAD linked oxidase domain protein
EL388_RS04650	COG0247	lactate metabolic process
EL388_RS04660	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EL388_RS04680	COG0154	amidase activity
EL388_RS04690	COG2084	Dehydrogenase
EL388_RS04695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EL388_RS04700	COG0861	Integral membrane protein TerC family
EL388_RS04705	COG0589	response to stress
EL388_RS04710	COG1929	Belongs to the glycerate kinase type-1 family
EL388_RS04715	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EL388_RS04730	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EL388_RS04735	COG0693	protein deglycase activity
EL388_RS04755	COG2154	pterin-4-alpha-carbinolamine dehydratase
EL388_RS04765	COG0501	Belongs to the peptidase M48B family
EL388_RS04770	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EL388_RS04780	COG0297	glycogen (starch) synthase activity
EL388_RS04785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL388_RS04785	COG2205	protein histidine kinase activity
EL388_RS04795	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EL388_RS04800	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EL388_RS04810	COG5002	protein histidine kinase activity
EL388_RS04810	COG2205	protein histidine kinase activity
EL388_RS04810	COG0784	Response regulator, receiver
EL388_RS04815	COG1331	Highly conserved protein containing a thioredoxin domain
EL388_RS04825	COG0723	plastoquinol--plastocyanin reductase activity
EL388_RS04830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EL388_RS04835	COG2857	Cytochrome c1
EL388_RS04840	COG0625	glutathione transferase activity
EL388_RS04880	COG2346	COG2346, Truncated hemoglobins
EL388_RS04885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EL388_RS04895	COG1566	PFAM secretion protein HlyD family protein
EL388_RS04900	COG1136	(ABC) transporter
EL388_RS04900	COG0577	efflux transmembrane transporter activity
EL388_RS04905	COG1136	(ABC) transporter
EL388_RS04915	COG0300	oxidoreductase activity
EL388_RS04925	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EL388_RS04930	COG0693	protein deglycase activity
EL388_RS04935	COG0205	6-phosphofructokinase activity
EL388_RS04940	COG0826	peptidase U32
EL388_RS04960	COG0700	Nucleoside recognition
EL388_RS04975	COG3025	triphosphatase activity
EL388_RS04990	COG0243	molybdopterin cofactor binding
EL388_RS04995	COG0437	4 iron, 4 sulfur cluster binding
EL388_RS05000	COG0348	domain, Protein
EL388_RS05005	COG3043	anaerobic respiration
EL388_RS05020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EL388_RS05035	COG0504	CTP synthase activity
EL388_RS05040	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EL388_RS05045	COG0148	phosphopyruvate hydratase activity
EL388_RS05050	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EL388_RS05060	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EL388_RS05070	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EL388_RS05080	COG2201	protein-glutamate methylesterase activity
EL388_RS05085	COG0047	phosphoribosylformylglycinamidine synthase activity
EL388_RS05085	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EL388_RS05090	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EL388_RS05095	COG1217	gtp-binding protein TYPA
EL388_RS05105	COG3118	belongs to the thioredoxin family
EL388_RS05110	COG0436	Aminotransferase
EL388_RS05125	COG2850	peptidyl-arginine hydroxylation
EL388_RS05135	COG0825	malonyl-CoA metabolic process
EL388_RS05140	COG0037	tRNA processing
EL388_RS05150	COG0105	UTP biosynthetic process
EL388_RS05155	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EL388_RS05170	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EL388_RS05175	COG0124	histidyl-tRNA synthetase
EL388_RS05190	COG1160	GTP binding
EL388_RS05200	COG1923	regulation of RNA biosynthetic process
EL388_RS05205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EL388_RS05210	COG0330	HflC and HflK could
EL388_RS05215	COG0330	HflC and HflK could
EL388_RS05225	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EL388_RS05230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EL388_RS05240	COG0557	exoribonuclease II activity
EL388_RS05245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EL388_RS05250	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EL388_RS05255	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EL388_RS05270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EL388_RS05285	COG1086	Polysaccharide biosynthesis protein
EL388_RS05290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EL388_RS05295	COG2089	acid synthase
EL388_RS05300	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EL388_RS05305	COG0107	imidazoleglycerol-phosphate synthase activity
EL388_RS05315	COG1083	cytidylyl-transferase
EL388_RS05325	COG2089	acid synthase
EL388_RS05335	COG1216	Glycosyl transferase, family 2
EL388_RS05335	COG0438	transferase activity, transferring glycosyl groups
EL388_RS05350	COG2257	FlhB HrpN YscU SpaS Family
EL388_RS05355	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EL388_RS05360	COG0024	Methionine aminopeptidase
EL388_RS05365	COG1254	Belongs to the acylphosphatase family
EL388_RS05370	COG1047	Peptidyl-prolyl cis-trans
EL388_RS05375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL388_RS05375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL388_RS05385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EL388_RS05395	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EL388_RS05400	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EL388_RS05405	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EL388_RS05410	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EL388_RS05420	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EL388_RS05425	COG0072	phenylalanine-tRNA ligase activity
EL388_RS05425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL388_RS05430	COG0776	regulation of translation
EL388_RS05445	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EL388_RS05450	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EL388_RS05465	COG1011	Hydrolase
EL388_RS05475	COG0436	Aminotransferase
EL388_RS05490	COG3706	GGDEF domain
EL388_RS05520	COG0542	response to heat
EL388_RS05530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL388_RS05535	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
EL388_RS05550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EL388_RS05570	COG0281	malic enzyme
EL388_RS05585	COG1053	succinate dehydrogenase
EL388_RS05590	COG0840	transmembrane signaling receptor activity
EL388_RS05590	COG3290	protein histidine kinase activity
