locus-tag	class	description
FA592_RS00125	COG0745	RESPONSE REGULATOR receiver
FA592_RS00135	COG0437	4 iron, 4 sulfur cluster binding
FA592_RS00145	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FA592_RS00155	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
FA592_RS00165	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FA592_RS00175	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FA592_RS00195	COG1120	ATPase activity
FA592_RS00210	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FA592_RS00255	COG1132	(ABC) transporter
FA592_RS00260	COG1797	cobyrinic acid a,c-diamide synthase activity
FA592_RS00270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FA592_RS00270	COG1648	precorrin-2 dehydrogenase activity
FA592_RS00275	COG1309	transcriptional regulator
FA592_RS00360	COG0582	viral genome integration into host DNA
FA592_RS00370	COG0776	regulation of translation
FA592_RS00380	COG1674	ftsk spoiiie
FA592_RS00380	COG1196	nuclear chromosome segregation
FA592_RS00385	COG1049	propionate catabolic process, 2-methylcitrate cycle
FA592_RS00390	COG1047	Peptidyl-prolyl cis-trans
FA592_RS00395	COG0574	Belongs to the PEP-utilizing enzyme family
FA592_RS00395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FA592_RS00400	COG3713	MltA-interacting MipA family protein
FA592_RS00410	COG2814	Major facilitator Superfamily
FA592_RS00430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FA592_RS00435	COG0840	transmembrane signaling receptor activity
FA592_RS00440	COG1832	CoA-binding protein
FA592_RS00445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FA592_RS00455	COG1126	abc transporter atp-binding protein
FA592_RS00460	COG0765	amino acid transport
FA592_RS00465	COG4597	amino acid ABC transporter
FA592_RS00470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA592_RS00475	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FA592_RS00490	COG0586	Pfam SNARE associated Golgi protein
FA592_RS00495	COG0577	efflux transmembrane transporter activity
FA592_RS00495	COG1136	(ABC) transporter
FA592_RS00500	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FA592_RS00505	COG0492	ferredoxin-NADP+ reductase activity
FA592_RS00520	COG0727	PFAM Uncharacterised protein family (UPF0153)
FA592_RS00530	COG0134	indole-3-glycerol-phosphate synthase activity
FA592_RS00540	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FA592_RS00545	COG1122	ATPase activity
FA592_RS00560	COG0310	cobalt ion transport
FA592_RS00565	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FA592_RS00570	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FA592_RS00585	COG0446	pyridine nucleotide-disulphide oxidoreductase
FA592_RS00600	COG0028	Belongs to the TPP enzyme family
FA592_RS00605	COG0440	acetolactate synthase activity
FA592_RS00610	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FA592_RS00620	COG0493	'glutamate synthase
FA592_RS00630	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FA592_RS00660	COG1045	serine acetyltransferase
FA592_RS00665	COG1166	arginine decarboxylase activity
FA592_RS00670	COG0124	histidyl-tRNA synthetase
FA592_RS00685	COG0163	prenyltransferase activity
FA592_RS00700	COG0840	transmembrane signaling receptor activity
FA592_RS00705	COG0303	'Molybdopterin
FA592_RS00710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FA592_RS00725	COG1691	(AIR) carboxylase
FA592_RS00730	COG1606	tRNA processing
FA592_RS00735	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FA592_RS00740	COG3875	lactate racemase activity
FA592_RS00745	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FA592_RS00745	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FA592_RS00760	COG0784	Response regulator, receiver
FA592_RS00760	COG2205	protein histidine kinase activity
FA592_RS00765	COG0745	RESPONSE REGULATOR receiver
FA592_RS00780	COG0588	phosphoglycerate mutase activity
FA592_RS00790	COG0582	viral genome integration into host DNA
FA592_RS00795	COG0343	queuine tRNA-ribosyltransferase activity
FA592_RS00805	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FA592_RS00815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FA592_RS00820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FA592_RS00840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA592_RS00845	COG1187	pseudouridine synthase activity
FA592_RS00855	COG0028	Belongs to the TPP enzyme family
FA592_RS00885	COG1309	transcriptional regulator
FA592_RS00920	COG3290	protein histidine kinase activity
FA592_RS00920	COG0840	transmembrane signaling receptor activity
FA592_RS00925	COG1592	Rubrerythrin
FA592_RS00935	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FA592_RS00945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FA592_RS00945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FA592_RS00950	COG3030	protein affecting phage T7 exclusion by the F plasmid
FA592_RS00955	COG0442	prolyl-tRNA aminoacylation
FA592_RS00960	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FA592_RS00965	COG0142	geranyltranstransferase activity
FA592_RS00985	COG1959	2 iron, 2 sulfur cluster binding
FA592_RS00995	COG3706	GGDEF domain
FA592_RS01000	COG0525	valine-tRNA ligase activity
FA592_RS01005	COG0521	Mo-molybdopterin cofactor biosynthetic process
FA592_RS01010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FA592_RS01015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FA592_RS01030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FA592_RS01035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FA592_RS01045	COG2195	Cleaves the N-terminal amino acid of tripeptides
FA592_RS01055	COG0500	methyltransferase
FA592_RS01070	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FA592_RS01075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FA592_RS01080	COG1663	tetraacyldisaccharide 4'-kinase activity
FA592_RS01085	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FA592_RS01090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FA592_RS01095	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FA592_RS01105	COG4232	protein-disulfide reductase activity
FA592_RS01115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FA592_RS01120	COG0443	Heat shock 70 kDa protein
FA592_RS01125	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FA592_RS01130	COG1420	regulation of RNA biosynthetic process
FA592_RS01145	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FA592_RS01150	COG1959	2 iron, 2 sulfur cluster binding
FA592_RS01155	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FA592_RS01160	COG2404	hydrolase activity, acting on ester bonds
FA592_RS01170	COG2226	methyltransferase
FA592_RS01175	COG2199	diguanylate cyclase activity
FA592_RS01175	COG2203	Gaf domain
FA592_RS01180	COG0196	riboflavin kinase activity
FA592_RS01190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FA592_RS01195	COG0730	response to heat
FA592_RS01205	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FA592_RS01220	COG0527	aspartate kinase activity
FA592_RS01225	COG0494	nUDIX hydrolase
FA592_RS01230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FA592_RS01240	COG0789	Transcriptional regulator
FA592_RS01245	COG0484	heat shock protein binding
FA592_RS01255	COG0745	RESPONSE REGULATOR receiver
FA592_RS01260	COG0642	Histidine kinase
FA592_RS01275	COG0653	protein targeting
FA592_RS01280	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FA592_RS01290	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FA592_RS01295	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FA592_RS01305	COG0706	membrane insertase activity
FA592_RS01310	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FA592_RS01315	COG0594	ribonuclease P activity
FA592_RS01320	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FA592_RS01350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FA592_RS01365	COG0542	response to heat
FA592_RS01370	COG0793	Belongs to the peptidase S41A family
FA592_RS01375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FA592_RS01380	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FA592_RS01385	COG0047	phosphoribosylformylglycinamidine synthase activity
FA592_RS01395	COG0204	Acyl-transferase
FA592_RS01400	COG0326	Molecular chaperone. Has ATPase activity
FA592_RS01420	COG1331	Highly conserved protein containing a thioredoxin domain
FA592_RS01460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FA592_RS01480	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FA592_RS01490	COG2608	mercury ion transmembrane transporter activity
FA592_RS01495	COG2217	Heavy metal translocating P-type atpase
FA592_RS01500	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FA592_RS01515	COG0275	rRNA processing
FA592_RS01525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FA592_RS01530	COG0849	cell division
FA592_RS01535	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FA592_RS01545	COG2890	protein-(glutamine-N5) methyltransferase activity
FA592_RS01545	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FA592_RS01550	COG0501	Belongs to the peptidase M48B family
FA592_RS01565	COG0840	transmembrane signaling receptor activity
FA592_RS01575	COG2151	metal-sulfur cluster biosynthetic enzyme
FA592_RS01590	COG0138	bifunctional purine biosynthesis protein purh
FA592_RS01595	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FA592_RS01605	COG1607	acyl-coa hydrolase
FA592_RS01610	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FA592_RS01615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FA592_RS01640	COG0842	Transport permease protein
