locus-tag	class	description
SynBIOSU31_RS00005	COG0592	DNA-directed DNA polymerase activity
SynBIOSU31_RS00015	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynBIOSU31_RS00025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynBIOSU31_RS00035	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SynBIOSU31_RS00050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynBIOSU31_RS00055	COG0552	protein localization to endoplasmic reticulum
SynBIOSU31_RS00060	COG2208	phosphoserine phosphatase activity
SynBIOSU31_RS00065	COG0165	Argininosuccinate lyase
SynBIOSU31_RS00070	COG0724	RNA recognition motif
SynBIOSU31_RS00075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynBIOSU31_RS00085	COG2081	HI0933 family
SynBIOSU31_RS00090	COG1459	type II secretion system
SynBIOSU31_RS00100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SynBIOSU31_RS00105	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SynBIOSU31_RS00110	COG0484	heat shock protein binding
SynBIOSU31_RS00120	COG1162	GTPase activity
SynBIOSU31_RS00125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SynBIOSU31_RS00130	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SynBIOSU31_RS00135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SynBIOSU31_RS00140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynBIOSU31_RS00145	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SynBIOSU31_RS00150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynBIOSU31_RS00155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SynBIOSU31_RS00160	COG0511	ligase activity, forming carbon-carbon bonds
SynBIOSU31_RS00165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SynBIOSU31_RS00225	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SynBIOSU31_RS00230	COG0519	Catalyzes the synthesis of GMP from XMP
SynBIOSU31_RS00230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SynBIOSU31_RS00260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SynBIOSU31_RS00275	COG0768	penicillin binding
SynBIOSU31_RS00280	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_RS00285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynBIOSU31_RS00295	COG2022	thiamine diphosphate biosynthetic process
SynBIOSU31_RS00310	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SynBIOSU31_RS00315	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SynBIOSU31_RS00325	COG1215	transferase activity, transferring glycosyl groups
SynBIOSU31_RS00330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SynBIOSU31_RS00340	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SynBIOSU31_RS00345	COG0740	serine-type endopeptidase activity
SynBIOSU31_RS00350	COG0544	peptidyl-prolyl cis-trans isomerase activity
SynBIOSU31_RS00355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SynBIOSU31_RS00360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SynBIOSU31_RS00365	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SynBIOSU31_RS00375	COG0037	tRNA processing
SynBIOSU31_RS00385	COG0556	nucleotide-excision repair
SynBIOSU31_RS00390	COG0527	aspartate kinase activity
SynBIOSU31_RS00400	COG2082	Precorrin-8x methylmutase
SynBIOSU31_RS00410	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SynBIOSU31_RS00420	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SynBIOSU31_RS00435	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_RS00440	COG0653	protein targeting
SynBIOSU31_RS00445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynBIOSU31_RS00465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynBIOSU31_RS00515	COG1088	dTDP-glucose 4,6-dehydratase activity
SynBIOSU31_RS00530	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_RS00530	COG1216	Glycosyl transferase, family 2
SynBIOSU31_RS00535	COG1215	transferase activity, transferring glycosyl groups
SynBIOSU31_RS00555	COG2192	nodulation
SynBIOSU31_RS00560	COG1045	serine acetyltransferase
SynBIOSU31_RS00565	COG1725	Transcriptional regulator
SynBIOSU31_RS00570	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SynBIOSU31_RS00575	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SynBIOSU31_RS00580	COG1372	Participates in initiation and elongation during chromosome replication
SynBIOSU31_RS00580	COG0187	DNA topoisomerase II activity
SynBIOSU31_RS00590	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynBIOSU31_RS00595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SynBIOSU31_RS00600	COG0386	Belongs to the glutathione peroxidase family
SynBIOSU31_RS00615	COG2239	Acts as a magnesium transporter
SynBIOSU31_RS00620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_RS00625	COG2267	carboxylic ester hydrolase activity
SynBIOSU31_RS00655	COG0802	atpase or kinase
SynBIOSU31_RS00660	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SynBIOSU31_RS00665	COG0586	Pfam SNARE associated Golgi protein
SynBIOSU31_RS00670	COG0629	single-stranded DNA binding
SynBIOSU31_RS00680	COG1792	Involved in formation and maintenance of cell shape
SynBIOSU31_RS00695	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_RS00700	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SynBIOSU31_RS00715	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SynBIOSU31_RS00720	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynBIOSU31_RS00725	COG0515	serine threonine protein kinase
SynBIOSU31_RS00725	COG1357	PFAM Pentapeptide repeats (8 copies)
SynBIOSU31_RS00730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SynBIOSU31_RS00735	COG2255	four-way junction helicase activity
SynBIOSU31_RS00745	COG1473	amidohydrolase
SynBIOSU31_RS00760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SynBIOSU31_RS00765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynBIOSU31_RS00780	COG0493	'glutamate synthase
SynBIOSU31_RS00780	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynBIOSU31_RS00800	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynBIOSU31_RS00810	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SynBIOSU31_RS00815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SynBIOSU31_RS00820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SynBIOSU31_RS00825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_RS00830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SynBIOSU31_RS00835	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SynBIOSU31_RS00835	COG0662	Cupin 2, conserved barrel domain protein
SynBIOSU31_RS00840	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SynBIOSU31_RS00850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBIOSU31_RS00855	COG0571	ribonuclease III activity
SynBIOSU31_RS00900	COG0058	SHG alpha-glucan phosphorylase activity
SynBIOSU31_RS00905	COG0475	glutathione-regulated potassium exporter activity
SynBIOSU31_RS00930	COG1304	FMN binding
SynBIOSU31_RS00935	COG0277	FAD linked oxidase domain protein
SynBIOSU31_RS00945	COG0538	isocitrate dehydrogenase activity
SynBIOSU31_RS00950	COG0463	Glycosyl transferase, family 2
SynBIOSU31_RS00965	COG5398	heme oxygenase
SynBIOSU31_RS00975	COG1132	(ABC) transporter
SynBIOSU31_RS00980	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_RS00985	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_RS00990	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_RS00995	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_RS01005	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SynBIOSU31_RS01015	COG0617	tRNA 3'-terminal CCA addition
SynBIOSU31_RS01020	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SynBIOSU31_RS01045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SynBIOSU31_RS01050	COG0124	histidyl-tRNA synthetase
SynBIOSU31_RS01120	COG1132	(ABC) transporter
SynBIOSU31_RS01155	COG2089	acid synthase
SynBIOSU31_RS01180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SynBIOSU31_RS01185	COG1086	Polysaccharide biosynthesis protein
SynBIOSU31_RS01200	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SynBIOSU31_RS01205	COG1083	cytidylyl-transferase
SynBIOSU31_RS01215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SynBIOSU31_RS01225	COG0673	inositol 2-dehydrogenase activity
SynBIOSU31_RS01230	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SynBIOSU31_RS01245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynBIOSU31_RS01280	COG1434	Gram-negative-bacterium-type cell wall biogenesis
SynBIOSU31_RS01320	COG4447	cellulose binding
SynBIOSU31_RS01325	COG1773	rubredoxin
SynBIOSU31_RS01330	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_RS01335	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_RS01340	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_RS01345	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SynBIOSU31_RS01350	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
SynBIOSU31_RS01360	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynBIOSU31_RS01360	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynBIOSU31_RS01365	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SynBIOSU31_RS01370	COG1136	(ABC) transporter
SynBIOSU31_RS01375	COG0494	nUDIX hydrolase
SynBIOSU31_RS01380	COG0415	Belongs to the DNA photolyase family
SynBIOSU31_RS01410	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SynBIOSU31_RS01415	COG0131	Imidazoleglycerol-phosphate dehydratase