EL388_RS05595	COG0840	transmembrane signaling receptor activity
EL388_RS05620	COG1230	cation diffusion facilitator family transporter
EL388_RS05655	COG3093	addiction module antidote protein HigA
EL388_RS05660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EL388_RS05670	COG0372	Belongs to the citrate synthase family
EL388_RS05675	COG0567	Dehydrogenase, E1 component
EL388_RS05680	COG0642	Histidine kinase
EL388_RS05710	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EL388_RS05715	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EL388_RS05720	COG2205	protein histidine kinase activity
EL388_RS05720	COG4999	Histidine kinase
EL388_RS05720	COG3850	Histidine kinase
EL388_RS05720	COG3437	response regulator, receiver
EL388_RS05725	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EL388_RS05740	COG3842	ATPase activity
EL388_RS05745	COG1175	transmembrane transport
EL388_RS05785	COG4774	siderophore transport
EL388_RS05790	COG3128	pkhd-type hydroxylase
EL388_RS05800	COG1858	cytochrome C peroxidase
EL388_RS05810	COG0791	NLP P60 protein
EL388_RS05825	COG0288	reversible hydration of carbon dioxide
EL388_RS05830	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EL388_RS05835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EL388_RS05850	COG0287	Prephenate dehydrogenase
EL388_RS05865	COG0776	regulation of translation
EL388_RS05875	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EL388_RS05880	COG0284	orotidine-5'-phosphate decarboxylase activity
EL388_RS05905	COG0424	maF-like protein
EL388_RS05910	COG0511	ligase activity, forming carbon-carbon bonds
EL388_RS05910	COG5016	pyruvate
EL388_RS05915	COG0439	Biotin carboxylase
EL388_RS05920	COG1399	metal-binding, possibly nucleic acid-binding protein
EL388_RS05925	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EL388_RS05930	COG0416	fatty acid biosynthetic process
EL388_RS05935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EL388_RS05945	COG1028	Short-chain dehydrogenase reductase Sdr
EL388_RS05950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EL388_RS05955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EL388_RS05960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EL388_RS05965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EL388_RS05970	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EL388_RS05975	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EL388_RS05990	COG0084	hydrolase, TatD family'
EL388_RS06010	COG0542	response to heat
EL388_RS06015	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EL388_RS06020	COG1278	Cold shock
EL388_RS06040	COG0402	S-adenosylhomocysteine deaminase activity
EL388_RS06050	COG1923	regulation of RNA biosynthetic process
EL388_RS06060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EL388_RS06065	COG0271	Belongs to the BolA IbaG family
EL388_RS06070	COG2350	Protein conserved in bacteria
EL388_RS06075	COG2917	probably involved in intracellular septation
EL388_RS06080	COG0613	PHP domain protein
EL388_RS06085	COG0009	L-threonylcarbamoyladenylate synthase
EL388_RS06090	COG1994	Peptidase M50
EL388_RS06095	COG0180	Tryptophanyl-tRNA synthetase
EL388_RS06105	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EL388_RS06110	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EL388_RS06115	COG1187	pseudouridine synthase activity
EL388_RS06120	COG0668	transmembrane transport
EL388_RS06130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EL388_RS06135	COG1393	Belongs to the ArsC family
EL388_RS06145	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EL388_RS06160	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
EL388_RS06165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EL388_RS06175	COG2914	Belongs to the UPF0125 (RnfH) family
EL388_RS06190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EL388_RS06190	COG0519	Catalyzes the synthesis of GMP from XMP
EL388_RS06200	COG1136	(ABC) transporter
EL388_RS06220	COG1309	transcriptional regulator
EL388_RS06275	COG0601	transmembrane transport
EL388_RS06280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EL388_RS06290	COG1388	LysM domain
EL388_RS06290	COG0741	lytic transglycosylase activity
EL388_RS06300	COG2226	methyltransferase
EL388_RS06305	COG0328	RNA-DNA hybrid ribonuclease activity
EL388_RS06325	COG2747	anti-sigma28 factor FlgM
EL388_RS06340	COG1815	bacterial-type flagellum-dependent cell motility
EL388_RS06345	COG1558	bacterial-type flagellum-dependent cell motility
EL388_RS06350	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EL388_RS06355	COG1749	Flagellar hook protein flgE
EL388_RS06360	COG4786	Flagellar basal body rod
EL388_RS06370	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EL388_RS06375	COG1706	bacterial-type flagellum-dependent cell motility
EL388_RS06380	COG3951	Flagellar rod assembly protein muramidase FlgJ
EL388_RS06380	COG1705	Flagellar rod assembly protein muramidase FlgJ
EL388_RS06385	COG1256	bacterial-type flagellum assembly
EL388_RS06385	COG4786	Flagellar basal body rod
EL388_RS06390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EL388_RS06395	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EL388_RS06415	COG1073	alpha beta
EL388_RS06430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EL388_RS06475	COG1355	regulation of microtubule-based process
EL388_RS06480	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EL388_RS06485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EL388_RS06495	COG0564	pseudouridine synthase activity
EL388_RS06510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EL388_RS06520	COG0482	sulfurtransferase activity
EL388_RS06530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EL388_RS06565	COG0582	viral genome integration into host DNA
EL388_RS06580	COG0436	Aminotransferase
EL388_RS06585	COG0556	nucleotide-excision repair
EL388_RS06590	COG2920	part of a sulfur-relay system
EL388_RS06600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EL388_RS06605	COG1530	ribonuclease E activity
EL388_RS06610	COG0564	pseudouridine synthase activity
EL388_RS06625	COG0616	signal peptide processing
EL388_RS06625	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EL388_RS06635	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EL388_RS06640	COG0443	Heat shock 70 kDa protein
EL388_RS06645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EL388_RS06655	COG0475	glutathione-regulated potassium exporter activity
EL388_RS06655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EL388_RS06675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EL388_RS06680	COG0501	Belongs to the peptidase M48B family
