locus-tag	class	description
FG381_RS00020	ENOG4105C9Q	fumarate hydratase class II
FG381_RS00030	ENOG4105CV8	reductase
FG381_RS00045	ENOG4107EFR	Flavocytochrome c
FG381_RS00055	ENOG4108Z9W	Outer membrane porin
FG381_RS00065	ENOG4105CV8	reductase
FG381_RS00075	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FG381_RS00085	ENOG4105FF2	Type I DHQase
FG381_RS00105	ENOG4108KXV	response regulator
FG381_RS00110	ENOG4105BZU	Histidine kinase
FG381_RS00140	ENOG4105C1G	acyl-Coa dehydrogenase
FG381_RS00145	ENOG4107R0K	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
FG381_RS00160	ENOG4105EMV	Major Facilitator
FG381_RS00165	ENOG4105CV7	Electron transfer flavoprotein
FG381_RS00170	ENOG4105C10	Electron transfer flavoprotein
FG381_RS00175	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
FG381_RS00180	ENOG41090P5	ferredoxin-like protein
FG381_RS00185	ENOG4105CEY	Amp-dependent synthetase and ligase
FG381_RS00190	ENOG4105EMV	Major Facilitator
FG381_RS00195	ENOG4105W4W	Transcriptional regulator
FG381_RS00200	ENOG4107XWB	Zinc finger, swim domain protein
FG381_RS00205	ENOG4105C0D	helicase
FG381_RS00210	ENOG4108RAC	Rubrerythrin
FG381_RS00220	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
FG381_RS00225	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FG381_RS00230	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
FG381_RS00240	ENOG4105DDQ	anthranilate synthase
FG381_RS00280	ENOG4105E2X	shikimate dehydrogenase
FG381_RS00285	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FG381_RS00290	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FG381_RS00295	ENOG4105D49	3-dehydroquinate synthase
FG381_RS00300	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
FG381_RS00305	ENOG4105CA0	peroxidase
FG381_RS00315	ENOG4108MR7	Arylsulfotransferase
FG381_RS00435	ENOG4108WS4	fmn reductase
FG381_RS00450	ENOG4107GFK	fumarate
FG381_RS00455	ENOG4105F87	Dehydratase
FG381_RS00460	ENOG4105DEF	Extracellular solute-binding protein, family 5
FG381_RS00470	ENOG4108KSA	LysR family transcriptional regulator
FG381_RS00475	ENOG4107EFR	Flavocytochrome c
FG381_RS00495	ENOG4105C87	Aminotransferase class I and II
FG381_RS00515	ENOG4105NF4	modulator of drug activity
FG381_RS00540	ENOG4105G2Y	Transcriptional regulator
FG381_RS00545	ENOG4108MR7	Arylsulfotransferase
FG381_RS00565	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
FG381_RS00570	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FG381_RS00575	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FG381_RS00580	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FG381_RS00595	ENOG4105RPH	Inner membrane protein YddG
FG381_RS00615	ENOG4108VJC	ABC transporter, periplasmic molybdate-binding protein
FG381_RS00620	ENOG4108W0P	ABC transporter
FG381_RS00625	ENOG4105EHG	Permease protein
FG381_RS00630	ENOG4105S10	periplasmic binding protein
FG381_RS00635	ENOG4107EFR	Flavocytochrome c
FG381_RS00645	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
FG381_RS00650	ENOG4105D98	threonine synthase
FG381_RS00655	ENOG4105D6E	homoserine dehydrogenase
FG381_RS00660	ENOG4105CFH	Aspartokinase
FG381_RS00665	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FG381_RS00685	ENOG4105EGS	Mechanosensitive ion channel
FG381_RS00720	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
FG381_RS00725	ENOG4107QR9	Iron-sulfur cluster binding protein
FG381_RS00730	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FG381_RS00750	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
FG381_RS00755	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FG381_RS00760	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FG381_RS00765	ENOG4107R0W	ABC transporter
FG381_RS00775	ENOG4105CH2	amidohydrolase
FG381_RS00795	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
FG381_RS00980	ENOG4105F2I	Transposase
FG381_RS00995	ENOG4108TFY	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FG381_RS01000	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FG381_RS01025	ENOG4105X1Q	TOBE domain protein
FG381_RS01030	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FG381_RS01040	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FG381_RS01045	ENOG4105KT5	UmuD protein
FG381_RS01060	ENOG4105DHQ	Histidine kinase
FG381_RS01065	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
FG381_RS01070	ENOG4108Z9W	Outer membrane porin
FG381_RS01105	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FG381_RS01115	ENOG4107QW8	radical SAM domain protein
FG381_RS01135	ENOG4108IPT	Naphthoate synthase
FG381_RS01145	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FG381_RS01155	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
FG381_RS01165	ENOG4108MR7	Arylsulfotransferase
FG381_RS01175	ENOG4108J59	Extracellular solute-binding protein, family 5
FG381_RS01180	ENOG4106PMH	Extracellular solute-binding protein family 3
FG381_RS01190	ENOG4106PMH	Extracellular solute-binding protein family 3
FG381_RS01200	ENOG4105MRR	Transcriptional regulator (By similarity)
FG381_RS01210	ENOG4105KT5	UmuD protein
FG381_RS01255	ENOG4108MR7	Arylsulfotransferase
FG381_RS01270	ENOG4105CHM	Aminotransferase
FG381_RS01275	ENOG4105D0S	secretion protein (HlyD
FG381_RS01280	ENOG4105CJ1	ABC, transporter
FG381_RS01285	ENOG4107QWP	ABC-2 type transporter
FG381_RS01290	ENOG4107QWP	ABC-2 type transporter
FG381_RS01300	ENOG4107SET	aldo keto reductase
FG381_RS01310	ENOG4107SET	aldo keto reductase
FG381_RS01325	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
FG381_RS01330	ENOG4105C0D	helicase
FG381_RS01355	ENOG4107QY8	reductase
FG381_RS01370	ENOG4107QY8	reductase
FG381_RS01375	ENOG4105QAX	Iron-sulfur
FG381_RS01390	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FG381_RS01400	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
FG381_RS01410	ENOG4105TMB	Formate nitrite transporter
FG381_RS01435	ENOG4105DRP	amino acid AbC transporter
FG381_RS01440	ENOG4105CDA	abc transporter atp-binding protein
FG381_RS01445	ENOG4105EAB	amino acid AbC transporter
FG381_RS01455	ENOG4105CB5	ATP-dependent DNA helicase recG
FG381_RS01475	ENOG4107EFR	Flavocytochrome c
FG381_RS01480	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FG381_RS01485	ENOG4106AFQ	Histidine kinase
FG381_RS01500	ENOG4105C94	Transporter
FG381_RS01515	ENOG4105WMR	Protein CrcB homolog
FG381_RS01520	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
FG381_RS01525	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FG381_RS01575	ENOG4105CF7	AraC family transcriptional regulator
FG381_RS01585	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FG381_RS01600	ENOG4105CEM	UPF0597 protein
FG381_RS01605	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FG381_RS01620	ENOG4105K63	Thioredoxin
FG381_RS01680	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
FG381_RS01685	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
FG381_RS01705	ENOG4105ENX	hydrolase
FG381_RS01715	ENOG4107QW4	alcohol dehydrogenase
FG381_RS01720	ENOG4105BZW	Glycerate kinase
FG381_RS01725	ENOG4108UIN	ybak prolyl-trna synthetase associated region
FG381_RS01745	ENOG4108C33	Resolvase
FG381_RS01790	ENOG4107QZ7	Cellulose synthase catalytic subunit
FG381_RS01795	ENOG4107EEX	Cellulose synthase regulator protein
FG381_RS01800	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
FG381_RS01805	ENOG4105EJG	cellulose synthase
FG381_RS01810	ENOG4105BZU	Histidine kinase
FG381_RS01815	ENOG4105E89	ABC transporter
FG381_RS01820	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
FG381_RS01835	ENOG4105D1V	cellulose synthase operon protein YhjU
FG381_RS01860	ENOG4105DRP	amino acid AbC transporter
FG381_RS01865	ENOG4105EAB	amino acid AbC transporter
FG381_RS01870	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FG381_RS01880	ENOG4105C6T	cysteine synthase
FG381_RS01885	ENOG4108IJ6	ABC transporter
FG381_RS01890	ENOG4105ECW	sulfate abc transporter
FG381_RS01895	ENOG4108I5D	sulfate abc transporter
FG381_RS01905	ENOG4105CR8	Transcriptional regulator
FG381_RS01910	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FG381_RS01945	ENOG4108ETV	ABC transporter
FG381_RS01950	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
FG381_RS01990	ENOG4105WWK	YheO domain protein
FG381_RS02000	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
FG381_RS02005	ENOG4105CEE	C4-dicarboxylate transporter
FG381_RS02010	ENOG4105DIJ	Phosphoethanolamine transferase
FG381_RS02025	ENOG4105VCQ	rubredoxin
FG381_RS02040	ENOG4105X9Y	Hydrogenase assembly chaperone hypC hupF
FG381_RS02045	ENOG4108USZ	hydrogenase
FG381_RS02070	ENOG4108YZA	Nitrogen regulatory protein pii
FG381_RS02075	ENOG4105BZU	Histidine kinase