SynBIOSU31_RS01420	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SynBIOSU31_RS01435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SynBIOSU31_RS01455	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynBIOSU31_RS01460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynBIOSU31_RS01470	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SynBIOSU31_RS01475	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SynBIOSU31_RS01480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynBIOSU31_RS01485	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
SynBIOSU31_RS01505	COG1253	flavin adenine dinucleotide binding
SynBIOSU31_RS01510	COG0673	inositol 2-dehydrogenase activity
SynBIOSU31_RS01530	COG0343	queuine tRNA-ribosyltransferase activity
SynBIOSU31_RS01535	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
SynBIOSU31_RS01555	COG0138	bifunctional purine biosynthesis protein purh
SynBIOSU31_RS01590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SynBIOSU31_RS01595	COG0004	ammonium transporteR
SynBIOSU31_RS01600	COG1489	DNA binding
SynBIOSU31_RS01605	COG0728	peptidoglycan biosynthetic process
SynBIOSU31_RS01630	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SynBIOSU31_RS01635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynBIOSU31_RS01640	COG1546	Belongs to the CinA family
SynBIOSU31_RS01640	COG1058	Belongs to the CinA family
SynBIOSU31_RS01645	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SynBIOSU31_RS01650	COG0066	3-isopropylmalate dehydratase activity
SynBIOSU31_RS01685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SynBIOSU31_RS01690	COG0193	aminoacyl-tRNA hydrolase activity
SynBIOSU31_RS01705	COG4372	Transposase
SynBIOSU31_RS01710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBIOSU31_RS01715	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SynBIOSU31_RS01725	COG0717	Belongs to the dCTP deaminase family
SynBIOSU31_RS01735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynBIOSU31_RS01755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SynBIOSU31_RS01770	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SynBIOSU31_RS01795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SynBIOSU31_RS01815	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynBIOSU31_RS01830	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SynBIOSU31_RS01835	COG2094	Belongs to the DNA glycosylase MPG family
SynBIOSU31_RS01840	COG0540	Belongs to the ATCase OTCase family
SynBIOSU31_RS01865	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynBIOSU31_RS01875	COG3536	Protein conserved in bacteria
SynBIOSU31_RS01880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SynBIOSU31_RS01895	COG0529	Catalyzes the synthesis of activated sulfate
SynBIOSU31_RS01895	COG2046	Belongs to the sulfate adenylyltransferase family
SynBIOSU31_RS01900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBIOSU31_RS01915	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SynBIOSU31_RS01925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
SynBIOSU31_RS01930	COG2226	methyltransferase
SynBIOSU31_RS01940	COG4176	ABC-type proline glycine betaine transport system permease component
SynBIOSU31_RS01945	COG2113	Glycine betaine
SynBIOSU31_RS01965	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynBIOSU31_RS01970	COG0436	Aminotransferase
SynBIOSU31_RS01980	COG1530	ribonuclease E activity
SynBIOSU31_RS01985	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SynBIOSU31_RS01995	COG1605	Chorismate mutase
SynBIOSU31_RS01995	COG0077	Prephenate dehydratase
SynBIOSU31_RS02000	COG2226	methyltransferase
SynBIOSU31_RS02005	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SynBIOSU31_RS02010	COG0051	transcription antitermination factor activity, RNA binding
SynBIOSU31_RS02015	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SynBIOSU31_RS02020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SynBIOSU31_RS02025	COG0049	tRNA binding
SynBIOSU31_RS02030	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SynBIOSU31_RS02045	COG0067	glutamate synthase
SynBIOSU31_RS02045	COG0069	glutamate synthase activity
SynBIOSU31_RS02045	COG0070	glutamate synthase
SynBIOSU31_RS02055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynBIOSU31_RS02075	COG2885	chlorophyll binding
SynBIOSU31_RS02080	COG2885	chlorophyll binding
SynBIOSU31_RS02115	COG0463	Glycosyl transferase, family 2
SynBIOSU31_RS02145	COG0469	pyruvate kinase activity
SynBIOSU31_RS02155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SynBIOSU31_RS02165	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SynBIOSU31_RS02175	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SynBIOSU31_RS02180	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SynBIOSU31_RS02185	COG0101	tRNA pseudouridine synthase activity
SynBIOSU31_RS02190	COG0203	ribosomal protein L17
SynBIOSU31_RS02195	COG0202	RNA polymerase activity
SynBIOSU31_RS02200	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SynBIOSU31_RS02205	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SynBIOSU31_RS02215	COG0563	adenylate kinase activity
SynBIOSU31_RS02220	COG0201	protein transport
SynBIOSU31_RS02225	COG0200	Binds to the 23S rRNA
SynBIOSU31_RS02230	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SynBIOSU31_RS02235	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SynBIOSU31_RS02240	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SynBIOSU31_RS02245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SynBIOSU31_RS02250	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SynBIOSU31_RS02255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SynBIOSU31_RS02260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SynBIOSU31_RS02265	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SynBIOSU31_RS02270	COG0255	Belongs to the universal ribosomal protein uL29 family
SynBIOSU31_RS02275	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SynBIOSU31_RS02280	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SynBIOSU31_RS02285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SynBIOSU31_RS02290	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SynBIOSU31_RS02295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SynBIOSU31_RS02300	COG0089	rRNA binding
SynBIOSU31_RS02305	COG0088	Forms part of the polypeptide exit tunnel
SynBIOSU31_RS02310	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SynBIOSU31_RS02325	COG3854	ATPases associated with a variety of cellular activities
SynBIOSU31_RS02340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SynBIOSU31_RS02370	COG3001	Fructosamine kinase
SynBIOSU31_RS02390	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SynBIOSU31_RS02395	COG1606	tRNA processing
SynBIOSU31_RS02400	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SynBIOSU31_RS02405	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SynBIOSU31_RS02420	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SynBIOSU31_RS02425	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SynBIOSU31_RS02430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SynBIOSU31_RS02445	COG0772	Belongs to the SEDS family
SynBIOSU31_RS02450	COG0489	protein tyrosine kinase activity
SynBIOSU31_RS02455	COG0408	coproporphyrinogen oxidase activity
SynBIOSU31_RS02520	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SynBIOSU31_RS02525	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SynBIOSU31_RS02530	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SynBIOSU31_RS02530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SynBIOSU31_RS02535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SynBIOSU31_RS02665	COG0237	dephospho-CoA kinase activity
SynBIOSU31_RS02690	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBIOSU31_RS02750	COG1070	Carbohydrate kinase
SynBIOSU31_RS02755	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SynBIOSU31_RS02765	COG0539	negative regulation of cytoplasmic translation
SynBIOSU31_RS02770	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SynBIOSU31_RS02805	COG0758	DNA mediated transformation
SynBIOSU31_RS02810	COG2890	protein-(glutamine-N5) methyltransferase activity
SynBIOSU31_RS02815	COG0009	L-threonylcarbamoyladenylate synthase
SynBIOSU31_RS02835	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SynBIOSU31_RS02840	COG2894	cell division
SynBIOSU31_RS02845	COG0850	regulation of cytokinetic process
SynBIOSU31_RS02850	COG1078	dGTPase activity
SynBIOSU31_RS02855	COG0793	Belongs to the peptidase S41A family
SynBIOSU31_RS02860	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynBIOSU31_RS02865	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SynBIOSU31_RS02900	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SynBIOSU31_RS02910	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SynBIOSU31_RS02930	COG0791	NLP P60 protein
SynBIOSU31_RS02930	COG1388	LysM domain
SynBIOSU31_RS02935	COG1012	belongs to the aldehyde dehydrogenase family
SynBIOSU31_RS02945	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SynBIOSU31_RS02960	COG2197	response regulator