FA592_RS01645	COG0842	Transport permease protein
FA592_RS01650	COG1131	(ABC) transporter
FA592_RS01655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA592_RS01660	COG1309	transcriptional regulator
FA592_RS01670	COG3328	transposase activity
FA592_RS01675	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FA592_RS01685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FA592_RS01690	COG0805	protein transport
FA592_RS01695	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FA592_RS01720	COG3437	response regulator, receiver
FA592_RS01725	COG4999	Histidine kinase
FA592_RS01725	COG2205	protein histidine kinase activity
FA592_RS01725	COG3437	response regulator, receiver
FA592_RS01725	COG3850	Histidine kinase
FA592_RS01730	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FA592_RS01755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FA592_RS01760	COG0569	domain protein
FA592_RS01765	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FA592_RS01780	COG2068	MobA-Related Protein
FA592_RS01785	COG3608	succinylglutamate desuccinylase aspartoacylase
FA592_RS01785	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FA592_RS01790	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FA592_RS01805	COG2226	methyltransferase
FA592_RS01825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA592_RS01825	COG2198	Histidine kinase
FA592_RS01825	COG2205	protein histidine kinase activity
FA592_RS01825	COG0784	Response regulator, receiver
FA592_RS01855	COG0646	methionine synthase
FA592_RS01855	COG1410	methionine synthase
FA592_RS01870	COG0840	transmembrane signaling receptor activity
FA592_RS01875	COG1280	lysine exporter protein (LysE YggA)
FA592_RS01895	COG0004	ammonium transporteR
FA592_RS01900	COG0347	Belongs to the P(II) protein family
FA592_RS01920	COG0751	glycine-tRNA ligase activity
FA592_RS01935	COG0288	reversible hydration of carbon dioxide
FA592_RS01940	COG3123	guanosine phosphorylase activity
FA592_RS01950	COG2081	HI0933 family
FA592_RS01960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FA592_RS01965	COG0788	formyltetrahydrofolate deformylase activity
FA592_RS01985	COG0473	3-isopropylmalate dehydrogenase activity
FA592_RS01990	COG0066	3-isopropylmalate dehydratase activity
FA592_RS02025	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FA592_RS02040	COG0708	Exodeoxyribonuclease III
FA592_RS02055	COG0840	transmembrane signaling receptor activity
FA592_RS02060	COG2816	NAD+ diphosphatase activity
FA592_RS02065	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FA592_RS02070	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FA592_RS02075	COG4319	ketosteroid isomerase
FA592_RS02090	COG0840	transmembrane signaling receptor activity
FA592_RS02100	COG4977	sequence-specific DNA binding
FA592_RS02110	COG0431	NADPH-dependent FMN reductase
FA592_RS02115	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FA592_RS02120	COG3706	GGDEF domain
FA592_RS02130	COG4895	conserved protein (DUF2196)
FA592_RS02150	COG0513	Belongs to the DEAD box helicase family
FA592_RS02160	COG0642	Histidine kinase
FA592_RS02165	COG0745	RESPONSE REGULATOR receiver
FA592_RS02200	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FA592_RS02205	COG0372	Belongs to the citrate synthase family
FA592_RS02210	COG2079	MmgE PrpD family protein
FA592_RS02220	COG2824	Alkylphosphonate utilization operon protein PhnA
FA592_RS02230	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FA592_RS02245	COG4786	Flagellar basal body rod
FA592_RS02250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FA592_RS02260	COG1733	regulation of RNA biosynthetic process
FA592_RS02275	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FA592_RS02280	COG1121	(ABC) transporter
FA592_RS02285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FA592_RS02305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FA592_RS02310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FA592_RS02315	COG3162	membrane
FA592_RS02320	COG0745	RESPONSE REGULATOR receiver
FA592_RS02325	COG0642	Histidine kinase
FA592_RS02340	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FA592_RS02345	COG1918	ferrous iron import across plasma membrane
FA592_RS02370	COG3585	molybdate ion transport
FA592_RS02380	COG0598	Magnesium transport protein CorA
FA592_RS02385	COG0739	heme binding
FA592_RS02395	COG0277	FAD linked oxidase domain protein
FA592_RS02400	COG1295	ribonuclease BN
FA592_RS02410	COG0305	Participates in initiation and elongation during chromosome replication
FA592_RS02415	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FA592_RS02420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FA592_RS02450	COG0556	nucleotide-excision repair
FA592_RS02460	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FA592_RS02465	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FA592_RS02470	COG2176	DNA-directed DNA polymerase activity
FA592_RS02475	COG0135	phosphoribosylanthranilate isomerase activity
FA592_RS02480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FA592_RS02490	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FA592_RS02505	COG1692	metallophosphoesterase
FA592_RS02510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FA592_RS02520	COG0739	heme binding
FA592_RS02525	COG0285	dihydrofolate synthase activity
FA592_RS02530	COG3706	GGDEF domain
FA592_RS02540	COG0495	leucyl-tRNA aminoacylation
FA592_RS02545	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FA592_RS02550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FA592_RS02555	COG1862	Preprotein translocase
FA592_RS02560	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FA592_RS02565	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FA592_RS02575	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FA592_RS02585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FA592_RS02595	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FA592_RS02600	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FA592_RS02605	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FA592_RS02610	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FA592_RS02615	COG0210	DNA helicase
FA592_RS02655	COG0540	Belongs to the ATCase OTCase family
FA592_RS02665	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FA592_RS02705	COG0228	four-way junction DNA binding
FA592_RS02710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FA592_RS02715	COG0564	pseudouridine synthase activity
FA592_RS02720	COG1519	Transferase
FA592_RS02730	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FA592_RS02735	COG0752	glycyl-tRNA synthetase alpha subunit
FA592_RS02745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FA592_RS02760	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FA592_RS02765	COG0174	glutamine synthetase
FA592_RS02775	COG4172	Belongs to the ABC transporter superfamily
FA592_RS02780	COG0156	8-amino-7-oxononanoate synthase activity
FA592_RS02785	COG0424	maF-like protein
FA592_RS02795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FA592_RS02820	COG1028	Short-chain dehydrogenase reductase Sdr
FA592_RS02830	COG0673	inositol 2-dehydrogenase activity
FA592_RS02835	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FA592_RS02840	COG0768	penicillin binding
FA592_RS02850	COG1558	bacterial-type flagellum-dependent cell motility
FA592_RS02855	COG1815	bacterial-type flagellum-dependent cell motility
FA592_RS02860	COG0772	Belongs to the SEDS family
FA592_RS02865	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FA592_RS02900	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FA592_RS02910	COG0697	spore germination
FA592_RS02950	COG0512	Glutamine amidotransferase of anthranilate synthase
FA592_RS02965	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FA592_RS02975	COG1518	maintenance of DNA repeat elements
FA592_RS03105	COG0330	HflC and HflK could
FA592_RS03140	COG2814	Major facilitator Superfamily
FA592_RS03150	COG0640	Transcriptional regulator
FA592_RS03170	COG2301	Belongs to the HpcH HpaI aldolase family
FA592_RS03175	COG3052	prosthetic group binding
FA592_RS03190	COG2814	Major facilitator Superfamily
FA592_RS03200	COG2252	PERMEase
FA592_RS03205	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FA592_RS03215	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FA592_RS03225	COG0133	tryptophan synthase activity
FA592_RS03235	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FA592_RS03240	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FA592_RS03245	COG3706	GGDEF domain
FA592_RS03265	COG2199	diguanylate cyclase activity
FA592_RS03265	COG2200	EAL domain
FA592_RS03265	COG2202	Pas domain
FA592_RS03275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FA592_RS03295	COG0488	(ABC) transporter
FA592_RS03300	COG2207	Transcriptional regulator
FA592_RS03300	COG4753	response regulator
FA592_RS03315	COG1151	hydroxylamine reductase activity
FA592_RS03325	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_RS03335	COG0650	Formate hydrogenlyase subunit 4
FA592_RS03340	COG4237	Hydrogenase 4 membrane
FA592_RS03345	COG0651	ATP synthesis coupled electron transport
FA592_RS03350	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FA592_RS03350	COG3261	NADH dehydrogenase
FA592_RS03360	COG3260	NADH ubiquinone oxidoreductase 20
FA592_RS03395	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FA592_RS03410	COG2171	N-acyltransferase activity
FA592_RS03415	COG0489	protein tyrosine kinase activity