EL388_RS06695	COG0071	Belongs to the small heat shock protein (HSP20) family
EL388_RS06700	COG0071	Belongs to the small heat shock protein (HSP20) family
EL388_RS06710	COG2920	part of a sulfur-relay system
EL388_RS06715	COG0484	heat shock protein binding
EL388_RS06725	COG0508	dehydrogenase complex catalyzes the overall conversion of
EL388_RS06730	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EL388_RS06735	COG1984	allophanate hydrolase subunit 2
EL388_RS06745	COG2171	N-acyltransferase activity
EL388_RS06750	COG0436	Aminotransferase
EL388_RS06775	COG1070	Carbohydrate kinase
EL388_RS06780	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EL388_RS06790	COG5001	Diguanylate cyclase
EL388_RS06800	COG1199	ATP-dependent helicase activity
EL388_RS06825	COG1704	LemA family
EL388_RS06830	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EL388_RS06840	COG0477	Major facilitator Superfamily
EL388_RS06845	COG0583	DNA-binding transcription factor activity
EL388_RS06855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EL388_RS06860	COG0546	phosphoglycolate phosphatase activity
EL388_RS06980	COG1475	DNA binding
EL388_RS07140	COG0326	Molecular chaperone. Has ATPase activity
EL388_RS07150	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EL388_RS07155	COG0210	DNA helicase
EL388_RS07195	COG1132	(ABC) transporter
EL388_RS07200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EL388_RS07200	COG0189	ligase activity
EL388_RS07205	COG0189	ligase activity
EL388_RS07205	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EL388_RS07210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EL388_RS07220	COG2205	protein histidine kinase activity
EL388_RS07220	COG2202	Pas domain
EL388_RS07225	COG2202	Pas domain
EL388_RS07225	COG2205	protein histidine kinase activity
EL388_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
EL388_RS07245	COG0446	pyridine nucleotide-disulphide oxidoreductase
EL388_RS07245	COG1902	pentaerythritol trinitrate reductase activity
EL388_RS07255	COG1562	ergosterol biosynthetic process
EL388_RS07265	COG3193	protein, possibly involved in utilization of glycolate and propanediol
EL388_RS07270	COG0544	peptidyl-prolyl cis-trans isomerase activity
EL388_RS07275	COG0740	serine-type endopeptidase activity
EL388_RS07280	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EL388_RS07285	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EL388_RS07305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EL388_RS07310	COG1136	(ABC) transporter
EL388_RS07310	COG0577	efflux transmembrane transporter activity
EL388_RS07315	COG0577	efflux transmembrane transporter activity
EL388_RS07315	COG1136	(ABC) transporter
EL388_RS07320	COG1136	(ABC) transporter
EL388_RS07320	COG0577	efflux transmembrane transporter activity
EL388_RS07345	COG0492	ferredoxin-NADP+ reductase activity
EL388_RS07350	COG1674	ftsk spoiiie
EL388_RS07355	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EL388_RS07370	COG2608	mercury ion transmembrane transporter activity
EL388_RS07380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EL388_RS07385	COG0052	Belongs to the universal ribosomal protein uS2 family
EL388_RS07390	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EL388_RS07395	COG0528	UMP kinase activity
EL388_RS07400	COG0233	cytoplasmic translational termination
EL388_RS07405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EL388_RS07415	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EL388_RS07430	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EL388_RS07435	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EL388_RS07440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EL388_RS07445	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EL388_RS07450	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EL388_RS07455	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EL388_RS07470	COG1360	Flagellar Motor Protein
EL388_RS07490	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EL388_RS07495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EL388_RS07535	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EL388_RS07540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EL388_RS07545	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EL388_RS07555	COG0398	Pfam SNARE associated Golgi protein
EL388_RS07560	COG0004	ammonium transporteR
EL388_RS07565	COG0805	protein transport
EL388_RS07570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EL388_RS07575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EL388_RS07585	COG0140	phosphoribosyl-ATP diphosphatase activity
EL388_RS07590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EL388_RS07595	COG0107	imidazoleglycerol-phosphate synthase activity
EL388_RS07600	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EL388_RS07605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EL388_RS07610	COG0131	Imidazoleglycerol-phosphate dehydratase
EL388_RS07615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EL388_RS07620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EL388_RS07625	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EL388_RS07630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EL388_RS07640	COG0842	Transport permease protein
EL388_RS07645	COG1131	(ABC) transporter
EL388_RS07660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EL388_RS07665	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EL388_RS07670	COG1127	ABC transporter
EL388_RS07680	COG0215	cysteine-tRNA ligase activity
EL388_RS07685	COG0514	ATP-dependent DNA helicase (RecQ)
EL388_RS07720	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EL388_RS07740	COG1286	toxin biosynthetic process
EL388_RS07750	COG0285	dihydrofolate synthase activity
EL388_RS07755	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EL388_RS07760	COG0159	tryptophan synthase activity
EL388_RS07765	COG0133	tryptophan synthase activity
EL388_RS07770	COG0135	phosphoribosylanthranilate isomerase activity
EL388_RS07775	COG0101	tRNA pseudouridine synthase activity
EL388_RS07800	COG0473	3-isopropylmalate dehydrogenase activity
EL388_RS07805	COG0066	3-isopropylmalate dehydratase activity
EL388_RS07815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EL388_RS07830	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EL388_RS07840	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EL388_RS07845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EL388_RS07850	COG0022	dehydrogenase e1 component