SynBIOSU31_RS02975	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SynBIOSU31_RS02990	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SynBIOSU31_RS03010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SynBIOSU31_RS03030	COG1160	GTP binding
SynBIOSU31_RS03035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SynBIOSU31_RS03045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SynBIOSU31_RS03050	COG1799	cell septum assembly
SynBIOSU31_RS03055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SynBIOSU31_RS03065	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_RS03075	COG1381	Involved in DNA repair and RecF pathway recombination
SynBIOSU31_RS03080	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SynBIOSU31_RS03085	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SynBIOSU31_RS03090	COG0321	lipoyl(octanoyl) transferase activity
SynBIOSU31_RS03095	COG1022	Amp-dependent synthetase and ligase
SynBIOSU31_RS03105	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynBIOSU31_RS03110	COG0531	amino acid
SynBIOSU31_RS03115	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SynBIOSU31_RS03120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynBIOSU31_RS03125	COG0626	cystathionine gamma-synthase activity
SynBIOSU31_RS03165	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SynBIOSU31_RS03175	COG1104	cysteine desulfurase activity
SynBIOSU31_RS03195	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SynBIOSU31_RS03200	COG0579	oxidoreductase
SynBIOSU31_RS03215	COG3119	arylsulfatase activity
SynBIOSU31_RS03245	COG4969	Belongs to the N-Me-Phe pilin family
SynBIOSU31_RS03250	COG0481	GTPase activity
SynBIOSU31_RS03260	COG4968	Prepilin-type N-terminal cleavage methylation domain
SynBIOSU31_RS03265	COG2972	Histidine kinase
SynBIOSU31_RS03265	COG2205	protein histidine kinase activity
SynBIOSU31_RS03270	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_RS03305	COG5002	protein histidine kinase activity
SynBIOSU31_RS03310	COG4176	ABC-type proline glycine betaine transport system permease component
SynBIOSU31_RS03320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynBIOSU31_RS03325	COG0316	Belongs to the HesB IscA family
SynBIOSU31_RS03345	COG3695	enzyme binding
SynBIOSU31_RS03360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SynBIOSU31_RS03360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SynBIOSU31_RS03400	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
SynBIOSU31_RS03405	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynBIOSU31_RS03415	COG0107	imidazoleglycerol-phosphate synthase activity
SynBIOSU31_RS03425	COG2226	methyltransferase
SynBIOSU31_RS03435	COG0752	glycyl-tRNA synthetase alpha subunit
SynBIOSU31_RS03440	COG2333	competence protein COMEC
SynBIOSU31_RS03440	COG0658	competence protein
SynBIOSU31_RS03450	COG0582	viral genome integration into host DNA
SynBIOSU31_RS03515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SynBIOSU31_RS03520	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SynBIOSU31_RS03525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SynBIOSU31_RS03530	COG0740	serine-type endopeptidase activity
SynBIOSU31_RS03535	COG0740	serine-type endopeptidase activity
SynBIOSU31_RS03540	COG4956	integral membrane protein (PIN domain superfamily)
SynBIOSU31_RS03545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SynBIOSU31_RS03550	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SynBIOSU31_RS03560	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SynBIOSU31_RS03575	COG1181	Belongs to the D-alanine--D-alanine ligase family
SynBIOSU31_RS03580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynBIOSU31_RS03595	COG0402	S-adenosylhomocysteine deaminase activity
SynBIOSU31_RS03610	COG0285	dihydrofolate synthase activity
SynBIOSU31_RS03615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynBIOSU31_RS03620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SynBIOSU31_RS03625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SynBIOSU31_RS03640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynBIOSU31_RS03645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynBIOSU31_RS03650	COG0134	indole-3-glycerol-phosphate synthase activity
SynBIOSU31_RS03675	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SynBIOSU31_RS03680	COG0482	sulfurtransferase activity
SynBIOSU31_RS03685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
SynBIOSU31_RS03685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SynBIOSU31_RS03690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_RS03695	COG0123	including yeast histone deacetylase and acetoin utilization protein
SynBIOSU31_RS03700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SynBIOSU31_RS03710	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SynBIOSU31_RS03715	COG0228	four-way junction DNA binding
SynBIOSU31_RS03720	COG1702	phosphate starvation-inducible protein PhoH
SynBIOSU31_RS03740	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SynBIOSU31_RS03750	COG0336	Belongs to the RNA methyltransferase TrmD family
SynBIOSU31_RS03755	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SynBIOSU31_RS03765	COG1691	(AIR) carboxylase
SynBIOSU31_RS03785	COG0352	thiamine-phosphate diphosphorylase activity
SynBIOSU31_RS03790	COG0196	riboflavin kinase activity
SynBIOSU31_RS03800	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SynBIOSU31_RS03805	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SynBIOSU31_RS03810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynBIOSU31_RS03815	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_RS03900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SynBIOSU31_RS03905	COG3119	arylsulfatase activity
SynBIOSU31_RS03930	COG3119	arylsulfatase activity
SynBIOSU31_RS03990	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynBIOSU31_RS03990	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SynBIOSU31_RS04000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBIOSU31_RS04005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SynBIOSU31_RS04060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynBIOSU31_RS04240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynBIOSU31_RS04305	COG1742	UPF0060 membrane protein
SynBIOSU31_RS04335	COG0477	Major facilitator Superfamily
SynBIOSU31_RS04340	COG0432	Pfam Uncharacterised protein family UPF0047
SynBIOSU31_RS04365	COG1492	cobalamin metabolic process
SynBIOSU31_RS04380	COG2274	protein secretion by the type I secretion system
SynBIOSU31_RS04400	COG0424	maF-like protein
SynBIOSU31_RS04425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynBIOSU31_RS04430	COG0440	acetolactate synthase activity
SynBIOSU31_RS04435	COG2267	carboxylic ester hydrolase activity
SynBIOSU31_RS04450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynBIOSU31_RS04460	COG2226	methyltransferase
SynBIOSU31_RS04465	COG1187	pseudouridine synthase activity
SynBIOSU31_RS04475	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SynBIOSU31_RS04480	COG0492	ferredoxin-NADP+ reductase activity
SynBIOSU31_RS04510	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
SynBIOSU31_RS04525	COG3411	Ferredoxin
SynBIOSU31_RS04530	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SynBIOSU31_RS04535	COG0733	neurotransmitter:sodium symporter activity
SynBIOSU31_RS04550	COG0215	cysteine-tRNA ligase activity
SynBIOSU31_RS04560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynBIOSU31_RS04560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynBIOSU31_RS04565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SynBIOSU31_RS04570	COG0012	GTP binding
SynBIOSU31_RS04580	COG0678	peroxiredoxin activity
SynBIOSU31_RS04590	COG4095	Psort location CytoplasmicMembrane, score
SynBIOSU31_RS04610	COG0601	transmembrane transport
SynBIOSU31_RS04625	COG0460	homoserine dehydrogenase
SynBIOSU31_RS04630	COG2166	iron-sulfur cluster assembly
SynBIOSU31_RS04690	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SynBIOSU31_RS04695	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SynBIOSU31_RS04715	COG2010	Cytochrome c
SynBIOSU31_RS04725	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SynBIOSU31_RS04730	COG3118	belongs to the thioredoxin family
SynBIOSU31_RS04735	COG0516	GMP reductase activity
SynBIOSU31_RS04745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SynBIOSU31_RS04750	COG0644	oxidoreductase
SynBIOSU31_RS04755	COG1543	Belongs to the glycosyl hydrolase 57 family
SynBIOSU31_RS04760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SynBIOSU31_RS04765	COG0395	ABC-type sugar transport system, permease component
SynBIOSU31_RS04800	COG0011	TIGRFAM Protein of
SynBIOSU31_RS04815	COG0564	pseudouridine synthase activity
SynBIOSU31_RS04820	COG1480	7TM receptor with intracellular HD hydrolase
SynBIOSU31_RS04825	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SynBIOSU31_RS04830	COG0142	geranyltranstransferase activity
SynBIOSU31_RS04855	COG1254	Belongs to the acylphosphatase family
SynBIOSU31_RS04860	COG1797	cobyrinic acid a,c-diamide synthase activity
SynBIOSU31_RS04865	COG3409	Peptidoglycan-binding domain 1 protein
SynBIOSU31_RS04865	COG3429	Glucose-6-phosphate dehydrogenase subunit
