locus-tag	class	description
CYB_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CYB_RS00020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CYB_RS00025	COG0300	oxidoreductase activity
CYB_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CYB_RS00045	COG0488	(ABC) transporter
CYB_RS00060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CYB_RS00090	COG2885	chlorophyll binding
CYB_RS00095	COG2885	chlorophyll binding
CYB_RS00100	COG0804	urea catabolic process
CYB_RS00105	COG3842	ATPase activity
CYB_RS00115	COG4134	Bacterial extracellular solute-binding protein
CYB_RS00120	COG5002	protein histidine kinase activity
CYB_RS00150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CYB_RS00155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYB_RS00160	COG1116	anion transmembrane transporter activity
CYB_RS00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CYB_RS00165	COG1116	anion transmembrane transporter activity
CYB_RS00175	COG0243	molybdopterin cofactor binding
CYB_RS00190	COG0151	Belongs to the GarS family
CYB_RS00200	COG1078	dGTPase activity
CYB_RS00210	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CYB_RS00215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CYB_RS00220	COG0778	Nitroreductase
CYB_RS00225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CYB_RS00230	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CYB_RS00240	COG3293	Transposase
CYB_RS00250	COG2052	Domain of unknown function (DUF370)
CYB_RS00255	COG0194	GDP metabolic process
CYB_RS00260	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CYB_RS00265	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CYB_RS00275	COG0123	including yeast histone deacetylase and acetoin utilization protein
CYB_RS00285	COG0799	negative regulation of ribosome biogenesis
CYB_RS00295	COG0481	GTPase activity
CYB_RS00305	COG0752	glycyl-tRNA synthetase alpha subunit
CYB_RS00315	COG1160	GTP binding
CYB_RS00330	COG0436	Aminotransferase
CYB_RS00340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CYB_RS00365	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CYB_RS00380	COG0544	peptidyl-prolyl cis-trans isomerase activity
CYB_RS00390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CYB_RS00410	COG1570	exodeoxyribonuclease VII activity
CYB_RS00415	COG1722	exodeoxyribonuclease VII activity
CYB_RS00420	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CYB_RS00445	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CYB_RS00450	COG0741	lytic transglycosylase activity
CYB_RS00450	COG1196	nuclear chromosome segregation
CYB_RS00450	COG0739	heme binding
CYB_RS00455	COG2062	phosphohistidine phosphatase, SixA
CYB_RS00465	COG0484	heat shock protein binding
CYB_RS00505	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CYB_RS00530	COG0450	alkyl hydroperoxide reductase
CYB_RS00540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CYB_RS00550	COG0629	single-stranded DNA binding
CYB_RS00555	COG2099	Precorrin-6x reductase
CYB_RS00570	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CYB_RS00585	COG0748	coenzyme F420 binding
CYB_RS00590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CYB_RS00595	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CYB_RS00595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CYB_RS00615	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CYB_RS00625	COG1178	ABC-type Fe3 transport system permease component
CYB_RS00645	COG1555	photosystem II stabilization
CYB_RS00650	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CYB_RS00650	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CYB_RS00670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CYB_RS00675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CYB_RS00680	COG2166	iron-sulfur cluster assembly
CYB_RS00685	COG3443	Belongs to the bacterial solute-binding protein 9 family
CYB_RS00685	COG0803	Belongs to the bacterial solute-binding protein 9 family
CYB_RS00690	COG1121	(ABC) transporter
CYB_RS00695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CYB_RS00705	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CYB_RS00710	COG0484	heat shock protein binding
CYB_RS00720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CYB_RS00735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CYB_RS00750	COG0140	phosphoribosyl-ATP diphosphatase activity
CYB_RS00750	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CYB_RS00755	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CYB_RS00765	COG3639	organic phosphonate transmembrane transporter activity
CYB_RS00785	COG3627	carbon phosphorus lyase activity
CYB_RS00790	COG4107	phosphonate C-P lyase system protein PhnK
CYB_RS00795	COG4778	phosphonate C-P lyase system protein PhnL
CYB_RS00800	COG3454	Phosphonate metabolism
CYB_RS00805	COG1649	PFAM Uncharacterised BCR, COG1649
CYB_RS00805	COG0726	polysaccharide deacetylase
CYB_RS00825	COG0745	RESPONSE REGULATOR receiver
CYB_RS00855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CYB_RS00860	COG4178	(ABC) transporter
CYB_RS00865	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CYB_RS00875	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CYB_RS00895	COG0302	gtp cyclohydrolase
CYB_RS00900	COG0300	oxidoreductase activity
CYB_RS00905	COG3842	ATPase activity
CYB_RS00915	COG3118	belongs to the thioredoxin family
CYB_RS00925	COG0135	phosphoribosylanthranilate isomerase activity
CYB_RS00935	COG1187	pseudouridine synthase activity
CYB_RS00940	COG3293	Transposase
CYB_RS00955	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CYB_RS00965	COG0415	Belongs to the DNA photolyase family
CYB_RS00975	COG3293	Transposase
CYB_RS00985	COG0303	'Molybdopterin
CYB_RS00995	COG1007	ATP synthesis coupled electron transport
CYB_RS01030	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CYB_RS01040	COG0527	aspartate kinase activity
CYB_RS01060	COG0163	prenyltransferase activity
CYB_RS01070	COG2082	Precorrin-8x methylmutase
CYB_RS01090	COG1489	DNA binding
CYB_RS01095	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CYB_RS01100	COG0708	Exodeoxyribonuclease III
CYB_RS01115	COG1176	ABC-type spermidine putrescine transport system, permease component I
CYB_RS01120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CYB_RS01125	COG4208	sulfate ABC transporter
CYB_RS01130	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CYB_RS01135	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CYB_RS01140	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CYB_RS01150	COG1012	belongs to the aldehyde dehydrogenase family
CYB_RS01150	COG1454	alcohol dehydrogenase
CYB_RS01160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CYB_RS01170	COG1882	Formate acetyltransferase
CYB_RS01175	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CYB_RS01180	COG0675	Transposase, IS605 OrfB family
CYB_RS01190	COG0745	RESPONSE REGULATOR receiver
CYB_RS01195	COG1834	amidinotransferase
CYB_RS01220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CYB_RS01225	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CYB_RS01230	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CYB_RS01235	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CYB_RS01255	COG1116	anion transmembrane transporter activity
CYB_RS01265	COG0105	UTP biosynthetic process
CYB_RS01285	COG0737	Belongs to the 5'-nucleotidase family
CYB_RS01295	COG0515	serine threonine protein kinase
CYB_RS01305	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CYB_RS01315	COG0633	Ferredoxin
CYB_RS01330	COG0784	Response regulator, receiver
CYB_RS01335	COG0047	phosphoribosylformylglycinamidine synthase activity
CYB_RS01340	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CYB_RS01350	COG2045	Belongs to the ComB family
CYB_RS01360	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CYB_RS01370	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CYB_RS01375	COG0772	Belongs to the SEDS family
CYB_RS01395	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYB_RS01400	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CYB_RS01405	COG0575	Belongs to the CDS family
CYB_RS01415	COG0525	valine-tRNA ligase activity
CYB_RS01420	COG0724	RNA recognition motif
CYB_RS01440	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CYB_RS01445	COG4603	Belongs to the binding-protein-dependent transport system permease family
CYB_RS01450	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CYB_RS01460	COG0552	protein localization to endoplasmic reticulum
CYB_RS01485	COG0850	regulation of cytokinetic process
CYB_RS01490	COG2894	cell division
CYB_RS01495	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CYB_RS01510	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CYB_RS01515	COG0187	DNA topoisomerase II activity
CYB_RS01515	COG1372	Participates in initiation and elongation during chromosome replication
CYB_RS01520	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CYB_RS01525	COG0330	HflC and HflK could
CYB_RS01540	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CYB_RS01560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CYB_RS01565	COG0583	DNA-binding transcription factor activity
CYB_RS01570	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CYB_RS01600	COG0371	Dehydrogenase
CYB_RS01615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CYB_RS01630	COG0284	orotidine-5'-phosphate decarboxylase activity
CYB_RS01640	COG1496	oxidoreductase activity
CYB_RS01655	COG0509	glycine decarboxylation via glycine cleavage system
CYB_RS01660	COG0596	Alpha beta hydrolase
CYB_RS01665	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CYB_RS01670	COG0745	RESPONSE REGULATOR receiver
CYB_RS01675	COG0675	Transposase, IS605 OrfB family
CYB_RS01690	COG0191	fructose-bisphosphate aldolase activity
CYB_RS01700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CYB_RS01705	COG0860	N-Acetylmuramoyl-L-alanine amidase
CYB_RS01725	COG2226	methyltransferase
CYB_RS01760	COG1615	UPF0182 protein
CYB_RS01775	COG0746	molybdenum cofactor guanylyltransferase activity
CYB_RS01790	COG0537	adenosine 5'-monophosphoramidase activity
CYB_RS01805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CYB_RS01805	COG0426	domain, Protein
CYB_RS01810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CYB_RS01830	COG1079	Belongs to the binding-protein-dependent transport system permease family
CYB_RS01835	COG4603	Belongs to the binding-protein-dependent transport system permease family
CYB_RS01840	COG3845	ABC transporter
CYB_RS01850	COG0402	S-adenosylhomocysteine deaminase activity
CYB_RS01860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CYB_RS01885	COG0725	ABC transporter, periplasmic molybdate-binding protein
CYB_RS01890	COG3585	molybdate ion transport
CYB_RS01910	COG0633	Ferredoxin
CYB_RS01920	COG5420	small protein containing a coiled-coil domain
CYB_RS01935	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CYB_RS01940	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CYB_RS01955	COG0783	Belongs to the Dps family
CYB_RS01965	COG1433	Dinitrogenase iron-molybdenum cofactor
CYB_RS01965	COG0535	radical SAM domain protein
CYB_RS01975	COG1104	cysteine desulfurase activity
CYB_RS01985	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CYB_RS01995	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CYB_RS02000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CYB_RS02030	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CYB_RS02030	COG0237	dephospho-CoA kinase activity
CYB_RS02035	COG2255	four-way junction helicase activity
CYB_RS02045	COG1214	PFAM Peptidase M22, glycoprotease
CYB_RS02050	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CYB_RS02055	COG0511	ligase activity, forming carbon-carbon bonds
CYB_RS02065	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CYB_RS02070	COG0175	sulfate reduction
CYB_RS02085	COG0572	uridine kinase
CYB_RS02090	COG1842	Phage shock protein A
CYB_RS02100	COG1218	3'(2'),5'-bisphosphate nucleotidase
CYB_RS02105	COG0107	imidazoleglycerol-phosphate synthase activity
CYB_RS02120	COG0228	four-way junction DNA binding
CYB_RS02130	COG1937	Protein conserved in bacteria
CYB_RS02135	COG0142	geranyltranstransferase activity
CYB_RS02155	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CYB_RS02180	COG0859	PFAM glycosyl transferase family 9
CYB_RS02195	COG1752	Esterase of the alpha-beta hydrolase superfamily
CYB_RS02200	COG0406	alpha-ribazole phosphatase activity
CYB_RS02205	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CYB_RS02210	COG0515	serine threonine protein kinase
CYB_RS02265	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CYB_RS02270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CYB_RS02280	COG1253	flavin adenine dinucleotide binding
CYB_RS02285	COG1982	Orn Lys Arg decarboxylase major
CYB_RS02330	COG1957	nucleoside hydrolase
CYB_RS02335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CYB_RS02340	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CYB_RS02345	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CYB_RS02355	COG1181	Belongs to the D-alanine--D-alanine ligase family
CYB_RS02370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CYB_RS02385	COG0454	-acetyltransferase
CYB_RS02400	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CYB_RS02420	COG0343	queuine tRNA-ribosyltransferase activity
CYB_RS02440	COG0702	epimerase
CYB_RS02445	COG1012	belongs to the aldehyde dehydrogenase family
CYB_RS02455	COG0675	Transposase, IS605 OrfB family
CYB_RS02460	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CYB_RS02470	COG0515	serine threonine protein kinase
CYB_RS02470	COG2815	serine threonine protein kinase
CYB_RS02475	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CYB_RS02480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CYB_RS02490	COG1027	Aspartate ammonia-lyase
CYB_RS02500	COG2211	Major facilitator Superfamily
CYB_RS02525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CYB_RS02535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CYB_RS02550	COG0739	heme binding
CYB_RS02565	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CYB_RS02580	COG1177	transmembrane transport
CYB_RS02585	COG0632	four-way junction helicase activity
CYB_RS02590	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CYB_RS02600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYB_RS02615	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CYB_RS02635	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CYB_RS02640	COG0398	Pfam SNARE associated Golgi protein
CYB_RS02650	COG0251	oxidation-reduction process
CYB_RS02655	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CYB_RS02660	COG2814	Major facilitator Superfamily
CYB_RS02665	COG2385	sporulation resulting in formation of a cellular spore
CYB_RS02685	COG1587	Uroporphyrinogen-III synthase
CYB_RS02695	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CYB_RS02695	COG0237	dephospho-CoA kinase activity
CYB_RS02735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYB_RS02745	COG0517	IMP dehydrogenase activity
CYB_RS02745	COG1125	glycine betaine transport
CYB_RS02765	COG2720	vancomycin resistance protein
CYB_RS02800	COG1337	RAMP superfamily
CYB_RS02840	COG2010	Cytochrome c
CYB_RS02855	COG1116	anion transmembrane transporter activity
CYB_RS02860	COG1116	anion transmembrane transporter activity
CYB_RS02860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CYB_RS02865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYB_RS02870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CYB_RS02885	COG0542	response to heat
CYB_RS02890	COG0740	serine-type endopeptidase activity
CYB_RS02905	COG0740	serine-type endopeptidase activity
CYB_RS02950	COG2010	Cytochrome c
CYB_RS02955	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CYB_RS02970	COG0785	Cytochrome C biogenesis protein
CYB_RS02975	COG1333	cytochrome c biogenesis protein
CYB_RS02995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CYB_RS03005	COG2385	sporulation resulting in formation of a cellular spore
CYB_RS03010	COG0590	tRNA wobble adenosine to inosine editing
CYB_RS03015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYB_RS03035	COG3293	Transposase
CYB_RS03045	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CYB_RS03050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CYB_RS03065	COG0297	glycogen (starch) synthase activity
CYB_RS03070	COG1543	Belongs to the glycosyl hydrolase 57 family
CYB_RS03075	COG0028	Belongs to the TPP enzyme family
CYB_RS03080	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
CYB_RS03085	COG0673	inositol 2-dehydrogenase activity
CYB_RS03090	COG1305	Transglutaminase-like
CYB_RS03095	COG0730	response to heat
CYB_RS03100	COG0077	Prephenate dehydratase
CYB_RS03100	COG1605	Chorismate mutase
CYB_RS03110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CYB_RS03115	COG0616	signal peptide processing
CYB_RS03135	COG0109	protoheme IX farnesyltransferase activity
CYB_RS03145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYB_RS03160	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CYB_RS03165	COG0170	dolichyl monophosphate biosynthetic process
CYB_RS03170	COG2010	Cytochrome c
CYB_RS03180	COG0514	ATP-dependent DNA helicase (RecQ)
CYB_RS03185	COG0131	Imidazoleglycerol-phosphate dehydratase
CYB_RS03195	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
CYB_RS03210	COG0366	Alpha amylase catalytic
CYB_RS03215	COG2135	peptidase activity
CYB_RS03220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CYB_RS03220	COG0758	DNA mediated transformation
CYB_RS03230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CYB_RS03240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CYB_RS03265	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CYB_RS03265	COG0662	Cupin 2, conserved barrel domain protein
CYB_RS03295	COG0124	histidyl-tRNA synthetase
CYB_RS03305	COG2264	protein methyltransferase activity
CYB_RS03320	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CYB_RS03335	COG0438	transferase activity, transferring glycosyl groups
CYB_RS03350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CYB_RS03355	COG0424	maF-like protein
CYB_RS03360	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CYB_RS03365	COG1254	Belongs to the acylphosphatase family
CYB_RS03385	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CYB_RS03385	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CYB_RS03425	COG1716	ATPase activity
CYB_RS03425	COG5001	Diguanylate cyclase
CYB_RS03430	COG0475	glutathione-regulated potassium exporter activity
CYB_RS03435	COG0193	aminoacyl-tRNA hydrolase activity
CYB_RS03460	COG4948	Mandelate Racemase Muconate Lactonizing
CYB_RS03470	COG0612	Peptidase, M16
CYB_RS03475	COG0517	IMP dehydrogenase activity
CYB_RS03475	COG1994	Peptidase M50
CYB_RS03485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CYB_RS03500	COG1136	(ABC) transporter
CYB_RS03505	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CYB_RS03515	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CYB_RS03520	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CYB_RS03535	COG0484	heat shock protein binding
CYB_RS03540	COG4572	Cation transport regulator
CYB_RS03545	COG2234	aminopeptidase activity
CYB_RS03550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CYB_RS03555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CYB_RS03570	COG1194	a g-specific adenine glycosylase
CYB_RS03585	COG0571	ribonuclease III activity
CYB_RS03605	COG2885	chlorophyll binding
CYB_RS03630	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CYB_RS03635	COG0456	acetyltransferase
CYB_RS03645	COG0489	protein tyrosine kinase activity
CYB_RS03655	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CYB_RS03680	COG0497	DNA recombination
CYB_RS03700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CYB_RS03715	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CYB_RS03720	COG0747	negative chemotaxis
CYB_RS03730	COG0438	transferase activity, transferring glycosyl groups
CYB_RS03790	COG1192	Involved in chromosome partitioning
CYB_RS03805	COG1715	Restriction endonuclease
CYB_RS03815	COG0415	Belongs to the DNA photolyase family
CYB_RS03840	COG0556	nucleotide-excision repair
CYB_RS03865	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
CYB_RS03870	COG0675	Transposase, IS605 OrfB family
CYB_RS03880	COG1070	Carbohydrate kinase
CYB_RS03895	COG0811	peptide transport
CYB_RS03900	COG0848	biopolymer transport protein
CYB_RS03905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CYB_RS03910	COG0793	Belongs to the peptidase S41A family
CYB_RS03915	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CYB_RS03925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CYB_RS03925	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CYB_RS03950	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CYB_RS03960	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CYB_RS04030	COG0539	negative regulation of cytoplasmic translation
CYB_RS04035	COG1959	2 iron, 2 sulfur cluster binding
CYB_RS04040	COG0714	Associated with various cellular activities
CYB_RS04045	COG0601	transmembrane transport
CYB_RS04075	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CYB_RS04085	COG5002	protein histidine kinase activity
CYB_RS04115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CYB_RS04130	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYB_RS04135	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CYB_RS04145	COG0649	NAD binding
CYB_RS04155	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CYB_RS04165	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CYB_RS04170	COG0829	nickel cation binding
CYB_RS04190	COG0596	Alpha beta hydrolase
CYB_RS04195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYB_RS04200	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CYB_RS04225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CYB_RS04230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CYB_RS04235	COG1666	GTP binding
CYB_RS04240	COG0300	oxidoreductase activity
CYB_RS04245	COG1716	ATPase activity
CYB_RS04245	COG5001	Diguanylate cyclase
CYB_RS04255	COG0768	penicillin binding
CYB_RS04260	COG0776	regulation of translation
CYB_RS04285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CYB_RS04300	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CYB_RS04305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CYB_RS04325	COG1429	ligase activity, forming nitrogen-metal bonds
CYB_RS04330	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CYB_RS04340	COG0189	ligase activity
CYB_RS04340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CYB_RS04365	COG3437	response regulator, receiver
CYB_RS04370	COG1040	competence protein
CYB_RS04375	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CYB_RS04380	COG0049	tRNA binding
CYB_RS04385	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CYB_RS04390	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CYB_RS04395	COG0051	transcription antitermination factor activity, RNA binding
CYB_RS04400	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CYB_RS04420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CYB_RS04425	COG0746	molybdenum cofactor guanylyltransferase activity
CYB_RS04430	COG0805	protein transport
CYB_RS04435	COG0765	amino acid transport
CYB_RS04440	COG4597	amino acid ABC transporter
CYB_RS04445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYB_RS04450	COG1126	abc transporter atp-binding protein
CYB_RS04470	COG0159	tryptophan synthase activity
CYB_RS04485	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CYB_RS04490	COG1413	lyase activity
CYB_RS04495	COG1413	lyase activity
CYB_RS04500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CYB_RS04505	COG3937	granule-associated protein
CYB_RS04510	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CYB_RS04515	COG0631	protein serine/threonine phosphatase activity
CYB_RS04520	COG0123	including yeast histone deacetylase and acetoin utilization protein
CYB_RS04525	COG0515	serine threonine protein kinase
CYB_RS04570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CYB_RS04610	COG2890	protein-(glutamine-N5) methyltransferase activity
CYB_RS04625	COG0826	peptidase U32
CYB_RS04630	COG0440	acetolactate synthase activity
CYB_RS04645	COG0837	glucose binding
CYB_RS04655	COG2226	methyltransferase
CYB_RS04660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CYB_RS04685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CYB_RS04690	COG0616	signal peptide processing
CYB_RS04695	COG1028	Short-chain dehydrogenase reductase Sdr
CYB_RS04700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CYB_RS04705	COG4999	Histidine kinase
CYB_RS04705	COG2205	protein histidine kinase activity
CYB_RS04705	COG3437	response regulator, receiver
CYB_RS04705	COG3850	Histidine kinase
CYB_RS04710	COG4956	integral membrane protein (PIN domain superfamily)
CYB_RS04715	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CYB_RS04720	COG0750	zinc metalloprotease
CYB_RS04725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CYB_RS04730	COG1660	Displays ATPase and GTPase activities
CYB_RS04735	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CYB_RS04750	COG0768	penicillin binding
CYB_RS04755	COG0463	Glycosyl transferase, family 2
CYB_RS04760	COG1480	7TM receptor with intracellular HD hydrolase
CYB_RS04780	COG1316	TRANSCRIPTIONal
CYB_RS04785	COG0326	Molecular chaperone. Has ATPase activity
CYB_RS04790	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CYB_RS04795	COG0174	glutamine synthetase
CYB_RS04800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CYB_RS04810	COG0745	RESPONSE REGULATOR receiver
CYB_RS04830	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CYB_RS04840	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CYB_RS04850	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CYB_RS04860	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CYB_RS04865	COG0406	alpha-ribazole phosphatase activity
CYB_RS04870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CYB_RS04875	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CYB_RS04895	COG0006	proline dipeptidase activity
CYB_RS04900	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CYB_RS04910	COG1295	ribonuclease BN
CYB_RS04915	COG0009	L-threonylcarbamoyladenylate synthase
CYB_RS04920	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CYB_RS04960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CYB_RS05000	COG0189	ligase activity
CYB_RS05015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CYB_RS05050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CYB_RS05065	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CYB_RS05080	COG0402	S-adenosylhomocysteine deaminase activity
CYB_RS05095	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CYB_RS05100	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CYB_RS05115	COG2046	Belongs to the sulfate adenylyltransferase family
CYB_RS05125	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CYB_RS05130	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CYB_RS05135	COG0581	inorganic phosphate transmembrane transporter activity
CYB_RS05140	COG0573	inorganic phosphate transmembrane transporter activity
CYB_RS05150	COG0359	binds to the 23S rRNA
CYB_RS05155	COG1372	Participates in initiation and elongation during chromosome replication
CYB_RS05155	COG0305	Participates in initiation and elongation during chromosome replication
CYB_RS05165	COG1691	(AIR) carboxylase
CYB_RS05170	COG0861	Integral membrane protein TerC family
CYB_RS05175	COG1127	ABC transporter
CYB_RS05185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CYB_RS05200	COG3293	Transposase
CYB_RS05210	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CYB_RS05215	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CYB_RS05230	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CYB_RS05260	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CYB_RS05260	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CYB_RS05265	COG0419	ATPase involved in DNA repair
CYB_RS05290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CYB_RS05295	COG0564	pseudouridine synthase activity
CYB_RS05300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CYB_RS05300	COG0574	Belongs to the PEP-utilizing enzyme family
CYB_RS05310	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CYB_RS05315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CYB_RS05340	COG0442	prolyl-tRNA aminoacylation
CYB_RS05345	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CYB_RS05360	COG3437	response regulator, receiver
CYB_RS05375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CYB_RS05380	COG0003	Pfam Anion-transporting ATPase
CYB_RS05410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CYB_RS05415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYB_RS05430	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CYB_RS05435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CYB_RS05465	COG2211	Major facilitator Superfamily
CYB_RS05495	COG0628	permease
CYB_RS05500	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CYB_RS05505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CYB_RS05510	COG0803	Belongs to the bacterial solute-binding protein 9 family
CYB_RS05515	COG1121	(ABC) transporter
CYB_RS05520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CYB_RS05525	COG0724	RNA recognition motif
CYB_RS05530	COG0357	Ribosomal RNA small subunit methyltransferase G
CYB_RS05540	COG0519	Catalyzes the synthesis of GMP from XMP
CYB_RS05540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CYB_RS05555	COG0523	cobalamin synthesis protein
CYB_RS05615	COG0587	DNA-directed DNA polymerase activity
CYB_RS05620	COG0709	Synthesizes selenophosphate from selenide and ATP
CYB_RS05630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYB_RS05655	COG0482	sulfurtransferase activity
CYB_RS05670	COG0515	serine threonine protein kinase
CYB_RS05670	COG1357	PFAM Pentapeptide repeats (8 copies)
CYB_RS05680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CYB_RS05685	COG1305	Transglutaminase-like
CYB_RS05695	COG1846	Transcriptional regulator
CYB_RS05705	COG1079	Belongs to the binding-protein-dependent transport system permease family
CYB_RS05730	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CYB_RS05735	COG1271	oxidase subunit
CYB_RS05740	COG1294	oxidase, subunit
CYB_RS05750	COG0668	transmembrane transport
CYB_RS05755	COG0456	acetyltransferase
CYB_RS05765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CYB_RS05780	COG0336	Belongs to the RNA methyltransferase TrmD family
CYB_RS05790	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CYB_RS05795	COG0250	Participates in transcription elongation, termination and antitermination
CYB_RS05800	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CYB_RS05805	COG0081	regulation of translation
CYB_RS05810	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CYB_RS05815	COG0222	ribosome binding
CYB_RS05835	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CYB_RS05845	COG1192	Involved in chromosome partitioning
CYB_RS05855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CYB_RS05860	COG1132	(ABC) transporter
CYB_RS05865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CYB_RS05870	COG0505	Belongs to the CarA family
CYB_RS05875	COG4969	Belongs to the N-Me-Phe pilin family
CYB_RS05895	COG2197	response regulator
CYB_RS05905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CYB_RS05925	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CYB_RS05925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CYB_RS05930	COG5002	protein histidine kinase activity
CYB_RS05940	COG0322	excinuclease ABC activity
CYB_RS05950	COG0069	glutamate synthase activity
CYB_RS05950	COG0067	glutamate synthase
CYB_RS05950	COG0070	glutamate synthase
CYB_RS05955	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CYB_RS05975	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CYB_RS05990	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
CYB_RS05995	COG0436	Aminotransferase
CYB_RS06000	COG1160	GTP binding
CYB_RS06005	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CYB_RS06025	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CYB_RS06030	COG2385	sporulation resulting in formation of a cellular spore
CYB_RS06030	COG2247	cell wall binding repeat
CYB_RS06065	COG3293	Transposase
CYB_RS06075	COG0713	ATP synthesis coupled electron transport
CYB_RS06090	COG0095	Lipoate-protein ligase
CYB_RS06100	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CYB_RS06130	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CYB_RS06135	COG0275	rRNA processing
CYB_RS06170	COG1233	COG1233 Phytoene dehydrogenase and related
CYB_RS06180	COG1176	ABC-type spermidine putrescine transport system, permease component I
CYB_RS06185	COG3842	ATPase activity
CYB_RS06210	COG0237	dephospho-CoA kinase activity
CYB_RS06215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CYB_RS06225	COG1606	tRNA processing
CYB_RS06255	COG0640	Transcriptional regulator
CYB_RS06275	COG1331	Highly conserved protein containing a thioredoxin domain
CYB_RS06280	COG0456	acetyltransferase
CYB_RS06305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CYB_RS06310	COG0275	rRNA processing
CYB_RS06320	COG4206	TonB-dependent receptor
CYB_RS06345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CYB_RS06350	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CYB_RS06355	COG0569	domain protein
CYB_RS06360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CYB_RS06365	COG0857	belongs to the CobB CobQ family
CYB_RS06370	COG0328	RNA-DNA hybrid ribonuclease activity
CYB_RS06390	COG2205	protein histidine kinase activity
CYB_RS06410	COG2048	Heterodisulfide reductase, subunit B
CYB_RS06420	COG0217	transcriptional regulatory protein
CYB_RS06425	COG0393	Putative heavy-metal-binding
CYB_RS06430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CYB_RS06435	COG2197	response regulator
CYB_RS06465	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CYB_RS06475	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CYB_RS06485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CYB_RS06520	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CYB_RS06535	COG2133	pyrroloquinoline quinone binding
CYB_RS06575	COG0285	dihydrofolate synthase activity
CYB_RS06580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CYB_RS06585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CYB_RS06610	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CYB_RS06615	COG0439	Biotin carboxylase
CYB_RS06630	COG0484	heat shock protein binding
CYB_RS06645	COG3932	Exopolysaccharide synthesis, ExoD
CYB_RS06650	COG3266	domain, Protein
CYB_RS06650	COG2911	Protein conserved in bacteria
CYB_RS06650	COG1361	Conserved repeat domain
CYB_RS06655	COG0719	Fe-S assembly protein
CYB_RS06660	COG0396	ATPase activity
CYB_RS06665	COG1970	mechanosensitive ion channel activity
CYB_RS06670	COG0719	Fe-S assembly protein
CYB_RS06680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CYB_RS06695	COG5002	protein histidine kinase activity
CYB_RS06710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CYB_RS06725	COG0529	Catalyzes the synthesis of activated sulfate
CYB_RS06730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CYB_RS06750	COG0436	Aminotransferase
CYB_RS06760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CYB_RS06765	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CYB_RS06770	COG0460	homoserine dehydrogenase
CYB_RS06785	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CYB_RS06795	COG2223	nitrite transmembrane transporter activity
CYB_RS06800	COG0673	inositol 2-dehydrogenase activity
CYB_RS06815	COG0783	Belongs to the Dps family
CYB_RS06820	COG1162	GTPase activity
CYB_RS06825	COG0463	Glycosyl transferase, family 2
CYB_RS06830	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CYB_RS06850	COG1131	(ABC) transporter
CYB_RS06855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CYB_RS06865	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CYB_RS06870	COG1185	polyribonucleotide nucleotidyltransferase activity
CYB_RS06880	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CYB_RS06905	COG0431	NADPH-dependent FMN reductase
CYB_RS06915	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CYB_RS06965	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CYB_RS06980	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CYB_RS07000	COG1007	ATP synthesis coupled electron transport
CYB_RS07025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYB_RS07030	COG0504	CTP synthase activity
CYB_RS07040	COG0667	Aldo Keto reductase
CYB_RS07045	COG2217	Heavy metal translocating P-type atpase
CYB_RS07070	COG2205	protein histidine kinase activity
CYB_RS07080	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CYB_RS07090	COG1640	4-alpha-glucanotransferase
CYB_RS07095	COG3845	ABC transporter
CYB_RS07100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CYB_RS07160	COG0443	Heat shock 70 kDa protein
CYB_RS07180	COG0133	tryptophan synthase activity
CYB_RS07190	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CYB_RS07195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CYB_RS07200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CYB_RS07210	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CYB_RS07215	COG0515	serine threonine protein kinase
CYB_RS07215	COG1357	PFAM Pentapeptide repeats (8 copies)
CYB_RS07220	COG2372	response to copper ion
CYB_RS07240	COG0358	DNA primase activity
CYB_RS07245	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CYB_RS07250	COG1357	PFAM Pentapeptide repeats (8 copies)
CYB_RS07250	COG0515	serine threonine protein kinase
CYB_RS07285	COG1484	DNA-dependent DNA replication
CYB_RS07295	COG0052	Belongs to the universal ribosomal protein uS2 family
CYB_RS07300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CYB_RS07305	COG0402	S-adenosylhomocysteine deaminase activity
CYB_RS07310	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CYB_RS07320	COG0592	DNA-directed DNA polymerase activity
CYB_RS07325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CYB_RS07335	COG0469	pyruvate kinase activity
CYB_RS07355	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CYB_RS07360	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CYB_RS07370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CYB_RS07375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CYB_RS07380	COG1136	(ABC) transporter
CYB_RS07380	COG0577	efflux transmembrane transporter activity
CYB_RS07395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CYB_RS07400	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CYB_RS07435	COG3293	Transposase
CYB_RS07450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CYB_RS07455	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CYB_RS07490	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CYB_RS07495	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CYB_RS07500	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CYB_RS07505	COG0202	RNA polymerase activity
CYB_RS07510	COG0203	ribosomal protein L17
CYB_RS07515	COG0101	tRNA pseudouridine synthase activity
CYB_RS07520	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CYB_RS07525	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CYB_RS07530	COG0254	rRNA binding
CYB_RS07535	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CYB_RS07540	COG1049	propionate catabolic process, 2-methylcitrate cycle
CYB_RS07550	COG0071	Belongs to the small heat shock protein (HSP20) family
CYB_RS07555	COG3842	ATPase activity
CYB_RS07605	COG0633	Ferredoxin
CYB_RS07635	COG0154	amidase activity
CYB_RS07645	COG1929	Belongs to the glycerate kinase type-1 family
CYB_RS07655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CYB_RS07665	COG0659	secondary active sulfate transmembrane transporter activity
CYB_RS07675	COG3659	wide pore channel activity
CYB_RS07685	COG0516	GMP reductase activity
CYB_RS07695	COG0459	protein refolding
CYB_RS07700	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CYB_RS07710	COG0739	heme binding
CYB_RS07715	COG0723	plastoquinol--plastocyanin reductase activity
CYB_RS07740	COG0793	Belongs to the peptidase S41A family
CYB_RS07745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CYB_RS07750	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CYB_RS07760	COG0473	3-isopropylmalate dehydrogenase activity
CYB_RS07765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CYB_RS07770	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CYB_RS07775	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CYB_RS07785	COG1234	tRNA 3'-trailer cleavage
CYB_RS07790	COG0316	Belongs to the HesB IscA family
CYB_RS07795	COG0745	RESPONSE REGULATOR receiver
CYB_RS07805	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CYB_RS07820	COG0019	diaminopimelate decarboxylase activity
CYB_RS07825	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CYB_RS07830	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CYB_RS07840	COG1104	cysteine desulfurase activity
CYB_RS07845	COG0772	Belongs to the SEDS family
CYB_RS07855	COG1129	ABC transporter
CYB_RS07860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CYB_RS07865	COG5001	Diguanylate cyclase
CYB_RS07865	COG3447	MASE1 domain protein
CYB_RS07865	COG5002	protein histidine kinase activity
CYB_RS07875	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CYB_RS07880	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CYB_RS07885	COG1131	(ABC) transporter
CYB_RS07905	COG0589	response to stress
CYB_RS07910	COG2866	Carboxypeptidase
CYB_RS07920	COG0360	Binds together with S18 to 16S ribosomal RNA
CYB_RS07925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CYB_RS07930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CYB_RS07945	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CYB_RS07950	COG0717	Belongs to the dCTP deaminase family
CYB_RS07970	COG3293	Transposase
CYB_RS07985	COG0473	3-isopropylmalate dehydrogenase activity
CYB_RS07995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CYB_RS08005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CYB_RS08015	COG0501	Belongs to the peptidase M48B family
CYB_RS08020	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CYB_RS08035	COG1132	(ABC) transporter
CYB_RS08050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CYB_RS08060	COG0126	phosphoglycerate kinase activity
CYB_RS08065	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CYB_RS08065	COG0493	'glutamate synthase
CYB_RS08070	COG1562	ergosterol biosynthetic process
CYB_RS08080	COG1111	helicase
CYB_RS08080	COG1205	dead DEAH box helicase
CYB_RS08095	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CYB_RS08100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CYB_RS08110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CYB_RS08135	COG0456	acetyltransferase
CYB_RS08150	COG0459	protein refolding
CYB_RS08215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CYB_RS08225	COG4636	protein conserved in cyanobacteria
CYB_RS08250	COG0297	glycogen (starch) synthase activity
CYB_RS08260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CYB_RS08270	COG0488	(ABC) transporter
CYB_RS08285	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CYB_RS08300	COG0010	Belongs to the arginase family
CYB_RS08310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CYB_RS08315	COG1799	cell septum assembly
CYB_RS08320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CYB_RS08325	COG1252	NADH dehydrogenase
CYB_RS08330	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CYB_RS08335	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CYB_RS08345	COG0137	argininosuccinate synthase activity
CYB_RS08360	COG3293	Transposase
CYB_RS08365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CYB_RS08370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CYB_RS08385	COG0644	oxidoreductase
CYB_RS08400	COG4372	Transposase
CYB_RS08405	COG0022	dehydrogenase e1 component
CYB_RS08405	COG0508	dehydrogenase complex catalyzes the overall conversion of
CYB_RS08410	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CYB_RS08430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CYB_RS08430	COG0426	domain, Protein
CYB_RS08465	COG3000	fatty acid hydroxylase
CYB_RS08465	COG0300	oxidoreductase activity
CYB_RS08480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CYB_RS08485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CYB_RS08490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CYB_RS08500	COG0181	hydroxymethylbilane synthase activity
CYB_RS08510	COG1215	transferase activity, transferring glycosyl groups
CYB_RS08515	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CYB_RS08520	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CYB_RS08530	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CYB_RS08535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CYB_RS08540	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CYB_RS08540	COG4451	ribulose bisphosphate carboxylase, small
CYB_RS08545	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CYB_RS08550	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CYB_RS08555	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CYB_RS08560	COG1122	ATPase activity
CYB_RS08580	COG3794	PFAM blue (type 1) copper domain protein
CYB_RS08595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CYB_RS08620	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYB_RS08625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CYB_RS08640	COG0352	thiamine-phosphate diphosphorylase activity
CYB_RS08645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CYB_RS08650	COG0484	heat shock protein binding
CYB_RS08655	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CYB_RS08665	COG0739	heme binding
CYB_RS08670	COG0215	cysteine-tRNA ligase activity
CYB_RS08680	COG1530	ribonuclease E activity
CYB_RS08685	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CYB_RS08700	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CYB_RS08755	COG4401	Chorismate mutase type I
CYB_RS08770	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CYB_RS08785	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CYB_RS08785	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CYB_RS08815	COG2175	clavaminate synthase activity
CYB_RS08845	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CYB_RS08850	COG1216	Glycosyl transferase, family 2
CYB_RS08855	COG0483	inositol monophosphate 1-phosphatase activity
CYB_RS08860	COG0515	serine threonine protein kinase
CYB_RS08875	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CYB_RS08880	COG2226	methyltransferase
CYB_RS08880	COG0596	Alpha beta hydrolase
CYB_RS08880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CYB_RS08910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CYB_RS08915	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CYB_RS08925	COG1192	Involved in chromosome partitioning
CYB_RS08930	COG0436	Aminotransferase
CYB_RS08940	COG2177	Part of the ABC transporter FtsEX involved in
CYB_RS08950	COG1126	abc transporter atp-binding protein
CYB_RS08955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CYB_RS08960	COG0601	transmembrane transport
CYB_RS08970	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CYB_RS08975	COG2884	Cell division ATP-binding protein ftsE
CYB_RS09005	COG1012	belongs to the aldehyde dehydrogenase family
CYB_RS09015	COG2205	protein histidine kinase activity
CYB_RS09025	COG1122	ATPase activity
CYB_RS09030	COG0739	heme binding
CYB_RS09040	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CYB_RS09045	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CYB_RS09050	COG0083	homoserine kinase activity
CYB_RS09055	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CYB_RS09060	COG1028	Short-chain dehydrogenase reductase Sdr
CYB_RS09080	COG0372	Belongs to the citrate synthase family
CYB_RS09085	COG0701	Predicted permease
CYB_RS09100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CYB_RS09105	COG0581	inorganic phosphate transmembrane transporter activity
CYB_RS09110	COG0573	inorganic phosphate transmembrane transporter activity
CYB_RS09115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CYB_RS09120	COG0540	Belongs to the ATCase OTCase family
CYB_RS09125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CYB_RS09140	COG0321	lipoyl(octanoyl) transferase activity
CYB_RS09145	COG3118	belongs to the thioredoxin family
CYB_RS09160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CYB_RS09170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CYB_RS09175	COG0640	Transcriptional regulator
CYB_RS09185	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CYB_RS09190	COG1230	cation diffusion facilitator family transporter
CYB_RS09205	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CYB_RS09210	COG0643	Histidine kinase
CYB_RS09210	COG0784	Response regulator, receiver
CYB_RS09210	COG0643	Histidine kinase
CYB_RS09210	COG2198	Histidine kinase
CYB_RS09210	COG0784	Response regulator, receiver
CYB_RS09210	COG2198	Histidine kinase
CYB_RS09215	COG0840	transmembrane signaling receptor activity
CYB_RS09215	COG2203	Gaf domain
CYB_RS09245	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CYB_RS09250	COG2086	electron transfer activity
CYB_RS09260	COG0018	arginyl-trna synthetase
CYB_RS09280	COG3046	protein related to deoxyribodipyrimidine photolyase
CYB_RS09285	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CYB_RS09295	COG0402	S-adenosylhomocysteine deaminase activity
CYB_RS09325	COG1741	Belongs to the pirin family
CYB_RS09330	COG0802	atpase or kinase
CYB_RS09335	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CYB_RS09340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CYB_RS09345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CYB_RS09350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CYB_RS09350	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CYB_RS09355	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CYB_RS09360	COG1473	amidohydrolase
CYB_RS09395	COG3781	membrane
CYB_RS09410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CYB_RS09415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CYB_RS09420	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CYB_RS09430	COG0859	PFAM glycosyl transferase family 9
CYB_RS09440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CYB_RS09445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CYB_RS09455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CYB_RS09460	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CYB_RS09465	COG0129	dihydroxy-acid dehydratase activity
CYB_RS09480	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CYB_RS09485	COG0644	oxidoreductase
CYB_RS09495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CYB_RS09500	COG2003	Belongs to the UPF0758 family
CYB_RS09505	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CYB_RS09515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CYB_RS09525	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CYB_RS09550	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYB_RS09555	COG1446	asparaginase
CYB_RS09570	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CYB_RS09580	COG0411	ABC transporter
CYB_RS09590	COG0559	Belongs to the binding-protein-dependent transport system permease family
CYB_RS09610	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CYB_RS09625	COG0066	3-isopropylmalate dehydratase activity
CYB_RS09630	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CYB_RS09675	COG1131	(ABC) transporter
CYB_RS09680	COG0745	RESPONSE REGULATOR receiver
CYB_RS09710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CYB_RS09715	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CYB_RS09720	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CYB_RS09730	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CYB_RS09745	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CYB_RS09750	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CYB_RS09760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CYB_RS09775	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CYB_RS09775	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CYB_RS09795	COG1968	undecaprenyl-diphosphatase activity
CYB_RS09820	COG2226	methyltransferase
CYB_RS09835	COG2814	Major facilitator Superfamily
CYB_RS09840	COG0438	transferase activity, transferring glycosyl groups
CYB_RS09845	COG2208	phosphoserine phosphatase activity
CYB_RS09850	COG3293	Transposase
CYB_RS09865	COG0165	Argininosuccinate lyase
CYB_RS09895	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CYB_RS09895	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CYB_RS09905	COG1725	Transcriptional regulator
CYB_RS09910	COG3842	ATPase activity
CYB_RS09920	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CYB_RS09930	COG0559	Belongs to the binding-protein-dependent transport system permease family
CYB_RS09935	COG3293	Transposase
CYB_RS09950	COG3119	arylsulfatase activity
CYB_RS09960	COG1028	Short-chain dehydrogenase reductase Sdr
CYB_RS09965	COG0405	Gamma-glutamyltransferase
CYB_RS09970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CYB_RS09985	COG0431	NADPH-dependent FMN reductase
CYB_RS10000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CYB_RS10005	COG0210	DNA helicase
CYB_RS10010	COG0561	phosphatase activity
CYB_RS10025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CYB_RS10035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CYB_RS10045	COG1181	Belongs to the D-alanine--D-alanine ligase family
CYB_RS10050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CYB_RS10060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CYB_RS10070	COG2239	Acts as a magnesium transporter
CYB_RS10080	COG1285	pathogenesis
CYB_RS10090	COG2119	membrane
CYB_RS10095	COG0792	nuclease activity
CYB_RS10105	COG3688	RNA-binding protein containing a PIN domain
CYB_RS10115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CYB_RS10125	COG0765	amino acid transport
CYB_RS10135	COG1053	succinate dehydrogenase
CYB_RS10140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CYB_RS10150	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CYB_RS10155	COG0242	peptide deformylase activity
CYB_RS10190	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CYB_RS10200	COG1459	type II secretion system
CYB_RS10210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CYB_RS10220	COG4948	Mandelate Racemase Muconate Lactonizing
CYB_RS10240	COG0024	Methionine aminopeptidase
CYB_RS10250	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CYB_RS10255	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CYB_RS10260	COG4447	cellulose binding
CYB_RS10265	COG1773	rubredoxin
CYB_RS10270	COG1716	ATPase activity
CYB_RS10270	COG5001	Diguanylate cyclase
CYB_RS10275	COG0149	triose-phosphate isomerase activity
CYB_RS10290	COG0501	Belongs to the peptidase M48B family
CYB_RS10300	COG1132	(ABC) transporter
CYB_RS10315	COG0039	L-malate dehydrogenase activity
CYB_RS10320	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CYB_RS10335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYB_RS10340	COG0483	inositol monophosphate 1-phosphatase activity
CYB_RS10355	COG1492	cobalamin metabolic process
CYB_RS10365	COG0247	lactate metabolic process
CYB_RS10400	COG1022	Amp-dependent synthetase and ligase
CYB_RS10410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CYB_RS10425	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CYB_RS10440	COG1366	Belongs to the anti-sigma-factor antagonist family
CYB_RS10455	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CYB_RS10460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CYB_RS10465	COG1324	tolerance protein
CYB_RS10470	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CYB_RS10505	COG0196	riboflavin kinase activity
CYB_RS10510	COG0314	molybdopterin synthase activity
CYB_RS10515	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CYB_RS10525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYB_RS10530	COG0646	methionine synthase
CYB_RS10530	COG1410	methionine synthase
CYB_RS10535	COG1177	transmembrane transport
CYB_RS10550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CYB_RS10555	COG0697	spore germination
CYB_RS10560	COG0180	Tryptophanyl-tRNA synthetase
CYB_RS10570	COG0457	Tetratricopeptide repeat
CYB_RS10575	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CYB_RS10585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYB_RS10590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CYB_RS10610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CYB_RS10625	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CYB_RS10660	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CYB_RS10675	COG0706	membrane insertase activity
CYB_RS10685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CYB_RS10695	COG0195	Participates in both transcription termination and antitermination
CYB_RS10700	COG0779	Required for maturation of 30S ribosomal subunits
CYB_RS10715	COG3293	Transposase
CYB_RS10720	COG2226	methyltransferase
CYB_RS10725	COG0010	Belongs to the arginase family
CYB_RS10735	COG0450	alkyl hydroperoxide reductase
CYB_RS10750	COG1494	fructose-1,6-bisphosphatase
CYB_RS10755	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CYB_RS10765	COG1217	gtp-binding protein TYPA
CYB_RS10775	COG1058	Belongs to the CinA family
CYB_RS10775	COG1546	Belongs to the CinA family
CYB_RS10785	COG0675	Transposase, IS605 OrfB family
CYB_RS10790	COG0589	response to stress
CYB_RS10795	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CYB_RS10805	COG0716	FMN binding
CYB_RS10815	COG3487	Iron-regulated protein
CYB_RS10825	COG3128	pkhd-type hydroxylase
CYB_RS10830	COG0398	Pfam SNARE associated Golgi protein
CYB_RS10840	COG4106	trans-aconitate 2-methyltransferase activity
CYB_RS10850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CYB_RS10855	COG4243	Vitamin k epoxide reductase
CYB_RS10865	COG0434	BtpA family
CYB_RS10870	COG0167	dihydroorotate dehydrogenase activity
CYB_RS10890	COG0501	Belongs to the peptidase M48B family
CYB_RS10895	COG0735	belongs to the Fur family
CYB_RS10915	COG2119	membrane
CYB_RS10920	COG2119	membrane
CYB_RS10925	COG0528	UMP kinase activity
CYB_RS10930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CYB_RS10935	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CYB_RS10945	COG0583	DNA-binding transcription factor activity
CYB_RS10950	COG0596	Alpha beta hydrolase
CYB_RS10955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CYB_RS10965	COG1575	Belongs to the MenA family. Type 1 subfamily
CYB_RS10985	COG0033	Phosphoglucomutase
CYB_RS10995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CYB_RS11010	COG0668	transmembrane transport
CYB_RS11030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CYB_RS11035	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CYB_RS11045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CYB_RS11050	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CYB_RS11055	COG1702	phosphate starvation-inducible protein PhoH
CYB_RS11110	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYB_RS11115	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYB_RS11120	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYB_RS11135	COG1472	Belongs to the glycosyl hydrolase 3 family
CYB_RS11140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CYB_RS11145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CYB_RS11150	COG0416	fatty acid biosynthetic process
CYB_RS11160	COG0134	indole-3-glycerol-phosphate synthase activity
CYB_RS11175	COG2217	Heavy metal translocating P-type atpase
CYB_RS11180	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CYB_RS11195	COG0009	L-threonylcarbamoyladenylate synthase
CYB_RS11205	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CYB_RS11210	COG0539	negative regulation of cytoplasmic translation
CYB_RS11220	COG0523	cobalamin synthesis protein
CYB_RS11230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CYB_RS11240	COG1032	radical SAM domain protein
CYB_RS11245	COG1950	PFAM Membrane protein of
CYB_RS11255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CYB_RS11260	COG0798	PFAM Bile acid sodium symporter
CYB_RS11270	COG0037	tRNA processing
CYB_RS11275	COG1420	regulation of RNA biosynthetic process
CYB_RS11280	COG0831	urea catabolic process
CYB_RS11295	COG1193	negative regulation of DNA recombination
CYB_RS11300	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CYB_RS11320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CYB_RS11340	COG1137	ATPase activity
CYB_RS11345	COG0469	pyruvate kinase activity
CYB_RS11365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CYB_RS11370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CYB_RS11380	COG2104	thiamine diphosphate biosynthetic process
CYB_RS11385	COG2022	thiamine diphosphate biosynthetic process
CYB_RS11390	COG2226	methyltransferase
CYB_RS11400	COG0438	transferase activity, transferring glycosyl groups
CYB_RS11405	COG1131	(ABC) transporter
CYB_RS11410	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CYB_RS11415	COG2226	methyltransferase
CYB_RS11420	COG1573	uracil-dna glycosylase
CYB_RS11425	COG0312	modulator of DNA gyrase
CYB_RS11435	COG3293	Transposase
CYB_RS11455	COG0312	modulator of DNA gyrase
CYB_RS11485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CYB_RS11485	COG0512	Glutamine amidotransferase of anthranilate synthase
CYB_RS11505	COG5002	protein histidine kinase activity
CYB_RS11525	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CYB_RS11525	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CYB_RS11540	COG0484	heat shock protein binding
CYB_RS11555	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CYB_RS11560	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CYB_RS11570	COG5398	heme oxygenase
CYB_RS11575	COG0085	RNA polymerase activity
CYB_RS11580	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CYB_RS11585	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CYB_RS11595	COG0351	phosphomethylpyrimidine kinase
CYB_RS11595	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CYB_RS11595	COG0352	thiamine-phosphate diphosphorylase activity
CYB_RS11600	COG5322	oxidoreductase activity
CYB_RS11605	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CYB_RS11625	COG1116	anion transmembrane transporter activity
CYB_RS11630	COG0788	formyltetrahydrofolate deformylase activity
CYB_RS11640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CYB_RS11645	COG0653	protein targeting
CYB_RS11655	COG1090	epimerase
CYB_RS11670	COG0113	porphobilinogen synthase activity
CYB_RS11695	COG0483	inositol monophosphate 1-phosphatase activity
CYB_RS11700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CYB_RS11705	COG0084	hydrolase, TatD family'
CYB_RS11710	COG2203	Gaf domain
CYB_RS11710	COG3706	GGDEF domain
CYB_RS11710	COG4251	negative regulation of phosphorylation
CYB_RS11710	COG5001	Diguanylate cyclase
CYB_RS11755	COG3293	Transposase
CYB_RS11775	COG1175	transmembrane transport
CYB_RS11785	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CYB_RS11790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CYB_RS11795	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CYB_RS11830	COG1191	sigma factor activity
CYB_RS11845	COG1077	Cell shape determining protein MreB Mrl
CYB_RS11865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYB_RS11880	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CYB_RS11885	COG1959	2 iron, 2 sulfur cluster binding
CYB_RS11890	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CYB_RS11895	COG0745	RESPONSE REGULATOR receiver
CYB_RS11900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CYB_RS11910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CYB_RS11920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CYB_RS11935	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CYB_RS11940	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CYB_RS11955	COG0515	serine threonine protein kinase
CYB_RS11960	COG0475	glutathione-regulated potassium exporter activity
CYB_RS11960	COG0589	response to stress
CYB_RS11965	COG0751	glycine-tRNA ligase activity
CYB_RS11970	COG3001	Fructosamine kinase
CYB_RS11995	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CYB_RS12005	COG0542	response to heat
CYB_RS12010	COG0557	exoribonuclease II activity
CYB_RS12015	COG0704	Plays a role in the regulation of phosphate uptake
CYB_RS12035	COG1505	serine-type exopeptidase activity
CYB_RS12040	COG0148	phosphopyruvate hydratase activity
CYB_RS12045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYB_RS12065	COG2010	Cytochrome c
CYB_RS12070	COG2010	Cytochrome c
CYB_RS12080	COG0830	nickel cation binding
CYB_RS12085	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CYB_RS12090	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CYB_RS12110	COG0375	protein maturation
CYB_RS12115	COG0010	Belongs to the arginase family
CYB_RS12120	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CYB_RS12130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CYB_RS12140	COG0557	exoribonuclease II activity
CYB_RS12145	COG0745	RESPONSE REGULATOR receiver
CYB_RS12150	COG0583	DNA-binding transcription factor activity
CYB_RS12165	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CYB_RS12170	COG1381	Involved in DNA repair and RecF pathway recombination
CYB_RS12175	COG0745	RESPONSE REGULATOR receiver
CYB_RS12205	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CYB_RS12210	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CYB_RS12220	COG0735	belongs to the Fur family
CYB_RS12235	COG0484	heat shock protein binding
CYB_RS12240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CYB_RS12245	COG0515	serine threonine protein kinase
CYB_RS12245	COG2815	serine threonine protein kinase
CYB_RS12250	COG1836	PFAM Integral membrane protein DUF92
CYB_RS12255	COG4451	ribulose bisphosphate carboxylase, small
CYB_RS12265	COG1850	ribulose-bisphosphate carboxylase activity
CYB_RS12270	COG0740	serine-type endopeptidase activity
CYB_RS12295	COG1797	cobyrinic acid a,c-diamide synthase activity
CYB_RS12310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CYB_RS12320	COG3293	Transposase
CYB_RS12325	COG0521	Mo-molybdopterin cofactor biosynthetic process
CYB_RS12350	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CYB_RS12355	COG0088	Forms part of the polypeptide exit tunnel
CYB_RS12360	COG0089	rRNA binding
CYB_RS12365	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CYB_RS12370	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CYB_RS12375	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CYB_RS12380	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CYB_RS12385	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CYB_RS12390	COG0255	Belongs to the universal ribosomal protein uL29 family
CYB_RS12395	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CYB_RS12400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CYB_RS12405	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CYB_RS12410	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CYB_RS12415	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CYB_RS12420	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CYB_RS12425	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CYB_RS12430	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CYB_RS12435	COG0200	Binds to the 23S rRNA
CYB_RS12440	COG0201	protein transport
CYB_RS12445	COG0563	adenylate kinase activity
CYB_RS12450	COG0024	Methionine aminopeptidase
CYB_RS12455	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CYB_RS12475	COG0438	transferase activity, transferring glycosyl groups
CYB_RS12490	COG3854	ATPases associated with a variety of cellular activities
CYB_RS12505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CYB_RS12510	COG0672	)-iron permease
CYB_RS12520	COG1122	ATPase activity
CYB_RS12540	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CYB_RS12555	COG3293	Transposase
CYB_RS12580	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CYB_RS12600	COG0354	folic acid binding
CYB_RS12635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CYB_RS12680	COG3293	Transposase
CYB_RS12695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CYB_RS12700	COG1366	Belongs to the anti-sigma-factor antagonist family
CYB_RS12705	COG2226	methyltransferase
CYB_RS12715	COG1840	ABC-type Fe3 transport system, periplasmic component
CYB_RS12725	COG1178	ABC-type Fe3 transport system permease component
CYB_RS12730	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CYB_RS12735	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CYB_RS12740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CYB_RS12745	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CYB_RS12750	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CYB_RS12755	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CYB_RS12765	COG0356	it plays a direct role in the translocation of protons across the membrane
CYB_RS12785	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CYB_RS12795	COG0783	Belongs to the Dps family
CYB_RS12800	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CYB_RS12815	COG0745	RESPONSE REGULATOR receiver
CYB_RS12820	COG1304	FMN binding
CYB_RS12840	COG0277	FAD linked oxidase domain protein
CYB_RS12845	COG0675	Transposase, IS605 OrfB family
CYB_RS12855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CYB_RS12860	COG1845	cytochrome c oxidase, subunit III
CYB_RS12885	COG0347	Belongs to the P(II) protein family
CYB_RS12890	COG0004	ammonium transporteR
CYB_RS12895	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CYB_RS12930	COG0675	Transposase, IS605 OrfB family
CYB_RS12950	COG0606	chelatase, subunit chli
CYB_RS12955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CYB_RS12965	COG5002	protein histidine kinase activity
CYB_RS12970	COG0745	RESPONSE REGULATOR receiver
CYB_RS13000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CYB_RS13005	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CYB_RS13015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CYB_RS13020	COG0728	peptidoglycan biosynthetic process
CYB_RS13030	COG1413	lyase activity
CYB_RS13080	COG0494	nUDIX hydrolase
CYB_RS13085	COG0784	Response regulator, receiver
CYB_RS13100	COG2203	Gaf domain
CYB_RS13100	COG0840	transmembrane signaling receptor activity
CYB_RS13105	COG2198	Histidine kinase
CYB_RS13105	COG0643	Histidine kinase
CYB_RS13105	COG0784	Response regulator, receiver
CYB_RS13120	COG0825	malonyl-CoA metabolic process
CYB_RS13125	COG1555	photosystem II stabilization
CYB_RS13130	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CYB_RS13140	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CYB_RS13180	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CYB_RS13210	COG0724	RNA recognition motif
CYB_RS13215	COG0420	3'-5' exonuclease activity
CYB_RS13230	COG1166	arginine decarboxylase activity
CYB_RS13240	COG0443	Heat shock 70 kDa protein
CYB_RS13245	COG0484	heat shock protein binding
CYB_RS13250	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CYB_RS13260	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CYB_RS13265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CYB_RS13270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CYB_RS13275	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CYB_RS13310	COG5002	protein histidine kinase activity
CYB_RS13325	COG0268	Binds directly to 16S ribosomal RNA
CYB_RS13335	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CYB_RS13350	COG0174	glutamine synthetase
CYB_RS13355	COG0492	ferredoxin-NADP+ reductase activity
CYB_RS13360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CYB_RS13365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CYB_RS13375	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CYB_RS13390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CYB_RS13410	COG2094	Belongs to the DNA glycosylase MPG family
CYB_RS13415	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CYB_RS13420	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CYB_RS13425	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CYB_RS13430	COG0445	tRNA wobble uridine modification
CYB_RS13435	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CYB_RS13455	COG3237	CsbD-like
CYB_RS13460	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CYB_RS13465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CYB_RS13485	COG0351	phosphomethylpyrimidine kinase
CYB_RS13505	COG0408	coproporphyrinogen oxidase activity
CYB_RS13530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CYB_RS13535	COG0277	FAD linked oxidase domain protein
CYB_RS13540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CYB_RS13545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CYB_RS13550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CYB_RS13555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CYB_RS13560	COG0138	bifunctional purine biosynthesis protein purh
CYB_RS13575	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CYB_RS13580	COG0745	RESPONSE REGULATOR receiver
CYB_RS13585	COG0617	tRNA 3'-terminal CCA addition
CYB_RS13590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CYB_RS13605	COG0315	cyclic pyranopterin monophosphate synthase activity
CYB_RS13620	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CYB_RS13625	COG2308	Evidence 4 Homologs of previously reported genes of
CYB_RS13660	COG2154	pterin-4-alpha-carbinolamine dehydratase
CYB_RS13665	COG1090	epimerase
CYB_RS13670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CYB_RS13675	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CYB_RS13685	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CYB_RS13695	COG0312	modulator of DNA gyrase
CYB_RS13700	COG0495	leucyl-tRNA aminoacylation
CYB_RS13705	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CYB_RS13710	COG0572	uridine kinase
CYB_RS13715	COG0363	glucosamine-6-phosphate deaminase activity
CYB_RS13735	COG0335	large ribosomal subunit rRNA binding
CYB_RS13740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CYB_RS13745	COG0577	efflux transmembrane transporter activity
CYB_RS13745	COG1136	(ABC) transporter
CYB_RS13750	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CYB_RS13755	COG0395	ABC-type sugar transport system, permease component
CYB_RS13760	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CYB_RS13765	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CYB_RS13775	COG0233	cytoplasmic translational termination
CYB_RS13780	COG0617	tRNA 3'-terminal CCA addition
CYB_RS13780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CYB_RS13780	COG0517	IMP dehydrogenase activity
CYB_RS13795	COG3956	TIGRFAM MazG family protein
CYB_RS13820	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CYB_RS13825	COG1160	GTP binding
CYB_RS13840	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CYB_RS13845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CYB_RS13855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CYB_RS13860	COG0072	phenylalanine-tRNA ligase activity
CYB_RS13865	COG3409	Peptidoglycan-binding domain 1 protein
CYB_RS13865	COG3429	Glucose-6-phosphate dehydrogenase subunit
CYB_RS13870	COG0166	Belongs to the GPI family
CYB_RS13875	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CYB_RS13885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CYB_RS13890	COG0012	GTP binding
CYB_RS13900	COG0675	Transposase, IS605 OrfB family
CYB_RS13905	COG0745	RESPONSE REGULATOR receiver
CYB_RS13920	COG0667	Aldo Keto reductase
CYB_RS13935	COG4399	Belongs to the UPF0754 family
CYB_RS13940	COG0737	Belongs to the 5'-nucleotidase family
CYB_RS13945	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CYB_RS13950	COG0443	Heat shock 70 kDa protein
CYB_RS13955	COG0484	heat shock protein binding
CYB_RS13965	COG1162	GTPase activity
CYB_RS13980	COG1196	nuclear chromosome segregation
CYB_RS13985	COG0594	ribonuclease P activity
CYB_RS14035	COG1511	domain protein
CYB_RS14035	COG3264	Mechanosensitive ion channel
CYB_RS14040	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CYB_RS14040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CYB_RS14060	COG4968	Prepilin-type N-terminal cleavage methylation domain
CYB_RS14065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CYB_RS14095	COG5002	protein histidine kinase activity
CYB_RS14095	COG2205	protein histidine kinase activity
CYB_RS14095	COG0784	Response regulator, receiver
CYB_RS14110	COG3706	GGDEF domain
CYB_RS14110	COG5001	Diguanylate cyclase
CYB_RS14110	COG4251	negative regulation of phosphorylation
CYB_RS14110	COG2203	Gaf domain
CYB_RS14155	COG1120	ATPase activity
CYB_RS14175	COG1361	Conserved repeat domain