EL388_RS07850	COG0508	dehydrogenase complex catalyzes the overall conversion of
EL388_RS07860	COG4566	intracellular signal transduction
EL388_RS07865	COG0488	(ABC) transporter
EL388_RS07870	COG2900	Belongs to the SlyX family
EL388_RS07880	COG3706	GGDEF domain
EL388_RS07910	COG0686	Belongs to the AlaDH PNT family
EL388_RS07925	COG4657	Part of a membrane complex involved in electron transport
EL388_RS07930	COG2878	Part of a membrane complex involved in electron transport
EL388_RS07950	COG4660	Part of a membrane complex involved in electron transport
EL388_RS07955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EL388_RS07970	COG1192	Involved in chromosome partitioning
EL388_RS07980	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EL388_RS07985	COG3174	membrane
EL388_RS07990	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EL388_RS08015	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EL388_RS08035	COG0588	phosphoglycerate mutase activity
EL388_RS08040	COG0406	alpha-ribazole phosphatase activity
EL388_RS08045	COG0714	Associated with various cellular activities
EL388_RS08065	COG0778	Nitroreductase
EL388_RS08070	COG1733	regulation of RNA biosynthetic process
EL388_RS08075	COG2217	Heavy metal translocating P-type atpase
EL388_RS08080	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EL388_RS08090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL388_RS08100	COG3864	Putative metallopeptidase domain
EL388_RS08105	COG0542	response to heat
EL388_RS08115	COG0745	RESPONSE REGULATOR receiver
EL388_RS08125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EL388_RS08125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EL388_RS08135	COG2226	methyltransferase
EL388_RS08140	COG0326	Molecular chaperone. Has ATPase activity
EL388_RS08145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EL388_RS08150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EL388_RS08155	COG0735	belongs to the Fur family
EL388_RS08160	COG0497	DNA recombination
EL388_RS08165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EL388_RS08170	COG1420	regulation of RNA biosynthetic process
EL388_RS08175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EL388_RS08185	COG0446	pyridine nucleotide-disulphide oxidoreductase
EL388_RS08190	COG1234	tRNA 3'-trailer cleavage
EL388_RS08200	COG4783	chaperone-mediated protein folding
EL388_RS08210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EL388_RS08235	COG1047	Peptidyl-prolyl cis-trans
EL388_RS08245	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EL388_RS08250	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EL388_RS08255	COG0166	Belongs to the GPI family
EL388_RS08285	COG1136	(ABC) transporter
EL388_RS08295	COG0432	Pfam Uncharacterised protein family UPF0047
EL388_RS08310	COG4106	trans-aconitate 2-methyltransferase activity
EL388_RS08315	COG5001	Diguanylate cyclase
EL388_RS08315	COG3300	MHYT domain
EL388_RS08320	COG2205	protein histidine kinase activity
EL388_RS08340	COG3437	response regulator, receiver
EL388_RS08345	COG0167	dihydroorotate dehydrogenase activity
EL388_RS08350	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EL388_RS08350	COG1013	pyruvate-flavodoxin oxidoreductase activity
EL388_RS08350	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EL388_RS08350	COG0674	pyruvate-flavodoxin oxidoreductase activity
EL388_RS08355	COG4206	TonB-dependent receptor
EL388_RS08370	COG1515	deoxyribonuclease V activity
EL388_RS08380	COG1628	Protein of unknown function DUF99
EL388_RS08390	COG1234	tRNA 3'-trailer cleavage
EL388_RS08405	COG5001	Diguanylate cyclase
EL388_RS08405	COG5002	protein histidine kinase activity
EL388_RS08410	COG0513	Belongs to the DEAD box helicase family
EL388_RS08430	COG0309	Hydrogenase expression formation protein (HypE)
EL388_RS08440	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EL388_RS08470	COG0697	spore germination
EL388_RS08475	COG1322	Protein conserved in bacteria
EL388_RS08480	COG0577	efflux transmembrane transporter activity
EL388_RS08480	COG1136	(ABC) transporter
EL388_RS08485	COG0577	efflux transmembrane transporter activity
EL388_RS08485	COG1136	(ABC) transporter
EL388_RS08490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL388_RS08495	COG3842	ATPase activity
EL388_RS08500	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EL388_RS08520	COG0714	Associated with various cellular activities
EL388_RS08555	COG3258	Cytochrome c
EL388_RS08575	COG4783	chaperone-mediated protein folding
EL388_RS08580	COG0315	cyclic pyranopterin monophosphate synthase activity
EL388_RS08585	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EL388_RS08600	COG2920	part of a sulfur-relay system
EL388_RS08610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EL388_RS08615	COG1032	radical SAM domain protein
EL388_RS08620	COG0121	glutamine amidotransferase
EL388_RS08630	COG0788	formyltetrahydrofolate deformylase activity
EL388_RS08640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EL388_RS08640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EL388_RS08645	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EL388_RS08665	COG0727	PFAM Uncharacterised protein family (UPF0153)
EL388_RS08670	COG4681	YaeQ
EL388_RS08685	COG0784	Response regulator, receiver
EL388_RS08685	COG2205	protein histidine kinase activity
EL388_RS08685	COG5002	protein histidine kinase activity
EL388_RS08700	COG2010	Cytochrome c
EL388_RS08715	COG1752	Esterase of the alpha-beta hydrolase superfamily
EL388_RS08720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EL388_RS08775	COG3012	SEC-C Motif Domain Protein
EL388_RS08785	COG1278	Cold shock
EL388_RS08790	COG1752	Esterase of the alpha-beta hydrolase superfamily
EL388_RS08800	COG1473	amidohydrolase
EL388_RS08810	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EL388_RS08825	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EL388_RS08825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EL388_RS08840	COG2210	Belongs to the sulfur carrier protein TusA family
EL388_RS08845	COG0425	Belongs to the sulfur carrier protein TusA family
EL388_RS08850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EL388_RS08855	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EL388_RS08860	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EL388_RS08865	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EL388_RS08865	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EL388_RS08915	COG0142	geranyltranstransferase activity
EL388_RS08930	COG2210	Belongs to the sulfur carrier protein TusA family
EL388_RS08935	COG0702	epimerase
EL388_RS08945	COG0302	gtp cyclohydrolase
EL388_RS08950	COG3647	Membrane
EL388_RS08965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EL388_RS08975	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EL388_RS08985	COG0631	protein serine/threonine phosphatase activity
EL388_RS08990	COG1357	PFAM Pentapeptide repeats (8 copies)
EL388_RS08990	COG0515	serine threonine protein kinase
EL388_RS08995	COG1561	YicC-like family, N-terminal region
EL388_RS09000	COG0582	viral genome integration into host DNA
EL388_RS09040	COG0194	GDP metabolic process
EL388_RS09045	COG1758	RNA polymerase activity
EL388_RS09050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EL388_RS09065	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EL388_RS09070	COG3161	chorismate lyase activity
EL388_RS09075	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EL388_RS09080	COG0521	Mo-molybdopterin cofactor biosynthetic process
EL388_RS09085	COG2199	diguanylate cyclase activity
EL388_RS09085	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EL388_RS09090	COG0463	Glycosyl transferase, family 2
EL388_RS09095	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EL388_RS09100	COG0671	phosphoesterase, PA-phosphatase related
EL388_RS09105	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EL388_RS09120	COG0501	Belongs to the peptidase M48B family
EL388_RS09125	COG0778	Nitroreductase
EL388_RS09130	COG2833	Protein of unknown function (DUF455)
EL388_RS09135	COG0363	glucosamine-6-phosphate deaminase activity
EL388_RS09145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EL388_RS09150	COG0670	Belongs to the BI1 family
EL388_RS09155	COG0527	aspartate kinase activity
EL388_RS09180	COG1940	carbohydrate kinase activity
EL388_RS09195	COG0277	FAD linked oxidase domain protein
EL388_RS09200	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EL388_RS09210	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EL388_RS09210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EL388_RS09215	COG0058	SHG alpha-glucan phosphorylase activity
EL388_RS09220	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EL388_RS09225	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EL388_RS09235	COG0488	(ABC) transporter
EL388_RS09280	COG2274	protein secretion by the type I secretion system
EL388_RS09285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EL388_RS09300	COG0546	phosphoglycolate phosphatase activity
EL388_RS09310	COG2967	ApaG domain
EL388_RS09320	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EL388_RS09340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EL388_RS09345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EL388_RS09350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EL388_RS09355	COG0006	proline dipeptidase activity
EL388_RS09370	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EL388_RS09375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EL388_RS09380	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EL388_RS09385	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EL388_RS09415	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EL388_RS09425	COG0751	glycine-tRNA ligase activity
EL388_RS09430	COG0752	glycyl-tRNA synthetase alpha subunit
EL388_RS09455	COG0741	lytic transglycosylase activity
EL388_RS09455	COG1196	nuclear chromosome segregation
EL388_RS09455	COG0739	heme binding
EL388_RS09460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EL388_RS09465	COG2239	Acts as a magnesium transporter
EL388_RS09480	COG0739	heme binding
EL388_RS09485	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EL388_RS09490	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EL388_RS09495	COG0237	dephospho-CoA kinase activity
EL388_RS09500	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EL388_RS09515	COG4536	flavin adenine dinucleotide binding
EL388_RS09545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EL388_RS09550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EL388_RS09565	COG2022	thiamine diphosphate biosynthetic process
EL388_RS09570	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EL388_RS09575	COG0446	pyridine nucleotide-disulphide oxidoreductase
EL388_RS09590	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EL388_RS09605	COG2885	chlorophyll binding
EL388_RS09620	COG0312	modulator of DNA gyrase
EL388_RS09625	COG3028	Belongs to the UPF0307 family
EL388_RS09630	COG3302	dmso reductase anchor subunit
EL388_RS09635	COG0437	4 iron, 4 sulfur cluster binding
EL388_RS09640	COG0243	molybdopterin cofactor binding
EL388_RS09650	COG5265	(ABC) transporter
EL388_RS09695	COG1643	Atp-dependent helicase
EL388_RS09705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EL388_RS09715	COG0084	hydrolase, TatD family'
EL388_RS09720	COG0475	glutathione-regulated potassium exporter activity
EL388_RS09730	COG1846	Transcriptional regulator
EL388_RS09745	COG3263	regulation of cellular component size
EL388_RS09750	COG0589	response to stress
EL388_RS09760	COG0617	tRNA 3'-terminal CCA addition
EL388_RS09770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EL388_RS09775	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EL388_RS09785	COG0484	heat shock protein binding
EL388_RS09790	COG1748	Saccharopine dehydrogenase
EL388_RS09830	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EL388_RS09835	COG0316	Belongs to the HesB IscA family
EL388_RS09840	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EL388_RS09845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EL388_RS09850	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EL388_RS09855	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EL388_RS09860	COG1765	OsmC-like protein
EL388_RS09870	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EL388_RS09900	COG1660	Displays ATPase and GTPase activities
EL388_RS09905	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EL388_RS09915	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EL388_RS09920	COG1137	ATPase activity
EL388_RS09925	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EL388_RS09935	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EL388_RS09950	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EL388_RS09955	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EL388_RS09960	COG1381	Involved in DNA repair and RecF pathway recombination
EL388_RS09965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EL388_RS09970	COG0571	ribonuclease III activity
EL388_RS09980	COG0681	Belongs to the peptidase S26 family
EL388_RS09985	COG0481	GTPase activity
