locus-tag	class	description
SHALO_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
SHALO_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
SHALO_RS00015	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
SHALO_RS00020	ENOG4105BZU	Histidine kinase
SHALO_RS00025	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
SHALO_RS00040	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
SHALO_RS00045	ENOG4105CEN	a g-specific adenine glycosylase
SHALO_RS00050	ENOG4108IJ7	Glycine betaine
SHALO_RS00055	ENOG4108HQS	Glycine betaine
SHALO_RS00060	ENOG4105GIJ	Glycine betaine
SHALO_RS00065	ENOG4105C2C	drug resistance transporter, Bcr CflA
SHALO_RS00075	ENOG4107GFK	fumarate
SHALO_RS00085	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SHALO_RS00090	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SHALO_RS00120	ENOG4105BZU	Histidine kinase
SHALO_RS00130	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS00155	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
SHALO_RS00160	ENOG4108MR7	Arylsulfotransferase
SHALO_RS00165	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS00185	ENOG4105C5I	Dehydrogenase
SHALO_RS00190	ENOG4108W2Y	isochorismatase
SHALO_RS00205	ENOG4105UEI	Transcriptional Regulator AraC Family
SHALO_RS00220	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
SHALO_RS00240	ENOG4105T16	Transcriptional regulator (AraC family)
SHALO_RS00250	ENOG4105IPS	esterase
SHALO_RS00255	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
SHALO_RS00265	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
SHALO_RS00270	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SHALO_RS00310	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
SHALO_RS00320	ENOG4105MZU	cell filamentation protein
SHALO_RS00410	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
SHALO_RS00435	ENOG4105C01	Dihydroxy-acid dehydratase
SHALO_RS00440	ENOG41081FY	multiple antibiotic resistance (MarC)-related
SHALO_RS00455	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
SHALO_RS00465	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
SHALO_RS00470	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
SHALO_RS00480	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SHALO_RS00490	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
SHALO_RS00495	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
SHALO_RS00505	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
SHALO_RS00510	ENOG4107QTF	adenylosuccinate lyase
SHALO_RS00515	ENOG4105EI2	Pseudouridine synthase
SHALO_RS00520	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
SHALO_RS00525	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
SHALO_RS00535	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
SHALO_RS00540	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
SHALO_RS00545	ENOG4105CN5	Metallo-Beta-Lactamase
SHALO_RS00550	ENOG4105C2X	Arabinose 5-phosphate isomerase
SHALO_RS00555	ENOG4105FE9	pseudouridine synthase
SHALO_RS00560	ENOG4105D1H	recombination factor protein RarA
SHALO_RS00570	ENOG4105VM1	flagellar
SHALO_RS00580	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
SHALO_RS00585	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
SHALO_RS00590	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
SHALO_RS00600	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
SHALO_RS00625	ENOG410813J	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
SHALO_RS00635	ENOG4105C22	threonyL-tRNA synthetase
SHALO_RS00640	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
SHALO_RS00650	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
SHALO_RS00655	ENOG4105C58	cytochrome c oxidase accessory protein ccog
SHALO_RS00665	ENOG41082DJ	30S ribosomal protein S21
SHALO_RS00675	ENOG4108UHV	Lipoprotein
SHALO_RS00680	ENOG4106032	Glutathionylspermidine synthase
SHALO_RS00685	ENOG4108VPT	UPF0234 protein
SHALO_RS00695	ENOG41080IJ	Diacylglycerol kinase
SHALO_RS00730	ENOG4108STX	response regulator
SHALO_RS00745	ENOG4107PE3	Mammalian cell entry related domain protein
SHALO_RS00750	ENOG4105DHJ	ABC, transporter
SHALO_RS00755	ENOG4105CY3	ABC transporter, permease
SHALO_RS00765	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
SHALO_RS00770	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS00780	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_RS00805	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_RS00810	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
SHALO_RS00815	ENOG4108YZA	Nitrogen regulatory protein pii
SHALO_RS00825	ENOG4105CPC	Aldo Keto reductase
SHALO_RS00835	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_RS00850	ENOG4105E5Q	amino acid AbC transporter
SHALO_RS00855	ENOG4106PMH	Extracellular solute-binding protein family 3
SHALO_RS00885	ENOG4105DIK	(ABC) transporter
SHALO_RS00905	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
SHALO_RS00915	ENOG4105CEY	Amp-dependent synthetase and ligase
SHALO_RS00920	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SHALO_RS00925	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHALO_RS00930	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_RS00935	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHALO_RS00940	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_RS00960	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
SHALO_RS00965	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_RS00975	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_RS00980	ENOG4105D65	subunit l
SHALO_RS00985	ENOG4105C8S	subunit m
SHALO_RS00990	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_RS01000	ENOG4105C26	Dehydrogenase
SHALO_RS01005	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
SHALO_RS01025	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS01035	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SHALO_RS01040	ENOG4107TH8	cina domain protein
SHALO_RS01050	ENOG4107YV6	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
SHALO_RS01055	ENOG41082DI	50s ribosomal protein l31
SHALO_RS01080	ENOG4105CHM	Aminotransferase
SHALO_RS01085	ENOG4105D6E	homoserine dehydrogenase
SHALO_RS01090	ENOG41082UM	UPF0102 protein
SHALO_RS01095	ENOG4105K63	Thioredoxin
SHALO_RS01100	ENOG4105C3M	thioredoxin reductase
SHALO_RS01105	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
SHALO_RS01115	ENOG4105N5T	Radical SAM Protein
SHALO_RS01130	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
SHALO_RS01140	ENOG4105CM2	brancheD-chain amino acid aminotransferase
SHALO_RS01150	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SHALO_RS01160	ENOG4105WPN	DNA integration recombination invertion protein
SHALO_RS01165	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
SHALO_RS01170	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SHALO_RS01175	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
SHALO_RS01190	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
SHALO_RS01220	ENOG4105CUZ	uba thif-type nad fad binding protein
SHALO_RS01225	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
SHALO_RS01230	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SHALO_RS01235	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
SHALO_RS01240	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
SHALO_RS01270	ENOG4105EAC	phosphoserine phosphatase
SHALO_RS01275	ENOG4107V25	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
SHALO_RS01280	ENOG4105CZX	twitching motility protein
SHALO_RS01290	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
SHALO_RS01300	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
SHALO_RS01305	ENOG4105CQC	Prephenate dehydratase
SHALO_RS01310	ENOG4105CIH	Imidazole acetol-phosphate transaminase
SHALO_RS01315	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
SHALO_RS01320	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
SHALO_RS01345	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
SHALO_RS01355	ENOG4105D3R	alkyl hydroperoxide reductase
SHALO_RS01360	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
SHALO_RS01370	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
SHALO_RS01385	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
SHALO_RS01390	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
SHALO_RS01400	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
SHALO_RS01405	ENOG4105C9X	ppx gppa phosphatase
SHALO_RS01410	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
SHALO_RS01420	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_RS01430	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
SHALO_RS01440	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
SHALO_RS01445	ENOG4105D00	flagellar biosynthetic protein flhB
SHALO_RS01455	ENOG4108K5P	(LipO)protein
SHALO_RS01460	ENOG4105VQJ	septum formation inhibitor
SHALO_RS01475	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
SHALO_RS01495	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
SHALO_RS01500	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
SHALO_RS01520	ENOG4105BZU	Histidine kinase
SHALO_RS01535	ENOG4105NQN	cytochrome C
SHALO_RS01555	ENOG4107QY8	reductase
SHALO_RS01560	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_RS01565	ENOG4105DVI	reductase, NrfD
SHALO_RS01570	ENOG4105BZU	Histidine kinase
SHALO_RS01575	ENOG4108J2R	molybdopterin oxidoreductase
SHALO_RS01580	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_RS01585	ENOG4105DVI	reductase, NrfD
SHALO_RS01595	ENOG4105BZU	Histidine kinase
SHALO_RS01605	ENOG4105CSA	Coproporphyrinogen iii oxidase
SHALO_RS01615	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
SHALO_RS01635	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
SHALO_RS01645	ENOG4105BZU	Histidine kinase
SHALO_RS01650	ENOG4105BZU	Histidine kinase
SHALO_RS01655	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
SHALO_RS01660	ENOG4105CHR	reductase
SHALO_RS01665	ENOG4105CF7	AraC family transcriptional regulator
SHALO_RS01670	ENOG4107RDF	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
SHALO_RS01675	ENOG4105DUM	transcriptional regulator, lysR family
SHALO_RS01680	ENOG4105HMI	Membrane
SHALO_RS01685	ENOG4108V06	Glutathione peroxidase
SHALO_RS01700	ENOG4108Z86	Glutamine amidotransferase
SHALO_RS01705	ENOG4107RNH	Outer membrane receptor FepA
SHALO_RS01720	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
SHALO_RS01755	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_RS01795	ENOG4108BGM	Quinol dehydrogenase periplasmic component
SHALO_RS01815	ENOG4105BZU	Histidine kinase
SHALO_RS01820	ENOG4107VQW	regulatoR