FA592_RS03420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FA592_RS03420	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FA592_RS03430	COG2046	Belongs to the sulfate adenylyltransferase family
FA592_RS03440	COG2353	YceI-like domain
FA592_RS03445	COG1739	Uncharacterized protein family UPF0029
FA592_RS03450	COG0157	Belongs to the NadC ModD family
FA592_RS03465	COG3842	ATPase activity
FA592_RS03490	COG1686	Belongs to the peptidase S11 family
FA592_RS03495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FA592_RS03500	COG1136	(ABC) transporter
FA592_RS03500	COG0577	efflux transmembrane transporter activity
FA592_RS03505	COG1136	(ABC) transporter
FA592_RS03525	COG0668	transmembrane transport
FA592_RS03530	COG3300	MHYT domain
FA592_RS03530	COG5001	Diguanylate cyclase
FA592_RS03545	COG3645	SOS response
FA592_RS03665	COG0284	orotidine-5'-phosphate decarboxylase activity
FA592_RS03670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FA592_RS03675	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FA592_RS03685	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FA592_RS03690	COG0697	spore germination
FA592_RS03695	COG0668	transmembrane transport
FA592_RS03700	COG1160	GTP binding
FA592_RS03715	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FA592_RS03725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FA592_RS03730	COG1183	phosphatidylcholine synthase activity
FA592_RS03740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FA592_RS03745	COG2264	protein methyltransferase activity
FA592_RS03750	COG0745	RESPONSE REGULATOR receiver
FA592_RS03755	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FA592_RS03760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FA592_RS03775	COG1086	Polysaccharide biosynthesis protein
FA592_RS03780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FA592_RS03795	COG1442	glycosyl transferase family 8
FA592_RS03795	COG1216	Glycosyl transferase, family 2
FA592_RS03805	COG0110	maltose O-acetyltransferase activity
FA592_RS03830	COG0028	Belongs to the TPP enzyme family
FA592_RS03840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FA592_RS03855	COG1793	dna ligase
FA592_RS03865	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FA592_RS03870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FA592_RS03895	COG0859	PFAM glycosyl transferase family 9
FA592_RS03905	COG1215	transferase activity, transferring glycosyl groups
FA592_RS03920	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FA592_RS03925	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FA592_RS03925	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FA592_RS03930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FA592_RS03960	COG5001	Diguanylate cyclase
FA592_RS03960	COG5002	protein histidine kinase activity
FA592_RS03965	COG0697	spore germination
FA592_RS03975	COG3706	GGDEF domain
FA592_RS04000	COG0840	transmembrane signaling receptor activity
FA592_RS04005	COG1984	allophanate hydrolase subunit 2
FA592_RS04015	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FA592_RS04020	COG0445	tRNA wobble uridine modification
FA592_RS04025	COG0723	plastoquinol--plastocyanin reductase activity
FA592_RS04030	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FA592_RS04035	COG2857	Cytochrome c1
FA592_RS04045	COG0825	malonyl-CoA metabolic process
FA592_RS04050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FA592_RS04055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FA592_RS04065	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FA592_RS04070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FA592_RS04075	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FA592_RS04100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FA592_RS04105	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FA592_RS04120	COG0463	Glycosyl transferase, family 2
FA592_RS04135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FA592_RS04140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FA592_RS04165	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FA592_RS04200	COG0662	Cupin 2, conserved barrel domain protein
FA592_RS04200	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FA592_RS04205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FA592_RS04230	COG0745	RESPONSE REGULATOR receiver
FA592_RS04245	COG0398	Pfam SNARE associated Golgi protein
FA592_RS04250	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FA592_RS04265	COG0390	transport system, permease component
FA592_RS04270	COG0439	Biotin carboxylase
FA592_RS04285	COG0513	Belongs to the DEAD box helicase family
FA592_RS04290	COG1671	Belongs to the UPF0178 family
FA592_RS04295	COG0667	Aldo Keto reductase
FA592_RS04300	COG2814	Major facilitator Superfamily
FA592_RS04305	COG2207	Transcriptional regulator
FA592_RS04325	COG0573	inorganic phosphate transmembrane transporter activity
FA592_RS04335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FA592_RS04345	COG3384	dioxygenase
FA592_RS04365	COG0745	RESPONSE REGULATOR receiver
FA592_RS04375	COG1607	acyl-coa hydrolase
FA592_RS04395	COG1733	regulation of RNA biosynthetic process
FA592_RS04400	COG2249	NAD(P)H dehydrogenase (quinone) activity
FA592_RS04405	COG3852	Histidine kinase
FA592_RS04410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FA592_RS04415	COG0602	queuosine metabolic process
FA592_RS04450	COG1702	phosphate starvation-inducible protein PhoH
FA592_RS04460	COG2814	Major facilitator Superfamily
FA592_RS04465	COG0477	Major facilitator Superfamily
FA592_RS04475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA592_RS04495	COG3787	Belongs to the UPF0306 family
FA592_RS04500	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FA592_RS04530	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FA592_RS04530	COG0674	pyruvate-flavodoxin oxidoreductase activity
FA592_RS04530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_RS04530	COG1013	pyruvate-flavodoxin oxidoreductase activity
FA592_RS04540	COG0471	metal ion transport
FA592_RS04555	COG3047	cAMP biosynthetic process
FA592_RS04555	COG2885	chlorophyll binding
FA592_RS04570	COG2207	Transcriptional regulator
FA592_RS04575	COG0519	Catalyzes the synthesis of GMP from XMP
FA592_RS04595	COG1979	alcohol dehydrogenase
FA592_RS04610	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FA592_RS04625	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FA592_RS04630	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FA592_RS04635	COG1074	ATP-dependent DNA helicase activity
FA592_RS04675	COG3278	Belongs to the heme-copper respiratory oxidase family
FA592_RS04680	COG0745	RESPONSE REGULATOR receiver
FA592_RS04695	COG0505	Belongs to the CarA family
FA592_RS04715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FA592_RS04720	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FA592_RS04725	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FA592_RS04735	COG0840	transmembrane signaling receptor activity
FA592_RS04740	COG0546	phosphoglycolate phosphatase activity
FA592_RS04755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FA592_RS04760	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FA592_RS04765	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FA592_RS04770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FA592_RS04785	COG0203	ribosomal protein L17
FA592_RS04795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FA592_RS04800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FA592_RS04805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FA592_RS04810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FA592_RS04820	COG0024	Methionine aminopeptidase
FA592_RS04825	COG0201	protein transport
FA592_RS04830	COG0200	Binds to the 23S rRNA
FA592_RS04835	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FA592_RS04840	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FA592_RS04845	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FA592_RS04850	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FA592_RS04855	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FA592_RS04865	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FA592_RS04870	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FA592_RS04875	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FA592_RS04880	COG0255	Belongs to the universal ribosomal protein uL29 family
FA592_RS04885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FA592_RS04890	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FA592_RS04900	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FA592_RS04905	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FA592_RS04910	COG0089	rRNA binding
FA592_RS04915	COG0088	Forms part of the polypeptide exit tunnel
FA592_RS04920	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FA592_RS04925	COG0051	transcription antitermination factor activity, RNA binding
FA592_RS04940	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FA592_RS04945	COG0672	)-iron permease
FA592_RS04970	COG0577	efflux transmembrane transporter activity
FA592_RS04970	COG1136	(ABC) transporter
FA592_RS04990	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FA592_RS04995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FA592_RS05000	COG0571	ribonuclease III activity
FA592_RS05005	COG0328	RNA-DNA hybrid ribonuclease activity
FA592_RS05015	COG0358	DNA primase activity
FA592_RS05020	COG0137	argininosuccinate synthase activity
FA592_RS05025	COG2201	protein-glutamate methylesterase activity
FA592_RS05045	COG2205	protein histidine kinase activity