EL388_RS09995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EL388_RS10020	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EL388_RS10025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EL388_RS10030	COG0795	lipopolysaccharide-transporting ATPase activity
EL388_RS10040	COG1714	RDD family
EL388_RS10045	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EL388_RS10050	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EL388_RS10055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EL388_RS10060	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EL388_RS10065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EL388_RS10095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL388_RS10105	COG1360	Flagellar Motor Protein
EL388_RS10110	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EL388_RS10130	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EL388_RS10145	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EL388_RS10150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EL388_RS10155	COG2813	Specifically methylates the guanine in position
EL388_RS10155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EL388_RS10180	COG1192	Involved in chromosome partitioning
EL388_RS10205	COG0564	pseudouridine synthase activity
EL388_RS10210	COG3706	GGDEF domain
EL388_RS10225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EL388_RS10235	COG1611	Belongs to the LOG family
EL388_RS10240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EL388_RS10240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EL388_RS10245	COG3437	response regulator, receiver
EL388_RS10265	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EL388_RS10270	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EL388_RS10275	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EL388_RS10280	COG0509	glycine decarboxylation via glycine cleavage system
EL388_RS10285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EL388_RS10290	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EL388_RS10300	COG2264	protein methyltransferase activity
EL388_RS10305	COG0439	Biotin carboxylase
EL388_RS10310	COG0511	ligase activity, forming carbon-carbon bonds
EL388_RS10315	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EL388_RS10350	COG0463	Glycosyl transferase, family 2
EL388_RS10375	COG2239	Acts as a magnesium transporter
EL388_RS10380	COG0840	transmembrane signaling receptor activity
EL388_RS10385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EL388_RS10390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EL388_RS10395	COG0174	glutamine synthetase
EL388_RS10405	COG3852	Histidine kinase
EL388_RS10440	COG0443	Heat shock 70 kDa protein
EL388_RS10445	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EL388_RS10455	COG0822	iron-sulfur transferase activity
EL388_RS10460	COG1104	cysteine desulfurase activity
EL388_RS10475	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EL388_RS10480	COG0483	inositol monophosphate 1-phosphatase activity
EL388_RS10490	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EL388_RS10530	COG4115	mRNA cleavage
EL388_RS10535	COG2161	toxin-antitoxin pair type II binding
EL388_RS10540	COG1007	ATP synthesis coupled electron transport
EL388_RS10555	COG0713	ATP synthesis coupled electron transport
EL388_RS10560	COG0839	Belongs to the complex I subunit 6 family
EL388_RS10565	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EL388_RS10570	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EL388_RS10575	COG1034	ATP synthesis coupled electron transport
EL388_RS10585	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EL388_RS10590	COG0649	NAD binding
EL388_RS10600	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EL388_RS10605	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EL388_RS10620	COG0149	triose-phosphate isomerase activity
EL388_RS10630	COG0469	pyruvate kinase activity
EL388_RS10635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EL388_RS10640	COG0581	inorganic phosphate transmembrane transporter activity
EL388_RS10645	COG0573	inorganic phosphate transmembrane transporter activity
EL388_RS10650	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EL388_RS10660	COG0438	transferase activity, transferring glycosyl groups
EL388_RS10665	COG0438	transferase activity, transferring glycosyl groups
EL388_RS10675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EL388_RS10680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EL388_RS10690	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EL388_RS10695	COG1534	Rna-binding protein
EL388_RS10705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EL388_RS10710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EL388_RS10715	COG0505	Belongs to the CarA family
EL388_RS10750	COG1454	alcohol dehydrogenase
EL388_RS10755	COG2137	regulation of response to DNA damage stimulus
EL388_RS10760	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EL388_RS10770	COG1546	Belongs to the CinA family
EL388_RS10775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EL388_RS10780	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EL388_RS10785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EL388_RS10790	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EL388_RS10805	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EL388_RS10805	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EL388_RS10810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EL388_RS10815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EL388_RS10820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL388_RS10850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EL388_RS10855	COG3002	Belongs to the UPF0753 family
EL388_RS10865	COG0659	secondary active sulfate transmembrane transporter activity
EL388_RS10870	COG2204	response regulator
EL388_RS10875	COG4191	Histidine kinase
EL388_RS10890	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EL388_RS10890	COG0617	tRNA 3'-terminal CCA addition
EL388_RS10890	COG0517	IMP dehydrogenase activity
EL388_RS10910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EL388_RS10910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EL388_RS10930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EL388_RS10940	COG0861	Integral membrane protein TerC family
EL388_RS10945	COG0501	Belongs to the peptidase M48B family
EL388_RS10950	COG0583	DNA-binding transcription factor activity
EL388_RS10980	COG1192	Involved in chromosome partitioning