SHALO_RS01825	ENOG4105VBD	cytochrome C, class I
SHALO_RS01835	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_RS01870	ENOG4108V06	Glutathione peroxidase
SHALO_RS01890	ENOG4108JYZ	YitT family
SHALO_RS01900	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
SHALO_RS01905	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
SHALO_RS01910	ENOG4105DC7	peptidase M24
SHALO_RS01915	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SHALO_RS01920	ENOG4105FZW	flagellar biosynthesis regulator FlhF
SHALO_RS01925	ENOG4107R21	site-determining protein
SHALO_RS01935	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SHALO_RS01940	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
SHALO_RS01945	ENOG4105DD5	Flagellar motor switch protein
SHALO_RS01950	ENOG4108URH	decarboxylase
SHALO_RS01960	ENOG4105CKK	Glycosyl transferase, family 2
SHALO_RS01970	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SHALO_RS01975	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
SHALO_RS01990	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
SHALO_RS01995	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
SHALO_RS02000	ENOG4105MJ2	Competence protein
SHALO_RS02035	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
SHALO_RS02050	ENOG41082XB	radical SAM domain protein
SHALO_RS02060	ENOG4105H1G	trap transporter solute receptor taxi family
SHALO_RS02070	ENOG4105DFP	Integrase
SHALO_RS02075	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
SHALO_RS02135	ENOG4108JJA	ABC, transporter
SHALO_RS02140	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
SHALO_RS02185	ENOG4107WZZ	SMC domain protein
SHALO_RS02215	ENOG4107QRI	Phosphoketolase
SHALO_RS02225	ENOG4106V2I	dimethylaminohydrolase
SHALO_RS02230	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
SHALO_RS02235	ENOG4107R7Y	intracellular protease Pfpi family
SHALO_RS02265	ENOG4105BZU	Histidine kinase
SHALO_RS02280	ENOG4105K63	Thioredoxin
SHALO_RS02315	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
SHALO_RS02320	ENOG4105EMU	Dehydrogenase
SHALO_RS02335	ENOG4105CP9	extracellular ligand-binding receptor
SHALO_RS02340	ENOG4105C32	Amino acid ABC transporter (Permease)
SHALO_RS02345	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
SHALO_RS02350	ENOG4105C0Z	ABC transporter
SHALO_RS02355	ENOG4108IV0	ABC, transporter
SHALO_RS02360	ENOG4105C26	Dehydrogenase
SHALO_RS02370	ENOG410802Z	Protein of unknown function (DUF328)
SHALO_RS02395	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
SHALO_RS02410	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
SHALO_RS02415	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
SHALO_RS02430	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
SHALO_RS02445	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
SHALO_RS02450	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
SHALO_RS02455	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
SHALO_RS02460	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
SHALO_RS02465	ENOG4108UMI	ABC transporter, permease
SHALO_RS02470	ENOG4105D01	(LipO)protein
SHALO_RS02485	ENOG4105FDR	Membrane
SHALO_RS02505	ENOG4108J2R	molybdopterin oxidoreductase
SHALO_RS02515	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_RS02530	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS02535	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SHALO_RS02545	ENOG4108IEH	NADH dehydrogenase subunit g
SHALO_RS02550	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
SHALO_RS02565	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_RS02570	ENOG4105D65	subunit l
SHALO_RS02580	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_RS02600	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_RS02605	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_RS02610	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHALO_RS02625	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
SHALO_RS02645	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
SHALO_RS02655	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
SHALO_RS02665	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
SHALO_RS02670	ENOG4105D52	delta-aminolevulinic acid dehydratase
SHALO_RS02675	ENOG4105DBV	ornithine carbamoyltransferase
SHALO_RS02680	ENOG4105T1H	UPF0763 protein
SHALO_RS02685	ENOG4105D4P	Coproporphyrinogen iii oxidase
SHALO_RS02690	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
SHALO_RS02715	ENOG4105K4U	addiction module toxin, RelE StbE family
SHALO_RS02720	ENOG4105BZU	Histidine kinase
SHALO_RS02725	ENOG4105F27	Major Facilitator
SHALO_RS02730	ENOG4105K5B	UPF0225 protein
SHALO_RS02745	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
SHALO_RS02750	ENOG4108S24	Fumarate reduCtase
SHALO_RS02755	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
SHALO_RS02760	ENOG4105E33	succinate dehydrogenase
SHALO_RS02770	ENOG410890F	Dynamin family
SHALO_RS02780	ENOG4105F4G	Membrane
SHALO_RS02785	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
SHALO_RS02790	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
SHALO_RS02800	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
SHALO_RS02815	ENOG4105CE9	30S ribosomal protein S2
SHALO_RS02830	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
SHALO_RS02840	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
SHALO_RS02850	ENOG4105C75	arginyL-tRNA synthetase
SHALO_RS02860	ENOG4105BZU	Histidine kinase
SHALO_RS02875	ENOG4105I3K	Ferric uptake regulator, Fur family
SHALO_RS02880	ENOG4105CA0	peroxidase
SHALO_RS02900	ENOG4105CP7	Triose-phosphate isomerase
SHALO_RS02905	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
SHALO_RS02915	ENOG4105CHV	Transcription elongation factor NusA
SHALO_RS02925	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
SHALO_RS02950	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
SHALO_RS02955	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
SHALO_RS02960	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
SHALO_RS02965	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
SHALO_RS02990	ENOG4107QMP	dna polymerase iii subunits gamma and tau
SHALO_RS02995	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
SHALO_RS03000	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
SHALO_RS03005	ENOG4105BZU	Histidine kinase
SHALO_RS03010	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
SHALO_RS03035	ENOG4105CSR	polyphosphate kinase 2
SHALO_RS03045	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_RS03050	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_RS03060	ENOG4108YXA	Membrane
SHALO_RS03065	ENOG4105C1J	atp-dependent rna helicase
SHALO_RS03070	ENOG4105C6Z	Gluconate
SHALO_RS03075	ENOG4105DDY	UPF0142 protein ycaO
SHALO_RS03080	ENOG41062JF	Transcriptional regulator
SHALO_RS03085	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
SHALO_RS03095	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
SHALO_RS03100	ENOG4107YZX	Universal stress protein
SHALO_RS03125	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
SHALO_RS03130	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
SHALO_RS03135	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
SHALO_RS03145	ENOG4105VXP	Protein of unknown function DUF86
SHALO_RS03210	ENOG4105C32	Amino acid ABC transporter (Permease)
SHALO_RS03215	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
SHALO_RS03220	ENOG4105C0Z	ABC transporter
SHALO_RS03225	ENOG4108IV0	ABC, transporter
SHALO_RS03230	ENOG4105CRE	cytochrome C
SHALO_RS03270	ENOG4105CEV	competence damage-inducible protein
SHALO_RS03275	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
SHALO_RS03280	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
SHALO_RS03285	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
SHALO_RS03290	ENOG4105DWV	Homoserine O-trans-acetylase
SHALO_RS03305	ENOG4105D06	uba thif-type nad fad binding protein
SHALO_RS03310	ENOG4105CHM	Aminotransferase
SHALO_RS03315	ENOG4105DFU	Cell wall formation (By similarity)
SHALO_RS03325	ENOG4105C98	muts2 protein
SHALO_RS03330	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
SHALO_RS03335	ENOG4105KME	endoribonuclease L-psp
SHALO_RS03340	ENOG4107RSR	Malate quinone oxidoreductase
SHALO_RS03355	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
SHALO_RS03360	ENOG4105CN1	protease
SHALO_RS03380	ENOG4105K46	50S ribosomal protein l27
SHALO_RS03385	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SHALO_RS03390	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
SHALO_RS03395	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
SHALO_RS03405	ENOG4107QJE	Chromosome Partitioning Protein
SHALO_RS03410	ENOG4105FA0	parb-like partition protein
SHALO_RS03420	ENOG4105YF2	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
SHALO_RS03425	ENOG4105PQH	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
SHALO_RS03430	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
SHALO_RS03435	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
SHALO_RS03440	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
SHALO_RS03445	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
SHALO_RS03450	ENOG4105E02	MotA TolQ exbB proton channel
SHALO_RS03455	ENOG4105M8F	Biopolymer transport protein exbD tolR
SHALO_RS03465	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
SHALO_RS03470	ENOG4105UYK	outer membrane protein a
SHALO_RS03480	ENOG4108YZY	peptidylprolyl cis-trans isomerase
SHALO_RS03490	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
SHALO_RS03495	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
SHALO_RS03500	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
SHALO_RS03510	ENOG4105CBC	glutamate synthase
SHALO_RS03515	ENOG4105BZ8	glutamate synthase
SHALO_RS03525	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
SHALO_RS03530	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
SHALO_RS03535	ENOG4105SCY	DNAK suppressor
SHALO_RS03545	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
SHALO_RS03565	ENOG4105DD5	Flagellar motor switch protein
SHALO_RS03580	ENOG4108Z0R	Transferase
SHALO_RS03590	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
SHALO_RS03595	ENOG4108MTT	Glutamate-rich protein grpB
SHALO_RS03600	ENOG4108UYN	gCN5-related N-acetyltransferase
SHALO_RS03610	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
SHALO_RS03620	ENOG4105C85	amino acid
SHALO_RS03625	ENOG4105HF0	Membrane
SHALO_RS03630	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
SHALO_RS03635	ENOG4105CK2	sodium dicarboxylate symporter
SHALO_RS03640	ENOG4105CK2	sodium dicarboxylate symporter