FA592_RS05050	COG2201	protein-glutamate methylesterase activity
FA592_RS05055	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FA592_RS05090	COG0643	Histidine kinase
FA592_RS05090	COG2198	Histidine kinase
FA592_RS05100	COG0840	transmembrane signaling receptor activity
FA592_RS05105	COG0835	chemotaxis
FA592_RS05110	COG0745	RESPONSE REGULATOR receiver
FA592_RS05115	COG0484	heat shock protein binding
FA592_RS05140	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FA592_RS05145	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FA592_RS05165	COG1280	lysine exporter protein (LysE YggA)
FA592_RS05170	COG1090	epimerase
FA592_RS05220	COG2962	Rard protein
FA592_RS05230	COG3850	Histidine kinase
FA592_RS05230	COG5002	protein histidine kinase activity
FA592_RS05235	COG2194	sulfuric ester hydrolase activity
FA592_RS05245	COG2200	EAL domain
FA592_RS05260	COG1968	undecaprenyl-diphosphatase activity
FA592_RS05265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FA592_RS05270	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FA592_RS05295	COG1027	Aspartate ammonia-lyase
FA592_RS05310	COG0252	asparaginase activity
FA592_RS05315	COG4191	Histidine kinase
FA592_RS05320	COG0745	RESPONSE REGULATOR receiver
FA592_RS05325	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FA592_RS05335	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FA592_RS05340	COG0804	urea catabolic process
FA592_RS05345	COG0832	Belongs to the urease beta subunit family
FA592_RS05345	COG0831	urea catabolic process
FA592_RS05350	COG0829	nickel cation binding
FA592_RS05380	COG0784	Response regulator, receiver
FA592_RS05380	COG2205	protein histidine kinase activity
FA592_RS05385	COG0745	RESPONSE REGULATOR receiver
FA592_RS05400	COG0714	Associated with various cellular activities
FA592_RS05445	COG0765	amino acid transport
FA592_RS05480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FA592_RS05485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FA592_RS05520	COG0709	Synthesizes selenophosphate from selenide and ATP
FA592_RS05525	COG0425	Belongs to the sulfur carrier protein TusA family
FA592_RS05535	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FA592_RS05540	COG3447	MASE1 domain protein
FA592_RS05540	COG5001	Diguanylate cyclase
FA592_RS05540	COG5002	protein histidine kinase activity
FA592_RS05550	COG2814	Major facilitator Superfamily
FA592_RS05575	COG3839	Belongs to the ABC transporter superfamily
FA592_RS05580	COG4662	Binding-protein-dependent transport system inner membrane component
FA592_RS05585	COG2998	abc-type tungstate transport system, permease component
FA592_RS05595	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FA592_RS05605	COG0437	4 iron, 4 sulfur cluster binding
FA592_RS05630	COG1120	ATPase activity
FA592_RS05645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FA592_RS05660	COG0848	biopolymer transport protein
FA592_RS05665	COG0811	peptide transport
FA592_RS05690	COG0500	methyltransferase
FA592_RS05700	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FA592_RS05705	COG4208	sulfate ABC transporter
FA592_RS05710	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FA592_RS05715	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FA592_RS05720	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FA592_RS05760	COG0437	4 iron, 4 sulfur cluster binding
FA592_RS05790	COG2205	protein histidine kinase activity
FA592_RS05800	COG1921	L-seryl-tRNASec selenium transferase activity
FA592_RS05825	COG1741	Belongs to the pirin family
FA592_RS05860	COG0745	RESPONSE REGULATOR receiver
FA592_RS05865	COG0642	Histidine kinase
FA592_RS05875	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FA592_RS05880	COG0463	Glycosyl transferase, family 2
FA592_RS05890	COG1028	Short-chain dehydrogenase reductase Sdr
FA592_RS05945	COG0513	Belongs to the DEAD box helicase family
FA592_RS05975	COG1305	Transglutaminase-like
FA592_RS05990	COG0745	RESPONSE REGULATOR receiver
FA592_RS06010	COG0439	Biotin carboxylase
FA592_RS06025	COG1116	anion transmembrane transporter activity
FA592_RS06030	COG2011	ABC-type metal ion transport system permease component
FA592_RS06040	COG0642	Histidine kinase
FA592_RS06045	COG0745	RESPONSE REGULATOR receiver
FA592_RS06080	COG0300	oxidoreductase activity
FA592_RS06095	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FA592_RS06105	COG2814	Major facilitator Superfamily
FA592_RS06110	COG1238	metal cluster binding
FA592_RS06125	COG0471	metal ion transport
FA592_RS06140	COG0303	'Molybdopterin
FA592_RS06145	COG0314	molybdopterin synthase activity
FA592_RS06165	COG1157	protein secretion by the type III secretion system
FA592_RS06170	COG0302	gtp cyclohydrolase
FA592_RS06175	COG0544	peptidyl-prolyl cis-trans isomerase activity
FA592_RS06180	COG0740	serine-type endopeptidase activity
FA592_RS06195	COG0606	chelatase, subunit chli
FA592_RS06200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FA592_RS06200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FA592_RS06210	COG2022	thiamine diphosphate biosynthetic process
FA592_RS06240	COG0582	viral genome integration into host DNA
FA592_RS06325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA592_RS06330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA592_RS06345	COG0463	Glycosyl transferase, family 2
FA592_RS06360	COG0671	phosphoesterase, PA-phosphatase related
FA592_RS06375	COG1012	belongs to the aldehyde dehydrogenase family
FA592_RS06390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FA592_RS06415	COG0840	transmembrane signaling receptor activity
FA592_RS06420	COG2183	response to ionizing radiation
FA592_RS06440	COG0842	Transport permease protein
FA592_RS06445	COG0842	Transport permease protein
FA592_RS06450	COG1131	(ABC) transporter
FA592_RS06455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA592_RS06465	COG0778	Nitroreductase
FA592_RS06510	COG0577	efflux transmembrane transporter activity
FA592_RS06515	COG1136	(ABC) transporter
FA592_RS06525	COG1472	Belongs to the glycosyl hydrolase 3 family
FA592_RS06555	COG0431	NADPH-dependent FMN reductase
FA592_RS06565	COG0300	oxidoreductase activity
FA592_RS06575	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA592_RS06580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA592_RS06620	COG0745	RESPONSE REGULATOR receiver
FA592_RS06625	COG0642	Histidine kinase
FA592_RS06635	COG0175	sulfate reduction
FA592_RS06640	COG0175	sulfate reduction
FA592_RS06645	COG2895	sulfate adenylyltransferase (ATP) activity
FA592_RS06655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FA592_RS06665	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FA592_RS06670	COG1648	precorrin-2 dehydrogenase activity
FA592_RS06670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FA592_RS06675	COG0626	cystathionine gamma-synthase activity
FA592_RS06685	COG0482	sulfurtransferase activity
FA592_RS06705	COG3706	GGDEF domain
FA592_RS06715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FA592_RS06725	COG0861	Integral membrane protein TerC family
FA592_RS06730	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FA592_RS06735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FA592_RS06740	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FA592_RS06745	COG0281	malic enzyme
FA592_RS06745	COG0280	phosphate acetyltransferase
FA592_RS06750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FA592_RS06760	COG0439	Biotin carboxylase
FA592_RS06765	COG0511	ligase activity, forming carbon-carbon bonds
FA592_RS06770	COG0717	Belongs to the dCTP deaminase family
FA592_RS06790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FA592_RS06795	COG1073	alpha beta
FA592_RS06810	COG1086	Polysaccharide biosynthesis protein
FA592_RS06815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FA592_RS06820	COG1083	cytidylyl-transferase
FA592_RS06830	COG2226	methyltransferase
FA592_RS06835	COG2089	acid synthase
FA592_RS06840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FA592_RS06870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FA592_RS06875	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FA592_RS06880	COG0372	Belongs to the citrate synthase family
FA592_RS06895	COG0148	phosphopyruvate hydratase activity
FA592_RS06900	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FA592_RS06905	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FA592_RS06915	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FA592_RS06925	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FA592_RS06955	COG1408	metallophosphoesterase
FA592_RS06960	COG1115	amino acid carrier protein
FA592_RS06965	COG2233	PERMEase
FA592_RS06970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FA592_RS06975	COG0575	Belongs to the CDS family
FA592_RS07010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FA592_RS07020	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FA592_RS07025	COG0746	molybdenum cofactor guanylyltransferase activity
FA592_RS07060	COG0315	cyclic pyranopterin monophosphate synthase activity
FA592_RS07065	COG2921	Belongs to the UPF0250 family
FA592_RS07125	COG0670	Belongs to the BI1 family
FA592_RS07140	COG0437	4 iron, 4 sulfur cluster binding
FA592_RS07145	COG0243	molybdopterin cofactor binding
FA592_RS07150	COG4106	trans-aconitate 2-methyltransferase activity
FA592_RS07170	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FA592_RS07175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FA592_RS07185	COG0233	cytoplasmic translational termination
FA592_RS07190	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FA592_RS07215	COG1704	LemA family
FA592_RS07230	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FA592_RS07235	COG1749	Flagellar hook protein flgE
FA592_RS07240	COG1749	Flagellar hook protein flgE
FA592_RS07245	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FA592_RS07250	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FA592_RS07260	COG0592	DNA-directed DNA polymerase activity
FA592_RS07290	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FA592_RS07295	COG1194	a g-specific adenine glycosylase
FA592_RS07300	COG2814	Major facilitator Superfamily
FA592_RS07315	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FA592_RS07355	COG0840	transmembrane signaling receptor activity
FA592_RS07375	COG1335	isochorismatase
FA592_RS07395	COG3708	Transcriptional regulator
FA592_RS07395	COG2207	Transcriptional regulator
FA592_RS07405	COG1355	regulation of microtubule-based process
FA592_RS07415	COG2078	PFAM AMMECR1 domain protein
FA592_RS07450	COG3150	esterase
FA592_RS07460	COG3383	formate dehydrogenase (NAD+) activity
FA592_RS07490	COG0129	dihydroxy-acid dehydratase activity
FA592_RS07495	COG2095	MarC family integral membrane protein
FA592_RS07520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FA592_RS07525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FA592_RS07530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FA592_RS07545	COG1328	CTP reductase activity
FA592_RS07545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FA592_RS07550	COG1794	racemase activity, acting on amino acids and derivatives
FA592_RS07555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FA592_RS07560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FA592_RS07565	COG0564	pseudouridine synthase activity
FA592_RS07570	COG0179	Fumarylacetoacetate (FAA) hydrolase
FA592_RS07575	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FA592_RS07585	COG0107	imidazoleglycerol-phosphate synthase activity
FA592_RS07595	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FA592_RS07600	COG0517	IMP dehydrogenase activity
FA592_RS07600	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FA592_RS07605	COG1187	pseudouridine synthase activity
FA592_RS07630	COG2257	FlhB HrpN YscU SpaS Family
FA592_RS07650	COG0237	dephospho-CoA kinase activity
FA592_RS07655	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FA592_RS07665	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FA592_RS07670	COG0268	Binds directly to 16S ribosomal RNA
FA592_RS07675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FA592_RS07680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FA592_RS07690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FA592_RS07695	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FA592_RS07700	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FA592_RS07705	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FA592_RS07710	COG0348	domain, Protein
FA592_RS07720	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FA592_RS07735	COG0754	glutathionylspermidine amidase activity
FA592_RS07740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FA592_RS07755	COG2194	sulfuric ester hydrolase activity
FA592_RS07800	COG0642	Histidine kinase
FA592_RS07805	COG0745	RESPONSE REGULATOR receiver
FA592_RS07825	COG1127	ABC transporter
FA592_RS07830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FA592_RS07845	COG2095	MarC family integral membrane protein
FA592_RS07850	COG0840	transmembrane signaling receptor activity
FA592_RS07860	COG3437	response regulator, receiver
FA592_RS07860	COG0784	Response regulator, receiver
FA592_RS07870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FA592_RS07880	COG5002	protein histidine kinase activity
FA592_RS07890	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FA592_RS07900	COG0004	ammonium transporteR
FA592_RS07905	COG0667	Aldo Keto reductase
FA592_RS07915	COG0745	RESPONSE REGULATOR receiver
FA592_RS07930	COG0765	amino acid transport
FA592_RS07970	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FA592_RS07980	COG0318	PFAM AMP-dependent synthetase and ligase
FA592_RS07985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FA592_RS07990	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_RS07995	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_RS08000	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_RS08005	COG0649	NAD binding
FA592_RS08025	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FA592_RS08030	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_RS08035	COG0839	Belongs to the complex I subunit 6 family
FA592_RS08040	COG0713	ATP synthesis coupled electron transport
FA592_RS08045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FA592_RS08065	COG1012	belongs to the aldehyde dehydrogenase family
FA592_RS08075	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FA592_RS08090	COG0840	transmembrane signaling receptor activity
FA592_RS08095	COG0840	transmembrane signaling receptor activity
FA592_RS08115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FA592_RS08120	COG0254	rRNA binding
FA592_RS08125	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FA592_RS08130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FA592_RS08145	COG0436	Aminotransferase
FA592_RS08150	COG0460	homoserine dehydrogenase
FA592_RS08155	COG0792	nuclease activity
FA592_RS08160	COG3118	belongs to the thioredoxin family
FA592_RS08165	COG0492	ferredoxin-NADP+ reductase activity
FA592_RS08170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FA592_RS08175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FA592_RS08180	COG1242	4 iron, 4 sulfur cluster binding
FA592_RS08195	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FA592_RS08195	COG0140	phosphoribosyl-ATP diphosphatase activity
FA592_RS08210	COG1012	belongs to the aldehyde dehydrogenase family
FA592_RS08215	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FA592_RS08230	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FA592_RS08235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FA592_RS08240	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FA592_RS08245	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FA592_RS08260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FA592_RS08280	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FA592_RS08285	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FA592_RS08290	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FA592_RS08295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FA592_RS08300	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FA592_RS08310	COG0784	Response regulator, receiver
FA592_RS08310	COG0835	chemotaxis
FA592_RS08315	COG2198	Histidine kinase
FA592_RS08315	COG0784	Response regulator, receiver
FA592_RS08315	COG0643	Histidine kinase
FA592_RS08320	COG0835	chemotaxis
FA592_RS08335	COG0560	Phosphoserine phosphatase
FA592_RS08355	COG0193	aminoacyl-tRNA hydrolase activity
FA592_RS08365	COG0019	diaminopimelate decarboxylase activity
FA592_RS08370	COG0077	Prephenate dehydratase
FA592_RS08370	COG1605	Chorismate mutase
FA592_RS08375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FA592_RS08385	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FA592_RS08395	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FA592_RS08400	COG0735	belongs to the Fur family
FA592_RS08405	COG0450	alkyl hydroperoxide reductase
FA592_RS08410	COG0840	transmembrane signaling receptor activity
FA592_RS08420	COG0105	UTP biosynthetic process
FA592_RS08430	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FA592_RS08435	COG0416	fatty acid biosynthetic process
FA592_RS08440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FA592_RS08445	COG0714	Associated with various cellular activities
FA592_RS08465	COG2304	oxidoreductase activity
FA592_RS08480	COG0287	Prephenate dehydrogenase
FA592_RS08485	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FA592_RS08495	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_RS08505	COG0745	RESPONSE REGULATOR receiver
FA592_RS08515	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FA592_RS08525	COG0157	Belongs to the NadC ModD family
FA592_RS08530	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FA592_RS08545	COG0850	regulation of cytokinetic process
FA592_RS08550	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FA592_RS08570	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FA592_RS08580	COG0779	Required for maturation of 30S ribosomal subunits
FA592_RS08585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FA592_RS08585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FA592_RS08600	COG5001	Diguanylate cyclase
FA592_RS08610	COG5002	protein histidine kinase activity
FA592_RS08640	COG3258	Cytochrome c
FA592_RS08650	COG1242	4 iron, 4 sulfur cluster binding
FA592_RS08655	COG0243	molybdopterin cofactor binding
FA592_RS08660	COG0437	4 iron, 4 sulfur cluster binding
FA592_RS08665	COG3301	Polysulphide reductase, NrfD
FA592_RS08670	COG2199	diguanylate cyclase activity
FA592_RS08670	COG2200	EAL domain
FA592_RS08670	COG3287	FIST C domain
FA592_RS08680	COG0437	4 iron, 4 sulfur cluster binding
FA592_RS08685	COG3301	Polysulphide reductase, NrfD
FA592_RS08690	COG0745	RESPONSE REGULATOR receiver
FA592_RS08705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FA592_RS08730	COG0848	biopolymer transport protein
FA592_RS08735	COG0811	peptide transport
FA592_RS08740	COG1227	inorganic diphosphatase activity