SynBIOSU31_RS04870	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SynBIOSU31_RS04875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SynBIOSU31_RS04890	COG2205	protein histidine kinase activity
SynBIOSU31_RS04910	COG0308	aminopeptidase N
SynBIOSU31_RS04930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SynBIOSU31_RS04945	COG0702	epimerase
SynBIOSU31_RS04950	COG1640	4-alpha-glucanotransferase
SynBIOSU31_RS04960	COG1187	pseudouridine synthase activity
SynBIOSU31_RS04965	COG5002	protein histidine kinase activity
SynBIOSU31_RS04970	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_RS04975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_RS04985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynBIOSU31_RS04995	COG1982	Orn Lys Arg decarboxylase major
SynBIOSU31_RS05000	COG0575	Belongs to the CDS family
SynBIOSU31_RS05010	COG0596	Alpha beta hydrolase
SynBIOSU31_RS05015	COG0371	Dehydrogenase
SynBIOSU31_RS05020	COG0542	response to heat
SynBIOSU31_RS05025	COG0456	acetyltransferase
SynBIOSU31_RS05030	COG0019	diaminopimelate decarboxylase activity
SynBIOSU31_RS05035	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SynBIOSU31_RS05040	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SynBIOSU31_RS05045	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SynBIOSU31_RS05050	COG1054	Belongs to the UPF0176 family
SynBIOSU31_RS05065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SynBIOSU31_RS05070	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SynBIOSU31_RS05115	COG0475	glutathione-regulated potassium exporter activity
SynBIOSU31_RS05115	COG0589	response to stress
SynBIOSU31_RS05120	COG1132	(ABC) transporter
SynBIOSU31_RS05125	COG0724	RNA recognition motif
SynBIOSU31_RS05135	COG0513	Belongs to the DEAD box helicase family
SynBIOSU31_RS05145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SynBIOSU31_RS05150	COG1074	ATP-dependent DNA helicase activity
SynBIOSU31_RS05155	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SynBIOSU31_RS05205	COG3239	Fatty acid desaturase
SynBIOSU31_RS05415	COG1525	nuclease
SynBIOSU31_RS05460	COG2197	response regulator
SynBIOSU31_RS05530	COG4106	trans-aconitate 2-methyltransferase activity
SynBIOSU31_RS05535	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SynBIOSU31_RS05550	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SynBIOSU31_RS05555	COG1122	ATPase activity
SynBIOSU31_RS05580	COG1836	PFAM Integral membrane protein DUF92
SynBIOSU31_RS05645	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SynBIOSU31_RS05665	COG0793	Belongs to the peptidase S41A family
SynBIOSU31_RS05670	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SynBIOSU31_RS05675	COG1573	uracil-dna glycosylase
SynBIOSU31_RS05685	COG0436	Aminotransferase
SynBIOSU31_RS05690	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SynBIOSU31_RS05695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SynBIOSU31_RS05695	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SynBIOSU31_RS05700	COG3639	organic phosphonate transmembrane transporter activity
SynBIOSU31_RS05770	COG1126	abc transporter atp-binding protein
SynBIOSU31_RS05775	COG0765	amino acid transport
SynBIOSU31_RS05785	COG4597	amino acid ABC transporter
SynBIOSU31_RS05790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SynBIOSU31_RS05800	COG0659	secondary active sulfate transmembrane transporter activity
SynBIOSU31_RS05820	COG0668	transmembrane transport
SynBIOSU31_RS05840	COG0799	negative regulation of ribosome biogenesis
SynBIOSU31_RS05850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SynBIOSU31_RS05860	COG1115	amino acid carrier protein
SynBIOSU31_RS05870	COG1132	(ABC) transporter
SynBIOSU31_RS05880	COG0149	triose-phosphate isomerase activity
SynBIOSU31_RS05885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SynBIOSU31_RS05895	COG1429	ligase activity, forming nitrogen-metal bonds
SynBIOSU31_RS05900	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SynBIOSU31_RS05910	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBIOSU31_RS05925	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SynBIOSU31_RS05980	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SynBIOSU31_RS06000	COG3659	wide pore channel activity
SynBIOSU31_RS06010	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SynBIOSU31_RS06015	COG1494	fructose-1,6-bisphosphatase
SynBIOSU31_RS06020	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SynBIOSU31_RS06025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBIOSU31_RS06030	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SynBIOSU31_RS06035	COG0363	glucosamine-6-phosphate deaminase activity
SynBIOSU31_RS06050	COG0129	dihydroxy-acid dehydratase activity
SynBIOSU31_RS06060	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SynBIOSU31_RS06065	COG1357	PFAM Pentapeptide repeats (8 copies)
SynBIOSU31_RS06075	COG3895	Periplasmic Protein
SynBIOSU31_RS06090	COG1028	Short-chain dehydrogenase reductase Sdr
SynBIOSU31_RS06100	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SynBIOSU31_RS06105	COG0047	phosphoribosylformylglycinamidine synthase activity
SynBIOSU31_RS06110	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynBIOSU31_RS06120	COG0191	fructose-bisphosphate aldolase activity
SynBIOSU31_RS06125	COG3588	fructose-bisphosphate aldolase
SynBIOSU31_RS06135	COG0673	inositol 2-dehydrogenase activity
SynBIOSU31_RS06145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SynBIOSU31_RS06150	COG1528	Iron-storage protein
SynBIOSU31_RS06155	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SynBIOSU31_RS06165	COG3954	Phosphoribulokinase
SynBIOSU31_RS06170	COG0473	3-isopropylmalate dehydrogenase activity
SynBIOSU31_RS06175	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynBIOSU31_RS06185	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SynBIOSU31_RS06200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SynBIOSU31_RS06215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SynBIOSU31_RS06220	COG2197	response regulator
SynBIOSU31_RS06230	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SynBIOSU31_RS06245	COG0517	IMP dehydrogenase activity
SynBIOSU31_RS06255	COG1376	ErfK ybiS ycfS ynhG family protein
SynBIOSU31_RS06275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBIOSU31_RS06285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SynBIOSU31_RS06315	COG1119	ATPase activity
SynBIOSU31_RS06430	COG1201	RNA secondary structure unwinding
SynBIOSU31_RS06435	COG1793	dna ligase
SynBIOSU31_RS06450	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SynBIOSU31_RS06480	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SynBIOSU31_RS06490	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SynBIOSU31_RS06555	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SynBIOSU31_RS06575	COG0740	serine-type endopeptidase activity
SynBIOSU31_RS06580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBIOSU31_RS06585	COG0577	efflux transmembrane transporter activity
SynBIOSU31_RS06585	COG1136	(ABC) transporter
SynBIOSU31_RS06590	COG0469	pyruvate kinase activity
SynBIOSU31_RS06610	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SynBIOSU31_RS06615	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SynBIOSU31_RS06640	COG3842	ATPase activity
SynBIOSU31_RS06655	COG1653	transport
SynBIOSU31_RS06660	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SynBIOSU31_RS06665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynBIOSU31_RS06670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SynBIOSU31_RS06675	COG0326	Molecular chaperone. Has ATPase activity
SynBIOSU31_RS06685	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SynBIOSU31_RS06690	COG0483	inositol monophosphate 1-phosphatase activity
SynBIOSU31_RS06705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SynBIOSU31_RS06720	COG0443	Heat shock 70 kDa protein
SynBIOSU31_RS06725	COG0484	heat shock protein binding
SynBIOSU31_RS06735	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SynBIOSU31_RS06740	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SynBIOSU31_RS06745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SynBIOSU31_RS06750	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynBIOSU31_RS06750	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SynBIOSU31_RS06755	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SynBIOSU31_RS06760	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SynBIOSU31_RS06785	COG0166	Belongs to the GPI family
SynBIOSU31_RS06790	COG0495	leucyl-tRNA aminoacylation
SynBIOSU31_RS06810	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SynBIOSU31_RS06840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SynBIOSU31_RS06845	COG0322	excinuclease ABC activity
SynBIOSU31_RS06855	COG3046	protein related to deoxyribodipyrimidine photolyase
SynBIOSU31_RS06860	COG1981	membrane
SynBIOSU31_RS06865	COG0613	PHP domain protein
SynBIOSU31_RS06880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SynBIOSU31_RS06885	COG1410	methionine synthase
SynBIOSU31_RS06885	COG0646	methionine synthase
SynBIOSU31_RS06910	COG2385	sporulation resulting in formation of a cellular spore
