locus-tag	class	description
Sdiek1_RS00010	COG0592	DNA-directed DNA polymerase activity
Sdiek1_RS00015	COG0187	DNA topoisomerase II activity
Sdiek1_RS00020	COG5001	Diguanylate cyclase
Sdiek1_RS00025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Sdiek1_RS00040	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Sdiek1_RS00045	COG1194	a g-specific adenine glycosylase
Sdiek1_RS00050	COG4175	Glycine betaine
Sdiek1_RS00055	COG4176	ABC-type proline glycine betaine transport system permease component
Sdiek1_RS00060	COG2113	Glycine betaine
Sdiek1_RS00065	COG2814	Major facilitator Superfamily
Sdiek1_RS00080	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Sdiek1_RS00090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Sdiek1_RS00095	COG0066	3-isopropylmalate dehydratase activity
Sdiek1_RS00135	COG0840	transmembrane signaling receptor activity
Sdiek1_RS00155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Sdiek1_RS00160	COG1335	isochorismatase
Sdiek1_RS00190	COG1355	regulation of microtubule-based process
Sdiek1_RS00200	COG2078	PFAM AMMECR1 domain protein
Sdiek1_RS00225	COG1917	Cupin 2, conserved barrel domain protein
Sdiek1_RS00225	COG2169	Transcriptional regulator
Sdiek1_RS00235	COG3150	esterase
Sdiek1_RS00245	COG3383	formate dehydrogenase (NAD+) activity
Sdiek1_RS00380	COG0129	dihydroxy-acid dehydratase activity
Sdiek1_RS00385	COG2095	MarC family integral membrane protein
Sdiek1_RS00410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Sdiek1_RS00420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Sdiek1_RS00430	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Sdiek1_RS00430	COG1328	CTP reductase activity
Sdiek1_RS00435	COG1794	racemase activity, acting on amino acids and derivatives
Sdiek1_RS00440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Sdiek1_RS00445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Sdiek1_RS00450	COG0564	pseudouridine synthase activity
Sdiek1_RS00455	COG0179	Fumarylacetoacetate (FAA) hydrolase
Sdiek1_RS00460	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Sdiek1_RS00470	COG0107	imidazoleglycerol-phosphate synthase activity
Sdiek1_RS00480	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Sdiek1_RS00485	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Sdiek1_RS00485	COG0517	IMP dehydrogenase activity
Sdiek1_RS00490	COG1187	pseudouridine synthase activity
Sdiek1_RS00495	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Sdiek1_RS00495	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Sdiek1_RS00505	COG2257	FlhB HrpN YscU SpaS Family
Sdiek1_RS00525	COG0237	dephospho-CoA kinase activity
Sdiek1_RS00530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Sdiek1_RS00540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Sdiek1_RS00545	COG0268	Binds directly to 16S ribosomal RNA
Sdiek1_RS00550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Sdiek1_RS00565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Sdiek1_RS00575	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Sdiek1_RS00580	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Sdiek1_RS00585	COG0348	domain, Protein
Sdiek1_RS00595	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Sdiek1_RS00610	COG0754	glutathionylspermidine amidase activity
Sdiek1_RS00615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Sdiek1_RS00660	COG0642	Histidine kinase
Sdiek1_RS00665	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS00685	COG1127	ABC transporter
Sdiek1_RS00690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Sdiek1_RS00710	COG0840	transmembrane signaling receptor activity
Sdiek1_RS00720	COG0784	Response regulator, receiver
Sdiek1_RS00720	COG3437	response regulator, receiver
Sdiek1_RS00730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Sdiek1_RS00740	COG5002	protein histidine kinase activity
Sdiek1_RS00750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Sdiek1_RS00760	COG0004	ammonium transporteR
Sdiek1_RS00765	COG0667	Aldo Keto reductase
Sdiek1_RS00775	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS00790	COG0765	amino acid transport
Sdiek1_RS00830	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Sdiek1_RS00845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Sdiek1_RS00850	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_RS00855	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_RS00860	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_RS00865	COG0649	NAD binding
Sdiek1_RS00885	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Sdiek1_RS00890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_RS00895	COG0839	Belongs to the complex I subunit 6 family
Sdiek1_RS00900	COG0713	ATP synthesis coupled electron transport
Sdiek1_RS00905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Sdiek1_RS00910	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_RS00915	COG1007	ATP synthesis coupled electron transport
Sdiek1_RS00925	COG1012	belongs to the aldehyde dehydrogenase family
Sdiek1_RS00930	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Sdiek1_RS00950	COG0840	transmembrane signaling receptor activity
Sdiek1_RS00955	COG0840	transmembrane signaling receptor activity
Sdiek1_RS00960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Sdiek1_RS00965	COG0303	'Molybdopterin
Sdiek1_RS00975	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Sdiek1_RS00980	COG0254	rRNA binding
Sdiek1_RS00985	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Sdiek1_RS00990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Sdiek1_RS01005	COG0436	Aminotransferase
Sdiek1_RS01010	COG0460	homoserine dehydrogenase
Sdiek1_RS01015	COG0792	nuclease activity
Sdiek1_RS01020	COG3118	belongs to the thioredoxin family
Sdiek1_RS01025	COG0492	ferredoxin-NADP+ reductase activity
Sdiek1_RS01030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Sdiek1_RS01035	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Sdiek1_RS01040	COG1242	4 iron, 4 sulfur cluster binding
Sdiek1_RS01055	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Sdiek1_RS01055	COG0140	phosphoribosyl-ATP diphosphatase activity
Sdiek1_RS01070	COG1012	belongs to the aldehyde dehydrogenase family
Sdiek1_RS01075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Sdiek1_RS01090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Sdiek1_RS01095	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Sdiek1_RS01100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Sdiek1_RS01115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Sdiek1_RS01135	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Sdiek1_RS01140	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Sdiek1_RS01155	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Sdiek1_RS01165	COG0835	chemotaxis
Sdiek1_RS01165	COG0784	Response regulator, receiver
Sdiek1_RS01170	COG0784	Response regulator, receiver
Sdiek1_RS01170	COG0643	Histidine kinase
Sdiek1_RS01170	COG2198	Histidine kinase
Sdiek1_RS01175	COG0835	chemotaxis
Sdiek1_RS01190	COG0560	Phosphoserine phosphatase
Sdiek1_RS01210	COG0193	aminoacyl-tRNA hydrolase activity
Sdiek1_RS01220	COG0019	diaminopimelate decarboxylase activity
Sdiek1_RS01225	COG1605	Chorismate mutase
Sdiek1_RS01225	COG0077	Prephenate dehydratase
Sdiek1_RS01230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Sdiek1_RS01240	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Sdiek1_RS01250	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Sdiek1_RS01255	COG0735	belongs to the Fur family
Sdiek1_RS01260	COG0450	alkyl hydroperoxide reductase
Sdiek1_RS01275	COG0105	UTP biosynthetic process
Sdiek1_RS01285	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Sdiek1_RS01290	COG0416	fatty acid biosynthetic process
Sdiek1_RS01295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Sdiek1_RS01300	COG0714	Associated with various cellular activities
Sdiek1_RS01320	COG2304	oxidoreductase activity
Sdiek1_RS01330	COG0287	Prephenate dehydrogenase
Sdiek1_RS01335	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Sdiek1_RS01345	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_RS01355	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS01365	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Sdiek1_RS01375	COG0157	Belongs to the NadC ModD family
Sdiek1_RS01380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Sdiek1_RS01395	COG0850	regulation of cytokinetic process
Sdiek1_RS01400	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Sdiek1_RS01410	COG0083	homoserine kinase activity
Sdiek1_RS01430	COG0779	Required for maturation of 30S ribosomal subunits
Sdiek1_RS01435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Sdiek1_RS01435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Sdiek1_RS01450	COG5001	Diguanylate cyclase
Sdiek1_RS01460	COG5002	protein histidine kinase activity
Sdiek1_RS01475	COG3258	Cytochrome c
Sdiek1_RS01485	COG1242	4 iron, 4 sulfur cluster binding
Sdiek1_RS01490	COG0243	molybdopterin cofactor binding
Sdiek1_RS01495	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_RS01500	COG3301	Polysulphide reductase, NrfD
Sdiek1_RS01515	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_RS01520	COG3301	Polysulphide reductase, NrfD
Sdiek1_RS01525	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS01530	COG5002	protein histidine kinase activity
Sdiek1_RS01540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Sdiek1_RS01560	COG0848	biopolymer transport protein
Sdiek1_RS01565	COG0811	peptide transport
Sdiek1_RS01580	COG1227	inorganic diphosphatase activity
Sdiek1_RS01595	COG2226	methyltransferase
Sdiek1_RS01600	COG1570	exodeoxyribonuclease VII activity
Sdiek1_RS01620	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Sdiek1_RS01625	COG1028	Short-chain dehydrogenase reductase Sdr
Sdiek1_RS01630	COG2207	Transcriptional regulator
Sdiek1_RS01635	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Sdiek1_RS01640	COG0583	DNA-binding transcription factor activity