FA592_RS08760	COG1570	exodeoxyribonuclease VII activity
FA592_RS08775	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FA592_RS08795	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FA592_RS08805	COG2207	Transcriptional regulator
FA592_RS08810	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FA592_RS08815	COG0583	DNA-binding transcription factor activity
FA592_RS08820	COG2855	membrane
FA592_RS08825	COG0386	Belongs to the glutathione peroxidase family
FA592_RS08830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FA592_RS08840	COG0402	S-adenosylhomocysteine deaminase activity
FA592_RS08845	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FA592_RS08850	COG0006	proline dipeptidase activity
FA592_RS08855	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FA592_RS08860	COG1419	protein localization to endoplasmic reticulum
FA592_RS08865	COG0455	bacterial-type flagellum organization
FA592_RS08875	COG1191	sigma factor activity
FA592_RS08880	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FA592_RS08885	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FA592_RS08885	COG1776	CheC inhibitor of MCP methylation
FA592_RS08900	COG0463	Glycosyl transferase, family 2
FA592_RS08910	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FA592_RS08930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FA592_RS08940	COG1040	competence protein
FA592_RS08975	COG2204	response regulator
FA592_RS08980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FA592_RS08990	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FA592_RS08995	COG0731	radical SAM domain protein
FA592_RS09005	COG2358	TRAP transporter, solute receptor (TAXI family
FA592_RS09015	COG0582	viral genome integration into host DNA
FA592_RS09070	COG1464	Belongs to the NlpA lipoprotein family
FA592_RS09075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FA592_RS09080	COG2011	ABC-type metal ion transport system permease component
FA592_RS09085	COG0306	phosphate transporter
FA592_RS09090	COG0039	L-malate dehydrogenase activity
FA592_RS09095	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FA592_RS09140	COG2199	diguanylate cyclase activity
FA592_RS09140	COG2200	EAL domain
FA592_RS09140	COG3287	FIST C domain
FA592_RS09160	COG3118	belongs to the thioredoxin family
FA592_RS09170	COG4336	lyase activity
FA592_RS09195	COG4628	conserved protein (DUF2132)
FA592_RS09200	COG4221	oxidoreductase activity
FA592_RS09235	COG3022	response to hydroperoxide
FA592_RS09260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FA592_RS09265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FA592_RS09280	COG0250	Participates in transcription elongation, termination and antitermination
FA592_RS09285	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FA592_RS09290	COG0081	regulation of translation
FA592_RS09295	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FA592_RS09300	COG0222	ribosome binding
FA592_RS09305	COG0085	RNA polymerase activity
FA592_RS09310	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FA592_RS09315	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FA592_RS09325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FA592_RS09335	COG0697	spore germination
FA592_RS09340	COG0656	L-ascorbic acid biosynthetic process
FA592_RS09350	COG0471	metal ion transport
FA592_RS09355	COG0534	Mate efflux family protein
FA592_RS09370	COG0745	RESPONSE REGULATOR receiver
FA592_RS09375	COG0747	negative chemotaxis
FA592_RS09385	COG0840	transmembrane signaling receptor activity
FA592_RS09390	COG0840	transmembrane signaling receptor activity
FA592_RS09400	COG1034	ATP synthesis coupled electron transport
FA592_RS09405	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FA592_RS09410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_RS09415	COG0839	Belongs to the complex I subunit 6 family
FA592_RS09420	COG0713	ATP synthesis coupled electron transport
FA592_RS09425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FA592_RS09430	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_RS09435	COG1007	ATP synthesis coupled electron transport
FA592_RS09460	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FA592_RS09465	COG0649	NAD binding
FA592_RS09465	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_RS09470	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_RS09475	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_RS09490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FA592_RS09510	COG0357	Ribosomal RNA small subunit methyltransferase G
FA592_RS09525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FA592_RS09530	COG1970	mechanosensitive ion channel activity
FA592_RS09540	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FA592_RS09545	COG0113	porphobilinogen synthase activity
FA592_RS09550	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FA592_RS09560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FA592_RS09565	COG0247	lactate metabolic process
FA592_RS09580	COG3012	SEC-C Motif Domain Protein
FA592_RS09595	COG3706	GGDEF domain
FA592_RS09600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FA592_RS09610	COG1053	succinate dehydrogenase
FA592_RS09615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FA592_RS09625	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FA592_RS09635	COG0628	permease
FA592_RS09640	COG2255	four-way junction helicase activity
FA592_RS09645	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FA592_RS09655	COG0159	tryptophan synthase activity
FA592_RS09675	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FA592_RS09680	COG1136	(ABC) transporter
FA592_RS09685	COG1684	flagellar biosynthetic protein fliR
FA592_RS09695	COG0194	GDP metabolic process
FA592_RS09700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FA592_RS09705	COG0018	arginyl-trna synthetase
FA592_RS09715	COG2199	diguanylate cyclase activity
FA592_RS09715	COG3287	FIST C domain
FA592_RS09715	COG2200	EAL domain
FA592_RS09765	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FA592_RS09775	COG0149	triose-phosphate isomerase activity
FA592_RS09780	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FA592_RS09795	COG0195	Participates in both transcription termination and antitermination
FA592_RS09830	COG0037	tRNA processing
FA592_RS09835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FA592_RS09840	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FA592_RS09845	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FA592_RS09870	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FA592_RS09875	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FA592_RS09880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FA592_RS09910	COG2326	polyphosphate kinase activity
FA592_RS09925	COG0723	plastoquinol--plastocyanin reductase activity
FA592_RS09930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FA592_RS09945	COG0513	Belongs to the DEAD box helicase family
FA592_RS09950	COG1944	ATP diphosphatase activity
FA592_RS09970	COG2204	response regulator
FA592_RS09975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FA592_RS10005	COG0411	ABC transporter
FA592_RS10015	COG1333	cytochrome c biogenesis protein
FA592_RS10015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FA592_RS10055	COG1058	Belongs to the CinA family
FA592_RS10055	COG1546	Belongs to the CinA family
FA592_RS10060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FA592_RS10075	COG0516	GMP reductase activity
FA592_RS10075	COG0517	IMP dehydrogenase activity
FA592_RS10080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FA592_RS10095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FA592_RS10100	COG0436	Aminotransferase
FA592_RS10115	COG1193	negative regulation of DNA recombination
FA592_RS10120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FA592_RS10125	COG0251	oxidation-reduction process
FA592_RS10130	COG0579	oxidoreductase
FA592_RS10150	COG0793	Belongs to the peptidase S41A family
FA592_RS10150	COG3409	Peptidoglycan-binding domain 1 protein
FA592_RS10165	COG0469	pyruvate kinase activity
FA592_RS10170	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FA592_RS10175	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FA592_RS10180	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FA592_RS10185	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FA592_RS10190	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FA592_RS10200	COG1192	Involved in chromosome partitioning
FA592_RS10205	COG1475	DNA binding
FA592_RS10215	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FA592_RS10220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FA592_RS10230	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FA592_RS10245	COG0811	peptide transport
FA592_RS10250	COG0848	biopolymer transport protein
FA592_RS10260	COG0823	Involved in the tonB-independent uptake of proteins
FA592_RS10275	COG1047	Peptidyl-prolyl cis-trans
FA592_RS10285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FA592_RS10290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FA592_RS10295	COG0037	tRNA processing
FA592_RS10305	COG0067	glutamate synthase
FA592_RS10305	COG0069	glutamate synthase activity
FA592_RS10305	COG0070	glutamate synthase
FA592_RS10310	COG0493	'glutamate synthase
FA592_RS10320	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FA592_RS10325	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FA592_RS10330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FA592_RS10340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FA592_RS10360	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FA592_RS10360	COG1776	CheC inhibitor of MCP methylation
FA592_RS10410	COG0748	coenzyme F420 binding
FA592_RS10425	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FA592_RS10430	COG1028	Short-chain dehydrogenase reductase Sdr
FA592_RS10435	COG1846	Transcriptional regulator
FA592_RS10450	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FA592_RS10460	COG1113	amino acid transport
FA592_RS10465	COG0730	response to heat
FA592_RS10470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FA592_RS10475	COG1301	dicarboxylic acid transport
FA592_RS10480	COG1301	dicarboxylic acid transport
FA592_RS10490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FA592_RS10490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FA592_RS10495	COG1971	Probably functions as a manganese efflux pump
FA592_RS10515	COG0484	heat shock protein binding
FA592_RS10525	COG0745	RESPONSE REGULATOR receiver
FA592_RS10530	COG0642	Histidine kinase
FA592_RS10535	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FA592_RS10545	COG0840	transmembrane signaling receptor activity
FA592_RS10550	COG0318	PFAM AMP-dependent synthetase and ligase
FA592_RS10555	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FA592_RS10560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FA592_RS10575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FA592_RS10580	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FA592_RS10595	COG3706	GGDEF domain
FA592_RS10605	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FA592_RS10625	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FA592_RS10640	COG0784	Response regulator, receiver
FA592_RS10640	COG2205	protein histidine kinase activity
FA592_RS10640	COG5002	protein histidine kinase activity
FA592_RS10655	COG0322	excinuclease ABC activity
FA592_RS10665	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FA592_RS10675	COG0519	Catalyzes the synthesis of GMP from XMP
FA592_RS10675	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FA592_RS10695	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FA592_RS10705	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FA592_RS10720	COG0511	ligase activity, forming carbon-carbon bonds
FA592_RS10725	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FA592_RS10730	COG0165	Argininosuccinate lyase
FA592_RS10735	COG0537	adenosine 5'-monophosphoramidase activity
FA592_RS10740	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FA592_RS10745	COG0072	phenylalanine-tRNA ligase activity
FA592_RS10745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA592_RS10750	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FA592_RS10755	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FA592_RS10760	COG1185	polyribonucleotide nucleotidyltransferase activity
FA592_RS10760	COG0539	negative regulation of cytoplasmic translation
FA592_RS10770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FA592_RS10780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA592_RS10790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FA592_RS10805	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FA592_RS10830	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FA592_RS10840	COG2996	Protein conserved in bacteria
FA592_RS10845	COG2081	HI0933 family
FA592_RS10870	COG1902	pentaerythritol trinitrate reductase activity
FA592_RS10875	COG1538	Outer membrane efflux protein
FA592_RS10900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA592_RS10905	COG0840	transmembrane signaling receptor activity
FA592_RS10910	COG0840	transmembrane signaling receptor activity
FA592_RS10920	COG0587	DNA-directed DNA polymerase activity
FA592_RS10925	COG0642	Histidine kinase
FA592_RS10935	COG1346	cytolysis
FA592_RS10940	COG1380	Effector of murein hydrolase LrgA
FA592_RS10960	COG0772	Belongs to the SEDS family
FA592_RS10965	COG0564	pseudouridine synthase activity
FA592_RS10975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FA592_RS10980	COG1136	(ABC) transporter
FA592_RS10995	COG0528	UMP kinase activity
FA592_RS11000	COG1758	RNA polymerase activity
FA592_RS11005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FA592_RS11010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FA592_RS11015	COG2070	2-Nitropropane dioxygenase
FA592_RS11020	COG0860	N-Acetylmuramoyl-L-alanine amidase
FA592_RS11030	COG0563	adenylate kinase activity
FA592_RS11035	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FA592_RS11040	COG3706	GGDEF domain
FA592_RS11050	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FA592_RS11055	COG0497	DNA recombination
FA592_RS11065	COG0084	hydrolase, TatD family'
FA592_RS11070	COG1388	LysM domain
FA592_RS11070	COG3942	CHAP domain
FA592_RS11075	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FA592_RS11080	COG0131	Imidazoleglycerol-phosphate dehydratase
FA592_RS11085	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FA592_RS11100	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FA592_RS11140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA592_RS11140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FA592_RS11150	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FA592_RS11175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FA592_RS11180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FA592_RS11220	COG3005	denitrification pathway
FA592_RS11230	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FA592_RS11230	COG1333	cytochrome c biogenesis protein
FA592_RS11250	COG3545	Serine hydrolase
FA592_RS11260	COG0463	Glycosyl transferase, family 2
FA592_RS11275	COG0398	Pfam SNARE associated Golgi protein
FA592_RS11285	COG0398	Pfam SNARE associated Golgi protein
FA592_RS11295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FA592_RS11305	COG0697	spore germination
FA592_RS11340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FA592_RS11350	COG0243	molybdopterin cofactor binding
FA592_RS11355	COG0437	4 iron, 4 sulfur cluster binding
FA592_RS11360	COG0348	domain, Protein
FA592_RS11365	COG3043	anaerobic respiration
FA592_RS11370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_RS11370	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_RS11420	COG1271	oxidase subunit
FA592_RS11425	COG1294	oxidase, subunit
FA592_RS11450	COG0243	molybdopterin cofactor binding
FA592_RS11455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_RS11465	COG0745	RESPONSE REGULATOR receiver
FA592_RS11480	COG2863	cytochrome
FA592_RS11485	COG0723	plastoquinol--plastocyanin reductase activity
FA592_RS11490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FA592_RS11505	COG2199	diguanylate cyclase activity
FA592_RS11505	COG3287	FIST C domain
FA592_RS11505	COG2200	EAL domain
FA592_RS11515	COG0513	Belongs to the DEAD box helicase family
FA592_RS11525	COG2964	Protein conserved in bacteria
FA592_RS11530	COG2084	Dehydrogenase
FA592_RS11550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FA592_RS11555	COG2226	methyltransferase
FA592_RS11570	COG3437	response regulator, receiver
FA592_RS11570	COG0784	Response regulator, receiver
FA592_RS11585	COG0217	transcriptional regulatory protein
FA592_RS11595	COG2358	TRAP transporter, solute receptor (TAXI family
FA592_RS11610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FA592_RS11635	COG0582	viral genome integration into host DNA
FA592_RS11660	COG1538	Outer membrane efflux protein
FA592_RS11665	COG2274	protein secretion by the type I secretion system
FA592_RS11670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FA592_RS11735	COG2308	Evidence 4 Homologs of previously reported genes of
FA592_RS11750	COG2966	Psort location CytoplasmicMembrane, score
FA592_RS11755	COG3610	response to peptide
FA592_RS11760	COG2217	Heavy metal translocating P-type atpase
FA592_RS11780	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FA592_RS11785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FA592_RS11785	COG2169	Transcriptional regulator
FA592_RS11795	COG0352	thiamine-phosphate diphosphorylase activity
FA592_RS11810	COG1272	protein, Hemolysin III
FA592_RS11815	COG1280	lysine exporter protein (LysE YggA)
FA592_RS11820	COG0697	spore germination
FA592_RS11840	COG2176	DNA-directed DNA polymerase activity
FA592_RS11865	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FA592_RS11875	COG0501	Belongs to the peptidase M48B family
FA592_RS11895	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FA592_RS11900	COG2201	protein-glutamate methylesterase activity
FA592_RS11905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FA592_RS11915	COG0133	tryptophan synthase activity
FA592_RS11920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FA592_RS11930	COG0698	ribose 5-phosphate isomerase
FA592_RS11935	COG1994	Peptidase M50
FA592_RS11940	COG0681	Belongs to the peptidase S26 family
FA592_RS11945	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FA592_RS11955	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FA592_RS11970	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FA592_RS11980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FA592_RS11985	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FA592_RS12010	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FA592_RS12015	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FA592_RS12020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FA592_RS12025	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FA592_RS12030	COG0629	single-stranded DNA binding