SynBIOSU31_RS06945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SynBIOSU31_RS06950	COG0072	phenylalanine-tRNA ligase activity
SynBIOSU31_RS06955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SynBIOSU31_RS06960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SynBIOSU31_RS06965	COG0557	exoribonuclease II activity
SynBIOSU31_RS06975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SynBIOSU31_RS07010	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SynBIOSU31_RS07015	COG0739	heme binding
SynBIOSU31_RS07030	COG0450	alkyl hydroperoxide reductase
SynBIOSU31_RS07035	COG1615	UPF0182 protein
SynBIOSU31_RS07040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBIOSU31_RS07045	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SynBIOSU31_RS07060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynBIOSU31_RS07065	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SynBIOSU31_RS07065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SynBIOSU31_RS07085	COG2119	membrane
SynBIOSU31_RS07095	COG0557	exoribonuclease II activity
SynBIOSU31_RS07100	COG0163	prenyltransferase activity
SynBIOSU31_RS07115	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SynBIOSU31_RS07120	COG0312	modulator of DNA gyrase
SynBIOSU31_RS07130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SynBIOSU31_RS07135	COG0513	Belongs to the DEAD box helicase family
SynBIOSU31_RS07150	COG0861	Integral membrane protein TerC family
SynBIOSU31_RS07165	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SynBIOSU31_RS07180	COG0271	Belongs to the BolA IbaG family
SynBIOSU31_RS07185	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SynBIOSU31_RS07190	COG0596	Alpha beta hydrolase
SynBIOSU31_RS07200	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_RS07215	COG0076	glutamate decarboxylase activity
SynBIOSU31_RS07220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynBIOSU31_RS07235	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SynBIOSU31_RS07255	COG4565	transcriptional regulatory protein
SynBIOSU31_RS07305	COG0735	belongs to the Fur family
SynBIOSU31_RS07315	COG1799	cell septum assembly
SynBIOSU31_RS07390	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SynBIOSU31_RS07415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SynBIOSU31_RS07440	COG1217	gtp-binding protein TYPA
SynBIOSU31_RS07450	COG0644	oxidoreductase
SynBIOSU31_RS07455	COG0751	glycine-tRNA ligase activity
SynBIOSU31_RS07460	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynBIOSU31_RS07465	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SynBIOSU31_RS07470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SynBIOSU31_RS07480	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SynBIOSU31_RS07485	COG0052	Belongs to the universal ribosomal protein uS2 family
SynBIOSU31_RS07490	COG1216	Glycosyl transferase, family 2
SynBIOSU31_RS07520	COG0612	Peptidase, M16
SynBIOSU31_RS07540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SynBIOSU31_RS07545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SynBIOSU31_RS07565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SynBIOSU31_RS07575	COG0174	glutamine synthetase
SynBIOSU31_RS07590	COG2226	methyltransferase
SynBIOSU31_RS07610	COG0515	serine threonine protein kinase
SynBIOSU31_RS07615	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SynBIOSU31_RS07625	COG0628	permease
SynBIOSU31_RS07650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynBIOSU31_RS07655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SynBIOSU31_RS07660	COG0508	dehydrogenase complex catalyzes the overall conversion of
SynBIOSU31_RS07660	COG0022	dehydrogenase e1 component
SynBIOSU31_RS07670	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SynBIOSU31_RS07675	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SynBIOSU31_RS07700	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SynBIOSU31_RS07715	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SynBIOSU31_RS07855	COG1028	Short-chain dehydrogenase reductase Sdr
SynBIOSU31_RS07865	COG0358	DNA primase activity
SynBIOSU31_RS07870	COG1566	PFAM secretion protein HlyD family protein
SynBIOSU31_RS07880	COG0577	efflux transmembrane transporter activity
SynBIOSU31_RS07880	COG1136	(ABC) transporter
SynBIOSU31_RS07905	COG0632	four-way junction helicase activity
SynBIOSU31_RS07910	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SynBIOSU31_RS07920	COG0587	DNA-directed DNA polymerase activity
SynBIOSU31_RS07925	COG0154	amidase activity
SynBIOSU31_RS07935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SynBIOSU31_RS07940	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SynBIOSU31_RS07950	COG0505	Belongs to the CarA family
SynBIOSU31_RS07955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynBIOSU31_RS07960	COG1132	(ABC) transporter
SynBIOSU31_RS07970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynBIOSU31_RS07990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBIOSU31_RS08005	COG2176	DNA-directed DNA polymerase activity
SynBIOSU31_RS08010	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynBIOSU31_RS08025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SynBIOSU31_RS08030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SynBIOSU31_RS08035	COG0142	geranyltranstransferase activity
SynBIOSU31_RS08040	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SynBIOSU31_RS08055	COG2045	Belongs to the ComB family
SynBIOSU31_RS08060	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SynBIOSU31_RS08065	COG1840	ABC-type Fe3 transport system, periplasmic component
SynBIOSU31_RS08070	COG3128	pkhd-type hydroxylase
SynBIOSU31_RS08080	COG3659	wide pore channel activity
SynBIOSU31_RS08085	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SynBIOSU31_RS08100	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SynBIOSU31_RS08105	COG1597	lipid kinase activity
SynBIOSU31_RS08105	COG1803	Methylglyoxal synthase
SynBIOSU31_RS08120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SynBIOSU31_RS08130	COG0297	glycogen (starch) synthase activity
SynBIOSU31_RS08135	COG1376	ErfK ybiS ycfS ynhG family protein
SynBIOSU31_RS08140	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SynBIOSU31_RS08145	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SynBIOSU31_RS08150	COG0681	Belongs to the peptidase S26 family
SynBIOSU31_RS08185	COG0277	FAD linked oxidase domain protein
SynBIOSU31_RS08225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SynBIOSU31_RS08235	COG3119	arylsulfatase activity
SynBIOSU31_RS08370	COG0803	Belongs to the bacterial solute-binding protein 9 family
SynBIOSU31_RS08375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynBIOSU31_RS08380	COG1121	(ABC) transporter
SynBIOSU31_RS08395	COG0701	Predicted permease
SynBIOSU31_RS08415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynBIOSU31_RS08420	COG1121	(ABC) transporter
SynBIOSU31_RS08525	COG2032	superoxide dismutase activity
SynBIOSU31_RS08530	COG0717	Belongs to the dCTP deaminase family
SynBIOSU31_RS08790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SynBIOSU31_RS08795	COG0300	oxidoreductase activity
SynBIOSU31_RS08835	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SynBIOSU31_RS08880	COG2234	aminopeptidase activity
SynBIOSU31_RS08965	COG2720	vancomycin resistance protein
SynBIOSU31_RS08975	COG0523	cobalamin synthesis protein
SynBIOSU31_RS08985	COG1121	(ABC) transporter
SynBIOSU31_RS08990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SynBIOSU31_RS08995	COG2124	cytochrome p450
SynBIOSU31_RS09070	COG0484	heat shock protein binding
SynBIOSU31_RS09270	COG2135	peptidase activity
SynBIOSU31_RS09300	COG2084	Dehydrogenase
SynBIOSU31_RS09310	COG0515	serine threonine protein kinase
SynBIOSU31_RS09365	COG3781	membrane
SynBIOSU31_RS09420	COG1233	COG1233 Phytoene dehydrogenase and related
SynBIOSU31_RS09470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SynBIOSU31_RS09475	COG0351	phosphomethylpyrimidine kinase
SynBIOSU31_RS09515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SynBIOSU31_RS09555	COG0180	Tryptophanyl-tRNA synthetase
SynBIOSU31_RS09580	COG0837	glucose binding
SynBIOSU31_RS09585	COG0083	homoserine kinase activity
SynBIOSU31_RS09590	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_RS09595	COG0339	signal peptide processing
SynBIOSU31_RS09625	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SynBIOSU31_RS09630	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SynBIOSU31_RS09670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SynBIOSU31_RS09675	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SynBIOSU31_RS09685	COG3794	PFAM blue (type 1) copper domain protein
SynBIOSU31_RS09730	COG0542	response to heat
SynBIOSU31_RS09740	COG0140	phosphoribosyl-ATP diphosphatase activity
SynBIOSU31_RS09740	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SynBIOSU31_RS09745	COG1376	ErfK ybiS ycfS ynhG family protein
SynBIOSU31_RS09760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_RS09765	COG3339	Conserved Protein
SynBIOSU31_RS09790	COG2010	Cytochrome c
SynBIOSU31_RS09805	COG0159	tryptophan synthase activity