FG381_RS02085	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
FG381_RS02090	ENOG4105HDK	L-asparaginase
FG381_RS02110	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FG381_RS02115	ENOG4108J2R	molybdopterin oxidoreductase
FG381_RS02120	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
FG381_RS02125	ENOG4105CEE	C4-dicarboxylate transporter
FG381_RS02130	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
FG381_RS02140	ENOG41074DU	domain protein
FG381_RS02145	ENOG4108594	Permease of the drug metabolite transporter
FG381_RS02150	ENOG4108RYK	Nad-dependent epimerase dehydratase
FG381_RS02175	ENOG4105CJ1	ABC, transporter
FG381_RS02180	ENOG4107QWP	ABC-2 type transporter
FG381_RS02185	ENOG4107QWP	ABC-2 type transporter
FG381_RS02190	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FG381_RS02205	ENOG4108KB2	LysR family Transcriptional regulator
FG381_RS02235	ENOG4105CEE	C4-dicarboxylate transporter
FG381_RS02240	ENOG4105CH7	arginosuccinase
FG381_RS02260	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FG381_RS02270	ENOG4105CH2	amidohydrolase
FG381_RS02275	ENOG4105C0D	helicase
FG381_RS02280	ENOG4105UYK	outer membrane protein a
FG381_RS02305	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
FG381_RS02310	ENOG4105D1V	cellulose synthase operon protein YhjU
FG381_RS02315	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
FG381_RS02320	ENOG4107EEX	Cellulose synthase regulator protein
FG381_RS02325	ENOG4107QZ7	Cellulose synthase catalytic subunit
FG381_RS02330	ENOG4105C5I	Dehydrogenase
FG381_RS02350	ENOG4105BZU	Histidine kinase
FG381_RS02355	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FG381_RS02375	ENOG4107EFR	Flavocytochrome c
FG381_RS02380	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
FG381_RS02385	ENOG4107EFR	Flavocytochrome c
FG381_RS02390	ENOG4107EFR	Flavocytochrome c
FG381_RS02400	ENOG4107QY8	reductase
FG381_RS02405	ENOG4105D01	(LipO)protein
FG381_RS02425	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FG381_RS02430	ENOG4108Z9W	Outer membrane porin
FG381_RS02440	ENOG4107QK5	Homocysteine s-methyltransferase
FG381_RS02445	ENOG4105D01	(LipO)protein
FG381_RS02450	ENOG4105D01	(LipO)protein
FG381_RS02480	ENOG4105E0Y	RtcB Protein
FG381_RS02485	ENOG4108S2Y	peptide Chain Release factor
FG381_RS02490	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
FG381_RS02495	ENOG4105CGF	Aromatic amino acid aminotransferase
FG381_RS02500	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
FG381_RS02510	ENOG4108YV4	Universal stress protein
FG381_RS02520	ENOG41068KF	Universal stress protein
FG381_RS02540	ENOG4108Z9W	Outer membrane porin
FG381_RS02545	ENOG4108MR7	Arylsulfotransferase
FG381_RS02550	ENOG4107EFR	Flavocytochrome c
FG381_RS02565	ENOG4107GFK	fumarate
FG381_RS02570	ENOG4105DUM	transcriptional regulator, lysR family
FG381_RS02575	ENOG4108P2H	Inner membrane protein YjiG
FG381_RS02580	ENOG41074DU	domain protein
FG381_RS02590	ENOG4108P2H	Inner membrane protein YjiG
FG381_RS02595	ENOG41074DU	domain protein
FG381_RS02615	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FG381_RS02620	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FG381_RS02640	ENOG4105KWW	Biogenesis protein
FG381_RS02645	ENOG4105DA4	cytochrome c-type biogenesis protein
FG381_RS02655	ENOG4105CH2	amidohydrolase
FG381_RS02665	ENOG4105RWS	endonuclease I
FG381_RS02685	ENOG4105C2D	reductase
FG381_RS02690	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FG381_RS02715	ENOG4107EFR	Flavocytochrome c
FG381_RS02720	ENOG4105BZU	Histidine kinase
FG381_RS02735	ENOG41090A1	ferritin
FG381_RS02755	ENOG4105DUM	transcriptional regulator, lysR family
FG381_RS02765	ENOG4105C8Y	Acetylornithine aminotransferase
FG381_RS02770	ENOG4105CH7	arginosuccinase
FG381_RS02775	ENOG4105CAS	nag kinase
FG381_RS02780	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FG381_RS02810	ENOG4108C33	Resolvase
FG381_RS02825	ENOG4105C59	p-type ATPase
FG381_RS02845	ENOG4105XFK	Ferrous iron transport protein A
FG381_RS02850	ENOG4105CE1	Ferrous iron transport protein b
FG381_RS02865	ENOG4105K70	DNA-binding protein
FG381_RS02870	ENOG4105C3S	Mate efflux family protein
FG381_RS02885	ENOG4107EFR	Flavocytochrome c
FG381_RS02890	ENOG4105C59	p-type ATPase
FG381_RS02925	ENOG4105UYK	outer membrane protein a
FG381_RS02930	ENOG4108P8G	outer membrane autotransporter barrel
FG381_RS02950	ENOG4105HDK	L-asparaginase
FG381_RS02970	ENOG4107RB3	L-asparaginase
FG381_RS02980	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FG381_RS02990	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FG381_RS02995	ENOG4108JJB	ABC transporter
FG381_RS03000	ENOG4105C7J	ABC transporter, permease
FG381_RS03010	ENOG4105EMU	Dehydrogenase
FG381_RS03020	ENOG4105FCD	Major Facilitator
FG381_RS03025	ENOG4105CH2	amidohydrolase
FG381_RS03045	ENOG4105Y49	secretion protein, HlyD family
FG381_RS03055	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FG381_RS03070	ENOG4105CUZ	uba thif-type nad fad binding protein
FG381_RS03085	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FG381_RS03110	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FG381_RS03135	ENOG4105C0A	alcohol dehydrogenase
FG381_RS03185	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FG381_RS03190	ENOG4105EN6	Membrane
FG381_RS03195	ENOG4108IJF	Heavy metal efflux pump, CzcA
FG381_RS03200	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
FG381_RS03210	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FG381_RS03235	ENOG4105CH7	arginosuccinase
FG381_RS03250	ENOG4105QAX	Iron-sulfur
FG381_RS03265	ENOG4108TQ9	Histidine kinase
FG381_RS03270	ENOG4105R3P	Inner membrane protein yagU
FG381_RS03295	ENOG4105CEE	C4-dicarboxylate transporter
FG381_RS03320	ENOG4105FAV	ABC, transporter
FG381_RS03325	ENOG4105FDK	ABC transporter
FG381_RS03330	ENOG4105DSE	periplasmic solute binding protein
FG381_RS03340	ENOG4105EAB	amino acid AbC transporter
FG381_RS03345	ENOG4105DRP	amino acid AbC transporter
FG381_RS03360	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
FG381_RS03365	ENOG4105C8N	cysteinyl-tRNA synthetase
FG381_RS03385	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
FG381_RS03390	ENOG4105Z26	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
FG381_RS03410	ENOG4108MR7	Arylsulfotransferase
FG381_RS03415	ENOG4105FR1	rard protein
FG381_RS03425	ENOG4108JQ6	ABC transporter
FG381_RS03430	ENOG4105DEF	Extracellular solute-binding protein, family 5
FG381_RS03435	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FG381_RS03440	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FG381_RS03475	ENOG4105C09	Bile acid
FG381_RS03485	ENOG4107EFR	Flavocytochrome c
FG381_RS03495	ENOG4108Z9W	Outer membrane porin
FG381_RS03515	ENOG4105D01	(LipO)protein
FG381_RS03520	ENOG4105DU0	nucleoside hydrolase
FG381_RS03545	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
FG381_RS03550	ENOG4105J76	Periplasmic binding protein
FG381_RS03555	ENOG4105E0A	ABC, transporter
FG381_RS03560	ENOG4105E0K	tonB-dependent siderophore receptor
FG381_RS03570	ENOG4105C09	Bile acid
FG381_RS03575	ENOG4107QHI	-hydrogenase
FG381_RS03595	ENOG4105CF7	AraC family transcriptional regulator
FG381_RS03600	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
FG381_RS03605	ENOG4105C8M	UPF0272 protein
FG381_RS03615	ENOG4105C5B	carbamate kinase
FG381_RS03625	ENOG4105S0E	allantoin catabolism protein
FG381_RS03640	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
FG381_RS03650	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FG381_RS03665	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
FG381_RS03670	ENOG4105V2T	cytochrome C
FG381_RS03685	ENOG4107QRG	dna polymerase iii
FG381_RS03690	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FG381_RS03710	ENOG4105DZW	Dipeptidase
FG381_RS03715	ENOG4106PMH	Extracellular solute-binding protein family 3
FG381_RS03765	ENOG4105KVH	Transcriptional regulator
FG381_RS03785	ENOG4105DFD	Na H antiporter
FG381_RS03795	ENOG4105CPC	Aldo Keto reductase
FG381_RS03805	ENOG4105KWW	Biogenesis protein
FG381_RS03810	ENOG4107QX9	Thiol disulfide interChange protein
FG381_RS03815	ENOG4105DA4	cytochrome c-type biogenesis protein
FG381_RS03820	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
FG381_RS03830	ENOG41060IM	Heme exporter protein
FG381_RS03835	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
FG381_RS03840	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
FG381_RS03850	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FG381_RS03855	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
FG381_RS03870	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FG381_RS03900	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FG381_RS03905	ENOG4105WH1	Two component transcriptional regulator luxr family
FG381_RS03910	ENOG41062D9	Histidine kinase
FG381_RS03915	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
FG381_RS03920	ENOG4108Z6B	deaminase
FG381_RS03940	ENOG4107QW4	alcohol dehydrogenase
FG381_RS03950	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FG381_RS03955	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FG381_RS03965	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FG381_RS03970	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FG381_RS04035	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FG381_RS04045	ENOG4107EFR	Flavocytochrome c
FG381_RS04055	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
FG381_RS04060	ENOG4105C08	Histidine kinase
FG381_RS04065	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
FG381_RS04075	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
FG381_RS04095	ENOG4105F2I	Transposase
FG381_RS04120	ENOG4107EFR	Flavocytochrome c
FG381_RS04135	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FG381_RS04140	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
FG381_RS04145	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FG381_RS04160	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
FG381_RS04165	ENOG4105C5H	ABC transporter
FG381_RS04180	ENOG4105CJR	Integral membrane protein (MviN
FG381_RS04185	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
FG381_RS04190	ENOG4108UT2	hemolysin iii
FG381_RS04195	ENOG4105D4A	Cell wall formation (By similarity)
FG381_RS04200	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FG381_RS04230	ENOG4105C2M	dna polymerase I
FG381_RS04255	ENOG4108Z4U	Ferredoxin
FG381_RS04260	ENOG4105DP0	ferredoxin-NADP reductase
FG381_RS04265	ENOG4108R3D	Electron transport complex
FG381_RS04270	ENOG4105CSM	endonuclease III
FG381_RS04280	ENOG4105BZU	Histidine kinase
FG381_RS04285	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FG381_RS04290	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FG381_RS04305	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FG381_RS04315	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
FG381_RS04340	ENOG4105K70	DNA-binding protein
FG381_RS04345	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FG381_RS04360	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FG381_RS04385	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FG381_RS04390	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FG381_RS04395	ENOG4107S74	Lysophospholipid transporter LplT
FG381_RS04405	ENOG4105EYH	Exonuclease
FG381_RS04410	ENOG4107RH8	nuclease SbcCD subunit D
FG381_RS04415	ENOG4107EFR	Flavocytochrome c
FG381_RS04420	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FG381_RS04425	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FG381_RS04450	ENOG4107R6U	sodium dicarboxylate symporter
FG381_RS04460	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
FG381_RS04465	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
FG381_RS04470	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FG381_RS04480	ENOG4105CVR	type I restriction-modification system
FG381_RS04485	ENOG4105DZR	Type I site-specific deoxyribonuclease
FG381_RS04495	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FG381_RS04500	ENOG4105EI2	Pseudouridine synthase
FG381_RS04505	ENOG4107QQB	Ribonuclease E
FG381_RS04525	ENOG4107EFR	Flavocytochrome c
FG381_RS04530	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FG381_RS04535	ENOG4105BZU	Histidine kinase
FG381_RS04555	ENOG4106UW1	Major Facilitator superfamily
FG381_RS04580	ENOG4105C26	Dehydrogenase
FG381_RS04585	ENOG4107S4Y	M20 DapE family protein YgeY
FG381_RS04605	ENOG4105C2C	drug resistance transporter, Bcr CflA
FG381_RS04615	ENOG4105KME	endoribonuclease L-psp
FG381_RS04640	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
FG381_RS04650	ENOG4108TU9	TRANSCRIPTIONal
FG381_RS04665	ENOG4107QI1	Mate efflux family protein
FG381_RS04670	ENOG4105D5Q	Arginine ornithine antiporter
FG381_RS04675	ENOG4105CRK	lysyL-tRNA synthetase
FG381_RS04680	ENOG4105CXN	decarboxylase
FG381_RS04685	ENOG4105D5Q	Arginine ornithine antiporter
FG381_RS04690	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FG381_RS04695	ENOG4105D5Q	Arginine ornithine antiporter
FG381_RS04725	ENOG4105CH2	amidohydrolase
FG381_RS04730	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FG381_RS04735	ENOG410829K	Lysine exporter protein (Lyse ygga)
FG381_RS04750	ENOG4105GJM	(LipO)protein
FG381_RS04760	ENOG4108Z4T	Peptidase M50
FG381_RS04775	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FG381_RS04795	ENOG4105UIB	(ABC) transporter
FG381_RS04800	ENOG4105C2J	ABC transporter
FG381_RS04820	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FG381_RS04825	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
FG381_RS04840	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
FG381_RS04845	ENOG4105D4P	Coproporphyrinogen iii oxidase
FG381_RS04850	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FG381_RS04870	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
FG381_RS04875	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
FG381_RS04905	ENOG4107RZZ	dna polymerase iii epsilon subunit
FG381_RS04910	ENOG4107R0W	ABC transporter
FG381_RS04915	ENOG4105E5Q	amino acid AbC transporter
FG381_RS04920	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FG381_RS04925	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FG381_RS04930	ENOG4105CP7	Triose-phosphate isomerase
FG381_RS04965	ENOG4105C4R	Atp-dependent dna helicase
FG381_RS04970	ENOG4105C8T	Leucyl-tRNA synthetase
FG381_RS04980	ENOG4105DJF	DNA polymerase III, delta' subunit
FG381_RS04985	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FG381_RS04995	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FG381_RS05000	ENOG4105DCT	glycerol dehydrogenase
FG381_RS05005	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FG381_RS05010	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FG381_RS05015	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FG381_RS05020	ENOG4105K5M	30s ribosomal protein S16
FG381_RS05025	ENOG4105E0C	molybdate abc transporter
FG381_RS05035	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
FG381_RS05040	ENOG4105C10	Electron transfer flavoprotein
FG381_RS05045	ENOG4105BZJ	Electron transfer flavoprotein
FG381_RS05050	ENOG4105W39	Membrane
FG381_RS05055	ENOG4105II7	pyrroline-5-carboxylate reductase
FG381_RS05060	ENOG4105DFA	alanine racemase domain protein
FG381_RS05075	ENOG4105WPN	DNA integration recombination invertion protein
FG381_RS05090	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FG381_RS05105	ENOG4105VDB	UPF0125 protein
FG381_RS05110	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FG381_RS05120	ENOG4105EHG	Permease protein
FG381_RS05125	ENOG4105E0A	ABC, transporter
FG381_RS05130	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FG381_RS05145	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FG381_RS05165	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
FG381_RS05185	ENOG4108Z86	Glutamine amidotransferase
FG381_RS05195	ENOG4105C6X	Major Facilitator
FG381_RS05235	ENOG4108IQE	Amp-dependent synthetase and ligase
FG381_RS05240	ENOG4108IQE	Amp-dependent synthetase and ligase
FG381_RS05245	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FG381_RS05250	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FG381_RS05255	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FG381_RS05260	ENOG4107RB3	L-asparaginase
FG381_RS05265	ENOG4108Z9W	Outer membrane porin
FG381_RS05290	ENOG4107RH7	Nicotinate phosphoribosyltransferase
FG381_RS05300	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
FG381_RS05305	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FG381_RS05310	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
FG381_RS05315	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FG381_RS05320	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FG381_RS05325	ENOG4105C3F	Signal peptidase i
FG381_RS05330	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FG381_RS05335	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FG381_RS05340	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FG381_RS05345	ENOG4105CHR	reductase
FG381_RS05350	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FG381_RS05355	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FG381_RS05360	ENOG4105VGS	50s ribosomal protein l32
FG381_RS05395	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