Sdiek1_RS01645	COG2855	membrane
Sdiek1_RS01650	COG0386	Belongs to the glutathione peroxidase family
Sdiek1_RS01655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Sdiek1_RS01665	COG0402	S-adenosylhomocysteine deaminase activity
Sdiek1_RS01670	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Sdiek1_RS01675	COG0006	proline dipeptidase activity
Sdiek1_RS01680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Sdiek1_RS01685	COG1419	protein localization to endoplasmic reticulum
Sdiek1_RS01690	COG0455	bacterial-type flagellum organization
Sdiek1_RS01700	COG1191	sigma factor activity
Sdiek1_RS01705	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Sdiek1_RS01715	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Sdiek1_RS01715	COG1776	CheC inhibitor of MCP methylation
Sdiek1_RS01725	COG0463	Glycosyl transferase, family 2
Sdiek1_RS01735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Sdiek1_RS01755	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Sdiek1_RS01765	COG1040	competence protein
Sdiek1_RS01800	COG2204	response regulator
Sdiek1_RS01805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Sdiek1_RS01815	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Sdiek1_RS01820	COG0731	radical SAM domain protein
Sdiek1_RS01830	COG2358	TRAP transporter, solute receptor (TAXI family
Sdiek1_RS01840	COG0582	viral genome integration into host DNA
Sdiek1_RS01860	COG3177	Filamentation induced by cAMP protein fic
Sdiek1_RS01865	COG1061	Type III restriction enzyme res subunit
Sdiek1_RS01870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Sdiek1_RS01920	COG1464	Belongs to the NlpA lipoprotein family
Sdiek1_RS01925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Sdiek1_RS01930	COG2011	ABC-type metal ion transport system permease component
Sdiek1_RS01935	COG0306	phosphate transporter
Sdiek1_RS01940	COG0039	L-malate dehydrogenase activity
Sdiek1_RS01945	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Sdiek1_RS01955	COG1834	amidinotransferase
Sdiek1_RS01965	COG3708	Transcriptional regulator
Sdiek1_RS01965	COG2207	Transcriptional regulator
Sdiek1_RS01970	COG1053	succinate dehydrogenase
Sdiek1_RS02015	COG2200	EAL domain
Sdiek1_RS02015	COG2199	diguanylate cyclase activity
Sdiek1_RS02015	COG3287	FIST C domain
Sdiek1_RS02035	COG3118	belongs to the thioredoxin family
Sdiek1_RS02045	COG4336	lyase activity
Sdiek1_RS02070	COG4628	conserved protein (DUF2132)
Sdiek1_RS02075	COG4221	oxidoreductase activity
Sdiek1_RS02080	COG0683	leucine binding
Sdiek1_RS02110	COG3022	response to hydroperoxide
Sdiek1_RS02135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Sdiek1_RS02140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Sdiek1_RS02155	COG0250	Participates in transcription elongation, termination and antitermination
Sdiek1_RS02160	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Sdiek1_RS02165	COG0081	regulation of translation
Sdiek1_RS02170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Sdiek1_RS02175	COG0222	ribosome binding
Sdiek1_RS02180	COG0085	RNA polymerase activity
Sdiek1_RS02185	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Sdiek1_RS02190	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Sdiek1_RS02200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Sdiek1_RS02210	COG0697	spore germination
Sdiek1_RS02215	COG0656	L-ascorbic acid biosynthetic process
Sdiek1_RS02225	COG0534	Mate efflux family protein
Sdiek1_RS02270	COG1034	ATP synthesis coupled electron transport
Sdiek1_RS02275	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Sdiek1_RS02280	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_RS02290	COG0713	ATP synthesis coupled electron transport
Sdiek1_RS02295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Sdiek1_RS02305	COG1007	ATP synthesis coupled electron transport
Sdiek1_RS02330	COG0649	NAD binding
Sdiek1_RS02330	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_RS02335	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_RS02340	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_RS02355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Sdiek1_RS02375	COG0357	Ribosomal RNA small subunit methyltransferase G
Sdiek1_RS02380	COG0840	transmembrane signaling receptor activity
Sdiek1_RS02380	COG3290	protein histidine kinase activity
Sdiek1_RS02390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Sdiek1_RS02395	COG1970	mechanosensitive ion channel activity
Sdiek1_RS02405	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Sdiek1_RS02410	COG0113	porphobilinogen synthase activity
Sdiek1_RS02425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Sdiek1_RS02430	COG0247	lactate metabolic process
Sdiek1_RS02470	COG3012	SEC-C Motif Domain Protein
Sdiek1_RS02485	COG3706	GGDEF domain
Sdiek1_RS02490	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Sdiek1_RS02500	COG1053	succinate dehydrogenase
Sdiek1_RS02505	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Sdiek1_RS02515	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Sdiek1_RS02520	COG0628	permease
Sdiek1_RS02525	COG2255	four-way junction helicase activity
Sdiek1_RS02530	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Sdiek1_RS02540	COG0159	tryptophan synthase activity
Sdiek1_RS02560	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Sdiek1_RS02565	COG1136	(ABC) transporter
Sdiek1_RS02570	COG1684	flagellar biosynthetic protein fliR
Sdiek1_RS02580	COG0194	GDP metabolic process
Sdiek1_RS02585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Sdiek1_RS02590	COG0018	arginyl-trna synthetase
Sdiek1_RS02600	COG2199	diguanylate cyclase activity
Sdiek1_RS02600	COG3287	FIST C domain
Sdiek1_RS02600	COG2200	EAL domain
Sdiek1_RS02615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Sdiek1_RS02620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Sdiek1_RS02630	COG0149	triose-phosphate isomerase activity
Sdiek1_RS02635	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Sdiek1_RS02645	COG0195	Participates in both transcription termination and antitermination
Sdiek1_RS02680	COG0037	tRNA processing
Sdiek1_RS02685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Sdiek1_RS02690	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Sdiek1_RS02720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Sdiek1_RS02725	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Sdiek1_RS02730	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Sdiek1_RS02740	COG1151	hydroxylamine reductase activity
Sdiek1_RS02745	COG3040	lipid binding
Sdiek1_RS02750	COG1401	restriction endodeoxyribonuclease activity
Sdiek1_RS02760	COG2326	polyphosphate kinase activity
Sdiek1_RS02775	COG0723	plastoquinol--plastocyanin reductase activity
Sdiek1_RS02780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Sdiek1_RS02790	COG1981	membrane
Sdiek1_RS02795	COG0513	Belongs to the DEAD box helicase family
Sdiek1_RS02800	COG2610	gluconate transmembrane transporter activity
Sdiek1_RS02805	COG1944	ATP diphosphatase activity
Sdiek1_RS02825	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS02860	COG0411	ABC transporter
Sdiek1_RS02910	COG1058	Belongs to the CinA family
Sdiek1_RS02910	COG1546	Belongs to the CinA family
Sdiek1_RS02915	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Sdiek1_RS02925	COG0516	GMP reductase activity
Sdiek1_RS02925	COG0517	IMP dehydrogenase activity
Sdiek1_RS02945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Sdiek1_RS02950	COG0436	Aminotransferase
Sdiek1_RS02965	COG1193	negative regulation of DNA recombination
Sdiek1_RS02970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Sdiek1_RS02975	COG0251	oxidation-reduction process
Sdiek1_RS02980	COG0579	oxidoreductase
Sdiek1_RS02985	COG2226	methyltransferase
Sdiek1_RS03000	COG3409	Peptidoglycan-binding domain 1 protein
Sdiek1_RS03000	COG0793	Belongs to the peptidase S41A family
Sdiek1_RS03020	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Sdiek1_RS03025	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Sdiek1_RS03030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Sdiek1_RS03035	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Sdiek1_RS03040	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Sdiek1_RS03050	COG1192	Involved in chromosome partitioning
Sdiek1_RS03055	COG1475	DNA binding
Sdiek1_RS03065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Sdiek1_RS03070	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Sdiek1_RS03080	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Sdiek1_RS03095	COG0811	peptide transport
Sdiek1_RS03100	COG0848	biopolymer transport protein
Sdiek1_RS03110	COG0823	Involved in the tonB-independent uptake of proteins
Sdiek1_RS03125	COG1047	Peptidyl-prolyl cis-trans
Sdiek1_RS03135	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Sdiek1_RS03140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Sdiek1_RS03145	COG0037	tRNA processing
Sdiek1_RS03160	COG0493	'glutamate synthase
Sdiek1_RS03170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Sdiek1_RS03175	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Sdiek1_RS03180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Sdiek1_RS03190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Sdiek1_RS03210	COG1776	CheC inhibitor of MCP methylation
Sdiek1_RS03210	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Sdiek1_RS03260	COG0748	coenzyme F420 binding
Sdiek1_RS03275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Sdiek1_RS03285	COG0454	-acetyltransferase
Sdiek1_RS03295	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Sdiek1_RS03305	COG1113	amino acid transport
Sdiek1_RS03310	COG0730	response to heat
Sdiek1_RS03315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Sdiek1_RS03320	COG1301	dicarboxylic acid transport
Sdiek1_RS03325	COG1301	dicarboxylic acid transport
Sdiek1_RS03335	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Sdiek1_RS03335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Sdiek1_RS03340	COG1971	Probably functions as a manganese efflux pump
Sdiek1_RS03355	COG0484	heat shock protein binding
Sdiek1_RS03365	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS03370	COG0642	Histidine kinase
Sdiek1_RS03375	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Sdiek1_RS03390	COG0318	PFAM AMP-dependent synthetase and ligase
Sdiek1_RS03395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Sdiek1_RS03400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Sdiek1_RS03415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Sdiek1_RS03420	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Sdiek1_RS03435	COG3706	GGDEF domain
Sdiek1_RS03445	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Sdiek1_RS03480	COG5002	protein histidine kinase activity
Sdiek1_RS03480	COG0784	Response regulator, receiver
Sdiek1_RS03480	COG2205	protein histidine kinase activity
Sdiek1_RS03495	COG0322	excinuclease ABC activity
Sdiek1_RS03505	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Sdiek1_RS03510	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Sdiek1_RS03515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Sdiek1_RS03515	COG0519	Catalyzes the synthesis of GMP from XMP
Sdiek1_RS03545	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Sdiek1_RS03565	COG0511	ligase activity, forming carbon-carbon bonds
Sdiek1_RS03570	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Sdiek1_RS03575	COG0165	Argininosuccinate lyase
Sdiek1_RS03580	COG0537	adenosine 5'-monophosphoramidase activity
Sdiek1_RS03585	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Sdiek1_RS03590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Sdiek1_RS03590	COG0072	phenylalanine-tRNA ligase activity
Sdiek1_RS03595	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Sdiek1_RS03600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Sdiek1_RS03605	COG0539	negative regulation of cytoplasmic translation
Sdiek1_RS03605	COG1185	polyribonucleotide nucleotidyltransferase activity
Sdiek1_RS03615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Sdiek1_RS03625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Sdiek1_RS03635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Sdiek1_RS03645	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Sdiek1_RS03650	COG0840	transmembrane signaling receptor activity
Sdiek1_RS03660	COG0840	transmembrane signaling receptor activity
Sdiek1_RS03670	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Sdiek1_RS03685	COG2081	HI0933 family
Sdiek1_RS03695	COG1981	membrane
Sdiek1_RS03710	COG1902	pentaerythritol trinitrate reductase activity
Sdiek1_RS03715	COG1538	Outer membrane efflux protein
Sdiek1_RS03725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Sdiek1_RS03730	COG0840	transmembrane signaling receptor activity
Sdiek1_RS03735	COG0840	transmembrane signaling receptor activity
Sdiek1_RS03735	COG0840	transmembrane signaling receptor activity
Sdiek1_RS03745	COG0587	DNA-directed DNA polymerase activity
Sdiek1_RS03750	COG0642	Histidine kinase
Sdiek1_RS03760	COG1346	cytolysis
Sdiek1_RS03765	COG1380	Effector of murein hydrolase LrgA
Sdiek1_RS03785	COG0772	Belongs to the SEDS family
Sdiek1_RS03790	COG0564	pseudouridine synthase activity
Sdiek1_RS03800	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Sdiek1_RS03805	COG1136	(ABC) transporter
Sdiek1_RS03820	COG0528	UMP kinase activity
Sdiek1_RS03825	COG1758	RNA polymerase activity
Sdiek1_RS03830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Sdiek1_RS03835	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Sdiek1_RS03840	COG2070	2-Nitropropane dioxygenase
Sdiek1_RS03845	COG0860	N-Acetylmuramoyl-L-alanine amidase
Sdiek1_RS03855	COG0563	adenylate kinase activity
Sdiek1_RS03860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Sdiek1_RS03865	COG3706	GGDEF domain
Sdiek1_RS03875	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Sdiek1_RS03880	COG0497	DNA recombination
Sdiek1_RS03890	COG0084	hydrolase, TatD family'
Sdiek1_RS03900	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Sdiek1_RS03905	COG0131	Imidazoleglycerol-phosphate dehydratase
Sdiek1_RS03910	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Sdiek1_RS03925	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Sdiek1_RS03940	COG0768	penicillin binding
Sdiek1_RS03965	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Sdiek1_RS03965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Sdiek1_RS03975	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Sdiek1_RS04000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Sdiek1_RS04005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Sdiek1_RS04025	COG0471	metal ion transport
Sdiek1_RS04030	COG4191	Histidine kinase
Sdiek1_RS04035	COG0840	transmembrane signaling receptor activity
Sdiek1_RS04045	COG0583	DNA-binding transcription factor activity
Sdiek1_RS04050	COG1053	succinate dehydrogenase
Sdiek1_RS04055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Sdiek1_RS04060	COG2048	Heterodisulfide reductase, subunit B
Sdiek1_RS04070	COG3290	protein histidine kinase activity
Sdiek1_RS04070	COG0840	transmembrane signaling receptor activity
Sdiek1_RS04085	COG3005	denitrification pathway
Sdiek1_RS04090	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Sdiek1_RS04095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Sdiek1_RS04095	COG1333	cytochrome c biogenesis protein
Sdiek1_RS04115	COG3545	Serine hydrolase
Sdiek1_RS04125	COG0463	Glycosyl transferase, family 2
Sdiek1_RS04130	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
Sdiek1_RS04140	COG0398	Pfam SNARE associated Golgi protein
Sdiek1_RS04155	COG0398	Pfam SNARE associated Golgi protein
Sdiek1_RS04160	COG2226	methyltransferase
Sdiek1_RS04175	COG0697	spore germination
Sdiek1_RS04185	COG1575	Belongs to the MenA family. Type 1 subfamily
Sdiek1_RS04195	COG4221	oxidoreductase activity
Sdiek1_RS04215	COG4716	Myosin-crossreactive antigen
Sdiek1_RS04270	COG0243	molybdopterin cofactor binding
Sdiek1_RS04275	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_RS04280	COG0348	domain, Protein
Sdiek1_RS04285	COG3043	anaerobic respiration
Sdiek1_RS04290	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_RS04290	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_RS04340	COG1271	oxidase subunit
Sdiek1_RS04370	COG0243	molybdopterin cofactor binding
Sdiek1_RS04385	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS04420	COG2863	cytochrome
Sdiek1_RS04425	COG0723	plastoquinol--plastocyanin reductase activity
Sdiek1_RS04430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Sdiek1_RS04445	COG2200	EAL domain
Sdiek1_RS04445	COG2199	diguanylate cyclase activity
Sdiek1_RS04445	COG3287	FIST C domain
Sdiek1_RS04455	COG0513	Belongs to the DEAD box helicase family
Sdiek1_RS04465	COG2964	Protein conserved in bacteria
Sdiek1_RS04470	COG2084	Dehydrogenase
Sdiek1_RS04475	COG3290	protein histidine kinase activity
Sdiek1_RS04475	COG0840	transmembrane signaling receptor activity
Sdiek1_RS04480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Sdiek1_RS04485	COG2226	methyltransferase
Sdiek1_RS04500	COG3437	response regulator, receiver
Sdiek1_RS04500	COG0784	Response regulator, receiver
Sdiek1_RS04515	COG0217	transcriptional regulatory protein
Sdiek1_RS04525	COG2358	TRAP transporter, solute receptor (TAXI family
Sdiek1_RS04540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Sdiek1_RS04770	COG1136	(ABC) transporter
Sdiek1_RS04795	COG0348	domain, Protein
Sdiek1_RS04810	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_RS04825	COG4263	nitrous-oxide reductase activity
Sdiek1_RS04830	COG3852	Histidine kinase
Sdiek1_RS04840	COG2863	cytochrome
Sdiek1_RS04845	COG0723	plastoquinol--plastocyanin reductase activity
Sdiek1_RS04850	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Sdiek1_RS04855	COG2857	Cytochrome c1
Sdiek1_RS04870	COG2200	EAL domain
Sdiek1_RS04870	COG3287	FIST C domain
Sdiek1_RS04870	COG2199	diguanylate cyclase activity
Sdiek1_RS04880	COG0840	transmembrane signaling receptor activity
Sdiek1_RS04955	COG0243	molybdopterin cofactor binding
Sdiek1_RS04970	COG4191	Histidine kinase
Sdiek1_RS04980	COG1136	(ABC) transporter
Sdiek1_RS04985	COG0577	efflux transmembrane transporter activity
Sdiek1_RS04985	COG1136	(ABC) transporter
Sdiek1_RS05020	COG3842	ATPase activity
Sdiek1_RS05030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Sdiek1_RS05055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Sdiek1_RS05060	COG0640	Transcriptional regulator
Sdiek1_RS05065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Sdiek1_RS05080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Sdiek1_RS05085	COG4232	protein-disulfide reductase activity
Sdiek1_RS05195	COG3290	protein histidine kinase activity
Sdiek1_RS05195	COG0840	transmembrane signaling receptor activity
Sdiek1_RS05200	COG3045	CreA protein
Sdiek1_RS05205	COG2226	methyltransferase
Sdiek1_RS05215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Sdiek1_RS05225	COG3383	formate dehydrogenase (NAD+) activity
Sdiek1_RS05230	COG3383	formate dehydrogenase (NAD+) activity
Sdiek1_RS05235	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_RS05240	COG0651	ATP synthesis coupled electron transport
Sdiek1_RS05245	COG0650	Formate hydrogenlyase subunit 4
Sdiek1_RS05250	COG4237	Hydrogenase 4 membrane
Sdiek1_RS05255	COG0651	ATP synthesis coupled electron transport
Sdiek1_RS05260	COG3261	NADH dehydrogenase
Sdiek1_RS05260	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
Sdiek1_RS05270	COG3260	NADH ubiquinone oxidoreductase 20
Sdiek1_RS05285	COG2116	formate transmembrane transporter activity
Sdiek1_RS05300	COG3383	formate dehydrogenase (NAD+) activity
Sdiek1_RS05305	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS05315	COG0484	heat shock protein binding
Sdiek1_RS05320	COG0545	Peptidyl-prolyl cis-trans isomerase