SHALO_RS03650	ENOG4105C2M	dna polymerase I
SHALO_RS03655	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
SHALO_RS03665	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SHALO_RS03690	ENOG4105C4M	(Ubiquinol oxidase) subunit I
SHALO_RS03695	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
SHALO_RS03710	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
SHALO_RS03715	ENOG4105BZU	Histidine kinase
SHALO_RS03725	ENOG4105CEY	Amp-dependent synthetase and ligase
SHALO_RS03730	ENOG4105E2X	shikimate dehydrogenase
SHALO_RS03735	ENOG4105CRQ	synthase (Component I)
SHALO_RS03750	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
SHALO_RS03755	ENOG4105CRK	lysyL-tRNA synthetase
SHALO_RS03770	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
SHALO_RS03775	ENOG4105CZX	twitching motility protein
SHALO_RS03780	ENOG410855J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
SHALO_RS03790	ENOG4108TX7	
SHALO_RS03805	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
SHALO_RS03810	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_RS03815	ENOG4105BZU	Histidine kinase
SHALO_RS03830	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
SHALO_RS03840	ENOG4108IYU	L-aspartate oxidase
SHALO_RS03845	ENOG4105DN9	Na H antiporter
SHALO_RS03850	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SHALO_RS03875	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
SHALO_RS03980	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
SHALO_RS03995	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
SHALO_RS04000	ENOG4105D9Q	decarboxylase (Beta subunit)
SHALO_RS04005	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
SHALO_RS04010	ENOG4105CH7	arginosuccinase
SHALO_RS04015	ENOG4105K59	histidine triad (HIT) protein
SHALO_RS04020	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
SHALO_RS04025	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
SHALO_RS04030	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
SHALO_RS04035	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
SHALO_RS04040	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
SHALO_RS04050	ENOG4108JQ1	Dehydrogenase
SHALO_RS04060	ENOG4107V40	secretion protein, HlyD family
SHALO_RS04070	ENOG4105BZS	acriflavin resistance protein
SHALO_RS04080	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
SHALO_RS04085	ENOG4107S0N	DJ-1 family
SHALO_RS04090	ENOG4108QAF	Methyl-accepting chemotaxis sensory transducer
SHALO_RS04095	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
SHALO_RS04110	ENOG4105CBX	hi0933 family
SHALO_RS04125	ENOG4105BZU	Histidine kinase
SHALO_RS04130	ENOG4108YXA	Membrane
SHALO_RS04135	ENOG4106492	Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO (By similarity)
SHALO_RS04150	ENOG4105BZU	Histidine kinase
SHALO_RS04165	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SHALO_RS04175	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
SHALO_RS04180	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SHALO_RS04185	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
SHALO_RS04185	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
SHALO_RS04195	ENOG4105C0B	DNA polymerase III (alpha subunit)
SHALO_RS04215	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
SHALO_RS04220	ENOG4105C1A	potassium transporter peripheral membrane
SHALO_RS04235	ENOG4105CNI	cell division protein FtsW
SHALO_RS04240	ENOG4105C34	Pseudouridine synthase
SHALO_RS04250	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
SHALO_RS04275	ENOG410692R	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
SHALO_RS04280	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
SHALO_RS04285	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
SHALO_RS04290	ENOG4105EA8	2-Nitropropane dioxygenase
SHALO_RS04295	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
SHALO_RS04305	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
SHALO_RS04310	ENOG4105C9M	aspartyl-trna synthetase
SHALO_RS04325	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
SHALO_RS04330	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
SHALO_RS04335	ENOG4105DAA	L-lactate
SHALO_RS04340	ENOG4105BZU	Histidine kinase
SHALO_RS04345	ENOG4105F8V	Hydrolase, tatD family
SHALO_RS04350	ENOG41068JE	domain protein
SHALO_RS04355	ENOG4105K6T	rare lipoprotein A
SHALO_RS04360	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
SHALO_RS04365	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
SHALO_RS04380	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
SHALO_RS04395	ENOG4105CJN	penicillin-binding protein
SHALO_RS04415	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
SHALO_RS04425	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
SHALO_RS04450	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
SHALO_RS04455	ENOG4105CX6	glutaminyL-tRNA synthetase
SHALO_RS04470	ENOG4105WH1	Two component transcriptional regulator luxr family
SHALO_RS04475	ENOG4107QPK	)-transporter
SHALO_RS04485	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS04495	ENOG4105DY9	regulatoR
SHALO_RS04500	ENOG4105RAK	Histidine kinase
SHALO_RS04510	ENOG4105C5Q	Transcriptional regulator
SHALO_RS04515	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
SHALO_RS04520	ENOG4105E33	succinate dehydrogenase
SHALO_RS04525	ENOG41086B8	CoB-CoM heterodisulfide reductase
SHALO_RS04535	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS04550	ENOG4108W6G	cytochrome C
SHALO_RS04555	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
SHALO_RS04560	ENOG4105CRE	cytochrome C
SHALO_RS04580	ENOG4105MJ9	esterase
SHALO_RS04610	ENOG4108C33	Resolvase
SHALO_RS04615	ENOG41067MG	lrgb family
SHALO_RS04635	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
SHALO_RS04645	ENOG4108N5C	SNARE associated Golgi protein-related protein
SHALO_RS04665	ENOG4105EMK	carboxylate amino acid amine transporter
SHALO_RS04675	ENOG4108CIP	transcriptional regulator
SHALO_RS04690	ENOG4107XVH	Transcriptional regulator
SHALO_RS04710	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
SHALO_RS04725	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
SHALO_RS04745	ENOG4105BZ9	Cytochrome C oxidase, subunit I
SHALO_RS04770	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
SHALO_RS04775	ENOG4108BGM	Quinol dehydrogenase periplasmic component
SHALO_RS04780	ENOG4105GXZ	Ferredoxin-type protein NapH
SHALO_RS04785	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
SHALO_RS04790	ENOG4108ZNS	ferredoxin-type protein NapF
SHALO_RS04805	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SHALO_RS04810	ENOG4105C3G	gtp-binding protein
SHALO_RS04840	ENOG4108AEY	RNA polymerase sigma factor
SHALO_RS04855	ENOG4108J2R	molybdopterin oxidoreductase
SHALO_RS04870	ENOG4105ETX	regulatoR
SHALO_RS04885	ENOG4105VBD	cytochrome C, class I
SHALO_RS04890	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_RS04895	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_RS04905	ENOG4107SDU	Methyl-accepting chemotaxis
SHALO_RS04915	ENOG4105BZU	Histidine kinase
SHALO_RS04920	ENOG4105DJ4	phosphatidylserine decarboxylase
SHALO_RS04925	ENOG4105C1J	atp-dependent rna helicase
SHALO_RS04935	ENOG4105WWK	YheO domain protein
SHALO_RS04940	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
SHALO_RS04950	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
SHALO_RS04960	ENOG4108NIW	Leucine export protein LeuE
SHALO_RS04965	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_RS04985	ENOG4105ENE	Histidine kinase
SHALO_RS04995	ENOG4105EUZ	Beta-lactamase domain protein
SHALO_RS05000	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
SHALO_RS05010	ENOG4105CDY	transcriptional regulatory protein
SHALO_RS05020	ENOG4105H1G	trap transporter solute receptor taxi family
SHALO_RS05035	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
SHALO_RS05045	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
SHALO_RS05050	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
SHALO_RS05060	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SHALO_RS05110	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SHALO_RS05205	ENOG4108RH0	Crea protein
SHALO_RS05210	ENOG4105BZU	Histidine kinase
SHALO_RS05220	ENOG4107VQW	regulatoR
SHALO_RS05250	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
SHALO_RS05255	ENOG4108Q9V	regulatoR
SHALO_RS05290	ENOG41084S7	Plasmid maintenance system antidote protein
SHALO_RS05335	ENOG4105DWK	Membrane
SHALO_RS05340	ENOG4107XM3	UPF0442 protein
SHALO_RS05345	ENOG4105W3S	hemerythrin-like, metal-binding protein
SHALO_RS05350	ENOG4105C59	p-type ATPase
SHALO_RS05370	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
SHALO_RS05385	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
SHALO_RS05395	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS05400	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS05405	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
SHALO_RS05420	ENOG4108UT2	hemolysin iii
SHALO_RS05430	ENOG410829K	Lysine exporter protein (Lyse ygga)
SHALO_RS05435	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
SHALO_RS05440	ENOG4107QR9	Iron-sulfur cluster binding protein
SHALO_RS05445	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
SHALO_RS05450	ENOG410631K	Membrane
SHALO_RS05470	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
SHALO_RS05480	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
SHALO_RS05490	ENOG4105D0M	Protease HtpX homolog
SHALO_RS05510	ENOG4105BZU	Histidine kinase
SHALO_RS05515	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
SHALO_RS05520	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
SHALO_RS05525	ENOG4108VD1	dedA family
SHALO_RS05530	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
SHALO_RS05535	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
SHALO_RS05545	ENOG4108YZG	isomerase
SHALO_RS05550	ENOG4108Z4T	Peptidase M50
SHALO_RS05555	ENOG4105C3F	Signal peptidase i
SHALO_RS05560	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
SHALO_RS05570	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
SHALO_RS05585	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
SHALO_RS05595	ENOG4105CB5	ATP-dependent DNA helicase recG
SHALO_RS05625	ENOG410821Z	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
SHALO_RS05630	ENOG410901F	(LipO)protein
SHALO_RS05635	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
SHALO_RS05640	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
SHALO_RS05645	ENOG4108UUM	single-stranded DNA-binding protein
SHALO_RS05655	ENOG4108VMB	DNA polymerase III subunit delta'
SHALO_RS05660	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
SHALO_RS05675	ENOG4107QMS	site-determining protein
SHALO_RS05680	ENOG41084TB	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
SHALO_RS05695	ENOG4107TSN	permease
SHALO_RS05700	ENOG4108UIN	ybak prolyl-trna synthetase associated region
SHALO_RS05715	ENOG4105EJQ	L-serine dehydratase
SHALO_RS05720	ENOG4105GSH	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
SHALO_RS05725	ENOG4105EN6	Membrane
SHALO_RS05730	ENOG4105C8Y	Acetylornithine aminotransferase
SHALO_RS05740	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
SHALO_RS05745	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
SHALO_RS05750	ENOG4105X6C	Flagellar basal body-associated protein FliL
SHALO_RS05755	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
SHALO_RS05760	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
SHALO_RS05775	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
SHALO_RS05780	ENOG4105BZ1	(ABC) transporter
SHALO_RS05790	ENOG4108VD1	dedA family
SHALO_RS05800	ENOG4105C09	Bile acid
SHALO_RS05805	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
SHALO_RS05815	ENOG4105EQD	regulatoR
SHALO_RS05820	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_RS05825	ENOG4105BZU	Histidine kinase
SHALO_RS05845	ENOG4108Z66	YbaK ebsC protein
SHALO_RS05920	ENOG4105GR3	Histidine kinase
SHALO_RS05925	ENOG4107RN3	metallophosphoesterase
SHALO_RS05930	ENOG4108YYC	ycei family
SHALO_RS05945	ENOG4107XPZ	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
SHALO_RS05960	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
SHALO_RS05990	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
SHALO_RS05995	ENOG4107YD3	Thioesterase
SHALO_RS06005	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
SHALO_RS06020	ENOG4107S73	homocitrate synthase
SHALO_RS06030	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_RS06040	ENOG4105BZU	Histidine kinase
SHALO_RS06050	ENOG4108STX	response regulator
SHALO_RS06055	ENOG4105CNW	domain protein
SHALO_RS06070	ENOG4105D0B	Nitrogenase protein alpha chain
SHALO_RS06080	ENOG4108J5H	Homocysteine s-methyltransferase
SHALO_RS06085	ENOG4105C26	Dehydrogenase
SHALO_RS06090	ENOG4105EGS	Mechanosensitive ion channel
SHALO_RS06110	ENOG4108VQE	nitrogen fixation protein
SHALO_RS06120	ENOG4106C8Q	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
SHALO_RS06125	ENOG4105XV5	nifz family
SHALO_RS06135	ENOG4105KXW	Ferredoxin
SHALO_RS06140	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SHALO_RS06150	ENOG4108Z7F	N-acetyltransferase
SHALO_RS06170	ENOG4105F5P	DNA-damage-inducible protein d
SHALO_RS06200	ENOG4105BZU	Histidine kinase
SHALO_RS06225	ENOG4108VKG	metal-dependent hydrolase
SHALO_RS06250	ENOG4105JAB	phenazine biosynthesis protein, phzf family
SHALO_RS06290	ENOG4105BZU	Histidine kinase
SHALO_RS06295	ENOG4105BZU	Histidine kinase
SHALO_RS06300	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
SHALO_RS06340	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS06345	ENOG4107QY8	reductase
SHALO_RS06360	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
SHALO_RS06365	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
SHALO_RS06380	ENOG4105RRV	Inherit from COG: copper resistance
SHALO_RS06385	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
SHALO_RS06395	ENOG4105D0B	Nitrogenase protein alpha chain
SHALO_RS06410	ENOG4108TQ9	Histidine kinase
SHALO_RS06425	ENOG4108NEV	two component transcriptional regulator, LytTR family
SHALO_RS06460	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
SHALO_RS06505	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS06510	ENOG4105BZ8	glutamate synthase
SHALO_RS06515	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
SHALO_RS06520	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
SHALO_RS06525	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
SHALO_RS06530	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
SHALO_RS06540	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_RS06570	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
SHALO_RS06580	ENOG4108YZY	peptidylprolyl cis-trans isomerase
SHALO_RS06590	ENOG4105CKI	cobalamin synthesis protein
SHALO_RS06595	ENOG4105VCD	cytoplasmic protein
SHALO_RS06600	ENOG4105D22	carbon starvation protein
SHALO_RS06610	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
SHALO_RS06615	ENOG41084IN	nitrogen fixation protein
SHALO_RS06645	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
SHALO_RS06650	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
SHALO_RS06665	ENOG4105BZU	Histidine kinase
SHALO_RS06675	ENOG4105BZU	Histidine kinase
SHALO_RS06695	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
SHALO_RS06705	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
SHALO_RS06715	ENOG4105DHT	Metal Dependent Phosphohydrolase
SHALO_RS06725	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
SHALO_RS06735	ENOG4105C5H	ABC transporter
SHALO_RS06740	ENOG4108SEK	ompa motb domain protein
SHALO_RS06745	ENOG4105E14	MotA TolQ exbB proton channel
SHALO_RS06750	ENOG4107XI7	Tetr family transcriptional regulator
SHALO_RS06765	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
SHALO_RS06780	ENOG4108RCM	Nitroreductase
SHALO_RS06785	ENOG4108RCM	Nitroreductase
SHALO_RS06800	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
SHALO_RS06825	ENOG4105DZS	Phenylacetate-CoA ligase
SHALO_RS06855	ENOG4107TPX	flagellar hook-associated
SHALO_RS06870	ENOG4106H78	methyltransferase
SHALO_RS06875	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
SHALO_RS06880	ENOG4105YKR	
SHALO_RS06900	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
SHALO_RS06910	ENOG4105CHH	sulfate transporter
SHALO_RS06915	ENOG4105VSH	4-oxalocrotonate tautomerase
SHALO_RS06940	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
SHALO_RS06955	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
SHALO_RS06965	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
SHALO_RS06980	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
SHALO_RS06985	ENOG4105CN7	Flagellar biosynthetic protein FliP
SHALO_RS06990	ENOG4105DSB	aldose 1-epimerase
SHALO_RS06995	ENOG4105KVH	Transcriptional regulator
SHALO_RS07000	ENOG4105NF4	modulator of drug activity
SHALO_RS07015	ENOG4107PU6	Membrane
SHALO_RS07020	ENOG4105CCT	upf0313 protein
SHALO_RS07025	ENOG4107QP8	phosphohexose isomerase
SHALO_RS07045	ENOG4105DPX	Hydrogenase, large subunit
SHALO_RS07050	ENOG4105E3S	small subunit
SHALO_RS07055	ENOG4105DPX	Hydrogenase, large subunit
SHALO_RS07060	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
SHALO_RS07065	ENOG4108USZ	hydrogenase
SHALO_RS07070	ENOG4108P97	
SHALO_RS07080	ENOG4105MRR	Transcriptional regulator (By similarity)
SHALO_RS07085	ENOG4105E0K	tonB-dependent siderophore receptor
SHALO_RS07105	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
SHALO_RS07110	ENOG4105CQS	hydrogenase expression formation protein HypD
SHALO_RS07115	ENOG4105C45	hydrogenase expression formation protein (HypE)
SHALO_RS07125	ENOG4107TCE	N-acetyltransferase
SHALO_RS07130	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SHALO_RS07145	ENOG4105E9K	Isocitrate dehydrogenase
SHALO_RS07150	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
SHALO_RS07155	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
SHALO_RS07160	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
SHALO_RS07170	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
SHALO_RS07175	ENOG4107QK6	Thiamine pyrophosphate
SHALO_RS07200	ENOG4105C9Q	fumarate hydratase class II
SHALO_RS07215	ENOG41081FY	multiple antibiotic resistance (MarC)-related
SHALO_RS07230	ENOG4105DFA	alanine racemase domain protein
SHALO_RS07235	ENOG4105DZP	Membrane-associated zinc metalloprotease
SHALO_RS07240	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
SHALO_RS07245	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
SHALO_RS07250	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
SHALO_RS07260	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
SHALO_RS07265	ENOG4105BZ1	(ABC) transporter
SHALO_RS07270	ENOG4105C8N	cysteinyl-tRNA synthetase
SHALO_RS07275	ENOG4105CJR	Integral membrane protein (MviN
SHALO_RS07285	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
SHALO_RS07290	ENOG4105CPF	Cell wall formation (By similarity)
SHALO_RS07310	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
SHALO_RS07315	ENOG4105C6K	Malic enzyme
SHALO_RS07320	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
SHALO_RS07345	ENOG4107QHF	type ii secretion system protein e
SHALO_RS07360	ENOG4105GVR	general secretion pathway protein D
SHALO_RS07380	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
SHALO_RS07385	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
SHALO_RS07390	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
SHALO_RS07405	ENOG4105CDH	Citrulline--aspartate ligase
SHALO_RS07410	ENOG410854I	s4 domain protein
SHALO_RS07415	ENOG4107QYG	anthranilate phosphoribosyltransferase
SHALO_RS07420	ENOG4105K8N	protein family UPF0079, ATPase
SHALO_RS07425	ENOG4108IUZ	ABC transporter
SHALO_RS07430	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SHALO_RS07455	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS07475	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_RS07490	ENOG4107YTP	response regulator receiver protein
SHALO_RS07505	ENOG4107EFR	Flavocytochrome c
SHALO_RS07550	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_RS07580	ENOG4108BGM	Quinol dehydrogenase periplasmic component
SHALO_RS07590	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
SHALO_RS07600	ENOG4108YZT	Adenosylcobinamide kinase
SHALO_RS07620	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
SHALO_RS07630	ENOG4107PPM	cobalt chelatase
SHALO_RS07635	ENOG4105EHG	Permease protein
SHALO_RS07640	ENOG4105E0A	ABC, transporter
SHALO_RS07650	ENOG41081F0	Precorrin-8x methylmutase
SHALO_RS07655	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
SHALO_RS07665	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
SHALO_RS07670	ENOG4105DVK	Precorrin-2 c20-methyltransferase
SHALO_RS07675	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
SHALO_RS07680	ENOG4108P62	biosynthesis protein (CbiG)
SHALO_RS07685	ENOG4105E4R	Precorrin-3B C17-methyltransferase
SHALO_RS07695	ENOG4108JTQ	reductase
SHALO_RS07700	ENOG4105BZ1	(ABC) transporter
SHALO_RS07705	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
SHALO_RS07715	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
SHALO_RS07720	ENOG4108IG5	Transcriptional regulator
SHALO_RS07835	ENOG410841J	DNA-binding protein Hu
SHALO_RS07845	ENOG4105CNU	cell division protein FtsK
SHALO_RS07850	ENOG4107QIJ	Aconitate hydratase 2
SHALO_RS07855	ENOG4108YZY	peptidylprolyl cis-trans isomerase
SHALO_RS07860	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
SHALO_RS07865	ENOG4105C6X	Major Facilitator
SHALO_RS07885	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
SHALO_RS07890	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS07895	ENOG4105K4P	CoA-binding domain protein
SHALO_RS07900	ENOG4105C7B	Threonine dehydratase
SHALO_RS07910	ENOG4105CDA	abc transporter atp-binding protein
SHALO_RS07915	ENOG4105DRP	amino acid AbC transporter
SHALO_RS07920	ENOG4105EZ7	amino acid ABC transporter
SHALO_RS07925	ENOG4107QXX	ABC transporter
SHALO_RS07930	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
SHALO_RS07940	ENOG4107T5V	SNARE associated Golgi
SHALO_RS07950	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_RS07955	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
SHALO_RS07970	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
SHALO_RS07975	ENOG4105QTX	Pfam:UPF0153
SHALO_RS07985	ENOG4105DK0	Indole-3-glycerol phosphate synthase
SHALO_RS07995	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
SHALO_RS08005	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
SHALO_RS08025	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
SHALO_RS08030	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
SHALO_RS08045	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
SHALO_RS08060	ENOG4105C7K	acetolactate synthase
SHALO_RS08065	ENOG4108ZP8	Acetolactate synthase small subunit
SHALO_RS08070	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
SHALO_RS08080	ENOG4105BZ8	glutamate synthase
SHALO_RS08085	ENOG4105CHM	Aminotransferase
SHALO_RS08090	ENOG4105D0B	Nitrogenase protein alpha chain
SHALO_RS08095	ENOG4108JUA	Transcriptional regulator
SHALO_RS08105	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
SHALO_RS08110	ENOG4105SJ7	Fe-only nitrogenase subunit delta
SHALO_RS08115	ENOG4107V0H	Nitrogenase protein alpha chain
SHALO_RS08120	ENOG4105D7W	serine acetyltransferase
SHALO_RS08125	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
SHALO_RS08130	ENOG4105CUT	histidyl-tRNA synthetase
SHALO_RS08135	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
SHALO_RS08140	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
SHALO_RS08145	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
SHALO_RS08165	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
SHALO_RS08170	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
SHALO_RS08190	ENOG4107QPK	)-transporter
SHALO_RS08200	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
SHALO_RS08205	ENOG4105DVM	PP-loop domain protein
SHALO_RS08210	ENOG4105C8M	UPF0272 protein
SHALO_RS08215	ENOG4105QUH	Domain of unknown function (DUF2088)
SHALO_RS08220	ENOG4107GFK	fumarate
SHALO_RS08230	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
SHALO_RS08265	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
SHALO_RS08270	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
SHALO_RS08280	ENOG4105D49	3-dehydroquinate synthase
SHALO_RS08290	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
SHALO_RS08315	ENOG4105DEN	Luciferase family
SHALO_RS08325	ENOG4105CHR	reductase
SHALO_RS08335	ENOG4105D29	Helix-turn-helix type 11 domain protein
SHALO_RS08340	ENOG4105FE9	pseudouridine synthase
SHALO_RS08350	ENOG4105C7K	acetolactate synthase
SHALO_RS08365	ENOG4105CSV	Glutaminase
SHALO_RS08370	ENOG4105BZU	Histidine kinase
SHALO_RS08385	ENOG4107Z3H	Transcriptional regulator, TetR family
SHALO_RS08415	ENOG4108RAC	Rubrerythrin
SHALO_RS08425	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
SHALO_RS08430	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
SHALO_RS08445	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
SHALO_RS08450	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
SHALO_RS08455	ENOG4105EAH	synthase
SHALO_RS08480	ENOG4105C6T	cysteine synthase
SHALO_RS08485	ENOG4105BZU	Histidine kinase
SHALO_RS08490	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
SHALO_RS08495	ENOG4105CH5	extracellular solute-binding protein, family 7
SHALO_RS08500	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
SHALO_RS08510	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
SHALO_RS08520	ENOG4105D2N	Aldolase
SHALO_RS08525	ENOG4105EIN	peptidylprolyl cis-trans isomerase
SHALO_RS08540	ENOG4105CIN	aminoacyl-histidine dipeptidase
SHALO_RS08550	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
SHALO_RS08565	ENOG4105C4K	Nad synthetase
SHALO_RS08570	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SHALO_RS08580	ENOG4105CAS	nag kinase
SHALO_RS08585	ENOG4107QID	Threonine synthase
SHALO_RS08590	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
SHALO_RS08605	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
SHALO_RS08610	ENOG4105CSR	polyphosphate kinase 2
SHALO_RS08615	ENOG4105CFG	Acts as a chaperone (By similarity)
SHALO_RS08620	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SHALO_RS08625	ENOG4108122	heat-inducible transcription repressor
SHALO_RS08635	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
SHALO_RS08640	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
SHALO_RS08645	ENOG4105D7B	Flagellar biosynthesis protein flha
SHALO_RS08650	ENOG4108KA0	Inherit from COG: Phosphoesterase, DHHA1
SHALO_RS08660	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
SHALO_RS08665	ENOG4106TD9	Diguanylate cyclase
SHALO_RS08670	ENOG4105DTN	riboflavin biosynthesis protein ribF
SHALO_RS08675	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
SHALO_RS08680	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
SHALO_RS08685	ENOG4105EJ9	Membrane
SHALO_RS08695	ENOG4105EEI	dihydropteroate synthase
SHALO_RS08710	ENOG4105CFH	Aspartokinase
SHALO_RS08715	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
SHALO_RS08720	ENOG4105CSA	Coproporphyrinogen iii oxidase
SHALO_RS08725	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
SHALO_RS08730	ENOG4105KNI	merR family transcriptional Regulator
SHALO_RS08735	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
SHALO_RS08740	ENOG4105C0H	protease
SHALO_RS08765	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
SHALO_RS08775	ENOG4105BZU	Histidine kinase
SHALO_RS08780	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
SHALO_RS08785	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
SHALO_RS08795	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
SHALO_RS08800	ENOG4108512	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
SHALO_RS08805	ENOG4105VG0	50S ribosomal protein l34
SHALO_RS08820	ENOG4105DJI	Methylaspartate mutase, E subunit
SHALO_RS08835	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
SHALO_RS08850	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SHALO_RS08855	ENOG4105CN1	protease
SHALO_RS08865	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
SHALO_RS08870	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
SHALO_RS08880	ENOG4105E9Q	Acyl-transferase
SHALO_RS08885	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
SHALO_RS08895	ENOG4105C7Z	Conserved Protein
SHALO_RS08900	ENOG41085GJ	domain protein
SHALO_RS08940	ENOG4107QUV	Domain protein
SHALO_RS08960	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
SHALO_RS08980	ENOG4105DHT	Metal Dependent Phosphohydrolase
SHALO_RS08985	ENOG4105CGY	Dna recombination protein
SHALO_RS08995	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
SHALO_RS09005	ENOG4105EIN	peptidylprolyl cis-trans isomerase
SHALO_RS09010	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
SHALO_RS09015	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
SHALO_RS09030	ENOG4105D0M	Protease HtpX homolog
SHALO_RS09040	ENOG4105C5H	ABC transporter
SHALO_RS09045	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS09055	ENOG4105VG1	fes assembly suf system protein
SHALO_RS09070	ENOG4105DFH	Transport of potassium into the cell (By similarity)
SHALO_RS09075	ENOG4105DC1	bifunctional purine biosynthesis protein purh
SHALO_RS09080	ENOG4105KVY	Required for disulfide bond formation in some proteins (By similarity)
SHALO_RS09090	ENOG4108S4H	thioesterase Superfamily protein
SHALO_RS09095	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
SHALO_RS09100	ENOG4105C87	Aminotransferase class I and II
SHALO_RS09120	ENOG4108R5S	membrane
SHALO_RS09125	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
SHALO_RS09130	ENOG4105BZU	Histidine kinase
SHALO_RS09140	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
SHALO_RS09145	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
SHALO_RS09150	ENOG4105D5K	Hemolysin activator protein
SHALO_RS09155	ENOG4105CKT	filamentous hemagglutinin
SHALO_RS09155	ENOG4105CKT	filamentous hemagglutinin
SHALO_RS09220	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_RS09225	ENOG4105BZU	Histidine kinase
SHALO_RS09230	ENOG4105CY0	Metallo-Beta-Lactamase
SHALO_RS09235	ENOG4108IQE	Amp-dependent synthetase and ligase
SHALO_RS09245	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
SHALO_RS09250	ENOG4105C08	Histidine kinase
SHALO_RS09255	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
SHALO_RS09260	ENOG4105CZN	Potassium uptake protein
SHALO_RS09270	ENOG4105E0X	reductase
SHALO_RS09285	ENOG4105MFX	4-diphosphocytidyl-2c-methyl-d-erythritol synthase
SHALO_RS09290	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
SHALO_RS09295	ENOG4105DZS	Phenylacetate-CoA ligase
SHALO_RS09300	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
SHALO_RS09310	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
SHALO_RS09330	ENOG4105BZU	Histidine kinase
SHALO_RS09345	ENOG4105DS1	cytochrome b561
SHALO_RS09370	ENOG4105PGM	cation diffusion facilitator family transporter
SHALO_RS09390	ENOG4108ESX	Receptor
SHALO_RS09400	ENOG4105D64	Mechanosensitive ion channel
SHALO_RS09435	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
SHALO_RS09455	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
SHALO_RS09460	ENOG4108NIW	Leucine export protein LeuE
SHALO_RS09465	ENOG4108594	Permease of the drug metabolite transporter
SHALO_RS09475	ENOG4105BZU	Histidine kinase
SHALO_RS09480	ENOG4108YZA	Nitrogen regulatory protein pii
SHALO_RS09495	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_RS09520	ENOG4105NBK	UPF0345 protein
SHALO_RS09525	ENOG4105BZU	Histidine kinase
SHALO_RS09530	ENOG4105CBX	hi0933 family
SHALO_RS09540	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
SHALO_RS09545	ENOG4105CIY	formyltetrahydrofolate deformylase
SHALO_RS09565	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
SHALO_RS09570	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SHALO_RS09575	ENOG4105DKW	ABC transporter
SHALO_RS09600	ENOG4105CGK	Exodeoxyribonuclease III
SHALO_RS09620	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
SHALO_RS09625	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
SHALO_RS09635	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS09645	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
SHALO_RS09650	ENOG4108U5N	UPF0316 protein
SHALO_RS09660	ENOG4105BZU	Histidine kinase
SHALO_RS09675	ENOG4105C9U	ATP-dependent DNA helicase RecQ
SHALO_RS09690	ENOG4105C1J	atp-dependent rna helicase
SHALO_RS09700	ENOG4105BZU	Histidine kinase
SHALO_RS09740	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SHALO_RS09745	ENOG4105CR4	methylisocitrate lyase
SHALO_RS09750	ENOG4105BZN	citrate synthase
SHALO_RS09755	ENOG4105DXD	2-methylcitrate dehydratase
SHALO_RS09765	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
SHALO_RS09775	ENOG4108UMN	azlc family
SHALO_RS09780	ENOG4105CGA	flagellar basal-body rod protein FlgG
SHALO_RS09785	ENOG4105CGA	flagellar basal-body rod protein FlgG
SHALO_RS09790	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
SHALO_RS09800	ENOG4105KVH	Transcriptional regulator
SHALO_RS09820	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SHALO_RS09825	ENOG4107QN1	sodium solute
SHALO_RS09830	ENOG41062QD	Membrane
SHALO_RS09845	ENOG4105DWY	Agmatine deiminase
SHALO_RS09850	ENOG41076HS	cation diffusion facilitator family transporter
SHALO_RS09855	ENOG4105CE1	Ferrous iron transport protein b
SHALO_RS09860	ENOG4107K9B	ferrous iron transport protein
SHALO_RS09885	ENOG4105X1Q	TOBE domain protein
SHALO_RS09890	ENOG4107VIJ	nudix hydrolase
SHALO_RS09895	ENOG4105D7N	magnesium and cobalt transport protein CorA
SHALO_RS09900	ENOG4105DR5	peptidase
SHALO_RS09910	ENOG4105CQB	FAD linked oxidase domain protein
SHALO_RS09915	ENOG4107S2Z	UPF0761 membrane protein
SHALO_RS09930	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
SHALO_RS09935	ENOG4105C25	Primosomal protein n'
SHALO_RS09960	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
SHALO_RS09965	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
SHALO_RS09970	ENOG4108Z0R	Transferase
SHALO_RS09975	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
SHALO_RS09980	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
SHALO_RS09985	ENOG4105DJV	ribulose-phosphate 3-epimerase
SHALO_RS09990	ENOG4105VB9	50S ribosomal protein l28
SHALO_RS09995	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
SHALO_RS10010	ENOG4105D48	metallophosphoesterase
SHALO_RS10015	ENOG4108JA2	transcriptioN-repair coupling factor
SHALO_RS10025	ENOG4105DR5	peptidase
SHALO_RS10030	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
SHALO_RS10035	ENOG4105BZU	Histidine kinase
SHALO_RS10045	ENOG4105C8T	Leucyl-tRNA synthetase
SHALO_RS10050	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
SHALO_RS10055	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
SHALO_RS10060	ENOG4105VIE	preprotein translocase, subunit YajC
SHALO_RS10065	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
SHALO_RS10070	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
SHALO_RS10080	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
SHALO_RS10085	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
SHALO_RS10090	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
SHALO_RS10105	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
SHALO_RS10110	ENOG41085EF	Carbon storage regulator
SHALO_RS10115	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
SHALO_RS10120	ENOG4105C4R	Atp-dependent dna helicase
SHALO_RS10125	ENOG4105DUM	transcriptional regulator, lysR family
SHALO_RS10145	ENOG4105CRQ	synthase (Component I)
SHALO_RS10150	ENOG4105CXT	aspartate transcarbamylase
SHALO_RS10160	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
SHALO_RS10195	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
SHALO_RS10200	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
SHALO_RS10205	ENOG4105V3S	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
SHALO_RS10210	ENOG4105VB6	UPF0109 protein
SHALO_RS10220	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SHALO_RS10225	ENOG4105EI2	Pseudouridine synthase
SHALO_RS10230	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
SHALO_RS10240	ENOG4105EGD	dinuclear metal center protein, YbgI family
SHALO_RS10245	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
SHALO_RS10255	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
SHALO_RS10260	ENOG4105CFP	Peptidase U32
SHALO_RS10270	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
SHALO_RS10275	ENOG4105C5F	glutamine synthetase
SHALO_RS10280	ENOG4108JQC	penicillin-binding protein 1A
SHALO_RS10290	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
SHALO_RS10295	ENOG4107YJQ	MAF-like protein
SHALO_RS10305	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
SHALO_RS10320	ENOG4105BZU	Histidine kinase
SHALO_RS10325	ENOG4107QY8	reductase
SHALO_RS10330	ENOG4105QAX	Iron-sulfur
SHALO_RS10335	ENOG4107KGK	dmso reductase anchor subunit
SHALO_RS10340	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
SHALO_RS10355	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
SHALO_RS10365	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
SHALO_RS10380	ENOG4108ZC9	flagellar basal-body rod protein flgc
SHALO_RS10385	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
SHALO_RS10390	ENOG4105CNI	cell division protein FtsW
SHALO_RS10410	ENOG4105HKU	nucleoside recognition domain-containing protein
SHALO_RS10420	ENOG4108TVT	permease
SHALO_RS10460	ENOG4105DDQ	anthranilate synthase
SHALO_RS10465	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
SHALO_RS10475	ENOG41082BM	Transcriptional regulator, arsr family
SHALO_RS10495	ENOG4105CHY	citrate lyase, alpha
SHALO_RS10500	ENOG4105CI0	Citrate lyase
SHALO_RS10510	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
SHALO_RS10515	ENOG4108KK1	membrane protein AbrB duplication
SHALO_RS10525	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
SHALO_RS10530	ENOG4108MRH	transcriptional regulatory protein
SHALO_RS10550	ENOG4105BZU	Histidine kinase
SHALO_RS10555	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_RS10560	ENOG4105D94	Major Facilitator Superfamily
SHALO_RS10565	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
SHALO_RS10570	ENOG4105C7N	Xanthine uracil vitamin C permease
SHALO_RS10575	ENOG4105DVY	radical SAM domain protein
SHALO_RS10590	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
SHALO_RS10600	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
SHALO_RS10605	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
SHALO_RS10620	ENOG4105BZU	Histidine kinase
SHALO_RS10650	ENOG4105EYW	Ion transport protein
SHALO_RS10670	ENOG4105C5H	ABC transporter
SHALO_RS10675	ENOG4105BZU	Histidine kinase
SHALO_RS10680	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
SHALO_RS10700	ENOG4108JPZ	Monovalent cation H antiporter subunit D
SHALO_RS10705	ENOG4107TDF	Formate hydrogenlyase subunit 4
SHALO_RS10710	ENOG4107WQX	hydrogenase 4 membrane subunit
SHALO_RS10715	ENOG4108JPZ	Monovalent cation H antiporter subunit D
SHALO_RS10720	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
SHALO_RS10730	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
SHALO_RS10755	ENOG4105C22	threonyL-tRNA synthetase
SHALO_RS10765	ENOG4105CUZ	uba thif-type nad fad binding protein
SHALO_RS10785	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
SHALO_RS10790	ENOG4105D1F	ATP-binding protein
SHALO_RS10795	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
SHALO_RS10820	ENOG4108YYC	ycei family
SHALO_RS10825	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
SHALO_RS10830	ENOG4108PQF	modD protein
SHALO_RS10835	ENOG4105E0C	molybdate abc transporter
SHALO_RS10845	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SHALO_RS10850	ENOG4105E0C	molybdate abc transporter
SHALO_RS10860	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
SHALO_RS10865	ENOG4105F4R	Transcriptional regulator mode
SHALO_RS10870	ENOG4105DZ1	carboxypeptidase
SHALO_RS10875	ENOG4105II7	pyrroline-5-carboxylate reductase
SHALO_RS10880	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_RS10885	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_RS10890	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
SHALO_RS10895	ENOG4105DFG	type I secretion outer membrane protein
SHALO_RS10975	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
SHALO_RS10980	ENOG4105M7K	Involved in the transcription termination process (By similarity)
SHALO_RS10985	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
SHALO_RS11000	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
SHALO_RS11005	ENOG4105DJP	Membrane
SHALO_RS11010	ENOG4105D64	Mechanosensitive ion channel
SHALO_RS11015	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
SHALO_RS11020	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
SHALO_RS11030	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
SHALO_RS11040	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
SHALO_RS11045	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
SHALO_RS11055	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
SHALO_RS11060	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
SHALO_RS11065	ENOG4108VYJ	response regulator receiver protein
SHALO_RS11070	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
SHALO_RS11075	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
SHALO_RS11085	ENOG4107ZAZ	Oligosaccharyl transferase, STT3 subunit
SHALO_RS11090	ENOG4105C5E	polysaccharide biosynthesis protein
SHALO_RS11095	ENOG4105ESV	Glycosyl transferase, family 4
SHALO_RS11110	ENOG4108UW5	maltose o-acetyltransferase
SHALO_RS11125	ENOG4107XZA	Glycosyl transferase family 2
SHALO_RS11135	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SHALO_RS11140	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
SHALO_RS11145	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
SHALO_RS11150	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
SHALO_RS11160	ENOG4105C7K	acetolactate synthase
SHALO_RS11165	ENOG4105FAW	cDP-glucose 4,6-dehydratase
SHALO_RS11170	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
SHALO_RS11175	ENOG4105C30	Nad-dependent epimerase dehydratase
SHALO_RS11185	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
SHALO_RS11205	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
SHALO_RS11210	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
SHALO_RS11215	ENOG4107QKV	phosphomannomutase
SHALO_RS11265	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
SHALO_RS11270	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
SHALO_RS11275	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
SHALO_RS11295	ENOG4105C59	p-type ATPase
SHALO_RS11300	ENOG4105BZU	Histidine kinase
SHALO_RS11305	ENOG4105T38	integral membrane protein
SHALO_RS11310	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
SHALO_RS11315	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
SHALO_RS11325	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
SHALO_RS11330	ENOG4108R6K	riboflavin synthase, subunit alpha
SHALO_RS11335	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS11340	ENOG4107R7A	Allophanate hydrolase subunit 2
SHALO_RS11350	ENOG4105E7W	lamb ycsf family protein
SHALO_RS11355	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
SHALO_RS11370	ENOG4107YTP	response regulator receiver protein
SHALO_RS11380	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
SHALO_RS11385	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_RS11390	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SHALO_RS11405	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
SHALO_RS11410	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
SHALO_RS11415	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
SHALO_RS11420	ENOG4105CHR	reductase
SHALO_RS11425	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
SHALO_RS11435	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
SHALO_RS11445	ENOG4105D3Q	Sugar transferase
SHALO_RS11480	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
SHALO_RS11485	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
SHALO_RS11490	ENOG4105CMR	udp-glucose 4-epimerase
SHALO_RS11495	ENOG4105DB1	molybdopterin oxidoreductase
SHALO_RS11505	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_RS11515	ENOG4105ETX	regulatoR
SHALO_RS11520	ENOG4108KCW	iron-sulfur cluster binding
SHALO_RS11530	ENOG4108M8H	domain protein
SHALO_RS11550	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SHALO_RS11565	ENOG4105CJ3	phosphate transporter
SHALO_RS11570	ENOG4105C1J	atp-dependent rna helicase
SHALO_RS11575	ENOG4108UPT	UPF0178 protein
SHALO_RS11600	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
SHALO_RS11605	ENOG4107R4J	Chloride channel
SHALO_RS11615	ENOG4107QW4	alcohol dehydrogenase
SHALO_RS11630	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
SHALO_RS11645	ENOG4105CDV	Ompa motb domain protein
SHALO_RS11660	ENOG4107XGZ	Hydrolase
SHALO_RS11665	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
SHALO_RS11670	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
SHALO_RS11695	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
SHALO_RS11700	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
SHALO_RS11705	ENOG4108ZPB	UPF0306 protein
SHALO_RS11720	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
SHALO_RS11725	ENOG4105BZS	acriflavin resistance protein
SHALO_RS11740	ENOG4105C57	major facilitator superfamily
SHALO_RS11785	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
SHALO_RS11790	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
SHALO_RS11800	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
SHALO_RS11805	ENOG4105KVH	Transcriptional regulator
SHALO_RS11820	ENOG4105NAU	thioesterase Superfamily protein
SHALO_RS11825	ENOG4105BZU	Histidine kinase
SHALO_RS11830	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_RS11850	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS11855	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
SHALO_RS11860	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS11865	ENOG4105PWN	phosphate abc transporter
SHALO_RS11870	ENOG4105C8U	phosphate abc transporter
SHALO_RS11880	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
SHALO_RS11895	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS11915	ENOG4107EFR	Flavocytochrome c
SHALO_RS11930	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
SHALO_RS11935	ENOG4108UJD	30S ribosomal protein S9
SHALO_RS11940	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
SHALO_RS11985	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
SHALO_RS11990	ENOG4108PYU	two-component system response regulator
SHALO_RS12005	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
SHALO_RS12025	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
SHALO_RS12030	ENOG4105CYE	ATP phosphoribosyltransferase regulatory subunit
SHALO_RS12035	ENOG4107UUH	Aminotransferase
SHALO_RS12040	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS12045	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS12050	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
SHALO_RS12055	ENOG4105CV1	Transketolase (EC 2.2.1.1)
SHALO_RS12070	ENOG41084FT	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
SHALO_RS12075	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
SHALO_RS12080	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
SHALO_RS12095	ENOG4108ZT0	50S ribosomal protein l17
SHALO_RS12100	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
SHALO_RS12110	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
SHALO_RS12115	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SHALO_RS12120	ENOG41067V7	50S ribosomal protein L36
SHALO_RS12125	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
SHALO_RS12130	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
SHALO_RS12135	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
SHALO_RS12140	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
SHALO_RS12145	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
SHALO_RS12150	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
SHALO_RS12165	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
SHALO_RS12170	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SHALO_RS12180	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
SHALO_RS12185	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
SHALO_RS12190	ENOG41084HJ	50s ribosomal protein l29
SHALO_RS12200	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
SHALO_RS12205	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
SHALO_RS12210	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
SHALO_RS12225	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
SHALO_RS12230	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
SHALO_RS12250	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SHALO_RS12255	ENOG4107SJW	iron permease, FTR1
SHALO_RS12280	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_RS12300	ENOG4105CE1	Ferrous iron transport protein b
SHALO_RS12305	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
SHALO_RS12310	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
SHALO_RS12315	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
SHALO_RS12325	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
SHALO_RS12330	ENOG4105CDH	Citrulline--aspartate ligase
SHALO_RS12345	ENOG4105BZU	Histidine kinase
SHALO_RS12350	ENOG4108UNF	response regulator
SHALO_RS12355	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
SHALO_RS12360	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
SHALO_RS12365	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
SHALO_RS12370	ENOG4105E0F	Histidine kinase
SHALO_RS12375	ENOG4105BZU	Histidine kinase
SHALO_RS12380	ENOG4105CBS	Chea signal transduction histidine kinase
SHALO_RS12390	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS12395	ENOG4108V3W	Chemotaxis protein, CheW
SHALO_RS12425	ENOG4105CGH	5'-nucleotidase
SHALO_RS12435	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
SHALO_RS12480	ENOG4107QIV	Cytochrome c biogenesis protein
SHALO_RS12545	ENOG4105PV3	Inner membrane protein yqiJ
SHALO_RS12550	ENOG4107S78	Band 7 protein
SHALO_RS12620	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
SHALO_RS12625	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SHALO_RS12635	ENOG4105CE1	Ferrous iron transport protein b
SHALO_RS12640	ENOG4105XFK	Ferrous iron transport protein A
SHALO_RS12650	ENOG4105CNM	Receptor
SHALO_RS12665	ENOG4105E93	esterase
SHALO_RS12670	ENOG4108ESX	Receptor
SHALO_RS12680	ENOG4105M15	transport protein ExbD
SHALO_RS12685	ENOG4105M8K	biopolymer transport protein
SHALO_RS12690	ENOG4105PGM	cation diffusion facilitator family transporter
SHALO_RS12695	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
SHALO_RS12710	ENOG4105BZ1	(ABC) transporter
SHALO_RS12720	ENOG4107ZSV	Receptor
SHALO_RS12725	ENOG4107ZSV	Receptor
SHALO_RS12730	ENOG4105UEI	Transcriptional Regulator AraC Family
SHALO_RS12740	ENOG4105BZU	Histidine kinase
SHALO_RS12765	ENOG4105D5T	phosphonate abc transporter
SHALO_RS12780	ENOG4105PAD	Hydrolase
SHALO_RS12785	ENOG4105KK4	UPF0060 membrane protein
SHALO_RS12795	ENOG4105D7X	high-affinity nickel-transporter
SHALO_RS12800	ENOG4105D7X	high-affinity nickel-transporter
SHALO_RS12810	ENOG4108TGK	Low-potential electron donor to a number of redox enzymes (By similarity)
SHALO_RS12820	ENOG4105N14	lysine exporter protein LysE YggA
SHALO_RS12825	ENOG4105ECP	epimerase
SHALO_RS12840	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_RS12855	ENOG410829K	Lysine exporter protein (Lyse ygga)
SHALO_RS12865	ENOG4105BZU	Histidine kinase
SHALO_RS12870	ENOG4105FR1	rard protein
SHALO_RS12880	ENOG4105DHQ	Histidine kinase
SHALO_RS12885	ENOG4105DIJ	Phosphoethanolamine transferase
SHALO_RS12895	ENOG4107XTP	(EAL) domain protein
SHALO_RS12925	ENOG4107SDU	Methyl-accepting chemotaxis
SHALO_RS12935	ENOG4105VYW	UPF0251 protein
SHALO_RS12940	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
SHALO_RS12945	ENOG4105CXK	mandelate racemase muconate lactonizing
SHALO_RS12950	ENOG4105D01	(LipO)protein
SHALO_RS12965	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
SHALO_RS12970	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
SHALO_RS13015	ENOG4105RQ9	TPR repeat-containing protein
SHALO_RS13035	ENOG4105S10	periplasmic binding protein
SHALO_RS13040	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
SHALO_RS13050	ENOG4108IJ0	Aspartate ammonia-lyase
SHALO_RS13055	ENOG4108IJ0	Aspartate ammonia-lyase
SHALO_RS13060	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
SHALO_RS13065	ENOG4105HDK	L-asparaginase
SHALO_RS13075	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
SHALO_RS13085	ENOG4105EAB	amino acid AbC transporter
SHALO_RS13090	ENOG4105E5Q	amino acid AbC transporter
SHALO_RS13100	ENOG4107R3N	Filamentation induced by cAMP protein fic
SHALO_RS13140	ENOG4105CRE	cytochrome C
SHALO_RS13145	ENOG4105DVI	reductase, NrfD
SHALO_RS13150	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_RS13155	ENOG4108V1T	peptidylprolyl cis-trans isomerase
SHALO_RS13160	ENOG4105V2T	cytochrome C
SHALO_RS13170	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
SHALO_RS13175	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS13185	ENOG4105KVH	Transcriptional regulator
SHALO_RS13190	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
SHALO_RS13195	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
SHALO_RS13220	ENOG4105M15	transport protein ExbD
SHALO_RS13225	ENOG4105M8K	biopolymer transport protein
SHALO_RS13230	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
SHALO_RS13235	ENOG4105VFE	sira family
SHALO_RS13245	ENOG4106TNF	Periplasmic binding protein
SHALO_RS13255	ENOG4105BZU	Histidine kinase
SHALO_RS13265	ENOG4105DXB	Major Facilitator superfamily
SHALO_RS13290	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
SHALO_RS13295	ENOG4105C8W	ABC transporter
SHALO_RS13305	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
SHALO_RS13315	ENOG4105QAX	Iron-sulfur
SHALO_RS13345	ENOG4105E0A	ABC, transporter
SHALO_RS13350	ENOG4105EHG	Permease protein
SHALO_RS13355	ENOG4105S10	periplasmic binding protein
SHALO_RS13375	ENOG4105M15	transport protein ExbD
SHALO_RS13380	ENOG4105M8K	biopolymer transport protein
SHALO_RS13385	ENOG4105F4R	Transcriptional regulator mode
SHALO_RS13400	ENOG4105S10	periplasmic binding protein
SHALO_RS13410	ENOG4108BSC	Methyltransferase
SHALO_RS13420	ENOG4105WMR	Protein CrcB homolog
SHALO_RS13445	ENOG4105ID8	Transcriptional regulator, ARAC family
SHALO_RS13455	ENOG4105QAX	Iron-sulfur
SHALO_RS13495	ENOG4105BZU	Histidine kinase
SHALO_RS13500	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
SHALO_RS13505	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
SHALO_RS13510	ENOG4105EM7	Selenocysteine-specific translation elongation factor
SHALO_RS13515	ENOG41086B8	CoB-CoM heterodisulfide reductase
SHALO_RS13520	ENOG4105E33	succinate dehydrogenase
SHALO_RS13525	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
SHALO_RS13535	ENOG4105GVJ	transcriptional regulator
SHALO_RS13545	ENOG4105C2I	pirin domain protein
SHALO_RS13615	ENOG4105C84	Histidine ammonia-lyase
SHALO_RS13620	ENOG4105CHR	reductase
SHALO_RS13640	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
SHALO_RS13680	ENOG4105C1J	atp-dependent rna helicase
SHALO_RS13695	ENOG410829K	Lysine exporter protein (Lyse ygga)
SHALO_RS13715	ENOG4108KS2	transglutaminase domain protein
SHALO_RS13725	ENOG4105DVP	Adenine-specific
SHALO_RS13730	ENOG4108VYJ	response regulator receiver protein
SHALO_RS13745	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SHALO_RS13755	ENOG4105EIG	urea carboxylase-associated protein 1
SHALO_RS13760	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SHALO_RS13765	ENOG4108UMI	ABC transporter, permease
SHALO_RS13805	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
SHALO_RS13810	ENOG4105C08	Histidine kinase
SHALO_RS13815	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
SHALO_RS13820	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
SHALO_RS13825	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
SHALO_RS13830	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
SHALO_RS13840	ENOG4108NVR	Methyl-accepting chemotaxis
SHALO_RS13845	ENOG4105E1F	short-chain dehydrogenase reductase
SHALO_RS13860	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
SHALO_RS13865	ENOG4105CA3	membrane-bound lytic murein transglycosylase
SHALO_RS13870	ENOG4107RDB	Major Facilitator
SHALO_RS13875	ENOG4105W39	Membrane
SHALO_RS13895	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
SHALO_RS13900	ENOG4108ZEX	molybdopterin converting factor, subunit 2
SHALO_RS13910	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
SHALO_RS13915	ENOG4105C3J	Cysteine desulfurase
SHALO_RS13920	ENOG4108JIR	Flagellum-specific ATP synthase
SHALO_RS13925	ENOG4105EUJ	GTP cyclohydrolase i
SHALO_RS13935	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
SHALO_RS13950	ENOG4105C0P	Mg chelatase subunit ChlI
SHALO_RS13955	ENOG4108ENG	carbohydrate kinase, YjeF related protein
SHALO_RS13965	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
SHALO_RS14020	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
SHALO_RS14030	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_RS14035	ENOG4107QY8	reductase
SHALO_RS14070	ENOG4105C26	Dehydrogenase
SHALO_RS14085	ENOG4108JQ1	Dehydrogenase
SHALO_RS14105	ENOG41061MD	high-affinity nickel-transporter
SHALO_RS14125	ENOG4108DBC	nitroreductase
SHALO_RS14135	ENOG4107QPK	)-transporter
SHALO_RS14140	ENOG4108M3J	Dehydrogenase
SHALO_RS14150	ENOG4107QWP	ABC-2 type transporter
SHALO_RS14155	ENOG4107QWP	ABC-2 type transporter
SHALO_RS14160	ENOG4105CJ1	ABC, transporter
SHALO_RS14165	ENOG4105D0S	secretion protein (HlyD
SHALO_RS14170	ENOG4107MVR	Transcriptional regulator
SHALO_RS14205	ENOG4107EFR	Flavocytochrome c
SHALO_RS14230	ENOG4108HYG	acetyltransferase
SHALO_RS14235	ENOG4108YYH	Nadph-dependent fmn reductase
SHALO_RS14245	ENOG4108IJF	Heavy metal efflux pump, CzcA
SHALO_RS14250	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
SHALO_RS14285	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
SHALO_RS14290	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
SHALO_RS14300	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
SHALO_RS14310	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
SHALO_RS14315	ENOG4105C11	sulfate adenylyltransferase), subunit 2
SHALO_RS14320	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
SHALO_RS14330	ENOG4105D06	uba thif-type nad fad binding protein
SHALO_RS14340	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
SHALO_RS14345	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
SHALO_RS14350	ENOG4108IQK	o-acetylhomoserine
SHALO_RS14360	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
SHALO_RS14380	ENOG4105GR3	Histidine kinase
SHALO_RS14390	ENOG4105BZU	Histidine kinase
SHALO_RS14415	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
SHALO_RS14420	ENOG4108UXE	Protein tyrosine phosphatase
SHALO_RS14425	ENOG4107R5R	arsenical pump membrane protein
SHALO_RS14430	ENOG4108UXE	Protein tyrosine phosphatase
SHALO_RS14440	ENOG4108K28	Arsenite oxidase, large subunit
SHALO_RS14455	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
SHALO_RS14460	ENOG4105C19	ABC transporter
SHALO_RS14470	ENOG4105BZU	Histidine kinase
SHALO_RS14485	ENOG4105C3J	Cysteine desulfurase
SHALO_RS14490	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_RS14495	ENOG4105CVA	phosphate
SHALO_RS14500	ENOG4105C8Q	Methyl-accepting chemotaxis
SHALO_RS14510	ENOG4105EE5	Membrane protein terC
SHALO_RS14515	ENOG4108XUR	Pfam:DUF178
SHALO_RS14520	ENOG4105D82	Glutamate dehydrogenase
SHALO_RS14525	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
SHALO_RS14530	ENOG4105C6K	Malic enzyme
SHALO_RS14535	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
SHALO_RS14545	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
SHALO_RS14550	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
SHALO_RS14555	ENOG4105DHP	deoxycytidine triphosphate deaminase
SHALO_RS14570	ENOG4105DR4	Methyltransferase
SHALO_RS14585	ENOG4105I03	Flagellin
SHALO_RS14590	ENOG4105C5E	polysaccharide biosynthesis protein
SHALO_RS14595	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
SHALO_RS14600	ENOG4105F0R	Cytidylyltransferase
SHALO_RS14605	ENOG4107DKY	pseudaminic acid biosynthesis-associated protein PseG
SHALO_RS14635	ENOG4105CAQ	asparagine synthetase
SHALO_RS14655	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
SHALO_RS14675	ENOG4105CAQ	asparagine synthetase
SHALO_RS14680	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
SHALO_RS14705	ENOG4105I03	Flagellin
SHALO_RS14710	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
SHALO_RS14715	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
SHALO_RS14720	ENOG4105BZN	citrate synthase
SHALO_RS14735	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
SHALO_RS14740	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
SHALO_RS14745	ENOG4105E63	Pfam:DUF178
SHALO_RS14755	ENOG4105D4A	Cell wall formation (By similarity)
SHALO_RS14760	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
SHALO_RS14770	ENOG4105BZU	Histidine kinase
SHALO_RS14790	ENOG4105DIN	metallophosphoesterase
SHALO_RS14795	ENOG4105BZG	amino acid carrier protein
SHALO_RS14800	ENOG4105C2W	permease
SHALO_RS14805	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
SHALO_RS14810	ENOG4105KNE	Phosphatidate cytidylyltransferase
SHALO_RS14825	ENOG4105BZW	Glycerate kinase
SHALO_RS14830	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
SHALO_RS14850	ENOG4105CH6	catalase
SHALO_RS14855	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
SHALO_RS14865	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
SHALO_RS14870	ENOG41080AZ	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
SHALO_RS14895	ENOG4105HDD	phospholipase
SHALO_RS14900	ENOG4105VFU	Rna-binding protein
SHALO_RS14905	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
SHALO_RS14960	ENOG4105KHC	sulfurtransferase
SHALO_RS14970	ENOG4105D1F	ATP-binding protein
SHALO_RS15015	ENOG4105HFZ	Membrane
SHALO_RS15030	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_RS15035	ENOG4108J2R	molybdopterin oxidoreductase
SHALO_RS15045	ENOG4105DUM	transcriptional regulator, lysR family
SHALO_RS15065	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
SHALO_RS15070	ENOG4107QY8	reductase
SHALO_RS15075	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
SHALO_RS15080	ENOG4105F8J	Adenylate Guanylate cyclase
SHALO_RS15085	ENOG4105DHT	Metal Dependent Phosphohydrolase
SHALO_RS15090	ENOG4105NU9	Preprotein translocase subunit SecG
SHALO_RS15100	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
SHALO_RS15105	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
SHALO_RS15130	ENOG4108V0P	LemA family
SHALO_RS15135	ENOG4105CI3	gtp-binding protein typa
SHALO_RS15150	ENOG4108JQA	flagellar
SHALO_RS15155	ENOG4105BZE	flagellar hook protein, FlgE
SHALO_RS15170	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
SHALO_RS15175	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
SHALO_RS15205	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
SHALO_RS15345	ENOG4105C8Q	Methyl-accepting chemotaxis