EL388_RS10995	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EL388_RS11000	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EL388_RS11005	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EL388_RS11030	COG0583	DNA-binding transcription factor activity
EL388_RS11060	COG4451	ribulose bisphosphate carboxylase, small
EL388_RS11065	COG1850	ribulose-bisphosphate carboxylase activity
EL388_RS11070	COG0583	DNA-binding transcription factor activity
EL388_RS11085	COG1850	ribulose-bisphosphate carboxylase activity
EL388_RS11090	COG0583	DNA-binding transcription factor activity
EL388_RS11095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EL388_RS11095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EL388_RS11100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EL388_RS11105	COG0668	transmembrane transport
EL388_RS11120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EL388_RS11125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EL388_RS11130	COG2003	Belongs to the UPF0758 family
EL388_RS11135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EL388_RS11175	COG0312	modulator of DNA gyrase
EL388_RS11185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EL388_RS11200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EL388_RS11205	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EL388_RS11225	COG3118	belongs to the thioredoxin family
EL388_RS11240	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EL388_RS11265	COG0339	signal peptide processing
EL388_RS11295	COG0235	Class ii aldolase
EL388_RS11300	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EL388_RS11320	COG2852	Protein conserved in bacteria
EL388_RS11335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EL388_RS11345	COG0653	protein targeting
EL388_RS11370	COG0492	ferredoxin-NADP+ reductase activity
EL388_RS11385	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EL388_RS11390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EL388_RS11395	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EL388_RS11400	COG2089	acid synthase
EL388_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
EL388_RS11410	COG1083	cytidylyl-transferase
EL388_RS11425	COG0107	imidazoleglycerol-phosphate synthase activity
EL388_RS11440	COG1215	transferase activity, transferring glycosyl groups
EL388_RS11460	COG0529	Catalyzes the synthesis of activated sulfate
EL388_RS11500	COG3347	Dehydrogenase
EL388_RS11500	COG1028	Short-chain dehydrogenase reductase Sdr
EL388_RS11505	COG1028	Short-chain dehydrogenase reductase Sdr
EL388_RS11515	COG1028	Short-chain dehydrogenase reductase Sdr
EL388_RS11520	COG1083	cytidylyl-transferase
EL388_RS11525	COG2089	acid synthase
EL388_RS11535	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EL388_RS11560	COG1538	Outer membrane efflux protein
EL388_RS11565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EL388_RS11570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EL388_RS11575	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EL388_RS11580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EL388_RS11595	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EL388_RS11600	COG1968	undecaprenyl-diphosphatase activity
EL388_RS11610	COG1773	rubredoxin
EL388_RS11615	COG0351	phosphomethylpyrimidine kinase
EL388_RS11620	COG0352	thiamine-phosphate diphosphorylase activity
EL388_RS11625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EL388_RS11640	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EL388_RS11650	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EL388_RS11655	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EL388_RS11700	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EL388_RS11715	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EL388_RS11720	COG1181	Belongs to the D-alanine--D-alanine ligase family
EL388_RS11725	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EL388_RS11730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EL388_RS11735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EL388_RS11740	COG0772	Belongs to the SEDS family
EL388_RS11745	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EL388_RS11750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EL388_RS11755	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EL388_RS11760	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EL388_RS11770	COG3116	cell division
EL388_RS11775	COG0275	rRNA processing
EL388_RS11780	COG2001	Belongs to the MraZ family
EL388_RS11790	COG0418	dihydroorotase activity
EL388_RS11795	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EL388_RS11800	COG0792	nuclease activity
EL388_RS11805	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EL388_RS11810	COG2823	Periplasmic or secreted lipoprotein
EL388_RS11815	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EL388_RS11825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EL388_RS11830	COG0676	glucose-6-phosphate 1-epimerase activity
EL388_RS11835	COG0129	dihydroxy-acid dehydratase activity
EL388_RS11850	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EL388_RS11875	COG2856	Zn peptidase
EL388_RS12025	COG0616	signal peptide processing
EL388_RS12145	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EL388_RS12195	COG5002	protein histidine kinase activity
EL388_RS12230	COG2217	Heavy metal translocating P-type atpase
EL388_RS12265	COG1216	Glycosyl transferase, family 2
EL388_RS12280	COG0438	transferase activity, transferring glycosyl groups
EL388_RS12290	COG1216	Glycosyl transferase, family 2
EL388_RS12310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EL388_RS12350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EL388_RS12365	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EL388_RS12375	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EL388_RS12385	COG0488	(ABC) transporter
EL388_RS12390	COG5001	Diguanylate cyclase
EL388_RS12400	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EL388_RS12400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EL388_RS12405	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EL388_RS12420	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EL388_RS12425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EL388_RS12430	COG0126	phosphoglycerate kinase activity
EL388_RS12435	COG0469	pyruvate kinase activity
EL388_RS12445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EL388_RS12455	COG0116	Belongs to the methyltransferase superfamily
EL388_RS12470	COG0189	ligase activity
EL388_RS12485	COG3267	Type II secretory pathway component ExeA
EL388_RS12485	COG3409	Peptidoglycan-binding domain 1 protein
EL388_RS12540	COG2165	general secretion pathway protein
EL388_RS12545	COG1459	type II secretion system
