locus-tag	class	description
SYNCC9902_RS00010	COG0592	DNA-directed DNA polymerase activity
SYNCC9902_RS00020	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SYNCC9902_RS00025	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SYNCC9902_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SYNCC9902_RS00040	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SYNCC9902_RS00055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SYNCC9902_RS00060	COG0552	protein localization to endoplasmic reticulum
SYNCC9902_RS00065	COG2208	phosphoserine phosphatase activity
SYNCC9902_RS00070	COG0165	Argininosuccinate lyase
SYNCC9902_RS00080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SYNCC9902_RS00085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SYNCC9902_RS00090	COG2081	HI0933 family
SYNCC9902_RS00100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SYNCC9902_RS00105	COG0484	heat shock protein binding
SYNCC9902_RS00115	COG1162	GTPase activity
SYNCC9902_RS00120	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SYNCC9902_RS00125	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SYNCC9902_RS00130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SYNCC9902_RS00135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SYNCC9902_RS00140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SYNCC9902_RS00145	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SYNCC9902_RS00150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SYNCC9902_RS00155	COG0511	ligase activity, forming carbon-carbon bonds
SYNCC9902_RS00160	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SYNCC9902_RS00210	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
SYNCC9902_RS00215	COG0519	Catalyzes the synthesis of GMP from XMP
SYNCC9902_RS00215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SYNCC9902_RS00220	COG2226	methyltransferase
SYNCC9902_RS00245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SYNCC9902_RS00245	COG0438	transferase activity, transferring glycosyl groups
SYNCC9902_RS00250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SYNCC9902_RS00260	COG2022	thiamine diphosphate biosynthetic process
SYNCC9902_RS00275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SYNCC9902_RS00280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SYNCC9902_RS00285	COG2385	sporulation resulting in formation of a cellular spore
SYNCC9902_RS00290	COG1215	transferase activity, transferring glycosyl groups
SYNCC9902_RS00295	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SYNCC9902_RS00310	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SYNCC9902_RS00315	COG0740	serine-type endopeptidase activity
SYNCC9902_RS00320	COG0544	peptidyl-prolyl cis-trans isomerase activity
SYNCC9902_RS00325	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SYNCC9902_RS00330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SYNCC9902_RS00335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SYNCC9902_RS00360	COG0527	aspartate kinase activity
SYNCC9902_RS00370	COG2082	Precorrin-8x methylmutase
SYNCC9902_RS00375	COG0037	tRNA processing
SYNCC9902_RS00390	COG0556	nucleotide-excision repair
SYNCC9902_RS00410	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SYNCC9902_RS00445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SYNCC9902_RS00450	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
SYNCC9902_RS00475	COG1086	Polysaccharide biosynthesis protein
SYNCC9902_RS00485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SYNCC9902_RS00550	COG0653	protein targeting
SYNCC9902_RS00580	COG1045	serine acetyltransferase
SYNCC9902_RS00585	COG1725	Transcriptional regulator
SYNCC9902_RS00590	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SYNCC9902_RS00595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SYNCC9902_RS00600	COG1372	Participates in initiation and elongation during chromosome replication
SYNCC9902_RS00600	COG0187	DNA topoisomerase II activity
SYNCC9902_RS00610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SYNCC9902_RS00615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SYNCC9902_RS00620	COG0386	Belongs to the glutathione peroxidase family
SYNCC9902_RS00625	COG2239	Acts as a magnesium transporter
SYNCC9902_RS00630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYNCC9902_RS00635	COG0596	Alpha beta hydrolase
SYNCC9902_RS00640	COG3239	Fatty acid desaturase
SYNCC9902_RS00660	COG0802	atpase or kinase
SYNCC9902_RS00665	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
SYNCC9902_RS00670	COG0586	Pfam SNARE associated Golgi protein
SYNCC9902_RS00675	COG0629	single-stranded DNA binding
SYNCC9902_RS00700	COG0745	RESPONSE REGULATOR receiver
SYNCC9902_RS00705	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SYNCC9902_RS00725	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
SYNCC9902_RS00730	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SYNCC9902_RS00735	COG0515	serine threonine protein kinase
SYNCC9902_RS00740	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SYNCC9902_RS00745	COG2255	four-way junction helicase activity
SYNCC9902_RS00755	COG1473	amidohydrolase
SYNCC9902_RS00770	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SYNCC9902_RS00775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SYNCC9902_RS00780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SYNCC9902_RS00785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SYNCC9902_RS00790	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNCC9902_RS00795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SYNCC9902_RS00800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SYNCC9902_RS00810	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
SYNCC9902_RS00810	COG0662	Cupin 2, conserved barrel domain protein
SYNCC9902_RS00815	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SYNCC9902_RS00825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SYNCC9902_RS00830	COG0571	ribonuclease III activity
SYNCC9902_RS00855	COG0058	SHG alpha-glucan phosphorylase activity
SYNCC9902_RS00860	COG0475	glutathione-regulated potassium exporter activity
SYNCC9902_RS00880	COG0277	FAD linked oxidase domain protein
SYNCC9902_RS00890	COG0247	lactate metabolic process
SYNCC9902_RS00900	COG0538	isocitrate dehydrogenase activity
SYNCC9902_RS00905	COG0463	Glycosyl transferase, family 2
SYNCC9902_RS00925	COG5398	heme oxygenase
SYNCC9902_RS00940	COG0438	transferase activity, transferring glycosyl groups
SYNCC9902_RS00945	COG0438	transferase activity, transferring glycosyl groups
SYNCC9902_RS00950	COG0438	transferase activity, transferring glycosyl groups
SYNCC9902_RS00955	COG0438	transferase activity, transferring glycosyl groups
SYNCC9902_RS00975	COG2877	3-deoxy-8-phosphooctulonate synthase activity
SYNCC9902_RS00990	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
SYNCC9902_RS00995	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
SYNCC9902_RS01000	COG0517	IMP dehydrogenase activity
SYNCC9902_RS01000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SYNCC9902_RS01005	COG0517	IMP dehydrogenase activity
SYNCC9902_RS01005	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SYNCC9902_RS01005	COG0617	tRNA 3'-terminal CCA addition
SYNCC9902_RS01015	COG0709	Synthesizes selenophosphate from selenide and ATP
SYNCC9902_RS01020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SYNCC9902_RS01030	COG2274	protein secretion by the type I secretion system
SYNCC9902_RS01035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SYNCC9902_RS01045	COG0124	histidyl-tRNA synthetase
SYNCC9902_RS01055	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SYNCC9902_RS01085	COG4447	cellulose binding
SYNCC9902_RS01090	COG1773	rubredoxin
SYNCC9902_RS01095	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNCC9902_RS01100	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNCC9902_RS01105	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNCC9902_RS01110	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SYNCC9902_RS01125	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SYNCC9902_RS01125	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SYNCC9902_RS01135	COG0494	nUDIX hydrolase
SYNCC9902_RS01140	COG0415	Belongs to the DNA photolyase family
SYNCC9902_RS01175	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SYNCC9902_RS01180	COG0131	Imidazoleglycerol-phosphate dehydratase
SYNCC9902_RS01185	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
SYNCC9902_RS01200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SYNCC9902_RS01220	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SYNCC9902_RS01225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SYNCC9902_RS01235	COG0354	folic acid binding
SYNCC9902_RS01240	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SYNCC9902_RS01255	COG1253	flavin adenine dinucleotide binding
SYNCC9902_RS01260	COG0673	inositol 2-dehydrogenase activity
SYNCC9902_RS01280	COG0343	queuine tRNA-ribosyltransferase activity
SYNCC9902_RS01310	COG0138	bifunctional purine biosynthesis protein purh
SYNCC9902_RS01325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SYNCC9902_RS01330	COG0004	ammonium transporteR
SYNCC9902_RS01335	COG1489	DNA binding
SYNCC9902_RS01340	COG0728	peptidoglycan biosynthetic process
SYNCC9902_RS01345	COG0372	Belongs to the citrate synthase family
SYNCC9902_RS01350	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
SYNCC9902_RS01355	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNCC9902_RS01365	COG0713	ATP synthesis coupled electron transport
SYNCC9902_RS01370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SYNCC9902_RS01380	COG2197	response regulator
SYNCC9902_RS01390	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
SYNCC9902_RS01405	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNCC9902_RS01410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SYNCC9902_RS01420	COG0583	DNA-binding transcription factor activity
SYNCC9902_RS01435	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SYNCC9902_RS01435	COG0493	'glutamate synthase
SYNCC9902_RS01440	COG1562	ergosterol biosynthetic process
SYNCC9902_RS01445	COG0724	RNA recognition motif
SYNCC9902_RS01450	COG0617	tRNA 3'-terminal CCA addition
SYNCC9902_RS01460	COG1214	PFAM Peptidase M22, glycoprotease
SYNCC9902_RS01475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SYNCC9902_RS01480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SYNCC9902_RS01485	COG0416	fatty acid biosynthetic process
SYNCC9902_RS01495	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SYNCC9902_RS01500	COG3063	Type IV pilus biogenesis stability protein PilW
SYNCC9902_RS01505	COG2217	Heavy metal translocating P-type atpase
SYNCC9902_RS01510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SYNCC9902_RS01520	COG0745	RESPONSE REGULATOR receiver
SYNCC9902_RS01530	COG1122	ATPase activity
SYNCC9902_RS01570	COG3659	wide pore channel activity
SYNCC9902_RS01575	COG3659	wide pore channel activity
SYNCC9902_RS01580	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SYNCC9902_RS01585	COG0484	heat shock protein binding
SYNCC9902_RS01600	COG3263	regulation of cellular component size
SYNCC9902_RS01605	COG1090	epimerase
SYNCC9902_RS01625	COG0316	Belongs to the HesB IscA family
SYNCC9902_RS01630	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
SYNCC9902_RS01645	COG1587	Uroporphyrinogen-III synthase
SYNCC9902_RS01650	COG0457	Tetratricopeptide repeat
SYNCC9902_RS01650	COG0463	Glycosyl transferase, family 2
SYNCC9902_RS01655	COG1472	Belongs to the glycosyl hydrolase 3 family
SYNCC9902_RS01660	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SYNCC9902_RS01685	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SYNCC9902_RS01700	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SYNCC9902_RS01725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SYNCC9902_RS01730	COG4243	Vitamin k epoxide reductase
SYNCC9902_RS01735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SYNCC9902_RS01740	COG1555	photosystem II stabilization
SYNCC9902_RS01750	COG1968	undecaprenyl-diphosphatase activity
SYNCC9902_RS01810	COG1722	exodeoxyribonuclease VII activity
SYNCC9902_RS01815	COG1570	exodeoxyribonuclease VII activity
SYNCC9902_RS01830	COG1643	Atp-dependent helicase
SYNCC9902_RS01845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SYNCC9902_RS01850	COG0488	(ABC) transporter
SYNCC9902_RS01875	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
SYNCC9902_RS01880	COG0569	domain protein
SYNCC9902_RS01885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SYNCC9902_RS01890	COG0471	metal ion transport
SYNCC9902_RS01890	COG3273	potassium ion transport
SYNCC9902_RS01895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SYNCC9902_RS01900	COG1252	NADH dehydrogenase
SYNCC9902_RS01905	COG0175	sulfate reduction
SYNCC9902_RS01910	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SYNCC9902_RS01915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SYNCC9902_RS01925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SYNCC9902_RS01935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SYNCC9902_RS01945	COG0033	Phosphoglucomutase
SYNCC9902_RS01980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SYNCC9902_RS02000	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
SYNCC9902_RS02005	COG0719	Fe-S assembly protein
SYNCC9902_RS02010	COG0396	ATPase activity
SYNCC9902_RS02015	COG0719	Fe-S assembly protein
SYNCC9902_RS02020	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SYNCC9902_RS02030	COG0242	peptide deformylase activity
SYNCC9902_RS02045	COG0606	chelatase, subunit chli
SYNCC9902_RS02050	COG0537	adenosine 5'-monophosphoramidase activity
SYNCC9902_RS02055	COG4178	(ABC) transporter
SYNCC9902_RS02075	COG0515	serine threonine protein kinase
SYNCC9902_RS02090	COG0439	Biotin carboxylase
SYNCC9902_RS02105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SYNCC9902_RS02115	COG1196	nuclear chromosome segregation
SYNCC9902_RS02135	COG0116	Belongs to the methyltransferase superfamily
SYNCC9902_RS02245	COG0513	Belongs to the DEAD box helicase family
SYNCC9902_RS02290	COG2089	acid synthase
SYNCC9902_RS02310	COG1083	cytidylyl-transferase
SYNCC9902_RS02320	COG3562	capsule polysaccharide
SYNCC9902_RS02330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SYNCC9902_RS02345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SYNCC9902_RS02355	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SYNCC9902_RS02360	COG1333	cytochrome c biogenesis protein
SYNCC9902_RS02370	COG0772	Belongs to the SEDS family
SYNCC9902_RS02405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SYNCC9902_RS02410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SYNCC9902_RS02420	COG0356	it plays a direct role in the translocation of protons across the membrane
SYNCC9902_RS02425	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SYNCC9902_RS02430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SYNCC9902_RS02435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SYNCC9902_RS02440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SYNCC9902_RS02445	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SYNCC9902_RS02450	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SYNCC9902_RS02460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SYNCC9902_RS02470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SYNCC9902_RS02475	COG3012	SEC-C Motif Domain Protein
SYNCC9902_RS02480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SYNCC9902_RS02480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SYNCC9902_RS02485	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SYNCC9902_RS02490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SYNCC9902_RS02505	COG1253	flavin adenine dinucleotide binding
SYNCC9902_RS02510	COG0006	proline dipeptidase activity
SYNCC9902_RS02525	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SYNCC9902_RS02530	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SYNCC9902_RS02535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SYNCC9902_RS02540	COG0459	protein refolding
SYNCC9902_RS02575	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SYNCC9902_RS02580	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
SYNCC9902_RS02595	COG0443	Heat shock 70 kDa protein
SYNCC9902_RS02630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SYNCC9902_RS02650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SYNCC9902_RS02655	COG2264	protein methyltransferase activity
SYNCC9902_RS02670	COG2010	Cytochrome c
SYNCC9902_RS02675	COG1234	tRNA 3'-trailer cleavage
SYNCC9902_RS02680	COG2247	cell wall binding repeat
SYNCC9902_RS02680	COG2385	sporulation resulting in formation of a cellular spore
SYNCC9902_RS02685	COG0363	glucosamine-6-phosphate deaminase activity
SYNCC9902_RS02730	COG0217	transcriptional regulatory protein
SYNCC9902_RS02735	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SYNCC9902_RS02740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SYNCC9902_RS02745	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SYNCC9902_RS02750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SYNCC9902_RS02760	COG4251	negative regulation of phosphorylation
SYNCC9902_RS02765	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
SYNCC9902_RS02770	COG5002	protein histidine kinase activity
SYNCC9902_RS02775	COG0151	Belongs to the GarS family
SYNCC9902_RS02785	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SYNCC9902_RS02795	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
SYNCC9902_RS02800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SYNCC9902_RS02805	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SYNCC9902_RS02810	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SYNCC9902_RS02815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SYNCC9902_RS02830	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SYNCC9902_RS02850	COG2197	response regulator
SYNCC9902_RS02860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SYNCC9902_RS02865	COG3386	PFAM SMP-30 Gluconolaconase
SYNCC9902_RS02875	COG0284	orotidine-5'-phosphate decarboxylase activity
SYNCC9902_RS02885	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SYNCC9902_RS02900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
SYNCC9902_RS02905	COG2211	Major facilitator Superfamily
SYNCC9902_RS02925	COG0776	regulation of translation
SYNCC9902_RS02930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SYNCC9902_RS02960	COG1053	succinate dehydrogenase
SYNCC9902_RS03000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SYNCC9902_RS03010	COG0195	Participates in both transcription termination and antitermination
SYNCC9902_RS03015	COG0779	Required for maturation of 30S ribosomal subunits
SYNCC9902_RS03025	COG0641	radical SAM
SYNCC9902_RS03040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SYNCC9902_RS03045	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
SYNCC9902_RS03050	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SYNCC9902_RS03055	COG0268	Binds directly to 16S ribosomal RNA
SYNCC9902_RS03060	COG0084	hydrolase, TatD family'
SYNCC9902_RS03065	COG0085	RNA polymerase activity
SYNCC9902_RS03070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SYNCC9902_RS03075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SYNCC9902_RS03080	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SYNCC9902_RS03085	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SYNCC9902_RS03120	COG0357	Ribosomal RNA small subunit methyltransferase G
SYNCC9902_RS03135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SYNCC9902_RS03145	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SYNCC9902_RS03160	COG0156	8-amino-7-oxononanoate synthase activity
SYNCC9902_RS03165	COG0385	Bile acid
SYNCC9902_RS03175	COG4581	dead DEAH box helicase
SYNCC9902_RS03180	COG0114	fumarate hydratase activity
SYNCC9902_RS03205	COG3754	Rhamnan synthesis protein F
SYNCC9902_RS03225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SYNCC9902_RS03230	COG1216	Glycosyl transferase, family 2
SYNCC9902_RS03230	COG0438	transferase activity, transferring glycosyl groups
SYNCC9902_RS03245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SYNCC9902_RS03255	COG1160	GTP binding
SYNCC9902_RS03260	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SYNCC9902_RS03270	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SYNCC9902_RS03275	COG1799	cell septum assembly
SYNCC9902_RS03280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SYNCC9902_RS03290	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SYNCC9902_RS03305	COG0438	transferase activity, transferring glycosyl groups
SYNCC9902_RS03315	COG1381	Involved in DNA repair and RecF pathway recombination
SYNCC9902_RS03320	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SYNCC9902_RS03325	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SYNCC9902_RS03330	COG0321	lipoyl(octanoyl) transferase activity
SYNCC9902_RS03335	COG1022	Amp-dependent synthetase and ligase
SYNCC9902_RS03345	COG0508	dehydrogenase complex catalyzes the overall conversion of
SYNCC9902_RS03350	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SYNCC9902_RS03355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SYNCC9902_RS03365	COG0626	cystathionine gamma-synthase activity
SYNCC9902_RS03385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SYNCC9902_RS03390	COG0440	acetolactate synthase activity
SYNCC9902_RS03395	COG2267	carboxylic ester hydrolase activity
SYNCC9902_RS03420	COG2226	methyltransferase
SYNCC9902_RS03425	COG1187	pseudouridine synthase activity
SYNCC9902_RS03430	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SYNCC9902_RS03475	COG3411	Ferredoxin
SYNCC9902_RS03480	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SYNCC9902_RS03485	COG0733	neurotransmitter:sodium symporter activity
SYNCC9902_RS03495	COG0215	cysteine-tRNA ligase activity
SYNCC9902_RS03500	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SYNCC9902_RS03500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SYNCC9902_RS03505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SYNCC9902_RS03510	COG0012	GTP binding
SYNCC9902_RS03525	COG2814	Major facilitator Superfamily
SYNCC9902_RS03535	COG0601	transmembrane transport
SYNCC9902_RS03550	COG0460	homoserine dehydrogenase
SYNCC9902_RS03555	COG2166	iron-sulfur cluster assembly
SYNCC9902_RS03565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SYNCC9902_RS03595	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
SYNCC9902_RS03600	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
SYNCC9902_RS03620	COG2010	Cytochrome c
SYNCC9902_RS03630	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SYNCC9902_RS03635	COG3118	belongs to the thioredoxin family
SYNCC9902_RS03640	COG0516	GMP reductase activity
SYNCC9902_RS03650	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SYNCC9902_RS03655	COG0644	oxidoreductase
SYNCC9902_RS03665	COG1543	Belongs to the glycosyl hydrolase 57 family
SYNCC9902_RS03670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SYNCC9902_RS03675	COG0395	ABC-type sugar transport system, permease component
SYNCC9902_RS03700	COG0011	TIGRFAM Protein of
SYNCC9902_RS03710	COG0564	pseudouridine synthase activity
SYNCC9902_RS03715	COG1480	7TM receptor with intracellular HD hydrolase
SYNCC9902_RS03720	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SYNCC9902_RS03740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SYNCC9902_RS03750	COG0406	alpha-ribazole phosphatase activity
SYNCC9902_RS03760	COG1254	Belongs to the acylphosphatase family
SYNCC9902_RS03765	COG1797	cobyrinic acid a,c-diamide synthase activity
SYNCC9902_RS03775	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SYNCC9902_RS03795	COG2205	protein histidine kinase activity
SYNCC9902_RS03810	COG0308	aminopeptidase N
SYNCC9902_RS03855	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SYNCC9902_RS03865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SYNCC9902_RS03880	COG2091	lysine biosynthetic process via aminoadipic acid
SYNCC9902_RS03900	COG1376	ErfK ybiS ycfS ynhG family protein
SYNCC9902_RS03910	COG2239	Acts as a magnesium transporter
SYNCC9902_RS03925	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SYNCC9902_RS03935	COG2197	response regulator
SYNCC9902_RS03940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SYNCC9902_RS03955	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SYNCC9902_RS03970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SYNCC9902_RS03975	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
SYNCC9902_RS03980	COG0473	3-isopropylmalate dehydrogenase activity
SYNCC9902_RS03985	COG3954	Phosphoribulokinase
SYNCC9902_RS04000	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SYNCC9902_RS04010	COG0673	inositol 2-dehydrogenase activity
SYNCC9902_RS04015	COG3588	fructose-bisphosphate aldolase
SYNCC9902_RS04020	COG0191	fructose-bisphosphate aldolase activity
SYNCC9902_RS04025	COG0405	Gamma-glutamyltransferase
SYNCC9902_RS04030	COG1619	proteins homologs of microcin C7 resistance protein MccF
SYNCC9902_RS04035	COG0047	phosphoribosylformylglycinamidine synthase activity
SYNCC9902_RS04040	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SYNCC9902_RS04045	COG0668	transmembrane transport
SYNCC9902_RS04135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SYNCC9902_RS04150	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SYNCC9902_RS04160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SYNCC9902_RS04165	COG1429	ligase activity, forming nitrogen-metal bonds
SYNCC9902_RS04175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SYNCC9902_RS04180	COG0149	triose-phosphate isomerase activity
SYNCC9902_RS04190	COG1132	(ABC) transporter
SYNCC9902_RS04200	COG1115	amino acid carrier protein
SYNCC9902_RS04210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SYNCC9902_RS04220	COG0799	negative regulation of ribosome biogenesis
SYNCC9902_RS04265	COG0659	secondary active sulfate transmembrane transporter activity
SYNCC9902_RS04275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SYNCC9902_RS04280	COG4597	amino acid ABC transporter
SYNCC9902_RS04285	COG0765	amino acid transport
SYNCC9902_RS04290	COG1126	abc transporter atp-binding protein
SYNCC9902_RS04310	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SYNCC9902_RS04315	COG2873	o-acetylhomoserine
SYNCC9902_RS04345	COG0625	glutathione transferase activity
SYNCC9902_RS04380	COG0735	belongs to the Fur family
SYNCC9902_RS04420	COG0251	oxidation-reduction process
SYNCC9902_RS04430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SYNCC9902_RS04435	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SYNCC9902_RS04440	COG1132	(ABC) transporter
SYNCC9902_RS04445	COG0456	acetyltransferase
SYNCC9902_RS04460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SYNCC9902_RS04465	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SYNCC9902_RS04480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SYNCC9902_RS04490	COG0659	secondary active sulfate transmembrane transporter activity
SYNCC9902_RS04495	COG0418	dihydroorotase activity
SYNCC9902_RS04520	COG0159	tryptophan synthase activity
SYNCC9902_RS04535	COG2010	Cytochrome c
SYNCC9902_RS04565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYNCC9902_RS04585	COG0140	phosphoribosyl-ATP diphosphatase activity
SYNCC9902_RS04585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SYNCC9902_RS04595	COG0542	response to heat
SYNCC9902_RS04615	COG2010	Cytochrome c
SYNCC9902_RS04620	COG3794	PFAM blue (type 1) copper domain protein
SYNCC9902_RS04630	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SYNCC9902_RS04635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SYNCC9902_RS04675	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SYNCC9902_RS04690	COG0339	signal peptide processing
SYNCC9902_RS04695	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNCC9902_RS04700	COG0083	homoserine kinase activity
SYNCC9902_RS04705	COG0837	glucose binding
SYNCC9902_RS04715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SYNCC9902_RS04730	COG0180	Tryptophanyl-tRNA synthetase
SYNCC9902_RS04840	COG2124	cytochrome p450
SYNCC9902_RS04850	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SYNCC9902_RS04920	COG2197	response regulator
SYNCC9902_RS04925	COG0724	RNA recognition motif
SYNCC9902_RS05030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SYNCC9902_RS05045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SYNCC9902_RS05065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SYNCC9902_RS05070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SYNCC9902_RS05075	COG0803	Belongs to the bacterial solute-binding protein 9 family
SYNCC9902_RS05080	COG1121	(ABC) transporter
SYNCC9902_RS05090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SYNCC9902_RS05185	COG2226	methyltransferase
SYNCC9902_RS05210	COG1201	RNA secondary structure unwinding
SYNCC9902_RS05215	COG1793	dna ligase
SYNCC9902_RS05230	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SYNCC9902_RS05260	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SYNCC9902_RS05265	COG1175	transmembrane transport
SYNCC9902_RS05270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SYNCC9902_RS05285	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SYNCC9902_RS05305	COG0740	serine-type endopeptidase activity
SYNCC9902_RS05310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYNCC9902_RS05315	COG1136	(ABC) transporter
SYNCC9902_RS05315	COG0577	efflux transmembrane transporter activity
SYNCC9902_RS05320	COG0469	pyruvate kinase activity
SYNCC9902_RS05345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SYNCC9902_RS05350	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SYNCC9902_RS05355	COG0644	oxidoreductase
SYNCC9902_RS05385	COG0395	ABC-type sugar transport system, permease component
SYNCC9902_RS05390	COG1175	transmembrane transport
SYNCC9902_RS05395	COG1653	transport
SYNCC9902_RS05400	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
SYNCC9902_RS05405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SYNCC9902_RS05410	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SYNCC9902_RS05415	COG0326	Molecular chaperone. Has ATPase activity
SYNCC9902_RS05430	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SYNCC9902_RS05435	COG0483	inositol monophosphate 1-phosphatase activity
SYNCC9902_RS05460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SYNCC9902_RS05465	COG0581	inorganic phosphate transmembrane transporter activity
SYNCC9902_RS05470	COG0573	inorganic phosphate transmembrane transporter activity
SYNCC9902_RS05475	COG0443	Heat shock 70 kDa protein
SYNCC9902_RS05480	COG0484	heat shock protein binding
SYNCC9902_RS05490	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SYNCC9902_RS05495	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SYNCC9902_RS05500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SYNCC9902_RS05505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SYNCC9902_RS05505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SYNCC9902_RS05510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SYNCC9902_RS05515	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SYNCC9902_RS05540	COG0166	Belongs to the GPI family
SYNCC9902_RS05545	COG0495	leucyl-tRNA aminoacylation
SYNCC9902_RS05555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SYNCC9902_RS05560	COG1104	cysteine desulfurase activity
SYNCC9902_RS05575	COG2027	D-alanyl-D-alanine carboxypeptidase
SYNCC9902_RS05585	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SYNCC9902_RS05595	COG0322	excinuclease ABC activity
SYNCC9902_RS05605	COG3046	protein related to deoxyribodipyrimidine photolyase
SYNCC9902_RS05610	COG1981	membrane
SYNCC9902_RS05630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SYNCC9902_RS05635	COG1410	methionine synthase
SYNCC9902_RS05635	COG0646	methionine synthase
SYNCC9902_RS05665	COG2385	sporulation resulting in formation of a cellular spore
SYNCC9902_RS05700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SYNCC9902_RS05705	COG0072	phenylalanine-tRNA ligase activity
SYNCC9902_RS05710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SYNCC9902_RS05715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SYNCC9902_RS05720	COG0557	exoribonuclease II activity
SYNCC9902_RS05730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SYNCC9902_RS05765	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SYNCC9902_RS05770	COG0739	heme binding
SYNCC9902_RS05780	COG0450	alkyl hydroperoxide reductase
SYNCC9902_RS05785	COG1615	UPF0182 protein
SYNCC9902_RS05790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYNCC9902_RS05795	COG0333	Belongs to the bacterial ribosomal protein bL32 family
SYNCC9902_RS05810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SYNCC9902_RS05815	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SYNCC9902_RS05815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SYNCC9902_RS05830	COG2119	membrane
SYNCC9902_RS05840	COG0557	exoribonuclease II activity
SYNCC9902_RS05845	COG0163	prenyltransferase activity
SYNCC9902_RS05860	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SYNCC9902_RS05865	COG0312	modulator of DNA gyrase
SYNCC9902_RS05875	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SYNCC9902_RS05890	COG0861	Integral membrane protein TerC family
SYNCC9902_RS05905	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SYNCC9902_RS05910	COG0793	Belongs to the peptidase S41A family
SYNCC9902_RS05915	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SYNCC9902_RS05920	COG1573	uracil-dna glycosylase
SYNCC9902_RS05930	COG0436	Aminotransferase
SYNCC9902_RS05935	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
SYNCC9902_RS05940	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
SYNCC9902_RS05960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYNCC9902_RS05965	COG1836	PFAM Integral membrane protein DUF92
SYNCC9902_RS05985	COG1129	ABC transporter
SYNCC9902_RS05990	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SYNCC9902_RS06005	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
SYNCC9902_RS06010	COG4106	trans-aconitate 2-methyltransferase activity
SYNCC9902_RS06015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SYNCC9902_RS06080	COG0300	oxidoreductase activity
SYNCC9902_RS06110	COG1357	PFAM Pentapeptide repeats (8 copies)
SYNCC9902_RS06115	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SYNCC9902_RS06125	COG0129	dihydroxy-acid dehydratase activity
SYNCC9902_RS06140	COG0363	glucosamine-6-phosphate deaminase activity
SYNCC9902_RS06145	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SYNCC9902_RS06150	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SYNCC9902_RS06155	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SYNCC9902_RS06160	COG1494	fructose-1,6-bisphosphatase
SYNCC9902_RS06165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SYNCC9902_RS06175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SYNCC9902_RS06200	COG1217	gtp-binding protein TYPA
SYNCC9902_RS06205	COG0826	peptidase U32
SYNCC9902_RS06215	COG0644	oxidoreductase
SYNCC9902_RS06225	COG0751	glycine-tRNA ligase activity
SYNCC9902_RS06230	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SYNCC9902_RS06235	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
SYNCC9902_RS06240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SYNCC9902_RS06250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SYNCC9902_RS06255	COG0052	Belongs to the universal ribosomal protein uS2 family
SYNCC9902_RS06260	COG1216	Glycosyl transferase, family 2
SYNCC9902_RS06285	COG0612	Peptidase, M16
SYNCC9902_RS06305	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SYNCC9902_RS06310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SYNCC9902_RS06330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SYNCC9902_RS06340	COG0174	glutamine synthetase
SYNCC9902_RS06345	COG2226	methyltransferase
SYNCC9902_RS06370	COG0515	serine threonine protein kinase
SYNCC9902_RS06375	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
SYNCC9902_RS06380	COG3310	Protein conserved in bacteria
SYNCC9902_RS06405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SYNCC9902_RS06410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SYNCC9902_RS06415	COG0022	dehydrogenase e1 component
SYNCC9902_RS06415	COG0508	dehydrogenase complex catalyzes the overall conversion of
SYNCC9902_RS06425	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SYNCC9902_RS06430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SYNCC9902_RS06435	COG0792	nuclease activity
SYNCC9902_RS06440	COG1357	PFAM Pentapeptide repeats (8 copies)
SYNCC9902_RS06450	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SYNCC9902_RS06490	COG0358	DNA primase activity
SYNCC9902_RS06505	COG0632	four-way junction helicase activity
SYNCC9902_RS06510	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SYNCC9902_RS06520	COG0587	DNA-directed DNA polymerase activity
SYNCC9902_RS06525	COG0154	amidase activity
SYNCC9902_RS06535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SYNCC9902_RS06545	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SYNCC9902_RS06555	COG0505	Belongs to the CarA family
SYNCC9902_RS06560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SYNCC9902_RS06565	COG1132	(ABC) transporter
SYNCC9902_RS06575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SYNCC9902_RS06590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SYNCC9902_RS06600	COG2176	DNA-directed DNA polymerase activity
SYNCC9902_RS06605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SYNCC9902_RS06615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SYNCC9902_RS06620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SYNCC9902_RS06625	COG0142	geranyltranstransferase activity
SYNCC9902_RS06630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SYNCC9902_RS06635	COG0860	N-Acetylmuramoyl-L-alanine amidase
SYNCC9902_RS06645	COG2045	Belongs to the ComB family
SYNCC9902_RS06650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SYNCC9902_RS06655	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SYNCC9902_RS06665	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SYNCC9902_RS06670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SYNCC9902_RS06680	COG0297	glycogen (starch) synthase activity
SYNCC9902_RS06685	COG1376	ErfK ybiS ycfS ynhG family protein
SYNCC9902_RS06690	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SYNCC9902_RS06695	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SYNCC9902_RS06700	COG0681	Belongs to the peptidase S26 family
SYNCC9902_RS06730	COG2890	protein-(glutamine-N5) methyltransferase activity
SYNCC9902_RS06780	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SYNCC9902_RS06785	COG0300	oxidoreductase activity
SYNCC9902_RS06805	COG2154	pterin-4-alpha-carbinolamine dehydratase
SYNCC9902_RS06820	COG0701	Predicted permease
SYNCC9902_RS06850	COG1121	(ABC) transporter
SYNCC9902_RS06855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SYNCC9902_RS06880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SYNCC9902_RS06900	COG1640	4-alpha-glucanotransferase
SYNCC9902_RS06910	COG1187	pseudouridine synthase activity
SYNCC9902_RS06920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SYNCC9902_RS06925	COG1982	Orn Lys Arg decarboxylase major
SYNCC9902_RS06930	COG3220	belongs to the UPF0276 family
SYNCC9902_RS06945	COG2132	Multicopper oxidase
SYNCC9902_RS06950	COG0575	Belongs to the CDS family
SYNCC9902_RS06960	COG0596	Alpha beta hydrolase
SYNCC9902_RS06960	COG0508	dehydrogenase complex catalyzes the overall conversion of
SYNCC9902_RS06965	COG0371	Dehydrogenase
SYNCC9902_RS06970	COG0542	response to heat
SYNCC9902_RS06980	COG0019	diaminopimelate decarboxylase activity
SYNCC9902_RS06985	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SYNCC9902_RS06990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SYNCC9902_RS06995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SYNCC9902_RS07000	COG1054	Belongs to the UPF0176 family
SYNCC9902_RS07015	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SYNCC9902_RS07020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SYNCC9902_RS07030	COG0475	glutathione-regulated potassium exporter activity
SYNCC9902_RS07030	COG0589	response to stress
SYNCC9902_RS07035	COG1132	(ABC) transporter
SYNCC9902_RS07045	COG0724	RNA recognition motif
SYNCC9902_RS07060	COG0513	Belongs to the DEAD box helicase family
SYNCC9902_RS07070	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SYNCC9902_RS07075	COG1074	ATP-dependent DNA helicase activity
SYNCC9902_RS07080	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
SYNCC9902_RS07095	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
SYNCC9902_RS07110	COG0271	Belongs to the BolA IbaG family
SYNCC9902_RS07115	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
SYNCC9902_RS07125	COG0745	RESPONSE REGULATOR receiver
SYNCC9902_RS07150	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SYNCC9902_RS07355	COG0123	including yeast histone deacetylase and acetoin utilization protein
SYNCC9902_RS07455	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SYNCC9902_RS07460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SYNCC9902_RS07465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYNCC9902_RS07470	COG2135	peptidase activity
SYNCC9902_RS07480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SYNCC9902_RS07480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SYNCC9902_RS07520	COG0745	RESPONSE REGULATOR receiver
SYNCC9902_RS07525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SYNCC9902_RS07540	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SYNCC9902_RS07545	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
SYNCC9902_RS07555	COG0196	riboflavin kinase activity
SYNCC9902_RS07565	COG0352	thiamine-phosphate diphosphorylase activity
SYNCC9902_RS07580	COG1691	(AIR) carboxylase
SYNCC9902_RS07590	COG0336	Belongs to the RNA methyltransferase TrmD family
SYNCC9902_RS07605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SYNCC9902_RS07620	COG0670	Belongs to the BI1 family
SYNCC9902_RS07625	COG1702	phosphate starvation-inducible protein PhoH
SYNCC9902_RS07630	COG0228	four-way junction DNA binding
SYNCC9902_RS07635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SYNCC9902_RS07645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SYNCC9902_RS07650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYNCC9902_RS07665	COG0482	sulfurtransferase activity
SYNCC9902_RS07670	COG0815	Transfers the fatty acyl group on membrane lipoproteins
SYNCC9902_RS07705	COG0134	indole-3-glycerol-phosphate synthase activity
SYNCC9902_RS07710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SYNCC9902_RS07715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SYNCC9902_RS07730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SYNCC9902_RS07740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SYNCC9902_RS07745	COG0285	dihydrofolate synthase activity
SYNCC9902_RS07750	COG1357	PFAM Pentapeptide repeats (8 copies)
SYNCC9902_RS07775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SYNCC9902_RS07780	COG1181	Belongs to the D-alanine--D-alanine ligase family
SYNCC9902_RS07795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SYNCC9902_RS07800	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SYNCC9902_RS07805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SYNCC9902_RS07810	COG4956	integral membrane protein (PIN domain superfamily)
SYNCC9902_RS07815	COG0740	serine-type endopeptidase activity
SYNCC9902_RS07820	COG0740	serine-type endopeptidase activity
SYNCC9902_RS07825	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SYNCC9902_RS07830	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
SYNCC9902_RS07890	COG0752	glycyl-tRNA synthetase alpha subunit
SYNCC9902_RS07930	COG2226	methyltransferase
SYNCC9902_RS07935	COG0107	imidazoleglycerol-phosphate synthase activity
SYNCC9902_RS07945	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SYNCC9902_RS07955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SYNCC9902_RS07955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SYNCC9902_RS07960	COG3695	enzyme binding
SYNCC9902_RS07965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SYNCC9902_RS07980	COG5002	protein histidine kinase activity
SYNCC9902_RS07990	COG0481	GTPase activity
SYNCC9902_RS08000	COG0579	oxidoreductase
SYNCC9902_RS08005	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SYNCC9902_RS08010	COG1104	cysteine desulfurase activity
SYNCC9902_RS08015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SYNCC9902_RS08025	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SYNCC9902_RS08030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SYNCC9902_RS08055	COG0424	maF-like protein
SYNCC9902_RS08065	COG1492	cobalamin metabolic process
SYNCC9902_RS08085	COG2197	response regulator
SYNCC9902_RS08115	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
SYNCC9902_RS08120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SYNCC9902_RS08125	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SYNCC9902_RS08150	COG4451	ribulose bisphosphate carboxylase, small
SYNCC9902_RS08155	COG1850	ribulose-bisphosphate carboxylase activity
SYNCC9902_RS08160	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SYNCC9902_RS08165	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SYNCC9902_RS08170	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
SYNCC9902_RS08180	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SYNCC9902_RS08185	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
SYNCC9902_RS08190	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
SYNCC9902_RS08220	COG0730	response to heat
SYNCC9902_RS08230	COG1994	Peptidase M50
SYNCC9902_RS08230	COG0517	IMP dehydrogenase activity
SYNCC9902_RS08235	COG0135	phosphoribosylanthranilate isomerase activity
SYNCC9902_RS08240	COG0302	gtp cyclohydrolase
SYNCC9902_RS08250	COG0825	malonyl-CoA metabolic process
SYNCC9902_RS08255	COG5322	oxidoreductase activity
SYNCC9902_RS08260	COG3396	Phenylacetate-CoA oxygenase
SYNCC9902_RS08270	COG0539	negative regulation of cytoplasmic translation
SYNCC9902_RS08285	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
SYNCC9902_RS08300	COG0028	Belongs to the TPP enzyme family
SYNCC9902_RS08305	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SYNCC9902_RS08315	COG2226	methyltransferase
SYNCC9902_RS08330	COG0528	UMP kinase activity
SYNCC9902_RS08335	COG0233	cytoplasmic translational termination
SYNCC9902_RS08345	COG0415	Belongs to the DNA photolyase family
SYNCC9902_RS08350	COG2814	Major facilitator Superfamily
SYNCC9902_RS08355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SYNCC9902_RS08360	COG0768	penicillin binding
SYNCC9902_RS08375	COG0588	phosphoglycerate mutase activity
SYNCC9902_RS08405	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SYNCC9902_RS08420	COG0442	prolyl-tRNA aminoacylation
SYNCC9902_RS08430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SYNCC9902_RS08435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SYNCC9902_RS08440	COG1324	tolerance protein
SYNCC9902_RS08465	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SYNCC9902_RS08475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SYNCC9902_RS08480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYNCC9902_RS08490	COG0181	hydroxymethylbilane synthase activity
SYNCC9902_RS08510	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
SYNCC9902_RS08515	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SYNCC9902_RS08530	COG0432	Pfam Uncharacterised protein family UPF0047
SYNCC9902_RS08535	COG2154	pterin-4-alpha-carbinolamine dehydratase
SYNCC9902_RS08540	COG0523	cobalamin synthesis protein
SYNCC9902_RS08555	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
SYNCC9902_RS08560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYNCC9902_RS08580	COG0708	Exodeoxyribonuclease III
SYNCC9902_RS08585	COG0277	FAD linked oxidase domain protein
SYNCC9902_RS08590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SYNCC9902_RS08625	COG1666	GTP binding
SYNCC9902_RS08640	COG0857	belongs to the CobB CobQ family
SYNCC9902_RS08650	COG0300	oxidoreductase activity
SYNCC9902_RS08650	COG3000	fatty acid hydroxylase
SYNCC9902_RS08655	COG0024	Methionine aminopeptidase
SYNCC9902_RS08665	COG0335	large ribosomal subunit rRNA binding
SYNCC9902_RS08685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SYNCC9902_RS08705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SYNCC9902_RS08715	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SYNCC9902_RS08720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SYNCC9902_RS08735	COG0194	GDP metabolic process
SYNCC9902_RS08740	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SYNCC9902_RS08745	COG0805	protein transport
SYNCC9902_RS08755	COG0723	plastoquinol--plastocyanin reductase activity
SYNCC9902_RS08760	COG0739	heme binding
SYNCC9902_RS08765	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SYNCC9902_RS08770	COG2875	Belongs to the precorrin methyltransferase family
SYNCC9902_RS08785	COG0248	Ppx GppA phosphatase
SYNCC9902_RS08790	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
SYNCC9902_RS08795	COG1619	proteins homologs of microcin C7 resistance protein MccF
SYNCC9902_RS08800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SYNCC9902_RS08815	COG1028	Short-chain dehydrogenase reductase Sdr
SYNCC9902_RS08825	COG0459	protein refolding
SYNCC9902_RS08830	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SYNCC9902_RS08850	COG0109	protoheme IX farnesyltransferase activity
SYNCC9902_RS08855	COG1612	heme a metabolic process
SYNCC9902_RS08870	COG1845	cytochrome c oxidase, subunit III
SYNCC9902_RS08900	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
SYNCC9902_RS08915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SYNCC9902_RS08920	COG1007	ATP synthesis coupled electron transport
SYNCC9902_RS08925	COG1136	(ABC) transporter
SYNCC9902_RS08925	COG0577	efflux transmembrane transporter activity
SYNCC9902_RS08935	COG5002	protein histidine kinase activity
SYNCC9902_RS08945	COG0745	RESPONSE REGULATOR receiver
SYNCC9902_RS08950	COG0739	heme binding
SYNCC9902_RS08955	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SYNCC9902_RS08955	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SYNCC9902_RS08960	COG0436	Aminotransferase
SYNCC9902_RS08965	COG3118	belongs to the thioredoxin family
SYNCC9902_RS08970	COG1842	Phage shock protein A
SYNCC9902_RS08980	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SYNCC9902_RS08990	COG0697	spore germination
SYNCC9902_RS08995	COG0616	signal peptide processing
SYNCC9902_RS09010	COG0594	ribonuclease P activity
SYNCC9902_RS09020	COG0706	membrane insertase activity
SYNCC9902_RS09030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYNCC9902_RS09035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SYNCC9902_RS09040	COG0750	zinc metalloprotease
SYNCC9902_RS09045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SYNCC9902_RS09050	COG1185	polyribonucleotide nucleotidyltransferase activity
SYNCC9902_RS09060	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SYNCC9902_RS09140	COG0401	homolog of Blt101
SYNCC9902_RS09155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SYNCC9902_RS09175	COG2988	succinylglutamate desuccinylase activity
SYNCC9902_RS09180	COG0435	Glutathione S-transferase
SYNCC9902_RS09190	COG0488	(ABC) transporter
SYNCC9902_RS09200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SYNCC9902_RS09205	COG3842	ATPase activity
SYNCC9902_RS09210	COG1193	negative regulation of DNA recombination
SYNCC9902_RS09220	COG0113	porphobilinogen synthase activity
SYNCC9902_RS09225	COG0484	heat shock protein binding
SYNCC9902_RS09235	COG0659	secondary active sulfate transmembrane transporter activity
SYNCC9902_RS09245	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SYNCC9902_RS09265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SYNCC9902_RS09270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SYNCC9902_RS09275	COG0366	Alpha amylase catalytic
SYNCC9902_RS09280	COG1012	belongs to the aldehyde dehydrogenase family
SYNCC9902_RS09290	COG0514	ATP-dependent DNA helicase (RecQ)
SYNCC9902_RS09305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SYNCC9902_RS09310	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SYNCC9902_RS09315	COG0235	Class ii aldolase
SYNCC9902_RS09320	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
SYNCC9902_RS09355	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SYNCC9902_RS09360	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SYNCC9902_RS09365	COG0793	Belongs to the peptidase S41A family
SYNCC9902_RS09370	COG1078	dGTPase activity
SYNCC9902_RS09375	COG0850	regulation of cytokinetic process
SYNCC9902_RS09380	COG2894	cell division
SYNCC9902_RS09385	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
SYNCC9902_RS09400	COG0009	L-threonylcarbamoyladenylate synthase
SYNCC9902_RS09405	COG2890	protein-(glutamine-N5) methyltransferase activity
SYNCC9902_RS09410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SYNCC9902_RS09410	COG0758	DNA mediated transformation
SYNCC9902_RS09415	COG0824	Thioesterase
SYNCC9902_RS09420	COG0589	response to stress
SYNCC9902_RS09445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SYNCC9902_RS09450	COG0539	negative regulation of cytoplasmic translation
SYNCC9902_RS09460	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SYNCC9902_RS09465	COG1070	Carbohydrate kinase
SYNCC9902_RS09480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SYNCC9902_RS09525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SYNCC9902_RS09670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SYNCC9902_RS09675	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SYNCC9902_RS09675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SYNCC9902_RS09680	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SYNCC9902_RS09685	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SYNCC9902_RS09720	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
SYNCC9902_RS09740	COG0408	coproporphyrinogen oxidase activity
SYNCC9902_RS09745	COG0489	protein tyrosine kinase activity
SYNCC9902_RS09750	COG0772	Belongs to the SEDS family
SYNCC9902_RS09765	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SYNCC9902_RS09770	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
SYNCC9902_RS09775	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SYNCC9902_RS09790	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SYNCC9902_RS09795	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SYNCC9902_RS09800	COG1606	tRNA processing
SYNCC9902_RS09805	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
SYNCC9902_RS09830	COG3001	Fructosamine kinase
SYNCC9902_RS09860	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
SYNCC9902_RS09875	COG3854	ATPases associated with a variety of cellular activities
SYNCC9902_RS09890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SYNCC9902_RS09895	COG0088	Forms part of the polypeptide exit tunnel
SYNCC9902_RS09900	COG0089	rRNA binding
SYNCC9902_RS09905	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
SYNCC9902_RS09910	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SYNCC9902_RS09915	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SYNCC9902_RS09920	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SYNCC9902_RS09925	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SYNCC9902_RS09930	COG0255	Belongs to the universal ribosomal protein uL29 family
SYNCC9902_RS09935	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SYNCC9902_RS09940	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SYNCC9902_RS09945	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SYNCC9902_RS09950	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SYNCC9902_RS09955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SYNCC9902_RS09960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SYNCC9902_RS09965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SYNCC9902_RS09970	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SYNCC9902_RS09975	COG0200	Binds to the 23S rRNA
SYNCC9902_RS09980	COG0201	protein transport
SYNCC9902_RS09985	COG0563	adenylate kinase activity
SYNCC9902_RS09990	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SYNCC9902_RS09995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SYNCC9902_RS10000	COG0202	RNA polymerase activity
SYNCC9902_RS10005	COG0203	ribosomal protein L17
SYNCC9902_RS10010	COG0101	tRNA pseudouridine synthase activity
SYNCC9902_RS10015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SYNCC9902_RS10020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SYNCC9902_RS10025	COG0254	rRNA binding
SYNCC9902_RS10030	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SYNCC9902_RS10040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SYNCC9902_RS10060	COG0463	Glycosyl transferase, family 2
SYNCC9902_RS10085	COG2885	chlorophyll binding
SYNCC9902_RS10090	COG2885	chlorophyll binding
SYNCC9902_RS10110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SYNCC9902_RS10115	COG3659	wide pore channel activity
SYNCC9902_RS10125	COG3128	pkhd-type hydroxylase
SYNCC9902_RS10130	COG1840	ABC-type Fe3 transport system, periplasmic component
SYNCC9902_RS10150	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SYNCC9902_RS10160	COG0716	FMN binding
SYNCC9902_RS10185	COG3659	wide pore channel activity
SYNCC9902_RS10200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
SYNCC9902_RS10210	COG0070	glutamate synthase
SYNCC9902_RS10210	COG0069	glutamate synthase activity
SYNCC9902_RS10210	COG0067	glutamate synthase
SYNCC9902_RS10225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SYNCC9902_RS10230	COG0049	tRNA binding
SYNCC9902_RS10235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SYNCC9902_RS10240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SYNCC9902_RS10245	COG0051	transcription antitermination factor activity, RNA binding
SYNCC9902_RS10250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SYNCC9902_RS10255	COG2226	methyltransferase
SYNCC9902_RS10260	COG1605	Chorismate mutase
SYNCC9902_RS10260	COG0077	Prephenate dehydratase
SYNCC9902_RS10270	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SYNCC9902_RS10275	COG1530	ribonuclease E activity
SYNCC9902_RS10285	COG0436	Aminotransferase
SYNCC9902_RS10290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
SYNCC9902_RS10305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SYNCC9902_RS10330	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SYNCC9902_RS10340	COG0800	Aldolase
SYNCC9902_RS10345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SYNCC9902_RS10350	COG0529	Catalyzes the synthesis of activated sulfate
SYNCC9902_RS10350	COG2046	Belongs to the sulfate adenylyltransferase family
SYNCC9902_RS10360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SYNCC9902_RS10390	COG0540	Belongs to the ATCase OTCase family
SYNCC9902_RS10395	COG2094	Belongs to the DNA glycosylase MPG family
SYNCC9902_RS10400	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SYNCC9902_RS10415	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SYNCC9902_RS10435	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SYNCC9902_RS10455	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SYNCC9902_RS10465	COG2971	BadF BadG BcrA BcrD
SYNCC9902_RS10470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SYNCC9902_RS10480	COG1196	nuclear chromosome segregation
SYNCC9902_RS10480	COG0741	lytic transglycosylase activity
SYNCC9902_RS10480	COG0739	heme binding
SYNCC9902_RS10485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SYNCC9902_RS10495	COG0717	Belongs to the dCTP deaminase family
SYNCC9902_RS10505	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SYNCC9902_RS10510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SYNCC9902_RS10515	COG4372	Transposase
SYNCC9902_RS10530	COG0193	aminoacyl-tRNA hydrolase activity
SYNCC9902_RS10535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SYNCC9902_RS10570	COG0066	3-isopropylmalate dehydratase activity
SYNCC9902_RS10575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SYNCC9902_RS10580	COG1058	Belongs to the CinA family
SYNCC9902_RS10580	COG1546	Belongs to the CinA family
SYNCC9902_RS10585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SYNCC9902_RS10590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SYNCC9902_RS10625	COG1420	regulation of RNA biosynthetic process
SYNCC9902_RS10630	COG0133	tryptophan synthase activity
SYNCC9902_RS10635	COG0023	Translation Initiation Factor
SYNCC9902_RS10640	COG0529	Catalyzes the synthesis of activated sulfate
SYNCC9902_RS10645	COG0628	permease
SYNCC9902_RS10655	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SYNCC9902_RS10665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SYNCC9902_RS10670	COG0564	pseudouridine synthase activity
SYNCC9902_RS10675	COG0745	RESPONSE REGULATOR receiver
SYNCC9902_RS10685	COG1104	cysteine desulfurase activity
SYNCC9902_RS10695	COG0275	rRNA processing
SYNCC9902_RS10700	COG0649	NAD binding
SYNCC9902_RS10720	COG0824	Thioesterase
SYNCC9902_RS10735	COG1575	Belongs to the MenA family. Type 1 subfamily
SYNCC9902_RS10745	COG0189	ligase activity
SYNCC9902_RS10750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SYNCC9902_RS10755	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SYNCC9902_RS10760	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SYNCC9902_RS10765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SYNCC9902_RS10770	COG0512	Glutamine amidotransferase of anthranilate synthase
SYNCC9902_RS10790	COG0252	asparaginase activity
SYNCC9902_RS10795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SYNCC9902_RS10800	COG0018	arginyl-trna synthetase
SYNCC9902_RS10805	COG0157	Belongs to the NadC ModD family
SYNCC9902_RS10810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SYNCC9902_RS10820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
SYNCC9902_RS10825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SYNCC9902_RS10830	COG4172	Belongs to the ABC transporter superfamily
SYNCC9902_RS10835	COG0564	pseudouridine synthase activity
SYNCC9902_RS10845	COG0126	phosphoglycerate kinase activity
SYNCC9902_RS10865	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SYNCC9902_RS10870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SYNCC9902_RS10880	COG0167	dihydroorotate dehydrogenase activity
SYNCC9902_RS10885	COG0328	RNA-DNA hybrid ribonuclease activity
SYNCC9902_RS10900	COG0222	ribosome binding
SYNCC9902_RS10905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SYNCC9902_RS10910	COG0081	regulation of translation
SYNCC9902_RS10915	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SYNCC9902_RS10920	COG0250	Participates in transcription elongation, termination and antitermination
SYNCC9902_RS10925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SYNCC9902_RS10930	COG0542	response to heat
SYNCC9902_RS10935	COG0346	lactoylglutathione lyase activity
SYNCC9902_RS10940	COG0148	phosphopyruvate hydratase activity
SYNCC9902_RS10945	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SYNCC9902_RS10975	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SYNCC9902_RS10980	COG0237	dephospho-CoA kinase activity
SYNCC9902_RS10990	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SYNCC9902_RS10995	COG2022	thiamine diphosphate biosynthetic process
SYNCC9902_RS10995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SYNCC9902_RS11000	COG0105	UTP biosynthetic process
SYNCC9902_RS11005	COG1166	arginine decarboxylase activity
SYNCC9902_RS11010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SYNCC9902_RS11020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SYNCC9902_RS11045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SYNCC9902_RS11045	COG0426	domain, Protein
SYNCC9902_RS11065	COG0426	domain, Protein
SYNCC9902_RS11065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SYNCC9902_RS11070	COG1773	rubredoxin
SYNCC9902_RS11090	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SYNCC9902_RS11090	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SYNCC9902_RS11095	COG0509	glycine decarboxylation via glycine cleavage system
SYNCC9902_RS11100	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SYNCC9902_RS11115	COG0359	binds to the 23S rRNA
SYNCC9902_RS11120	COG1372	Participates in initiation and elongation during chromosome replication
SYNCC9902_RS11120	COG0305	Participates in initiation and elongation during chromosome replication
SYNCC9902_RS11120	COG1372	Participates in initiation and elongation during chromosome replication
SYNCC9902_RS11120	COG0305	Participates in initiation and elongation during chromosome replication
SYNCC9902_RS11135	COG0445	tRNA wobble uridine modification
SYNCC9902_RS11175	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SYNCC9902_RS11190	COG0398	Pfam SNARE associated Golgi protein
SYNCC9902_RS11210	COG0668	transmembrane transport
SYNCC9902_RS11215	COG0525	valine-tRNA ligase activity
SYNCC9902_RS11245	COG4221	oxidoreductase activity
SYNCC9902_RS11295	COG3956	TIGRFAM MazG family protein
SYNCC9902_RS11310	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SYNCC9902_RS11315	COG0010	Belongs to the arginase family
SYNCC9902_RS11325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SYNCC9902_RS11330	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SYNCC9902_RS11335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYNCC9902_RS11340	COG0504	CTP synthase activity
SYNCC9902_RS11345	COG0602	queuosine metabolic process
SYNCC9902_RS11355	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SYNCC9902_RS11370	COG0531	amino acid
SYNCC9902_RS11380	COG0366	Alpha amylase catalytic
SYNCC9902_RS11415	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SYNCC9902_RS11420	COG0830	nickel cation binding
SYNCC9902_RS11425	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SYNCC9902_RS11430	COG0829	nickel cation binding
SYNCC9902_RS11435	COG0831	urea catabolic process
SYNCC9902_RS11440	COG0832	Belongs to the urease beta subunit family
SYNCC9902_RS11445	COG0804	urea catabolic process
SYNCC9902_RS11460	COG0367	asparagine synthase
SYNCC9902_RS11465	COG0540	Belongs to the ATCase OTCase family
SYNCC9902_RS11470	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SYNCC9902_RS11475	COG2308	Evidence 4 Homologs of previously reported genes of
SYNCC9902_RS11500	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SYNCC9902_RS11510	COG2223	nitrite transmembrane transporter activity
SYNCC9902_RS11515	COG0243	molybdopterin cofactor binding
SYNCC9902_RS11535	COG0315	cyclic pyranopterin monophosphate synthase activity
SYNCC9902_RS11545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SYNCC9902_RS11550	COG0314	molybdopterin synthase activity
SYNCC9902_RS11560	COG0521	Mo-molybdopterin cofactor biosynthetic process
SYNCC9902_RS11565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SYNCC9902_RS11575	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SYNCC9902_RS11580	COG2116	formate transmembrane transporter activity
SYNCC9902_RS11590	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
SYNCC9902_RS11600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SYNCC9902_RS11615	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
SYNCC9902_RS11620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SYNCC9902_RS11625	COG0170	dolichyl monophosphate biosynthetic process
SYNCC9902_RS11630	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SYNCC9902_RS11635	COG1049	propionate catabolic process, 2-methylcitrate cycle
SYNCC9902_RS11640	COG0038	chloride channel
SYNCC9902_RS11645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SYNCC9902_RS11655	COG0788	formyltetrahydrofolate deformylase activity
SYNCC9902_RS11670	COG0443	Heat shock 70 kDa protein
SYNCC9902_RS11675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SYNCC9902_RS11685	COG0360	Binds together with S18 to 16S ribosomal RNA
SYNCC9902_RS11695	COG0137	argininosuccinate synthase activity
SYNCC9902_RS11710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SYNCC9902_RS11720	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
SYNCC9902_RS11725	COG0438	transferase activity, transferring glycosyl groups
SYNCC9902_RS11735	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SYNCC9902_RS11740	COG0497	DNA recombination
SYNCC9902_RS11745	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
SYNCC9902_RS11755	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SYNCC9902_RS11770	COG0724	RNA recognition motif