FG381_RS05400	ENOG4108IJ0	Aspartate ammonia-lyase
FG381_RS05405	ENOG4105E33	succinate dehydrogenase
FG381_RS05410	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FG381_RS05415	ENOG4105KME	endoribonuclease L-psp
FG381_RS05420	ENOG4105CB5	ATP-dependent DNA helicase recG
FG381_RS05425	ENOG4105C5Q	Transcriptional regulator
FG381_RS05430	ENOG4105IPI	Membrane
FG381_RS05435	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
FG381_RS05445	ENOG4105EJQ	L-serine dehydratase
FG381_RS05455	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
FG381_RS05465	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
FG381_RS05470	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FG381_RS05475	ENOG4105CK7	Sodium proline symporter
FG381_RS05480	ENOG4105DEF	Extracellular solute-binding protein, family 5
FG381_RS05500	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FG381_RS05505	ENOG4108ZAF	Molybdopterin
FG381_RS05510	ENOG4105M00	molybdopterin converting factor, subunit 1
FG381_RS05515	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FG381_RS05520	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
FG381_RS05580	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
FG381_RS05615	ENOG4105CH2	amidohydrolase
FG381_RS05630	ENOG4108IAB	Phoh family
FG381_RS05635	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
FG381_RS05640	ENOG4107QYX	exodeoxyribonuclease v alpha
FG381_RS05645	ENOG4107QKA	exodeoxyribonuclease V beta
FG381_RS05650	ENOG4105DSY	exodeoxyribonuclease V, gamma
FG381_RS05655	ENOG4108Z9W	Outer membrane porin
FG381_RS05665	ENOG4105CDU	Replicative dna helicase
FG381_RS05670	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FG381_RS05675	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FG381_RS05695	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FG381_RS05700	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FG381_RS05720	ENOG4108TFM	Kinase, PfkB family
FG381_RS05725	ENOG4108KD5	ADP-ribosylation crystallin J1
FG381_RS05760	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
FG381_RS05765	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FG381_RS05775	ENOG4105EPW	hflc protein
FG381_RS05780	ENOG4107QJR	hflk protein
FG381_RS05795	ENOG4105EU0	Major facilitator Superfamily
FG381_RS05805	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FG381_RS05810	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
FG381_RS05815	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FG381_RS05820	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FG381_RS05825	ENOG4105N21	Membrane
FG381_RS05845	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FG381_RS05850	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FG381_RS05855	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
FG381_RS05865	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FG381_RS05875	ENOG4108K5P	(LipO)protein
FG381_RS05880	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FG381_RS05885	ENOG4105BZU	Histidine kinase
FG381_RS05890	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FG381_RS05895	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FG381_RS05905	ENOG4105E2Z	phosphate ABC transporter (Permease
FG381_RS05910	ENOG4105C8U	phosphate abc transporter
FG381_RS05925	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FG381_RS05935	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FG381_RS05940	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FG381_RS05945	ENOG4105VJV	50s ribosomal protein L35
FG381_RS05950	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FG381_RS05955	ENOG4105C22	threonyL-tRNA synthetase
FG381_RS05970	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FG381_RS06050	ENOG4105CAG	UPF0210 protein
FG381_RS06065	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FG381_RS06080	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FG381_RS06085	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
FG381_RS06090	ENOG4105CRK	lysyL-tRNA synthetase
FG381_RS06120	ENOG4105CPC	Aldo Keto reductase
FG381_RS06125	ENOG4105NF4	modulator of drug activity
FG381_RS06130	ENOG4105WVQ	Fe-S assembly protein IscX
FG381_RS06135	ENOG4108ZIT	Ferredoxin, 2FE-2S
FG381_RS06140	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
FG381_RS06145	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
FG381_RS06150	ENOG4108Z4V	iron-sulfur cluster assembly
FG381_RS06155	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
FG381_RS06160	ENOG4105C3J	Cysteine desulfurase
FG381_RS06165	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
FG381_RS06175	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FG381_RS06190	ENOG4105DG4	malate L-lactate dehydrogenase
FG381_RS06215	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FG381_RS06220	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FG381_RS06225	ENOG4108VVQ	metallophosphoesterase
FG381_RS06235	ENOG4107TMZ	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
FG381_RS06240	ENOG4105CNU	cell division protein FtsK
FG381_RS06245	ENOG4105C3M	thioredoxin reductase
FG381_RS06255	ENOG4105EN6	Membrane
FG381_RS06260	ENOG4108YZA	Nitrogen regulatory protein pii
FG381_RS06270	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FG381_RS06275	ENOG4105EEI	dihydropteroate synthase
FG381_RS06280	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FG381_RS06285	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
FG381_RS06290	ENOG4105HBR	Rna-binding protein
FG381_RS06295	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FG381_RS06300	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
FG381_RS06305	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FG381_RS06310	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FG381_RS06315	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FG381_RS06325	ENOG4107QMP	dna polymerase iii subunits gamma and tau
FG381_RS06340	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FG381_RS06350	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FG381_RS06355	ENOG4105NRA	50s ribosomal protein l31 type b
FG381_RS06365	ENOG4107QI1	Mate efflux family protein
FG381_RS06370	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FG381_RS06375	ENOG4105D0M	Protease HtpX homolog
FG381_RS06380	ENOG4105CFV	Tetratricopeptide repeat protein
FG381_RS06390	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FG381_RS06395	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FG381_RS06400	ENOG4105CAT	Cytidine monophosphate kinase
FG381_RS06405	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FG381_RS06410	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FG381_RS06415	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FG381_RS06420	ENOG4105UYK	outer membrane protein a
FG381_RS06425	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FG381_RS06440	ENOG4105QAX	Iron-sulfur
FG381_RS06500	ENOG4105K8N	protein family UPF0079, ATPase
FG381_RS06505	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FG381_RS06515	ENOG41080IJ	Diacylglycerol kinase
FG381_RS06520	ENOG4105C8V	SAICAR synthetase
FG381_RS06525	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FG381_RS06530	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
FG381_RS06535	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FG381_RS06550	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FG381_RS06560	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
FG381_RS06585	ENOG4108MR7	Arylsulfotransferase
FG381_RS06590	ENOG4107QTF	adenylosuccinate lyase
FG381_RS06595	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
FG381_RS06600	ENOG4105E0C	molybdate abc transporter
FG381_RS06605	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
FG381_RS06610	ENOG4105F4R	Transcriptional regulator mode
FG381_RS06620	ENOG4105CD8	aminopeptidase N
FG381_RS06625	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FG381_RS06640	ENOG4108S24	Fumarate reduCtase
FG381_RS06675	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FG381_RS06680	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
FG381_RS06685	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FG381_RS06700	ENOG4105CDY	transcriptional regulatory protein
FG381_RS06705	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
FG381_RS06710	ENOG4105WH1	Two component transcriptional regulator luxr family
FG381_RS06715	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
FG381_RS06720	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FG381_RS06735	ENOG4105CFG	Acts as a chaperone (By similarity)
FG381_RS06745	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FG381_RS06760	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
FG381_RS06770	ENOG4105K63	Thioredoxin
FG381_RS06785	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FG381_RS06795	ENOG4105CEY	Amp-dependent synthetase and ligase
FG381_RS06805	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FG381_RS06810	ENOG4105VAW	lrga family
FG381_RS06815	ENOG41067MG	lrgb family
FG381_RS06820	ENOG4105EA8	2-Nitropropane dioxygenase
FG381_RS06830	ENOG4108ZCF	integral membrane protein
FG381_RS06835	ENOG4108004	Modulates RecA activity (By similarity)
FG381_RS06840	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FG381_RS06860	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FG381_RS06865	ENOG4108UMI	ABC transporter, permease
FG381_RS06875	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FG381_RS06880	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FG381_RS06885	ENOG4106RHG	Yeca family
FG381_RS06890	ENOG4105C5H	ABC transporter
FG381_RS06920	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FG381_RS06925	ENOG4105ERG	peptidase m48, ste24p
FG381_RS06930	ENOG4105CAY	ferredoxin--nadp reductase
FG381_RS06935	ENOG4105D1F	ATP-binding protein
FG381_RS06945	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FG381_RS06950	ENOG4105CHH	sulfate transporter
FG381_RS06970	ENOG4105M15	transport protein ExbD
FG381_RS06975	ENOG4105M8K	biopolymer transport protein
FG381_RS06980	ENOG4105D05	Receptor
FG381_RS06985	ENOG4105DHS	permease protein
FG381_RS06990	ENOG4105CM4	permease protein
FG381_RS06995	ENOG4108IPW	abc transporter atp-binding protein
FG381_RS07010	ENOG4107R1I	NAD-dependent malic enzyme
FG381_RS07020	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FG381_RS07025	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
FG381_RS07035	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
FG381_RS07040	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FG381_RS07045	ENOG4108S0S	Nucleotidyl transferase
FG381_RS07050	ENOG4105EHM	Aminoglycoside phosphotransferase
FG381_RS07060	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FG381_RS07065	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
FG381_RS07070	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FG381_RS07085	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FG381_RS07090	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
FG381_RS07095	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FG381_RS07100	ENOG4108JU5	Magnesium and cobalt efflux protein
FG381_RS07105	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FG381_RS07110	ENOG4105C9A	Phoh family
FG381_RS07125	ENOG4105DWF	phosphomethylpyrimidine kinase
FG381_RS07130	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FG381_RS07135	ENOG4105D16	lipopolysaccharide heptosyltransferase i
FG381_RS07145	ENOG4107QKV	phosphomannomutase
FG381_RS07150	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
FG381_RS07155	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
FG381_RS07160	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
FG381_RS07165	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
FG381_RS07170	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FG381_RS07175	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
FG381_RS07190	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
FG381_RS07205	ENOG4105D78	K07001 NTE family protein
FG381_RS07215	ENOG4108RS6	transposase
FG381_RS07220	ENOG4105CMR	udp-glucose 4-epimerase
FG381_RS07230	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FG381_RS07235	ENOG4107RDB	Major Facilitator
FG381_RS07250	ENOG4105C59	p-type ATPase
FG381_RS07255	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FG381_RS07260	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FG381_RS07275	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FG381_RS07280	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FG381_RS07295	ENOG4105C9M	aspartyl-trna synthetase
FG381_RS07325	ENOG4107W7X	Aldolase
FG381_RS07330	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
FG381_RS07335	ENOG4105CD5	CoA-binding domain protein
FG381_RS07340	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FG381_RS07345	ENOG4107RP9	extracellular solute-binding protein, family 3
FG381_RS07350	ENOG4105EAD	ABC transporter
FG381_RS07355	ENOG4105DRP	amino acid AbC transporter
FG381_RS07360	ENOG4105CDA	abc transporter atp-binding protein
FG381_RS07365	ENOG4105C2X	Arabinose 5-phosphate isomerase
FG381_RS07385	ENOG4108IUZ	ABC transporter
FG381_RS07390	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FG381_RS07395	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
FG381_RS07400	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FG381_RS07405	ENOG4105CEN	a g-specific adenine glycosylase
FG381_RS07410	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
FG381_RS07420	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FG381_RS07430	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FG381_RS07435	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
FG381_RS07440	ENOG4105C1J	atp-dependent rna helicase
FG381_RS07450	ENOG4105EWC	Purine nucleoside phosphorylase
FG381_RS07455	ENOG4105C3G	gtp-binding protein
FG381_RS07465	ENOG4105D3R	alkyl hydroperoxide reductase
FG381_RS07470	ENOG4108JU3	Alkyl hydroperoxide reductase
FG381_RS07480	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FG381_RS07485	ENOG4106H78	methyltransferase
FG381_RS07495	ENOG4105C9X	ppx gppa phosphatase
FG381_RS07500	ENOG4105CAK	Cell division ATP-binding protein ftsE
FG381_RS07505	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
FG381_RS07510	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FG381_RS07515	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
FG381_RS07520	ENOG4105WH1	Two component transcriptional regulator luxr family
FG381_RS07525	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
FG381_RS07530	ENOG4107YZP	Rhodanese domain protein
FG381_RS07540	ENOG4105CN1	protease
FG381_RS07545	ENOG4105D06	uba thif-type nad fad binding protein
FG381_RS07550	ENOG4105D07	Signal peptide peptidase, SppA
FG381_RS07565	ENOG4105CKI	cobalamin synthesis protein
FG381_RS07570	ENOG4105DR4	Methyltransferase
FG381_RS07575	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FG381_RS07580	ENOG4105D1S	lipid A biosynthesis
FG381_RS07590	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FG381_RS07595	ENOG4105C31	Tryptophanyl-tRNA synthetase
FG381_RS07600	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
FG381_RS07610	ENOG4107SC1	transglycosylase
FG381_RS07615	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FG381_RS07635	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FG381_RS07640	ENOG4105CSR	polyphosphate kinase 2
FG381_RS07645	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FG381_RS07655	ENOG4105C5H	ABC transporter
FG381_RS07665	ENOG4105C6T	cysteine synthase
FG381_RS07670	ENOG4108IQE	Amp-dependent synthetase and ligase
FG381_RS07675	ENOG4105CSA	Coproporphyrinogen iii oxidase
FG381_RS07680	ENOG4107QHI	-hydrogenase
FG381_RS07695	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FG381_RS07700	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FG381_RS07705	ENOG4105C2W	permease
FG381_RS07710	ENOG4105BZM	domain protein
FG381_RS07720	ENOG4105DRP	amino acid AbC transporter
FG381_RS07725	ENOG4105EZ7	amino acid ABC transporter
FG381_RS07730	ENOG4107QXX	ABC transporter
FG381_RS07735	ENOG4105C37	(CBS) domain
FG381_RS07740	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FG381_RS07755	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
FG381_RS07760	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FG381_RS07765	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FG381_RS07775	ENOG4105ES5	Histidine kinase
FG381_RS07785	ENOG4105C1A	potassium transporter peripheral membrane
FG381_RS07790	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
FG381_RS07810	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FG381_RS07820	ENOG4105EYM	Major Facilitator superfamily
FG381_RS07825	ENOG4105I08	Pseudouridine synthase
FG381_RS07830	ENOG4105CGK	Exodeoxyribonuclease III
FG381_RS07835	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FG381_RS07840	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FG381_RS07845	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FG381_RS07850	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FG381_RS07870	ENOG4105CJN	penicillin-binding protein
FG381_RS07875	ENOG4105CNI	cell division protein FtsW
FG381_RS07880	ENOG4105K6T	rare lipoprotein A
FG381_RS07885	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FG381_RS07905	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
FG381_RS07910	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
FG381_RS07920	ENOG4108Z43	UPF0250 protein
FG381_RS07930	ENOG41082WC	Transport-associated protein
FG381_RS07945	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FG381_RS07950	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FG381_RS07955	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FG381_RS07960	ENOG4105VG0	50S ribosomal protein l34
FG381_RS07970	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
FG381_RS07985	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FG381_RS07995	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FG381_RS08005	ENOG4107QJE	Chromosome Partitioning Protein
FG381_RS08010	ENOG4105FA0	parb-like partition protein
FG381_RS08020	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
FG381_RS08025	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FG381_RS08035	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FG381_RS08050	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FG381_RS08055	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FG381_RS08065	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FG381_RS08070	ENOG4105C25	Primosomal protein n'
FG381_RS08085	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FG381_RS08100	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FG381_RS08115	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FG381_RS08120	ENOG4105BZS	acriflavin resistance protein
FG381_RS08135	ENOG4105C0H	protease
FG381_RS08140	ENOG4105DHQ	Histidine kinase
FG381_RS08145	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
FG381_RS08160	ENOG4108VWS	Yaeq family
FG381_RS08165	ENOG4108Z18	K06886 hemoglobin
FG381_RS08175	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FG381_RS08180	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FG381_RS08210	ENOG4105EJ5	oxidoreductase gamma subunit
FG381_RS08215	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
FG381_RS08220	ENOG4105DDK	oxidoreductase, beta subunit
FG381_RS08225	ENOG4105BZ8	glutamate synthase
FG381_RS08230	ENOG4105BZU	Histidine kinase
FG381_RS08235	ENOG4105WH1	Two component transcriptional regulator luxr family
FG381_RS08245	ENOG4105GXZ	Ferredoxin-type protein NapH
FG381_RS08250	ENOG4108BGM	Quinol dehydrogenase periplasmic component
FG381_RS08255	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FG381_RS08270	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
FG381_RS08275	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FG381_RS08285	ENOG4108Z33	Thiol disulfide Interchange Protein
FG381_RS08295	ENOG4105C75	arginyL-tRNA synthetase
FG381_RS08300	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
FG381_RS08310	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FG381_RS08330	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FG381_RS08340	ENOG4105PM1	preprotein translocase subunit SecE
FG381_RS08355	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FG381_RS08360	ENOG4108VZM	50s ribosomal protein L10
FG381_RS08365	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FG381_RS08370	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FG381_RS08375	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FG381_RS08380	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FG381_RS08385	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FG381_RS08395	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FG381_RS08400	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FG381_RS08405	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FG381_RS08410	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FG381_RS08415	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FG381_RS08420	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FG381_RS08425	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FG381_RS08430	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FG381_RS08435	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FG381_RS08440	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FG381_RS08445	ENOG41084PQ	50s ribosomal protein l29
FG381_RS08450	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FG381_RS08455	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FG381_RS08460	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FG381_RS08465	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FG381_RS08470	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FG381_RS08480	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FG381_RS08485	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FG381_RS08490	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FG381_RS08495	ENOG4105VPB	50S ribosomal protein L30
FG381_RS08500	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FG381_RS08505	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FG381_RS08510	ENOG41067V7	50S ribosomal protein L36
FG381_RS08515	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FG381_RS08520	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FG381_RS08535	ENOG4108ZT0	50S ribosomal protein l17
FG381_RS08540	ENOG4105VEJ	Heat shock protein
FG381_RS08545	ENOG4105D52	delta-aminolevulinic acid dehydratase
FG381_RS08555	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FG381_RS08570	ENOG4105XQ6	frataxin-like protein
FG381_RS08575	ENOG4108JQC	penicillin-binding protein 1A
FG381_RS08585	ENOG4105DHJ	ABC, transporter
FG381_RS08590	ENOG4105CY3	ABC transporter, permease
FG381_RS08595	ENOG4107PE3	Mammalian cell entry related domain protein
FG381_RS08600	ENOG410903C	(LipO)protein
FG381_RS08615	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FG381_RS08620	ENOG4105K59	histidine triad (HIT) protein
FG381_RS08625	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FG381_RS08635	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FG381_RS08640	ENOG4105C0H	protease
FG381_RS08645	ENOG4107QNR	UPF0135 protein
FG381_RS08650	ENOG4107MKT	Stringent starvation protein a
FG381_RS08685	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FG381_RS08690	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
FG381_RS08730	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FG381_RS08740	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
FG381_RS08810	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FG381_RS08850	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FG381_RS08855	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
FG381_RS08860	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
FG381_RS08865	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FG381_RS08870	ENOG4108UJD	30S ribosomal protein S9
FG381_RS08880	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
FG381_RS08895	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FG381_RS08905	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FG381_RS08910	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
FG381_RS08915	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FG381_RS08920	ENOG4108R6K	riboflavin synthase, subunit alpha
FG381_RS08925	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FG381_RS08935	ENOG4107YIM	Involved in the transcription termination process (By similarity)
FG381_RS08940	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FG381_RS08945	ENOG4108ZAI	phosphatidylglycerophosphatase a
FG381_RS08950	ENOG4105CEV	competence damage-inducible protein
FG381_RS08980	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
FG381_RS08990	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FG381_RS08995	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FG381_RS09005	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FG381_RS09010	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FG381_RS09015	ENOG41079UR	PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity)
FG381_RS09025	ENOG4108V6E	Cell division protein mraZ
FG381_RS09045	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FG381_RS09055	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FG381_RS09060	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FG381_RS09070	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FG381_RS09075	ENOG4105DFU	Cell wall formation (By similarity)
FG381_RS09080	ENOG4105CPF	Cell wall formation (By similarity)
FG381_RS09085	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
FG381_RS09095	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FG381_RS09100	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FG381_RS09110	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FG381_RS09125	ENOG4108RS6	transposase
FG381_RS09145	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
FG381_RS09155	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FG381_RS09165	ENOG4105EAH	synthase
FG381_RS09170	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FG381_RS09175	ENOG4105K46	50S ribosomal protein l27
FG381_RS09180	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FG381_RS09185	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FG381_RS09190	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FG381_RS09205	ENOG4108ZZF	transport protein (ExbD)
FG381_RS09210	ENOG4105E02	MotA TolQ exbB proton channel
FG381_RS09215	ENOG4107YD3	Thioesterase
FG381_RS09230	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FG381_RS09240	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FG381_RS09245	ENOG4105D0M	Protease HtpX homolog
FG381_RS09250	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FG381_RS09255	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FG381_RS09260	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FG381_RS09280	ENOG4108VIA	integral membrane protein
FG381_RS09295	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FG381_RS09305	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FG381_RS09310	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
FG381_RS09320	ENOG4105DFU	Cell wall formation (By similarity)
FG381_RS09330	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
FG381_RS09335	ENOG4105CJW	magnesium transporter
FG381_RS09350	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
FG381_RS09355	ENOG4105CV1	Transketolase (EC 2.2.1.1)
FG381_RS09360	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FG381_RS09365	ENOG4105EXC	Acyl-transferase
FG381_RS09370	ENOG4105BZA	Phosphoglycerate kinase
FG381_RS09375	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FG381_RS09380	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FG381_RS09385	ENOG4105DQR	SNARE associated Golgi
FG381_RS09390	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FG381_RS09395	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FG381_RS09400	ENOG4108I6E	Sulfatase
FG381_RS09405	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FG381_RS09420	ENOG4105DJ0	Poly(A) Polymerase
FG381_RS09435	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
FG381_RS09445	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
FG381_RS09450	ENOG4105N42	UPF0307 protein
FG381_RS09455	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FG381_RS09460	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FG381_RS09465	ENOG4105VIE	preprotein translocase, subunit YajC
FG381_RS09470	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FG381_RS09475	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FG381_RS09500	ENOG4105DIJ	Phosphoethanolamine transferase
FG381_RS09505	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FG381_RS09510	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
FG381_RS09515	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FG381_RS09520	ENOG4105HF0	Membrane
FG381_RS09540	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FG381_RS09545	ENOG41090R7	Ferric uptake
FG381_RS09555	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FG381_RS09570	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
FG381_RS09585	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FG381_RS09600	ENOG4105BZ1	(ABC) transporter
FG381_RS09605	ENOG4105DXC	membrane
FG381_RS09615	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FG381_RS09620	ENOG4105C03	ribonuclease
FG381_RS09625	ENOG4105CJB	Exodeoxyribonuclease I
FG381_RS09635	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FG381_RS09640	ENOG4105CX6	glutaminyL-tRNA synthetase
FG381_RS09650	ENOG4105CJ2	(LipO)protein
FG381_RS09655	ENOG4105C0B	DNA polymerase III (alpha subunit)
FG381_RS09690	ENOG4105BZG	amino acid carrier protein
FG381_RS09695	ENOG4105CH7	arginosuccinase
FG381_RS09725	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FG381_RS09745	ENOG4107EFR	Flavocytochrome c
FG381_RS09755	ENOG4108RRZ	Transcription elongation factor GreB
FG381_RS09760	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FG381_RS09765	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FG381_RS09770	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FG381_RS09775	ENOG4105DSJ	YicC domain protein
FG381_RS09780	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
FG381_RS09785	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FG381_RS09790	ENOG4105CSA	Coproporphyrinogen iii oxidase
FG381_RS09800	ENOG4105CUX	Signal transduction histidine kinase
FG381_RS09805	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FG381_RS09815	ENOG4105EVD	ribosomal RNA large subunit methyltransferase N
FG381_RS09845	ENOG4105CGK	Exodeoxyribonuclease III
FG381_RS09855	ENOG4105DBV	ornithine carbamoyltransferase
FG381_RS09860	ENOG4105DGW	oligopeptidase A
FG381_RS09865	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FG381_RS09870	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FG381_RS09875	ENOG4105BZU	Histidine kinase
FG381_RS09880	ENOG4105E66	phosphoriboisomerase A
FG381_RS09885	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
FG381_RS09890	ENOG4105CQ7	ATP-dependent helicase
FG381_RS09895	ENOG41061WM	D-Alanyl-D-Alanine
FG381_RS09900	ENOG4105DF6	Fe-S oxidoreductase
FG381_RS09910	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
FG381_RS09915	ENOG4107XID	2'-5' rna ligase
FG381_RS09945	ENOG4105D1H	recombination factor protein RarA
FG381_RS09960	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
FG381_RS09965	ENOG4105FE9	pseudouridine synthase
FG381_RS09975	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
FG381_RS09980	ENOG4105CHV	Transcription elongation factor NusA
FG381_RS09985	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FG381_RS09990	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FG381_RS09995	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FG381_RS10000	ENOG4105CI3	gtp-binding protein typa
FG381_RS10005	ENOG4105K5B	UPF0225 protein
FG381_RS10010	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FG381_RS10015	ENOG4107RTG	Major Facilitator superfamily
FG381_RS10020	ENOG4105ENX	hydrolase
FG381_RS10025	ENOG4107RSM	transcriptional regulator
FG381_RS10030	ENOG4106TNF	Periplasmic binding protein
FG381_RS10055	ENOG4105CQB	FAD linked oxidase domain protein
FG381_RS10060	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FG381_RS10075	ENOG4107R3N	Filamentation induced by cAMP protein fic
FG381_RS10080	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
FG381_RS10090	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
FG381_RS10100	ENOG4107EFR	Flavocytochrome c
FG381_RS10105	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FG381_RS10110	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FG381_RS10115	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FG381_RS10135	ENOG4107TT2	Auxin Efflux Carrier
FG381_RS10155	ENOG4108J2R	molybdopterin oxidoreductase
FG381_RS10160	ENOG4105E4P	ATPase (AAA
FG381_RS10170	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
FG381_RS10175	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FG381_RS10185	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FG381_RS10190	ENOG4105DTN	riboflavin biosynthesis protein ribF
FG381_RS10195	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FG381_RS10215	ENOG4105EAM	Na Pi-cotransporter
FG381_RS10220	ENOG4105DUM	transcriptional regulator, lysR family
FG381_RS10235	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
FG381_RS10240	ENOG4105KDC	50s ribosomal protein l28
FG381_RS10245	ENOG4105W0E	50S ribosomal protein L33
FG381_RS10250	ENOG4105CSH	Transporter
FG381_RS10255	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FG381_RS10265	ENOG4105KTH	gatB Yqey
FG381_RS10275	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FG381_RS10280	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FG381_RS10290	ENOG4105C1J	atp-dependent rna helicase
FG381_RS10300	ENOG4105C8P	)-transporter
FG381_RS10310	ENOG4105E0F	Histidine kinase
FG381_RS10325	ENOG41072GX	Peptidase M22 Glycoprotease
FG381_RS10335	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
FG381_RS10345	ENOG4108IA2	Sodium pantothenate symporter
FG381_RS10350	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FG381_RS10355	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FG381_RS10360	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FG381_RS10365	ENOG4108I0Q	anthranilate phosphoribosyltransferase
FG381_RS10400	ENOG4105HDK	L-asparaginase
FG381_RS10410	ENOG4105CDH	Citrulline--aspartate ligase