EL388_RS12550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EL388_RS12555	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EL388_RS12560	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EL388_RS12565	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EL388_RS12600	COG0640	Transcriptional regulator
EL388_RS12605	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EL388_RS12610	COG4942	peptidase
EL388_RS12615	COG0793	Belongs to the peptidase S41A family
EL388_RS12625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EL388_RS12635	COG0493	'glutamate synthase
EL388_RS12640	COG0067	glutamate synthase
EL388_RS12640	COG0070	glutamate synthase
EL388_RS12640	COG0069	glutamate synthase activity
EL388_RS12650	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EL388_RS12665	COG0745	RESPONSE REGULATOR receiver
EL388_RS12670	COG2198	Histidine kinase
EL388_RS12670	COG0643	Histidine kinase
EL388_RS12680	COG0840	transmembrane signaling receptor activity
EL388_RS12680	COG0840	transmembrane signaling receptor activity
EL388_RS12695	COG0840	transmembrane signaling receptor activity
EL388_RS12700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EL388_RS12705	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EL388_RS12710	COG2201	protein-glutamate methylesterase activity
EL388_RS12720	COG0745	RESPONSE REGULATOR receiver
EL388_RS12725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EL388_RS12730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL388_RS12735	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL388_RS12735	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL388_RS12745	COG0277	FAD linked oxidase domain protein
EL388_RS12750	COG1309	transcriptional regulator
EL388_RS12770	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EL388_RS12775	COG4535	Mg2 and Co2 transporter CorC
EL388_RS12780	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EL388_RS12785	COG1702	phosphate starvation-inducible protein PhoH
EL388_RS12805	COG1612	heme a metabolic process
EL388_RS12810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EL388_RS12815	COG1132	(ABC) transporter
EL388_RS12835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EL388_RS12875	COG1640	4-alpha-glucanotransferase
EL388_RS12880	COG1858	cytochrome C peroxidase
EL388_RS12895	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EL388_RS12900	COG0459	protein refolding
EL388_RS12905	COG4771	TonB-dependent receptor
EL388_RS12920	COG0179	Fumarylacetoacetate (FAA) hydrolase
EL388_RS12930	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EL388_RS12960	COG0745	RESPONSE REGULATOR receiver
EL388_RS12970	COG3220	belongs to the UPF0276 family
EL388_RS12990	COG2259	Doxx family
EL388_RS12995	COG0071	Belongs to the small heat shock protein (HSP20) family
EL388_RS13000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EL388_RS13020	COG0730	response to heat
EL388_RS13045	COG0762	integral membrane protein
EL388_RS13050	COG1872	DUF167
EL388_RS13055	COG1530	ribonuclease E activity
EL388_RS13060	COG0424	maF-like protein
EL388_RS13065	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EL388_RS13070	COG0004	ammonium transporteR
EL388_RS13095	COG0606	chelatase, subunit chli
EL388_RS13155	COG0606	chelatase, subunit chli
EL388_RS13175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EL388_RS13185	COG2176	DNA-directed DNA polymerase activity
EL388_RS13195	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EL388_RS13210	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EL388_RS13215	COG0513	Belongs to the DEAD box helicase family
EL388_RS13225	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EL388_RS13245	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EL388_RS13255	COG1560	Kdo2-lipid A biosynthetic process
EL388_RS13265	COG1832	CoA-binding protein
EL388_RS13270	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EL388_RS13280	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EL388_RS13285	COG0321	lipoyl(octanoyl) transferase activity
EL388_RS13300	COG2832	Protein of unknown function (DUF454)
EL388_RS13310	COG2921	Belongs to the UPF0250 family
EL388_RS13320	COG1686	Belongs to the peptidase S11 family
EL388_RS13330	COG0772	Belongs to the SEDS family
EL388_RS13335	COG0768	penicillin binding
EL388_RS13350	COG1077	Cell shape determining protein MreB Mrl
EL388_RS13355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EL388_RS13360	COG0154	amidase activity
EL388_RS13370	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EL388_RS13380	COG4251	negative regulation of phosphorylation
EL388_RS13395	COG0784	Response regulator, receiver
EL388_RS13400	COG5001	Diguanylate cyclase
EL388_RS13400	COG5002	protein histidine kinase activity
EL388_RS13405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EL388_RS13410	COG0708	Exodeoxyribonuclease III
EL388_RS13415	COG2223	nitrite transmembrane transporter activity
EL388_RS13420	COG2199	diguanylate cyclase activity
EL388_RS13420	COG2200	EAL domain
EL388_RS13420	COG2203	Gaf domain
EL388_RS13500	COG4387	Mu-like prophage protein GP36
EL388_RS13510	COG4397	Mu-like prophage major head subunit gpT
EL388_RS13525	COG2369	cell adhesion
EL388_RS13535	COG4383	Mu-like prophage protein gp29
EL388_RS13540	COG4373	Mu-like prophage FluMu protein gp28
EL388_RS13645	COG1192	Involved in chromosome partitioning
EL388_RS13650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EL388_RS13655	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EL388_RS13660	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EL388_RS13665	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EL388_RS13670	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EL388_RS13675	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EL388_RS13680	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EL388_RS13685	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EL388_RS13695	COG0356	it plays a direct role in the translocation of protons across the membrane
EL388_RS13710	COG1192	Involved in chromosome partitioning
EL388_RS13715	COG0357	Ribosomal RNA small subunit methyltransferase G
EL388_RS13720	COG0445	tRNA wobble uridine modification
EL388_RS13725	COG5002	protein histidine kinase activity
EL388_RS13725	COG5001	Diguanylate cyclase
EL388_RS13730	COG1132	(ABC) transporter
EL388_RS13740	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EL388_RS13745	COG0706	membrane insertase activity
EL388_RS13750	COG0594	ribonuclease P activity
EL388_RS13755	COG0230	Belongs to the bacterial ribosomal protein bL34 family