FA592_RS12035	COG0360	Binds together with S18 to 16S ribosomal RNA
FA592_RS12040	COG1466	dna polymerase III delta subunit
FA592_RS12045	COG0557	exoribonuclease II activity
FA592_RS12055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FA592_RS12060	COG2894	cell division
FA592_RS12065	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FA592_RS12070	COG2861	carbohydrate metabolic process
FA592_RS12080	COG0730	response to heat
FA592_RS12085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FA592_RS12095	COG1760	l-serine dehydratase
FA592_RS12100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FA592_RS12105	COG2860	membrane
FA592_RS12110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FA592_RS12125	COG0736	holo-[acyl-carrier-protein] synthase activity
FA592_RS12130	COG1580	Controls the rotational direction of flagella during chemotaxis
FA592_RS12135	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FA592_RS12140	COG0552	protein localization to endoplasmic reticulum
FA592_RS12145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FA592_RS12155	COG1418	mRNA catabolic process
FA592_RS12160	COG1132	(ABC) transporter
FA592_RS12185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FA592_RS12195	COG0745	RESPONSE REGULATOR receiver
FA592_RS12210	COG4191	Histidine kinase
FA592_RS12210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FA592_RS12225	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FA592_RS12290	COG1408	metallophosphoesterase
FA592_RS12325	COG1136	(ABC) transporter
FA592_RS12345	COG0546	phosphoglycolate phosphatase activity
FA592_RS12350	COG1454	alcohol dehydrogenase
FA592_RS12380	COG0242	peptide deformylase activity
FA592_RS12385	COG0824	Thioesterase
FA592_RS12400	COG1573	uracil-dna glycosylase
FA592_RS12415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FA592_RS12430	COG0745	RESPONSE REGULATOR receiver
FA592_RS12435	COG2199	diguanylate cyclase activity
FA592_RS12435	COG2200	EAL domain
FA592_RS12435	COG3287	FIST C domain
FA592_RS12450	COG0426	domain, Protein
FA592_RS12465	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FA592_RS12470	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FA592_RS12475	COG1053	succinate dehydrogenase
FA592_RS12500	COG2040	homocysteine
FA592_RS12510	COG1196	nuclear chromosome segregation
FA592_RS12510	COG3264	Mechanosensitive ion channel
FA592_RS12515	COG1433	Dinitrogenase iron-molybdenum cofactor
FA592_RS12550	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FA592_RS12565	COG0346	lactoylglutathione lyase activity
FA592_RS12600	COG1451	nucleotide metabolic process
FA592_RS12620	COG2207	Transcriptional regulator
FA592_RS12640	COG0697	spore germination
FA592_RS12650	COG3706	GGDEF domain
FA592_RS12660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FA592_RS12675	COG3706	GGDEF domain
FA592_RS12690	COG0840	transmembrane signaling receptor activity
FA592_RS12710	COG1276	copper resistance
FA592_RS12715	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FA592_RS12730	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FA592_RS12735	COG0784	Response regulator, receiver
FA592_RS12790	COG0642	Histidine kinase
FA592_RS12795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FA592_RS12795	COG3153	acetyltransferase
FA592_RS12825	COG0493	'glutamate synthase
FA592_RS12830	COG0375	protein maturation
FA592_RS12835	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FA592_RS12845	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_RS12855	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FA592_RS12890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FA592_RS12895	COG0523	cobalamin synthesis protein
FA592_RS12900	COG2879	small protein
FA592_RS12905	COG1966	Carbon starvation protein
FA592_RS12915	COG1053	succinate dehydrogenase
FA592_RS12950	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FA592_RS12955	COG0585	pseudouridine synthase activity
FA592_RS12965	COG0569	domain protein
FA592_RS12965	COG0475	glutathione-regulated potassium exporter activity
FA592_RS12980	COG3706	GGDEF domain
FA592_RS12985	COG0351	phosphomethylpyrimidine kinase
FA592_RS12995	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FA592_RS13005	COG0840	transmembrane signaling receptor activity
FA592_RS13020	COG0488	(ABC) transporter
FA592_RS13025	COG1360	Flagellar Motor Protein
FA592_RS13030	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FA592_RS13035	COG1309	transcriptional regulator
FA592_RS13065	COG0778	Nitroreductase
FA592_RS13080	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FA592_RS13095	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FA592_RS13105	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FA592_RS13125	COG4145	pantothenate transmembrane transporter activity
FA592_RS13140	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FA592_RS13155	COG0742	ribosomal rna small subunit methyltransferase
FA592_RS13165	COG1706	bacterial-type flagellum-dependent cell motility
FA592_RS13170	COG3951	Flagellar rod assembly protein muramidase FlgJ
FA592_RS13190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FA592_RS13200	COG0659	secondary active sulfate transmembrane transporter activity
FA592_RS13205	COG1942	4-Oxalocrotonate Tautomerase
FA592_RS13210	COG0356	it plays a direct role in the translocation of protons across the membrane
FA592_RS13220	COG0352	thiamine-phosphate diphosphorylase activity
FA592_RS13225	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FA592_RS13235	COG1472	Belongs to the glycosyl hydrolase 3 family
FA592_RS13240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FA592_RS13245	COG0101	tRNA pseudouridine synthase activity
FA592_RS13255	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FA592_RS13265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FA592_RS13270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FA592_RS13275	COG1338	Plays a role in the flagellum-specific transport system
FA592_RS13280	COG0676	glucose-6-phosphate 1-epimerase activity
FA592_RS13285	COG2249	NAD(P)H dehydrogenase (quinone) activity
FA592_RS13300	COG3174	membrane
FA592_RS13305	COG1032	radical SAM domain protein
FA592_RS13310	COG0166	Belongs to the GPI family
FA592_RS13330	COG3259	Nickel-dependent hydrogenase
FA592_RS13335	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FA592_RS13340	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FA592_RS13345	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
FA592_RS13350	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FA592_RS13355	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FA592_RS13360	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FA592_RS13375	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FA592_RS13380	COG0298	carbon dioxide binding
FA592_RS13385	COG0409	Hydrogenase expression formation protein
FA592_RS13390	COG0309	Hydrogenase expression formation protein (HypE)
FA592_RS13395	COG0375	protein maturation
FA592_RS13400	COG1247	-acetyltransferase
FA592_RS13405	COG0546	phosphoglycolate phosphatase activity
FA592_RS13425	COG0039	L-malate dehydrogenase activity
FA592_RS13430	COG0045	succinate-CoA ligase (ADP-forming) activity
FA592_RS13435	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FA592_RS13445	COG0674	pyruvate-flavodoxin oxidoreductase activity
FA592_RS13445	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FA592_RS13540	COG0114	fumarate hydratase activity
FA592_RS13565	COG0842	Transport permease protein
FA592_RS13565	COG1129	ABC transporter
FA592_RS13570	COG0842	Transport permease protein
FA592_RS13575	COG0842	Transport permease protein
FA592_RS13580	COG2095	MarC family integral membrane protein
FA592_RS13600	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FA592_RS13605	COG0750	zinc metalloprotease
FA592_RS13610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FA592_RS13615	COG1028	Short-chain dehydrogenase reductase Sdr
FA592_RS13620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FA592_RS13630	COG0167	dihydroorotate dehydrogenase activity
FA592_RS13635	COG1132	(ABC) transporter
FA592_RS13640	COG0215	cysteine-tRNA ligase activity
FA592_RS13645	COG0728	peptidoglycan biosynthetic process
FA592_RS13655	COG0632	four-way junction helicase activity
FA592_RS13675	COG1254	Belongs to the acylphosphatase family
FA592_RS13680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FA592_RS13685	COG0857	belongs to the CobB CobQ family
FA592_RS13685	COG0280	phosphate acetyltransferase
FA592_RS13690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FA592_RS13695	COG1610	YqeY-like protein
FA592_RS13755	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FA592_RS13760	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FA592_RS13775	COG0137	argininosuccinate synthase activity
FA592_RS13780	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FA592_RS13785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FA592_RS13790	COG0802	atpase or kinase
FA592_RS13795	COG1137	ATPase activity
FA592_RS13890	COG3093	addiction module antidote protein HigA
FA592_RS13950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FA592_RS14025	COG1192	Involved in chromosome partitioning
FA592_RS14030	COG1192	Involved in chromosome partitioning
FA592_RS14120	COG3106	COG3106 Predicted ATPase
FA592_RS14125	COG3106	COG3106 Predicted ATPase
FA592_RS14135	COG0681	Belongs to the peptidase S26 family
FA592_RS14145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII