locus-tag	class	description
CB0101_RS00005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CB0101_RS00055	COG2010	Cytochrome c
CB0101_RS00075	COG0159	tryptophan synthase activity
CB0101_RS00110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CB0101_RS00115	COG1845	cytochrome c oxidase, subunit III
CB0101_RS00215	COG1840	ABC-type Fe3 transport system, periplasmic component
CB0101_RS00235	COG0730	response to heat
CB0101_RS00240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CB0101_RS00275	COG2267	carboxylic ester hydrolase activity
CB0101_RS00295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CB0101_RS00310	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CB0101_RS00325	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CB0101_RS00345	COG3604	Transcriptional regulator
CB0101_RS00375	COG2226	methyltransferase
CB0101_RS00390	COG0351	phosphomethylpyrimidine kinase
CB0101_RS00410	COG0367	asparagine synthase
CB0101_RS00415	COG0540	Belongs to the ATCase OTCase family
CB0101_RS00440	COG0028	Belongs to the TPP enzyme family
CB0101_RS00445	COG3527	Alpha-acetolactate decarboxylase
CB0101_RS00460	COG0402	S-adenosylhomocysteine deaminase activity
CB0101_RS00475	COG0477	Major facilitator Superfamily
CB0101_RS00480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CB0101_RS00505	COG2226	methyltransferase
CB0101_RS00515	COG3039	Transposase
CB0101_RS00545	COG2326	polyphosphate kinase activity
CB0101_RS00565	COG0745	RESPONSE REGULATOR receiver
CB0101_RS00680	COG1215	transferase activity, transferring glycosyl groups
CB0101_RS00690	COG3706	GGDEF domain
CB0101_RS00785	COG3039	Transposase
CB0101_RS00815	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CB0101_RS00860	COG0659	secondary active sulfate transmembrane transporter activity
CB0101_RS00910	COG0799	negative regulation of ribosome biogenesis
CB0101_RS00920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CB0101_RS00930	COG1115	amino acid carrier protein
CB0101_RS00950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CB0101_RS00955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CB0101_RS01000	COG0237	dephospho-CoA kinase activity
CB0101_RS01010	COG0418	dihydroorotase activity
CB0101_RS01015	COG1872	DUF167
CB0101_RS01020	COG5001	Diguanylate cyclase
CB0101_RS01020	COG1716	ATPase activity
CB0101_RS01075	COG0709	Synthesizes selenophosphate from selenide and ATP
CB0101_RS01085	COG2197	response regulator
CB0101_RS01150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CB0101_RS01155	COG0640	Transcriptional regulator
CB0101_RS01160	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CB0101_RS01170	COG0745	RESPONSE REGULATOR receiver
CB0101_RS01175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CB0101_RS01180	COG0573	inorganic phosphate transmembrane transporter activity
CB0101_RS01185	COG0581	inorganic phosphate transmembrane transporter activity
CB0101_RS01190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CB0101_RS01200	COG3039	Transposase
CB0101_RS01225	COG0671	phosphoesterase, PA-phosphatase related
CB0101_RS01230	COG1252	NADH dehydrogenase
CB0101_RS01235	COG2271	Major facilitator Superfamily
CB0101_RS01240	COG0058	SHG alpha-glucan phosphorylase activity
CB0101_RS01245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CB0101_RS01270	COG0598	Magnesium transport protein CorA
CB0101_RS01290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CB0101_RS01295	COG5002	protein histidine kinase activity
CB0101_RS01300	COG0745	RESPONSE REGULATOR receiver
CB0101_RS01325	COG1741	Belongs to the pirin family
CB0101_RS01345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CB0101_RS01360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CB0101_RS01370	COG1132	(ABC) transporter
CB0101_RS01380	COG0149	triose-phosphate isomerase activity
CB0101_RS01385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CB0101_RS01390	COG5001	Diguanylate cyclase
CB0101_RS01395	COG1215	transferase activity, transferring glycosyl groups
CB0101_RS01410	COG1429	ligase activity, forming nitrogen-metal bonds
CB0101_RS01415	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CB0101_RS01425	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CB0101_RS01440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CB0101_RS01500	COG4106	trans-aconitate 2-methyltransferase activity
CB0101_RS01505	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CB0101_RS01520	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CB0101_RS01525	COG1122	ATPase activity
CB0101_RS01535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CB0101_RS01545	COG1836	PFAM Integral membrane protein DUF92
CB0101_RS01560	COG3639	organic phosphonate transmembrane transporter activity
CB0101_RS01565	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CB0101_RS01575	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CB0101_RS01580	COG0436	Aminotransferase
CB0101_RS01590	COG1573	uracil-dna glycosylase
CB0101_RS01595	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CB0101_RS01600	COG0793	Belongs to the peptidase S41A family
CB0101_RS01610	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CB0101_RS01630	COG0861	Integral membrane protein TerC family
CB0101_RS01645	COG0513	Belongs to the DEAD box helicase family
CB0101_RS01655	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CB0101_RS01665	COG0312	modulator of DNA gyrase
CB0101_RS01670	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CB0101_RS01685	COG0163	prenyltransferase activity
CB0101_RS01690	COG0557	exoribonuclease II activity
CB0101_RS01700	COG2119	membrane
CB0101_RS01715	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CB0101_RS01715	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CB0101_RS01720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CB0101_RS01730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CB0101_RS01730	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CB0101_RS01735	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CB0101_RS01740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CB0101_RS01750	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CB0101_RS01755	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CB0101_RS01765	COG0191	fructose-bisphosphate aldolase activity
CB0101_RS01770	COG0673	inositol 2-dehydrogenase activity
CB0101_RS01780	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CB0101_RS01785	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CB0101_RS01795	COG3954	Phosphoribulokinase
CB0101_RS01800	COG0473	3-isopropylmalate dehydrogenase activity
CB0101_RS01805	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CB0101_RS01810	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CB0101_RS01825	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CB0101_RS01850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CB0101_RS01860	COG0114	fumarate hydratase activity
CB0101_RS01865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CB0101_RS01870	COG2197	response regulator
CB0101_RS01880	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CB0101_RS01895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CB0101_RS01915	COG0625	glutathione transferase activity
CB0101_RS01990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CB0101_RS02015	COG2124	cytochrome p450
CB0101_RS02050	COG1970	mechanosensitive ion channel activity
CB0101_RS02085	COG3631	Ketosteroid isomerase-related protein
CB0101_RS02090	COG0724	RNA recognition motif
CB0101_RS02100	COG0058	SHG alpha-glucan phosphorylase activity
CB0101_RS02130	COG0281	malic enzyme
CB0101_RS02170	COG1201	RNA secondary structure unwinding
CB0101_RS02175	COG1793	dna ligase
CB0101_RS02185	COG3588	fructose-bisphosphate aldolase
CB0101_RS02220	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CB0101_RS02225	COG0514	ATP-dependent DNA helicase (RecQ)
CB0101_RS02230	COG1175	transmembrane transport
CB0101_RS02235	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CB0101_RS02265	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CB0101_RS02280	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CB0101_RS02295	COG0740	serine-type endopeptidase activity
CB0101_RS02320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CB0101_RS02330	COG0577	efflux transmembrane transporter activity
CB0101_RS02330	COG1136	(ABC) transporter
CB0101_RS02335	COG0469	pyruvate kinase activity
CB0101_RS02360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CB0101_RS02365	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CB0101_RS02435	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CB0101_RS02435	COG0284	orotidine-5'-phosphate decarboxylase activity
CB0101_RS02515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CB0101_RS02520	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CB0101_RS02530	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CB0101_RS02535	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CB0101_RS02570	COG1653	transport
CB0101_RS02575	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CB0101_RS02600	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CB0101_RS02605	COG0483	inositol monophosphate 1-phosphatase activity
CB0101_RS02620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CB0101_RS02625	COG0581	inorganic phosphate transmembrane transporter activity
CB0101_RS02630	COG0573	inorganic phosphate transmembrane transporter activity
CB0101_RS02640	COG0484	heat shock protein binding
CB0101_RS02650	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CB0101_RS02655	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CB0101_RS02660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CB0101_RS02665	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CB0101_RS02665	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CB0101_RS02670	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CB0101_RS02675	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CB0101_RS02700	COG0166	Belongs to the GPI family
CB0101_RS02705	COG0495	leucyl-tRNA aminoacylation
CB0101_RS02715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CB0101_RS02720	COG1104	cysteine desulfurase activity
CB0101_RS02735	COG2027	D-alanyl-D-alanine carboxypeptidase
CB0101_RS02745	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CB0101_RS02750	COG0426	domain, Protein
CB0101_RS02750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CB0101_RS02755	COG0322	excinuclease ABC activity
CB0101_RS02765	COG3046	protein related to deoxyribodipyrimidine photolyase
CB0101_RS02775	COG1981	membrane
CB0101_RS02780	COG0587	DNA-directed DNA polymerase activity
CB0101_RS02795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CB0101_RS02800	COG1410	methionine synthase
CB0101_RS02800	COG0646	methionine synthase
CB0101_RS02820	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CB0101_RS02830	COG2385	sporulation resulting in formation of a cellular spore
CB0101_RS02870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CB0101_RS02875	COG0072	phenylalanine-tRNA ligase activity
CB0101_RS02880	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CB0101_RS02885	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CB0101_RS02890	COG0557	exoribonuclease II activity
CB0101_RS02915	COG1028	Short-chain dehydrogenase reductase Sdr
CB0101_RS02925	COG3263	regulation of cellular component size
CB0101_RS02950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CB0101_RS02985	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CB0101_RS03005	COG1115	amino acid carrier protein
CB0101_RS03055	COG1064	alcohol dehydrogenase
CB0101_RS03085	COG0450	alkyl hydroperoxide reductase
CB0101_RS03090	COG1619	proteins homologs of microcin C7 resistance protein MccF
CB0101_RS03095	COG0047	phosphoribosylformylglycinamidine synthase activity
CB0101_RS03100	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CB0101_RS03125	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CB0101_RS03135	COG0129	dihydroxy-acid dehydratase activity
CB0101_RS03155	COG0363	glucosamine-6-phosphate deaminase activity
CB0101_RS03160	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CB0101_RS03165	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CB0101_RS03170	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CB0101_RS03175	COG1494	fructose-1,6-bisphosphatase
CB0101_RS03180	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CB0101_RS03185	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CB0101_RS03195	COG1137	ATPase activity
CB0101_RS03210	COG1217	gtp-binding protein TYPA
CB0101_RS03215	COG0826	peptidase U32
CB0101_RS03225	COG0644	oxidoreductase
CB0101_RS03235	COG0751	glycine-tRNA ligase activity
CB0101_RS03240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CB0101_RS03245	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CB0101_RS03250	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CB0101_RS03260	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CB0101_RS03265	COG0052	Belongs to the universal ribosomal protein uS2 family
CB0101_RS03270	COG1216	Glycosyl transferase, family 2
CB0101_RS03280	COG1136	(ABC) transporter
CB0101_RS03290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CB0101_RS03300	COG0612	Peptidase, M16
CB0101_RS03320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CB0101_RS03325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CB0101_RS03330	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CB0101_RS03350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CB0101_RS03360	COG0174	glutamine synthetase
CB0101_RS03390	COG0515	serine threonine protein kinase
CB0101_RS03395	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CB0101_RS03400	COG3310	Protein conserved in bacteria
CB0101_RS03420	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CB0101_RS03425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CB0101_RS03430	COG0022	dehydrogenase e1 component
CB0101_RS03440	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CB0101_RS03445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CB0101_RS03480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CB0101_RS03495	COG0358	DNA primase activity
CB0101_RS03510	COG0632	four-way junction helicase activity
CB0101_RS03515	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CB0101_RS03525	COG0587	DNA-directed DNA polymerase activity
CB0101_RS03530	COG0154	amidase activity
CB0101_RS03540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CB0101_RS03545	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CB0101_RS03555	COG0505	Belongs to the CarA family
CB0101_RS03560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CB0101_RS03570	COG1132	(ABC) transporter
CB0101_RS03580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CB0101_RS03610	COG2176	DNA-directed DNA polymerase activity
CB0101_RS03615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CB0101_RS03625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CB0101_RS03630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CB0101_RS03635	COG0142	geranyltranstransferase activity
CB0101_RS03640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CB0101_RS03645	COG0860	N-Acetylmuramoyl-L-alanine amidase
CB0101_RS03655	COG2045	Belongs to the ComB family
CB0101_RS03660	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CB0101_RS03670	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CB0101_RS03675	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CB0101_RS03675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CB0101_RS03680	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CB0101_RS03685	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CB0101_RS03695	COG0297	glycogen (starch) synthase activity
CB0101_RS03700	COG1376	ErfK ybiS ycfS ynhG family protein
CB0101_RS03705	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CB0101_RS03710	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CB0101_RS03715	COG0681	Belongs to the peptidase S26 family
CB0101_RS03730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CB0101_RS03735	COG1121	(ABC) transporter
CB0101_RS03740	COG0803	Belongs to the bacterial solute-binding protein 9 family
CB0101_RS03800	COG0180	Tryptophanyl-tRNA synthetase
CB0101_RS03815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CB0101_RS03820	COG0837	glucose binding
CB0101_RS03825	COG0083	homoserine kinase activity
CB0101_RS03830	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CB0101_RS03835	COG0339	signal peptide processing
CB0101_RS03870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CB0101_RS03910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CB0101_RS03915	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CB0101_RS03925	COG2010	Cytochrome c
CB0101_RS03955	COG0542	response to heat
CB0101_RS03980	COG0432	Pfam Uncharacterised protein family UPF0047
CB0101_RS04030	COG0181	hydroxymethylbilane synthase activity
CB0101_RS04050	COG1216	Glycosyl transferase, family 2
CB0101_RS04055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CB0101_RS04060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CB0101_RS04070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CB0101_RS04085	COG0629	single-stranded DNA binding
CB0101_RS04090	COG2099	Precorrin-6x reductase
CB0101_RS04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CB0101_RS04105	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CB0101_RS04115	COG0442	prolyl-tRNA aminoacylation
CB0101_RS04125	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CB0101_RS04150	COG0681	Belongs to the peptidase S26 family
CB0101_RS04155	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CB0101_RS04175	COG0768	penicillin binding
CB0101_RS04180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CB0101_RS04195	COG0233	cytoplasmic translational termination
CB0101_RS04200	COG0528	UMP kinase activity
CB0101_RS04220	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CB0101_RS04255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CB0101_RS04255	COG0574	Belongs to the PEP-utilizing enzyme family
CB0101_RS04270	COG1034	ATP synthesis coupled electron transport
CB0101_RS04275	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CB0101_RS04280	COG3259	Nickel-dependent hydrogenase
CB0101_RS04290	COG0375	protein maturation
CB0101_RS04295	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CB0101_RS04300	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CB0101_RS04305	COG0298	carbon dioxide binding
CB0101_RS04310	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CB0101_RS04310	COG0674	pyruvate-flavodoxin oxidoreductase activity
CB0101_RS04310	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CB0101_RS04310	COG1013	pyruvate-flavodoxin oxidoreductase activity
CB0101_RS04325	COG0309	Hydrogenase expression formation protein (HypE)
CB0101_RS04395	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CB0101_RS04410	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CB0101_RS04445	COG0071	Belongs to the small heat shock protein (HSP20) family
CB0101_RS04450	COG2199	diguanylate cyclase activity
CB0101_RS04475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CB0101_RS04480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CB0101_RS04485	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CB0101_RS04510	COG2059	Chromate
CB0101_RS04525	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CB0101_RS04535	COG0415	Belongs to the DNA photolyase family
CB0101_RS04540	COG1496	oxidoreductase activity
CB0101_RS04550	COG0539	negative regulation of cytoplasmic translation
CB0101_RS04560	COG3396	Phenylacetate-CoA oxygenase
CB0101_RS04565	COG5322	oxidoreductase activity
CB0101_RS04570	COG0825	malonyl-CoA metabolic process
CB0101_RS04580	COG0302	gtp cyclohydrolase
CB0101_RS04590	COG0135	phosphoribosylanthranilate isomerase activity
CB0101_RS04595	COG1994	Peptidase M50
CB0101_RS04595	COG0517	IMP dehydrogenase activity
CB0101_RS04600	COG0095	Lipoate-protein ligase
CB0101_RS04635	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CB0101_RS04640	COG1228	amidohydrolase
CB0101_RS04645	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CB0101_RS04650	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CB0101_RS04655	COG0569	domain protein
CB0101_RS04660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CB0101_RS04665	COG1253	flavin adenine dinucleotide binding
CB0101_RS04675	COG0471	metal ion transport
CB0101_RS04675	COG3273	potassium ion transport
CB0101_RS04680	COG1959	2 iron, 2 sulfur cluster binding
CB0101_RS04685	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CB0101_RS04695	COG0004	ammonium transporteR
CB0101_RS04725	COG0475	glutathione-regulated potassium exporter activity
CB0101_RS04730	COG1006	Multisubunit Na H antiporter MnhC subunit
CB0101_RS04735	COG0651	ATP synthesis coupled electron transport
CB0101_RS04765	COG0659	secondary active sulfate transmembrane transporter activity
CB0101_RS04775	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CB0101_RS04780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CB0101_RS04790	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CB0101_RS04800	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CB0101_RS04810	COG0531	amino acid
CB0101_RS04830	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CB0101_RS04835	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CB0101_RS04850	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CB0101_RS04855	COG1850	ribulose-bisphosphate carboxylase activity
CB0101_RS04860	COG4451	ribulose bisphosphate carboxylase, small
CB0101_RS04885	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CB0101_RS04895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CB0101_RS04900	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CB0101_RS04915	COG0464	growth
CB0101_RS04925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CB0101_RS04935	COG3781	membrane
CB0101_RS04945	COG2200	EAL domain
CB0101_RS04945	COG2199	diguanylate cyclase activity
CB0101_RS04950	COG0456	acetyltransferase
CB0101_RS04960	COG1132	(ABC) transporter
CB0101_RS04965	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CB0101_RS04970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CB0101_RS04975	COG3842	ATPase activity
CB0101_RS04980	COG0251	oxidation-reduction process
CB0101_RS04990	COG4942	peptidase
CB0101_RS05090	COG0545	Peptidyl-prolyl cis-trans isomerase
CB0101_RS05115	COG1525	nuclease
CB0101_RS05170	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CB0101_RS05170	COG0662	Cupin 2, conserved barrel domain protein
CB0101_RS05195	COG0463	Glycosyl transferase, family 2
CB0101_RS05205	COG1216	Glycosyl transferase, family 2
CB0101_RS05205	COG0438	transferase activity, transferring glycosyl groups
CB0101_RS05210	COG0438	transferase activity, transferring glycosyl groups
CB0101_RS05220	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CB0101_RS05250	COG4423	Transcription factor
CB0101_RS05265	COG0297	glycogen (starch) synthase activity
CB0101_RS05290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CB0101_RS05305	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CB0101_RS05335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CB0101_RS05345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CB0101_RS05360	COG2801	Transposase and inactivated derivatives
CB0101_RS05380	COG3039	Transposase
CB0101_RS05390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CB0101_RS05405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CB0101_RS05410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CB0101_RS05415	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CB0101_RS05475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CB0101_RS05480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CB0101_RS05480	COG0140	phosphoribosyl-ATP diphosphatase activity
CB0101_RS05495	COG0701	Predicted permease
CB0101_RS05520	COG1121	(ABC) transporter
CB0101_RS05525	COG3659	wide pore channel activity
CB0101_RS05535	COG1528	Iron-storage protein
CB0101_RS05540	COG0783	Belongs to the Dps family
CB0101_RS05550	COG0523	cobalamin synthesis protein
CB0101_RS05560	COG0735	belongs to the Fur family
CB0101_RS05570	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CB0101_RS05595	COG0708	Exodeoxyribonuclease III
CB0101_RS05600	COG0277	FAD linked oxidase domain protein
CB0101_RS05605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CB0101_RS05615	COG0559	Belongs to the binding-protein-dependent transport system permease family
CB0101_RS05645	COG0405	Gamma-glutamyltransferase
CB0101_RS05660	COG1666	GTP binding
CB0101_RS05685	COG0857	belongs to the CobB CobQ family
CB0101_RS05695	COG0300	oxidoreductase activity
CB0101_RS05695	COG3000	fatty acid hydroxylase
CB0101_RS05700	COG0024	Methionine aminopeptidase
CB0101_RS05710	COG0335	large ribosomal subunit rRNA binding
CB0101_RS05730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CB0101_RS05760	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CB0101_RS05760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CB0101_RS05765	COG0215	cysteine-tRNA ligase activity
CB0101_RS05775	COG0733	neurotransmitter:sodium symporter activity
CB0101_RS05790	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CB0101_RS05830	COG0492	ferredoxin-NADP+ reductase activity
CB0101_RS05840	COG1187	pseudouridine synthase activity
CB0101_RS05850	COG0702	epimerase
CB0101_RS05870	COG0440	acetolactate synthase activity
CB0101_RS05875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CB0101_RS05945	COG2361	Protein of unknown function DUF86
CB0101_RS05955	COG0424	maF-like protein
CB0101_RS05965	COG1492	cobalamin metabolic process
CB0101_RS05985	COG0482	sulfurtransferase activity
CB0101_RS05990	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CB0101_RS05990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CB0101_RS05995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CB0101_RS06075	COG0123	including yeast histone deacetylase and acetoin utilization protein
CB0101_RS06080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CB0101_RS06090	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CB0101_RS06095	COG0228	four-way junction DNA binding
CB0101_RS06100	COG1702	phosphate starvation-inducible protein PhoH
CB0101_RS06105	COG0670	Belongs to the BI1 family
CB0101_RS06115	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CB0101_RS06125	COG0336	Belongs to the RNA methyltransferase TrmD family
CB0101_RS06130	COG0330	HflC and HflK could
CB0101_RS06140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CB0101_RS06150	COG1691	(AIR) carboxylase
CB0101_RS06170	COG0352	thiamine-phosphate diphosphorylase activity
CB0101_RS06175	COG0196	riboflavin kinase activity
CB0101_RS06185	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CB0101_RS06190	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CB0101_RS06195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CB0101_RS06200	COG0745	RESPONSE REGULATOR receiver
CB0101_RS06225	COG0641	radical SAM
CB0101_RS06230	COG0628	permease
CB0101_RS06260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CB0101_RS06260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CB0101_RS06270	COG2135	peptidase activity
CB0101_RS06275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CB0101_RS06280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CB0101_RS06290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CB0101_RS06365	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CB0101_RS06380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CB0101_RS06390	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CB0101_RS06395	COG0508	dehydrogenase complex catalyzes the overall conversion of
CB0101_RS06405	COG1022	Amp-dependent synthetase and ligase
CB0101_RS06410	COG0321	lipoyl(octanoyl) transferase activity
CB0101_RS06415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CB0101_RS06420	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CB0101_RS06435	COG0438	transferase activity, transferring glycosyl groups
CB0101_RS06440	COG0284	orotidine-5'-phosphate decarboxylase activity
CB0101_RS06450	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CB0101_RS06490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CB0101_RS06500	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CB0101_RS06505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CB0101_RS06510	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CB0101_RS06520	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CB0101_RS06530	COG0151	Belongs to the GarS family
CB0101_RS06535	COG5002	protein histidine kinase activity
CB0101_RS06540	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CB0101_RS06545	COG4251	negative regulation of phosphorylation
CB0101_RS06555	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CB0101_RS06560	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CB0101_RS06565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CB0101_RS06570	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CB0101_RS06575	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CB0101_RS06580	COG0217	transcriptional regulatory protein
CB0101_RS06585	COG0363	glucosamine-6-phosphate deaminase activity
CB0101_RS06590	COG2247	cell wall binding repeat
CB0101_RS06590	COG2385	sporulation resulting in formation of a cellular spore
CB0101_RS06595	COG1234	tRNA 3'-trailer cleavage
CB0101_RS06600	COG2010	Cytochrome c
CB0101_RS06615	COG2264	protein methyltransferase activity
CB0101_RS06620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CB0101_RS06640	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CB0101_RS06680	COG0443	Heat shock 70 kDa protein
CB0101_RS06695	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CB0101_RS06710	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CB0101_RS06715	COG0004	ammonium transporteR
CB0101_RS06720	COG0459	protein refolding
CB0101_RS06725	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CB0101_RS06730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CB0101_RS06735	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CB0101_RS06745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CB0101_RS06760	COG0515	serine threonine protein kinase
CB0101_RS06760	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CB0101_RS06790	COG0006	proline dipeptidase activity
CB0101_RS06795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CB0101_RS06800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CB0101_RS06805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CB0101_RS06805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CB0101_RS06810	COG0686	Belongs to the AlaDH PNT family
CB0101_RS06820	COG3012	SEC-C Motif Domain Protein
CB0101_RS06825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CB0101_RS06835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CB0101_RS06845	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CB0101_RS06850	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CB0101_RS06860	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CB0101_RS06865	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CB0101_RS06870	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CB0101_RS06885	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CB0101_RS06890	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CB0101_RS06910	COG0772	Belongs to the SEDS family
CB0101_RS06925	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CB0101_RS06930	COG0347	Belongs to the P(II) protein family
CB0101_RS06935	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CB0101_RS06945	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CB0101_RS06950	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CB0101_RS06955	COG4581	dead DEAH box helicase
CB0101_RS06975	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CB0101_RS06990	COG0484	heat shock protein binding
CB0101_RS06995	COG0357	Ribosomal RNA small subunit methyltransferase G
CB0101_RS07025	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CB0101_RS07030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CB0101_RS07035	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CB0101_RS07040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CB0101_RS07045	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CB0101_RS07050	COG0085	RNA polymerase activity
CB0101_RS07055	COG0084	hydrolase, TatD family'
CB0101_RS07060	COG0268	Binds directly to 16S ribosomal RNA
CB0101_RS07065	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CB0101_RS07070	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CB0101_RS07075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CB0101_RS07080	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CB0101_RS07090	COG0779	Required for maturation of 30S ribosomal subunits
CB0101_RS07095	COG0195	Participates in both transcription termination and antitermination
CB0101_RS07105	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CB0101_RS07160	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CB0101_RS07165	COG3039	Transposase
CB0101_RS07260	COG2988	succinylglutamate desuccinylase activity
CB0101_RS07275	COG3039	Transposase
CB0101_RS07300	COG0167	dihydroorotate dehydrogenase activity
CB0101_RS07305	COG0328	RNA-DNA hybrid ribonuclease activity
CB0101_RS07315	COG0222	ribosome binding
CB0101_RS07320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CB0101_RS07325	COG0081	regulation of translation
CB0101_RS07330	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CB0101_RS07335	COG0250	Participates in transcription elongation, termination and antitermination
CB0101_RS07340	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CB0101_RS07345	COG0542	response to heat
CB0101_RS07350	COG0346	lactoylglutathione lyase activity
CB0101_RS07355	COG0148	phosphopyruvate hydratase activity
CB0101_RS07360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CB0101_RS07380	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CB0101_RS07385	COG0237	dephospho-CoA kinase activity
CB0101_RS07405	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CB0101_RS07410	COG2022	thiamine diphosphate biosynthetic process
CB0101_RS07410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CB0101_RS07420	COG0105	UTP biosynthetic process
CB0101_RS07440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CB0101_RS07440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CB0101_RS07455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CB0101_RS07465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CB0101_RS07485	COG0426	domain, Protein
CB0101_RS07485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CB0101_RS07495	COG1475	DNA binding
CB0101_RS07505	COG3039	Transposase
CB0101_RS07510	COG0426	domain, Protein
CB0101_RS07510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CB0101_RS07525	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CB0101_RS07525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CB0101_RS07530	COG0509	glycine decarboxylation via glycine cleavage system
CB0101_RS07535	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CB0101_RS07555	COG0359	binds to the 23S rRNA
CB0101_RS07560	COG1372	Participates in initiation and elongation during chromosome replication
CB0101_RS07560	COG0305	Participates in initiation and elongation during chromosome replication
CB0101_RS07560	COG0305	Participates in initiation and elongation during chromosome replication
CB0101_RS07560	COG1372	Participates in initiation and elongation during chromosome replication
CB0101_RS07565	COG0445	tRNA wobble uridine modification
CB0101_RS07600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CB0101_RS07610	COG0398	Pfam SNARE associated Golgi protein
CB0101_RS07620	COG0525	valine-tRNA ligase activity
CB0101_RS07630	COG3264	Mechanosensitive ion channel
CB0101_RS07630	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CB0101_RS07650	COG2226	methyltransferase
CB0101_RS07660	COG3118	belongs to the thioredoxin family
CB0101_RS07670	COG3039	Transposase
CB0101_RS07690	COG3328	transposase activity
CB0101_RS07750	COG3956	TIGRFAM MazG family protein
CB0101_RS07765	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CB0101_RS07770	COG0010	Belongs to the arginase family
CB0101_RS07785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CB0101_RS07790	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CB0101_RS07795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CB0101_RS07800	COG0504	CTP synthase activity
CB0101_RS07805	COG0602	queuosine metabolic process
CB0101_RS07810	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CB0101_RS07815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CB0101_RS07830	COG0531	amino acid
CB0101_RS07840	COG0411	ABC transporter
CB0101_RS07860	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CB0101_RS07870	COG0830	nickel cation binding
CB0101_RS07875	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CB0101_RS07880	COG0829	nickel cation binding
CB0101_RS07885	COG0831	urea catabolic process
CB0101_RS07890	COG0832	Belongs to the urease beta subunit family
CB0101_RS07895	COG0804	urea catabolic process
CB0101_RS07905	COG2308	Evidence 4 Homologs of previously reported genes of
CB0101_RS07940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CB0101_RS07955	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CB0101_RS07965	COG2116	formate transmembrane transporter activity
CB0101_RS07975	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CB0101_RS07980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CB0101_RS07995	COG0243	molybdopterin cofactor binding
CB0101_RS08000	COG2223	nitrite transmembrane transporter activity
CB0101_RS08010	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CB0101_RS08015	COG0730	response to heat
CB0101_RS08025	COG0521	Mo-molybdopterin cofactor biosynthetic process
CB0101_RS08035	COG0314	molybdopterin synthase activity
CB0101_RS08040	COG0303	'Molybdopterin
CB0101_RS08045	COG0315	cyclic pyranopterin monophosphate synthase activity
CB0101_RS08055	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CB0101_RS08060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CB0101_RS08065	COG0170	dolichyl monophosphate biosynthetic process
CB0101_RS08075	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CB0101_RS08080	COG1049	propionate catabolic process, 2-methylcitrate cycle
CB0101_RS08085	COG0038	chloride channel
CB0101_RS08105	COG0788	formyltetrahydrofolate deformylase activity
CB0101_RS08115	COG2022	thiamine diphosphate biosynthetic process
CB0101_RS08115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CB0101_RS08125	COG0443	Heat shock 70 kDa protein
CB0101_RS08130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CB0101_RS08140	COG0360	Binds together with S18 to 16S ribosomal RNA
CB0101_RS08150	COG0137	argininosuccinate synthase activity
CB0101_RS08165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CB0101_RS08180	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CB0101_RS08185	COG1316	TRANSCRIPTIONal
CB0101_RS08190	COG0438	transferase activity, transferring glycosyl groups
CB0101_RS08195	COG0556	nucleotide-excision repair
CB0101_RS08210	COG0037	tRNA processing
CB0101_RS08220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CB0101_RS08225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CB0101_RS08230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CB0101_RS08235	COG0544	peptidyl-prolyl cis-trans isomerase activity
CB0101_RS08240	COG0740	serine-type endopeptidase activity
CB0101_RS08245	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CB0101_RS08255	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CB0101_RS08260	COG1215	transferase activity, transferring glycosyl groups
CB0101_RS08265	COG2385	sporulation resulting in formation of a cellular spore
CB0101_RS08270	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CB0101_RS08275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CB0101_RS08290	COG2022	thiamine diphosphate biosynthetic process
CB0101_RS08300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CB0101_RS08305	COG0438	transferase activity, transferring glycosyl groups
CB0101_RS08305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CB0101_RS08310	COG0768	penicillin binding
CB0101_RS08325	COG0519	Catalyzes the synthesis of GMP from XMP
CB0101_RS08325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CB0101_RS08330	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CB0101_RS08400	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CB0101_RS08405	COG0511	ligase activity, forming carbon-carbon bonds
CB0101_RS08410	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CB0101_RS08415	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CB0101_RS08420	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CB0101_RS08425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CB0101_RS08430	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CB0101_RS08435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CB0101_RS08440	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CB0101_RS08445	COG1162	GTPase activity
CB0101_RS08455	COG0484	heat shock protein binding
CB0101_RS08460	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CB0101_RS08465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CB0101_RS08475	COG1459	type II secretion system
CB0101_RS08490	COG2081	HI0933 family
CB0101_RS08495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CB0101_RS08500	COG0724	RNA recognition motif
CB0101_RS08505	COG0165	Argininosuccinate lyase
CB0101_RS08510	COG2208	phosphoserine phosphatase activity
CB0101_RS08515	COG0552	protein localization to endoplasmic reticulum
CB0101_RS08520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CB0101_RS08535	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CB0101_RS08545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CB0101_RS08550	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CB0101_RS08580	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CB0101_RS08600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CB0101_RS08605	COG0497	DNA recombination
CB0101_RS08610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CB0101_RS08620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CB0101_RS08625	COG0592	DNA-directed DNA polymerase activity
CB0101_RS08640	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CB0101_RS08645	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CB0101_RS08670	COG2082	Precorrin-8x methylmutase
CB0101_RS08685	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CB0101_RS08695	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CB0101_RS08730	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CB0101_RS08770	COG0277	FAD linked oxidase domain protein
CB0101_RS08795	COG1088	dTDP-glucose 4,6-dehydratase activity
CB0101_RS08810	COG0438	transferase activity, transferring glycosyl groups
CB0101_RS08810	COG1216	Glycosyl transferase, family 2
CB0101_RS08895	COG2274	protein secretion by the type I secretion system
CB0101_RS08910	COG0297	glycogen (starch) synthase activity
CB0101_RS08935	COG3039	Transposase
CB0101_RS08945	COG0456	acetyltransferase
CB0101_RS08955	COG4423	Transcription factor
CB0101_RS08960	COG0653	protein targeting
CB0101_RS08970	COG2192	nodulation
CB0101_RS08990	COG1045	serine acetyltransferase
CB0101_RS08995	COG4456	Virulence-associated protein
CB0101_RS09005	COG1725	Transcriptional regulator
CB0101_RS09010	COG0412	Dienelactone hydrolase
CB0101_RS09025	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CB0101_RS09030	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CB0101_RS09035	COG0187	DNA topoisomerase II activity
CB0101_RS09035	COG1372	Participates in initiation and elongation during chromosome replication
CB0101_RS09045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CB0101_RS09050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CB0101_RS09055	COG0386	Belongs to the glutathione peroxidase family
CB0101_RS09065	COG2239	Acts as a magnesium transporter
CB0101_RS09070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CB0101_RS09080	COG1194	a g-specific adenine glycosylase
CB0101_RS09090	COG0802	atpase or kinase
CB0101_RS09095	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CB0101_RS09100	COG0586	Pfam SNARE associated Golgi protein
CB0101_RS09105	COG0629	single-stranded DNA binding
CB0101_RS09115	COG1792	Involved in formation and maintenance of cell shape
CB0101_RS09130	COG0745	RESPONSE REGULATOR receiver
CB0101_RS09135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CB0101_RS09160	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CB0101_RS09180	COG0515	serine threonine protein kinase
CB0101_RS09200	COG1473	amidohydrolase
CB0101_RS09215	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CB0101_RS09225	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CB0101_RS09230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CB0101_RS09235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CB0101_RS09240	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CB0101_RS09255	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CB0101_RS09265	COG0571	ribonuclease III activity
CB0101_RS09295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CB0101_RS09300	COG0058	SHG alpha-glucan phosphorylase activity
CB0101_RS09305	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CB0101_RS09310	COG0475	glutathione-regulated potassium exporter activity
CB0101_RS09335	COG0277	FAD linked oxidase domain protein
CB0101_RS09365	COG0531	amino acid
CB0101_RS09370	COG0247	lactate metabolic process
CB0101_RS09375	COG0538	isocitrate dehydrogenase activity
CB0101_RS09385	COG5398	heme oxygenase
CB0101_RS09395	COG1132	(ABC) transporter
CB0101_RS09400	COG1132	(ABC) transporter
CB0101_RS09405	COG0438	transferase activity, transferring glycosyl groups
CB0101_RS09435	COG0617	tRNA 3'-terminal CCA addition
CB0101_RS09435	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CB0101_RS09435	COG0517	IMP dehydrogenase activity
CB0101_RS09450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CB0101_RS09455	COG0124	histidyl-tRNA synthetase
CB0101_RS09460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CB0101_RS09495	COG4447	cellulose binding
CB0101_RS09500	COG1773	rubredoxin
CB0101_RS09505	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CB0101_RS09520	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CB0101_RS09525	COG3842	ATPase activity
CB0101_RS09535	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CB0101_RS09535	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CB0101_RS09545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CB0101_RS09560	COG0494	nUDIX hydrolase
CB0101_RS09565	COG0415	Belongs to the DNA photolyase family
CB0101_RS09590	COG0415	Belongs to the DNA photolyase family
CB0101_RS09595	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CB0101_RS09600	COG0131	Imidazoleglycerol-phosphate dehydratase
CB0101_RS09605	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CB0101_RS09620	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CB0101_RS09625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CB0101_RS09635	COG0354	folic acid binding
CB0101_RS09640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CB0101_RS09660	COG1253	flavin adenine dinucleotide binding
CB0101_RS09665	COG0673	inositol 2-dehydrogenase activity
CB0101_RS09685	COG0343	queuine tRNA-ribosyltransferase activity
CB0101_RS09690	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CB0101_RS09695	COG2205	protein histidine kinase activity
CB0101_RS09710	COG0138	bifunctional purine biosynthesis protein purh
CB0101_RS09725	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CB0101_RS09730	COG1489	DNA binding
CB0101_RS09735	COG0728	peptidoglycan biosynthetic process
CB0101_RS09760	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CB0101_RS09765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CB0101_RS09770	COG1058	Belongs to the CinA family
CB0101_RS09770	COG1546	Belongs to the CinA family
CB0101_RS09775	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CB0101_RS09780	COG0066	3-isopropylmalate dehydratase activity
CB0101_RS09815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CB0101_RS09820	COG0193	aminoacyl-tRNA hydrolase activity
CB0101_RS09835	COG4372	Transposase
CB0101_RS09840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CB0101_RS09845	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CB0101_RS09855	COG0717	Belongs to the dCTP deaminase family
CB0101_RS09865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CB0101_RS09880	COG0741	lytic transglycosylase activity
CB0101_RS09890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CB0101_RS09905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CB0101_RS09930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CB0101_RS09950	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CB0101_RS09955	COG1402	creatininase
CB0101_RS09965	COG2094	Belongs to the DNA glycosylase MPG family
CB0101_RS09975	COG2801	Transposase and inactivated derivatives
CB0101_RS10035	COG2094	Belongs to the DNA glycosylase MPG family
CB0101_RS10040	COG0540	Belongs to the ATCase OTCase family
CB0101_RS10065	COG3536	Protein conserved in bacteria
CB0101_RS10070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CB0101_RS10085	COG0529	Catalyzes the synthesis of activated sulfate
CB0101_RS10085	COG2046	Belongs to the sulfate adenylyltransferase family
CB0101_RS10090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CB0101_RS10105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CB0101_RS10110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CB0101_RS10120	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CB0101_RS10125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CB0101_RS10130	COG2205	protein histidine kinase activity
CB0101_RS10145	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CB0101_RS10150	COG0436	Aminotransferase
CB0101_RS10160	COG1530	ribonuclease E activity
CB0101_RS10165	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CB0101_RS10175	COG1605	Chorismate mutase
CB0101_RS10175	COG0077	Prephenate dehydratase
CB0101_RS10180	COG2226	methyltransferase
CB0101_RS10190	COG0051	transcription antitermination factor activity, RNA binding
CB0101_RS10195	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CB0101_RS10200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CB0101_RS10205	COG0049	tRNA binding
CB0101_RS10210	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CB0101_RS10225	COG0070	glutamate synthase
CB0101_RS10225	COG0067	glutamate synthase
CB0101_RS10225	COG0069	glutamate synthase activity
CB0101_RS10235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CB0101_RS10255	COG2885	chlorophyll binding
CB0101_RS10260	COG2885	chlorophyll binding
CB0101_RS10265	COG0009	L-threonylcarbamoyladenylate synthase
CB0101_RS10270	COG2890	protein-(glutamine-N5) methyltransferase activity
CB0101_RS10275	COG0758	DNA mediated transformation
CB0101_RS10285	COG0589	response to stress
CB0101_RS10310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CB0101_RS10315	COG0539	negative regulation of cytoplasmic translation
CB0101_RS10320	COG0546	phosphoglycolate phosphatase activity
CB0101_RS10325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CB0101_RS10330	COG1070	Carbohydrate kinase
CB0101_RS10360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CB0101_RS10410	COG1413	lyase activity
CB0101_RS10415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CB0101_RS10420	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CB0101_RS10420	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CB0101_RS10425	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CB0101_RS10430	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CB0101_RS10480	COG2755	lipolytic protein G-D-S-L family
CB0101_RS10480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CB0101_RS10500	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CB0101_RS10520	COG0408	coproporphyrinogen oxidase activity
CB0101_RS10525	COG0489	protein tyrosine kinase activity
CB0101_RS10530	COG0772	Belongs to the SEDS family
CB0101_RS10545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CB0101_RS10550	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CB0101_RS10555	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CB0101_RS10570	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CB0101_RS10575	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CB0101_RS10590	COG1606	tRNA processing
CB0101_RS10595	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CB0101_RS10615	COG3001	Fructosamine kinase
CB0101_RS10660	COG3854	ATPases associated with a variety of cellular activities
CB0101_RS10675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CB0101_RS10680	COG0088	Forms part of the polypeptide exit tunnel
CB0101_RS10685	COG0089	rRNA binding
CB0101_RS10690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CB0101_RS10695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CB0101_RS10700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CB0101_RS10705	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CB0101_RS10710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CB0101_RS10715	COG0255	Belongs to the universal ribosomal protein uL29 family
CB0101_RS10720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CB0101_RS10725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CB0101_RS10730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CB0101_RS10735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CB0101_RS10740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CB0101_RS10745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CB0101_RS10750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CB0101_RS10755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CB0101_RS10760	COG0200	Binds to the 23S rRNA
CB0101_RS10765	COG0201	protein transport
CB0101_RS10770	COG0563	adenylate kinase activity
CB0101_RS10775	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CB0101_RS10780	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CB0101_RS10785	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CB0101_RS10790	COG0202	RNA polymerase activity
CB0101_RS10795	COG0203	ribosomal protein L17
CB0101_RS10800	COG0101	tRNA pseudouridine synthase activity
CB0101_RS10805	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CB0101_RS10810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CB0101_RS10815	COG0254	rRNA binding
CB0101_RS10820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CB0101_RS10830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CB0101_RS10850	COG1132	(ABC) transporter
CB0101_RS10855	COG0745	RESPONSE REGULATOR receiver
CB0101_RS10875	COG5505	Protein of unknown function (DUF819)
CB0101_RS10880	COG0463	Glycosyl transferase, family 2
CB0101_RS10915	COG0463	Glycosyl transferase, family 2
CB0101_RS10935	COG3659	wide pore channel activity
CB0101_RS10940	COG3659	wide pore channel activity
CB0101_RS10945	COG0484	heat shock protein binding
CB0101_RS10960	COG1090	epimerase
CB0101_RS10990	COG0316	Belongs to the HesB IscA family
CB0101_RS10995	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CB0101_RS11010	COG1587	Uroporphyrinogen-III synthase
CB0101_RS11015	COG0457	Tetratricopeptide repeat
CB0101_RS11015	COG0463	Glycosyl transferase, family 2
CB0101_RS11025	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CB0101_RS11035	COG0625	glutathione transferase activity
CB0101_RS11050	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CB0101_RS11080	COG1032	radical SAM domain protein
CB0101_RS11095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CB0101_RS11100	COG4243	Vitamin k epoxide reductase
CB0101_RS11105	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CB0101_RS11110	COG1555	photosystem II stabilization
CB0101_RS11120	COG1968	undecaprenyl-diphosphatase activity
CB0101_RS11140	COG0483	inositol monophosphate 1-phosphatase activity
CB0101_RS11175	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CB0101_RS11185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CB0101_RS11200	COG0514	ATP-dependent DNA helicase (RecQ)
CB0101_RS11205	COG1388	LysM domain
CB0101_RS11205	COG3942	CHAP domain
CB0101_RS11210	COG1012	belongs to the aldehyde dehydrogenase family
CB0101_RS11220	COG4191	Histidine kinase
CB0101_RS11240	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CB0101_RS11310	COG0745	RESPONSE REGULATOR receiver
CB0101_RS11315	COG5002	protein histidine kinase activity
CB0101_RS11380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CB0101_RS11405	COG1970	mechanosensitive ion channel activity
CB0101_RS11420	COG2197	response regulator
CB0101_RS11545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CB0101_RS11560	COG1160	GTP binding
CB0101_RS11565	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CB0101_RS11575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CB0101_RS11580	COG1799	cell septum assembly
CB0101_RS11585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CB0101_RS11590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CB0101_RS11605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CB0101_RS11610	COG2211	Major facilitator Superfamily
CB0101_RS11630	COG0776	regulation of translation
CB0101_RS11650	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CB0101_RS11665	COG0113	porphobilinogen synthase activity
CB0101_RS11690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CB0101_RS11700	COG1193	negative regulation of DNA recombination
CB0101_RS11705	COG3842	ATPase activity
CB0101_RS11710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CB0101_RS11725	COG0488	(ABC) transporter
CB0101_RS11730	COG2801	Transposase and inactivated derivatives
CB0101_RS11750	COG3039	Transposase
CB0101_RS11765	COG2988	succinylglutamate desuccinylase activity
CB0101_RS11925	COG3039	Transposase
CB0101_RS11995	COG0582	viral genome integration into host DNA
CB0101_RS12035	COG1970	mechanosensitive ion channel activity
CB0101_RS12110	COG0745	RESPONSE REGULATOR receiver
CB0101_RS12125	COG0745	RESPONSE REGULATOR receiver
CB0101_RS12140	COG1799	cell septum assembly
CB0101_RS12200	COG2197	response regulator
CB0101_RS12210	COG3659	wide pore channel activity
CB0101_RS12245	COG3039	Transposase
CB0101_RS12310	COG0582	viral genome integration into host DNA
CB0101_RS12345	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CB0101_RS12370	COG2337	Toxic component of a toxin-antitoxin (TA) module
CB0101_RS12415	COG3275	phosphorelay sensor kinase activity
CB0101_RS12465	COG4178	(ABC) transporter
CB0101_RS12475	COG0745	RESPONSE REGULATOR receiver
CB0101_RS12485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CB0101_RS12490	COG0271	Belongs to the BolA IbaG family
CB0101_RS12505	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CB0101_RS12525	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CB0101_RS12530	COG1074	ATP-dependent DNA helicase activity
CB0101_RS12535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CB0101_RS12540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CB0101_RS12550	COG0513	Belongs to the DEAD box helicase family
CB0101_RS12560	COG0724	RNA recognition motif
CB0101_RS12575	COG1132	(ABC) transporter
CB0101_RS12590	COG1285	pathogenesis
CB0101_RS12645	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CB0101_RS12650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CB0101_RS12665	COG1054	Belongs to the UPF0176 family
CB0101_RS12670	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CB0101_RS12675	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CB0101_RS12680	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CB0101_RS12685	COG0019	diaminopimelate decarboxylase activity
CB0101_RS12695	COG0542	response to heat
CB0101_RS12755	COG2119	membrane
CB0101_RS12760	COG0371	Dehydrogenase
CB0101_RS12765	COG0596	Alpha beta hydrolase
CB0101_RS12775	COG0575	Belongs to the CDS family
CB0101_RS12780	COG2242	protein methyltransferase activity
CB0101_RS12780	COG2241	protein methyltransferase activity
CB0101_RS12790	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CB0101_RS12800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CB0101_RS12805	COG1187	pseudouridine synthase activity
CB0101_RS12815	COG1640	4-alpha-glucanotransferase
CB0101_RS12820	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
CB0101_RS12835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CB0101_RS12860	COG2205	protein histidine kinase activity
CB0101_RS12875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CB0101_RS12880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CB0101_RS12885	COG3409	Peptidoglycan-binding domain 1 protein
CB0101_RS12885	COG3429	Glucose-6-phosphate dehydrogenase subunit
CB0101_RS12890	COG1797	cobyrinic acid a,c-diamide synthase activity
CB0101_RS12895	COG0406	alpha-ribazole phosphatase activity
CB0101_RS12900	COG1254	Belongs to the acylphosphatase family
CB0101_RS12910	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CB0101_RS12930	COG1480	7TM receptor with intracellular HD hydrolase
CB0101_RS12940	COG4095	Psort location CytoplasmicMembrane, score
CB0101_RS12945	COG0564	pseudouridine synthase activity
CB0101_RS12960	COG1799	cell septum assembly
CB0101_RS13000	COG0395	ABC-type sugar transport system, permease component
CB0101_RS13005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CB0101_RS13015	COG1543	Belongs to the glycosyl hydrolase 57 family
CB0101_RS13025	COG0644	oxidoreductase
CB0101_RS13030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CB0101_RS13045	COG0516	GMP reductase activity
CB0101_RS13050	COG3118	belongs to the thioredoxin family
CB0101_RS13055	COG1611	Belongs to the LOG family
CB0101_RS13060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CB0101_RS13065	COG0116	Belongs to the methyltransferase superfamily
CB0101_RS13065	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CB0101_RS13075	COG2010	Cytochrome c
CB0101_RS13080	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CB0101_RS13095	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CB0101_RS13100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CB0101_RS13120	COG2166	iron-sulfur cluster assembly
CB0101_RS13125	COG0460	homoserine dehydrogenase
CB0101_RS13135	COG0747	negative chemotaxis
CB0101_RS13140	COG0601	transmembrane transport
CB0101_RS13145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CB0101_RS13155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CB0101_RS13160	COG0012	GTP binding
CB0101_RS13170	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CB0101_RS13180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CB0101_RS13185	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CB0101_RS13200	COG0194	GDP metabolic process
CB0101_RS13205	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CB0101_RS13210	COG0805	protein transport
CB0101_RS13220	COG0723	plastoquinol--plastocyanin reductase activity
CB0101_RS13225	COG0739	heme binding
CB0101_RS13255	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CB0101_RS13260	COG1619	proteins homologs of microcin C7 resistance protein MccF
CB0101_RS13265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CB0101_RS13275	COG0569	domain protein
CB0101_RS13280	COG1028	Short-chain dehydrogenase reductase Sdr
CB0101_RS13290	COG0459	protein refolding
CB0101_RS13300	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CB0101_RS13320	COG0109	protoheme IX farnesyltransferase activity
CB0101_RS13335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CB0101_RS13340	COG1845	cytochrome c oxidase, subunit III
CB0101_RS13375	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CB0101_RS13390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CB0101_RS13400	COG1136	(ABC) transporter
CB0101_RS13400	COG0577	efflux transmembrane transporter activity
CB0101_RS13405	COG0739	heme binding
CB0101_RS13410	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CB0101_RS13410	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CB0101_RS13415	COG0436	Aminotransferase
CB0101_RS13420	COG3118	belongs to the thioredoxin family
CB0101_RS13425	COG1842	Phage shock protein A
CB0101_RS13430	COG0668	transmembrane transport
CB0101_RS13445	COG0438	transferase activity, transferring glycosyl groups
CB0101_RS13450	COG0697	spore germination
CB0101_RS13455	COG0616	signal peptide processing
CB0101_RS13470	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CB0101_RS13475	COG0594	ribonuclease P activity
CB0101_RS13485	COG0706	membrane insertase activity
CB0101_RS13560	COG3039	Transposase
CB0101_RS13565	COG4974	Belongs to the 'phage' integrase family
CB0101_RS13570	COG1104	cysteine desulfurase activity
CB0101_RS13575	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CB0101_RS13585	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CB0101_RS13600	COG0134	indole-3-glycerol-phosphate synthase activity
CB0101_RS13605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CB0101_RS13610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CB0101_RS13625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CB0101_RS13630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CB0101_RS13635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CB0101_RS13675	COG4948	Mandelate Racemase Muconate Lactonizing
CB0101_RS13680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CB0101_RS13685	COG1181	Belongs to the D-alanine--D-alanine ligase family
CB0101_RS13700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CB0101_RS13710	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CB0101_RS13715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CB0101_RS13720	COG4956	integral membrane protein (PIN domain superfamily)
CB0101_RS13725	COG0740	serine-type endopeptidase activity
CB0101_RS13730	COG0740	serine-type endopeptidase activity
CB0101_RS13735	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CB0101_RS13740	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CB0101_RS13745	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CB0101_RS13750	COG0438	transferase activity, transferring glycosyl groups
CB0101_RS13780	COG0752	glycyl-tRNA synthetase alpha subunit
CB0101_RS13785	COG2226	methyltransferase
CB0101_RS13795	COG0107	imidazoleglycerol-phosphate synthase activity
CB0101_RS13805	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CB0101_RS13815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CB0101_RS13815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CB0101_RS13820	COG3695	enzyme binding
CB0101_RS13825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CB0101_RS13845	COG0745	RESPONSE REGULATOR receiver
CB0101_RS13860	COG5002	protein histidine kinase activity
CB0101_RS13870	COG3039	Transposase
CB0101_RS13880	COG2801	Transposase and inactivated derivatives
CB0101_RS13895	COG4968	Prepilin-type N-terminal cleavage methylation domain
CB0101_RS13945	COG0481	GTPase activity
CB0101_RS13955	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CB0101_RS13960	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CB0101_RS13965	COG0579	oxidoreductase
CB0101_RS13970	COG0750	zinc metalloprotease
CB0101_RS13975	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CB0101_RS13980	COG1185	polyribonucleotide nucleotidyltransferase activity
CB0101_RS13985	COG1218	3'(2'),5'-bisphosphate nucleotidase
CB0101_RS13990	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CB0101_RS14050	COG0484	heat shock protein binding
CB0101_RS14055	COG4243	Vitamin k epoxide reductase
CB0101_RS14065	COG0393	Putative heavy-metal-binding
CB0101_RS14080	COG0116	Belongs to the methyltransferase superfamily
CB0101_RS14085	COG3263	regulation of cellular component size
CB0101_RS14110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CB0101_RS14125	COG0439	Biotin carboxylase
CB0101_RS14140	COG0515	serine threonine protein kinase
CB0101_RS14160	COG4178	(ABC) transporter
CB0101_RS14165	COG0537	adenosine 5'-monophosphoramidase activity
CB0101_RS14175	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CB0101_RS14190	COG0242	peptide deformylase activity
CB0101_RS14210	COG0235	Class ii aldolase
CB0101_RS14215	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CB0101_RS14230	COG1231	oxidoreductase activity
CB0101_RS14245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CB0101_RS14250	COG0719	Fe-S assembly protein
CB0101_RS14255	COG0396	ATPase activity
CB0101_RS14260	COG0719	Fe-S assembly protein
CB0101_RS14265	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
CB0101_RS14290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CB0101_RS14305	COG0457	Tetratricopeptide repeat
CB0101_RS14315	COG0033	Phosphoglucomutase
CB0101_RS14340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CB0101_RS14350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CB0101_RS14375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CB0101_RS14380	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CB0101_RS14385	COG0175	sulfate reduction
CB0101_RS14390	COG1252	NADH dehydrogenase
CB0101_RS14400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CB0101_RS14410	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CB0101_RS14420	COG0488	(ABC) transporter
CB0101_RS14430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CB0101_RS14445	COG1643	Atp-dependent helicase
CB0101_RS14465	COG1570	exodeoxyribonuclease VII activity
CB0101_RS14520	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CB0101_RS14525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CB0101_RS14530	COG0793	Belongs to the peptidase S41A family
CB0101_RS14535	COG1078	dGTPase activity
CB0101_RS14540	COG0850	regulation of cytokinetic process
CB0101_RS14560	COG2894	cell division
CB0101_RS14565	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CB0101_RS14600	COG1122	ATPase activity
CB0101_RS14610	COG0745	RESPONSE REGULATOR receiver
CB0101_RS14615	COG0470	DNA polymerase III
CB0101_RS14620	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CB0101_RS14625	COG2217	Heavy metal translocating P-type atpase
CB0101_RS14630	COG0457	Tetratricopeptide repeat
CB0101_RS14635	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CB0101_RS14640	COG0745	RESPONSE REGULATOR receiver
CB0101_RS14645	COG0416	fatty acid biosynthetic process
CB0101_RS14650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CB0101_RS14655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CB0101_RS14670	COG1214	PFAM Peptidase M22, glycoprotease
CB0101_RS14680	COG0617	tRNA 3'-terminal CCA addition
CB0101_RS14685	COG0724	RNA recognition motif
CB0101_RS14695	COG1562	ergosterol biosynthetic process
CB0101_RS14700	COG0493	'glutamate synthase
CB0101_RS14700	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CB0101_RS14715	COG0583	DNA-binding transcription factor activity
CB0101_RS14725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CB0101_RS14735	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CB0101_RS14750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CB0101_RS14770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CB0101_RS14775	COG0713	ATP synthesis coupled electron transport
CB0101_RS14780	COG0839	Belongs to the complex I subunit 6 family
CB0101_RS14785	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CB0101_RS14790	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CB0101_RS14795	COG0372	Belongs to the citrate synthase family
CB0101_RS14800	COG2062	phosphohistidine phosphatase, SixA
CB0101_RS14810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CB0101_RS14815	COG1420	regulation of RNA biosynthetic process
CB0101_RS14820	COG0133	tryptophan synthase activity
CB0101_RS14830	COG0023	Translation Initiation Factor
CB0101_RS14835	COG0750	zinc metalloprotease
CB0101_RS14840	COG0529	Catalyzes the synthesis of activated sulfate
CB0101_RS14845	COG0628	permease
CB0101_RS14855	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CB0101_RS14860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CB0101_RS14865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CB0101_RS14875	COG0564	pseudouridine synthase activity
CB0101_RS14880	COG0745	RESPONSE REGULATOR receiver
CB0101_RS14890	COG1104	cysteine desulfurase activity
CB0101_RS14905	COG0275	rRNA processing
CB0101_RS14910	COG0649	NAD binding
CB0101_RS14920	COG0824	Thioesterase
CB0101_RS14930	COG0318	PFAM AMP-dependent synthetase and ligase
CB0101_RS14940	COG1575	Belongs to the MenA family. Type 1 subfamily
CB0101_RS14950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CB0101_RS14955	COG0189	ligase activity
CB0101_RS14960	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CB0101_RS14985	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CB0101_RS14990	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CB0101_RS15005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CB0101_RS15010	COG0018	arginyl-trna synthetase
CB0101_RS15015	COG0515	serine threonine protein kinase
CB0101_RS15030	COG0157	Belongs to the NadC ModD family
CB0101_RS15035	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CB0101_RS15045	COG4106	trans-aconitate 2-methyltransferase activity
CB0101_RS15060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CB0101_RS15065	COG4172	Belongs to the ABC transporter superfamily
CB0101_RS15070	COG0564	pseudouridine synthase activity
CB0101_RS15080	COG0589	response to stress
CB0101_RS15085	COG0126	phosphoglycerate kinase activity
CB0101_RS15110	COG2084	Dehydrogenase
CB0101_RS15120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CB0101_RS15135	COG1450	Type ii and iii secretion system protein