Sdiek1_RS05325	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_RS05330	COG3301	Polysulphide reductase, NrfD
Sdiek1_RS05335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Sdiek1_RS05335	COG1333	cytochrome c biogenesis protein
Sdiek1_RS05360	COG1136	(ABC) transporter
Sdiek1_RS05400	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS05415	COG3279	Response regulator of the LytR AlgR family
Sdiek1_RS05420	COG3275	phosphorelay sensor kinase activity
Sdiek1_RS05430	COG1538	Outer membrane efflux protein
Sdiek1_RS05440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Sdiek1_RS05510	COG2308	Evidence 4 Homologs of previously reported genes of
Sdiek1_RS05525	COG2966	Psort location CytoplasmicMembrane, score
Sdiek1_RS05530	COG3610	response to peptide
Sdiek1_RS05535	COG2217	Heavy metal translocating P-type atpase
Sdiek1_RS05550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Sdiek1_RS05555	COG2169	Transcriptional regulator
Sdiek1_RS05555	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Sdiek1_RS05580	COG1272	protein, Hemolysin III
Sdiek1_RS05590	COG0697	spore germination
Sdiek1_RS05695	COG2176	DNA-directed DNA polymerase activity
Sdiek1_RS05700	COG0798	PFAM Bile acid sodium symporter
Sdiek1_RS05705	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Sdiek1_RS05715	COG0501	Belongs to the peptidase M48B family
Sdiek1_RS05735	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Sdiek1_RS05740	COG2201	protein-glutamate methylesterase activity
Sdiek1_RS05745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Sdiek1_RS05755	COG0133	tryptophan synthase activity
Sdiek1_RS05760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Sdiek1_RS05770	COG0698	ribose 5-phosphate isomerase
Sdiek1_RS05775	COG1994	Peptidase M50
Sdiek1_RS05780	COG0681	Belongs to the peptidase S26 family
Sdiek1_RS05785	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Sdiek1_RS05795	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Sdiek1_RS05810	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Sdiek1_RS05815	COG0612	Peptidase, M16
Sdiek1_RS05855	COG2133	pyrroloquinoline quinone binding
Sdiek1_RS05855	COG5183	chlorophyll binding
Sdiek1_RS05865	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Sdiek1_RS05875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Sdiek1_RS05880	COG0629	single-stranded DNA binding
Sdiek1_RS05890	COG1466	dna polymerase III delta subunit
Sdiek1_RS05895	COG0557	exoribonuclease II activity
Sdiek1_RS05905	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Sdiek1_RS05910	COG2894	cell division
Sdiek1_RS05915	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Sdiek1_RS05920	COG2861	carbohydrate metabolic process
Sdiek1_RS05930	COG0730	response to heat
Sdiek1_RS05935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Sdiek1_RS05945	COG1760	l-serine dehydratase
Sdiek1_RS05950	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Sdiek1_RS05955	COG2860	membrane
Sdiek1_RS05960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Sdiek1_RS05975	COG0736	holo-[acyl-carrier-protein] synthase activity
Sdiek1_RS05980	COG1580	Controls the rotational direction of flagella during chemotaxis
Sdiek1_RS05985	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Sdiek1_RS05990	COG0552	protein localization to endoplasmic reticulum
Sdiek1_RS05995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Sdiek1_RS06005	COG1418	mRNA catabolic process
Sdiek1_RS06010	COG1132	(ABC) transporter
Sdiek1_RS06035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Sdiek1_RS06050	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS06060	COG5002	protein histidine kinase activity
Sdiek1_RS06060	COG5001	Diguanylate cyclase
Sdiek1_RS06075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Sdiek1_RS06135	COG1408	metallophosphoesterase
Sdiek1_RS06140	COG2353	YceI-like domain
Sdiek1_RS06155	COG1136	(ABC) transporter
Sdiek1_RS06190	COG1454	alcohol dehydrogenase
Sdiek1_RS06230	COG0242	peptide deformylase activity
Sdiek1_RS06235	COG0824	Thioesterase
Sdiek1_RS06250	COG1573	uracil-dna glycosylase
Sdiek1_RS06265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Sdiek1_RS06280	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS06285	COG2200	EAL domain
Sdiek1_RS06285	COG3287	FIST C domain
Sdiek1_RS06285	COG2199	diguanylate cyclase activity
Sdiek1_RS06300	COG0426	domain, Protein
Sdiek1_RS06320	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Sdiek1_RS06325	COG1053	succinate dehydrogenase
Sdiek1_RS06325	COG3976	FMN-binding domain protein
Sdiek1_RS06350	COG2040	homocysteine
Sdiek1_RS06360	COG3264	Mechanosensitive ion channel
Sdiek1_RS06360	COG1196	nuclear chromosome segregation
Sdiek1_RS06365	COG1433	Dinitrogenase iron-molybdenum cofactor
Sdiek1_RS06375	COG0716	FMN binding
Sdiek1_RS06400	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Sdiek1_RS06415	COG0346	lactoylglutathione lyase activity
Sdiek1_RS06455	COG1451	nucleotide metabolic process
Sdiek1_RS06495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Sdiek1_RS06530	COG3706	GGDEF domain
Sdiek1_RS06580	COG1276	copper resistance
Sdiek1_RS06585	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Sdiek1_RS06595	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Sdiek1_RS06600	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Sdiek1_RS06610	COG5002	protein histidine kinase activity
Sdiek1_RS06615	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS06625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Sdiek1_RS06625	COG3153	acetyltransferase
Sdiek1_RS06660	COG4565	transcriptional regulatory protein
Sdiek1_RS06670	COG5002	protein histidine kinase activity
Sdiek1_RS06685	COG0493	'glutamate synthase
Sdiek1_RS06690	COG0375	protein maturation
Sdiek1_RS06695	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_RS06705	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_RS06715	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Sdiek1_RS06735	COG1335	isochorismatase
Sdiek1_RS06755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Sdiek1_RS06760	COG0523	cobalamin synthesis protein
Sdiek1_RS06765	COG2879	small protein
Sdiek1_RS06770	COG1966	Carbon starvation protein
Sdiek1_RS06780	COG1053	succinate dehydrogenase
Sdiek1_RS06815	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Sdiek1_RS06820	COG0585	pseudouridine synthase activity
Sdiek1_RS06830	COG0475	glutathione-regulated potassium exporter activity
Sdiek1_RS06830	COG0569	domain protein
Sdiek1_RS06845	COG3706	GGDEF domain
Sdiek1_RS06855	COG0351	phosphomethylpyrimidine kinase
Sdiek1_RS06855	COG0352	thiamine-phosphate diphosphorylase activity
Sdiek1_RS06865	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Sdiek1_RS06875	COG0840	transmembrane signaling receptor activity
Sdiek1_RS06880	COG1234	tRNA 3'-trailer cleavage
Sdiek1_RS06890	COG0488	(ABC) transporter
Sdiek1_RS06895	COG1360	Flagellar Motor Protein
Sdiek1_RS06900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Sdiek1_RS06940	COG0415	Belongs to the DNA photolyase family
Sdiek1_RS06975	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Sdiek1_RS06990	COG4145	pantothenate transmembrane transporter activity
Sdiek1_RS07005	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Sdiek1_RS07020	COG0742	ribosomal rna small subunit methyltransferase
Sdiek1_RS07030	COG1706	bacterial-type flagellum-dependent cell motility
Sdiek1_RS07035	COG3951	Flagellar rod assembly protein muramidase FlgJ
Sdiek1_RS07065	COG0659	secondary active sulfate transmembrane transporter activity
Sdiek1_RS07070	COG1942	4-Oxalocrotonate Tautomerase
Sdiek1_RS07075	COG0356	it plays a direct role in the translocation of protons across the membrane
Sdiek1_RS07085	COG0352	thiamine-phosphate diphosphorylase activity
Sdiek1_RS07090	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Sdiek1_RS07105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Sdiek1_RS07110	COG0101	tRNA pseudouridine synthase activity
Sdiek1_RS07120	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Sdiek1_RS07135	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Sdiek1_RS07140	COG1338	Plays a role in the flagellum-specific transport system
Sdiek1_RS07145	COG0676	glucose-6-phosphate 1-epimerase activity
Sdiek1_RS07150	COG2249	NAD(P)H dehydrogenase (quinone) activity
Sdiek1_RS07165	COG3174	membrane
Sdiek1_RS07170	COG1032	radical SAM domain protein
Sdiek1_RS07175	COG0166	Belongs to the GPI family
Sdiek1_RS07195	COG3259	Nickel-dependent hydrogenase
Sdiek1_RS07200	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Sdiek1_RS07205	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Sdiek1_RS07210	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
Sdiek1_RS07215	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Sdiek1_RS07220	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Sdiek1_RS07225	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Sdiek1_RS07240	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Sdiek1_RS07245	COG0298	carbon dioxide binding
Sdiek1_RS07250	COG0409	Hydrogenase expression formation protein
Sdiek1_RS07255	COG0309	Hydrogenase expression formation protein (HypE)
Sdiek1_RS07260	COG0375	protein maturation
Sdiek1_RS07265	COG1247	-acetyltransferase
Sdiek1_RS07270	COG0546	phosphoglycolate phosphatase activity
Sdiek1_RS07290	COG0039	L-malate dehydrogenase activity
Sdiek1_RS07300	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Sdiek1_RS07310	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Sdiek1_RS07310	COG0674	pyruvate-flavodoxin oxidoreductase activity
Sdiek1_RS07315	COG3962	Belongs to the TPP enzyme family
Sdiek1_RS07340	COG4565	transcriptional regulatory protein
Sdiek1_RS07360	COG0114	fumarate hydratase activity
Sdiek1_RS07390	COG0842	Transport permease protein
Sdiek1_RS07420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Sdiek1_RS07425	COG0750	zinc metalloprotease
Sdiek1_RS07430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Sdiek1_RS07435	COG1028	Short-chain dehydrogenase reductase Sdr
Sdiek1_RS07440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Sdiek1_RS07450	COG0167	dihydroorotate dehydrogenase activity
Sdiek1_RS07455	COG1132	(ABC) transporter
Sdiek1_RS07460	COG0215	cysteine-tRNA ligase activity
Sdiek1_RS07475	COG0632	four-way junction helicase activity
Sdiek1_RS07480	COG1181	Belongs to the D-alanine--D-alanine ligase family
Sdiek1_RS07495	COG1254	Belongs to the acylphosphatase family
Sdiek1_RS07500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Sdiek1_RS07505	COG0857	belongs to the CobB CobQ family
Sdiek1_RS07505	COG0280	phosphate acetyltransferase
Sdiek1_RS07510	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Sdiek1_RS07515	COG1610	YqeY-like protein
Sdiek1_RS07535	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Sdiek1_RS07580	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Sdiek1_RS07585	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Sdiek1_RS07600	COG0137	argininosuccinate synthase activity
Sdiek1_RS07605	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Sdiek1_RS07610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Sdiek1_RS07615	COG0802	atpase or kinase
Sdiek1_RS07620	COG1137	ATPase activity
Sdiek1_RS07625	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Sdiek1_RS07645	COG0419	ATPase involved in DNA repair
Sdiek1_RS07655	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
Sdiek1_RS07740	COG1053	succinate dehydrogenase
Sdiek1_RS07805	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS07815	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_RS07825	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Sdiek1_RS07835	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
Sdiek1_RS07845	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Sdiek1_RS07855	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Sdiek1_RS07870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Sdiek1_RS07875	COG1120	ATPase activity
Sdiek1_RS07890	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Sdiek1_RS07935	COG1132	(ABC) transporter
Sdiek1_RS07940	COG1797	cobyrinic acid a,c-diamide synthase activity
Sdiek1_RS07955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Sdiek1_RS07955	COG1648	precorrin-2 dehydrogenase activity
Sdiek1_RS07960	COG1309	transcriptional regulator
Sdiek1_RS08065	COG0582	viral genome integration into host DNA
Sdiek1_RS08080	COG0776	regulation of translation
Sdiek1_RS08095	COG1674	ftsk spoiiie
Sdiek1_RS08095	COG1196	nuclear chromosome segregation
Sdiek1_RS08100	COG1049	propionate catabolic process, 2-methylcitrate cycle
Sdiek1_RS08105	COG1047	Peptidyl-prolyl cis-trans
Sdiek1_RS08110	COG0574	Belongs to the PEP-utilizing enzyme family
Sdiek1_RS08110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Sdiek1_RS08115	COG3713	MltA-interacting MipA family protein
Sdiek1_RS08125	COG2814	Major facilitator Superfamily
Sdiek1_RS08145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Sdiek1_RS08150	COG0840	transmembrane signaling receptor activity
Sdiek1_RS08155	COG1832	CoA-binding protein
Sdiek1_RS08160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Sdiek1_RS08170	COG1126	abc transporter atp-binding protein
Sdiek1_RS08175	COG0765	amino acid transport
Sdiek1_RS08180	COG4597	amino acid ABC transporter
Sdiek1_RS08185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Sdiek1_RS08190	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Sdiek1_RS08200	COG0586	Pfam SNARE associated Golgi protein
Sdiek1_RS08205	COG1136	(ABC) transporter
Sdiek1_RS08205	COG0577	efflux transmembrane transporter activity
Sdiek1_RS08210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Sdiek1_RS08235	COG0727	PFAM Uncharacterised protein family (UPF0153)
Sdiek1_RS08245	COG0134	indole-3-glycerol-phosphate synthase activity
Sdiek1_RS08255	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Sdiek1_RS08260	COG1122	ATPase activity
Sdiek1_RS08275	COG0310	cobalt ion transport
Sdiek1_RS08280	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Sdiek1_RS08285	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Sdiek1_RS08300	COG0446	pyridine nucleotide-disulphide oxidoreductase
Sdiek1_RS08315	COG0028	Belongs to the TPP enzyme family
Sdiek1_RS08320	COG0440	acetolactate synthase activity
Sdiek1_RS08325	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Sdiek1_RS08335	COG0493	'glutamate synthase
Sdiek1_RS08345	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Sdiek1_RS08375	COG1045	serine acetyltransferase
Sdiek1_RS08380	COG1166	arginine decarboxylase activity
Sdiek1_RS08385	COG0124	histidyl-tRNA synthetase
Sdiek1_RS08400	COG0163	prenyltransferase activity
Sdiek1_RS08420	COG0303	'Molybdopterin
Sdiek1_RS08425	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Sdiek1_RS08440	COG1691	(AIR) carboxylase
Sdiek1_RS08445	COG1606	tRNA processing
Sdiek1_RS08450	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Sdiek1_RS08460	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Sdiek1_RS08460	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Sdiek1_RS08480	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS08495	COG0588	phosphoglycerate mutase activity
Sdiek1_RS08505	COG0582	viral genome integration into host DNA
Sdiek1_RS08510	COG0343	queuine tRNA-ribosyltransferase activity
Sdiek1_RS08530	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Sdiek1_RS08535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Sdiek1_RS08555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Sdiek1_RS08560	COG1187	pseudouridine synthase activity
Sdiek1_RS08570	COG0028	Belongs to the TPP enzyme family
Sdiek1_RS08600	COG1309	transcriptional regulator
Sdiek1_RS08640	COG3290	protein histidine kinase activity
Sdiek1_RS08640	COG0840	transmembrane signaling receptor activity
Sdiek1_RS08645	COG1592	Rubrerythrin
Sdiek1_RS08655	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Sdiek1_RS08660	COG0181	hydroxymethylbilane synthase activity
Sdiek1_RS08675	COG0442	prolyl-tRNA aminoacylation
Sdiek1_RS08680	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Sdiek1_RS08685	COG0142	geranyltranstransferase activity
Sdiek1_RS08705	COG1959	2 iron, 2 sulfur cluster binding
Sdiek1_RS08715	COG3706	GGDEF domain
Sdiek1_RS08720	COG0525	valine-tRNA ligase activity
Sdiek1_RS08725	COG0521	Mo-molybdopterin cofactor biosynthetic process
Sdiek1_RS08730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Sdiek1_RS08735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Sdiek1_RS08750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Sdiek1_RS08755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Sdiek1_RS08765	COG2195	Cleaves the N-terminal amino acid of tripeptides
Sdiek1_RS08775	COG0500	methyltransferase
Sdiek1_RS08790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Sdiek1_RS08795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Sdiek1_RS08800	COG1663	tetraacyldisaccharide 4'-kinase activity
Sdiek1_RS08805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Sdiek1_RS08810	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Sdiek1_RS08815	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Sdiek1_RS08830	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Sdiek1_RS08840	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Sdiek1_RS08845	COG1420	regulation of RNA biosynthetic process
Sdiek1_RS08855	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Sdiek1_RS08860	COG1959	2 iron, 2 sulfur cluster binding
Sdiek1_RS08865	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Sdiek1_RS08870	COG2404	hydrolase activity, acting on ester bonds
Sdiek1_RS08880	COG2226	methyltransferase
Sdiek1_RS08890	COG0196	riboflavin kinase activity
Sdiek1_RS08895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Sdiek1_RS08900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Sdiek1_RS08905	COG0730	response to heat
Sdiek1_RS08915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Sdiek1_RS08930	COG0527	aspartate kinase activity
Sdiek1_RS08935	COG0494	nUDIX hydrolase
Sdiek1_RS08940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Sdiek1_RS08950	COG0789	Transcriptional regulator
Sdiek1_RS08965	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS08970	COG0642	Histidine kinase
Sdiek1_RS08985	COG0653	protein targeting
Sdiek1_RS09000	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Sdiek1_RS09005	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Sdiek1_RS09020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Sdiek1_RS09025	COG0594	ribonuclease P activity
Sdiek1_RS09030	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Sdiek1_RS09045	COG4865	methylaspartate mutase activity
Sdiek1_RS09060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Sdiek1_RS09075	COG0542	response to heat
Sdiek1_RS09085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Sdiek1_RS09090	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Sdiek1_RS09095	COG0047	phosphoribosylformylglycinamidine synthase activity
Sdiek1_RS09105	COG0204	Acyl-transferase
Sdiek1_RS09110	COG0326	Molecular chaperone. Has ATPase activity
Sdiek1_RS09120	COG1331	Highly conserved protein containing a thioredoxin domain
Sdiek1_RS09125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Sdiek1_RS09165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Sdiek1_RS09180	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Sdiek1_RS09190	COG2608	mercury ion transmembrane transporter activity
Sdiek1_RS09195	COG2217	Heavy metal translocating P-type atpase
Sdiek1_RS09200	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Sdiek1_RS09225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Sdiek1_RS09235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Sdiek1_RS09245	COG2890	protein-(glutamine-N5) methyltransferase activity
Sdiek1_RS09245	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Sdiek1_RS09260	COG0488	(ABC) transporter
Sdiek1_RS09265	COG0840	transmembrane signaling receptor activity
Sdiek1_RS09275	COG2151	metal-sulfur cluster biosynthetic enzyme
Sdiek1_RS09290	COG0138	bifunctional purine biosynthesis protein purh
Sdiek1_RS09295	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Sdiek1_RS09305	COG1607	acyl-coa hydrolase
Sdiek1_RS09310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Sdiek1_RS09315	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Sdiek1_RS09340	COG1694	Mazg nucleotide pyrophosphohydrolase
Sdiek1_RS09355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Sdiek1_RS09360	COG0805	protein transport
Sdiek1_RS09365	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Sdiek1_RS09400	COG3437	response regulator, receiver
Sdiek1_RS09405	COG2205	protein histidine kinase activity
Sdiek1_RS09405	COG3437	response regulator, receiver
Sdiek1_RS09405	COG3850	Histidine kinase
Sdiek1_RS09405	COG4999	Histidine kinase
Sdiek1_RS09410	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Sdiek1_RS09430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Sdiek1_RS09435	COG0569	domain protein
Sdiek1_RS09440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Sdiek1_RS09455	COG2068	MobA-Related Protein
Sdiek1_RS09465	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Sdiek1_RS09470	COG0535	radical SAM domain protein
Sdiek1_RS09500	COG2198	Histidine kinase
Sdiek1_RS09500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Sdiek1_RS09500	COG2205	protein histidine kinase activity
Sdiek1_RS09500	COG0784	Response regulator, receiver
Sdiek1_RS09510	COG0668	transmembrane transport
Sdiek1_RS09525	COG4263	nitrous-oxide reductase activity
Sdiek1_RS09550	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Sdiek1_RS09560	COG0646	methionine synthase
Sdiek1_RS09560	COG1410	methionine synthase
Sdiek1_RS09575	COG0840	transmembrane signaling receptor activity
Sdiek1_RS09580	COG1280	lysine exporter protein (LysE YggA)
Sdiek1_RS09600	COG0004	ammonium transporteR
Sdiek1_RS09605	COG0347	Belongs to the P(II) protein family
Sdiek1_RS09640	COG0288	reversible hydration of carbon dioxide
Sdiek1_RS09645	COG3123	guanosine phosphorylase activity
Sdiek1_RS09655	COG2081	HI0933 family
Sdiek1_RS09665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Sdiek1_RS09670	COG0788	formyltetrahydrofolate deformylase activity
Sdiek1_RS09675	COG0617	tRNA 3'-terminal CCA addition
Sdiek1_RS09690	COG0473	3-isopropylmalate dehydrogenase activity
Sdiek1_RS09695	COG0066	3-isopropylmalate dehydratase activity
Sdiek1_RS09720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Sdiek1_RS09730	COG0708	Exodeoxyribonuclease III
Sdiek1_RS09745	COG2816	NAD+ diphosphatase activity
Sdiek1_RS09750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Sdiek1_RS09755	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Sdiek1_RS09775	COG0840	transmembrane signaling receptor activity
Sdiek1_RS09775	COG3290	protein histidine kinase activity
Sdiek1_RS09780	COG4977	sequence-specific DNA binding
Sdiek1_RS09785	COG0431	NADPH-dependent FMN reductase
Sdiek1_RS09790	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Sdiek1_RS09800	COG3706	GGDEF domain
Sdiek1_RS09810	COG4895	conserved protein (DUF2196)
Sdiek1_RS09850	COG0513	Belongs to the DEAD box helicase family
Sdiek1_RS09865	COG0642	Histidine kinase
Sdiek1_RS09870	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS09905	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Sdiek1_RS09910	COG0372	Belongs to the citrate synthase family
Sdiek1_RS09915	COG2079	MmgE PrpD family protein
Sdiek1_RS09925	COG2824	Alkylphosphonate utilization operon protein PhnA
Sdiek1_RS09935	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Sdiek1_RS09945	COG4786	Flagellar basal body rod
Sdiek1_RS09960	COG1733	regulation of RNA biosynthetic process
Sdiek1_RS09975	COG1121	(ABC) transporter
Sdiek1_RS09980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Sdiek1_RS09995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Sdiek1_RS10000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Sdiek1_RS10005	COG3162	membrane
Sdiek1_RS10010	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS10015	COG0642	Histidine kinase
Sdiek1_RS10030	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Sdiek1_RS10035	COG1918	ferrous iron import across plasma membrane
Sdiek1_RS10060	COG3585	molybdate ion transport
Sdiek1_RS10070	COG0598	Magnesium transport protein CorA
Sdiek1_RS10075	COG0739	heme binding
Sdiek1_RS10085	COG0277	FAD linked oxidase domain protein
Sdiek1_RS10090	COG1295	ribonuclease BN
Sdiek1_RS10100	COG0305	Participates in initiation and elongation during chromosome replication
Sdiek1_RS10105	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Sdiek1_RS10110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Sdiek1_RS10115	COG2165	general secretion pathway protein
Sdiek1_RS10135	COG0556	nucleotide-excision repair
Sdiek1_RS10145	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Sdiek1_RS10150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Sdiek1_RS10155	COG2176	DNA-directed DNA polymerase activity
Sdiek1_RS10160	COG0135	phosphoribosylanthranilate isomerase activity
Sdiek1_RS10165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Sdiek1_RS10175	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Sdiek1_RS10190	COG1692	metallophosphoesterase
Sdiek1_RS10195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Sdiek1_RS10205	COG0739	heme binding
Sdiek1_RS10210	COG0285	dihydrofolate synthase activity
Sdiek1_RS10225	COG0495	leucyl-tRNA aminoacylation
Sdiek1_RS10230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Sdiek1_RS10235	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Sdiek1_RS10240	COG1862	Preprotein translocase
Sdiek1_RS10245	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Sdiek1_RS10250	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Sdiek1_RS10260	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Sdiek1_RS10270	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Sdiek1_RS10280	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Sdiek1_RS10285	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Sdiek1_RS10290	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Sdiek1_RS10295	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Sdiek1_RS10300	COG0210	DNA helicase
Sdiek1_RS10330	COG0540	Belongs to the ATCase OTCase family
Sdiek1_RS10340	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Sdiek1_RS10350	COG2207	Transcriptional regulator
Sdiek1_RS10350	COG3708	Transcriptional regulator
Sdiek1_RS10370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Sdiek1_RS10385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Sdiek1_RS10390	COG0564	pseudouridine synthase activity
Sdiek1_RS10395	COG1519	Transferase
Sdiek1_RS10405	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Sdiek1_RS10410	COG0752	glycyl-tRNA synthetase alpha subunit
Sdiek1_RS10420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Sdiek1_RS10425	COG0826	peptidase U32
Sdiek1_RS10435	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Sdiek1_RS10440	COG0174	glutamine synthetase
Sdiek1_RS10450	COG4172	Belongs to the ABC transporter superfamily
Sdiek1_RS10455	COG0156	8-amino-7-oxononanoate synthase activity
Sdiek1_RS10460	COG0424	maF-like protein
Sdiek1_RS10470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Sdiek1_RS10490	COG1028	Short-chain dehydrogenase reductase Sdr
Sdiek1_RS10500	COG0673	inositol 2-dehydrogenase activity
Sdiek1_RS10505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Sdiek1_RS10510	COG0768	penicillin binding
Sdiek1_RS10520	COG1558	bacterial-type flagellum-dependent cell motility
Sdiek1_RS10525	COG1815	bacterial-type flagellum-dependent cell motility
Sdiek1_RS10530	COG0772	Belongs to the SEDS family
Sdiek1_RS10550	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Sdiek1_RS10605	COG0512	Glutamine amidotransferase of anthranilate synthase
Sdiek1_RS10610	COG2814	Major facilitator Superfamily
Sdiek1_RS10620	COG0640	Transcriptional regulator
Sdiek1_RS10630	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
Sdiek1_RS10640	COG2301	Belongs to the HpcH HpaI aldolase family
Sdiek1_RS10645	COG3052	prosthetic group binding
Sdiek1_RS10650	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
Sdiek1_RS10660	COG2814	Major facilitator Superfamily
Sdiek1_RS10670	COG2252	PERMEase
Sdiek1_RS10675	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Sdiek1_RS10680	COG0133	tryptophan synthase activity
Sdiek1_RS10690	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Sdiek1_RS10700	COG3706	GGDEF domain
Sdiek1_RS10720	COG2202	Pas domain
Sdiek1_RS10720	COG2200	EAL domain
Sdiek1_RS10720	COG2199	diguanylate cyclase activity
Sdiek1_RS10730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Sdiek1_RS10750	COG0488	(ABC) transporter
Sdiek1_RS10755	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_RS10760	COG0651	ATP synthesis coupled electron transport
Sdiek1_RS10765	COG0650	Formate hydrogenlyase subunit 4
Sdiek1_RS10770	COG4237	Hydrogenase 4 membrane
Sdiek1_RS10780	COG3261	NADH dehydrogenase
Sdiek1_RS10780	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
Sdiek1_RS10790	COG3260	NADH ubiquinone oxidoreductase 20
Sdiek1_RS10825	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Sdiek1_RS10840	COG2171	N-acyltransferase activity
Sdiek1_RS10845	COG0489	protein tyrosine kinase activity
Sdiek1_RS10850	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Sdiek1_RS10850	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Sdiek1_RS10860	COG2046	Belongs to the sulfate adenylyltransferase family
Sdiek1_RS10870	COG2353	YceI-like domain
Sdiek1_RS10875	COG1739	Uncharacterized protein family UPF0029
Sdiek1_RS10880	COG0157	Belongs to the NadC ModD family
Sdiek1_RS10885	COG4149	molybdate abc transporter
Sdiek1_RS10895	COG3842	ATPase activity
Sdiek1_RS10920	COG1686	Belongs to the peptidase S11 family
Sdiek1_RS10925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Sdiek1_RS10930	COG0577	efflux transmembrane transporter activity
Sdiek1_RS10930	COG1136	(ABC) transporter
Sdiek1_RS10935	COG1136	(ABC) transporter
Sdiek1_RS10960	COG0668	transmembrane transport
Sdiek1_RS10970	COG3300	MHYT domain
Sdiek1_RS10970	COG5001	Diguanylate cyclase
Sdiek1_RS11065	COG1450	Type ii and iii secretion system protein
Sdiek1_RS11125	COG0284	orotidine-5'-phosphate decarboxylase activity
Sdiek1_RS11130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Sdiek1_RS11145	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Sdiek1_RS11150	COG0697	spore germination
Sdiek1_RS11155	COG0668	transmembrane transport
Sdiek1_RS11160	COG1160	GTP binding
Sdiek1_RS11185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Sdiek1_RS11190	COG1183	phosphatidylcholine synthase activity
Sdiek1_RS11200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Sdiek1_RS11205	COG2264	protein methyltransferase activity
Sdiek1_RS11210	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS11215	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Sdiek1_RS11220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Sdiek1_RS11240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Sdiek1_RS11280	COG0028	Belongs to the TPP enzyme family
Sdiek1_RS11290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Sdiek1_RS11305	COG1793	dna ligase
Sdiek1_RS11315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Sdiek1_RS11320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Sdiek1_RS11345	COG0859	PFAM glycosyl transferase family 9
Sdiek1_RS11365	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Sdiek1_RS11370	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Sdiek1_RS11370	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Sdiek1_RS11380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Sdiek1_RS11400	COG2217	Heavy metal translocating P-type atpase
Sdiek1_RS11410	COG0697	spore germination
Sdiek1_RS11435	COG1496	oxidoreductase activity
Sdiek1_RS11445	COG0840	transmembrane signaling receptor activity
Sdiek1_RS11450	COG1984	allophanate hydrolase subunit 2
Sdiek1_RS11460	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Sdiek1_RS11465	COG0445	tRNA wobble uridine modification
Sdiek1_RS11470	COG0723	plastoquinol--plastocyanin reductase activity
Sdiek1_RS11475	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Sdiek1_RS11480	COG2857	Cytochrome c1
Sdiek1_RS11490	COG0825	malonyl-CoA metabolic process
Sdiek1_RS11495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Sdiek1_RS11500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Sdiek1_RS11510	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Sdiek1_RS11515	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Sdiek1_RS11520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Sdiek1_RS11530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Sdiek1_RS11540	COG0297	glycogen (starch) synthase activity
Sdiek1_RS11550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Sdiek1_RS11555	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Sdiek1_RS11600	COG0572	uridine kinase
Sdiek1_RS11625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Sdiek1_RS11645	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Sdiek1_RS11645	COG0662	Cupin 2, conserved barrel domain protein
Sdiek1_RS11650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Sdiek1_RS11675	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS11690	COG0398	Pfam SNARE associated Golgi protein
Sdiek1_RS11695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Sdiek1_RS11715	COG0390	transport system, permease component
Sdiek1_RS11720	COG0439	Biotin carboxylase
Sdiek1_RS11735	COG0513	Belongs to the DEAD box helicase family
Sdiek1_RS11740	COG1671	Belongs to the UPF0178 family
Sdiek1_RS11745	COG0667	Aldo Keto reductase
Sdiek1_RS11750	COG2814	Major facilitator Superfamily
Sdiek1_RS11755	COG2207	Transcriptional regulator
Sdiek1_RS11775	COG0573	inorganic phosphate transmembrane transporter activity
Sdiek1_RS11785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Sdiek1_RS11790	COG3290	protein histidine kinase activity
Sdiek1_RS11790	COG0840	transmembrane signaling receptor activity
Sdiek1_RS11795	COG3384	dioxygenase
Sdiek1_RS11800	COG0840	transmembrane signaling receptor activity
Sdiek1_RS11815	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS11825	COG1607	acyl-coa hydrolase
Sdiek1_RS11850	COG1733	regulation of RNA biosynthetic process
Sdiek1_RS11855	COG2249	NAD(P)H dehydrogenase (quinone) activity
Sdiek1_RS11860	COG3852	Histidine kinase
Sdiek1_RS11865	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Sdiek1_RS11870	COG0602	queuosine metabolic process
Sdiek1_RS11910	COG2814	Major facilitator Superfamily
Sdiek1_RS11915	COG0477	Major facilitator Superfamily
Sdiek1_RS11925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Sdiek1_RS11950	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Sdiek1_RS11980	COG1013	pyruvate-flavodoxin oxidoreductase activity
Sdiek1_RS11980	COG0674	pyruvate-flavodoxin oxidoreductase activity
Sdiek1_RS11980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Sdiek1_RS11980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Sdiek1_RS11990	COG0471	metal ion transport
Sdiek1_RS12000	COG0668	transmembrane transport
Sdiek1_RS12005	COG2885	chlorophyll binding
Sdiek1_RS12005	COG3047	cAMP biosynthetic process
Sdiek1_RS12015	COG1881	PFAM PEBP family protein
Sdiek1_RS12020	COG2207	Transcriptional regulator
Sdiek1_RS12025	COG0519	Catalyzes the synthesis of GMP from XMP
Sdiek1_RS12055	COG0038	chloride channel
Sdiek1_RS12060	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Sdiek1_RS12070	COG0500	methyltransferase
Sdiek1_RS12080	COG1324	tolerance protein
Sdiek1_RS12085	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Sdiek1_RS12090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Sdiek1_RS12135	COG3278	Belongs to the heme-copper respiratory oxidase family
Sdiek1_RS12140	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS12155	COG0505	Belongs to the CarA family
Sdiek1_RS12175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Sdiek1_RS12180	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Sdiek1_RS12185	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Sdiek1_RS12195	COG0546	phosphoglycolate phosphatase activity
Sdiek1_RS12215	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Sdiek1_RS12220	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Sdiek1_RS12225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Sdiek1_RS12240	COG0203	ribosomal protein L17
Sdiek1_RS12250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Sdiek1_RS12255	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Sdiek1_RS12260	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Sdiek1_RS12265	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Sdiek1_RS12275	COG0024	Methionine aminopeptidase
Sdiek1_RS12280	COG0201	protein transport
Sdiek1_RS12285	COG0200	Binds to the 23S rRNA
Sdiek1_RS12290	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Sdiek1_RS12295	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Sdiek1_RS12300	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Sdiek1_RS12305	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Sdiek1_RS12310	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Sdiek1_RS12320	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Sdiek1_RS12325	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Sdiek1_RS12330	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Sdiek1_RS12335	COG0255	Belongs to the universal ribosomal protein uL29 family
Sdiek1_RS12340	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Sdiek1_RS12345	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Sdiek1_RS12355	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Sdiek1_RS12360	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Sdiek1_RS12365	COG0089	rRNA binding
Sdiek1_RS12370	COG0088	Forms part of the polypeptide exit tunnel
Sdiek1_RS12375	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Sdiek1_RS12380	COG0051	transcription antitermination factor activity, RNA binding
Sdiek1_RS12400	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Sdiek1_RS12410	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Sdiek1_RS12415	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Sdiek1_RS12420	COG0571	ribonuclease III activity
Sdiek1_RS12425	COG0328	RNA-DNA hybrid ribonuclease activity
Sdiek1_RS12435	COG0358	DNA primase activity
Sdiek1_RS12440	COG0137	argininosuccinate synthase activity
Sdiek1_RS12445	COG2201	protein-glutamate methylesterase activity
Sdiek1_RS12460	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS12465	COG2205	protein histidine kinase activity
Sdiek1_RS12470	COG2201	protein-glutamate methylesterase activity
Sdiek1_RS12475	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Sdiek1_RS12480	COG5002	protein histidine kinase activity
Sdiek1_RS12490	COG2198	Histidine kinase
Sdiek1_RS12490	COG0643	Histidine kinase
Sdiek1_RS12500	COG0840	transmembrane signaling receptor activity
Sdiek1_RS12505	COG0835	chemotaxis
Sdiek1_RS12510	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS12545	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Sdiek1_RS12550	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Sdiek1_RS12570	COG1280	lysine exporter protein (LysE YggA)
Sdiek1_RS12575	COG1090	epimerase
Sdiek1_RS12590	COG1136	(ABC) transporter
Sdiek1_RS12615	COG2199	diguanylate cyclase activity
Sdiek1_RS12620	COG2962	Rard protein
Sdiek1_RS12625	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS12630	COG5002	protein histidine kinase activity
Sdiek1_RS12635	COG2194	sulfuric ester hydrolase activity
Sdiek1_RS12645	COG2200	EAL domain
Sdiek1_RS12660	COG1968	undecaprenyl-diphosphatase activity
Sdiek1_RS12665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Sdiek1_RS12670	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
Sdiek1_RS12690	COG1027	Aspartate ammonia-lyase
Sdiek1_RS12695	COG1027	Aspartate ammonia-lyase
Sdiek1_RS12705	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Sdiek1_RS12710	COG0252	asparaginase activity
Sdiek1_RS12715	COG4191	Histidine kinase
Sdiek1_RS12720	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS12730	COG0714	Associated with various cellular activities
Sdiek1_RS12785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Sdiek1_RS12790	COG0765	amino acid transport
Sdiek1_RS12860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Sdiek1_RS12895	COG0709	Synthesizes selenophosphate from selenide and ATP
Sdiek1_RS12900	COG0425	Belongs to the sulfur carrier protein TusA family
Sdiek1_RS12910	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Sdiek1_RS12920	COG5002	protein histidine kinase activity
Sdiek1_RS12920	COG5001	Diguanylate cyclase
Sdiek1_RS12920	COG3447	MASE1 domain protein
Sdiek1_RS12930	COG2814	Major facilitator Superfamily
Sdiek1_RS12950	COG3839	Belongs to the ABC transporter superfamily
Sdiek1_RS12955	COG4662	Binding-protein-dependent transport system inner membrane component
Sdiek1_RS12960	COG2998	abc-type tungstate transport system, permease component
Sdiek1_RS12970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Sdiek1_RS12980	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_RS13005	COG0243	molybdopterin cofactor binding
Sdiek1_RS13005	COG3383	formate dehydrogenase (NAD+) activity
Sdiek1_RS13020	COG1120	ATPase activity
Sdiek1_RS13025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Sdiek1_RS13030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Sdiek1_RS13035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Sdiek1_RS13050	COG0848	biopolymer transport protein
Sdiek1_RS13055	COG0811	peptide transport
Sdiek1_RS13080	COG0500	methyltransferase
Sdiek1_RS13090	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Sdiek1_RS13095	COG4208	sulfate ABC transporter
Sdiek1_RS13100	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Sdiek1_RS13105	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Sdiek1_RS13110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Sdiek1_RS13150	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_RS13180	COG2205	protein histidine kinase activity
Sdiek1_RS13190	COG1921	L-seryl-tRNASec selenium transferase activity
Sdiek1_RS13215	COG1741	Belongs to the pirin family
Sdiek1_RS13250	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS13275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Sdiek1_RS13280	COG0463	Glycosyl transferase, family 2
Sdiek1_RS13290	COG1028	Short-chain dehydrogenase reductase Sdr
Sdiek1_RS13310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Sdiek1_RS13335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Sdiek1_RS13345	COG0513	Belongs to the DEAD box helicase family
Sdiek1_RS13375	COG1305	Transglutaminase-like
Sdiek1_RS13385	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS13420	COG3842	ATPase activity
Sdiek1_RS13425	COG2011	ABC-type metal ion transport system permease component
Sdiek1_RS13435	COG0642	Histidine kinase
Sdiek1_RS13440	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS13455	COG2205	protein histidine kinase activity
Sdiek1_RS13460	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Sdiek1_RS13465	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Sdiek1_RS13470	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Sdiek1_RS13480	COG0840	transmembrane signaling receptor activity
Sdiek1_RS13485	COG0300	oxidoreductase activity
Sdiek1_RS13500	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Sdiek1_RS13510	COG2814	Major facilitator Superfamily
Sdiek1_RS13515	COG1238	metal cluster binding
Sdiek1_RS13530	COG0471	metal ion transport
Sdiek1_RS13545	COG0303	'Molybdopterin
Sdiek1_RS13550	COG0314	molybdopterin synthase activity
Sdiek1_RS13570	COG1157	protein secretion by the type III secretion system
Sdiek1_RS13575	COG0302	gtp cyclohydrolase
Sdiek1_RS13580	COG0544	peptidyl-prolyl cis-trans isomerase activity
Sdiek1_RS13585	COG0740	serine-type endopeptidase activity
Sdiek1_RS13600	COG0606	chelatase, subunit chli
Sdiek1_RS13605	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Sdiek1_RS13605	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Sdiek1_RS13615	COG2022	thiamine diphosphate biosynthetic process
Sdiek1_RS13665	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS13670	COG0642	Histidine kinase
Sdiek1_RS13680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Sdiek1_RS13685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Sdiek1_RS13700	COG0463	Glycosyl transferase, family 2
Sdiek1_RS13725	COG0671	phosphoesterase, PA-phosphatase related
Sdiek1_RS13735	COG1012	belongs to the aldehyde dehydrogenase family
Sdiek1_RS13750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Sdiek1_RS13770	COG0840	transmembrane signaling receptor activity
Sdiek1_RS13780	COG3300	MHYT domain
Sdiek1_RS13780	COG5001	Diguanylate cyclase
Sdiek1_RS13805	COG0842	Transport permease protein
Sdiek1_RS13810	COG0842	Transport permease protein
Sdiek1_RS13815	COG1131	(ABC) transporter
Sdiek1_RS13820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Sdiek1_RS13825	COG1309	transcriptional regulator
Sdiek1_RS13830	COG0778	Nitroreductase
Sdiek1_RS13865	COG1136	(ABC) transporter
Sdiek1_RS13915	COG0454	-acetyltransferase
Sdiek1_RS13920	COG0431	NADPH-dependent FMN reductase
Sdiek1_RS13930	COG4221	oxidoreductase activity
Sdiek1_RS13935	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Sdiek1_RS13940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Sdiek1_RS13980	COG0745	RESPONSE REGULATOR receiver
Sdiek1_RS13985	COG0642	Histidine kinase
Sdiek1_RS14000	COG1840	ABC-type Fe3 transport system, periplasmic component
Sdiek1_RS14010	COG0175	sulfate reduction
Sdiek1_RS14015	COG0175	sulfate reduction
Sdiek1_RS14020	COG2895	sulfate adenylyltransferase (ATP) activity
Sdiek1_RS14030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Sdiek1_RS14040	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Sdiek1_RS14045	COG1648	precorrin-2 dehydrogenase activity
Sdiek1_RS14045	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Sdiek1_RS14050	COG2873	o-acetylhomoserine
Sdiek1_RS14060	COG0482	sulfurtransferase activity
Sdiek1_RS14080	COG3706	GGDEF domain
Sdiek1_RS14090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Sdiek1_RS14100	COG0861	Integral membrane protein TerC family
Sdiek1_RS14105	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Sdiek1_RS14110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Sdiek1_RS14115	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Sdiek1_RS14120	COG0281	malic enzyme
Sdiek1_RS14120	COG0280	phosphate acetyltransferase
Sdiek1_RS14125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Sdiek1_RS14135	COG0439	Biotin carboxylase
Sdiek1_RS14140	COG0511	ligase activity, forming carbon-carbon bonds
Sdiek1_RS14145	COG0717	Belongs to the dCTP deaminase family
Sdiek1_RS14170	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Sdiek1_RS14175	COG1073	alpha beta
Sdiek1_RS14190	COG1086	Polysaccharide biosynthesis protein
Sdiek1_RS14195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Sdiek1_RS14200	COG1083	cytidylyl-transferase
Sdiek1_RS14210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Sdiek1_RS14215	COG2089	acid synthase
Sdiek1_RS14230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Sdiek1_RS14235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Sdiek1_RS14245	COG0154	amidase activity
Sdiek1_RS14270	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Sdiek1_RS14275	COG0372	Belongs to the citrate synthase family
Sdiek1_RS14295	COG0148	phosphopyruvate hydratase activity
Sdiek1_RS14300	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Sdiek1_RS14305	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Sdiek1_RS14315	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Sdiek1_RS14330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Sdiek1_RS14360	COG1408	metallophosphoesterase
Sdiek1_RS14365	COG1115	amino acid carrier protein
Sdiek1_RS14370	COG2233	PERMEase
Sdiek1_RS14375	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Sdiek1_RS14380	COG0575	Belongs to the CDS family
Sdiek1_RS14390	COG1293	RNA-binding protein homologous to eukaryotic snRNP
Sdiek1_RS14395	COG1929	Belongs to the glycerate kinase type-1 family
Sdiek1_RS14400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Sdiek1_RS14415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Sdiek1_RS14425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Sdiek1_RS14430	COG0746	molybdenum cofactor guanylyltransferase activity
Sdiek1_RS14460	COG0724	RNA recognition motif
Sdiek1_RS14465	COG0315	cyclic pyranopterin monophosphate synthase activity
Sdiek1_RS14470	COG2921	Belongs to the UPF0250 family
Sdiek1_RS14555	COG0670	Belongs to the BI1 family
Sdiek1_RS14605	COG0437	4 iron, 4 sulfur cluster binding
Sdiek1_RS14610	COG0243	molybdopterin cofactor binding
Sdiek1_RS14615	COG4106	trans-aconitate 2-methyltransferase activity
Sdiek1_RS14635	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Sdiek1_RS14640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Sdiek1_RS14650	COG0233	cytoplasmic translational termination
Sdiek1_RS14655	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Sdiek1_RS14680	COG1704	LemA family
Sdiek1_RS14685	COG1217	gtp-binding protein TYPA
Sdiek1_RS14695	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Sdiek1_RS14700	COG1749	Flagellar hook protein flgE
Sdiek1_RS14705	COG1749	Flagellar hook protein flgE
Sdiek1_RS14710	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Sdiek1_RS14715	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group