SynBIOSU31_RS09830	COG0418	dihydroorotase activity
SynBIOSU31_RS09835	COG0659	secondary active sulfate transmembrane transporter activity
SynBIOSU31_RS09840	COG0530	calcium, potassium:sodium antiporter activity
SynBIOSU31_RS09860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SynBIOSU31_RS09875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SynBIOSU31_RS09890	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SynBIOSU31_RS09895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynBIOSU31_RS09910	COG0456	acetyltransferase
SynBIOSU31_RS09915	COG0596	Alpha beta hydrolase
SynBIOSU31_RS09920	COG1132	(ABC) transporter
SynBIOSU31_RS09925	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SynBIOSU31_RS09930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SynBIOSU31_RS09935	COG3842	ATPase activity
SynBIOSU31_RS09940	COG0251	oxidation-reduction process
SynBIOSU31_RS09965	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_RS09970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynBIOSU31_RS09975	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynBIOSU31_RS10000	COG4451	ribulose bisphosphate carboxylase, small
SynBIOSU31_RS10005	COG1850	ribulose-bisphosphate carboxylase activity
SynBIOSU31_RS10010	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynBIOSU31_RS10015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SynBIOSU31_RS10020	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SynBIOSU31_RS10035	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynBIOSU31_RS10040	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SynBIOSU31_RS10045	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SynBIOSU31_RS10075	COG0730	response to heat
SynBIOSU31_RS10080	COG0095	Lipoate-protein ligase
SynBIOSU31_RS10085	COG0517	IMP dehydrogenase activity
SynBIOSU31_RS10085	COG1994	Peptidase M50
SynBIOSU31_RS10090	COG0135	phosphoribosylanthranilate isomerase activity
SynBIOSU31_RS10100	COG0302	gtp cyclohydrolase
SynBIOSU31_RS10105	COG1028	Short-chain dehydrogenase reductase Sdr
SynBIOSU31_RS10110	COG0825	malonyl-CoA metabolic process
SynBIOSU31_RS10115	COG5322	oxidoreductase activity
SynBIOSU31_RS10120	COG3396	Phenylacetate-CoA oxygenase
SynBIOSU31_RS10130	COG0539	negative regulation of cytoplasmic translation
SynBIOSU31_RS10145	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SynBIOSU31_RS10160	COG0028	Belongs to the TPP enzyme family
SynBIOSU31_RS10165	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBIOSU31_RS10175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SynBIOSU31_RS10180	COG2226	methyltransferase
SynBIOSU31_RS10195	COG0528	UMP kinase activity
SynBIOSU31_RS10200	COG0233	cytoplasmic translational termination
SynBIOSU31_RS10205	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
SynBIOSU31_RS10210	COG0415	Belongs to the DNA photolyase family
SynBIOSU31_RS10220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SynBIOSU31_RS10225	COG0768	penicillin binding
SynBIOSU31_RS10245	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SynBIOSU31_RS10250	COG0681	Belongs to the peptidase S26 family
SynBIOSU31_RS10270	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynBIOSU31_RS10280	COG0442	prolyl-tRNA aminoacylation
SynBIOSU31_RS10290	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SynBIOSU31_RS10295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SynBIOSU31_RS10305	COG2099	Precorrin-6x reductase
SynBIOSU31_RS10310	COG0629	single-stranded DNA binding
SynBIOSU31_RS10325	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SynBIOSU31_RS10335	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SynBIOSU31_RS10340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_RS10350	COG0181	hydroxymethylbilane synthase activity
SynBIOSU31_RS10355	COG2095	MarC family integral membrane protein
SynBIOSU31_RS10370	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SynBIOSU31_RS10375	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SynBIOSU31_RS10395	COG2154	pterin-4-alpha-carbinolamine dehydratase
SynBIOSU31_RS10400	COG0523	cobalamin synthesis protein
SynBIOSU31_RS10420	COG1230	cation diffusion facilitator family transporter
SynBIOSU31_RS10430	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SynBIOSU31_RS10460	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SynBIOSU31_RS10470	COG1666	GTP binding
SynBIOSU31_RS10480	COG0330	HflC and HflK could
SynBIOSU31_RS10495	COG0857	belongs to the CobB CobQ family
SynBIOSU31_RS10505	COG3000	fatty acid hydroxylase
SynBIOSU31_RS10505	COG0300	oxidoreductase activity
SynBIOSU31_RS10510	COG0024	Methionine aminopeptidase
SynBIOSU31_RS10520	COG0335	large ribosomal subunit rRNA binding
SynBIOSU31_RS10540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynBIOSU31_RS10545	COG3263	regulation of cellular component size
SynBIOSU31_RS10560	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SynBIOSU31_RS10575	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBIOSU31_RS10580	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SynBIOSU31_RS10595	COG0194	GDP metabolic process
SynBIOSU31_RS10605	COG0805	protein transport
SynBIOSU31_RS10615	COG0723	plastoquinol--plastocyanin reductase activity
SynBIOSU31_RS10620	COG0739	heme binding
SynBIOSU31_RS10625	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SynBIOSU31_RS10665	COG0248	Ppx GppA phosphatase
SynBIOSU31_RS10670	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SynBIOSU31_RS10675	COG1619	proteins homologs of microcin C7 resistance protein MccF
SynBIOSU31_RS10680	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SynBIOSU31_RS10690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SynBIOSU31_RS10695	COG1028	Short-chain dehydrogenase reductase Sdr
SynBIOSU31_RS10700	COG0459	protein refolding
SynBIOSU31_RS10710	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SynBIOSU31_RS10730	COG0109	protoheme IX farnesyltransferase activity
SynBIOSU31_RS10735	COG1612	heme a metabolic process
SynBIOSU31_RS10750	COG1845	cytochrome c oxidase, subunit III
SynBIOSU31_RS10785	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SynBIOSU31_RS10800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SynBIOSU31_RS10805	COG1007	ATP synthesis coupled electron transport
SynBIOSU31_RS10810	COG1136	(ABC) transporter
SynBIOSU31_RS10810	COG0577	efflux transmembrane transporter activity
SynBIOSU31_RS10815	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_RS10820	COG0739	heme binding
SynBIOSU31_RS10825	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SynBIOSU31_RS10825	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SynBIOSU31_RS10830	COG0436	Aminotransferase
SynBIOSU31_RS10835	COG1842	Phage shock protein A
SynBIOSU31_RS10845	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SynBIOSU31_RS10855	COG0697	spore germination
SynBIOSU31_RS10860	COG0616	signal peptide processing
SynBIOSU31_RS10880	COG0594	ribonuclease P activity
SynBIOSU31_RS10890	COG0706	membrane insertase activity
SynBIOSU31_RS10900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SynBIOSU31_RS10910	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SynBIOSU31_RS10915	COG0750	zinc metalloprotease
SynBIOSU31_RS10920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SynBIOSU31_RS10925	COG1185	polyribonucleotide nucleotidyltransferase activity
SynBIOSU31_RS10930	COG1218	3'(2'),5'-bisphosphate nucleotidase
SynBIOSU31_RS10935	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SynBIOSU31_RS11130	COG0039	L-malate dehydrogenase activity
SynBIOSU31_RS11255	COG1970	mechanosensitive ion channel activity
SynBIOSU31_RS11270	COG0625	glutathione transferase activity
SynBIOSU31_RS11355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SynBIOSU31_RS11360	COG0776	regulation of translation
SynBIOSU31_RS11380	COG2211	Major facilitator Superfamily
SynBIOSU31_RS11385	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SynBIOSU31_RS11400	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SynBIOSU31_RS11405	COG0284	orotidine-5'-phosphate decarboxylase activity
SynBIOSU31_RS11410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SynBIOSU31_RS11435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SynBIOSU31_RS11445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynBIOSU31_RS11445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynBIOSU31_RS11455	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SynBIOSU31_RS11460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SynBIOSU31_RS11465	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SynBIOSU31_RS11475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SynBIOSU31_RS11485	COG0151	Belongs to the GarS family
SynBIOSU31_RS11490	COG5002	protein histidine kinase activity
SynBIOSU31_RS11495	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SynBIOSU31_RS11500	COG4251	negative regulation of phosphorylation
SynBIOSU31_RS11510	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SynBIOSU31_RS11515	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SynBIOSU31_RS11525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynBIOSU31_RS11530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SynBIOSU31_RS11535	COG0217	transcriptional regulatory protein
SynBIOSU31_RS11545	COG0363	glucosamine-6-phosphate deaminase activity
SynBIOSU31_RS11550	COG2385	sporulation resulting in formation of a cellular spore
SynBIOSU31_RS11555	COG1234	tRNA 3'-trailer cleavage
SynBIOSU31_RS11560	COG2010	Cytochrome c
SynBIOSU31_RS11575	COG2264	protein methyltransferase activity
SynBIOSU31_RS11580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SynBIOSU31_RS11600	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SynBIOSU31_RS11645	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SynBIOSU31_RS11660	COG0004	ammonium transporteR
SynBIOSU31_RS11665	COG0459	protein refolding
SynBIOSU31_RS11670	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SynBIOSU31_RS11675	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SynBIOSU31_RS11680	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SynBIOSU31_RS11685	COG0739	heme binding
SynBIOSU31_RS11700	COG0006	proline dipeptidase activity
SynBIOSU31_RS11705	COG1253	flavin adenine dinucleotide binding
SynBIOSU31_RS11710	COG1160	GTP binding
SynBIOSU31_RS11715	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SynBIOSU31_RS11720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynBIOSU31_RS11720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SynBIOSU31_RS11730	COG3012	SEC-C Motif Domain Protein
SynBIOSU31_RS11735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SynBIOSU31_RS11745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SynBIOSU31_RS11750	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SynBIOSU31_RS11755	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SynBIOSU31_RS11760	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynBIOSU31_RS11765	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynBIOSU31_RS11770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SynBIOSU31_RS11775	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SynBIOSU31_RS11780	COG0356	it plays a direct role in the translocation of protons across the membrane
SynBIOSU31_RS11790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynBIOSU31_RS11795	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBIOSU31_RS11815	COG0772	Belongs to the SEDS family
SynBIOSU31_RS11825	COG1333	cytochrome c biogenesis protein
SynBIOSU31_RS11830	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SynBIOSU31_RS11845	COG0347	Belongs to the P(II) protein family
SynBIOSU31_RS11860	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SynBIOSU31_RS11870	COG0114	fumarate hydratase activity
SynBIOSU31_RS11875	COG4581	dead DEAH box helicase
SynBIOSU31_RS11880	COG0156	8-amino-7-oxononanoate synthase activity
SynBIOSU31_RS11895	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SynBIOSU31_RS11895	COG4106	trans-aconitate 2-methyltransferase activity
SynBIOSU31_RS11910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SynBIOSU31_RS11925	COG0357	Ribosomal RNA small subunit methyltransferase G
SynBIOSU31_RS11955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SynBIOSU31_RS11960	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SynBIOSU31_RS11965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBIOSU31_RS11970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynBIOSU31_RS11975	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SynBIOSU31_RS11980	COG0085	RNA polymerase activity
SynBIOSU31_RS11985	COG0084	hydrolase, TatD family'
SynBIOSU31_RS11990	COG0268	Binds directly to 16S ribosomal RNA
SynBIOSU31_RS11995	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SynBIOSU31_RS12000	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SynBIOSU31_RS12005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynBIOSU31_RS12020	COG0641	radical SAM
SynBIOSU31_RS12025	COG0779	Required for maturation of 30S ribosomal subunits
SynBIOSU31_RS12030	COG0195	Participates in both transcription termination and antitermination
SynBIOSU31_RS12040	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SynBIOSU31_RS12105	COG2988	succinylglutamate desuccinylase activity
SynBIOSU31_RS12110	COG0435	Glutathione S-transferase
SynBIOSU31_RS12120	COG0488	(ABC) transporter
SynBIOSU31_RS12135	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SynBIOSU31_RS12140	COG3842	ATPase activity
SynBIOSU31_RS12145	COG1193	negative regulation of DNA recombination
SynBIOSU31_RS12155	COG0113	porphobilinogen synthase activity
SynBIOSU31_RS12160	COG0484	heat shock protein binding
SynBIOSU31_RS12170	COG0659	secondary active sulfate transmembrane transporter activity
SynBIOSU31_RS12185	COG0492	ferredoxin-NADP+ reductase activity
SynBIOSU31_RS12465	COG0116	Belongs to the methyltransferase superfamily
SynBIOSU31_RS12485	COG1196	nuclear chromosome segregation
SynBIOSU31_RS12495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SynBIOSU31_RS12510	COG0439	Biotin carboxylase
SynBIOSU31_RS12525	COG0515	serine threonine protein kinase
SynBIOSU31_RS12545	COG4178	(ABC) transporter
SynBIOSU31_RS12550	COG0537	adenosine 5'-monophosphoramidase activity
SynBIOSU31_RS12565	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SynBIOSU31_RS12580	COG0242	peptide deformylase activity
SynBIOSU31_RS12590	COG0235	Class ii aldolase
SynBIOSU31_RS12595	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SynBIOSU31_RS12600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SynBIOSU31_RS12605	COG0719	Fe-S assembly protein
SynBIOSU31_RS12610	COG0396	ATPase activity
SynBIOSU31_RS12615	COG0719	Fe-S assembly protein
SynBIOSU31_RS12635	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBIOSU31_RS12655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SynBIOSU31_RS12685	COG0033	Phosphoglucomutase
SynBIOSU31_RS12695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SynBIOSU31_RS12705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SynBIOSU31_RS12720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SynBIOSU31_RS12725	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SynBIOSU31_RS12730	COG0175	sulfate reduction
SynBIOSU31_RS12735	COG1252	NADH dehydrogenase
SynBIOSU31_RS12740	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SynBIOSU31_RS12745	COG0471	metal ion transport
SynBIOSU31_RS12745	COG3273	potassium ion transport
SynBIOSU31_RS12750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SynBIOSU31_RS12755	COG0569	domain protein
SynBIOSU31_RS12760	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SynBIOSU31_RS12785	COG0488	(ABC) transporter
SynBIOSU31_RS12795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SynBIOSU31_RS12810	COG1643	Atp-dependent helicase
SynBIOSU31_RS12825	COG1570	exodeoxyribonuclease VII activity
SynBIOSU31_RS12875	COG0483	inositol monophosphate 1-phosphatase activity
SynBIOSU31_RS12890	COG1968	undecaprenyl-diphosphatase activity
SynBIOSU31_RS12900	COG1555	photosystem II stabilization
SynBIOSU31_RS12905	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SynBIOSU31_RS12910	COG4243	Vitamin k epoxide reductase
SynBIOSU31_RS12915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SynBIOSU31_RS12930	COG1032	radical SAM domain protein
SynBIOSU31_RS12960	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SynBIOSU31_RS12990	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SynBIOSU31_RS12995	COG1472	Belongs to the glycosyl hydrolase 3 family
SynBIOSU31_RS13000	COG0457	Tetratricopeptide repeat
SynBIOSU31_RS13000	COG0463	Glycosyl transferase, family 2
SynBIOSU31_RS13005	COG1587	Uroporphyrinogen-III synthase
SynBIOSU31_RS13020	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynBIOSU31_RS13025	COG0316	Belongs to the HesB IscA family
SynBIOSU31_RS13045	COG1090	epimerase
SynBIOSU31_RS13050	COG3263	regulation of cellular component size
SynBIOSU31_RS13065	COG0484	heat shock protein binding
SynBIOSU31_RS13070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SynBIOSU31_RS13075	COG3659	wide pore channel activity
SynBIOSU31_RS13120	COG1122	ATPase activity
SynBIOSU31_RS13130	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_RS13140	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SynBIOSU31_RS13145	COG2217	Heavy metal translocating P-type atpase
SynBIOSU31_RS13150	COG3063	Type IV pilus biogenesis stability protein PilW
SynBIOSU31_RS13155	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SynBIOSU31_RS13165	COG0416	fatty acid biosynthetic process
SynBIOSU31_RS13170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SynBIOSU31_RS13175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SynBIOSU31_RS13180	COG0204	Acyl-transferase
SynBIOSU31_RS13180	COG0318	PFAM AMP-dependent synthetase and ligase
SynBIOSU31_RS13190	COG1214	PFAM Peptidase M22, glycoprotease
SynBIOSU31_RS13200	COG0617	tRNA 3'-terminal CCA addition
SynBIOSU31_RS13210	COG1562	ergosterol biosynthetic process
SynBIOSU31_RS13215	COG0493	'glutamate synthase
SynBIOSU31_RS13215	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SynBIOSU31_RS13230	COG0583	DNA-binding transcription factor activity
SynBIOSU31_RS13240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SynBIOSU31_RS13245	COG3659	wide pore channel activity
SynBIOSU31_RS13250	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_RS13260	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SynBIOSU31_RS13270	COG2197	response regulator
SynBIOSU31_RS13280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SynBIOSU31_RS13285	COG0713	ATP synthesis coupled electron transport
SynBIOSU31_RS13290	COG0839	Belongs to the complex I subunit 6 family
SynBIOSU31_RS13295	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SynBIOSU31_RS13300	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SynBIOSU31_RS13305	COG0372	Belongs to the citrate synthase family
SynBIOSU31_RS13325	COG1420	regulation of RNA biosynthetic process
SynBIOSU31_RS13330	COG0133	tryptophan synthase activity
SynBIOSU31_RS13340	COG0023	Translation Initiation Factor
SynBIOSU31_RS13345	COG0529	Catalyzes the synthesis of activated sulfate
SynBIOSU31_RS13350	COG0628	permease
SynBIOSU31_RS13355	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SynBIOSU31_RS13360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SynBIOSU31_RS13365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SynBIOSU31_RS13375	COG0564	pseudouridine synthase activity
SynBIOSU31_RS13380	COG0745	RESPONSE REGULATOR receiver
SynBIOSU31_RS13390	COG1104	cysteine desulfurase activity
SynBIOSU31_RS13400	COG0275	rRNA processing
SynBIOSU31_RS13405	COG0649	NAD binding
SynBIOSU31_RS13415	COG0824	Thioesterase
SynBIOSU31_RS13430	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SynBIOSU31_RS13445	COG1575	Belongs to the MenA family. Type 1 subfamily
SynBIOSU31_RS13460	COG0189	ligase activity
SynBIOSU31_RS13465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SynBIOSU31_RS13480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SynBIOSU31_RS13485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SynBIOSU31_RS13490	COG0512	Glutamine amidotransferase of anthranilate synthase
SynBIOSU31_RS13500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynBIOSU31_RS13510	COG0252	asparaginase activity
SynBIOSU31_RS13515	COG0018	arginyl-trna synthetase
SynBIOSU31_RS13520	COG0157	Belongs to the NadC ModD family
SynBIOSU31_RS13525	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SynBIOSU31_RS13535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SynBIOSU31_RS13540	COG4172	Belongs to the ABC transporter superfamily
SynBIOSU31_RS13560	COG0564	pseudouridine synthase activity
SynBIOSU31_RS13570	COG0589	response to stress
SynBIOSU31_RS13575	COG0126	phosphoglycerate kinase activity
SynBIOSU31_RS13620	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SynBIOSU31_RS13625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SynBIOSU31_RS13635	COG1450	Type ii and iii secretion system protein
SynBIOSU31_RS13655	COG0167	dihydroorotate dehydrogenase activity
SynBIOSU31_RS13660	COG0328	RNA-DNA hybrid ribonuclease activity
SynBIOSU31_RS13670	COG0222	ribosome binding
SynBIOSU31_RS13675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SynBIOSU31_RS13680	COG0081	regulation of translation
SynBIOSU31_RS13685	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SynBIOSU31_RS13690	COG0250	Participates in transcription elongation, termination and antitermination
SynBIOSU31_RS13695	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SynBIOSU31_RS13700	COG0542	response to heat
SynBIOSU31_RS13705	COG0346	lactoylglutathione lyase activity
SynBIOSU31_RS13710	COG0148	phosphopyruvate hydratase activity
SynBIOSU31_RS13715	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynBIOSU31_RS13730	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SynBIOSU31_RS13735	COG0237	dephospho-CoA kinase activity
SynBIOSU31_RS13750	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SynBIOSU31_RS13755	COG2022	thiamine diphosphate biosynthetic process
SynBIOSU31_RS13755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SynBIOSU31_RS13760	COG0105	UTP biosynthetic process
SynBIOSU31_RS13765	COG1166	arginine decarboxylase activity
SynBIOSU31_RS13770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SynBIOSU31_RS13810	COG1803	Methylglyoxal synthase
SynBIOSU31_RS13815	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
SynBIOSU31_RS13830	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SynBIOSU31_RS13840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SynBIOSU31_RS13860	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
SynBIOSU31_RS13870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
SynBIOSU31_RS13875	COG0426	domain, Protein
SynBIOSU31_RS13875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynBIOSU31_RS13885	COG0426	domain, Protein
SynBIOSU31_RS13885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SynBIOSU31_RS13910	COG0509	glycine decarboxylation via glycine cleavage system
SynBIOSU31_RS13915	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SynBIOSU31_RS13935	COG0359	binds to the 23S rRNA
SynBIOSU31_RS13940	COG1372	Participates in initiation and elongation during chromosome replication
SynBIOSU31_RS13940	COG0305	Participates in initiation and elongation during chromosome replication
SynBIOSU31_RS13940	COG0305	Participates in initiation and elongation during chromosome replication
SynBIOSU31_RS13940	COG1372	Participates in initiation and elongation during chromosome replication
SynBIOSU31_RS13965	COG0445	tRNA wobble uridine modification
SynBIOSU31_RS14005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SynBIOSU31_RS14020	COG0398	Pfam SNARE associated Golgi protein
SynBIOSU31_RS14030	COG0668	transmembrane transport
SynBIOSU31_RS14035	COG0668	transmembrane transport
SynBIOSU31_RS14060	COG1131	(ABC) transporter
SynBIOSU31_RS14065	COG0525	valine-tRNA ligase activity
SynBIOSU31_RS14075	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
SynBIOSU31_RS14075	COG3264	Mechanosensitive ion channel
SynBIOSU31_RS14095	COG4221	oxidoreductase activity
SynBIOSU31_RS14120	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBIOSU31_RS14160	COG5002	protein histidine kinase activity
SynBIOSU31_RS14185	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SynBIOSU31_RS14200	COG3956	TIGRFAM MazG family protein
SynBIOSU31_RS14205	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SynBIOSU31_RS14230	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SynBIOSU31_RS14235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SynBIOSU31_RS14240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_RS14245	COG0783	Belongs to the Dps family
SynBIOSU31_RS14250	COG0504	CTP synthase activity
SynBIOSU31_RS14255	COG0602	queuosine metabolic process
SynBIOSU31_RS14260	COG4942	peptidase
SynBIOSU31_RS14265	COG4574	serine-type endopeptidase inhibitor activity
SynBIOSU31_RS14270	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SynBIOSU31_RS14285	COG3769	mannosylglycerate metabolic process
SynBIOSU31_RS14290	COG0366	Alpha amylase catalytic
SynBIOSU31_RS14300	COG0804	urea catabolic process
SynBIOSU31_RS14305	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SynBIOSU31_RS14305	COG0519	Catalyzes the synthesis of GMP from XMP
SynBIOSU31_RS14320	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SynBIOSU31_RS14325	COG0746	molybdenum cofactor guanylyltransferase activity
SynBIOSU31_RS14330	COG2223	nitrite transmembrane transporter activity
SynBIOSU31_RS14335	COG0243	molybdopterin cofactor binding
SynBIOSU31_RS14350	COG0315	cyclic pyranopterin monophosphate synthase activity
SynBIOSU31_RS14355	COG0303	'Molybdopterin
SynBIOSU31_RS14360	COG0314	molybdopterin synthase activity
SynBIOSU31_RS14365	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SynBIOSU31_RS14370	COG0521	Mo-molybdopterin cofactor biosynthetic process
SynBIOSU31_RS14375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SynBIOSU31_RS14390	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SynBIOSU31_RS14395	COG2116	formate transmembrane transporter activity
SynBIOSU31_RS14405	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SynBIOSU31_RS14415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SynBIOSU31_RS14430	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SynBIOSU31_RS14435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SynBIOSU31_RS14440	COG0170	dolichyl monophosphate biosynthetic process
SynBIOSU31_RS14445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SynBIOSU31_RS14450	COG1049	propionate catabolic process, 2-methylcitrate cycle
SynBIOSU31_RS14470	COG0788	formyltetrahydrofolate deformylase activity
SynBIOSU31_RS14495	COG0443	Heat shock 70 kDa protein
SynBIOSU31_RS14500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SynBIOSU31_RS14510	COG0360	Binds together with S18 to 16S ribosomal RNA
SynBIOSU31_RS14520	COG0137	argininosuccinate synthase activity
SynBIOSU31_RS14535	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SynBIOSU31_RS14550	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SynBIOSU31_RS14555	COG0438	transferase activity, transferring glycosyl groups
SynBIOSU31_RS14565	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SynBIOSU31_RS14570	COG0497	DNA recombination
SynBIOSU31_RS14575	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SynBIOSU31_RS14585	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine