locus-tag	class	description
UCH003_RS00010	COG0592	DNA-directed DNA polymerase activity
UCH003_RS00015	COG0187	DNA topoisomerase II activity
UCH003_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
UCH003_RS00040	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
UCH003_RS00045	COG1194	a g-specific adenine glycosylase
UCH003_RS00050	COG2814	Major facilitator Superfamily
UCH003_RS00090	COG2095	MarC family integral membrane protein
UCH003_RS00105	COG0848	biopolymer transport protein
UCH003_RS00110	COG0811	peptide transport
UCH003_RS00130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UCH003_RS00140	COG2226	methyltransferase
UCH003_RS00155	COG0504	CTP synthase activity
UCH003_RS00160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
UCH003_RS00165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UCH003_RS00175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UCH003_RS00185	COG0243	molybdopterin cofactor binding
UCH003_RS00190	COG0437	4 iron, 4 sulfur cluster binding
UCH003_RS00240	COG0670	Belongs to the BI1 family
UCH003_RS00305	COG0315	cyclic pyranopterin monophosphate synthase activity
UCH003_RS00310	COG0724	RNA recognition motif
UCH003_RS00335	COG0746	molybdenum cofactor guanylyltransferase activity
UCH003_RS00340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
UCH003_RS00350	COG0450	alkyl hydroperoxide reductase
UCH003_RS00365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
UCH003_RS00370	COG1929	Belongs to the glycerate kinase type-1 family
UCH003_RS00385	COG0575	Belongs to the CDS family
UCH003_RS00390	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
UCH003_RS00395	COG2233	PERMEase
UCH003_RS00400	COG1115	amino acid carrier protein
UCH003_RS00405	COG1408	metallophosphoesterase
UCH003_RS00440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
UCH003_RS00450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
UCH003_RS00455	COG1987	bacterial-type flagellum assembly
UCH003_RS00460	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
UCH003_RS00465	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
UCH003_RS00470	COG0148	phosphopyruvate hydratase activity
UCH003_RS00485	COG0372	Belongs to the citrate synthase family
UCH003_RS00495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
UCH003_RS00525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UCH003_RS00540	COG2089	acid synthase
UCH003_RS00545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UCH003_RS00550	COG3980	spore coat polysaccharide biosynthesis protein
UCH003_RS00555	COG1083	cytidylyl-transferase
UCH003_RS00560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UCH003_RS00565	COG1086	Polysaccharide biosynthesis protein
UCH003_RS00570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
UCH003_RS00580	COG1073	alpha beta
UCH003_RS00585	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
UCH003_RS00595	COG3041	Addiction module toxin RelE StbE family
UCH003_RS00615	COG0717	Belongs to the dCTP deaminase family
UCH003_RS00620	COG0511	ligase activity, forming carbon-carbon bonds
UCH003_RS00625	COG0439	Biotin carboxylase
UCH003_RS00635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
UCH003_RS00640	COG0280	phosphate acetyltransferase
UCH003_RS00640	COG0281	malic enzyme
UCH003_RS00645	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
UCH003_RS00650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
UCH003_RS00655	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
UCH003_RS00660	COG0861	Integral membrane protein TerC family
UCH003_RS00665	COG1077	Cell shape determining protein MreB Mrl
UCH003_RS00680	COG1054	Belongs to the UPF0176 family
UCH003_RS00685	COG3706	GGDEF domain
UCH003_RS00695	COG0482	sulfurtransferase activity
UCH003_RS00710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
UCH003_RS00710	COG1648	precorrin-2 dehydrogenase activity
UCH003_RS00715	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UCH003_RS00725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
UCH003_RS00735	COG2895	sulfate adenylyltransferase (ATP) activity
UCH003_RS00740	COG0175	sulfate reduction
UCH003_RS00745	COG0175	sulfate reduction
UCH003_RS00755	COG0642	Histidine kinase
UCH003_RS00760	COG0745	RESPONSE REGULATOR receiver
UCH003_RS00780	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UCH003_RS00805	COG0028	Belongs to the TPP enzyme family
UCH003_RS00810	COG1309	transcriptional regulator
UCH003_RS00835	COG0577	efflux transmembrane transporter activity
UCH003_RS00875	COG1733	regulation of RNA biosynthetic process
UCH003_RS00880	COG2249	NAD(P)H dehydrogenase (quinone) activity
UCH003_RS00885	COG0778	Nitroreductase
UCH003_RS00900	COG2183	response to ionizing radiation
UCH003_RS00905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
UCH003_RS00920	COG1012	belongs to the aldehyde dehydrogenase family
UCH003_RS00925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
UCH003_RS00995	COG1674	ftsk spoiiie
UCH003_RS01035	COG2022	thiamine diphosphate biosynthetic process
UCH003_RS01040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
UCH003_RS01045	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
UCH003_RS01045	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
UCH003_RS01055	COG0242	peptide deformylase activity
UCH003_RS01065	COG0740	serine-type endopeptidase activity
UCH003_RS01070	COG0544	peptidyl-prolyl cis-trans isomerase activity
UCH003_RS01075	COG0302	gtp cyclohydrolase
UCH003_RS01080	COG1157	protein secretion by the type III secretion system
UCH003_RS01100	COG0314	molybdopterin synthase activity
UCH003_RS01105	COG0303	'Molybdopterin
UCH003_RS01115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
UCH003_RS01120	COG0840	transmembrane signaling receptor activity
UCH003_RS01120	COG3290	protein histidine kinase activity
UCH003_RS01140	COG4651	solute:proton antiporter activity
UCH003_RS01140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
UCH003_RS01155	COG1238	metal cluster binding
UCH003_RS01160	COG2814	Major facilitator Superfamily
UCH003_RS01170	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
UCH003_RS01185	COG0300	oxidoreductase activity
UCH003_RS01190	COG0840	transmembrane signaling receptor activity
UCH003_RS01190	COG3290	protein histidine kinase activity
UCH003_RS01205	COG3842	ATPase activity
UCH003_RS01210	COG1840	ABC-type Fe3 transport system, periplasmic component
UCH003_RS01220	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
UCH003_RS01225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
UCH003_RS01225	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
UCH003_RS01230	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
UCH003_RS01260	COG0745	RESPONSE REGULATOR receiver
UCH003_RS01265	COG0642	Histidine kinase
UCH003_RS01270	COG0745	RESPONSE REGULATOR receiver
UCH003_RS01280	COG1305	Transglutaminase-like
UCH003_RS01305	COG0513	Belongs to the DEAD box helicase family
UCH003_RS01310	COG3383	formate dehydrogenase (NAD+) activity
UCH003_RS01315	COG3150	esterase
UCH003_RS01345	COG1355	regulation of microtubule-based process
UCH003_RS01350	COG2207	Transcriptional regulator
UCH003_RS01350	COG3708	Transcriptional regulator
UCH003_RS01370	COG2985	domain, Protein
UCH003_RS01370	COG0490	domain, Protein
UCH003_RS01380	COG0840	transmembrane signaling receptor activity
UCH003_RS01440	COG0642	Histidine kinase
UCH003_RS01445	COG0745	RESPONSE REGULATOR receiver
UCH003_RS01490	COG3300	MHYT domain
UCH003_RS01490	COG5001	Diguanylate cyclase
UCH003_RS01500	COG1921	L-seryl-tRNASec selenium transferase activity
UCH003_RS01510	COG4191	Histidine kinase
UCH003_RS01535	COG0243	molybdopterin cofactor binding
UCH003_RS01540	COG3383	formate dehydrogenase (NAD+) activity
UCH003_RS01545	COG0437	4 iron, 4 sulfur cluster binding
UCH003_RS01560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
UCH003_RS01580	COG2890	protein-(glutamine-N5) methyltransferase activity
UCH003_RS01595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
UCH003_RS01610	COG0811	peptide transport
UCH003_RS01615	COG0848	biopolymer transport protein
UCH003_RS01625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
UCH003_RS01630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
UCH003_RS01640	COG2226	methyltransferase
UCH003_RS01650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UCH003_RS01655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UCH003_RS01660	COG1120	ATPase activity
UCH003_RS01665	COG4772	TonB-dependent receptor
UCH003_RS01670	COG0697	spore germination
UCH003_RS01675	COG2814	Major facilitator Superfamily
UCH003_RS01685	COG3447	MASE1 domain protein
UCH003_RS01685	COG5001	Diguanylate cyclase
UCH003_RS01685	COG5002	protein histidine kinase activity
UCH003_RS01690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UCH003_RS01700	COG0425	Belongs to the sulfur carrier protein TusA family
UCH003_RS01705	COG0709	Synthesizes selenophosphate from selenide and ATP
UCH003_RS01720	COG2011	ABC-type metal ion transport system permease component
UCH003_RS01725	COG3842	ATPase activity
UCH003_RS01735	COG3665	Urea carboxylase-associated protein
UCH003_RS01740	COG0439	Biotin carboxylase
UCH003_RS01790	COG0745	RESPONSE REGULATOR receiver
UCH003_RS01795	COG4191	Histidine kinase
UCH003_RS01800	COG0252	asparaginase activity
UCH003_RS01805	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
UCH003_RS01810	COG1027	Aspartate ammonia-lyase
UCH003_RS01815	COG1027	Aspartate ammonia-lyase
UCH003_RS01820	COG4774	siderophore transport
UCH003_RS01830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
UCH003_RS01835	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
UCH003_RS01860	COG0745	RESPONSE REGULATOR receiver
UCH003_RS01865	COG0642	Histidine kinase
UCH003_RS01890	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
UCH003_RS01895	COG1968	undecaprenyl-diphosphatase activity
UCH003_RS01900	COG1342	Belongs to the UPF0251 family
UCH003_RS01910	COG0840	transmembrane signaling receptor activity
UCH003_RS01915	COG2204	response regulator
UCH003_RS01920	COG4191	Histidine kinase
UCH003_RS01925	COG2199	diguanylate cyclase activity
UCH003_RS01925	COG2200	EAL domain
UCH003_RS01935	COG2194	sulfuric ester hydrolase activity
UCH003_RS01940	COG5002	protein histidine kinase activity
UCH003_RS01950	COG2962	Rard protein
UCH003_RS01955	COG2199	diguanylate cyclase activity
UCH003_RS01960	COG1393	Belongs to the ArsC family
UCH003_RS01965	COG1280	lysine exporter protein (LysE YggA)
UCH003_RS01995	COG1090	epimerase
UCH003_RS02000	COG1280	lysine exporter protein (LysE YggA)
UCH003_RS02010	COG0716	FMN binding
UCH003_RS02025	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
UCH003_RS02035	COG1742	UPF0060 membrane protein
UCH003_RS02050	COG0484	heat shock protein binding
UCH003_RS02055	COG0745	RESPONSE REGULATOR receiver
UCH003_RS02060	COG0835	chemotaxis
UCH003_RS02075	COG2198	Histidine kinase
UCH003_RS02075	COG0643	Histidine kinase
UCH003_RS02090	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
UCH003_RS02095	COG2201	protein-glutamate methylesterase activity
UCH003_RS02100	COG2205	protein histidine kinase activity
UCH003_RS02105	COG0745	RESPONSE REGULATOR receiver
UCH003_RS02120	COG2201	protein-glutamate methylesterase activity
UCH003_RS02130	COG0358	DNA primase activity
UCH003_RS02140	COG0328	RNA-DNA hybrid ribonuclease activity
UCH003_RS02145	COG0571	ribonuclease III activity
UCH003_RS02150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
UCH003_RS02160	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
UCH003_RS02170	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
UCH003_RS02185	COG0051	transcription antitermination factor activity, RNA binding
UCH003_RS02190	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
UCH003_RS02195	COG0088	Forms part of the polypeptide exit tunnel
UCH003_RS02200	COG0089	rRNA binding
UCH003_RS02205	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
UCH003_RS02210	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
UCH003_RS02220	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
UCH003_RS02225	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
UCH003_RS02230	COG0255	Belongs to the universal ribosomal protein uL29 family
UCH003_RS02235	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
UCH003_RS02240	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
UCH003_RS02245	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
UCH003_RS02255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
UCH003_RS02260	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
UCH003_RS02265	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
UCH003_RS02270	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
UCH003_RS02275	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
UCH003_RS02280	COG0200	Binds to the 23S rRNA
UCH003_RS02285	COG0201	protein transport
UCH003_RS02290	COG0024	Methionine aminopeptidase
UCH003_RS02300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
UCH003_RS02305	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
UCH003_RS02310	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
UCH003_RS02315	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
UCH003_RS02325	COG0203	ribosomal protein L17
UCH003_RS02340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
UCH003_RS02345	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
UCH003_RS02350	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
UCH003_RS02365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
UCH003_RS02370	COG0546	phosphoglycolate phosphatase activity
UCH003_RS02380	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
UCH003_RS02385	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
UCH003_RS02390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
UCH003_RS02410	COG0505	Belongs to the CarA family
UCH003_RS02425	COG0745	RESPONSE REGULATOR receiver
UCH003_RS02430	COG3278	Belongs to the heme-copper respiratory oxidase family
UCH003_RS02445	COG2010	Cytochrome c
UCH003_RS02470	COG1074	ATP-dependent DNA helicase activity
UCH003_RS02475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
UCH003_RS02480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UCH003_RS02490	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
UCH003_RS02495	COG0038	chloride channel
UCH003_RS02505	COG1979	alcohol dehydrogenase
UCH003_RS02510	COG2207	Transcriptional regulator
UCH003_RS02530	COG0519	Catalyzes the synthesis of GMP from XMP
UCH003_RS02545	COG0668	transmembrane transport
UCH003_RS02555	COG0546	phosphoglycolate phosphatase activity
UCH003_RS02560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
UCH003_RS02560	COG0674	pyruvate-flavodoxin oxidoreductase activity
UCH003_RS02560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
UCH003_RS02560	COG1013	pyruvate-flavodoxin oxidoreductase activity
UCH003_RS02595	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
UCH003_RS02600	COG3787	Belongs to the UPF0306 family
UCH003_RS02615	COG0477	Major facilitator Superfamily
UCH003_RS02620	COG2814	Major facilitator Superfamily
UCH003_RS02630	COG1702	phosphate starvation-inducible protein PhoH
UCH003_RS02655	COG0602	queuosine metabolic process
UCH003_RS02660	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
UCH003_RS02695	COG1607	acyl-coa hydrolase
UCH003_RS02705	COG0745	RESPONSE REGULATOR receiver
UCH003_RS02720	COG0514	ATP-dependent DNA helicase (RecQ)
UCH003_RS02730	COG3384	dioxygenase
UCH003_RS02735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
UCH003_RS02740	COG0581	inorganic phosphate transmembrane transporter activity
UCH003_RS02745	COG0573	inorganic phosphate transmembrane transporter activity
UCH003_RS02765	COG1671	Belongs to the UPF0178 family
UCH003_RS02775	COG2873	o-acetylhomoserine
UCH003_RS02785	COG0439	Biotin carboxylase
UCH003_RS02790	COG0390	transport system, permease component
UCH003_RS02805	COG4943	cyclic-guanylate-specific phosphodiesterase activity
UCH003_RS02810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
UCH003_RS02815	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
UCH003_RS02825	COG1091	dTDP-4-dehydrorhamnose reductase activity
UCH003_RS02835	COG1682	transport, permease protein
UCH003_RS02855	COG1442	glycosyl transferase family 8
UCH003_RS02865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
UCH003_RS02875	COG0028	Belongs to the TPP enzyme family
UCH003_RS02885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
UCH003_RS02890	COG1088	dTDP-glucose 4,6-dehydratase activity
UCH003_RS02895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UCH003_RS02910	COG0463	Glycosyl transferase, family 2
UCH003_RS02915	COG0463	Glycosyl transferase, family 2
UCH003_RS02925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
UCH003_RS02935	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
UCH003_RS02940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
UCH003_RS02945	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
UCH003_RS02955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UCH003_RS02960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UCH003_RS02965	COG0825	malonyl-CoA metabolic process
UCH003_RS02975	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
UCH003_RS02980	COG0723	plastoquinol--plastocyanin reductase activity
UCH003_RS02985	COG0445	tRNA wobble uridine modification
UCH003_RS02995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
UCH003_RS03000	COG1984	allophanate hydrolase subunit 2
UCH003_RS03005	COG3290	protein histidine kinase activity
UCH003_RS03005	COG0840	transmembrane signaling receptor activity
UCH003_RS03015	COG1496	oxidoreductase activity
UCH003_RS03025	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
UCH003_RS03035	COG5001	Diguanylate cyclase
UCH003_RS03035	COG5002	protein histidine kinase activity
UCH003_RS03040	COG2217	Heavy metal translocating P-type atpase
UCH003_RS03060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
UCH003_RS03070	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
UCH003_RS03070	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
UCH003_RS03075	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
UCH003_RS03110	COG0438	transferase activity, transferring glycosyl groups
UCH003_RS03120	COG1560	Kdo2-lipid A biosynthetic process
UCH003_RS03135	COG1793	dna ligase
UCH003_RS03140	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
UCH003_RS03150	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
UCH003_RS03155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UCH003_RS03185	COG0519	Catalyzes the synthesis of GMP from XMP
UCH003_RS03185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
UCH003_RS03200	COG0519	Catalyzes the synthesis of GMP from XMP
UCH003_RS03200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
UCH003_RS03220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
UCH003_RS03225	COG1287	oligosaccharyl transferase activity
UCH003_RS03235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
UCH003_RS03240	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
UCH003_RS03245	COG0745	RESPONSE REGULATOR receiver
UCH003_RS03250	COG2264	protein methyltransferase activity
UCH003_RS03255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
UCH003_RS03260	COG0688	phosphatidylethanolamine metabolic process
UCH003_RS03265	COG1183	phosphatidylcholine synthase activity
UCH003_RS03270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
UCH003_RS03280	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
UCH003_RS03290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
UCH003_RS03295	COG1160	GTP binding
UCH003_RS03300	COG0668	transmembrane transport
UCH003_RS03305	COG0697	spore germination
UCH003_RS03310	COG2877	3-deoxy-8-phosphooctulonate synthase activity
UCH003_RS03315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
UCH003_RS03320	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
UCH003_RS03325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
UCH003_RS03330	COG0284	orotidine-5'-phosphate decarboxylase activity
UCH003_RS03375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UCH003_RS03380	COG1136	(ABC) transporter
UCH003_RS03385	COG1136	(ABC) transporter
UCH003_RS03385	COG0577	efflux transmembrane transporter activity
UCH003_RS03410	COG5001	Diguanylate cyclase
UCH003_RS03415	COG1294	oxidase, subunit
UCH003_RS03420	COG1271	oxidase subunit
UCH003_RS03435	COG0668	transmembrane transport
UCH003_RS03450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
UCH003_RS03455	COG1686	Belongs to the peptidase S11 family
UCH003_RS03480	COG3842	ATPase activity
UCH003_RS03490	COG4149	molybdate abc transporter
UCH003_RS03500	COG1739	Uncharacterized protein family UPF0029
UCH003_RS03510	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
UCH003_RS03545	COG0582	viral genome integration into host DNA
UCH003_RS03550	COG2046	Belongs to the sulfate adenylyltransferase family
UCH003_RS03560	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
UCH003_RS03560	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
UCH003_RS03565	COG0489	protein tyrosine kinase activity
UCH003_RS03570	COG2171	N-acyltransferase activity
UCH003_RS03595	COG0784	Response regulator, receiver
UCH003_RS03610	COG0488	(ABC) transporter
UCH003_RS03630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
UCH003_RS03640	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
UCH003_RS03660	COG3706	GGDEF domain
UCH003_RS03665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
UCH003_RS03670	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
UCH003_RS03680	COG0133	tryptophan synthase activity
UCH003_RS03695	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
UCH003_RS03700	COG2252	PERMEase
UCH003_RS03720	COG3052	prosthetic group binding
UCH003_RS03725	COG2301	Belongs to the HpcH HpaI aldolase family
UCH003_RS03730	COG3051	citrate lyase alpha subunit
UCH003_RS03735	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
UCH003_RS03735	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
UCH003_RS03795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
UCH003_RS03890	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
UCH003_RS03905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
UCH003_RS03910	COG0772	Belongs to the SEDS family
UCH003_RS03915	COG1815	bacterial-type flagellum-dependent cell motility
UCH003_RS03920	COG1558	bacterial-type flagellum-dependent cell motility
UCH003_RS03925	COG1677	Flagellar hook-basal body complex protein FliE
UCH003_RS03935	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
UCH003_RS03955	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
UCH003_RS03965	COG0424	maF-like protein
UCH003_RS03970	COG0156	8-amino-7-oxononanoate synthase activity
UCH003_RS03975	COG0444	Belongs to the ABC transporter superfamily
UCH003_RS03985	COG0174	glutamine synthetase
UCH003_RS03990	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
UCH003_RS04000	COG0826	peptidase U32
UCH003_RS04005	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
UCH003_RS04015	COG0752	glycyl-tRNA synthetase alpha subunit
UCH003_RS04020	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
UCH003_RS04030	COG1519	Transferase
UCH003_RS04035	COG0564	pseudouridine synthase activity
UCH003_RS04040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
UCH003_RS04045	COG0228	four-way junction DNA binding
UCH003_RS04050	COG1837	Belongs to the UPF0109 family
UCH003_RS04055	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
UCH003_RS04060	COG0336	Belongs to the RNA methyltransferase TrmD family
UCH003_RS04065	COG0335	large ribosomal subunit rRNA binding
UCH003_RS04075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UCH003_RS04085	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
UCH003_RS04095	COG0540	Belongs to the ATCase OTCase family
UCH003_RS04100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
UCH003_RS04125	COG0210	DNA helicase
UCH003_RS04140	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
UCH003_RS04145	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
UCH003_RS04155	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
UCH003_RS04160	COG0542	response to heat
UCH003_RS04165	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
UCH003_RS04170	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
UCH003_RS04175	COG0815	Transfers the fatty acyl group on membrane lipoproteins
UCH003_RS04180	COG1862	Preprotein translocase
UCH003_RS04185	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
UCH003_RS04190	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
UCH003_RS04210	COG0285	dihydrofolate synthase activity
UCH003_RS04215	COG0739	heme binding
UCH003_RS04225	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
UCH003_RS04230	COG1692	metallophosphoesterase
UCH003_RS04245	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
UCH003_RS04255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
UCH003_RS04260	COG0135	phosphoribosylanthranilate isomerase activity
UCH003_RS04265	COG2176	DNA-directed DNA polymerase activity
UCH003_RS04270	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
UCH003_RS04275	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
UCH003_RS04285	COG0556	nucleotide-excision repair
UCH003_RS04305	COG2165	general secretion pathway protein
UCH003_RS04310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
UCH003_RS04315	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
UCH003_RS04320	COG0305	Participates in initiation and elongation during chromosome replication
UCH003_RS04320	COG0305	Participates in initiation and elongation during chromosome replication
UCH003_RS04335	COG0277	FAD linked oxidase domain protein
UCH003_RS04345	COG0739	heme binding
UCH003_RS04350	COG0598	Magnesium transport protein CorA
UCH003_RS04380	COG1918	ferrous iron import across plasma membrane
UCH003_RS04385	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
UCH003_RS04400	COG0642	Histidine kinase
UCH003_RS04405	COG0745	RESPONSE REGULATOR receiver
UCH003_RS04410	COG3162	membrane
UCH003_RS04415	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UCH003_RS04420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
UCH003_RS04440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UCH003_RS04445	COG4786	Flagellar basal body rod
UCH003_RS04455	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
UCH003_RS04465	COG2824	Alkylphosphonate utilization operon protein PhnA
UCH003_RS04495	COG0745	RESPONSE REGULATOR receiver
UCH003_RS04500	COG0642	Histidine kinase
UCH003_RS04505	COG5001	Diguanylate cyclase
UCH003_RS04505	COG3300	MHYT domain
UCH003_RS04515	COG0513	Belongs to the DEAD box helicase family
UCH003_RS04530	COG0514	ATP-dependent DNA helicase (RecQ)
UCH003_RS04535	COG4895	conserved protein (DUF2196)
UCH003_RS04560	COG0437	4 iron, 4 sulfur cluster binding
UCH003_RS04610	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
UCH003_RS04615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
UCH003_RS04635	COG0745	RESPONSE REGULATOR receiver
UCH003_RS04640	COG0642	Histidine kinase
UCH003_RS04645	COG2816	NAD+ diphosphatase activity
UCH003_RS04650	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
UCH003_RS04665	COG1119	ATPase activity
UCH003_RS04670	COG0066	3-isopropylmalate dehydratase activity
UCH003_RS04675	COG0473	3-isopropylmalate dehydrogenase activity
UCH003_RS04690	COG0617	tRNA 3'-terminal CCA addition
UCH003_RS04695	COG0788	formyltetrahydrofolate deformylase activity
UCH003_RS04700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
UCH003_RS04710	COG2081	HI0933 family
UCH003_RS04720	COG3123	guanosine phosphorylase activity
UCH003_RS04725	COG0288	reversible hydration of carbon dioxide
UCH003_RS04770	COG0347	Belongs to the P(II) protein family
UCH003_RS04775	COG0004	ammonium transporteR
UCH003_RS04785	COG0697	spore germination
UCH003_RS04790	COG1280	lysine exporter protein (LysE YggA)
UCH003_RS04795	COG0840	transmembrane signaling receptor activity
UCH003_RS04805	COG1410	methionine synthase
UCH003_RS04805	COG0646	methionine synthase
UCH003_RS04810	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
UCH003_RS04855	COG1230	cation diffusion facilitator family transporter
UCH003_RS04870	COG5002	protein histidine kinase activity
UCH003_RS04900	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
UCH003_RS04910	COG3608	succinylglutamate desuccinylase aspartoacylase
UCH003_RS04910	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
UCH003_RS04930	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UCH003_RS04935	COG0569	domain protein
UCH003_RS04940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
UCH003_RS04945	COG0745	RESPONSE REGULATOR receiver
UCH003_RS04950	COG2205	protein histidine kinase activity
UCH003_RS04955	COG4206	TonB-dependent receptor
UCH003_RS04965	COG1022	Amp-dependent synthetase and ligase
UCH003_RS04970	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
UCH003_RS04980	COG3437	response regulator, receiver
UCH003_RS05010	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
UCH003_RS05015	COG0805	protein transport
UCH003_RS05020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
UCH003_RS05030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
UCH003_RS05050	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
UCH003_RS05055	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
UCH003_RS05060	COG1607	acyl-coa hydrolase
UCH003_RS05075	COG0138	bifunctional purine biosynthesis protein purh
UCH003_RS05080	COG3158	transport of potassium into the cell
UCH003_RS05095	COG2151	metal-sulfur cluster biosynthetic enzyme
UCH003_RS05105	COG0840	transmembrane signaling receptor activity
UCH003_RS05110	COG0488	(ABC) transporter
UCH003_RS05115	COG3290	protein histidine kinase activity
UCH003_RS05115	COG0840	transmembrane signaling receptor activity
UCH003_RS05120	COG0501	Belongs to the peptidase M48B family
UCH003_RS05135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
UCH003_RS05140	COG0849	cell division
UCH003_RS05145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UCH003_RS05150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
UCH003_RS05155	COG0275	rRNA processing
UCH003_RS05170	COG2217	Heavy metal translocating P-type atpase
UCH003_RS05185	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
UCH003_RS05205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
UCH003_RS05240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
UCH003_RS05245	COG1331	Highly conserved protein containing a thioredoxin domain
UCH003_RS05255	COG0326	Molecular chaperone. Has ATPase activity
UCH003_RS05260	COG0204	Acyl-transferase
UCH003_RS05270	COG0047	phosphoribosylformylglycinamidine synthase activity
UCH003_RS05275	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
UCH003_RS05280	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
UCH003_RS05285	COG0793	Belongs to the peptidase S41A family
UCH003_RS05290	COG0542	response to heat
UCH003_RS05305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
UCH003_RS05320	COG4865	methylaspartate mutase activity
UCH003_RS05335	COG0230	Belongs to the bacterial ribosomal protein bL34 family
UCH003_RS05345	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
UCH003_RS05350	COG0706	membrane insertase activity
UCH003_RS05360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
UCH003_RS05365	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
UCH003_RS05395	COG0642	Histidine kinase
UCH003_RS05400	COG0745	RESPONSE REGULATOR receiver
UCH003_RS05405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UCH003_RS05410	COG0484	heat shock protein binding
UCH003_RS05415	COG0789	Transcriptional regulator
UCH003_RS05425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UCH003_RS05430	COG0494	nUDIX hydrolase
UCH003_RS05435	COG0527	aspartate kinase activity
UCH003_RS05450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
UCH003_RS05460	COG0730	response to heat
UCH003_RS05465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
UCH003_RS05470	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
UCH003_RS05475	COG0196	riboflavin kinase activity
UCH003_RS05480	COG2226	methyltransferase
UCH003_RS05490	COG2404	hydrolase activity, acting on ester bonds
UCH003_RS05495	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
UCH003_RS05500	COG1959	2 iron, 2 sulfur cluster binding
UCH003_RS05505	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
UCH003_RS05525	COG1420	regulation of RNA biosynthetic process
UCH003_RS05530	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
UCH003_RS05535	COG0443	Heat shock 70 kDa protein
UCH003_RS05540	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
UCH003_RS05550	COG4232	protein-disulfide reductase activity
UCH003_RS05560	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
UCH003_RS05565	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
UCH003_RS05570	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
UCH003_RS05575	COG1663	tetraacyldisaccharide 4'-kinase activity
UCH003_RS05580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UCH003_RS05585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
UCH003_RS05595	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
UCH003_RS05595	COG2050	protein possibly involved in aromatic compounds catabolism
UCH003_RS05600	COG0500	methyltransferase
UCH003_RS05610	COG2195	Cleaves the N-terminal amino acid of tripeptides
UCH003_RS05620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
UCH003_RS05625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UCH003_RS05640	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
UCH003_RS05650	COG0521	Mo-molybdopterin cofactor biosynthetic process
UCH003_RS05655	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
UCH003_RS05660	COG0525	valine-tRNA ligase activity
UCH003_RS05665	COG3706	GGDEF domain
UCH003_RS05675	COG1959	2 iron, 2 sulfur cluster binding
UCH003_RS05695	COG0142	geranyltranstransferase activity
UCH003_RS05700	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
UCH003_RS05705	COG0442	prolyl-tRNA aminoacylation
UCH003_RS05715	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
UCH003_RS05715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
UCH003_RS05725	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
UCH003_RS05740	COG1592	Rubrerythrin
UCH003_RS05745	COG0582	viral genome integration into host DNA
UCH003_RS05750	COG1610	YqeY-like protein
UCH003_RS05755	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
UCH003_RS05760	COG0280	phosphate acetyltransferase
UCH003_RS05760	COG0857	belongs to the CobB CobQ family
UCH003_RS05765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
UCH003_RS05770	COG1254	Belongs to the acylphosphatase family
UCH003_RS05785	COG1181	Belongs to the D-alanine--D-alanine ligase family
UCH003_RS05790	COG0632	four-way junction helicase activity
UCH003_RS05800	COG0728	peptidoglycan biosynthetic process
UCH003_RS05805	COG0215	cysteine-tRNA ligase activity
UCH003_RS05810	COG1132	(ABC) transporter
UCH003_RS05815	COG0167	dihydroorotate dehydrogenase activity
UCH003_RS05825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UCH003_RS05830	COG1028	Short-chain dehydrogenase reductase Sdr
UCH003_RS05835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
UCH003_RS05840	COG0750	zinc metalloprotease
UCH003_RS05845	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
UCH003_RS05865	COG3437	response regulator, receiver
UCH003_RS05865	COG0784	Response regulator, receiver
UCH003_RS05875	COG0437	4 iron, 4 sulfur cluster binding
UCH003_RS05880	COG3383	formate dehydrogenase (NAD+) activity
UCH003_RS05885	COG0243	molybdopterin cofactor binding
UCH003_RS05900	COG2095	MarC family integral membrane protein
UCH003_RS05905	COG0842	Transport permease protein
UCH003_RS05915	COG0842	Transport permease protein
UCH003_RS05915	COG1129	ABC transporter
UCH003_RS05965	COG3962	Belongs to the TPP enzyme family
UCH003_RS05970	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
UCH003_RS05970	COG0674	pyruvate-flavodoxin oxidoreductase activity
UCH003_RS05980	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
UCH003_RS05985	COG0045	succinate-CoA ligase (ADP-forming) activity
UCH003_RS05990	COG0039	L-malate dehydrogenase activity
UCH003_RS06020	COG0375	protein maturation
UCH003_RS06025	COG0309	Hydrogenase expression formation protein (HypE)
UCH003_RS06035	COG0298	carbon dioxide binding
UCH003_RS06065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
UCH003_RS06070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
UCH003_RS06080	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
UCH003_RS06090	COG0343	queuine tRNA-ribosyltransferase activity
UCH003_RS06115	COG0745	RESPONSE REGULATOR receiver
UCH003_RS06135	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
UCH003_RS06135	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
UCH003_RS06145	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
UCH003_RS06170	COG0163	prenyltransferase activity
UCH003_RS06175	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
UCH003_RS06180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
UCH003_RS06185	COG0124	histidyl-tRNA synthetase
UCH003_RS06190	COG1166	arginine decarboxylase activity
UCH003_RS06195	COG1045	serine acetyltransferase
UCH003_RS06225	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
UCH003_RS06235	COG0493	'glutamate synthase
UCH003_RS06245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UCH003_RS06250	COG0440	acetolactate synthase activity
UCH003_RS06255	COG0028	Belongs to the TPP enzyme family
UCH003_RS06265	COG0446	pyridine nucleotide-disulphide oxidoreductase
UCH003_RS06280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
UCH003_RS06285	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
UCH003_RS06310	COG0310	cobalt ion transport
UCH003_RS06320	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
UCH003_RS06330	COG0134	indole-3-glycerol-phosphate synthase activity
UCH003_RS06340	COG0727	PFAM Uncharacterised protein family (UPF0153)
UCH003_RS06360	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
UCH003_RS06370	COG0586	Pfam SNARE associated Golgi protein
UCH003_RS06385	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
UCH003_RS06390	COG0840	transmembrane signaling receptor activity
UCH003_RS06390	COG5278	phosphoserine phosphatase activity
UCH003_RS06395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UCH003_RS06400	COG4597	amino acid ABC transporter
UCH003_RS06405	COG0765	amino acid transport
UCH003_RS06410	COG1126	abc transporter atp-binding protein
UCH003_RS06420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
UCH003_RS06425	COG1832	CoA-binding protein
UCH003_RS06435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
UCH003_RS06480	COG0745	RESPONSE REGULATOR receiver
UCH003_RS06485	COG2198	Histidine kinase
UCH003_RS06485	COG0784	Response regulator, receiver
UCH003_RS06485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UCH003_RS06485	COG2205	protein histidine kinase activity
UCH003_RS06510	COG0745	RESPONSE REGULATOR receiver
UCH003_RS06520	COG1049	propionate catabolic process, 2-methylcitrate cycle
UCH003_RS06525	COG1196	nuclear chromosome segregation
UCH003_RS06525	COG1674	ftsk spoiiie
UCH003_RS06530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
UCH003_RS06535	COG0776	regulation of translation
UCH003_RS06540	COG0306	phosphate transporter
UCH003_RS06565	COG2814	Major facilitator Superfamily
UCH003_RS06575	COG0640	Transcriptional regulator
UCH003_RS06585	COG2267	carboxylic ester hydrolase activity
UCH003_RS06595	COG4589	Belongs to the CDS family
UCH003_RS06600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
UCH003_RS06785	COG2369	cell adhesion
UCH003_RS06825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
UCH003_RS06830	COG1137	ATPase activity
UCH003_RS06845	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
UCH003_RS06850	COG0137	argininosuccinate synthase activity
UCH003_RS06855	COG1054	Belongs to the UPF0176 family
UCH003_RS06860	COG0359	binds to the 23S rRNA
UCH003_RS06865	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
UCH003_RS06870	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
UCH003_RS06910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UCH003_RS06940	COG2040	homocysteine
UCH003_RS06965	COG1309	transcriptional regulator
UCH003_RS06970	COG0242	peptide deformylase activity
UCH003_RS06985	COG2207	Transcriptional regulator
UCH003_RS07000	COG2026	Addiction module toxin, RelE StbE family
UCH003_RS07005	COG1187	pseudouridine synthase activity
UCH003_RS07015	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
UCH003_RS07020	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
UCH003_RS07025	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
UCH003_RS07030	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
UCH003_RS07035	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
UCH003_RS07040	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
UCH003_RS07065	COG0166	Belongs to the GPI family
UCH003_RS07070	COG1032	radical SAM domain protein
UCH003_RS07105	COG1338	Plays a role in the flagellum-specific transport system
UCH003_RS07110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
UCH003_RS07125	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
UCH003_RS07135	COG0101	tRNA pseudouridine synthase activity
UCH003_RS07140	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
UCH003_RS07145	COG1472	Belongs to the glycosyl hydrolase 3 family
UCH003_RS07150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
UCH003_RS07160	COG0352	thiamine-phosphate diphosphorylase activity
UCH003_RS07170	COG0356	it plays a direct role in the translocation of protons across the membrane
UCH003_RS07175	COG1942	4-Oxalocrotonate Tautomerase
UCH003_RS07180	COG0659	secondary active sulfate transmembrane transporter activity
UCH003_RS07190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UCH003_RS07210	COG3951	Flagellar rod assembly protein muramidase FlgJ
UCH003_RS07215	COG1706	bacterial-type flagellum-dependent cell motility
UCH003_RS07220	COG0742	ribosomal rna small subunit methyltransferase
UCH003_RS07250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UCH003_RS07265	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
UCH003_RS07285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
UCH003_RS07295	COG0840	transmembrane signaling receptor activity
UCH003_RS07295	COG3290	protein histidine kinase activity
UCH003_RS07300	COG0415	Belongs to the DNA photolyase family
UCH003_RS07305	COG0778	Nitroreductase
UCH003_RS07340	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
UCH003_RS07345	COG1360	Flagellar Motor Protein
UCH003_RS07350	COG0488	(ABC) transporter
UCH003_RS07360	COG1234	tRNA 3'-trailer cleavage
UCH003_RS07375	COG0784	Response regulator, receiver
UCH003_RS07375	COG3437	response regulator, receiver
UCH003_RS07390	COG0428	transporter
UCH003_RS07395	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
UCH003_RS07405	COG0351	phosphomethylpyrimidine kinase
UCH003_RS07405	COG0352	thiamine-phosphate diphosphorylase activity
UCH003_RS07425	COG0475	glutathione-regulated potassium exporter activity
UCH003_RS07425	COG0569	domain protein
UCH003_RS07435	COG0840	transmembrane signaling receptor activity
UCH003_RS07440	COG0585	pseudouridine synthase activity
UCH003_RS07445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
UCH003_RS07480	COG1053	succinate dehydrogenase
UCH003_RS07490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
UCH003_RS07495	COG1047	Peptidyl-prolyl cis-trans
UCH003_RS07500	COG1139	Iron-sulfur cluster binding protein
UCH003_RS07540	COG3260	NADH ubiquinone oxidoreductase 20
UCH003_RS07560	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
UCH003_RS07570	COG0493	'glutamate synthase
UCH003_RS07570	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
UCH003_RS07575	COG0583	DNA-binding transcription factor activity
UCH003_RS07580	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
UCH003_RS07585	COG0066	3-isopropylmalate dehydratase activity
UCH003_RS07595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UCH003_RS07595	COG3153	acetyltransferase
UCH003_RS07605	COG0745	RESPONSE REGULATOR receiver
UCH003_RS07610	COG0642	Histidine kinase
UCH003_RS07620	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
UCH003_RS07635	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
UCH003_RS07650	COG0745	RESPONSE REGULATOR receiver
UCH003_RS07655	COG0747	negative chemotaxis
UCH003_RS07670	COG0243	molybdopterin cofactor binding
UCH003_RS07675	COG0840	transmembrane signaling receptor activity
UCH003_RS07705	COG1113	amino acid transport
UCH003_RS07720	COG3041	Addiction module toxin RelE StbE family
UCH003_RS07730	COG1451	nucleotide metabolic process
UCH003_RS07790	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
UCH003_RS07815	COG0716	FMN binding
UCH003_RS07825	COG1433	Dinitrogenase iron-molybdenum cofactor
UCH003_RS07845	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
UCH003_RS07850	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
UCH003_RS07865	COG0426	domain, Protein
UCH003_RS07870	COG3287	FIST C domain
UCH003_RS07870	COG2199	diguanylate cyclase activity
UCH003_RS07870	COG2200	EAL domain
UCH003_RS07875	COG0745	RESPONSE REGULATOR receiver
UCH003_RS07885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
UCH003_RS07900	COG1573	uracil-dna glycosylase
UCH003_RS07910	COG0824	Thioesterase
UCH003_RS07915	COG4263	nitrous-oxide reductase activity
UCH003_RS07935	COG1177	transmembrane transport
UCH003_RS07940	COG3842	ATPase activity
UCH003_RS07945	COG0725	ABC transporter, periplasmic molybdate-binding protein
UCH003_RS07955	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
UCH003_RS07965	COG0437	4 iron, 4 sulfur cluster binding
UCH003_RS07990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
UCH003_RS08025	COG1136	(ABC) transporter
UCH003_RS08050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UCH003_RS08055	COG1981	membrane
UCH003_RS08060	COG1333	cytochrome c biogenesis protein
UCH003_RS08060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UCH003_RS08065	COG3301	Polysulphide reductase, NrfD
UCH003_RS08070	COG0437	4 iron, 4 sulfur cluster binding
UCH003_RS08075	COG0545	Peptidyl-prolyl cis-trans isomerase
UCH003_RS08080	COG0484	heat shock protein binding
UCH003_RS08090	COG0745	RESPONSE REGULATOR receiver
UCH003_RS08095	COG0546	phosphoglycolate phosphatase activity
UCH003_RS08100	COG0500	methyltransferase
UCH003_RS08105	COG1309	transcriptional regulator
UCH003_RS08130	COG0500	methyltransferase
UCH003_RS08160	COG0577	efflux transmembrane transporter activity
UCH003_RS08165	COG1136	(ABC) transporter
UCH003_RS08180	COG2353	YceI-like domain
UCH003_RS08185	COG1408	metallophosphoesterase
UCH003_RS08200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
UCH003_RS08315	COG2369	cell adhesion
UCH003_RS08480	COG1518	maintenance of DNA repeat elements
UCH003_RS08520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
UCH003_RS08555	COG2199	diguanylate cyclase activity
UCH003_RS08555	COG3287	FIST C domain
UCH003_RS08555	COG2200	EAL domain
UCH003_RS08565	COG4753	response regulator
UCH003_RS08565	COG2207	Transcriptional regulator
UCH003_RS08575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
UCH003_RS08590	COG0586	Pfam SNARE associated Golgi protein
UCH003_RS08600	COG1132	(ABC) transporter
UCH003_RS08605	COG1418	mRNA catabolic process
UCH003_RS08620	COG0552	protein localization to endoplasmic reticulum
UCH003_RS08625	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
UCH003_RS08630	COG1580	Controls the rotational direction of flagella during chemotaxis
UCH003_RS08635	COG0736	holo-[acyl-carrier-protein] synthase activity
UCH003_RS08650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
UCH003_RS08655	COG2860	membrane
UCH003_RS08660	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
UCH003_RS08670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
UCH003_RS08675	COG0730	response to heat
UCH003_RS08690	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
UCH003_RS08695	COG2894	cell division
UCH003_RS08700	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
UCH003_RS08710	COG0557	exoribonuclease II activity
UCH003_RS08715	COG1466	dna polymerase III delta subunit
UCH003_RS08720	COG0360	Binds together with S18 to 16S ribosomal RNA
UCH003_RS08725	COG0629	single-stranded DNA binding
UCH003_RS08730	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
UCH003_RS08735	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
UCH003_RS08740	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UCH003_RS08745	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
UCH003_RS08770	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
UCH003_RS08775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
UCH003_RS08780	COG0612	Peptidase, M16
UCH003_RS08785	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
UCH003_RS08800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
UCH003_RS08810	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
UCH003_RS08815	COG0681	Belongs to the peptidase S26 family
UCH003_RS08820	COG1994	Peptidase M50
UCH003_RS08825	COG0698	ribose 5-phosphate isomerase
UCH003_RS08840	COG0133	tryptophan synthase activity
UCH003_RS08850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
UCH003_RS08855	COG2201	protein-glutamate methylesterase activity
UCH003_RS08860	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
UCH003_RS08880	COG0501	Belongs to the peptidase M48B family
UCH003_RS08885	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
UCH003_RS08920	COG0523	cobalamin synthesis protein
UCH003_RS08925	COG2879	small protein
UCH003_RS08930	COG1966	Carbon starvation protein
UCH003_RS08950	COG0697	spore germination
UCH003_RS08955	COG1556	Lactate utilization protein
UCH003_RS08960	COG1139	Iron-sulfur cluster binding protein
UCH003_RS08965	COG0247	lactate metabolic process
UCH003_RS08980	COG1272	protein, Hemolysin III
UCH003_RS08990	COG0352	thiamine-phosphate diphosphorylase activity
UCH003_RS09000	COG2169	Transcriptional regulator
UCH003_RS09000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
UCH003_RS09005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
UCH003_RS09010	COG0840	transmembrane signaling receptor activity
UCH003_RS09020	COG2217	Heavy metal translocating P-type atpase
UCH003_RS09030	COG3610	response to peptide
UCH003_RS09035	COG2966	Psort location CytoplasmicMembrane, score
UCH003_RS09045	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
UCH003_RS09050	COG2308	Evidence 4 Homologs of previously reported genes of
UCH003_RS09095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UCH003_RS09160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UCH003_RS09205	COG1136	(ABC) transporter
UCH003_RS09230	COG0348	domain, Protein
UCH003_RS09245	COG0437	4 iron, 4 sulfur cluster binding
UCH003_RS09260	COG4263	nitrous-oxide reductase activity
UCH003_RS09265	COG3852	Histidine kinase
UCH003_RS09270	COG0745	RESPONSE REGULATOR receiver
UCH003_RS09275	COG2863	cytochrome
UCH003_RS09280	COG0723	plastoquinol--plastocyanin reductase activity
UCH003_RS09285	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
UCH003_RS09310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
UCH003_RS09385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
UCH003_RS09400	COG2358	TRAP transporter, solute receptor (TAXI family
UCH003_RS09410	COG0217	transcriptional regulatory protein
UCH003_RS09430	COG0784	Response regulator, receiver
UCH003_RS09430	COG3437	response regulator, receiver
UCH003_RS09440	COG2258	MOSC domain
UCH003_RS09445	COG2226	methyltransferase
UCH003_RS09450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
UCH003_RS09455	COG1160	GTP binding
UCH003_RS09460	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
UCH003_RS09465	COG1027	Aspartate ammonia-lyase
UCH003_RS09485	COG4624	Iron only hydrogenase large subunit, C-terminal domain
UCH003_RS09485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
UCH003_RS09495	COG2964	Protein conserved in bacteria
UCH003_RS09520	COG4452	Inner membrane protein CreD
UCH003_RS09525	COG0513	Belongs to the DEAD box helicase family
UCH003_RS09535	COG0688	phosphatidylethanolamine metabolic process
UCH003_RS09540	COG3287	FIST C domain
UCH003_RS09540	COG2200	EAL domain
UCH003_RS09540	COG2199	diguanylate cyclase activity
UCH003_RS09555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
UCH003_RS09560	COG0723	plastoquinol--plastocyanin reductase activity
UCH003_RS09565	COG2863	cytochrome
UCH003_RS09580	COG0745	RESPONSE REGULATOR receiver
UCH003_RS09595	COG0243	molybdopterin cofactor binding
UCH003_RS09605	COG0012	GTP binding
UCH003_RS09625	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
UCH003_RS09625	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
UCH003_RS09630	COG3043	anaerobic respiration
UCH003_RS09635	COG0348	domain, Protein
UCH003_RS09640	COG0437	4 iron, 4 sulfur cluster binding
UCH003_RS09645	COG0243	molybdopterin cofactor binding
UCH003_RS09650	COG1051	belongs to the nudix hydrolase family
UCH003_RS09680	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
UCH003_RS09690	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
UCH003_RS09695	COG0651	ATP synthesis coupled electron transport
UCH003_RS09700	COG0650	Formate hydrogenlyase subunit 4
UCH003_RS09705	COG4237	Hydrogenase 4 membrane
UCH003_RS09710	COG0651	ATP synthesis coupled electron transport
UCH003_RS09715	COG3261	NADH dehydrogenase
UCH003_RS09715	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
UCH003_RS09725	COG3260	NADH ubiquinone oxidoreductase 20
UCH003_RS09740	COG1116	anion transmembrane transporter activity
UCH003_RS09745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
UCH003_RS09755	COG2226	methyltransferase
UCH003_RS09760	COG0398	Pfam SNARE associated Golgi protein
UCH003_RS09770	COG0398	Pfam SNARE associated Golgi protein
UCH003_RS09785	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
UCH003_RS09800	COG1346	cytolysis
UCH003_RS09820	COG1333	cytochrome c biogenesis protein
UCH003_RS09820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UCH003_RS09830	COG3005	denitrification pathway
UCH003_RS09865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
UCH003_RS09870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
UCH003_RS09895	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
UCH003_RS09905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UCH003_RS09905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UCH003_RS09925	COG0768	penicillin binding
UCH003_RS09940	COG0218	Necessary for normal cell division and for the maintenance of normal septation
UCH003_RS09955	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
UCH003_RS09960	COG0131	Imidazoleglycerol-phosphate dehydratase
UCH003_RS09965	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
UCH003_RS09975	COG0084	hydrolase, TatD family'
UCH003_RS09980	COG3706	GGDEF domain
UCH003_RS09985	COG1620	l-lactate permease
UCH003_RS09990	COG0497	DNA recombination
UCH003_RS09995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
UCH003_RS10005	COG3706	GGDEF domain
UCH003_RS10010	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
UCH003_RS10015	COG0563	adenylate kinase activity
UCH003_RS10025	COG0860	N-Acetylmuramoyl-L-alanine amidase
UCH003_RS10035	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
UCH003_RS10050	COG0528	UMP kinase activity
UCH003_RS10065	COG1136	(ABC) transporter
UCH003_RS10070	COG0220	tRNA (guanine-N7-)-methyltransferase activity
UCH003_RS10075	COG0366	Alpha amylase catalytic
UCH003_RS10075	COG3103	Sh3 type 3 domain protein
UCH003_RS10080	COG0564	pseudouridine synthase activity
UCH003_RS10085	COG0772	Belongs to the SEDS family
UCH003_RS10100	COG0569	domain protein
UCH003_RS10110	COG1380	Effector of murein hydrolase LrgA
UCH003_RS10115	COG1346	cytolysis
UCH003_RS10125	COG0642	Histidine kinase
UCH003_RS10130	COG0587	DNA-directed DNA polymerase activity
UCH003_RS10140	COG0840	transmembrane signaling receptor activity
UCH003_RS10140	COG0840	transmembrane signaling receptor activity
UCH003_RS10145	COG0840	transmembrane signaling receptor activity
UCH003_RS10160	COG1902	pentaerythritol trinitrate reductase activity
UCH003_RS10170	COG2200	EAL domain
UCH003_RS10170	COG3287	FIST C domain
UCH003_RS10170	COG2199	diguanylate cyclase activity
UCH003_RS10175	COG0765	amino acid transport
UCH003_RS10195	COG1981	membrane
UCH003_RS10215	COG2081	HI0933 family
UCH003_RS10220	COG2996	Protein conserved in bacteria
UCH003_RS10230	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
UCH003_RS10240	COG0693	protein deglycase activity
UCH003_RS10245	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
UCH003_RS10255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UCH003_RS10265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UCH003_RS10280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
UCH003_RS10290	COG1185	polyribonucleotide nucleotidyltransferase activity
UCH003_RS10290	COG0539	negative regulation of cytoplasmic translation
UCH003_RS10295	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
UCH003_RS10300	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
UCH003_RS10305	COG0072	phenylalanine-tRNA ligase activity
UCH003_RS10305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UCH003_RS10310	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
UCH003_RS10315	COG0537	adenosine 5'-monophosphoramidase activity
UCH003_RS10320	COG0165	Argininosuccinate lyase
UCH003_RS10325	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
UCH003_RS10330	COG4770	biotin carboxylase activity
UCH003_RS10350	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
UCH003_RS10355	COG0745	RESPONSE REGULATOR receiver
UCH003_RS10360	COG2205	protein histidine kinase activity
UCH003_RS10360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UCH003_RS10375	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
UCH003_RS10405	COG0519	Catalyzes the synthesis of GMP from XMP
UCH003_RS10405	COG0518	GMP synthase (glutamine-hydrolyzing) activity
UCH003_RS10415	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
UCH003_RS10425	COG0322	excinuclease ABC activity
UCH003_RS10440	COG0784	Response regulator, receiver
UCH003_RS10440	COG5002	protein histidine kinase activity
UCH003_RS10440	COG2205	protein histidine kinase activity
UCH003_RS10450	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
UCH003_RS10455	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
UCH003_RS10475	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
UCH003_RS10500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
UCH003_RS10505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
UCH003_RS10520	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
UCH003_RS10525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
UCH003_RS10530	COG0318	PFAM AMP-dependent synthetase and ligase
UCH003_RS10535	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
UCH003_RS10540	COG0642	Histidine kinase
UCH003_RS10545	COG0745	RESPONSE REGULATOR receiver
UCH003_RS10555	COG0484	heat shock protein binding
UCH003_RS10570	COG1971	Probably functions as a manganese efflux pump
UCH003_RS10575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
UCH003_RS10575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
UCH003_RS10585	COG1301	dicarboxylic acid transport
UCH003_RS10590	COG1301	dicarboxylic acid transport
UCH003_RS10595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
UCH003_RS10605	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
UCH003_RS10610	COG0748	coenzyme F420 binding
UCH003_RS10630	COG0708	Exodeoxyribonuclease III
UCH003_RS10655	COG5001	Diguanylate cyclase
UCH003_RS10655	COG3300	MHYT domain
UCH003_RS10660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
UCH003_RS10670	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
UCH003_RS10675	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
UCH003_RS10680	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
UCH003_RS10690	COG0493	'glutamate synthase
UCH003_RS10695	COG0067	glutamate synthase
UCH003_RS10695	COG0069	glutamate synthase activity
UCH003_RS10695	COG0070	glutamate synthase
UCH003_RS10705	COG0037	tRNA processing
UCH003_RS10710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
UCH003_RS10715	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
UCH003_RS10725	COG1047	Peptidyl-prolyl cis-trans
UCH003_RS10740	COG0823	Involved in the tonB-independent uptake of proteins
UCH003_RS10750	COG0848	biopolymer transport protein
UCH003_RS10755	COG0811	peptide transport
UCH003_RS10765	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
UCH003_RS10770	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
UCH003_RS10785	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
UCH003_RS10790	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
UCH003_RS10795	COG1475	DNA binding
UCH003_RS10800	COG1192	Involved in chromosome partitioning
UCH003_RS10815	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
UCH003_RS10820	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
UCH003_RS10825	COG0211	Belongs to the bacterial ribosomal protein bL27 family
UCH003_RS10830	COG0261	This protein binds to 23S rRNA in the presence of protein L20
UCH003_RS10835	COG0469	pyruvate kinase activity
UCH003_RS10870	COG0579	oxidoreductase
UCH003_RS10875	COG0251	oxidation-reduction process
UCH003_RS10880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
UCH003_RS10885	COG1193	negative regulation of DNA recombination
UCH003_RS10900	COG0436	Aminotransferase
UCH003_RS10910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
UCH003_RS10925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
UCH003_RS10930	COG0517	IMP dehydrogenase activity
UCH003_RS10930	COG0516	GMP reductase activity
UCH003_RS10940	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
UCH003_RS10945	COG1058	Belongs to the CinA family
UCH003_RS10945	COG1546	Belongs to the CinA family
UCH003_RS10985	COG1333	cytochrome c biogenesis protein
UCH003_RS10985	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UCH003_RS11030	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
UCH003_RS11040	COG2207	Transcriptional regulator
UCH003_RS11040	COG4753	response regulator
UCH003_RS11075	COG1944	ATP diphosphatase activity
UCH003_RS11080	COG0513	Belongs to the DEAD box helicase family
UCH003_RS11095	COG2329	Antibiotic biosynthesis monooxygenase
UCH003_RS11130	COG1151	hydroxylamine reductase activity
UCH003_RS11135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
UCH003_RS11140	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
UCH003_RS11170	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
UCH003_RS11175	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
UCH003_RS11180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
UCH003_RS11220	COG0195	Participates in both transcription termination and antitermination
UCH003_RS11225	COG0601	transmembrane transport
UCH003_RS11230	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
UCH003_RS11235	COG0149	triose-phosphate isomerase activity
UCH003_RS11245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
UCH003_RS11250	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
UCH003_RS11285	COG0018	arginyl-trna synthetase
UCH003_RS11290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
UCH003_RS11295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
UCH003_RS11300	COG0194	GDP metabolic process
UCH003_RS11310	COG1684	flagellar biosynthetic protein fliR
UCH003_RS11340	COG0159	tryptophan synthase activity
UCH003_RS11350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
UCH003_RS11355	COG2255	four-way junction helicase activity
UCH003_RS11360	COG0628	permease
UCH003_RS11365	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
UCH003_RS11375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
UCH003_RS11380	COG1053	succinate dehydrogenase
UCH003_RS11390	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
UCH003_RS11395	COG3706	GGDEF domain
UCH003_RS11410	COG3437	response regulator, receiver
UCH003_RS11415	COG3012	SEC-C Motif Domain Protein
UCH003_RS11425	COG3706	GGDEF domain
UCH003_RS11430	COG1280	lysine exporter protein (LysE YggA)
UCH003_RS11470	COG0247	lactate metabolic process
UCH003_RS11475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UCH003_RS11485	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
UCH003_RS11490	COG0113	porphobilinogen synthase activity
UCH003_RS11495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
UCH003_RS11505	COG1970	mechanosensitive ion channel activity
UCH003_RS11510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
UCH003_RS11520	COG0840	transmembrane signaling receptor activity
UCH003_RS11525	COG0357	Ribosomal RNA small subunit methyltransferase G
UCH003_RS11545	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
UCH003_RS11560	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UCH003_RS11565	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UCH003_RS11570	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UCH003_RS11570	COG0649	NAD binding
UCH003_RS11575	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
UCH003_RS11595	COG1007	ATP synthesis coupled electron transport
UCH003_RS11605	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
UCH003_RS11610	COG0713	ATP synthesis coupled electron transport
UCH003_RS11615	COG0839	Belongs to the complex I subunit 6 family
UCH003_RS11620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UCH003_RS11625	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
UCH003_RS11630	COG1034	ATP synthesis coupled electron transport
UCH003_RS11640	COG0840	transmembrane signaling receptor activity
UCH003_RS11645	COG0840	transmembrane signaling receptor activity
UCH003_RS11660	COG0745	RESPONSE REGULATOR receiver
UCH003_RS11685	COG0697	spore germination
UCH003_RS11695	COG1464	Belongs to the NlpA lipoprotein family
UCH003_RS11700	COG2011	ABC-type metal ion transport system permease component
UCH003_RS11705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
UCH003_RS11710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
UCH003_RS11720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
UCH003_RS11725	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
UCH003_RS11730	COG0085	RNA polymerase activity
UCH003_RS11735	COG0222	ribosome binding
UCH003_RS11740	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
UCH003_RS11745	COG0081	regulation of translation
UCH003_RS11750	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
UCH003_RS11755	COG0250	Participates in transcription elongation, termination and antitermination
UCH003_RS11765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
UCH003_RS11770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
UCH003_RS11795	COG3022	response to hydroperoxide
UCH003_RS11810	COG0506	proline dehydrogenase activity
UCH003_RS11810	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
UCH003_RS11810	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
UCH003_RS11835	COG0683	leucine binding
UCH003_RS11850	COG4221	oxidoreductase activity
UCH003_RS11855	COG4628	conserved protein (DUF2132)
UCH003_RS11880	COG4336	lyase activity
UCH003_RS11890	COG3118	belongs to the thioredoxin family
UCH003_RS11910	COG2199	diguanylate cyclase activity
UCH003_RS11910	COG3287	FIST C domain
UCH003_RS11910	COG2200	EAL domain
UCH003_RS11930	COG2010	Cytochrome c
UCH003_RS11935	COG0693	protein deglycase activity
UCH003_RS11960	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
UCH003_RS11970	COG1752	Esterase of the alpha-beta hydrolase superfamily
UCH003_RS12000	COG1834	amidinotransferase
UCH003_RS12010	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
UCH003_RS12020	COG0039	L-malate dehydrogenase activity
UCH003_RS12030	COG3290	protein histidine kinase activity
UCH003_RS12030	COG0840	transmembrane signaling receptor activity
UCH003_RS12055	COG2358	TRAP transporter, solute receptor (TAXI family
UCH003_RS12065	COG0731	radical SAM domain protein
UCH003_RS12070	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
UCH003_RS12080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
UCH003_RS12085	COG2204	response regulator
UCH003_RS12120	COG1040	competence protein
UCH003_RS12125	COG0481	GTPase activity
UCH003_RS12130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
UCH003_RS12150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UCH003_RS12160	COG0463	Glycosyl transferase, family 2
UCH003_RS12175	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
UCH003_RS12175	COG1776	CheC inhibitor of MCP methylation
UCH003_RS12180	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
UCH003_RS12185	COG1191	sigma factor activity
UCH003_RS12195	COG0455	bacterial-type flagellum organization
UCH003_RS12200	COG1419	protein localization to endoplasmic reticulum
UCH003_RS12205	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
UCH003_RS12210	COG0006	proline dipeptidase activity
UCH003_RS12215	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
UCH003_RS12220	COG0402	S-adenosylhomocysteine deaminase activity
UCH003_RS12225	COG0616	signal peptide processing
UCH003_RS12230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
UCH003_RS12235	COG2855	membrane
UCH003_RS12240	COG0583	DNA-binding transcription factor activity
UCH003_RS12245	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
UCH003_RS12250	COG0697	spore germination
UCH003_RS12255	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
UCH003_RS12290	COG1570	exodeoxyribonuclease VII activity
UCH003_RS12305	COG1227	inorganic diphosphatase activity
UCH003_RS12320	COG0811	peptide transport
UCH003_RS12325	COG0848	biopolymer transport protein
UCH003_RS12345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UCH003_RS12355	COG5002	protein histidine kinase activity
UCH003_RS12360	COG0745	RESPONSE REGULATOR receiver
UCH003_RS12365	COG3301	Polysulphide reductase, NrfD
UCH003_RS12370	COG0437	4 iron, 4 sulfur cluster binding
UCH003_RS12380	COG2199	diguanylate cyclase activity
UCH003_RS12380	COG2200	EAL domain
UCH003_RS12380	COG3287	FIST C domain
UCH003_RS12385	COG3301	Polysulphide reductase, NrfD
UCH003_RS12390	COG0437	4 iron, 4 sulfur cluster binding
UCH003_RS12395	COG0243	molybdopterin cofactor binding
UCH003_RS12405	COG3576	pyridoxamine 5-phosphate
UCH003_RS12415	COG3706	GGDEF domain
UCH003_RS12425	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
UCH003_RS12425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UCH003_RS12435	COG3258	Cytochrome c
UCH003_RS12445	COG0745	RESPONSE REGULATOR receiver
UCH003_RS12450	COG0642	Histidine kinase
UCH003_RS12455	COG1278	Cold shock
UCH003_RS12460	COG5001	Diguanylate cyclase
UCH003_RS12470	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
UCH003_RS12470	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
UCH003_RS12475	COG0779	Required for maturation of 30S ribosomal subunits
UCH003_RS12485	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
UCH003_RS12495	COG0083	homoserine kinase activity
UCH003_RS12505	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
UCH003_RS12510	COG0850	regulation of cytokinetic process
UCH003_RS12525	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
UCH003_RS12530	COG0157	Belongs to the NadC ModD family
UCH003_RS12535	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
UCH003_RS12540	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
UCH003_RS12550	COG0745	RESPONSE REGULATOR receiver
UCH003_RS12560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
UCH003_RS12565	COG0248	Ppx GppA phosphatase
UCH003_RS12570	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UCH003_RS12575	COG0287	Prephenate dehydrogenase
UCH003_RS12580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
UCH003_RS12590	COG0333	Belongs to the bacterial ribosomal protein bL32 family
UCH003_RS12600	COG0105	UTP biosynthetic process
UCH003_RS12615	COG0450	alkyl hydroperoxide reductase
UCH003_RS12620	COG0735	belongs to the Fur family
UCH003_RS12625	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
UCH003_RS12635	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
UCH003_RS12640	COG1766	The M ring may be actively involved in energy transduction
UCH003_RS12645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
UCH003_RS12650	COG1605	Chorismate mutase
UCH003_RS12650	COG0077	Prephenate dehydratase
UCH003_RS12655	COG0019	diaminopimelate decarboxylase activity
UCH003_RS12665	COG0193	aminoacyl-tRNA hydrolase activity
UCH003_RS12670	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
UCH003_RS12685	COG0560	Phosphoserine phosphatase
UCH003_RS12700	COG0835	chemotaxis
UCH003_RS12705	COG0784	Response regulator, receiver
UCH003_RS12705	COG2198	Histidine kinase
UCH003_RS12705	COG0643	Histidine kinase
UCH003_RS12710	COG0784	Response regulator, receiver
UCH003_RS12710	COG0835	chemotaxis
UCH003_RS12715	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UCH003_RS12720	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
UCH003_RS12725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
UCH003_RS12730	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UCH003_RS12735	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
UCH003_RS12740	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
UCH003_RS12760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
UCH003_RS12775	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
UCH003_RS12780	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UCH003_RS12785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
UCH003_RS12790	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
UCH003_RS12800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
UCH003_RS12815	COG0140	phosphoribosyl-ATP diphosphatase activity
UCH003_RS12815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
UCH003_RS12830	COG1242	4 iron, 4 sulfur cluster binding
UCH003_RS12835	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
UCH003_RS12840	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
UCH003_RS12845	COG0492	ferredoxin-NADP+ reductase activity
UCH003_RS12850	COG3118	belongs to the thioredoxin family
UCH003_RS12855	COG0792	nuclease activity
UCH003_RS12860	COG0460	homoserine dehydrogenase
UCH003_RS12865	COG0436	Aminotransferase
UCH003_RS12885	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
UCH003_RS12890	COG0254	rRNA binding
UCH003_RS12895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
UCH003_RS12905	COG0303	'Molybdopterin
UCH003_RS12910	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
UCH003_RS12915	COG0840	transmembrane signaling receptor activity
UCH003_RS12920	COG0840	transmembrane signaling receptor activity
UCH003_RS12940	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
UCH003_RS12945	COG1012	belongs to the aldehyde dehydrogenase family
UCH003_RS12955	COG1007	ATP synthesis coupled electron transport
UCH003_RS12960	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UCH003_RS12965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
UCH003_RS12970	COG0713	ATP synthesis coupled electron transport
UCH003_RS12975	COG0839	Belongs to the complex I subunit 6 family
UCH003_RS12980	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UCH003_RS12985	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
UCH003_RS13005	COG0649	NAD binding
UCH003_RS13015	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UCH003_RS13020	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UCH003_RS13030	COG0318	PFAM AMP-dependent synthetase and ligase
UCH003_RS13040	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
UCH003_RS13060	COG1121	(ABC) transporter
UCH003_RS13065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UCH003_RS13095	COG0765	amino acid transport
UCH003_RS13105	COG5002	protein histidine kinase activity
UCH003_RS13110	COG0745	RESPONSE REGULATOR receiver
UCH003_RS13120	COG0667	Aldo Keto reductase
UCH003_RS13125	COG0004	ammonium transporteR
UCH003_RS13140	COG0745	RESPONSE REGULATOR receiver
UCH003_RS13170	COG0840	transmembrane signaling receptor activity
UCH003_RS13175	COG2095	MarC family integral membrane protein
UCH003_RS13200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
UCH003_RS13205	COG1127	ABC transporter
UCH003_RS13225	COG0745	RESPONSE REGULATOR receiver
UCH003_RS13230	COG0642	Histidine kinase
UCH003_RS13255	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
UCH003_RS13275	COG1666	GTP binding
UCH003_RS13280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
UCH003_RS13285	COG0754	glutathionylspermidine amidase activity
UCH003_RS13300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
UCH003_RS13310	COG0348	domain, Protein
UCH003_RS13315	COG1275	C4-dicarboxylate transporter malic acid transport protein
UCH003_RS13325	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
UCH003_RS13330	COG0291	Belongs to the bacterial ribosomal protein bL35 family
UCH003_RS13335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
UCH003_RS13350	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
UCH003_RS13355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
UCH003_RS13370	COG0268	Binds directly to 16S ribosomal RNA
UCH003_RS13375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
UCH003_RS13385	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
UCH003_RS13390	COG0237	dephospho-CoA kinase activity
UCH003_RS13395	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
UCH003_RS13405	COG2257	FlhB HrpN YscU SpaS Family
UCH003_RS13420	COG1187	pseudouridine synthase activity
UCH003_RS13425	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
UCH003_RS13425	COG0517	IMP dehydrogenase activity
UCH003_RS13430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
UCH003_RS13435	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
UCH003_RS13440	COG0107	imidazoleglycerol-phosphate synthase activity
UCH003_RS13450	COG0820	rRNA (adenine-C2-)-methyltransferase activity
UCH003_RS13455	COG0179	Fumarylacetoacetate (FAA) hydrolase
UCH003_RS13460	COG0564	pseudouridine synthase activity
UCH003_RS13465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
UCH003_RS13470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UCH003_RS13475	COG1794	racemase activity, acting on amino acids and derivatives
UCH003_RS13490	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
UCH003_RS13500	COG0233	cytoplasmic translational termination
UCH003_RS13505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
UCH003_RS13530	COG1704	LemA family
UCH003_RS13535	COG1217	gtp-binding protein TYPA
UCH003_RS13545	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
UCH003_RS13550	COG1749	Flagellar hook protein flgE
UCH003_RS13555	COG1749	Flagellar hook protein flgE
UCH003_RS13560	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
UCH003_RS13565	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