FG381_RS10415	ENOG4105PGM	cation diffusion facilitator family transporter
FG381_RS10425	ENOG4108RS6	transposase
FG381_RS10435	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FG381_RS10440	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FG381_RS10445	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FG381_RS10450	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
FG381_RS10455	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
FG381_RS10460	ENOG4105DB7	PHP domain protein
FG381_RS10465	ENOG4105BZG	amino acid carrier protein
FG381_RS10490	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
FG381_RS10500	ENOG4105DVT	helicase
FG381_RS10515	ENOG4105C8J	)-transporter
FG381_RS10520	ENOG4105C8J	)-transporter
FG381_RS10525	ENOG4105C8J	)-transporter
FG381_RS10530	ENOG4105C8J	)-transporter
FG381_RS10545	ENOG4105CQ0	ABC transporter
FG381_RS10550	ENOG4105CNM	Receptor
FG381_RS10565	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
FG381_RS10575	ENOG4105DXC	membrane
FG381_RS10585	ENOG4105CVE	Lytic murein transglycosylase
FG381_RS10590	ENOG4105DGU	Histone deacetylase
FG381_RS10600	ENOG4106P37	HTH-type transcriptional regulator YjhI
FG381_RS10605	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FG381_RS10610	ENOG4105C01	Dihydroxy-acid dehydratase
FG381_RS10615	ENOG4105C6Z	Gluconate
FG381_RS10635	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FG381_RS10640	ENOG4105C34	Pseudouridine synthase
FG381_RS10645	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
FG381_RS10650	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
FG381_RS10680	ENOG4108RS6	transposase
FG381_RS10690	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FG381_RS10695	ENOG4108MR7	Arylsulfotransferase
FG381_RS10715	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FG381_RS10720	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FG381_RS10730	ENOG4105E96	Colicin v production protein
FG381_RS10735	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FG381_RS10755	ENOG4108JQB	penicillin-binding protein 1C
FG381_RS10770	ENOG4108MR7	Arylsulfotransferase
FG381_RS10775	ENOG4105RK9	auxin efflux carrier
FG381_RS10815	ENOG4108UHJ	MAF-like protein
FG381_RS10820	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
FG381_RS10830	ENOG4105FCD	Major Facilitator
FG381_RS10835	ENOG4105CD3	dihydroorotase
FG381_RS10850	ENOG4105CH2	amidohydrolase
FG381_RS10855	ENOG4105FDP	GntR family transcriptional regulator
FG381_RS10870	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
FG381_RS10885	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FG381_RS10900	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
FG381_RS10905	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
FG381_RS10910	ENOG4105D7W	serine acetyltransferase
FG381_RS10920	ENOG4105GNX	MltA-interacting MipA family protein
FG381_RS10925	ENOG4107R3N	Filamentation induced by cAMP protein fic
FG381_RS10940	ENOG4109015	Biopolymer transport protein exbD tolR
FG381_RS10960	ENOG4108JJB	ABC transporter
FG381_RS10975	ENOG4105D05	Receptor
FG381_RS10980	ENOG4105D4P	Coproporphyrinogen iii oxidase
FG381_RS10985	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
FG381_RS10995	ENOG4105DA5	(ABC) transporter
FG381_RS11000	ENOG4105E3A	(ABC) transporter
FG381_RS11010	ENOG4107EFR	Flavocytochrome c
FG381_RS11020	ENOG4105D01	(LipO)protein
FG381_RS11025	ENOG4105DTQ	mandelate racemase muconate lactonizing
FG381_RS11040	ENOG4105F1A	Pyruvate formate-lyase
FG381_RS11045	ENOG4105CDA	abc transporter atp-binding protein
FG381_RS11050	ENOG4105E5Q	amino acid AbC transporter
FG381_RS11055	ENOG4106PMH	Extracellular solute-binding protein family 3
FG381_RS11070	ENOG4105CH7	arginosuccinase
FG381_RS11075	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
FG381_RS11080	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
FG381_RS11090	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FG381_RS11100	ENOG4105CE9	30S ribosomal protein S2
FG381_RS11105	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FG381_RS11115	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FG381_RS11120	ENOG4105C0D	helicase
FG381_RS11135	ENOG4105CEE	C4-dicarboxylate transporter
FG381_RS11150	ENOG4105KNE	Phosphatidate cytidylyltransferase
FG381_RS11155	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
FG381_RS11165	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FG381_RS11170	ENOG4105DZP	Membrane-associated zinc metalloprotease
FG381_RS11175	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FG381_RS11195	ENOG4105CH6	catalase
FG381_RS11215	ENOG4105CFP	Peptidase U32
FG381_RS11225	ENOG4105F8V	Hydrolase, tatD family
FG381_RS11250	ENOG4107EFR	Flavocytochrome c
FG381_RS11255	ENOG4107EFR	Flavocytochrome c
FG381_RS11305	ENOG4105BZ8	glutamate synthase
FG381_RS11315	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
FG381_RS11325	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FG381_RS11350	ENOG4108P8G	outer membrane autotransporter barrel
FG381_RS11390	ENOG41064T2	transcriptional regulator, lysR family
FG381_RS11405	ENOG4108I5C	dEAD DEAH box helicase
FG381_RS11410	ENOG4105CD3	dihydroorotase
FG381_RS11435	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
FG381_RS11455	ENOG4105CKU	formyltetrahydrofolate synthetase
FG381_RS11460	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FG381_RS11480	ENOG4105D01	(LipO)protein
FG381_RS11495	ENOG4105EFZ	amidohydrolase
FG381_RS11500	ENOG4107R7I	amino acid
FG381_RS11525	ENOG4105DYB	Isoaspartyl dipeptidase
FG381_RS11540	ENOG4107S2Z	UPF0761 membrane protein
FG381_RS11550	ENOG4107TF3	peptidylprolyl cis-trans isomerase
FG381_RS11555	ENOG4107835	probably involved in intracellular septation (By similarity)
FG381_RS11565	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
FG381_RS11570	ENOG4108HPG	-acetyltransferase
FG381_RS11580	ENOG4105EAC	phosphoserine phosphatase
FG381_RS11585	ENOG4107EFR	Flavocytochrome c
FG381_RS11590	ENOG4105C79	DNA protecting protein DprA
FG381_RS11605	ENOG4107EFR	Flavocytochrome c
FG381_RS11660	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FG381_RS11665	ENOG4105ECY	inositol monophosphatase
FG381_RS11670	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FG381_RS11680	ENOG4108C33	Resolvase
FG381_RS11725	ENOG4105C2C	drug resistance transporter, Bcr CflA
FG381_RS11730	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
FG381_RS11735	ENOG410829K	Lysine exporter protein (Lyse ygga)
FG381_RS11745	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FG381_RS11795	ENOG4105C2M	dna polymerase I
FG381_RS11840	ENOG41063XI	Toxic component of a toxin-antitoxin (TA) module. A
FG381_RS11845	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
FG381_RS11885	ENOG4105CAR	Terminase, large subunit
FG381_RS11925	ENOG4105TKZ	Tail Sheath
FG381_RS11975	ENOG4108T86	baseplate J family protein
FG381_RS11990	ENOG4105DFP	Integrase
FG381_RS12085	ENOG4105CFU	surface antigen
FG381_RS12115	ENOG4105D22	carbon starvation protein
FG381_RS12125	ENOG4105F27	Major Facilitator
FG381_RS12150	ENOG4105QUH	Domain of unknown function (DUF2088)
FG381_RS12165	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FG381_RS12175	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FG381_RS12190	ENOG4107S6Z	Na H antiporter
FG381_RS12210	ENOG4107QPK	)-transporter
FG381_RS12215	ENOG4105DWF	phosphomethylpyrimidine kinase
FG381_RS12220	ENOG4108J2R	molybdopterin oxidoreductase
FG381_RS12230	ENOG4108ETH	Formylglycinamide ribotide synthetase
FG381_RS12235	ENOG4105CXN	decarboxylase
FG381_RS12255	ENOG4105C8Y	Acetylornithine aminotransferase
FG381_RS12260	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FG381_RS12290	ENOG4105CDA	abc transporter atp-binding protein
FG381_RS12295	ENOG4105E5Q	amino acid AbC transporter
FG381_RS12345	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FG381_RS12350	ENOG4105BZU	Histidine kinase
FG381_RS12380	ENOG4105C45	hydrogenase expression formation protein (HypE)
FG381_RS12385	ENOG4105CQS	hydrogenase expression formation protein HypD
FG381_RS12400	ENOG4107RSS	Hydrogenase accessory protein HypB
FG381_RS12405	ENOG41081J6	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
FG381_RS12420	ENOG4105E3S	small subunit
FG381_RS12425	ENOG4105DPX	Hydrogenase, large subunit
FG381_RS12430	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
FG381_RS12440	ENOG4105D01	(LipO)protein
FG381_RS12520	ENOG4108P8G	outer membrane autotransporter barrel
FG381_RS12555	ENOG4105HHA	aminodeoxychorismate lyase
FG381_RS12570	ENOG4106UW1	Major Facilitator superfamily
FG381_RS12595	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)